About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this study of 5.6 million U.S. veterans, COVID-19 vaccination coverage through June 2022 was suboptimal. Primary vaccination can be improved among younger, rural-dwelling veterans. Greater uptake of booster vaccination among all veterans is needed.
Authors: Kristina L. Bajema, M.D., M.Sc., of the Veterans Affairs Portland Health Care System in Portland, Oregon, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.54387)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this diagnostic study of an autism screening test including 45,000 children, electronic health record (EHR)-based autism detection achieved clinically meaningful accuracy by age 30 days, improving by age 1. This automated approach could be integrated with caregiver surveys to improve the accuracy of early autism screening.
Authors: Matthew M. Engelhard, M.D., Ph.D., of the Duke University School of Medicine in Durham, North Carolina, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.54303)
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About The Editorial: To address concerns about the use of artificial intelligence (AI) and language models in the writing of manuscripts, JAMA and the JAMA Network journals have updated relevant policies in the journals’ Instructions for Authors.
Authors: Annette Flanagin, R.N., M.A., of JAMA and the JAMA Network in Chicago, is the corresponding author.
(doi:10.1001/jama.2023.1344)
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About The Study: The results of this study of 389,000 participants suggest that estimates of long-term exposure to multiple air pollutants was associated with increased risk of depression and anxiety. Reductions in joint exposure to multiple air pollutants may alleviate the disease burden of depression and anxiety.
Authors: Jing Huang, Ph.D., of the Peking University School of Public Health in Beijing, is the corresponding author.
(10.1001/jamapsychiatry.2022.4812)
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The findings of this study of 363 preterm infants point to the potential use of acoustic cry characteristics in the early identification of risk for long-term developmental and behavioral deficits.
Authors: Barry M. Lester, Ph.D., of the Women and Infants Hospital of Rhode Island in Providence, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.54151)
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: Researchers examined changes in pregnancy-associated deaths in the United States from drugs, homicide, suicide, and other causes from 2018 through 2020.
Authors: Claire E. Margerison, Ph.D., of Michigan State University in East Lansing, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.54287)
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this nationally representative survey study of 19,000 youths, young adults, and adults, substance use decreased between 2019 and 2020 among those ages 13 to 20; consistent declines were not seen in older persons other than tobacco use reductions, and cannabis use increased among adults ages 25 and older. While social changes during the COVID-19 pandemic could have affected substance use, findings should be interpreted with caution due to differences in data collection methods in 2016 to 2019 and 2020.
Authors: Wilson M. Compton, M.D., M.P.E., of the National Institutes of Health in Bethesda, Maryland, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.54566)
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: Implementation of telemedicine was estimated to result in substantial savings in carbon emissions due to driving in this study that included 49,000 telemedicine visits at a National Cancer Institute-designated comprehensive cancer center from April 2020 to June 2021. These results highlight the carbon emissions savings that could be gained with the increased use of telemedicine in oncology.
Authors: Krupal B. Patel, M.D., M.Sc., of the University of South Florida in Tampa, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.53788)
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About The Study: In this systematic review and meta-analysis of 34 studies, individuals with autism had a higher associated risk of developing diabetes, dyslipidemia, and heart disease. The results suggest that clinicians should vigilantly monitor individuals with autism for early signs of cardiometabolic disease and their complications.
Authors: Chanaka N. Kahathuduwa, M.D., M.Phil., Ph.D., of the Texas Tech University Health Sciences Center in Lubbock, is the corresponding author.
(doi:10.1001/jamapediatrics.2022.5629)
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About The Study: Screen use during infancy may contribute to variations in neural activities implicated in the development of high-order cognitive skills, according to the findings of this study involving 437 children. Further efforts are urgently needed to distinguish the direct association of infant screen use compared with family factors that predispose early screen use on executive function impairments.
Authors: Evelyn C. Law, M.D., of the National University of Singapore, is the corresponding author.
(doi:10.1001/jamapediatrics.2022.5674)
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: Among U.S. children and teenagers, from August 1, 2021 to July 31, 2022, COVID-19 ranked eighth among all causes of deaths, fifth in disease-related causes of deaths (excluding unintentional injuries, assault, and suicide), and first in deaths caused by infectious or respiratory diseases. Various factors, including underreporting and not accounting for COVID-19’s role as a contributing cause of death from other diseases, mean that these estimates may understate the true mortality burden of COVID-19.
Authors: Seth Flaxman, Ph.D., of the University of Oxford in Oxford, United Kingdom, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.53590)
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The findings of this study including 1.8 million Medicare beneficiaries suggest that characteristics of a patient’s neighborhood and the hospital where they received treatment were both associated with risk of death after commonly performed inpatient surgical procedures. The associations of these factors on mortality may be additive. Efforts and investments to address variation in postoperative mortality should include both hospital quality improvement as well as addressing drivers of neighborhood deprivation.
Authors: Adrian Diaz, M.D., M.P.H., of Ohio State University in Columbus, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.53620)
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The results of this study suggest that a deep learning model able to distinguish colon carcinoma and acute diverticulitis in computed tomography (CT) images as a support system may significantly improve the diagnostic performance of radiologists, which may improve patient care. As an artificial intelligence support system, the model significantly improved the sensitivity and specificity and reduced the number of false-negative and false-positive findings.
Authors: Sebastian Ziegelmayer, M.D., of the Technical University of Munich in Munich, Germany, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.53370)
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: Researchers examined all-cause and cause-specific mortality rates among pregnant and recently pregnant women in the United States from 2019 to 2020 and compared mortality rates by race and ethnicity.
Authors: Jeffrey T. Howard, Ph.D., of the University of Texas at San Antonio, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.53280)
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About The Study: This study of 1,056 pediatric ophthalmologists found that disparities in access to pediatric ophthalmological care have increased over the past 15 years and are associated with lower socioeconomic status. As patients may rely on online sources to identify the nearest pediatric ophthalmologist, accurate publicly available databases are important.
Authors: Kara M. Cavuoto, M.D., of the University of Miami Miller School of Medicine in Miami, is the corresponding author.
(doi:10.1001/jamaophthalmol.2022.6010)
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: An electronic medical record diabetes screening program in an urban emergency department identified a substantial number of patients with undiagnosed prediabetes and type 2 diabetes or undermanaged disease, particularly racial and ethnic minority individuals and low-income patients. Questions remain including whether this approach could be useful in emergency departments in similar urban settings or rural communities and whether targeting outreach to those with higher hemoglobin A1c levels will be more cost-effective.
Authors: Kirstie K. Danielson, Ph.D., of the University of Illinois Chicago, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.53275)
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: There was no statistically significant difference in the rates of psychosis-related diagnoses or prescribed antipsychotics in states with medical or recreational cannabis policies compared with states with no such policy in this study of commercial and Medicare Advantage claims data from 2003 to 2017. As states continue to introduce new cannabis policies, continued evaluation of psychosis as a potential consequence of state cannabis legalization may be informative.
Authors: Holly Elser, M.D., Ph.D., of the Hospital of the University of Pennsylvania in Philadelphia, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.52689)
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this study of more than 2.6 million births in Denmark between 1978 and 2016, a higher rate of sudden infant death syndrome (SIDS) was observed among siblings of children who died of SIDS compared with the general population. Shared genetic and/or environmental factors may contribute to the observed clustering of SIDS. The family history of SIDS should be considered when assessing SIDS risk in clinical settings.
Authors: Charlotte Glinge, M.D., Ph.D., of Copenhagen University Hospital in Copenhagen, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.52724)
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About The Study: Among predominantly low-income individuals in the southeastern United States, rurality was associated with an increased risk of heart failure among women and Black men, which persisted after adjustment for cardiovascular risk factors and socioeconomic status. This inequity points to a need for additional emphasis on primary prevention of heart failure among rural populations.
Authors: Veronique L. Roger, M.D., M.P.H., of the National Institutes of Health in Bethesda, Maryland, is the corresponding author.
(doi:10.1001/jamacardio.2022.5211)
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: This study analyzed data from 1,463 combat-deployed soldiers and found that reports of being bullied or hazed during deployment were significantly associated with major depressive disorder, intermittent explosive disorder, posttraumatic stress disorder, suicidal thoughts, and substance use disorder. Recognition of these associations may inform efforts to prevent and address mental health problems among service members.
Authors: Laura Campbell-Sills, Ph.D., of the University of California, San Diego, in La Jolla, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.52109)
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The results of this study indicated that clinical outcomes were similar among patients with opioid use disorder who were treated by clinicians with high and low telemedicine use during the COVID-19 pandemic, suggesting that telemedicine is a comparable alternative to in-person opioid use disorder care. There was no evidence that telemedicine was associated with increased access to or improved quality of opioid use disorder treatment.
Authors: Michael L. Barnett, M.D., M.S., of the Harvard T.H. Chan School of Public Health in Boston, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.52381)
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: Family history was perceived as the greatest risk factor for breast cancer in this study of women ages 40 to 76. In interviews, few women perceived breast density as a risk factor, and one-third thought that they could not take any actions to reduce their breast cancer risk. Comprehensive education about breast cancer risks and prevention strategies is needed.
Authors: Christine M. Gunn, Ph.D., of Dartmouth College in Hanover, New Hampshire, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.52209)
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About The Study: In this systematic review and meta-analysis including 17 studies with 10.9 million vaccinated and 2.6 million unvaccinated children ages 5 to 11, mRNA COVID-19 vaccination was associated with lower risks of SARS-CoV-2 infections, severe COVID-19–related illnesses, and hospitalizations due to COVID-19. While vaccination, compared with placebo, was associated with higher incidences of adverse events, the overall frequency of severe adverse events was low.
Authors: Jun Yasuhara, M.D., of Nationwide Children’s Hospital in Columbus, Ohio, and Toshiki Kuno, M.D., Ph.D., of the Albert Einstein College of Medicine in New York, are the corresponding authors.
(doi:10.1001/jamapediatrics.2022.6243)
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: Wait time disparities for outpatient cardiology and orthopedic services increased for Black and Hispanic veterans from the pre–COVID-19 to COVID-19 periods compared with white veterans in this study including 1.1 million veterans.
Authors: Deborah Gurewich, Ph.D., of the Veterans Affairs Boston Healthcare System in Boston, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.52061)
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The findings of this study that included more than 42,000 patients in a large health system suggest that adherence to CDC mRNA monovalent COVID-19 booster dose recommendations among immunocompromised individuals was low. Given the increased risk for severe COVID-19 in this vulnerable population and the well-established additional protection afforded by booster doses, targeted and tailored efforts to ensure that immunocompromised individuals remain up to date with COVID-19 booster dose recommendations are warranted.
Authors: Sara Y. Tartof, Ph.D., M.P.H., of Kaiser Permanente Southern California in Pasadena, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.51833)
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this study of individuals diagnosed with cancer from 43 states during the past 2 decades, researchers found that suicide risks decreased but remained higher compared with the general population. Geographic, racial and ethnic, socioeconomic, and clinical characteristics, some of which are modifiable, contributed to the elevated risks. Timely symptom management and targeted psychosocial interventions are warranted for suicide prevention in individuals diagnosed with cancer.
Authors: Xuesong Han, Ph.D., of the American Cancer Society in Atlanta, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.51863)
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About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
About The Study: Survivors of cancer experienced accelerated declines in physical function after diagnosis, and physical function remained below that of age-matched controls even years later. Patients with cancer may benefit from supportive interventions to preserve physical functioning.
Authors: Elizabeth M. Cespedes Feliciano, Sc.D. S.M., of the Kaiser Permanente Northern California Division of Research in Oakland, is the corresponding author.
(doi:10.1001/jamaoncol.2022.6881)
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The results of this study showed that most children, adolescents and young adults in the continental United States had adequate access to pediatric cancer care in 2021, although disparities existed among racial and ethnic groups and residents in rural areas, areas with high deprivation levels, and some Southern and Midwestern states. Reducing these disparities may require innovative approaches, such as expanding the capabilities of local facilities and creating partnerships with adult oncology centers and primary care physicians.
Authors: Xiaohui Liu, Ph.D., of the University of Utah in Salt Lake City, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.51524)
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: Follow-up colonoscopy rates after a positive stool-based screening test result for colorectal cancer screening were low among an average-risk population in this study that included more than 32,000 individuals from 39 different health care organizations. Socioeconomic factors and the COVID-19 pandemic were associated with lower follow-up colonoscopy rates, presenting opportunities for targeted intervention by clinicians and health care systems.
Authors: Lesley-Ann Miller-Wilson, M.S., Ph.D., M.B.A., of Exact Sciences in Madison, Wisconsin, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.51384)
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this study of 1,832 U.S. adults, the risk of reporting symptoms for 28 or more days after COVID-19 onset was significantly higher in participants who were unvaccinated at the time of infection and those who reported moderate or severe acute illness symptoms. At six months after onset, participants had significantly higher risk of pulmonary, diabetes, neurological, and mental health encounters versus pre-infection baseline.
Authors: Stephanie A. Richard, Ph.D., of the Uniformed Services University of the Health Sciences in Bethesda, Maryland, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.51360)
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About The Study: Among a U.S. national cohort of internal medicine residents, 1 in 4 women vs 1 in 31 men experienced sexual harassment. Most residents understood the process for formally reporting, yet few reported, and even fewer reported to their residency leadership. Less than half were satisfied with the outcome. These findings highlight the need for meaningful action on reports of sexual harassment and mistreatment to create a safer workplace for residents.
Authors: Elizabeth M. Viglianti, M.D., M.P.H., M.Sc., of the University of Michigan in Ann Arbor, is the corresponding author.
(doi:10.1001/jamainternmed.2022.6108)
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About The Study: The results of this study suggest that advanced colorectal neoplasm prevalence at screening colonoscopies conducted 10 or more years after a negative screening colonoscopy is low. Extension of the currently recommended 10-year screening intervals may be warranted, especially for female and younger participants without gastrointestinal symptoms.
Authors: Thomas Heisser, M.Sc., of the German Cancer Research Center in Heidelberg, Germany, is the corresponding author.
(doi:10.1001/jamainternmed.2022.6215)
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