Incidence, Prevalence of Diagnosed Vitiligo According to Race, Ethnicity, Age, and Sex

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Suicide Ideation, Plan, and Attempt by Gender, Sexual Orientation, Race, Ethnicity, and Rurality

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Association Between Markers of Structural Racism and Mass Shooting Events in Major US Cities

JAMA Surgery

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, JULY 19, 2023

Media advisory: The full study and commentary are linked to this news release.

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About The Study: This study found that major U.S. cities with higher populations of Black individuals are more likely to be affected by mass shooting events, suggesting that structural racism may have a role in their incidence. Public health initiatives aiming to prevent mass shooting events should target factors associated with structural racism to address gun violence.

Authors: Michael Ghio, M.D., of Tulane University in New Orleans, is the corresponding author.

 

(doi:10.1001/jamasurg.2023.2846)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Trends, Seasonality of Emergency Department Visits, Hospitalizations for Suicidality Among Children and Adolescents

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, JULY 19, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: The findings of this study of 73,000 emergency department visits and hospitalizations for suicidality indicated the presence of seasonal patterns and an observed unexpected decrease in suicidality among children and adolescents after COVID-19–related school closures in March 2020, which suggest a potential association between suicidality and the school calendar. 

Authors: Scott D. Lane, Ph.D., of the University of Texas Health Science Center at Houston, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.24183)

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Prenatal Health Care Outcomes Before, During Pandemic

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, JULY 18, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: The findings of this study of 151,000 pregnant individuals suggest that a multimodal prenatal health care model combining in-office and telemedicine visits performed adequately compared with in-office only prenatal health care, supporting its continued use after the pandemic. 

Authors: Assiamira Ferrara, M.D., Ph.D., of Kaiser Permanente Northern California in Oakland, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.24011)

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Sleep Architecture, Obstructive Sleep Apnea, and Cognitive Function in Adults

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, JULY 18, 2023

Media advisory: The full study is linked to this news release. This study is being released to coincide with presentation at the Alzheimer’s Association International Conference.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: This study found that better sleep consolidation and the absence of obstructive sleep apnea were associated with better global cognition over five years of follow-up. These findings suggest that the role of interventions to improve sleep for maintaining cognitive function requires investigation. 

Authors: Matthew P. Pase, Ph.D., of Monash University in Melbourne, Australia, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.25152)

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Donanemab in Early Symptomatic Alzheimer Disease

JAMA

EMBARGOED FOR RELEASE: 10:15 A.M. (ET), MONDAY, JULY 17, 2023

Media advisory: The full study and editorials are linked to this news release. This study is being released to coincide with presentation at the Alzheimer’s Association International Conference.

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About The Study: In this phase 3 randomized clinical trial that included 1,736 participants with early symptomatic Alzheimer disease and amyloid and tau pathology, donanemab, an antibody designed to clear brain amyloid plaque, significantly slowed clinical progression at 76 weeks in those with low/medium tau and in the combined low/medium and high tau pathology population.

Authors: John R. Sims, M.D., of Eli Lilly and Company in Indianapolis, is the corresponding author.

 

(doi:10.1001/jama.2023.13239)

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Chatbot vs Medical Student Performance on Free-Response Clinical Reasoning Examinations

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Comparison of History of Present Illness Summaries Generated by a Chatbot and Senior Internal Medicine Residents

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, JULY 17, 2023

Media advisory: The full study and editor’s note are linked to this news release.

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About The Study: History of present illnesses generated by a chatbot or written by senior internal medicine residents were graded similarly by internal medicine attending physicians. These findings underscore the potential of chatbots to aid clinicians with medical documentation. 

Authors: Ashwin Nayak, M.D., M.S., of Stanford University in Stanford, California, is the corresponding author.

 

(doi:10.1001/jamainternmed.2023.2561)

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Excess Mortality With Alzheimer Disease and Related Dementias as an Underlying or Contributing Cause During Pandemic

JAMA Neurology

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, JULY 17, 2023

Media advisory: The full study is linked to this news release.

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About The Study: This study found that large increases in mortality with Alzheimer disease and related dementias as an underlying or contributing cause of death occurred in COVID-19 pandemic year 1 but were largely mitigated in pandemic year 2. The most pronounced declines were observed for deaths in nursing home/long-term care settings. Conversely, excess deaths at home and in medical facilities remained high in year 2. 

Authors: M. Maria Glymour, Sc.D., of the Boston University School of Public Health in Boston, is the corresponding author.

 

(doi:10.1001/jamaneurol.2023.2226)

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Heading Frequency and Risk of Cognitive Impairment in Retired Male Professional Soccer Players

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, JULY 17, 2023

Media advisory: The full study and commentary are linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: The findings of this study suggest that repetitive heading during a professional soccer career is associated with an increased risk of cognitive impairment in later life. Further study is needed to establish the upper threshold for heading frequency to mitigate this risk. 

Authors: Weiya Zhang, Ph.D., of the University of Nottingham in Nottingham, United Kingdom, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.23822)

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Accelerometer-Derived ‘Weekend Warrior’ Physical Activity and Incident Cardiovascular Disease

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, JULY 18, 2023

Media advisory: The full study and Viewpoint are linked to this news release.

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About The Study: In an analysis of 89,000 individuals providing a week of accelerometer-based physical activity data, a weekend warrior pattern of physical activity (i.e., most moderate to vigorous physical activity achieved over 1-2 days) was associated with similarly lower risks of incident atrial fibrillation, heart attack, heart failure, and stroke compared with more evenly distributed physical activity.

Authors: Patrick T. Ellinor, M.D., Ph.D., of Massachusetts General Hospital in Boston, is the corresponding author.

 

(doi:10.1001/jama.2023.10875)

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USPSTF Recommendation Statement on Screening for Lipid Disorders in Children and Adolescents

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, JULY 18, 2023

Media advisory: To contact the U.S. Preventive Services Task Force, email the Media Coordinator at Newsroom@USPSTF.net or call 301-951-9203. The full report and related articles are linked to this news release.

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Bottom Line: The U.S. Preventive Services Task Force (USPSTF) concludes that the current evidence is insufficient to assess the balance of benefits and harms of screening for lipid disorders in children and adolescents 20 years or younger. Familial hypercholesterolemia and multifactorial dyslipidemia are two conditions that cause abnormally high lipid levels in children, which can lead to premature cardiovascular events (e.g., heart attack and stroke) and death in adulthood. The USPSTF routinely makes recommendations about the effectiveness of preventive care services and this recommendation statement is consistent with its 2016 recommendation.

 

(doi:10.1001/jama.2023.11330)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.

Note: More information about the U.S. Preventive Services Task Force, its process, and its recommendations can be found on the newsroom page of its website.

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Spending on Phased Clinical Development of Approved Drugs by the NIH Compared With Industry

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About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

Changes in Hospital Financial Performance During the COVID-19 Public Health Emergency

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About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

Lifestyle Enrichment in Later Life and Its Association With Dementia Risk

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, JULY 14, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: In this study of 10,000 older individuals in Australia, more frequent participation in adult literacy activities (taking education classes, using a computer, and writing letters or journals) and in active mental activities (playing games, cards, or chess and doing crosswords or puzzles) was associated with reduced dementia risk over 10 years. However, social outings and interactions were not associated with dementia risk. 

Authors: Joanne Ryan, Ph.D., of Monash University in Melbourne, Australia, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.23690)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Associations Between Neighborhood-Level Racial Residential Segregation, Socioeconomic Factors, and Life Expectancy

JAMA Health Forum

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, JULY 14, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

 

About The Study: This nationwide cross-sectional study demonstrated that residing in a highly segregated neighborhood was associated with a statistically significantly lower life expectancy by four years, which was partially mediated by neighborhood-level socioeconomic factors. These findings help to quantify the contribution of residential segregation as a key structural driver of racial inequities. 

Authors: Sadiya S. Khan, M.D., M.Sc., of the Northwestern University Feinberg School of Medicine in Chicago, is the corresponding author.

 

(doi:10.1001/jamahealthforum.2023.1805)

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Effects of Meditation Training and Non-Native Language Training on Cognition in Older Adults

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, JULY 14, 2023

Media advisory: The full study is linked to this news release. This study is being released to coincide with presentation at the Alzheimer’s Association International Conference.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: In this secondary analysis of an 18-month randomized trial that included 135 older adults, meditation and non-native language training did not confer salutary cognitive effects. Although further analyses are needed to explore the effects of these interventions on other relevant outcomes related to aging and well-being, these findings did not support the use of these interventions for enhancing cognition in cognitively healthy older adults. 

Authors: Natalie L. Marchant, Ph.D., of University College London, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.17848)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Low-Dose Atropine Eye Drops vs Placebo for Myopia Control

JAMA Ophthalmology

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, JULY 13, 2023

Media advisory: The full study and commentary are linked to this news release.

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About The Study: In this randomized clinical trial of school-age children in the U.S. with low to moderate myopia (nearsightedness), atropine, 0.01%, eye drops administered nightly when compared with placebo did not slow myopia progression or axial elongation. These results do not support use of atropine, 0.01%, eye drops to slow myopia progression or axial elongation in U.S. children.

Authors: Michael X. Repka, M.D., M.B.A., of the Wilmer Eye Institute in Baltimore, is the corresponding author.

 

(doi:10.1001/jamaophthalmol.2023.2855)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Performance of an Upgraded AI Chatbot for Ophthalmic Knowledge Assessment

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Objectively Measured Visual Impairment and Dementia Prevalence in Older Adults

JAMA Ophthalmology

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, JULY 13, 2023

Media advisory: The full study and commentary are linked to this news release.

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About The Study: In this survey study, all types of objectively measured visual impairment were associated with a higher dementia prevalence. As most visual impairment is preventable, prioritizing vision health may be important for optimizing cognitive function.

Authors: Joshua R. Ehrlich, M.D., M.P.H., of the University of Michigan in Ann Arbor, is the corresponding author.

 

(doi:10.1001/jamaophthalmol.2023.2854)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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COVID-19 Severity and Waning Immunity After up to 4 mRNA Vaccine Doses in Patients With Cancer

JAMA Oncology

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, JULY 13, 2023

Media advisory: The full study is linked to this news release.

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About The Study: This study provides evidence of the clinical effectiveness of mRNA-based vaccines against COVID-19 in patients with cancer. Longevity of immunity in preventing severe COVID-19 outcomes in actively treated patients with cancer, cancer survivors, and matched controls was observed at least five months after the third or fourth dose. 

Authors: Raghav Sundar, M.B.B.S., Ph.D., of the National University Health System in Singapore, and Kelvin Bryan Tan, Ph.D., of the Ministry of Health in Singapore, are the corresponding authors. 

 

(doi:10.1001/jamaoncol.2023.2271)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Feasibility, Utility of Prediction Models for Breast Cancer–Related Lymphedema Incorporating Racial Differences in Disease Incidence

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County-Level Income Inequality, Social Mobility, and Deaths of Despair in the US

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, JULY 12, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: This study found that the joint exposure of unequal income distribution and lack of social mobility was associated with additional risks for deaths of despair (deaths from suicide, drug overdose, and alcohol-related liver disease), suggesting that addressing the underlying social and economic conditions is crucial in responding to the epidemic of deaths of despair. 

Authors: Chun-Tung Kuo, Ph.D., of National Taiwan University in Taipei, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.23030)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Trends in Acute Care Use for Mental Health Conditions Among Youth During Pandemic

JAMA Psychiatry

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, JULY 12, 2023

Media advisory: The full study and editorial are linked to this news release.

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About The Study: Into the second year of the pandemic, mental health emergency department visits increased notably among adolescent females, and there was an increase in prolonged boarding (waiting in an emergency department or medical inpatient unit) of youth awaiting inpatient psychiatric care. Interventions are needed to increase inpatient child psychiatry capacity and reduce strain on the acute mental health care system.

Authors: Haiden A. Huskamp, Ph.D., of Harvard Medical School in Boston, is the corresponding author.

 

(10.1001/jamapsychiatry.2023.2195)

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Abatacept, Cenicriviroc, or Infliximab for Treatment of Adults Hospitalized With COVID-19 Pneumonia

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, JULY 10, 2023

Media advisory: The full study and editorial are linked to this news release.

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About The Study: This randomized clinical trial found that treatment with abatacept, cenicriviroc, or infliximab showed no significant difference of time to recovery compared with placebo for patients hospitalized with COVID-19 pneumonia.

Authors: William G. Powderly, M.D., of the Washington University School of Medicine in St. Louis, is the corresponding author.

 

(doi:10.1001/jama.2023.11043)

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Core Biopsy and Extranodal Extension in Surgically Treated HPV-Associated Oropharyngeal Squamous Cell Carcinoma

This study is being released to coincide with presentation at the AHNS 11th International Conference on Head and Neck Cancer.

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Association Between Historical Neighborhood Redlining and Cardiovascular Outcomes Among Veterans

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, JULY 11, 2023

Media advisory: The full study and commentary are linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: In this cohort study of U.S. veterans, the findings suggest that those with atherosclerotic cardiovascular disease who reside in historically redlined neighborhoods continue to have a higher prevalence of traditional cardiovascular risk factors and higher cardiovascular risk. Even close to a century after this practice was discontinued, redlining appears to still be adversely associated with adverse cardiovascular events. 

Authors: Sadeer Al-Kindi, M.D., of University Hospitals in Cleveland, and Salil V. Deo, M.D., of Louis Stokes Veteran Affairs Hospital in Cleveland, are the corresponding authors. 

 

(doi:10.1001/jamanetworkopen.2023.22727)

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Association of Racial Discrimination With Obesity in Children and Adolescents

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, JULY 11, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: The findings of this study suggest that personally mediated racial discrimination may be a risk factor for developing obesity in children and adolescents, above and beyond socioeconomic status. The results highlight the need for a multifaceted approach to address racial discrimination and its impact on the health of children and adolescents.

Authors: Adolfo G. Cuevas, Ph.D., of the New York University School of Global Public Health in New York, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.22839)

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Key Points for Clinicians About the SEER Oral Cancer Survival Calculator

JAMA Otolaryngology–Head & Neck Surgery

EMBARGOED FOR RELEASE: 4 P.M. (ET), MONDAY, JULY 10, 2023

Media advisory: The full article and commentary are linked to this news release. This article is being released to coincide with presentation at the AHNS 11th International Conference on Head and Neck Cancer.

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About The Article: This article describes the Surveillance, Epidemiology, and End Results Oral Cancer Survival Calculator, which is designed to provide patient-specific survival estimates based on the severity of an index cancer as well as the competing risk of death of other comorbid ailments. 

Authors: Louise Davies, M.D., M.S., of the Department of Veterans Affairs Medical Center in White River Junction, Vermont, is the corresponding author. 

 

(doi:10.1001/jamaoto.2023.1977)

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Performance of Liquid Biopsy for Diagnosis and Surveillance of HPV-Associated Oropharyngeal Cancer

This study is being released to coincide with presentation at the AHNS 11th International Conference on Head and Neck Cancer.

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Personalized Oral Cancer Survival Calculator to Estimate Risk of Death From Oral Cancer or Other Causes

JAMA Otolaryngology–Head & Neck Surgery

EMBARGOED FOR RELEASE: 4 P.M. (ET), MONDAY, JULY 10, 2023

Media advisory: The full study and commentary are linked to this news release. This study is being released to coincide with presentation at the AHNS 11th International Conference on Head and Neck Cancer.

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About The Study: The models developed for the Surveillance, Epidemiology, and End Results Oral Cancer Survival Calculator demonstrate that survival estimates that exclude the effects of coexisting conditions can lead to underestimates or overestimates of survival. 

Authors: Louise Davies, M.D., M.S., of the Department of Veterans Affairs Medical Center in White River Junction, Vermont, is the corresponding author. 

 

(doi:10.1001/jamaoto.2023.1975)

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Oncologic Significance of Therapeutic Delays in Patients With Oral Cavity Cancer

This study is being released to coincide with presentation at the AHNS 11th International Conference on Head and Neck Cancer.

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Surgery vs Chemoradiation Outcomes in Patients With T1-T2 Oropharyngeal Squamous Cell Carcinoma

This study is being released to coincide with presentation at the AHNS 11th International Conference on Head and Neck Cancer.

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Racial, Ethnic Differences in Factors Associated With Delayed or Missed Pediatric Preventive Care Due to the Pandemic

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, JULY 10, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: In this cross-sectional study, more than one-fourth of children had delayed or missed preventive care due to the COVID-19 pandemic. These findings may guide targeted interventions to enhance timely pediatric preventive care among different racial and ethnic groups. 

Authors: Maya Tabet, Ph.D., M.S., of the University of Health Sciences and Pharmacy in St. Louis, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.22588)

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Prevalence, Trends in Diagnosed Learning Disability Among US Children and Adolescents

JAMA Pediatrics

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, JULY 10, 2023

Media advisory: The full study is linked to this news release.

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About The Study: Based on U.S. nationally representative data, the estimated learning disability prevalence was 8.83% among children and adolescents ages 6 to 17 from 1997 to 2021, which was slightly higher than that from a previous National Health Interview Survey study from 2009 to 2017 (7.74%). These data indicate that learning disability is a common chronic condition among U.S. children, affecting about 9 in 100 overall. In this population-based study, no significant annual change was found. 

Authors: Wenhan Yang, M.D., Ph.D., and Qingsong Chen, M.D., Ph.D., of Guangdong Pharmaceutical University, Guangzhou, Guangdong Province, China, are the corresponding authors.

 

(doi:10.1001/jamapediatrics.2023.2117)

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Association Between Pandemic and Early Childhood Development

JAMA Pediatrics

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, JULY 10, 2023

Media advisory: The full study is linked to this news release.

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About The Study: The findings of this study showed an association between exposure to the COVID-19 pandemic and delayed childhood development at age 5. Variations in development widened during the pandemic regardless of age. It is important to identify children with developmental delays associated with the pandemic and provide them with support for learning, socialization, physical and mental health, and family support. 

Authors: Koryu Sato, M.P.H., of Kyoto University in Kyoto, Japan, is the corresponding author.

 

(doi:10.1001/jamapediatrics.2023.2096)

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Physician and Nurse Well-Being and Preferred Interventions to Address Burnout in Hospital Practice

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama-health-forum/fullarticle/10.1001/jamahealthforum.2023.1809?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=070723

About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

Understanding How Post–COVID-19 Condition Affects Adults and Health Care Systems

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About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

Evaluation of Population-Level Tobacco Control Interventions and Health Outcomes

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, JULY 7, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: In this systematic review and meta-analysis, smoke-free legislation was associated with significant reductions in morbidity and mortality related to cardiovascular disease, respiratory system disease, and perinatal outcomes. These findings support the need to accelerate the implementation of smoke-free laws to protect populations against smoking-related harm. 

Authors: Ryota Nakamura, Ph.D., of Hitotsubashi University in Tokyo, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.22341)

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Trends in Opioid Toxicity–Related Deaths in the US Before, After the Start of the Pandemic

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, JULY 7, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: Deaths due to opioid toxicity increased substantially during the COVID-19 pandemic. By 2021, 1 of every 22 deaths in the U.S. was attributable to unintentional opioid toxicity, underscoring the urgent need to support people at risk of substance-related harm, particularly men, younger adults, and adolescents. 

Authors: Tara Gomes, Ph.D., of the University of Toronto, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.22303)

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Gender Differences in Fears Related to Low-Risk Papillary Thyroid Cancer and Its Treatment

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Hearing Loss and Fatigue in Middle-Age and Older Adults

JAMA Otolaryngology–Head & Neck Surgery

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, JULY 6, 2023

Media advisory: The full study is linked to this news release.

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About The Study: Hearing loss was cross-sectionally associated with higher frequency of fatigue after adjustment for demographics, lifestyle factors, and comorbidities in this nationally representative sample of middle-age and older adults. Future studies with fatigue assessments capturing its multidimensionality are needed to understand how hearing loss might contribute to physical and mental fatigue differentially and clarify how hearing loss may be associated with downstream outcomes like physical impairment through fatigue. 

Authors: Nicholas S. Reed, Au.D., of the Johns Hopkins Bloomberg School of Public Health in Baltimore, is the corresponding author. 

 

(doi:10.1001/jamaoto.2023.1328)

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Health Outcomes, Cost-effectiveness of Monoclonal SARS-CoV-2 Antibodies as Pre-exposure Prophylaxis

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, JULY 6, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: This decision analytic model showed that within the context of a high SARS-CoV-2 probability, monoclonal antibodies pre-exposure prophylaxis (mAbs PrEP) provision was cost-saving when provided to individuals at increased risk of severe COVID-19 if drug prices decrease to $275 and effectiveness is 75% or higher. When newer mAbs PrEP combinations become available, guidance on implementation should be formulated ensuring a fast rollout. Nevertheless, advocacy for mAbs PrEP use and critical discussion on drug prices are necessary to ensuring cost-effectiveness for different epidemic settings. 

Authors: Stephanie Popping, M.D., Ph.D., of the University of Amsterdam, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.21985)

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Association Between Stimulant Treatment and Substance Use Through Adolescence Into Early Adulthood

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Cannabis Use Disorder and Perioperative Complications

JAMA Surgery

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, JULY 5, 2023

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamasurgery/fullarticle/10.1001/jamasurg.2023.2403?guestAccessKey=aa65fb77-bc60-4168-a326-908854d99166&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=070523

 

About The Study: Cannabis use disorder was associated with a modest increased risk of perioperative morbidity and mortality after major elective, inpatient, noncardiac surgery. In the context of increasing cannabis use rates, these findings support preoperative screening for cannabis use disorder as a component of perioperative risk stratification. However, further research is needed to quantify the perioperative impact of cannabis use by route and dosage and to inform recommendations for preoperative cannabis cessation.

Authors: Paul P. Potnuru, M.D., of the University of Texas Health Science Center at Houston, is the corresponding author.

 

(doi:10.1001/jamasurg.2023.2403)

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Internet Searches for Self-Managed Abortion After Roe v Wade Overturned

JAMA Surgery

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, JULY 5, 2023

Media advisory: The full study is linked to this news release.

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About The Study: This study used Google Trends data to estimate public interest in self-managed abortions and whether this interest differs depending on the legality of abortion in a state.

Authors: Sean D. Young, Ph.D., of the University of California, Irvine, is the corresponding author.

 

(doi:10.1001/jamasurg.2023.2410)

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BMI and Associated Medical Expenditures Among Privately Insured Individuals Ages 2 to 19

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Associations of Food Insecurity and Memory Function Among Middle to Older–Age Adults

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, JULY 3, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: Food insecurity was associated with slightly faster memory decline among middle to older–age individuals, suggesting possible long-term negative cognitive function outcomes associated with exposure to food insecurity in older age. 

Authors: Adina Zeki Al Hazzouri, Ph.D., of Columbia University in New York, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.21474)

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Trends in Mortality From Poisonings, Firearms, and All Other Injuries by Intent

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, JULY 3, 2023

Media advisory: The full study and commentary are linked to this news release.

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About The Study: The results of this study suggest that from 1999 to 2020, death rates due to poisonings, firearms, and all other injuries increased substantially in the U.S. The rapid increase in deaths due to unintentional poisonings and firearm homicides is a national emergency that requires urgent public health interventions at the local and national levels. 

Authors: Wayne R. Lawrence, Dr.P.H., of the National Institutes of Health in Bethesda, Maryland, is the corresponding author.

 

(doi:10.1001/jamainternmed.2023.2509)

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Global, Regional, and National Epidemiology of Diabetes in Children

JAMA Pediatrics

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, JULY 3, 2023

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About The Study: Childhood diabetes is an increasing global health challenge with rising incidence. Results of this study suggest that despite the global decline in deaths and disability-adjusted life-years (DALYs), the number of deaths and DALYs remains high among children with diabetes, especially in low Sociodemographic Index regions. Improved understanding of the epidemiology of diabetes in children may facilitate prevention and control. 

Authors: Xiaodong Sun, M.D., Ph.D., and Ningning Hou, M.D., of the Affiliated Hospital of Weifang Medical University in Weifang, China, are the corresponding authors.

 

(doi:10.1001/jamapediatrics.2023.2029)

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Trends in State-Level Maternal Mortality by Racial and Ethnic Group

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, JULY 3, 2023

Media advisory: The full study is linked to this news release.

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About The Study: While maternal mortality remains unacceptably high among all racial and ethnic groups in the U.S., American Indian and Alaska Native and Black individuals are at increased risk, particularly in several states where these inequities had not been previously highlighted. Maternal mortality persists as a source of worsening disparities in many U.S. states and prevention efforts during this study period (1999 to 2019) appear to have had a limited impact in addressing this health crisis.

Authors: Gregory A. Roth, M.D., M.P.H., of the University of Washington in Seattle, is the corresponding author.

 

(doi:10.1001/jama.2023.9043)

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Association of Population Well-Being With Cardiovascular Outcomes

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, JULY 5, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: Assessing the association of well-being and cardiovascular outcomes, higher well-being, a measurable, modifiable, and meaningful outcome, was associated with lower cardiovascular disease mortality, even after controlling for structural and cardiovascular-related population health factors, indicating that well-being may be a focus for advancing cardiovascular health.

Authors: Erica S. Spatz, M.D., M.H.S., of the Yale School of Medicine in New Haven, Connecticut, is the corresponding author.

 

(doi: 10.1001/jamanetworkopen.2023.21740)

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Perspectives About Racism and Patient-Clinician Communication Among Black Adults With Serious Illness

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, JULY 5, 2023

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2023.21746?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=070523

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: This study found that Black patients’ experiences with racism, specifically epistemic injustice, were associated with their perspectives on medical care and decision making during serious illness and end of life. These findings suggest that race-conscious, intersectional approaches may be needed to improve patient-clinician communication and support Black patients with serious illness to alleviate the distress and trauma of racism as these patients near the end of life.

Authors: Crystal E. Brown, M.D., M.A., of the University of Washington in Seattle, is the corresponding author.

 

(doi: 10.1001/jamanetworkopen.2023.21746)

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Seasonality in RSV Hospitalizations and Immunoprophylaxis

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About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

Incidence of Diabetes in Children and Adolescents During the Pandemic

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, JUNE 30, 2023

Media advisory: The full study and commentary are linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: Incidence rates of type 1 diabetes and diabetic ketoacidosis at diabetes onset in children and adolescents were higher after the start of the COVID-19 pandemic than before the pandemic. Increased resources and support may be needed for the growing number of children and adolescents with diabetes. Future studies are needed to assess whether this trend persists and may help elucidate possible underlying mechanisms to explain temporal changes. 

Authors: Rayzel Shulman, M.D., Ph.D., of the SickKids Research Institute in Toronto, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.21281)

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Association of Preoperative High-Intensity Interval Training With Cardiorespiratory Fitness, Postoperative Outcomes Among Adults Undergoing Major Surgery

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, JUNE 30, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: The results of this systematic review and meta-analysis of 12 studies including 832 patients suggest that preoperative high-intensity interval training may improve cardiorespiratory fitness and reduce postoperative complications. These findings support including high-intensity interval training in pre-habilitation programs before major surgery. 

Authors: John C. Woodfield, Ph.D., of the University of Otago in Dunedin, New Zealand, is the corresponding author.

  

(doi:10.1001/jamanetworkopen.2023.20527)

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Cochlear Implantation and Educational and Quality-of-Life Outcomes in Adolescence

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