About The Study: Researchers found in this survey study that adolescents were more likely to have received at least one COVID-19 vaccine dose if they had also received at least one human papillomavirus (HPV), meningococcal conjugate, and/or tetanus, diphtheria, and a cellular pertussis (Tdap) vaccine dose. Addressing hesitancy about routine childhood vaccinations may reduce hesitancy about COVID-19 vaccines.
Authors: Cassandra Pingali, M.P.H., M.S., of the Centers for Disease Control and Prevention in Atlanta, is the corresponding author.
(doi:10.1001/jamapediatrics.2022.4877)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Health Forum: JAMA Health Forum has transitioned from an information channel to an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this case-control study of 23,000 symptomatic individuals in King County, Washington, from June 2020 to July 2022, estimated risk factors and symptoms associated with SARS-CoV-2 infection changed over time. There was a shift in reported symptoms between the Delta and Omicron variants as well as reductions in the protection provided by vaccines. Racial and sociodemographic disparities persisted in the third year of SARS-CoV-2 circulation and were also present in rhinovirus infection. Trends in testing behavior and availability may influence these results.
Authors: Chelsea Hansen, M.P.H., of the National Institutes of Health in Bethesda, Maryland, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.44679)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: This nationally representative cohort study found associations of current combustible tobacco use with the incidence of adverse oral health outcomes and also found an association between current electronic nicotine delivery systems use and the incidence of bleeding after brushing or flossing. These findings highlight the importance of longitudinal studies and emphasize the continued importance of tobacco cessation counseling and resources in clinical practice.
Authors: Marushka L. Silveira, B.D.S., M.P.H., Ph.D., of the National Institutes of Health in Bethesda, Maryland, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.45909)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: Researchers found in this quality improvement study that a program to assist patients in overcoming barriers to video visit access was associated with significant improvement in video visit adherence with a net financial gain. The findings have relevance for efforts to reduce barriers to telehealth-based health care and increase equity.
Authors: Oren J. Mechanic, M.D., M.P.H., of Beth Israel Deaconess Medical Center in Boston, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.45615)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About The Study: This review of 75 publications examining patient inequities within the field of ophthalmology revealed substantial research gaps regarding health inequities associated with the lesbian, gay, bisexual, transgender, and queer (LGBTQ) community, race and ethnicity—namely, American Indian and Alaska Native, Asian, and Native Hawaiian and Other Pacific Islander individuals—and the role of telemedicine for rural and under-resourced areas. Future studies should examine barriers to clinical study and medical trainee recruitment as well as patient values and preference studies and investigate the implementation of telemedicine in under-resourced areas.
Authors: Christian Hemmerich, B.S., of the Oklahoma State University Center for Health Sciences in Tulsa, is the corresponding author.
(doi:10.1001/jamaophthalmol.2022.5237)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: Results of this randomized clinical trial that included 4,100 patients with hypertension showed that a multicomponent intervention delivered on a web-based platform improved blood pressure control rate and lowered blood pressure level more than usual care alone. Such a telemedicine program may provide a new, effective way to treat patients with hypertension in the community and may generate public health benefits across diverse populations.
Authors: Zengwu Wang, M.D., Ph.D., of Peking Union Medical College & Chinese Academy of Medical Sciences in Beijing, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.45439)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: During a period in which both the Delta and Omicron variants were circulating, SARS-CoV-2 booster vaccination was associated with significant reductions in SARS-CoV-2 infections, hospitalizations, and the combined end point of hospitalization or death among residents of two U.S. nursing home systems. These findings suggest that administration of vaccine boosters to nursing home residents may have an important role in preventing COVID-19–associated morbidity and mortality.
Authors: Kevin W. McConeghy, Pharm.D., M.S., of the Veterans Administration Medical Center in Providence, Rhode Island, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.45417)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
Visual Abstract
Authors: Lisa M. McAndrew, Ph.D., of the Veterans Affairs New Jersey Health Care System in East Orange, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.45272)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The results of this study suggest a benefit associated with the availability of effective therapies for melanoma in the past decade and further suggest that the use of new pharmacological therapies is associated with a decrease in the melanoma mortality rate in the U.S. population. These data are very encouraging and support the continued development of such therapies. Additionally, the accessibility of these treatments and the associated health care costs needs to be addressed.
Authors: Navkirat Kahlon, M.D., M.P.H., of the University of Toledo College of Medicine and Life Sciences in Toledo, Ohio, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.45269)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this study of 12,600 adults in Hong Kong with COVID-19 who were hospitalized, viral rebound was uncommon in patients taking molnupiravir or nirmatrelvir-ritonavir and was not associated with increased risk of mortality. Given these findings, novel oral antivirals should be considered as a treatment for more patients with COVID-19 in the early phase of the infection.
Authors: Grace Chung-Yan Lui, M.D., of the Chinese University of Hong Kong, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.45086)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About The Study: This systematic review and meta-analysis of 23 studies found low incidence rate and largely favorable early outcomes of COVID-19 mRNA vaccine–associated myopericarditis in adolescents and young adults from a wide range of populations. These findings are reassuring but continued follow-up is warranted.
Authors: Jun Yasuhara, M.D., of Nationwide Children’s Hospital in Columbus, Ohio, and Toshiki Kuno, M.D., Ph.D., of the Albert Einstein College of Medicine in Bronx, New York, are the corresponding authors.
(doi:10.1001/jamapediatrics.2022.4768)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About The Study: In this systematic review and meta-analysis of 122 U.S.-based COVID-19 clinical trials with 176,000 participants, female participants were underrepresented in treatment trials, Asian and Black participants were underrepresented in prevention trials, and Hispanic or Latino participants were overrepresented in treatment trials. Strategies to better ensure diverse representation in COVID-19 studies are needed, especially for prevention trials.
Authors: Hong Xiao, Ph.D., and Joseph M. Unger, Ph.D., M.S., of the Fred Hutchinson Cancer Center in Seattle, are the corresponding authors.
(doi:10.1001/jamainternmed.2022.5600)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About The Study: Researchers found in this study that included 10,775 adults from an ethnically diverse sample that a higher percentage of daily energy consumption of ultraprocessed foods was associated with cognitive decline. These findings support current public health recommendations on limiting ultraprocessed food consumption because of their potential harm to cognitive function.
Authors: Natalia Gomes Goncalves, Ph.D., of the University of Sao Paulo Medical School in Sao Paulo, Brazil, is the corresponding authors.
(doi:10.1001/jamaneurol.2022.4397)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About The Study: Among pregnant and postpartum persons, drug overdose mortality increased approximately 81% from 2017 to 2020, mirroring trends observed among persons of reproductive age overall. Increases in drug overdose mortality were most pronounced in 2020, coinciding with the onset of the COVID-19 pandemic.
Authors: Emilie Bruzelius, M.P.H., of the Columbia University Mailman School of Public Health in New York, is the corresponding author.
(doi:10.1001/jama.2022.17045)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Health Forum: JAMA Health Forum has transitioned from an information channel to an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
About JAMA Health Forum: JAMA Health Forum has transitioned from an information channel to an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
About The Study: This guideline from the International Antiviral (formerly AIDS) Society–USA updates practice recommendations for managing HIV infection, including when to change antiviral regimens; use of preexposure prophylaxis to prevent infection in at-risk persons; care of pregnant persons with HIV, people aging with HIV, and people with substance use disorder and HIV; and new challenges in people with HIV, including COVID-19 and monkeypox virus infection.
Authors: Rajesh T. Gandhi, M.D., of Massachusetts General Hospital and Harvard Medical School in Boston, is the corresponding author.
(doi:10.1001/jama.2022.22246)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The findings of this study suggest that more biosimilars have been marketed in Germany and Switzerland than in the United States. Policies that counter anticompetitive practices in the United States could allow biosimilars to enter the market sooner and could also lower health care costs with improved access. Awareness of biosimilars should be promoted to increase uptake of biosimilars globally.
Authors: Kerstin N. Vokinger, M.D., J.D., Ph.D., L.L.M., of the University of Zurich in Zurich, Switzerland, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.44670)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: An online reporting system at a large academic medical center facilitated identification of the small number of individuals associated with unprofessional behaviors toward trainees and increased awareness of the medical center’s commitment to creating a safe learning environment.
Authors: I. Michael Leitman, M.D., of the Icahn School of Medicine at Mount Sinai in New York, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.44661)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About The Study: The findings of this study suggest that medical marijuana legalization implemented from 2012 to 2017 was associated with a lower rate of opioid dispensing and pain-related hospital events among some adults receiving treatment for newly diagnosed cancer. The nature of these associations and their implications for patient safety and quality of life need to be further investigated.
Authors: Yuhua Bao, Ph.D., of Weill Cornell Medicine in New York, is the corresponding author.
(doi:10.1001/jamaoncol.2022.5623)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this study of 1,000 adults with symptomatic illness, participants in both the COVID-19–positive and COVID-19–negative groups reported persistently poor physical, mental, or social well-being at 3-month follow-up. Although some individuals had clinically meaningful improvements over time, many reported moderate to severe impairments in well-being 3 months later. These results highlight the importance of including a control group of participants with negative COVID-19 results for comparison when examining the sequelae of COVID-19.
Authors: Lauren E. Wisk, Ph.D., of the David Geffen School of Medicine at the University of California in Los Angeles, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.44486)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: Researchers found in this study of a nationwide data set that included 59,000 full-time undergraduate students that those attending fully online classes reported higher levels of psychological distress than students attending a mix of online and in-person classes.
Authors: Cindy H. Liu, Ph.D., of Brigham and Women’s Hospital in Boston, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.44270)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The findings of this survey study of 215 adults suggest that several common phrases are misunderstood when used in a medical setting, with the interpreted meaning frequently the exact opposite of what is intended.
Authors: Michael Pitt, M.D., of the University of Minnesota in Minneapolis, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.42972)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: Researchers found in this study of 1.1 million firearm fatalities in the United States from 1990 to 2021 marked disparities in firearm fatality rates between men and women and by racial and ethnic group, and these disparities increased in recent years. These findings suggest that public health approaches to reduce firearm violence should consider underlying demographic and geographic trends and differences by intent.
Authors: Chris A. Rees, M.D., M.P.H., of the Emory University School of Medicine in Atlanta, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.44221)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this study of 99,000 pregnancies screened for prenatal cannabis use via urine toxicology testing before and during the COVID-19 pandemic in California, prenatal cannabis use was more common among individuals living in areas with greater retail availability of cannabis. Although relative rates increased similarly during the pandemic regardless of local cannabis retail and policy environment, there was a larger absolute increase associated with living closer to a storefront cannabis retailer. Continued monitoring of local cannabis policy, the retail environment, and prenatal cannabis use is needed.
Authors: Kelly C. Young-Wolff, Ph.D., M.P.H., of Kaiser Permanente Northern California in Oakland, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.44086)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About The Study: Researchers found in this secondary analysis of a randomized clinical trial including 8,800 school-age children with a high prevalence of vitamin D deficiency that weekly oral administration of vitamin D for 3 years did not influence growth, body composition, or pubertal development. Vitamin D deficiency is prevalent among children living in temperate climates and has been reported to associate independently with stunting and obesity.
Authors: Davaasambuu Ganmaa, Ph.D., of the Harvard T.H. Chan School of Public Health in Boston, and Adrian R. Martineau, Ph.D., of the Queen Mary University of London, are the corresponding authors.
(doi:10.1001/jamapediatrics.2022.4581)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About The Study: In this study of approximately 2 million births, maternal unintentional injury during pregnancy was associated with an increased risk of cerebral palsy in children, particularly among those who were exposed to maternal injuries that resulted in hospitalization and those who were delivered shortly after the injury. Public health professionals and stakeholders should be aware of these potential long-term consequences on offspring when designing programs and providing recommendations about safety during pregnancy. Early monitoring and developmental assessment of children exposed to maternal injury might be warranted.
Authors: Asma Ahmed, M.D., Ph.D., M.P.H., of the Hospital for Sick Children Research Institute in Toronto, is the corresponding author.
(doi:10.1001/jamapediatrics.2022.4535)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About The Study: The findings of this study comparing robotic liver resection with open liver resection suggest that robotic liver resection is a safe treatment strategy for patients with hepatocellular carcinoma, the most common type of primary liver cancer, and those with compromised liver function while achieving oncologic efficacy.
Authors: Fabrizio Di Benedetto, M.D., and Stefano Di Sandro, M.D., of the University of Modena and Reggio Emilia in Modena, Italy, are the corresponding authors.
(doi:10.1001/jamasurg.2022.5697)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About The Study: The results of this meta-analysis of 286 randomized clinical trials including 9,500 patients suggest that Black and Hispanic men are underrepresented in trials compared with their share of prostate cancer incidence. The representation of Black patients has consistently remained low during the past 2 decades.
Authors: Irbaz Bin Riaz, M.B.B.S., M.S., of Harvard Medical School in Boston, is the corresponding author.
(doi:10.1001/jamaoncol.2022.5511)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The findings of this study suggest that benzodiazepines, compared with alternative pharmacologic treatments for common sleep disorders, were associated with an increased risk of drug overdose among young people ages 10 to 29 during the following 6-month period, especially among those with a recent opioid prescription. Drug overdose is an important safety consideration when treating young people with benzodiazepines.
Authors: Greta A. Bushnell, Ph.D., of the Rutgers University School of Public Health in Piscataway, New Jersey, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.43215)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: Researchers found in this study of 1.5 million children that after adjusting for possible confounders and accounting for possible parental genetic or familial factors, benzodiazepine exposure during pregnancy was not associated with increased risks of autism spectrum disorder or attention-deficit/hyperactivity disorder. These results challenge current assumptions of a potential association of neurodevelopmental disorders with maternal benzodiazepine use before or during pregnancy.
Authors: Yi-Lung Chen, Ph.D., of Asia University in Taichung, Taiwan, and Mong-Liang Lu, M.D., M.S., of Taipei Medical University in Taipei, Taiwan, are the corresponding authors.
(doi:10.1001/jamanetworkopen.2022.43282)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About The Study: Researchers found in this study of 5,034 youth ages 5 to 19 who died by suicide from 2015 to 2016 that the suicide rate increased as county levels of mental health professional shortages increased, after adjusting for county demographic and socioeconomic characteristics. These findings may inform suicide prevention efforts.
Authors: Jennifer A. Hoffmann, M.D., M.S., of Ann & Robert H. Lurie Children’s Hospital of Chicago, is the corresponding author.
(doi:10.1001/jamapediatrics.2022.4419)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this decision analytical model study of a citywide initiative, every $1 invested in the New York City COVID-19 vaccination campaign yielded estimated savings of $10.19 in direct and indirect costs of health outcomes that would have been incurred without vaccination. The findings of this study suggest that COVID-19 vaccination in New York City was associated with reduction in severe outcomes and avoidance of substantial economic losses.
Authors: Alison P. Galvani, Ph.D., of the Yale School of Public Health in New Haven, Connecticut, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.43127)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Health Forum: JAMA Health Forum has transitioned from an information channel to an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this randomized clinical trial that included 945 patients ages 6 to 17, outreach messages delivered via electronic health record patient portals increased the rates of scheduling and completing well child care visits and receiving the COVID-19 vaccine, providing a useful tool to help restore well child care in populations whose care was delayed during the pandemic.
Authors: Anne E. Berset, B.A., of the Cincinnati Children’s Hospital Medical Center, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.42853)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this cross-sectional study of the presence of fans at National Football League (NFL) home games during the 2020-2021 season, results indicated that fan attendance was associated with increased levels of COVID-19 in the counties in which the venues are nested within, as well as in surrounding counties. The spikes in COVID-19 for crowds of over 20,000 people suggest that large events should be handled with extreme caution during public health event(s) where vaccines, on-site testing, and various countermeasures are not readily available to the public.
Authors: Wanda E. Leal, Ph.D., of Sam Houston State University in Huntsville, Texas, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.40132)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Health Forum: JAMA Health Forum has transitioned from an information channel to an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
About The Study: This study including 4.2 million adults in all 50 states from 2010 to 2019 found that recreational cannabis laws may be associated with increased alcohol use, primarily among younger adults and men. These findings suggest that increased alcohol use may be an unintended consequence of recreational cannabis laws.
Authors: Coleman Drake, Ph.D., of the University of Pittsburgh School of Public Health, is the corresponding author.
(doi:10.1001/jamahealthforum.2022.4069)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The results of this study that included 315 women suggest that even moderate physical activity was associated with a 60% lower risk of death among breast cancer survivors. The mortality risk was similar among participants who were active and those with moderate physical activity levels. The findings further suggest that survivorship care plans should consider incorporating physical activity because even moderate activity may be vital for extending survival as well as health-related quality of life.
Authors: Reina Haque, Ph.D., M.P.H., of Kaiser Permanente Southern California in Pasadena, California, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.42660)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About The Study: The findings of this study of 3,110 U.S. counties suggest that residential racial and economic segregation is associated with higher cancer mortality at the county level, highlighting opportunities for geographically targeted cancer prevention and control efforts.
Authors: Lu Zhang, Ph.D., of Clemson University in Clemson, South Carolina, is the corresponding author.
(doi:10.1001/jamaoncol.2022.5382)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About The Study: In this cross-sectional study of data from January 2017 to December 2021, population-based screening and diagnosis remained below pre-pandemic levels for breast, cervical and colorectal cancer. The findings suggest that screening quickly rebounded after the initial stages of the pandemic; however, the longer follow-up time reveals that gaps in preventive cancer screening returned and worsened.
Authors: Allison H. Oakes, Ph.D., of Trilliant Health in Brentwood, Tennessee, is the corresponding author.
(doi:10.1001/jamaoncol.2022.5481)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
