JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, MAY 12, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: Among 14,400 febrile infants ages 8 to 60 days, the prevalence of urinary tract infection (UTI), bacteremia, and bacterial meningitis was lower for infants who tested positive for SARS-CoV-2, particularly infants ages 29 to 60 days and those with normal inflammatory markers. These findings may help inform management of certain febrile infants who test positive for SARS-CoV-2. 

Authors: Paul L. Aronson, M.D., M.H.S., of the Yale School of Medicine in New Haven, Connecticut, is the corresponding author. 

(doi:10.1001/jamanetworkopen.2023.13354)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, MAY 12, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: The findings of this study of 2,165 adolescents from the Netherlands general population suggest that global brain volumetric measures did not differ between adolescents who reported gender diversity and those who did not. However, these findings further suggest that gender diversity in the general population correlates with specific brain morphologic features in the inferior temporal gyrus among youths who are assigned male at birth. Replication of these findings is necessary to elucidate the potential neurobiological basis of gender diversity in the general population. 

Authors: Akhgar Ghassabian, M.D., Ph.D., of the New York University Grossman School of Medicine in New York, is the corresponding author. 

(doi:10.1001/jamanetworkopen.2023.13139)

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JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, MAY 11, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: In this study of more than 45,000 individuals drawn from the French general population, COVID-19–like symptoms, but not SARS-CoV-2 infection, during the first months of the pandemic were associated with an increased occurrence of subsequent depression and anxiety eight months or more after the occurrence of COVID-19–like symptoms, even when SARS-CoV-2 serologic test results were negative. 

Authors: Alexandra Rouquette, M.D., Ph.D., of the Université de Versailles Saint-Quentin-en-Yvelines in Paris, is the corresponding author. 

(doi:10.1001/jamanetworkopen.2023.12892)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, MAY 10, 2023

Media advisory: The full study and commentary are linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: In this secondary analysis of the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial, overweight and obese body mass index (BMI) in early and middle adulthood was associated with an elevated risk of colorectal cancer and non-colorectal gastrointestinal cancers. The results of the current study prompt further exploration into the mechanistic role of obese BMI in carcinogenesis. 

Authors: Holli A. Loomans-Kropp, Ph.D., M.P.H., of Ohio State University in Columbus, is the corresponding author. 

(doi:10.1001/jamanetworkopen.2023.10002)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, MAY 10, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: In this study, key thematic shifts and increases in language related to anxiety, anger, depression, and loneliness were identified in the content posted on social media by academic emergency medicine physicians and resident physicians during the pandemic. Social media may provide a real-time and evolving landscape to evaluate thematic content and linguistics related to emotions and sentiment for health care workers. 

Authors: Anish K. Agarwal, M.D., M.P.H., M.S., of the Penn Medicine Center for Digital Health in Philadelphia, is the corresponding author. 

(doi:10.1001/jamanetworkopen.2023.12708)

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JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, MAY 8, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: This study found that hospitals adjacent to health care delivery organizations affected by ransomware attacks may see increases in patient census and may experience resource constraints affecting time-sensitive care for conditions such as acute stroke. These findings suggest that targeted hospital cyberattacks may be associated with disruptions of health care delivery at nontargeted hospitals within a community and should be considered a regional disaster. 

Authors: Christian Dameff, M.D., M.S., of the University of California, San Diego, is the corresponding author. 

(doi:10.1001/jamanetworkopen.2023.12270)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, MAY 9, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: In this study, patients using medical cannabis reported improvements in health-related quality of life, which were mostly sustained over time. Adverse events were rarely serious but common, highlighting the need for caution with prescribing medical cannabis.

Authors: Thomas R. Arkell, Ph.D., of the Swinburne University of Technology in Melbourne, Victoria, Australia, is the corresponding author.

(doi: 10.1001/jamanetworkopen.2023.12522)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, MAY 5, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: The findings of this study of 766 patients with SARS-CoV-2 infection suggest that patient-reported perceived cognitive deficits in the first 4 weeks of SARS-CoV-2 infection are associated with post–COVID-19 condition (PCC; colloquially known as long COVID) symptoms and that there may be an affective component to PCC in some patients. The underlying reasons for PCC merit additional exploration. 

Authors: Neil Wenger, M.D., M.P.H., of the University of California, Los Angeles, is the corresponding author. 

(doi:10.1001/jamanetworkopen.2023.11974)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, MAY 5, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: In this study of patients with non–small cell lung cancer, quitting smoking early was associated with lower mortality following a lung cancer diagnosis, and the association of smoking history with overall survival may have varied depending on clinical stage at diagnosis, potentially owing to the differing treatment regimens and efficacy associated with smoking exposure following diagnosis. Detailed smoking history collection should be incorporated into future epidemiological and clinical studies to improve lung cancer prognosis and treatment selection. 

Authors: David C. Christiani, M.D., M.P.H., M.S., of Harvard University in Boston, is the corresponding author. 

(doi:10.1001/jamanetworkopen.2023.11966)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, MAY 4, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: In this observational study of 1,340 women with high-risk breast cancer, strongest collective adherence to cancer prevention lifestyle recommendations was associated with significant reductions in disease recurrence and mortality. Education and implementation strategies to help patients adhere to cancer prevention recommendations throughout the cancer care continuum may be warranted in breast cancer. 

Authors: Rikki A. Cannioto, Ph.D., Ed.D., of the Roswell Park Comprehensive Cancer Center in Buffalo, New York, is the corresponding author. 

(doi:10.1001/jamanetworkopen.2023.11673)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, MAY 3, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: The findings of this systematic review and meta-analysis of secondary data from 40 studies suggest that the effectiveness of COVID-19 vaccines against laboratory-confirmed Omicron or Delta infection and symptomatic disease rapidly wanes over time after the primary vaccination cycle and booster dose. These results can inform the design of appropriate targets and timing for future vaccination programs. 

Authors: Piero Poletti, Ph.D., of the Bruno Kessler Foundation in Trento, Italy, is the corresponding author. 

(doi:10.1001/jamanetworkopen.2023.10650)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, MAY 1, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: The results of this study of 1,300 participants suggest that increased physical activity was associated with functional recovery 6 months after stroke. Interventions targeting individuals with decreasing physical activity in the subacute phase of stroke may play a role in improved functional outcomes.

Authors: Dongni Buvarp, M.D., Ph.D., of the University of Gothenburg in Gothenburg, Sweden, is the corresponding author. 

(doi:10.1001/jamanetworkopen.2023.10919)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, MAY 2, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: This study found that most of the national decrease in racial and ethnic disparities in COVID-19 mortality between the initial and Omicron waves was explained by increased mortality among non-Hispanic white adults and changes in the geographic spread of the pandemic. These findings suggest that despite media reports of a decline in disparities, there is a continued need to prioritize racial health equity in the pandemic response.

Authors: Andrew C. Stokes, Ph.D., of the Boston University School of Public Health in Boston, is the corresponding author.

(doi: 10.1001/jamanetworkopen.2023.11098)

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JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, APRIL 28, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: The results of this study of children with parent-reported attention-deficit/hyperactivity disorder (ADHD) suggest that most were not receiving ADHD medications and had never received outpatient mental health care. Gaps in treatment, which were not directly associated with socioeconomic disadvantage, underscore the challenges of improving communication and access to outpatient mental health care for children with ADHD. 

Authors: Mark Olfson, M.D., M.P.H., of Columbia University and the New York State Psychiatric Institute in New York, is the corresponding author. 

(doi:10.1001/jamanetworkopen.2023.10999)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, APRIL 28, 2023

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2023.10696?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=042823

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: The findings of this study suggest that during the COVID-19 pandemic, children and young adults born preterm were more likely to have used health care related to COVID-19 concerns compared with their term-born peers, independent of a history of bronchopulmonary dysplasia or asthma. Further exploration of factors associated with COVID-19–related health care use may facilitate refinement of care models. 

Authors: Elisabeth C. McGowan, M.D., of Brown University in Providence, Rhode Island, is the corresponding author. 

(doi:10.1001/jamanetworkopen.2023.10696)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

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JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, APRIL 26, 2023

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2023.9135?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=042623

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: The findings of this randomized clinical trial including 2,200 adolescents indicate that the NVX-CoV2373 (Novavax, Inc.) COVID-19 vaccine is safe, immunogenic, and efficacious in preventing COVID-19, including the predominant Delta variant, in adolescents. 

Authors: German Anez, M.D., of Novavax, Inc., in Gaithersburg, Maryland, is the corresponding author. 

(doi:10.1001/jamanetworkopen.2023.9135)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, APRIL 26, 2023

Media advisory: The full study and commentary are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2023.8404?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=042623

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: This study found that living in a more economically deprived and socially marginalized area was associated with increased risk of using violence against others. The finding suggests that interventions may need to include investments in neighborhoods with the highest levels of violence to help reduce downstream transmission of violence. 

Authors: Elizabeth C. Pino, Ph.D., of the Boston University School of Medicine, is the corresponding author. 

(doi:10.1001/jamanetworkopen.2023.8404)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

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JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, APRIL 24, 2023

Media advisory: The full study and commentary are linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: In this study that included 167,000 non-hospitalized patients, neutralizing monoclonal antibody (nMAb) treatment for COVID-19 was safe and associated with reductions in emergency department visits, hospitalization, and death, although it was not associated with reduced risk of hospitalization during the Omicron BA.1 epoch. These findings suggest that targeted risk stratification strategies may help optimize future nMAb treatment decisions. 

Authors: Brian Anderson, M.D., of the MITRE Corporation in Bedford, Massachusetts, is the corresponding author. 

(doi:10.1001/jamanetworkopen.2023.9694)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

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