Estimates, Projections of Global Economic Cost of 29 Cancers From 2020 to 2050

JAMA Oncology

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, FEBRUARY 23, 2023

Media advisory: The full study is linked to this news release.

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About The Study: In this decision analytical modeling study, the global economic cost of 29 cancers in 204 countries and territories from 2020 to 2050 was estimated to be $25.2 trillion (in international dollars at constant 2017 prices). The economic burden and the health burden were distributed unequally across countries, world regions, and country income groups. The results of this study suggest that global efforts to contain projected increases in the burden of cancers are warranted. 

Authors: Simiao Chen, Sc.D., of the Heidelberg Institute of Global Health in Heidelberg, Germany, and Chen Wang, M.D., Ph.D., of the Chinese Academy of Medical Sciences and Peking Union Medical College in Beijing, are the corresponding authors. 

 

(doi:10.1001/jamaoncol.2022.7826)

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Differences in Ideal Cardiovascular Health Between Sexual Minority and Heterosexual Adults

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Trends in the Prevalence of Eczema Among Children by Age, Sex, Race, Ethnicity

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Association of Frailty With Risk of Suicide Attempt in Veterans Age 65 or Older

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Association of Routine Preoperative Frailty Assessment With 1-Year Postoperative Mortality

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Incidence of Aggressive End-of-Life Care Among Older Adults With Metastatic Cancer in Nursing Homes and Community Settings

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, FEBRUARY 22, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: The results of this study suggest that despite increased emphasis to reduce aggressive end-of-life care in the past several decades, such care remains common among older persons with metastatic cancer and is slightly more prevalent among nursing home residents than their community-dwelling counterparts. Multilevel interventions to decrease aggressive end-of-life care should target the main factors associated with its prevalence, including hospital admissions in the last 30 days of life and in-hospital death.  

Authors: Siran M. Koroukian, Ph.D., of the Case Western Reserve University School of Medicine in Cleveland, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.0394)

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Association of Pandemic With Unsafe Living Situations, Intimate Partner Violence Among Pregnant Individuals

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, FEBRUARY 22, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: This study found an overall increase in unstable and/or unsafe living situations and intimate partner violence (IPV) between January 2019 and December 2020, with a temporary increase associated with the COVID-19 pandemic. It may be useful for emergency response plans to include IPV safeguards for future pandemics. These findings suggest the need for prenatal screening for unsafe and/or unstable living situations and IPV coupled with referral to appropriate support services and preventive interventions. 

Authors: Lyndsay A. Avalos, Ph.D., M.P.H., of Kaiser Permanente Northern California in Oakland, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.0172)

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Effect of Higher-Dose Ivermectin vs Placebo on Time to Sustained Recovery in Outpatients With COVID-19

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, FEBRUARY 20, 2023

Media advisory: The full study, editorial and editor’s note are linked to this news release.

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About The Study: Among 1,200 outpatients with mild to moderate COVID-19, treatment with ivermectin, with a maximum targeted dose of 600 µg/kg daily for six days, compared with placebo did not improve time to sustained recovery. These findings do not support the use of ivermectin in patients with mild to moderate COVID-19.  

Authors: Susanna Naggie, M.D., M.H.S., of the Duke University School of Medicine in Durham, North Carolina, is the corresponding author.

 

(doi:10.1001/jama.2023.1650)

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Measures of Brain Connectivity, Cognition by Sex in Children

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, FEBRUARY 21, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: The results of this neuroimaging study of 8,900 children ages 9 to 11 suggest that the observed sex differences in cognitive performance and brain connectivity likely reflect faster brain maturation in girls than boys. The findings are relevant to the future creation of brain developmental trajectory charts to monitor for deviations associated with impairments in cognition or behavior, including those due to psychiatric or neurological disorders. 

Authors: Dardo Tomasi, Ph.D., of the National Institute on Alcohol Abuse and Alcoholism in Bethesda, Maryland, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.0157)

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Accessibility of Public Health Websites for Information on COVID-19 Outpatient Treatments

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, FEBRUARY 21, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: This study found that COVID-19 treatment information on U.S. public health websites was poorly accessible, particularly for people with low literacy or limited English language proficiency, with worse accessibility for states and territories with Republican governors. The results suggest the need for national guidelines on accessibility and readability for public health websites. 

Authors: Kevin A. Fiscella, M.D., M.P.H., of the University of Rochester Medical Center in Rochester, New York, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.0186)

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Health Status, Health Care Access Among Lesbian, Gay, and Bisexual Adults in the US, 2013 to 2018

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Trends in Postmortem Neurodegenerative and Cerebrovascular Neuropathologies Over 25 Years

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Sensitivity and Specificity of the Modified Checklist for Autism in Toddlers

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Aspirin Discontinuation at 24 to 28 Weeks’ Gestation in Pregnancies at High Risk of Preterm Preeclampsia

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Dissemination of the Results of Pediatric Clinical Trials Funded by the National Institutes of Health

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Global Proportion of Disordered Eating in Children and Adolescents

JAMA Pediatrics

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, FEBRUARY 20, 2023

Media advisory: The full study is linked to this news release.

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About The Study: This systematic review and meta-analysis of 32 studies including 63,000 participants from 16 countries found that the overall proportion of children and adolescents with disordered eating was 22%. The proportion was further elevated among girls, as well as with increasing age and body mass index. These high figures are concerning from a public health perspective and highlight the need to implement strategies for preventing eating disorders. 

Authors: Jose Francisco Lopez-Gil, Ph.D., of Universidad de Castilla-La Mancha in Cuenca, Spain, and Hector Gutierrez-Espinoza, Ph.D., of Universidad de las Americas in Quito, Ecuador, are the corresponding authors.

 

(doi:10.1001/jamapediatrics.2022.5848)

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Disparities in Pediatric Medical and Childcare Disruption Due to COVID-19

JAMA Pediatrics

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, FEBRUARY 20, 2023

Media advisory: The full study is linked to this news release.

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About The Study: Researchers found the highest rates of disruptions in childcare arrangements and missed or delayed preventive checkups among low socioeconomic status, Black and multiracial, and urban families during the COVID-19 pandemic. Future research should focus on the association of missing appointments with child health outcomes. 

Authors: Kelsi Batioja, B.S., of Oklahoma State University Center for Health Sciences in Tulsa, is the corresponding author.

 

(doi:10.1001/jamapediatrics.2022.6130)

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Evaluation of Maternal Infection During Pregnancy and Childhood Leukemia Among Offspring

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, FEBRUARY 20, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: The results of this study of 2.2 million Danish children suggest that certain types of maternal infection during pregnancy were associated with an increased risk of childhood leukemia among offspring. If confirmed in future studies, the findings may have implications for understanding the etiology and developing preventive measures for childhood leukemia.           

Authors: Jian-Rong He, D.Phil., of Guangzhou Medical University in Guangzhou, China, and Jiong Li, Ph.D., of Aarhus University in Aarhus, Denmark, are the corresponding authors. 

 

(doi:10.1001/jamanetworkopen.2023.0133)

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History of Low Hourly Wage and All-Cause Mortality Among Middle-Age Workers

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, FEBRUARY 21, 2023

Media advisory: The full study is linked to this news release.

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About The Study: Sustained low-wage earning in midlife may be associated with elevated mortality risk and excess deaths, especially when experienced alongside unstable employment, according to the results of this study including 4,000 workers. If causal, the findings suggest that social and economic policies that improve the financial standing of low-wage workers (e.g., minimum wage laws) could improve mortality outcomes. 

Authors: Katrina L. Kezios, Ph.D., of Columbia University in New York, is the corresponding author.

 

(doi:10.1001/jama.2023.0367)

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Antibiotic Receipt During Outpatient Visits for COVID-19

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About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

Mothers’ Experience With Health Insurance Coverage When Youngest Child Reaches 18 Years of Age

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About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

Association of Hypertensive Disorders of Pregnancy With Future Cardiovascular Disease

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, FEBRUARY 17, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: The findings of this study provide genetic evidence supporting an association between hypertensive disorders of pregnancy and higher risk of coronary artery disease and stroke, which is only partially mediated by cardiometabolic factors. This supports classification of hypertensive disorders of pregnancy as risk factors for cardiovascular disease.           

Authors: Fu Siong Ng, M.B.B.S., Ph.D., of Imperial College London, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.0034)

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Assessment of Social Vulnerability in Pediatric Head and Neck Cancer Care and Prognosis

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, FEBRUARY 17, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: In this study of 37,000 patients with pediatric head and neck cancer, significant decreases in receipt of care and survival time were observed with increasing social determinants of health vulnerability.           

Authors: Jeff C. Rastatter, M.D., M.S., of the Ann & Robert H. Lurie Children’s Hospital of Chicago, and David J. Fei-Zhang, B.A., of the Northwestern University Feinberg School of Medicine in Chicago, are the corresponding authors. 

 

(doi:10.1001/jamanetworkopen.2023.0016)

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Relaunching JAMA Express

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, FEBRUARY 16, 2023

Media advisory: The full editorial is linked to this news release.

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About The Editorial: JAMA is relaunching JAMA Express, a pathway in which manuscripts receive expedited review and processing with the goal of online publication of accepted work within four weeks of submission. 

Authors: Kirsten Bibbins-Domingo, Ph.D., M.D., M.A.S., Editor in Chief, JAMA and the JAMA Network, Chicago, is the corresponding author.

 

(doi:10.1001/jama.2023.2449)

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States’ Methods for Capturing and Reporting Local Responses to Suspected Nonfatal Drug Overdoses

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, FEBRUARY 16, 2023

Media advisory: The full study is linked to this news release.

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About The Study: The findings of this study indicate that not all states comprehensively report nonfatal drug overdoses and current estimates may be undercounted given that not all people who experience an overdose connect with medical services or community programs. 

Authors: Christian Johnson, M.P.H., of the White House Office of National Drug Control Policy in Washington, D.C., is the corresponding author.

 

(doi:10.1001/jama.2023.0169)

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Racial Disparity in Survival From Early-Stage, Hormone-Dependent Breast Cancer

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Diagnostic Accuracy of Amsler Grid Test for Detecting Neovascular Age-Related Macular Degeneration

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Effects of an Immersive Virtual Reality Intervention on Pain, Anxiety Among Pediatric Patients Undergoing a Blood Draw

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, FEBRUARY 16, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: In this randomized clinical trial, integrating procedural information and distraction in an immersive virtual reality (IVR) intervention for pediatric patients undergoing a blood draw significantly improved pain and anxiety in the IVR group compared with the control group. The results shed light on the global trends of research on IVR and its clinical development as an intervention for other painful and stressful medical procedures.           

Authors: Cho Lee Wong, R.N., Ph.D., of the Chinese University of Hong Kong, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.0001)

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Association of Expanded Child Tax Credit Payments With Child Abuse and Neglect Emergency Department Visits

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, FEBRUARY 16, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: This study examined the association of the 2021 expanded child tax credit (CTC) advance payments with child abuse and neglect and found immediate reductions in child abuse and neglect-related emergency department visits in the days following disbursement of the CTC payments. These results are important for discussions of making the temporary expansion of the CTC permanent and are applicable to income support policies more broadly.           

Authors: Lindsey Rose Bullinger, Ph.D., of the Georgia Institute of Technology in Atlanta, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2022.55639)

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Association of Accelerometer-Measured Physical Activity Level With Risks of Hospitalization for Common Health Conditions

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, FEBRUARY 16, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: In this study using accelerometer data from 81,000 UK Biobank participants, those with higher physical activity levels had lower risks of hospitalization across a broad range of health conditions. These findings suggest that aiming to increase moderate to vigorous physical activity by 20 minutes per day may be a useful nonpharmaceutical intervention to reduce health care burdens and improve quality of life.           

Authors: Eleanor L. Watts, D.Phil., of the National Cancer Institute in Rockville, Maryland, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2022.56186)

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Association of Cardiovascular Health With Risk of Clinically Relevant Depressive Symptoms

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Hospitalization Associated With Comorbid Psychiatric, Substance Use Disorders Among Adults With COVID-19

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Performance of a Prediction Model of Suicide Attempts Across Race and Ethnicity

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Trends in Screen Time Use Among Children During Pandemic

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, FEBRUARY 15, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: The findings of this study of 228 children ages 4 to 12 suggest that screen time among children increased during the COVID-19 pandemic and remained elevated even after many public health precautions were lifted. The long-term association of increased screen time during the COVID-19 pandemic with children’s health needs to be determined.            

Authors: Monique M. Hedderson, Ph.D., of the Kaiser Permanente Northern California Division of Research in Oakland, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2022.56157)

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Association of Long COVID Symptoms and Employment Status

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, FEBRUARY 15, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: Among 15,000 individuals with prior COVID-19 infection, those with post–COVID-19 condition (PCC), also known as long COVID, were less likely to be employed full-time and more likely to be unemployed. The presence of cognitive symptoms was associated with diminished likelihood of working full time. These results underscore the importance of developing strategies to treat and manage PCC symptoms.           

Authors: Roy H. Perlis, M.D., M.Sc., of Massachusetts General Hospital in Boston, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2022.56152)

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Assessment of Symptom, Disability, Financial Trajectories in Patients Hospitalized for COVID-19 at 6 Months

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, FEBRUARY 14, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: The findings of this study of adults discharged after COVID-19 hospitalization suggest that symptoms, disabilities, and financial problems remained highly prevalent at six months. Some participants reported new problems six months after hospital discharge.

Authors: Andrew J. Admon, M.D., M.P.H., M.S., of the University of Michigan Medical School in Ann Arbor, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2022.55795)

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Association of COVID-19 Vaccination With Risk for New-Onset Diabetes After COVID-19 Infection

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, FEBRUARY 14, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: COVID-19 infection was associated with an increased risk of diabetes, with the results of this study suggesting that this risk persisted as the Omicron variant became predominant. Diabetes risk after COVID-19 infection was higher in unvaccinated than vaccinated patients, suggesting a benefit of vaccination.           

Authors: Alan C. Kwan, M.D., M.Sc., of Cedars Sinai Medical Center Los Angeles, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2022.55965)

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Assessment of FDA-Approved Drugs Not Recommended for Use or Reimbursement in Other Countries

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FDA Approval of Drugs Not Meeting Pivotal Trial Primary End Points

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Effect of Low-Concentration Atropine Eyedrops vs Placebo on Incidence of Nearsightedness in Children

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Childhood Educational Quality and Incident Dementia in Black and White Adults

JAMA Neurology

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, FEBRUARY 13, 2023

Media advisory: The full study is linked to this news release.

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About The Study: In this study, lower state-average educational quality was more common among Black individuals and associated with higher dementia risk. Differential investment in high-quality education due to structural racism may contribute to dementia disparities.

Authors: Yenee Soh, Sc.D., of Kaiser Permanente Northern California in Oakland, is the corresponding authors.

 

(doi:10.1001/jamaneurol.2022.5337)

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Changes in BMI in School-Aged Youths After Implementation of Healthy, Hunger-Free Kids Act of 2010

JAMA Pediatrics

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, FEBRUARY 13, 2023

Media advisory: The full study and editorial are linked to this news release.

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About The Study: The results of this study of 14,000 youths ages 5 to 18 suggest that implementation of the Healthy, Hunger-Free Kids Act of 2010 was associated with reduced body mass index (BMI) among youths. The findings suggest that school meal programs represent a key opportunity for interventions to combat the childhood obesity epidemic given the high rates of program participation and the proportion of total calories consumed through school-based meals. 

Authors: Aruna Chandran, M.D., M.P.H., of the Johns Hopkins Bloomberg School of Public Health in Baltimore, is the corresponding author.

 

(doi:10.1001/jamapediatrics.2022.5828)

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USPSTF Recommendation Statement on Serologic Screening for Genital Herpes Infection

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, FEBRUARY 14, 2023

Media advisory: To contact the U.S. Preventive Services Task Force, email the Media Coordinator at Newsroom@USPSTF.net or call 301-951-9203. The full report and related articles are linked to this news release.

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Bottom Line: The U.S. Preventive Services Task Force (USPSTF) recommends against routine serologic screening for genital herpes simplex virus infection in asymptomatic adolescents and adults, including pregnant persons. Genital herpes is a common sexually transmitted infection caused by two related viruses, herpes simplex type 1 (HSV-1) and herpes simplex type 2 (HSV-2). Infection is lifelong; currently, there is no cure for HSV infection. Antiviral medications may provide clinical benefits to symptomatic persons. The USPSTF routinely makes recommendations about the effectiveness of preventive care services and this statement is consistent with its 2016 recommendation.

 

(doi:10.1001/jama.2023.0057)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.

Note: More information about the U.S. Preventive Services Task Force, its process, and its recommendations can be found on the newsroom page of its website.

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Effect of Vaginal CO2 vs Sham Laser on Sexual Function in Breast Cancer Survivors Receiving Aromatase Inhibitors for Genitourinary Syndrome

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Implementation of a Multimodal Knowledge-Exchange Platform to Provide Trauma Critical Care Education in Ukraine

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, FEBRUARY 10, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: The findings of this study suggest that simple tele-education interventions can rapidly and efficiently share best practices in the care of critically ill wartime casualties to a large community of clinicians practicing in an area of active conflict.           

Authors: Alexander S. Niven, M.D., of the Mayo Clinic in Rochester, Minnesota, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.0050)

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Comparison of Prices for Commonly Administered Drugs in Employer-Sponsored Insurance Relative to Medicare

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About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

Association of Long-term Exposure to Air Pollution With Late-Life Depression in Older Adults

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, FEBRUARY 10, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: Harmful associations were observed between long-term exposure to air pollution and increased risk of a late-life depression diagnosis in this study including 8.9 million Medicare enrollees. 

Authors: Xinye Qiu, Ph.D., of the Harvard T.H. Chan School of Public Health in Boston, and Liuhua Shi, Sc.D., of Emory University in Atlanta, are the corresponding authors. 

 

(doi:10.1001/jamanetworkopen.2022.53668)

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Association of Past and Future Paid Medical Malpractice Claims

JAMA Health Forum

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, FEBRUARY 10, 2023

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama-health-forum/fullarticle/10.1001/jamahealthforum.2022.5436?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=021023

About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

 

About The Study: In this study of paid medical malpractice claims for all U.S. physicians at the time of the study, a single prior paid claim was associated with substantial, long-lived higher future claim risk, independent of whether a physician was practicing in a high- or low-risk specialty, or whether a state publicly disclosed paid claims. Timely, noncoercive intervention, including education, has the potential to reduce future claims. 

Authors: David A. Hyman, J.D., M.D., of the Georgetown University Law Center in Washington, D.C., is the corresponding author.

 

(doi:10.1001/jamahealthforum.2022.5436)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Association Between Antimicrobial Stewardship Programs and Antibiotic Use Globally

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, FEBRUARY 9, 2023

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2022.53806?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=020923

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: In this systematic review and meta-analysis of 52 studies with more than 1.7 million patients conducted in different health care and income settings, antimicrobial stewardship programs appeared to be effective in reducing antibiotic consumption in both hospital and nonhospital settings. Impact assessment of antimicrobial stewardship programs in resource-limited settings remains scarce; further research is needed on how to best achieve reductions in antibiotic use in low- and middle-income countries. 

Authors: Kyaw Zay Ya, M.B., B.S., M.P.H., of the Swiss Tropical and Public Health Institute in Allschwil, Switzerland, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2022.53806)

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Association of Recent SARS-CoV-2 Infection With New-Onset Alcohol Use Disorder

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, FEBRUARY 9, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: The results of this study using electronic health records of 2.8 million patients suggest that the risk of a new diagnosis of alcohol use disorder after a COVID-19 diagnosis may not be a consequence of the infection itself but rather associated with the context of the diagnosis and the pandemic. 

Authors: Pamela B. Davis, M.D., Ph.D., of Case Western Reserve University in Cleveland, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2022.55496)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Racial and Sex Disparities in Resident Attrition Among Surgical Subspecialties

JAMA Surgery

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, FEBRUARY 8, 2023

Media advisory: The full study and commentary are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamasurgery/fullarticle/10.1001/jamasurg.2022.7640?guestAccessKey=0da90f2b-b925-4bd9-bbec-1f4b6e4bac08&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=020823

 

About The Study: Results of this study suggest that the percentage of female residents in surgical specialties has improved over the last 18 years, and the percentage of underrepresented in medicine residents has remained relatively unchanged. Risk for attrition and unintended attrition was significantly elevated for female and underrepresented in medicine residents, specifically Black/African Americans. These results highlight current racial and sex disparities in resident attrition and demonstrate the importance of developing strategies to recruit, retain, and support residents.

Authors: Lee S. Haruno, M.D., of Cedars Sinai Medical Center in Los Angeles, is the corresponding author.

 

(doi:10.1001/jamasurg.2022.7640)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Association of Familial Aggregation of Major Depression With Risk of Major Depression

JAMA Psychiatry

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, FEBRUARY 8, 2023

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapsychiatry/fullarticle/10.1001/jamapsychiatry.2022.4965?guestAccessKey=627b9891-1819-41c1-b237-7bef6dce6a0a&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=020823

 

About The Study: In this study of 2.9 million individuals, risk of major depression was associated with increased numbers of affected family members but did not vary by gender or type of kinship. Exposure to family major depression during childhood and adolescence was associated with increased risk.

Authors: Frederikke Hørdam Gronemann, Ph.D., Msc., of Copenhagen University Hospital–Bispebjerg and Frederiksberg in Frederiksberg, Denmark, is the corresponding author.

 

(10.1001/jamapsychiatry.2022.4965)

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Association Between Opioid Tapering and Subsequent Health Care Use, Medication Adherence, Chronic Condition Control

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, FEBRUARY 7, 2023

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2022.55101?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=020723

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: In this study of patients prescribed long-term opioid therapy, opioid tapering was associated with more emergency department visits and hospitalizations, fewer primary care visits, and reduced antihypertensive and antidiabetic medication adherence. These outcomes may represent unintended negative consequences of opioid tapering for policy makers and clinicians to consider. 

Authors: Elizabeth M. Magnan, M.D., Ph.D., of the University of California, Davis, in Sacramento, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2022.55101)

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Prediction of Longitudinal Cognitive Decline in Preclinical Alzheimer Disease Using Plasma Biomarkers

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaneurology/fullarticle/10.1001/jamaneurol.2022.5272?guestAccessKey=9c585b26-8f7a-4f15-b722-e672ab9fbe34&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=020623

Accuracy of EHR Food Insecurity, Housing Instability, Financial Strain Screening in Primary Care

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Adherence to Healthy Lifestyle Prior to Infection and Risk of Long COVID

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, FEBRUARY 6, 2023

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/10.1001/jamainternmed.2022.6555?guestAccessKey=a9998ba9-a64c-4674-a761-dfb50e5c1c43&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=020623

 

About The Study: In this study of 1,981 women who reported a positive SARS-CoV-2 test, pre-infection healthy lifestyle was associated with a substantially lower risk of post–COVID-19 condition (PCC), informally known as long COVID. Future research should investigate whether lifestyle interventions may reduce risk of developing PCC or mitigate symptoms among individuals with PCC or possibly other post-infection syndromes. 

Authors: Siwen Wang, M.D., of the Harvard T.H. Chan School of Public Health in Boston, is the corresponding author.

 

(doi:10.1001/jamainternmed.2022.6555)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Infant Pertussis Incidence Trends Before, After Implementation of Maternal Tdap Vaccine

JAMA Pediatrics

EMBARGOED FOR RELEASE: 11:10 A.M. (ET), MONDAY, FEBRUARY 6, 2023

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapediatrics/fullarticle/10.1001/jamapediatrics.2022.5689?guestAccessKey=5fb10558-339c-4669-b6ba-95a06f409714&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=020623

 

About The Study: In this study of 57,460 pertussis (also known as whooping cough) cases in the United States, following maternal tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine introduction, a sustained decrease in pertussis incidence was observed among infants younger than 2 months, narrowing the incidence gap with infants ages 6 months to less than 12 months. These findings suggest that maternal Tdap vaccination is associated with a reduction in pertussis burden in the target age group (younger than 2 months) and that further increases in coverage may be associated with additional reductions in infant disease. 

Authors: Tami H. Skoff, M.S., of the Centers for Disease Control and Prevention in Atlanta, is the corresponding author.

 

(doi:10.1001/jamapediatrics.2022.5689)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Association Between Drug Characteristics and Manufacturer Spending on Direct-to-Consumer Advertising

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, FEBRUARY 7, 2023

Media advisory: The full study and editorial are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2022.23968?guestAccessKey=8bf5d2a0-046b-47f5-b948-86efed6dddad&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=020723

 

About The Study: Among top-selling U.S. prescription drugs in 2020, a rating of lower added benefit and higher total drug sales were associated with a higher proportion of manufacturer total promotional spending allocated to direct-to-consumer advertising. Further research is needed to understand the implications of these findings. 

Authors: Michael J. DiStefano, Ph.D., of the Bloomberg School of Public Health in Baltimore, is the corresponding author.

 

(doi:10.1001/jama.2022.23968)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Breast, Lung Cancer Screening Among Medicare Enrollees During Pandemic

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, FEBRUARY 3, 2023

Media advisory: The full study and commentary are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2022.55589?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=020323

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: The decreases in cancer screening during the early phases of the COVID-19 pandemic did not resolve after the initial pandemic surges in this study of Medicare enrollees from March 2020 through July 2022. Successful interventions to improve screening rates should address pandemic-specific reasons for low screening participation. 

Authors: James S. Goodwin, M.D., of the University of Texas Medical Branch in Galveston, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2022.55589)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Estimated Effectiveness of CoronaVac, Pfizer-BioNTech Vaccines Over Time Among Patients With SARS-CoV-2 Omicron

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, FEBRUARY 3, 2023

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2022.54777?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=020323

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: In this case-control study with 164,000 participants, the CoronaVac and Pfizer-BioNTech vaccines were generally estimated to be effective against severe outcomes due to SARS-CoV-2 Omicron infection, but protection among older individuals was more likely to wane six months after the second dose. Hence, a booster dose is recommended for older patients to restore immunity. 

Authors: Ka Chun Chong, Ph.D., and Eng Kiong Yeoh, M.B.B.S., of the Chinese University of Hong Kong, are the corresponding authors. 

 

(doi:10.1001/jamanetworkopen.2022.54777)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Breast Cancer Diagnosis, Treatment, and Outcomes of Patients From Sex and Gender Minority Groups

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaoncology/fullarticle/10.1001/jamaoncol.2022.7146?guestAccessKey=5044452f-d914-4408-a491-41b304732f6a&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=020223