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Coordinated Care to Optimize Cardiovascular Preventive Therapies in Type 2 Diabetes
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Treat-to-Target or High-Intensity Statin in Patients With Coronary Artery Disease
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Parental Nonadherence to Recommendations for COVID-19 Prevention Among Children
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, MARCH 6, 2023
Media advisory: The full study is linked to this news release.
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this survey study of U.S. parents, one-quarter engaged in misrepresentation or nonadherence regarding public health measures for their children. The most common reason was to preserve parental autonomy. Additional reasons included wanting to resume a normal life for their child and the inability to miss work or other responsibilities, among other reasons.
Authors: Andrea Gurmankin Levy, Ph.D., M.B.E., of Middlesex Community College in Middletown, Connecticut, is the corresponding author.
(doi:10.1001/jamanetworkopen.2023.1587)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Cardiovascular Risk Factor Prevalence, Treatment, Control in Young Adults
JAMA
EMBARGOED FOR RELEASE: 11 A.M. (ET), SUNDAY, MARCH 5, 2023
Media advisory: The full study and editorial are linked to this news release.
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About The Study: In this study of nearly 13,000 U.S. adults ages 20 to 44, diabetes and obesity increased from 2009 to March 2020, while hypertension did not change and hyperlipidemia declined. The data from this study show a high and rising burden of most cardiovascular risk factors in young U.S. adults, especially for Black, Hispanic, and Mexican American individuals.
Authors: Rishi K. Wadhera, M.D., M.P.P., M.Phil., of the Beth Israel Deaconess Medical Center in Boston, is the corresponding author.
(doi:10.1001/jama.2023.2307)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Association Between Women’s Exposure to Intimate Partner Violence and Self-reported Health Outcomes in New Zealand
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Race and Ethnicity and Neighborhood Deprivation in Hospitalization Risk in COVID-19
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High-Dose Buprenorphine Initiation in the Emergency Department Among Patients Using Fentanyl and Other Opioids
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Trends and Racial, Geographic Differences in Infant Mortality Due to Necrotizing Enterocolitis
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Changes in Rehabilitation Services in Skilled Nursing Facilities During Pandemic
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About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
Association of Structural Fires in New York City With Inequities in Safe Heating for Immigrant Communities
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, MARCH 3, 2023
Media advisory: The full study is linked to this news release.
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: This study found that the frequency of heating complaints was significantly associated with the frequency of structural fires in New York City. Importantly, this association varied across community districts, with more fires occurring in districts with greater proportions of Black and Latinx residents.
Authors: Clifford C. Sheckter, M.D., of the Santa Clara Valley Medical Center in San Jose, California, is the corresponding author.
(doi:10.1001/jamanetworkopen.2023.1575)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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One-Year Adverse Outcomes Among Adults With Long COVID vs Those Without COVID-19
JAMA Health Forum
EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, MARCH 3, 2023
Media advisory: The full study and editorial are linked to this news release.
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About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
About The Study: This case-control study leveraged a large commercial insurance database and found increased rates of adverse outcomes over a 1-year period for a post–COVID-19 condition (long COVID) cohort surviving the acute phase of illness. The results indicate a need for continued monitoring for at-risk individuals, particularly in the area of cardiovascular and pulmonary management.
Authors: Andrea DeVries, Ph.D., of Elevance Health, Inc., in Indianapolis, is the corresponding author.
(doi:10.1001/jamahealthforum.2023.0010)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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State Variation in Racial and Ethnic Disparities in Incidence of Triple-Negative Breast Cancer
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HPV Vaccination Prevalence, Disproportionate Cancer Burden Among Veterans
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Association of Recent Violence Encounters With Suicidal Ideation Among Adolescents With Depression
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Assessment of Firearm Storage Practices in the US
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Consumer Views on Privacy Protections and Sharing of Personal Digital Health Information
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Trends, Variation in the Use of Active Surveillance for Management of Low-risk Prostate Cancer
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, MARCH 2, 2023
Media advisory: The full study is linked to this news release.
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The results of this study of more than 20,000 men with low-risk prostate cancer suggest that active surveillance rates are rising nationally but are still suboptimal, and wide variation persists across practices and practitioners. Continued progress on this critical quality indicator is essential to minimize overtreatment of low-risk prostate cancer and by extension to improve the benefit-to-harm ratio of national prostate cancer early detection efforts.
Authors: Matthew R. Cooperberg, M.D., M.P.H., of the UCSF Helen Diller Family Comprehensive Cancer Center in San Francisco, is the corresponding author.
(doi:10.1001/jamanetworkopen.2023.1439)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.
Performance of Outpatient Surgical Procedures Before, After Onset of Pandemic
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, MARCH 2, 2023
Media advisory: The full study is linked to this news release.
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The findings of this study suggest that despite calls for the expansion of outpatient surgery to mitigate the growing backlog of surgical cases in the wake of the COVID-19 pandemic, uptake of this practice occurred in only a small subset of operations. Further studies should explore potential barriers to the uptake of this approach, particularly for procedures that have been shown to be safe when performed in an outpatient setting.
Authors: Cornelius A. Thiels, D.O., M.B.A., of the Mayo Clinic in Rochester, Minnesota, is the corresponding author.
(doi:10.1001/jamanetworkopen.2023.1198)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Effect of an Exclusive Human Milk Diet on Gut Microbiome in Preterm Infants
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Association of Interparental Violence and Maternal Depression With Depression Among Adolescents
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Association of Cardiac Biomarkers With Major Adverse Cardiovascular Events in High-risk Patients With Diabetes
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State Cannabis Legalization and Cannabis Use Disorder in the Veterans Health Administration
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Association of Alcohol Abstinence Program With Mortality in Individuals Arrested for Driving While Alcohol Impaired
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Outcomes of Women Undergoing Coronary Artery Bypass Surgery
JAMA Surgery
EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, MARCH 1, 2023
Media advisory: The full study and commentary are linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamasurgery/fullarticle/10.1001/jamasurg.2022.8156?guestAccessKey=69e4ace2-c766-4636-8bb5-c71d601b0397&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=030123
About The Study: The results of this study of more than 1.2 million patients indicate that women remain at significantly higher risk for adverse outcomes following coronary artery bypass grafting and no significant improvement has been seen over the course of the last decade. Further investigation into the determinants of operative outcomes in women is urgently needed.
Authors: Mario Gaudino, M.D., Ph.D., M.S.C.E., of Weill Cornell Medicine in New York, is the corresponding author.
(doi:10.1001/jamasurg.2022.8156)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Reexamining Time From Breast Cancer Diagnosis to Surgery
JAMA Surgery
EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, MARCH 1, 2023
Media advisory: The full study and commentary are linked to this news release.
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About The Study: This case series study using the data of 373,000 patients from the National Cancer Database found that time from breast cancer diagnosis to surgery of greater than eight weeks was associated with worse overall survival. Time to surgery of greater than eight weeks may partly be associated with disadvantageous social determinants of health.
Authors: Heather B. Neuman, M.D., of the University of Wisconsin School of Medicine and Public Health in Madison, is the corresponding author.
(doi:10.1001/jamasurg.2022.8388)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Analysis of Cardiorespiratory Fitness in Early Adulthood and Midlife With Mortality and Fatal or Nonfatal CVD
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Rural-Urban Variation in the Association of Adolescent Violence and Handgun Carrying
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Sex Disparities in Nonacceptance of Statin Therapy and LDL Cholesterol Levels
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Acute and Postacute COVID-19 Outcomes Among Immunologically Naive Adults During Delta vs Omicron Waves
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Clinicians’ and Patients’ Perspectives on Hypertension Care in a Racially and Ethnically Diverse Population
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Gender, Racial, Ethnic Inequities Among Recipients of Multiple NIH Research Project Grants
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, FEBRUARY 28, 2023
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2023.0855?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=022823
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this study of National Institutes of Health (NIH) investigators from 1991 to 2020, researchers found a growing gap among NIH investigators that created a cohort of highly funded NIH investigators. Importantly, there were persistent gender, ethnic, and racial inequities among this elite class of super principal investigators (investigators receiving three or more research project grants). As the NIH develops critical initiatives and reforms to promote equity among its investigators, consideration of the persistent gender and ethnic and racial gaps in this elite class and the influence they have is critical for meaningful reform.
Authors: Mytien Nguyen, M.S., of the Yale School of Medicine in New Haven, Connecticut, is the corresponding author.
(doi:10.1001/jamanetworkopen.2023.0855)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.
Portable Breath-Based Volatile Organic Compound Monitoring for Detection of COVID-19
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, FEBRUARY 28, 2023
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2023.0982?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=022823
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The findings of this diagnostic study with 167 participants suggest that breath analysis has promise for COVID-19 detection. However, similar to rapid antigen testing, the emergence of new variants poses diagnostic challenges. The results of this study warrant additional evaluation on how to overcome these challenges to use breath analysis to improve the diagnosis and care of patients.
Authors: Xudong Fan, Ph.D., and Kevin R. Ward, M.D., of the University of Michigan in Ann Arbor, are the corresponding authors.
(doi:10.1001/jamanetworkopen.2023.0982)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Association of Payment Policy Changes With Medicare Payment to Physicians by Specialty
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Association of Hospice Profit Status With Family Caregivers’ Reported Care Experiences
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Integrating Alcohol-Related Prevention, Treatment Into Primary Care
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Effects of Opt-out vs Opt-in Tobacco Treatment on Engagement, Cessation, Costs
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Estimated Effectiveness of Postpartum mRNA COVID-19 Vaccination Against SARS-CoV-2 Infection, Hospitalization in Infants Younger Than 6 Months
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Cost-effectiveness of Intensive vs Standard Blood Pressure Control Among Older Patients With Hypertension
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Endovascular Ultrasound Renal Denervation to Treat Hypertension
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Association of Cardiovascular Health With Life Expectancy Free of Major Chronic Disease
JAMA Internal Medicine
EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, FEBRUARY 27, 2023
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/10.1001/jamainternmed.2023.0015?guestAccessKey=6e7ff06e-d45e-47b1-8766-44016e07055b&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=022723
About The Study: A high level of cardiovascular health (CVH) was associated with substantially longer life expectancy free of four major chronic diseases (cardiovascular disease, diabetes, cancer, and dementia) in both men and women in this study of 135,000 adults from the UK Biobank study. The disease-free life expectancy was similar between low and other socioeconomic groups among participants with high CVH. These findings support improvement in population health by promoting a high CVH level, which may also narrow health disparities associated with socioeconomic status.
Authors: Lu Qi, M.D., Ph.D., of Tulane University in New Orleans, is the corresponding author.
(doi:10.1001/jamainternmed.2023.0015)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Association of Menthol Flavor Ban With Cigarette Smoking in Massachusetts
JAMA Internal Medicine
EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, FEBRUARY 27, 2023
Media advisory: The full study is linked to this news release.
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About The Study: The Massachusetts comprehensive menthol flavor ban in 2020 was followed by a greater reduction in current cigarette smoking in the state than comparison states overall and among males and Hispanic females while increasing among Black females, according to information from statewide surveys. As the Food and Drug Administration plans to eliminate menthol as a characterizing flavor in cigarettes, interventions should address possible increases in cigarette smoking among Black females.
Authors: Samuel Asare, Ph.D., of the American Cancer Society in Atlanta, is the corresponding author.
(doi:10.1001/jamainternmed.2022.6743)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Myocarditis or Pericarditis After BNT162b2 Vaccination in Youth in Ontario
JAMA Pediatrics
EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, FEBRUARY 27, 2023
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapediatrics/fullarticle/10.1001/jamapediatrics.2022.6166?guestAccessKey=76aee0a3-0ad8-44c4-b144-3cf2ca162e67&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=022723
About The Study: The results of this study of 1.65 million doses of BNT162b2 (Comirnaty [Pfizer-BioNTech]) vaccinations among adolescents in Ontario, Canada, suggest that there was variation in the reported incidence of myocarditis or pericarditis. However, the risk of these events after vaccination remains very rare and should be considered in relation to the benefits of COVID-19 vaccination.
Authors: Sarah E. Wilson, M.D., M.Sc., of Public Health Ontario in Toronto, is the corresponding author.
(doi:10.1001/jamapediatrics.2022.6166)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Assessment of Alcohol Exposure From Alcohol-Based Disinfectants Among Premature Infants in Neonatal Incubators
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Medical School Admissions Leaders’ Experiences With Barriers to and Advancements in Diversity, Equity, Inclusion
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Association of Frequent Aspirin Use With Ovarian Cancer Risk According to Genetic Susceptibility
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Association of Long-term Exposure to Particulate Air Pollution With Cardiovascular Events
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, FEBRUARY 24, 2023
Media advisory: The full study is linked to this news release.
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this study including 3.7 million adults in California, long-term fine particulate air pollution (PM2.5) exposure at moderate concentrations was associated with increased risks of heart attack, ischemic heart disease mortality and cardiovascular disease mortality. The findings add to the evidence that the current regulatory standard is not sufficiently protective.
Authors: Stacey E. Alexeeff, Ph.D., of the Kaiser Permanente Division of Research in Oakland, California, is the corresponding author.
(doi:10.1001/jamanetworkopen.2023.0561)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Comparing Transmission of COVID-19 in Nightlife, Household, Health Care Settings
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, FEBRUARY 24, 2023
Media advisory: The full study is linked to this news release.
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this case series study that analyzed 44,000 confirmed COVID-19 cases in Tokyo, cases identified in nightlife settings were associated with a higher likelihood of spreading COVID-19 than household and health care cases. Surveillance and interventions targeting nightlife settings should be prioritized to disrupt COVID-19 transmission, especially in the early stage of an epidemic.
Authors: Michihiko Yoshida, Ph.D., of the Minato Public Health Center in Tokyo, is the corresponding author.
(doi:10.1001/jamanetworkopen.2023.0589)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Exposure to Cancer Drugs Without Confirmed Benefit After FDA Accelerated Approval
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Myopia Prevalence in School-Aged Chinese Children After COVID-19 Home Confinement
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Detection of Omicron Variant of SARS-CoV-2 in Wastewater From Las Vegas Tourist Area
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Characterizing Moral Injury, Distress in Military Surgeons Deployed to Afghanistan and Iraq
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Mental Health in Veterans Before, During Pandemic
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Estimates, Projections of Global Economic Cost of 29 Cancers From 2020 to 2050
JAMA Oncology
EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, FEBRUARY 23, 2023
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaoncology/fullarticle/10.1001/jamaoncol.2022.7826?guestAccessKey=7b23f16f-8481-4de3-a0ff-10a755cb2857&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=022323
About The Study: In this decision analytical modeling study, the global economic cost of 29 cancers in 204 countries and territories from 2020 to 2050 was estimated to be $25.2 trillion (in international dollars at constant 2017 prices). The economic burden and the health burden were distributed unequally across countries, world regions, and country income groups. The results of this study suggest that global efforts to contain projected increases in the burden of cancers are warranted.
Authors: Simiao Chen, Sc.D., of the Heidelberg Institute of Global Health in Heidelberg, Germany, and Chen Wang, M.D., Ph.D., of the Chinese Academy of Medical Sciences and Peking Union Medical College in Beijing, are the corresponding authors.
(doi:10.1001/jamaoncol.2022.7826)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Differences in Ideal Cardiovascular Health Between Sexual Minority and Heterosexual Adults
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Trends in the Prevalence of Eczema Among Children by Age, Sex, Race, Ethnicity
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Association of Frailty With Risk of Suicide Attempt in Veterans Age 65 or Older
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Association of Routine Preoperative Frailty Assessment With 1-Year Postoperative Mortality
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Air Pollution and Emergency Department Visits During Infants’ First Year of Life
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Incidence of Aggressive End-of-Life Care Among Older Adults With Metastatic Cancer in Nursing Homes and Community Settings
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, FEBRUARY 22, 2023
Media advisory: The full study is linked to this news release.
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The results of this study suggest that despite increased emphasis to reduce aggressive end-of-life care in the past several decades, such care remains common among older persons with metastatic cancer and is slightly more prevalent among nursing home residents than their community-dwelling counterparts. Multilevel interventions to decrease aggressive end-of-life care should target the main factors associated with its prevalence, including hospital admissions in the last 30 days of life and in-hospital death.
Authors: Siran M. Koroukian, Ph.D., of the Case Western Reserve University School of Medicine in Cleveland, is the corresponding author.
(doi:10.1001/jamanetworkopen.2023.0394)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Association of Pandemic With Unsafe Living Situations, Intimate Partner Violence Among Pregnant Individuals
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, FEBRUARY 22, 2023
Media advisory: The full study is linked to this news release.
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: This study found an overall increase in unstable and/or unsafe living situations and intimate partner violence (IPV) between January 2019 and December 2020, with a temporary increase associated with the COVID-19 pandemic. It may be useful for emergency response plans to include IPV safeguards for future pandemics. These findings suggest the need for prenatal screening for unsafe and/or unstable living situations and IPV coupled with referral to appropriate support services and preventive interventions.
Authors: Lyndsay A. Avalos, Ph.D., M.P.H., of Kaiser Permanente Northern California in Oakland, is the corresponding author.
(doi:10.1001/jamanetworkopen.2023.0172)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Effect of Higher-Dose Ivermectin vs Placebo on Time to Sustained Recovery in Outpatients With COVID-19
JAMA
EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, FEBRUARY 20, 2023
Media advisory: The full study, editorial and editor’s note are linked to this news release.
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About The Study: Among 1,200 outpatients with mild to moderate COVID-19, treatment with ivermectin, with a maximum targeted dose of 600 µg/kg daily for six days, compared with placebo did not improve time to sustained recovery. These findings do not support the use of ivermectin in patients with mild to moderate COVID-19.
Authors: Susanna Naggie, M.D., M.H.S., of the Duke University School of Medicine in Durham, North Carolina, is the corresponding author.
(doi:10.1001/jama.2023.1650)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Using Haplotype-Based Artificial Intelligence to Evaluate SARS-CoV-2 Novel Variants, Mutations
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Association of Neighborhood-Level Household Income With Estrogen Receptor–Positive Breast Cancer Outcomes
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Rates of Spontaneous Abortion in Israel Before, During Pandemic
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Measures of Brain Connectivity, Cognition by Sex in Children
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, FEBRUARY 21, 2023
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2023.0157?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=022123
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The results of this neuroimaging study of 8,900 children ages 9 to 11 suggest that the observed sex differences in cognitive performance and brain connectivity likely reflect faster brain maturation in girls than boys. The findings are relevant to the future creation of brain developmental trajectory charts to monitor for deviations associated with impairments in cognition or behavior, including those due to psychiatric or neurological disorders.
Authors: Dardo Tomasi, Ph.D., of the National Institute on Alcohol Abuse and Alcoholism in Bethesda, Maryland, is the corresponding author.
(doi:10.1001/jamanetworkopen.2023.0157)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Accessibility of Public Health Websites for Information on COVID-19 Outpatient Treatments
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, FEBRUARY 21, 2023
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2023.0186?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=022123
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: This study found that COVID-19 treatment information on U.S. public health websites was poorly accessible, particularly for people with low literacy or limited English language proficiency, with worse accessibility for states and territories with Republican governors. The results suggest the need for national guidelines on accessibility and readability for public health websites.
Authors: Kevin A. Fiscella, M.D., M.P.H., of the University of Rochester Medical Center in Rochester, New York, is the corresponding author.
(doi:10.1001/jamanetworkopen.2023.0186)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Health Status, Health Care Access Among Lesbian, Gay, and Bisexual Adults in the US, 2013 to 2018
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Trends in Postmortem Neurodegenerative and Cerebrovascular Neuropathologies Over 25 Years
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Sensitivity and Specificity of the Modified Checklist for Autism in Toddlers
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Aspirin Discontinuation at 24 to 28 Weeks’ Gestation in Pregnancies at High Risk of Preterm Preeclampsia
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Dissemination of the Results of Pediatric Clinical Trials Funded by the National Institutes of Health
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Global Proportion of Disordered Eating in Children and Adolescents
JAMA Pediatrics
EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, FEBRUARY 20, 2023
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapediatrics/fullarticle/10.1001/jamapediatrics.2022.5848?guestAccessKey=a38cfc7b-1823-446c-a623-8be829a285ce&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=022023
About The Study: This systematic review and meta-analysis of 32 studies including 63,000 participants from 16 countries found that the overall proportion of children and adolescents with disordered eating was 22%. The proportion was further elevated among girls, as well as with increasing age and body mass index. These high figures are concerning from a public health perspective and highlight the need to implement strategies for preventing eating disorders.
Authors: Jose Francisco Lopez-Gil, Ph.D., of Universidad de Castilla-La Mancha in Cuenca, Spain, and Hector Gutierrez-Espinoza, Ph.D., of Universidad de las Americas in Quito, Ecuador, are the corresponding authors.
(doi:10.1001/jamapediatrics.2022.5848)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Disparities in Pediatric Medical and Childcare Disruption Due to COVID-19
JAMA Pediatrics
EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, FEBRUARY 20, 2023
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapediatrics/fullarticle/10.1001/jamapediatrics.2022.6130?guestAccessKey=2c5a1935-cbbf-41b7-af3a-d509b9299ead&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=022023
About The Study: Researchers found the highest rates of disruptions in childcare arrangements and missed or delayed preventive checkups among low socioeconomic status, Black and multiracial, and urban families during the COVID-19 pandemic. Future research should focus on the association of missing appointments with child health outcomes.
Authors: Kelsi Batioja, B.S., of Oklahoma State University Center for Health Sciences in Tulsa, is the corresponding author.
(doi:10.1001/jamapediatrics.2022.6130)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Evaluation of Maternal Infection During Pregnancy and Childhood Leukemia Among Offspring
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, FEBRUARY 20, 2023
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2023.0133?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=022023
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The results of this study of 2.2 million Danish children suggest that certain types of maternal infection during pregnancy were associated with an increased risk of childhood leukemia among offspring. If confirmed in future studies, the findings may have implications for understanding the etiology and developing preventive measures for childhood leukemia.
Authors: Jian-Rong He, D.Phil., of Guangzhou Medical University in Guangzhou, China, and Jiong Li, Ph.D., of Aarhus University in Aarhus, Denmark, are the corresponding authors.
(doi:10.1001/jamanetworkopen.2023.0133)
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History of Low Hourly Wage and All-Cause Mortality Among Middle-Age Workers
JAMA
EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, FEBRUARY 21, 2023
Media advisory: The full study is linked to this news release.
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About The Study: Sustained low-wage earning in midlife may be associated with elevated mortality risk and excess deaths, especially when experienced alongside unstable employment, according to the results of this study including 4,000 workers. If causal, the findings suggest that social and economic policies that improve the financial standing of low-wage workers (e.g., minimum wage laws) could improve mortality outcomes.
Authors: Katrina L. Kezios, Ph.D., of Columbia University in New York, is the corresponding author.
(doi:10.1001/jama.2023.0367)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Monoclonal Antibody for the Prevention of Respiratory Syncytial Virus in Infants and Children
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Antipsychotic Medication Use Among Older Adults Following Infection-Related Hospitalization
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Antibiotic Receipt During Outpatient Visits for COVID-19
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama-health-forum/fullarticle/10.1001/jamahealthforum.2022.5429?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=021723
About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
Mothers’ Experience With Health Insurance Coverage When Youngest Child Reaches 18 Years of Age
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About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
Association of Hypertensive Disorders of Pregnancy With Future Cardiovascular Disease
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, FEBRUARY 17, 2023
Media advisory: The full study is linked to this news release.
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The findings of this study provide genetic evidence supporting an association between hypertensive disorders of pregnancy and higher risk of coronary artery disease and stroke, which is only partially mediated by cardiometabolic factors. This supports classification of hypertensive disorders of pregnancy as risk factors for cardiovascular disease.
Authors: Fu Siong Ng, M.B.B.S., Ph.D., of Imperial College London, is the corresponding author.
(doi:10.1001/jamanetworkopen.2023.0034)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Assessment of Social Vulnerability in Pediatric Head and Neck Cancer Care and Prognosis
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, FEBRUARY 17, 2023
Media advisory: The full study is linked to this news release.
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this study of 37,000 patients with pediatric head and neck cancer, significant decreases in receipt of care and survival time were observed with increasing social determinants of health vulnerability.
Authors: Jeff C. Rastatter, M.D., M.S., of the Ann & Robert H. Lurie Children’s Hospital of Chicago, and David J. Fei-Zhang, B.A., of the Northwestern University Feinberg School of Medicine in Chicago, are the corresponding authors.
(doi:10.1001/jamanetworkopen.2023.0016)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Relaunching JAMA Express
JAMA
EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, FEBRUARY 16, 2023
Media advisory: The full editorial is linked to this news release.
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About The Editorial: JAMA is relaunching JAMA Express, a pathway in which manuscripts receive expedited review and processing with the goal of online publication of accepted work within four weeks of submission.
Authors: Kirsten Bibbins-Domingo, Ph.D., M.D., M.A.S., Editor in Chief, JAMA and the JAMA Network, Chicago, is the corresponding author.
(doi:10.1001/jama.2023.2449)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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States’ Methods for Capturing and Reporting Local Responses to Suspected Nonfatal Drug Overdoses
JAMA
EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, FEBRUARY 16, 2023
Media advisory: The full study is linked to this news release.
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About The Study: The findings of this study indicate that not all states comprehensively report nonfatal drug overdoses and current estimates may be undercounted given that not all people who experience an overdose connect with medical services or community programs.
Authors: Christian Johnson, M.P.H., of the White House Office of National Drug Control Policy in Washington, D.C., is the corresponding author.
(doi:10.1001/jama.2023.0169)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Racial Disparity in Survival From Early-Stage, Hormone-Dependent Breast Cancer
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Diagnostic Accuracy of Amsler Grid Test for Detecting Neovascular Age-Related Macular Degeneration
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Severe Maternal Morbidity by Immigration Status in Low-Income Neighborhoods in Ontario
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Vaccination Intention Following Receipt of Vaccine Information Through Interactive Simulation vs Text
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Effects of an Immersive Virtual Reality Intervention on Pain, Anxiety Among Pediatric Patients Undergoing a Blood Draw
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, FEBRUARY 16, 2023
Media advisory: The full study is linked to this news release.
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this randomized clinical trial, integrating procedural information and distraction in an immersive virtual reality (IVR) intervention for pediatric patients undergoing a blood draw significantly improved pain and anxiety in the IVR group compared with the control group. The results shed light on the global trends of research on IVR and its clinical development as an intervention for other painful and stressful medical procedures.
Authors: Cho Lee Wong, R.N., Ph.D., of the Chinese University of Hong Kong, is the corresponding author.
(doi:10.1001/jamanetworkopen.2023.0001)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Association of Expanded Child Tax Credit Payments With Child Abuse and Neglect Emergency Department Visits
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, FEBRUARY 16, 2023
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2022.55639?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=021623
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: This study examined the association of the 2021 expanded child tax credit (CTC) advance payments with child abuse and neglect and found immediate reductions in child abuse and neglect-related emergency department visits in the days following disbursement of the CTC payments. These results are important for discussions of making the temporary expansion of the CTC permanent and are applicable to income support policies more broadly.
Authors: Lindsey Rose Bullinger, Ph.D., of the Georgia Institute of Technology in Atlanta, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.55639)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Association of Accelerometer-Measured Physical Activity Level With Risks of Hospitalization for Common Health Conditions
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, FEBRUARY 16, 2023
Media advisory: The full study is linked to this news release.
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this study using accelerometer data from 81,000 UK Biobank participants, those with higher physical activity levels had lower risks of hospitalization across a broad range of health conditions. These findings suggest that aiming to increase moderate to vigorous physical activity by 20 minutes per day may be a useful nonpharmaceutical intervention to reduce health care burdens and improve quality of life.
Authors: Eleanor L. Watts, D.Phil., of the National Cancer Institute in Rockville, Maryland, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.56186)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Association of Cardiovascular Health With Risk of Clinically Relevant Depressive Symptoms
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Hospitalization Associated With Comorbid Psychiatric, Substance Use Disorders Among Adults With COVID-19
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Performance of a Prediction Model of Suicide Attempts Across Race and Ethnicity
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Prediction of Suicide Attempts, Suicide-Related Events Among Adolescents Seen in Emergency Departments
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Trends in Screen Time Use Among Children During Pandemic
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, FEBRUARY 15, 2023
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2022.56157?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=021523
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The findings of this study of 228 children ages 4 to 12 suggest that screen time among children increased during the COVID-19 pandemic and remained elevated even after many public health precautions were lifted. The long-term association of increased screen time during the COVID-19 pandemic with children’s health needs to be determined.
Authors: Monique M. Hedderson, Ph.D., of the Kaiser Permanente Northern California Division of Research in Oakland, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.56157)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Association of Long COVID Symptoms and Employment Status
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, FEBRUARY 15, 2023
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2022.56152?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=021523
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: Among 15,000 individuals with prior COVID-19 infection, those with post–COVID-19 condition (PCC), also known as long COVID, were less likely to be employed full-time and more likely to be unemployed. The presence of cognitive symptoms was associated with diminished likelihood of working full time. These results underscore the importance of developing strategies to treat and manage PCC symptoms.
Authors: Roy H. Perlis, M.D., M.Sc., of Massachusetts General Hospital in Boston, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.56152)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Early vs Deferred Non–Messenger RNA COVID-19 Vaccination Among Chinese Patients With Inactive Uveitis
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Emergency Department, Hospital Utilization Among Older Adults Before, After Identification of Elder Mistreatment
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