Depression and Heart Failure in US Veterans

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, MAY 8, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this cohort study, depression among veterans was associated with an increased hazard of incident heart failure after controlling for demographic and cardiovascular risk factors. Higher incident heart failure rates in patients with depression remained consistent in an otherwise low-risk cohort.

Corresponding Author: To contact the corresponding author, Evan L. Brittain, MD, MSc, email evan.brittain@vumc.org.

 

(doi:10.1001/jamanetworkopen.2025.9246)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Experiences of Care and Gaslighting in Patients With Vulvovaginal Disorders

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, MAY 8, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.9486?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=050825

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this cross-sectional study, a patient-centered measure of adverse experiences in vulvovaginal care was developed. Participants reported common past experiences with gaslighting (a patient’s concerns are dismissed without proper evaluation) and substantial distress; they frequently considered ceasing care. There is an urgent need for education supporting a biopsychosocial, trauma-informed approach to vulvovaginal pain and continued development of validated instruments to quantify patient experiences.

Corresponding Author: To contact the corresponding author, Chailee F. Moss, MD, email chaileem@gmail.com.

 

(doi:10.1001/jamanetworkopen.2025.9486)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Maternal Cardiometabolic Risk Factors in Pregnancy and Offspring Blood Pressure at Ages 2 to 18

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, MAY 8, 2025

Media advisory: The full study and commentary are linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this cohort study of 12,480 mother-offspring pairs, researchers found that pre-pregnancy obesity, gestational diabetes, and hypertensive disorders of pregnancy, alone or in various combinations, were prospectively associated with higher offspring blood pressure at an early age and with an increased rate of blood pressure change from age 2 to 18 years, with the most profound associations with diastolic blood pressure among female offspring and with systolic blood pressure among Black offspring. These findings suggest that protecting pregnant individuals from cardiometabolic risk factors may promote healthier blood pressure in the next generation.

Corresponding Author: To contact the corresponding author, Shohreh F. Farzan, PhD, email sffarzan@usc.edu.

 

(doi:10.1001/jamanetworkopen.2025.9205)

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Clinical and Neuropathological Evaluations of the New Brunswick Neurological Syndrome of Unknown Cause

Posted by Jim Michalski

JAMA Neurology

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, MAY 7, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaneurology/fullarticle/10.1001/jamaneurol.2025.1718?guestAccessKey=f0ce6d56-973c-4c47-922b-ba20bb733830&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=050725

 

About The Study: There was no evidence supporting a diagnosis of neurological syndrome of unknown cause (NSUC) in this cohort. The data inclusive of independent examinations and neuropathology strongly supported the presence of several neurodegenerative and non-neurodegenerative conditions. Unfounded concerns that a potentially fatal mystery disease, possibly induced by an environmental toxin, is causing the patients’ neurological symptoms has been amplified in traditional and social media. Second, independent clinical evaluations are needed for any patient given a diagnosis of NSUC.

Corresponding Author: To contact the corresponding author, Anthony E. Lang, MD, email anthony.lang@uhn.ca.

 

(doi:10.1001/jamaneurol.2025.1718)

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Real-Time AI-Assisted Insulin Titration System for Glucose Control in Patients With Type 2 Diabetes

Posted by Jim Michalski

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APOE4, Blood Neurodegenerative Biomarkers, and Cognitive Decline in Community-Dwelling Older Adults

Posted by Jim Michalski

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Reporting and Representation of Race and Ethnicity in Clinical Trials of Pharmacotherapy for Mental Disorders

Posted by Jim Michalski

JAMA Psychiatry

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, MAY 7, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapsychiatry/fullarticle/10.1001/jamapsychiatry.2025.0666?guestAccessKey=6a7e637c-9712-4ad0-8e5e-8d7804f08e15&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=050725

 

About The Study: The findings of this meta-analysis suggest that differences in reporting race and ethnicity across geographic locations and underrepresentation of certain racial and ethnic groups in U.S.-based randomized clinical trials highlight the need for international guidelines to ensure equitable recruitment and reporting in clinical trials. 

Corresponding Author: To contact the corresponding author, Alessio Bellato, PhD, email a.bellato@soton.ac.uk.

 

(10.1001/jamapsychiatry.2025.0666)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Vehicle Age and Driver Assistance Technologies in Fatal Crashes Involving Teen and Middle-Aged Drivers

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, MAY 7, 2025

Media advisory: The full study and commentary are linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: The findings of this study suggest that older vehicles and those with fewer driver assistance technologies are associated with increased risk of driver death in fatal crashes; thus, teens should drive the safest vehicles available, not older family cars. The findings underscore the urgent need to ensure teens drive safer vehicles to protect their lives.

Corresponding Author: To contact the corresponding author, Jingzhen Yang, PhD, MPH, email ginger.yang@nationwidechildrens.org.

 

(doi:10.1001/jamanetworkopen.2025.8942)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Immunogenicity and Safety of Influenza and COVID-19 Multicomponent Vaccine in Adults Age 50 and Older

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, MAY 7, 2025

Media advisory: The full study is linked to this news release.

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About The Study: In this phase 3 study, mRNA-1083, an investigational, multicomponent vaccine against seasonal influenza and SARS-CoV-2, met noninferiority criteria and induced higher immune responses than recommended standard care influenza (standard and high dose) and COVID-19 vaccines against all 4 influenza strains (among those ages 50-64), the 3 clinically relevant influenza strains (among those age 65 and older), and SARS-CoV-2 (all ages), with an acceptable tolerability and safety profile.

Corresponding Author: To contact the corresponding author, Amanda K. Rudman Spergel, MD, email Amanda.RudmanSpergel@modernatx.com.

 

(doi:10.1001/jama.2025.5646)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Physician-and Large Language Model–Generated Hospital Discharge Summaries

Posted by Jim Michalski

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Parenting Training Plus Behavioral Treatment for Children With Obesity

Posted by Jim Michalski

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Conversion Therapy Exposure and Elevated Cardiovascular Disease Risk

Posted by Alexandra Marusarz

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, MAY 6, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: In this cohort study of sexual and gender minority (SGM) young adults assigned male at birth, exposure to sexual orientation and gender identity change efforts (SOGICE) was associated with adverse cardiovascular health indicators, including elevated diastolic blood pressure and systolic blood pressure, increased systemic inflammation, and higher odds of self-reported hypertension or high blood pressure. These findings underscore the need for public health and policy interventions to enforce and strengthen bans on SOGICE practices. Recognizing the cardiovascular health consequences of SOGICE contributes to addressing SGM health disparities and emphasizes the importance of affirmative care approaches that prioritize the well-being of SGM individuals.

Corresponding author: To contact the corresponding author, Brian Mustanski, Ph.D., R.N., email brian@northwestern.edu.

 

(doi: 10.1001/jamanetworkopen.2025.8745)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Depressive Symptoms Among US Adults

Posted by Jim Michalski

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, MAY 5, 2025

Media advisory: The full study is linked to this news release.  

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About The Study: In this study, the prevalence of depressive symptoms increased substantially among U.S. adults during the COVID-19 pandemic. Worsening mental health trends were concentrated among younger adults. 

Corresponding Author: To contact the corresponding author, Rishi K. Wadhera, MD, MPP, MPhil, email rwadhera@bidmc.harvard.edu.

 

(doi:10.1001/jamainternmed.2025.0993)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Differences in Abortion Use by Sexual Orientation in 3 National Cohorts

Posted by Alexandra Marusarz

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, MAY 6, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.8644?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=050625

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: In this study using data from retrospectively reported pregnancies from 3 longitudinal cohorts, all sexual minority groups had increased abortion use compared with completely heterosexual participants, and abortion use was heterogeneous; given the higher use of abortion among sexual minority populations, they are more likely to be disproportionately impacted by the narrowing of abortion access in the U.S. after the Supreme Court Dobbs decision. Future research is needed to understand the pathways that contribute to the unique abortion care needs of sexual minority individuals, in order to provide adequate support for abortion seekers.

Corresponding author: To contact the corresponding author, Payal Chakraborty, Ph.D., email pchakraborty@hsph.harvard.edu.

 

(doi: 10.1001/jamanetworkopen.2025.8644)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Parental Technology Use in a Child’s Presence and Health and Development in the Early Years

Posted by Jim Michalski

JAMA Pediatrics

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, MAY 5, 2025

Media advisory: The full study and editorial are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapediatrics/fullarticle/10.1001/jamapediatrics.2025.0682?guestAccessKey=cd4130aa-eed8-48b0-8e50-e7c1b28dbbd8&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=050525

 

About The Study: Parents’ use of technology in their child’s presence was negatively associated with cognitive and psychosocial outcomes and screen time among young children, although the effect sizes were small. Further research focusing on potential impacts on physical activity, sleep, and motor skills is needed. Understanding these associations is crucial for informing research and guidelines aimed at minimizing the potential negative effects of this phenomenon on early childhood development. 

Corresponding Author: To contact the corresponding author, Marcelo Toledo-Vargas, BPhysio (Hons), email mstv798@uowmail.edu.au.

 

(doi:10.1001/jamapediatrics.2025.0682)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Prenatal Cannabis Use and Neonatal Outcomes

Posted by Jim Michalski

JAMA Pediatrics

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, MAY 5, 2025

Media advisory: The full study is linked to this news release.

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About The Study: Cannabis use in pregnancy was associated with greater odds of preterm birth, small for gestational age, and low birth weight even after adjusting for co-use of tobacco products, and confidence in these findings increased from low in the prior review to moderate in the current meta-analysis. The findings of this study may help inform patient counseling and future public health policies. 

Corresponding Author: To contact the corresponding author, Jamie O. Lo, MD, email loj@ohsu.edu.

 

(doi:10.1001/jamapediatrics.2025.0689)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Racial, Ethnic, and Sex Differences in Need and Receipt of Support for Social Needs Among Veterans

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama-health-forum/fullarticle/10.1001/jamahealthforum.2025.0992?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=050225

About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

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Cost-Effectiveness of Universal Routine Depression Screening for Adolescents in Primary Care

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama-health-forum/fullarticle/10.1001/jamahealthforum.2025.0711?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=050225

About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

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State-Level Tax Policy, Cancer Screening, and Mortality Rates in the US

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, MAY 2, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.8455?guestAccessKey=c0957767-f5eb-4d6d-88a4-15c747418b57&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=050225

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this cross-sectional study, tax policy was associated with increased state-level cancer screening rates, as well as decreased cancer mortality rates, which mostly benefited white populations, suggesting that state-level policies may contribute to bridging ongoing cancer care gaps.

Corresponding Author: To contact the corresponding author, Timothy M. Pawlik, MD, PhD, MPH, MTS, MBA, email tim.pawlik@osumc.edu.

 

(doi:10.1001/jamanetworkopen.2025.8455)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Postpartum Care Differences in LGBTQ+ and Non-LGBTQ+ Individuals

Posted by Jim Michalski

JAMA Health Forum

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, MAY 2, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama-health-forum/fullarticle/10.1001/jamahealthforum.2025.0672?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=050225

About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

 

About The Study: Despite similar access to health insurance, lesbian, gay, bisexual, transgender, queer, and other sexual and gender minority (LGBTQ+) people had large inequities in unmet health care needs and cost-related medication nonadherence in the postpartum year. Results suggested LGBTQ+ people receive lower-quality care in the postpartum period. Although use of pregnancy-related care was comparable, LGBTQ+ individuals used more primary and specialist care and were nearly twice as likely to use the emergency department compared with non-LGBTQ+ people.

Corresponding Author: To contact the corresponding author, Kevin H. Nguyen, PhD, email nguyen@bu.edu.

 

(doi:10.1001/jamahealthforum.2025.0672)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Racial and Ethnic Disparities in Receipt of ERBB2-Targeted Therapy for Breast Cancer

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, MAY 1, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.8086?guestAccessKey=c0957767-f5eb-4d6d-88a4-15c747418b57&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=050125

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: The findings of this study suggest a narrowing of racial and ethnic disparities in receipt of ERBB2 (formerly HER2 or HER2/neu)-targeted therapies over time among older Medicare beneficiaries with ERBB2-positive breast cancer. Future research is needed to understand the practices that contributed to the narrowing of racial and ethnic disparities and to develop implementation strategies to effectively improve the quality and equity of breast cancer care.

Corresponding Author: To contact the corresponding author, Utibe R. Essien, MD, MPH, email uessien@mednet.ucla.edu.

 

(doi:10.1001/jamanetworkopen.2025.8086)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Sex- and Race-Specific Prevalence of Hearing Loss Across the Adult Lifespan and Associated Factors

Posted by Jim Michalski

JAMA Otolaryngology–Head & Neck Surgery

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, MAY 1, 2025

Media advisory: The full study and commentary are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaotolaryngology/fullarticle/10.1001/jamaoto.2025.0534?guestAccessKey=7e9e17db-be00-46c2-b18e-e218cf32651a&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=050125

 

About The Study: The prevalence and degree of hearing loss were highest among white male individuals and lowest among Black female individuals in this cohort study of 1,787 adults. Some factors associated with hearing loss, including noise exposure, differed across sex-specific and race-specific groups. Hearing loss is an important public health concern that could be addressed through tailored interventions to reduce its risk across populations.

Corresponding Author: To contact the corresponding author, Lauren K. Dillard, PhD, AuD, email dillalau@musc.edu.

 

(doi:10.1001/jamaoto.2025.0534)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

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Noninfectious Intraocular Inflammation After Intravitreal Aflibercept

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaophthalmology/fullarticle/10.1001/jamaophthalmol.2025.0969?guestAccessKey=cda6c36b-e0d7-4a50-a5a4-5e070dd8d323&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=050125

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Gender Differences in Case Volume Among Ophthalmology Resident Graduates

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaophthalmology/fullarticle/10.1001/jamaophthalmol.2025.0935?guestAccessKey=3689d32e-f298-4012-8f25-bc619ac355f4&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=050125

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Positive Emotion Dysregulation in Opioid Use Disorder and Normalization by Mindfulness-Oriented Recovery Enhancement

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapsychiatry/fullarticle/10.1001/jamapsychiatry.2025.0569?guestAccessKey=e3be7d97-6319-4122-9104-c7d41a33f335&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=043025

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Timing of Complementary Feeding in Preterm Infants and Prevalence of Overweight and Obesity

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.2968?guestAccessKey=5a6cc5c5-5583-4ff0-aa68-7d636e8381d4&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=043025

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Tiered Clinician Vaccine Communication Strategy to Improve Childhood Vaccine Uptake

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.7814?guestAccessKey=a5225178-c020-442b-b3c3-a5b292389432&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=043025

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Generalizability of FDA-Approved AI-Enabled Medical Devices for Clinical Use

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.8052?guestAccessKey=95837248-e895-40d2-9206-ad26cddb7a18&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=043025

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Nicotine Pouch and E-Cigarette Use and Co-Use Among US Youths

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, APRIL 30, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.6739?guestAccessKey=c0957767-f5eb-4d6d-88a4-15c747418b57&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=043025

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this cross-sectional study, commercial nontobacco nicotine use in U.S. 10th and 12th graders shifted from 2023 to 2024, marked by a doubling in nicotine pouch past-30-day use, an increase in pouch plus e-cigarette dual use, and a decrease in exclusive e-cigarette use. Prioritizing surveillance, regulation, and prevention addressing pediatric nicotine pouch use warrants consideration.

Corresponding Author: To contact the corresponding author, Adam M. Leventhal, PhD, email adam.leventhal@usc.edu.

 

(doi:10.1001/jamanetworkopen.2025.6739)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Wildfire Smoke Exposure and Cause-Specific Hospitalization in Older Adults

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, APRIL 30, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.7956?guestAccessKey=c0957767-f5eb-4d6d-88a4-15c747418b57&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=043025

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: Exposure to high levels of smoke pollution was associated with an increase in hospitalizations for respiratory diseases in this cohort study. These findings underscore the need for interventions to mitigate the health impacts of wildfire smoke exposure.

Corresponding Author: To contact the corresponding author, Rachel C. Nethery, PhD, email rnethery@hsph.harvard.edu.

 

(doi:10.1001/jamanetworkopen.2025.7956)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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AI-Enabled Screening for Retinopathy of Prematurity in Low-Resource Settings

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.7831?guestAccessKey=5d075e45-2c7b-4363-bf8b-ea1d769bb3b0&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042925

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Consensus on Adolescent and Young Adult HIV Research Consent in Low- and Middle-Income Countries

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.7879?guestAccessKey=7e14361c-7384-4761-a12b-8487a1af1171&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042925

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Long-Term Efficacy and Cost-Effectiveness of Laser Tonsillotomy vs Tonsillectomy

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.4858?guestAccessKey=b97421dd-0482-4484-8add-bb5e8e7489bd&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042925

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Prenatal and Perinatal Factors of Life’s Essential 8 Cardiovascular Health Trajectories

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, TUESDAY, APRIL 29, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.7774?guestAccessKey=c0957767-f5eb-4d6d-88a4-15c747418b57&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042925

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: Pre-pregnancy overweight or obesity, smoking during pregnancy, and formula-feeding in the first 6 months of life were each associated with adverse cardiovascular health trajectories early in life in this cohort study. Future work should examine whether interventions that address these factors would be effective in optimizing cardiovascular health in children.

Corresponding Author: To contact the corresponding author, Izzuddin M. Aris, PhD, email izzuddin_aris@hphci.harvard.edu.

 

(doi:10.1001/jamanetworkopen.2025.7774)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

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Maternal Hypertension and Adverse Neurodevelopment in a Cohort of Preterm Infants

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, TUESDAY, APRIL 29, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.7788?guestAccessKey=c0957767-f5eb-4d6d-88a4-15c747418b57&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042925

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this preterm cohort study, maternal hypertensive disorders of pregnancy were independently associated with adverse cognitive and language development, with accentuated associations observed in preeclampsia-exposed preterm infants, emphasizing the clinical importance of recognizing hypertensive disorders of pregnancy as a risk, enabling targeted risk management strategies for closer monitoring and aggressive early intervention in affected populations.

Corresponding Author: To contact the corresponding author, Nehal A. Parikh, DO, MS, email nehal.parikh@cchmc.org.

 

(doi:10.1001/jamanetworkopen.2025.7788)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

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Menstrual Cycle Length Changes Following Vaccination Against Influenza Alone or With COVID-19

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, TUESDAY, APRIL 29, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.7871?guestAccessKey=c0957767-f5eb-4d6d-88a4-15c747418b57&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042925

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this cohort study of individuals with regular menstrual cycles, influenza vaccine given alone or in combination with a COVID-19 vaccine was associated with a small but temporary change in menstrual cycle length. These findings may help clinicians confirm the utility of vaccination for patients with concerns about menstrual adverse effects of vaccination.

Corresponding Author: To contact the corresponding author, Alison Edelman, MD, MPH, email edelmana@ohsu.edu.

 

(doi:10.1001/jamanetworkopen.2025.7871)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

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Temporal Trends in the Childhood Opportunity Index at Children’s Hospitals

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapediatrics/fullarticle/10.1001/jamapediatrics.2025.1041?guestAccessKey=3c0e1eb7-3668-4abe-884f-d68ae53540f9&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042725

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Changes in Inhaled Steroid Dispensing to Children After Withdrawal of Brand-Name Fluticasone Propionate

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2025.4154?guestAccessKey=cecb4b72-f815-4796-81c9-53a9c25ad6c0&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042625

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Toward Defining Problematic Media Usage Patterns in Adolescents

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 3:15 P.M. ET, MONDAY, APRIL 28, 2025

Media advisory: The full article is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2025.6113?guestAccessKey=fc50fd0f-5be4-45e1-a5df-7e2030dd1b61&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042825

 

About The Article: This Viewpoint proposes an analogous taxonomy for digital media use that identifies patterns of use, irrespective of content, that could be problematic but, at a minimum, should be flagged as warranting further evaluation and potential remediation.

Corresponding Author: To contact the corresponding author, Dimitri A. Christakis, MD, MPH, email dimitri.christakis@seattlechildrens.org.

 

(doi:10.1001/jama.2025.6113)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Trends in Maternal, Fetal, and Infant Mortality in the US, 2000-2023

Posted by Jim Michalski

JAMA Pediatrics

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, APRIL 28, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapediatrics/fullarticle/10.1001/jamapediatrics.2025.0440?guestAccessKey=6373041a-2cbe-4236-9947-287ec4b8491a&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042825

 

About The Study: The results of this study suggest that maternal health was difficult to track due to changes in reporting practices, but public health emergencies such as the COVID-19 pandemic can have large negative impacts.

Corresponding Author: To contact the corresponding author, Seth Flaxman, PhD, email seth.flaxman@cs.ox.ac.uk.

 

(doi:10.1001/jamapediatrics.2025.0440)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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All-Cause Mortality and Life Expectancy by Birth Cohort Across US States

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, MONDAY, APRIL 28, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.7695?guestAccessKey=c0957767-f5eb-4d6d-88a4-15c747418b57&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042825

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: Cohort-specific patterns across states reveal wide disparities in mortality. Some states have experienced little or no improvements in life expectancy from the 1900 to 2000 birth cohorts. Understanding how mortality patterns vary by birth cohort within each state can inform decision-making around resource allocation and public health interventions.

Corresponding Author: To contact the corresponding author, Theodore R. Holford, PhD, email theodore.holford@yale.edu.

 

(doi:10.1001/jamanetworkopen.2025.7695)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

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Uptake of and Disparities in Semaglutide and Tirzepatide Prescribing for Obesity in the US

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 11 A.M. ET, TUESDAY, APRIL 29, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2025.4735?guestAccessKey=ba29174d-ce24-48f3-926b-02e03bb82ad6&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042925

 

About The Study: Semaglutide and tirzepatide prescriptions within Epic-affiliated health care systems increased slightly between 2021 and 2024, but their uptake remained limited, with only 3% of eligible patients having ever received a prescription during that period. Furthermore, there were disparities in prescribing of varying magnitude based on race and ethnicity, social vulnerability, and urbanicity, although the absolute differences were small compared with the overall underutilization.

Corresponding Author: To contact the corresponding author, Yuan Lu, ScD, email y.lu@yale.edu.

 

(doi:10.1001/jama.2025.4735)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

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Buprenorphine Treatment in Pregnancy and Maternal-Infant Outcomes

Posted by Jim Michalski

JAMA Health Forum

EMBARGOED FOR RELEASE: 4:45 P.M. (ET), SUNDAY, APRIL 27, 2025

Media advisory: The full study is linked to this news release. This study is being presented at the Pediatric Academic Societies 2025 meeting.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama-health-forum/fullarticle/10.1001/jamahealthforum.2025.1814?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=042725

About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

 

About The Study: In this cohort study of pregnant individuals with opioid use disorder, buprenorphine treatment was associated with improved outcomes for the mother and infant, underscoring the need to improve access to treatment nationwide.

Corresponding Author: To contact the corresponding author, Stephen W. Patrick, MD, MPH, MS, email stephen.patrick@emory.edu.

 

(doi:10.1001/jamahealthforum.2025.1814)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

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Alcohol Use Disorder Diagnoses Among Individuals Who Take HIV Preexposure Prophylaxis

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.7295?guestAccessKey=925562d9-557d-4f24-9cf6-f9ffc64caf05&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042525

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Lung Function Trajectory Using Race-Specific vs Race-Neutral Global Lung Function Initiative Coefficients

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.7304?guestAccessKey=3af9a2cd-5ad9-4284-98c2-25e0791a2386&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042525

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Geographic Variation of Racial and Ethnic Differences in Uterine Cancer Survival

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.7227?guestAccessKey=052bffad-cf62-4465-a8ac-992bb920f1b5&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042525

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Public Coverage of Postpartum Services for Immigrants

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama-health-forum/fullarticle/10.1001/jamahealthforum.2025.0702?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=042525

About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

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State and Sociodemographic Trends in US Cigarette Smoking With Future Projections

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, APRIL 25, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.6834?guestAccessKey=c0957767-f5eb-4d6d-88a4-15c747418b57&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042525

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: The findings of these repeated cross-sectional surveys suggest that the difference in cigarette smoking prevalence between historically high vs low prevalence states will shrink by 2035, primarily from much faster declines among young adults in the traditionally highest prevalence states. Slower prevalence declines among older adults are likely to slow the decline in health consequences in these states.

Corresponding Author: To contact the corresponding author, John P. Pierce, PhD, email jppierce@health.ucsd.edu.

 

(doi:10.1001/jamanetworkopen.2025.6834)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Fiscal Impact of Expanded Medicare Coverage for GLP-1 Receptor Agonists to Treat Obesity

Posted by Jim Michalski

JAMA Health Forum

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, APRIL 25, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama-health-forum/fullarticle/10.1001/jamahealthforum.2025.0905?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=042525

About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

 

About The Study: This economic evaluation estimates that expanded Medicare coverage for glucagon-like peptide-1 receptor agonists (GLP-1RAs) would increase access and reduce obesity-related comorbidities but impose substantial costs over 10 years. Even with a moderate scenario (5% uptake, 20% adherence, and 30% additional price discount), net spending was still projected to reach $8 billion over a decade, underscoring the need for further price reductions, lower-cost strategies to prevent weight regain, and reductions in spending on low-value care.

Corresponding Author: To contact the corresponding author, David D. Kim, PhD, email david.kim@bsd.uchicago.edu.

 

(doi:10.1001/jamahealthforum.2025.0905)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Modeling Reemergence of Vaccine-Eliminated Infectious Diseases Under Declining Vaccination in the US

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 11:15 A.M. ET, THURSDAY, APRIL 24, 2025

Media advisory: The full study is linked to this news release.

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https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2025.6495?guestAccessKey=4760b098-4441-478b-8eb5-7009d702a227&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042425

 

About The Study: Based on estimates from this modeling study, declining childhood vaccination rates will increase the frequency and size of outbreaks of previously eliminated vaccine-preventable infections, eventually leading to their return to endemic levels. The timing and critical threshold for returning to endemicity will differ substantially by disease, with measles likely to be the first to return to endemic levels and may occur even under current vaccination levels without improved vaccine coverage and public health response. These findings support the need to continue routine childhood vaccination at high coverage to prevent resurgence of vaccine-preventable infectious diseases in the U.S.

Corresponding Author: To contact the corresponding author, Nathan C. Lo, MD, PhD, email nathan.lo@stanford.edu.

 

(doi:10.1001/jama.2025.6495)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Herpes Zoster Vaccination and Dementia Occurrence

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 4:40 P.M. ET, WEDNESDAY, APRIL 23, 2025

Media advisory: The full study is linked to this news release. This study is being presented at the World Vaccine Congress.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2025.5013?guestAccessKey=f9b03e5d-4caa-4a0c-a7cf-bdbe9c25154a&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042325

 

About The Study: By taking advantage of a quasi-experiment and corroborating findings from Wales in a different population, this study provides evidence of the potential benefits of herpes zoster vaccination for dementia that is more likely to be causal than that of more commonly conducted associational studies.

Corresponding Author: To contact the corresponding author, Pascal Geldsetzer, ScD, MBChB, MPH, email pgeldsetzer@stanford.edu.

 

(doi:10.1001/jama.2025.5013)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Metformin for Knee Osteoarthritis in Patients With Overweight or Obesity

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 7:45 P.M. ET, THURSDAY, APRIL 24, 2025

Media advisory: The full study is linked to this news release. This study is being presented at the Osteoarthritis Research Society International World Congress.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2025.3471?guestAccessKey=311f6f13-a737-426e-8e68-921fffe73bfb&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042425

 

About The Study: The results of this randomized clinical trial support use of metformin for treatment of symptomatic knee osteoarthritis in people with overweight or obesity. Because of the modest sample size, confirmation in a larger clinical trial is warranted.

Corresponding Author: To contact the corresponding author, Flavia M. Cicuttini, PhD, email flavia.cicuttini@monash.edu.

 

(doi:10.1001/jama.2025.3471)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Trends in Mental Health Diagnoses Among Publicly Insured Children

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, APRIL 24, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2025.4605?guestAccessKey=de6371be-8acf-4752-9f5b-d1f3c25f529b&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042425

 

About The Study: The percentage of publicly insured children receiving any mental health or neurodevelopmental disorder diagnosis significantly increased between 2010 and 2019, with increases observed for most diagnostic categories examined. These findings highlight the need for access to appropriate services in safety net systems and other settings that serve this population.

Corresponding Author: To contact the corresponding author, Janet R. Cummings, PhD, email jrcummi@emory.edu.

 

(doi:10.1001/jama.2025.4605)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Health Care Cost Concerns and Hardships for Families of Children With Disabilities

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, APRIL 24, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.7826?guestAccessKey=c0957767-f5eb-4d6d-88a4-15c747418b57&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042425

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: This study contributes to the existing literature by identifying that while insurance coverage is higher among children with disabilities, their families had higher adjusted odds for all of the financial hardships evaluated, compared with families of children without disabilities. This finding suggests that insurance is inadequate for disabled children. These data demonstrate a need to structure health insurance policies to ensure that children with disabilities have their needed medical care covered in a way that is not financially burdensome to families.

Corresponding Author: To contact the corresponding author, Amy J. Houtrow, MD, PhD, MPH, email houtrow@upmc.edu.

 

(doi:10.1001/jamanetworkopen.2025.7826)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Distinct Convergent Brain Alterations in Sleep Disorders and Sleep Deprivation

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapsychiatry/fullarticle/10.1001/jamapsychiatry.2025.0488?guestAccessKey=2e5a4221-77c4-4a26-84d0-a9800468b5cf&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042325

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Long-Term Postoperative Outcomes by Surgeon Gender and Patient-Surgeon Gender Concordance in the US

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamasurgery/fullarticle/10.1001/jamasurg.2025.0866?guestAccessKey=da993ae5-dd59-40db-bdc8-48d938c304fa&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042325

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Cognitive and Functional Decline Among Long-Term Care Residents

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, APRIL 23, 2025

Media advisory: The full study and commentary are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.5635?guestAccessKey=c0957767-f5eb-4d6d-88a4-15c747418b57&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042325

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this study, severe permanent impairment in function and cognition were common and often present near the end of life for long-term care residents, but a minority of residents lived in these states for years. These results suggest that building shared understanding and open communication about the natural course of frailty trajectories for long-term care residents may support resident-centered medical decision-making.

Corresponding Author: To contact the corresponding author, Daniel Kobewka, MD, MSc, email dkobewka@toh.ca.

 

(doi:10.1001/jamanetworkopen.2025.5635)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Screening and Response for Adverse Social Determinants of Health in US Emergency Departments

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, APRIL 23, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.7951?guestAccessKey=c0957767-f5eb-4d6d-88a4-15c747418b57&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042325

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: Despite the high prevalence of adverse social determinants of health (SDOH) in emergency department (ED) populations, in this survey study of 232 EDs, less than one-third performed screening, and one-fifth did not have policies requiring a response to positive screens. Bridging this gap may require expanding adverse SDOH screening practices while also ensuring that EDs have the resources and infrastructure to respond appropriately to identified social needs. Future research might explore advanced technological solutions to enhance screening and responses in these resource-constrained settings.

Corresponding Author: To contact the corresponding author, Melanie F. Molina, MD, MAS, email melanie.molina@ucsf.edu.

 

(doi:10.1001/jamanetworkopen.2025.7951)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Alcohol Use and Abusive or Neglectful Behaviors Among Family Caregivers of Patients With Dementia

Posted by Alexandra Marusarz

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, APRIL 22, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.6211?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=042225

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: In this microlongitudinal cohort study of family caregivers of relatives with dementia, hazardous drinking and daily alcohol consumption were significantly and independently associated with increased odds of abusive and neglectful behaviors, highlighting the need for personalized interventions that address caregiving complexities and alcohol use patterns.

Corresponding author: To contact the corresponding author, Carolyn E. Z. Pickering, Ph.D., R.N., email pickering@uth.tmc.edu.

 

(doi: 10.1001/jamanetworkopen.2025.6211)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Childhood Exposure to Air Pollution, BMI Trajectories, and Insulin Resistance Among Young Adults

Posted by Alexandra Marusarz

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, APRIL 22, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.6431?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=042225

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: In this cohort study of young adults, the long-term association between traffic-related air pollution and insulin resistance may be partially explained by higher body mass index (BMI) and accelerated BMI growth from early adolescence into young adulthood. These findings highlight the importance of weight management in children, particularly those residing in highly polluted areas.

Corresponding author: To contact the corresponding author, Shohreh F. Farzan, Ph.D., email sffarzan@usc.edu.

 

(doi: 10.1001/jamanetworkopen.2025.6431)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Varenicline for Youth Nicotine Vaping Cessation

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, APRIL 23, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2025.3810?guestAccessKey=8c0aa836-0f6d-465e-86ea-178fe0d81e70&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042325

 

About The Study: In this 12-week randomized clinical trial, varenicline, combined with behavioral counseling, increased vaping abstinence in youth who vape nicotine and do not regularly smoke tobacco.

Corresponding Author: To contact the corresponding author, A. Eden Evins, MD, email aeevins@mgh.harvard.edu.

 

(doi:10.1001/jama.2025.3810)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Genomic and Developmental Models to Predict Cognitive and Adaptive Outcomes in Autistic Children

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapediatrics/fullarticle/10.1001/jamapediatrics.2025.0205?guestAccessKey=0dc639e3-fd1b-4e8e-a46a-5ea0c796aa05&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042125

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Trends in Mental and Physical Health Among Youths

Posted by Jim Michalski

JAMA Pediatrics

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, APRIL 21, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapediatrics/fullarticle/10.1001/jamapediatrics.2025.0556?guestAccessKey=39cacfb2-9054-4750-a142-6a7353a21871&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042125

 

About The Study: In this large, nationally representative sample of U.S. youths, the proportions of youths with anxiety or depression increased from 2016 to 2022. In contrast, youth physical health conditions like asthma and severe headache or migraine decreased, while behavioral or conduct problems and heart conditions were consistent. These findings suggest that deterioration in youth health was specific to depression and anxiety but not select physical health conditions. This study aimed to characterize trends in youth health in the U.S., but more work is needed to identify factors associated with observed trends and mechanisms associated with changes. 

Corresponding Author: To contact the corresponding author, Marie E. Heffernan, PhD, email mheffernan@luriechildrens.org.

 

(doi:10.1001/jamapediatrics.2025.0556)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Transcranial Pulsed Current Stimulation and Social Functioning in Children With Autism

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, MONDAY, APRIL 21, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.5776?guestAccessKey=c0957767-f5eb-4d6d-88a4-15c747418b57&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042125

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this randomized clinical trial of prefrontal-cerebellar transcranial pulsed current stimulation in children ages 3 to 14 with autism spectrum disorder, 20 sessions over 4 weeks improved social functioning and sleep. These findings suggest that transcranial pulsed current stimulation may serve as a viable nonpharmacologic alternative for autism spectrum disorder.

Corresponding Author: To contact the corresponding author, Zhenhuan Liu, MD, PhD, email lzh1958424@163.com.

 

(doi:10.1001/jamanetworkopen.2025.5776)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Burnout Trends Among US Health Care Workers

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, MONDAY, APRIL 21, 2025

Media advisory: The full study and commentary are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.5954?guestAccessKey=c0957767-f5eb-4d6d-88a4-15c747418b57&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042125

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this survey study of Veterans Health Administration (VHA) health care workers, burnout and professional stress decreased on average following the pandemic, but burnout levels remain elevated compared with prepandemic levels. The VHA has made several efforts to reduce burnout and stress, and results showed some promise, but exploration of ways to reduce burnout to prepandemic levels is needed.

Corresponding Author: To contact the corresponding author, David C. Mohr, PhD, email david.mohr2@va.gov.

 

(doi:10.1001/jamanetworkopen.2025.5954)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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