Plain Language vs Standard Format for Youth Understanding of COVID-19 Recommendations

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Out-of-Pocket Costs and Payer Types for Buprenorphine Among Youth Ages 12 to 19

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Associations of Different Combinations of Aerobic and Muscle-Strengthening Activity With Mortality

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, AUGUST 7, 2023

Media advisory: The full study is linked to this news release.

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About The Study: This study of 500,000 participants demonstrated that balanced levels of moderate aerobic physical activity, vigorous aerobic physical activity, and muscle strengthening activity combined may be associated with optimal reductions of mortality risk. Higher-than-recommended levels of moderate aerobic physical activity and vigorous aerobic physical activity may further lower the risk of cancer and all-cause mortality, respectively. 

Authors: Rubén López-Bueno, Ph.D., of the University of Zaragoza in Zaragoza, Spain, is the corresponding author.

 

(doi:10.1001/jamainternmed.2023.3093)

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Effects of Cuff Size on the Accuracy of Blood Pressure Readings

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, AUGUST 7, 2023

Media advisory: The full study and commentary are linked to this news release.

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About The Study: Using a regular blood pressure (BP) cuff size for all individuals regardless of arm size resulted in strikingly inaccurate BP readings with an automated device in this randomized crossover trial including 195 adults. This is particularly concerning for settings where one regular BP cuff size is routinely used in all individuals, regardless of arm size. A renewed emphasis on individualized BP cuff selection is warranted. 

Authors: Tammy M. Brady, M.D., Ph.D., of the Johns Hopkins University School of Medicine in Baltimore, is the corresponding author.

 

(doi:10.1001/jamainternmed.2023.3264)

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Probability of 5% or Greater Weight Loss or BMI Reduction Among Adults With Overweight or Obesity

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, AUGUST 7, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: The results of this study of 18.4 million patients in the U.S. with overweight and obesity indicate that the annual probability of 5% or greater weight loss was low (1 in 10) despite the known benefits of clinically meaningful weight loss, but 5% or greater weight loss was more likely than body mass index (BMI) reduction to the healthy weight category, especially for patients with the highest initial BMIs.  

Authors: Lyudmyla Kompaniyets, Ph.D., of the Centers for Disease Control and Prevention in Atlanta, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.27358)

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Use of Medication for Opioid Use Disorder Among Adults With Past-Year Opioid Use Disorder

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, AUGUST 7, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: Despite guidelines recommending medication for opioid use disorder (MOUD), approximately 1 in 5 adults with past-year opioid use disorder received any MOUD, according to data from a 2021 nationally representative  survey. Furthermore, some groups were substantially less likely to receive MOUD, in particular Black adults, women, those unemployed, and those in nonmetropolitan areas. Addressing disparities in MOUD uptake should be prioritized in program, policy, and clinical initiatives. 

Authors: Christopher M. Jones, Pharm.D., Dr.P.H., M.P.H., of the Centers for Disease Control and Prevention in Atlanta, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.27488)

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Sugar-Sweetened and Artificially Sweetened Beverages and Risk of Liver Cancer, Chronic Liver Disease Mortality

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, AUGUST 8, 2023

Media advisory: The full study is linked to this news release.

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About The Study: Among 98,000 postmenopausal women, compared with consuming three or fewer servings of sugar-sweetened beverages per month, those who consumed one or more sugar-sweetened beverages per day had a higher incidence of liver cancer and death from chronic liver disease. Future studies should confirm these findings and identify the biological pathways of these associations.

Authors: Xuehong Zhang, M.B.B.S., Sc.D., of Brigham and Women’s Hospital and Harvard Medical School in Boston, is the corresponding author.

 

(doi:10.1001/jama.2023.12618)

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Management of Acetaminophen Poisoning in the US and Canada

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, AUGUST 8, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: This study provides a consensus statement on consistent evidence-based recommendations for medical, pharmacy, and nursing education and practice to optimize care of patients with acetaminophen poisoning.

Authors: Richard C. Dart, M.D., Ph.D., of the University of Colorado School of Medicine in Denver, is the corresponding author.

 

(doi: 10.1001/jamanetworkopen.2023.27739)

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Association of Radiation Facility Volume With Survival for Men With Very High-Risk Prostate Cancer

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, AUGUST 8, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: The findings of this study suggest that the expertise and resources that accompany high-volume treatment facilities are associated with improved outcomes for men with very high-risk prostate cancer, but further investigation is needed to identify the specific causes for this association.

Authors: Sagar A. Patel, M.D, of Emory University in Atlanta, is the corresponding author.

 

(doi: 10.1001/jamanetworkopen.2023.27637)

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Time From Authorization by the FDA to Medicare Coverage for Novel Technologies

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About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

Racial, Ethnic Disparities in Survival Among People With Second Primary Cancer

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, AUGUST 4, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this study of 230,000 persons with second primary cancers in the U.S., the Black population had a higher risk of death from both cancer and cardiovascular disease compared with the white population, whereas the Hispanic population had a higher risk of death from cancer. These results suggest that research priorities to address survival disparities in the growing population of survivors of multiple primary cancers are warranted. 

Authors: Hyuna Sung, Ph.D., of the American Cancer Society in Atlanta, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.27429)

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Prevalence, Risk Factors for School-Associated Transmission of SARS-CoV-2

JAMA Health Forum

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, AUGUST 4, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

 

About The Study: In this study of Massachusetts schools, the secondary attack rate for SARS-CoV-2 among school-based contacts was low during two periods, and factors associated with transmission risk varied over time. These findings suggest that ongoing surveillance efforts may be essential to ensure that both targeted resources and mitigation practices remain optimal and relevant for disease prevention. 

Authors: Sandra B. Nelson, M.D., of Massachusetts General Hospital in Boston, is the corresponding author.

 

(doi:10.1001/jamahealthforum.2023.2310)

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Efficacy of Telephone-Based Cognitive Behavioral Therapy for Weight Loss, Disordered Eating, and Psychological Distress After Bariatric Surgery

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, AUGUST 3, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: This randomized clinical trial that included 306 adults found that telephone-based cognitive behavioral therapy (tele-CBT) delivered at one year after bariatric surgery resulted in no change in short-term weight outcomes. However, binge eating, emotional eating, and depression and anxiety symptoms were significantly reduced in individuals receiving tele-CBT versus the control group. 

Authors: Sanjeev Sockalingam, M.D., M.H.P.E., of University Health Network in Toronto, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.27099)

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Association of Pregnancy-Specific Alcohol Policies With Infant Morbidities and Maltreatment

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, AUGUST 3, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this study of 1.4 million birthing person–infant pairs in the U.S., most pregnancy-specific alcohol policies were not associated with decreased odds of infant injuries or morbidities. Policy makers should not assume that pregnancy-specific alcohol policies improve infant health. 

Authors: Sarah C. M. Roberts, Dr.P.H., of the University of California, San Francisco, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.27138)

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Evaluation of Field Sobriety Tests for Identifying Drivers Under the Influence of Cannabis

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Outcomes for High-Risk Surgical Procedures Across High- and Low-Competition Hospital Markets

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Perinatal Depression Screening Among Sexual Minority Women

JAMA Psychiatry

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, AUGUST 2, 2023

Media advisory: The full study is linked to this news release.

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About The Study: The findings of this study suggest that, although sexual minority women are at high risk of postpartum depression, their sexual identities are largely undocumented in medical records, highlighting the need for strategies to measure sexual orientation that can reliably capture this information.

Authors: Leiszle Lapping-Carr, Ph.D., of the Northwestern University Feinberg School of Medicine in Chicago, is the corresponding author.

 

(10.1001/jamapsychiatry.2023.2619)

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Comparative Risks of Potential Adverse Events Following COVID-19 mRNA Vaccination Among Older Adults

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, AUGUST 2, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this study of 6.3 million older U.S. adults, the mRNA-1273 (Moderna) vaccine was associated with a slightly lower risk of several adverse events compared with BNT162b2 (Pfizer-BioNTech), possibly due to greater protection against COVID-19. Future research should seek to formally disentangle differences in vaccine safety and effectiveness and consider the role of frailty in assessments of COVID-19 vaccine performance.

Authors: Daniel A. Harris, Ph.D., of the Brown University School of Public Health in Providence, Rhode Island, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.26852)

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Bias-Based Bullying and Elevated Depressive Symptoms Among Asian American, Native Hawaiian, and Pacific Islander LGBTQ+ Youth

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Reducing the Risks of Nuclear War—The Role of Health Professionals

JAMA

EMBARGOED FOR RELEASE: 6:30 P.M. (ET), TUESDAY, AUGUST 1, 2023

Media advisory: The full editorial is linked to this news release. This editorial is being published simultaneously in multiple journals.

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About The Editorial: In this editorial, JAMA and JAMA Network journals join journals worldwide to call on health professionals to warn the public about the major danger to health and essential life support systems posed by the threat of nuclear war and urge action to prevent use of nuclear weapons.

Authors: Chris Zielinski, of the University of Winchester, U.K., and World Association of Medical Editors, is the corresponding author.

 

(doi:10.1001/jama.2023.14519)

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Association of Racial and Ethnic Identity With Attrition From M.D.-Ph.D. Training Programs

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, JULY 31, 2023

Media advisory: The full study is linked to this news release.

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About The Study: This study found significant racial and ethnic disparities in attrition from M.D.-Ph.D. training, where Black students had greater than 50% higher odds of leaving M.D.-Ph.D. training than their peers. Notably, compared with 17% of white students, 29% of Black M.D.-Ph.D. students did not complete their training. 

Authors: Mytien Nguyen, M.S., of the Yale School of Medicine in New Haven, Connecticut, is the corresponding author.

 

(doi:10.1001/jamainternmed.2023.2822)

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Associations of Military-Related Traumatic Brain Injury With New-Onset Mental Health Conditions and Suicide Risk

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, JULY 31, 2023

Media advisory: The full study and commentary are linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this study including 860,000 soldiers, rates of new-onset mental health conditions were higher among individuals with a history of military-related traumatic brain injury (TBI) compared with those without. Moreover, risk for suicide was both directly and indirectly associated with history of TBI.  

Authors: Lisa A. Brenner, Ph.D., of the VHA Rocky Mountain Mental Illness Research Education and Clinical Center in Aurora, Colorado, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.26296)

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Association Between Gestational Age and Academic Achievement of Children Born at Term

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, JULY 31, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: The findings of this study of more than 500,000 children suggest that there is no evidence of a difference in math and reading scores over grades 2 to 11 among children born between 39 and 40 weeks’ gestation, and overall no evidence of better scores among those born at 41 weeks’ gestation compared with 40 weeks’ gestation. The results can further inform decisions on delivery timing at term birth by offering insights into long-term associations of delivery timing with cognitive development and school achievement. 

Authors: George L. Wehby, M.P.H., Ph.D., of the University of Iowa in Iowa City, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.26451)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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USPSTF Recommendation Statement on Folic Acid Supplementation to Prevent Neural Tube Defects

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, AUGUST 1, 2023

Media advisory: To contact the U.S. Preventive Services Task Force, email the Media Coordinator at Newsroom@USPSTF.net or call 301-951-9203. The full report and related articles are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time and all USPSTF articles remain free indefinitely https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2023.12876?guestAccessKey=a80a001a-3225-4474-bd26-3d7bc115b3f6&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=080123

 

Bottom Line: The U.S. Preventive Services Task Force (USPSTF) recommends that all persons planning to or who could become pregnant take a daily supplement containing 0.4 to 0.8 mg (400 to 800 μg) of folic acid. Neural tube defects are among the most common congenital malformations in the U.S., with an estimated 3,000 pregnancies affected each year. Many of these neural tube defects are caused by low folate levels in the body. The USPSTF routinely makes recommendations about the effectiveness of preventive care services and this recommendation is a reaffirmation of its 2017 recommendation statement.

 

(doi:10.1001/jama.2023.12876)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.

Note: More information about the U.S. Preventive Services Task Force, its process, and its recommendations can be found on the newsroom page of its website.

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Urine Drug Screening in a Telehealth Setting for the Treatment of Opioid Use Disorder

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About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

Sociodemographic Disparities in Queue Jumping for Emergency Department Care

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, JULY 28, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this study of emergency department patients in triage, there were consistent disparities among marginalized populations being more likely to experience unexplained queue jumps, hallway placement, and leaving without receiving treatment despite being assigned the same triage acuity as others. Emergency departments should seek to standardize triage processes to mitigate conscious and unconscious biases that may be associated with timely access to emergency care. 

Authors: Rohit B. Sangal, M.D., M.B.A., of the Yale University School of Medicine in New Haven, Connecticut, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.26338)

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Disparities in the Timing of Preoperative Hemodialysis Among Patients With End-Stage Kidney Disease

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, JULY 28, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: This study found significant age-, sex-, race and ethnicity–, and social deprivation–related disparities in the timing of preoperative hemodialysis among patients with end-stage kidney disease. Given that a longer interval between preoperative hemodialysis and surgical procedures is associated with higher postoperative mortality, these findings are concerning and identify a possible avenue to improve equity in surgical outcomes for patients with end-stage kidney disease. 

Authors: Vikram Fielding-Singh, M.D., J.D., of the Stanford University School of Medicine in Stanford, California, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.26326)

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Trends in Alcohol-Related Deaths by Sex

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, JULY 28, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: This study of alcohol-related mortality in the U.S. suggests there has been a significantly higher rate of increase in deaths among female individuals in recent years. These findings underscore the need for further research to understand the specific factors associated with this trend.

Authors: Ibraheem M. Karaye, M.D., Dr.P.H., of Hofstra University in Hempstead, New York, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.26346)

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Prevalence of Hearing Loss, Hearing Aid Use Among Medicare Beneficiaries Age 71 and Older

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, JULY 28, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: The findings of this study suggest that bilateral hearing loss is nearly ubiquitous among older U.S. individuals, prevalence and severity increase with age, and hearing aid use is low. Deeper consideration of discrete severity measures of hearing loss in this population, rather than binary hearing loss terminology, is warranted. 

Authors: Nicholas S. Reed, Au.D., of the Johns Hopkins Bloomberg School of Public Health in Baltimore, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.26320)

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Effect of Exercise on Chemotherapy-Induced Peripheral Neuropathy Among Patients Treated for Ovarian Cancer

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, AUGUST 1, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: The findings of this secondary analysis of a randomized clinical trial suggest that exercise is a promising treatment for chemotherapy-induced peripheral neuropathy (CIPN) and incorporating exercise program referrals into the standard oncology care may reduce CIPN symptoms and increase quality of life for survivors of ovarian cancer.

Authors: Anlan Cao, M.B.B.S., of the Yale School of Public Health in New Haven, Connecticut, is the corresponding author.

 

(doi: 10.1001/jamanetworkopen.2023.26463)

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Race and Treatment Outcomes in Patients With Metastatic Castration-Sensitive Prostate Cancer

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, AUGUST 1, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: The results of this study suggest that providing fair and equal access to health care may reduce the disparities in treatment outcomes between Black and white patients with advanced prostate cancer.

Authors: Neeraj Agarwal, M.D., of the University of Utah in Salt Lake City, is the corresponding author.

 

(doi: 10.1001/jamanetworkopen.2023.26546)

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Evaluation, Comparison of Ophthalmic Scientific Abstracts and References by Current AI Chatbots

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Vigorous Intermittent Lifestyle Physical Activity and Cancer Incidence Among Non-exercising Adults

JAMA Oncology

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, JULY 27, 2023

Media advisory: The full study and editorial are linked to this news release.

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About The Study: The results of this study of 22,000 non-exercising adults indicate that small amounts of vigorous intermittent lifestyle physical activity were associated with lower incident cancer risk. Daily vigorous intermittent lifestyle physical activity may be a promising intervention for cancer prevention in populations not able or motivated to exercise in leisure time. 

Authors: Emmanuel Stamatakis, Ph.D., of the University of Sydney in Sydney, Australia, is the corresponding author. 

 

(doi:10.1001/jamaoncol.2023.1830)

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Disparities in Travel-Related Barriers to Accessing Health Care

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, JULY 27, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: The findings of this study suggest that achieving health equity in access to care will require the removal of access barriers that disproportionately affect socioeconomically disadvantaged and racially minoritized populations. 

Authors: Quoc-Dien Trinh, M.D., M.B.A., of Brigham and Women’s Hospital, Harvard Medical School in Boston, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.25291)

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Childbearing, Infertility, and Career Trajectories Among Women in Medicine

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, JULY 27, 2023

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2023.26192?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=072723

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this survey study, women physicians reported that career-related pressures influenced the timing of childbearing and led to marked alterations to career trajectories to accommodate family building and parenthood. These findings suggest that fertility and family building concerns among women in medicine may contribute to ongoing gender disparities and attrition and represent a potentially critical area for policy reform and future change. 

Authors: Jennifer B. Bakkensen, M.D., of the Northwestern University Feinberg School of Medicine in Chicago, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.26192)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Substances Detected During Coroner Postmortem Toxicology Analyses in Poisoning- and Nonpoisoning-Related Suicides

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Envisioning the Future of Well-Being Efforts for Health Care Workers— Successes and Lessons Learned From the COVID-19 Pandemic

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Use of Wastewater Metrics to Track COVID-19

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, JULY 26, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: The findings of this study including 268 counties in 22 states suggest that wastewater surveillance can provide an accurate assessment of county SARS-CoV-2 incidence and may be the best metric for monitoring amount of circulating virus as home testing increases and disease acuity decreases because of vaccination and treatment.

Authors: Meri R. J. Varkila, M.D., of Stanford University in Palo Alto, California, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.25591)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Low-Dose Aspirin and the Risk of Stroke and Intracerebral Bleeding in Healthy Older People

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, JULY 26, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: This secondary analysis of a randomized clinical trial including 19,000 older adults found a significant increase in intracranial bleeding with daily low-dose aspirin but no significant reduction of ischemic stroke. These findings may have particular relevance to older individuals prone to developing intracranial bleeding after head trauma (e.g., from falls). 

Authors: John J. McNeil, Ph.D., of Monash University in Melbourne, Australia, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.25803)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Characteristics of Emergency Department Visits Among Older Adults With Dementia

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https://jamanetwork.com/journals/jamaneurology/fullarticle/10.1001/jamaneurol.2023.2244?guestAccessKey=5dc18ef4-f483-49c7-8312-5bdeffdaabc1&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=072423

Silicosis Among Immigrant Engineered Stone (Quartz) Countertop Fabrication Workers in California

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State Restrictions and Geographic Access to Gender-Affirming Care for Transgender Youth

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, JULY 25, 2023

Media advisory: The full study is linked to this news release.

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About The Study: State restrictions were associated with significantly increased estimated drive times for youths seeking gender-affirming care. With more than 1 in 4 gender clinics located in states with restrictions, it is unknown whether existing clinics may have capacity to meet the increased need of out-of-state patients.

Authors: Kevin C. Chung, M.D., M.S., of the University of Michigan Medical School in Ann Arbor, is the corresponding author.

 

(doi:10.1001/jama.2023.11299)

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Consumption of Soft Drinks and Overweight and Obesity Among Adolescents in 107 Countries and Regions

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, JULY 24, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: The prevalence of daily consumption of soft drinks was associated with the prevalence of overweight and obesity among adolescent students in this study of 107 countries and regions. These results, in conjunction with other evidence, suggest that reducing soft drink consumption should be a priority in combating adolescent overweight and obesity. 

Authors: Huan Hu, Ph.D., of the National Institute of Occupational Safety and Health in Kanagawa, Japan, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.25158)

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Community Health Worker Home Visiting and Birth Outcomes Among Medicaid Recipients

JAMA Pediatrics

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, JULY 24, 2023

Media advisory: The full study is linked to this news release.

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About The Study: Participation in a home visiting program provided by community health workers working with nurses and social workers, compared with usual care, was associated with reduced risk for adverse birth outcomes, improved prenatal and postnatal care, and reductions in disparities, among birthing individuals with Medicaid. The risk reductions in adverse birth outcomes were greater among Black individuals. 

Authors: Cristian I. Meghea, Ph.D., of Michigan State University in East Lansing, is the corresponding author.

 

(doi:10.1001/jamapediatrics.2023.2310)

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Association of Early-, Middle-, and Late-Life Depression With Incident Dementia

JAMA Neurology

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, JULY 24, 2023

Media advisory: The full study is linked to this news release.

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About The Study: The results of this study of more than 1.4 million adult Danish citizens followed up from 1977 to 2018 suggest that the risk of dementia was more than doubled for both men and women with diagnosed depression. The persistent association between dementia and depression diagnosed in early and middle life suggests that depression may increase dementia risk.

Authors: Holly Elser, M.D., Ph.D., of the Hospital of the University of Pennsylvania in Philadelphia, is the corresponding author.

 

(doi:10.1001/jamaneurol.2023.2309)

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Association of Social Isolation With Hospitalization and Nursing Home Entry Among Older Adults

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, JULY 24, 2023

Media advisory: The full study is linked to this news release.

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About The Study: Social isolation was significantly associated with higher odds of skilled nursing facility stays and nursing home placement during two years, but not with hospitalization, in this nationally representative study of 11,000 older adults. Efforts to deter or delay nursing home entry should seek to enhance social contact at home or in community settings. 

Authors: Mary Louise Pomeroy, Ph.D., M.P.H., of Johns Hopkins University in Baltimore, is the corresponding author.

 

(doi:10.1001/jamainternmed.2023.3064)

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Excess Death Rates for Republican and Democratic Registered Voters in Florida and Ohio During Pandemic

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, JULY 24, 2023

Media advisory: The full study is linked to this news release.

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About The Study: In this study evaluating 538,000 deaths in individuals ages 25 and older in Florida and Ohio between March 2020 and December 2021, excess mortality was significantly higher for Republican voters than Democratic voters after COVID-19 vaccines were available to all adults, but not before. These findings suggest that differences in vaccination attitudes and reported uptake between Republican and Democratic voters may have been factors in the severity and trajectory of the pandemic in the U.S. 

Authors: Jacob Wallace, Ph.D., of the Yale School of Public Health in New Haven, Connecticut, is the corresponding author.

 

(doi:10.1001/jamainternmed.2023.1154)

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DNA Testing Before Tissue Diagnosis and Time to Treatment in Lung Cancer

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, JULY 25, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: The use of plasma circulating tumor DNA testing before tissue diagnosis among patients with suspected advanced lung cancer may expedite biomarker testing and accelerate time to treatment.

Authors: Natasha B. Leighl, M.D., of the University Health Network in Toronto, Ontario, Canada, is the corresponding author.

 

(doi: 10.1001/jamanetworkopen.2023.25332)

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Vegetarian Dietary Patterns and Cardiometabolic Risk in People With or at High Risk of Cardiovascular Disease

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, JULY 25, 2023

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2023.25658?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=072523

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: The results of this study suggest that consuming a vegetarian diet may modestly but significantly improve cardiometabolic outcomes beyond standard pharmacological therapy in individuals at high risk of cardiovascular diseases (CVDs), highlighting the potential protective and synergistic effects of vegetarian diets for the primary prevention of CVD.

Authors: Tian Wang, A.P.D., R.D., of the University of Sydney in Sydney, New South Wales, Australia, is the corresponding author. 

 

(doi: 10.1001/jamanetworkopen.2023.25658)

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Prescribing Patterns of Buprenorphine for Opioid Use Disorder Before, After New Practice Guidelines

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama-health-forum/fullarticle/10.1001/jamahealthforum.2023.1982?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=072123

About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

Association Between Cervical Cancer Screening Guidelines and Preterm Delivery

JAMA Health Forum

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, JULY 21, 2023

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama-health-forum/fullarticle/10.1001/jamahealthforum.2023.1974?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=072123

About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

 

About The Study: The findings of this study of births to females ages 18 to 24 suggest that additional recommended cervical cancer screenings before birth were associated with an increased risk of preterm delivery. Cervical cancer screening guidelines should consider the downstream implications for preterm delivery risk when weighing the population-level costs of screenings against the benefits of reduced cervical cancer mortality. 

Authors: Rebecca Bromley-Dulfano, M.S., of Harvard University Medical School in Cambridge, Massachusetts, is the corresponding author.

 

(doi:10.1001/jamahealthforum.2023.1974)

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Trends in the Prevalence of Hepatitis C Infection During Pregnancy and Maternal-Infant Outcomes

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, JULY 21, 2023

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2023.24770?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=072123

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: This study of more than 70 million births or spontaneous abortions showed the prevalence of hepatitis C (HCV)-positive pregnancies in the U.S. increased 16-fold between 1998 and 2018. Maternal HCV infection was associated with increased odds of preterm labor, poor fetal growth, or fetal distress. These data may support recent recommendations for universal HCV screening with each pregnancy. 

Authors: Po-Hung Chen, M.D., Ph.D., of the Johns Hopkins University School of Medicine in Baltimore, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.24770)

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Evaluating Access to Laser Eye Surgery by Driving Times Using Medicare Data and Geographical Mapping

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaophthalmology/fullarticle/10.1001/jamaophthalmol.2023.3061?guestAccessKey=cdb4bc51-f748-45b8-9139-e1b4ffc8a508&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=072023

Role of Sex in Participation During Virtual Grand Rounds in Ophthalmology

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Exercise With or Without Cognitive Training and Vitamin D to Improve Cognition in Adults with Mild Cognitive Impairment

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, JULY 20, 2023

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2023.24465?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=072023

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: In this randomized clinical trial, older adults with mild cognitive impairment receiving aerobic-resistance exercises with sequential computerized cognitive training significantly improved cognition, although some results were inconsistent. Vitamin D supplementation had no effect. These findings suggest that this multidomain intervention may improve cognition and potentially delay dementia onset in mild cognitive impairment. 

Authors: Manuel Montero-Odasso, M.D., Ph.D., of the Lawson Health Research Institute in London, Ontario, Canada, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.24465)

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Racial, Ethnic Disparities in Receipt of Lifesaving Procedures for Decompensated Cirrhosis

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, JULY 20, 2023

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2023.24539?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=072023

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: In this study of 717,000 admissions for decompensated cirrhosis, there were racial and ethnic disparities in receipt of complex lifesaving procedures and in mortality that persisted over time. 

Authors: Lauren D. Nephew, M.D., M.S.C.E., and Archita P. Desai, M.D., of the Indiana University School of Medicine in Indianapolis, are the corresponding authors. 

 

(doi:10.1001/jamanetworkopen.2023.24539)

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Dementia Risk and Disadvantaged Neighborhoods

JAMA Neurology

EMBARGOED FOR RELEASE: 2:45 A.M. (ET), WEDNESDAY, JULY 19, 2023

Media advisory: The full study is linked to this news release. This study is being released to coincide with presentation at the Alzheimer’s Association International Conference.

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About The Study: The results of this study of 1.6 million patients suggest that residence within more disadvantaged neighborhoods was associated with higher risk of dementia among older veterans integrated in a national health care system.

Authors: Christina S. Dintica, Ph.D., of the University of California, San Francisco, is the corresponding author.

 

(doi:10.1001/jamaneurol.2023.2120)

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