Pet Ownership, Living Alone, and Cognitive Decline Among Adults Age 50 and Older

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, DECEMBER 26, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: Pet ownership was associated with slower rates of decline in verbal memory and verbal fluency among older adults living alone, but not among those living with others in this study of 7,900 participants age 50 and older. Pet ownership offset the associations between living alone and declining rates in verbal memory and verbal fluency. Further studies are needed to assess whether pet ownership slows the rate of cognitive decline in older adults living alone. 

Authors: Ciyong Lu, Ph.D., of Sun Yat-sen University in Guangzhou, China, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.49241)

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Negative Wealth Shock and Cognitive Decline and Dementia in Middle-Aged and Older Adults

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, DECEMBER 26, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this study of 8,000 participants, negative wealth shock (a loss of 75% or more in total wealth over a 2-year period) was associated with accelerated cognitive decline and elevated risks of dementia among middle-aged and older U.S. adults, with modifications by age and ethnicity. These findings should be confirmed by further prospective and interventional studies. 

Authors: Jing Guo, Ph.D., of the Zhejiang University School of Medicine in Hangzhou, China, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.49258)

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Variation by Institution in Sexual Harassment Experiences Among Medical Interns

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, DECEMBER 26, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: Among a national cohort of medical interns, over half experienced sexual harassment. Although harassment was prevalent across programs, institutional and specialty training variations in interns’ sexual harassment experiences exist, thereby providing additional evidence that residency programs and institutions play an important role in combating this widespread problem. 

Authors: Elizabeth M. Viglianti, M.D., M.P.H., M.Sc., of the University of Michigan in Ann Arbor, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.49129)

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Changes in Hospital Adverse Events and Patient Outcomes Associated With Private Equity Acquisition

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, DECEMBER 26, 2023

Media advisory: The full study is linked to this news release.

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About The Study: Private equity acquisition of hospitals, on average, was associated with increased hospital-acquired adverse events despite a likely lower-risk pool of admitted Medicare beneficiaries, suggesting poorer quality of inpatient care. These findings heighten concerns about the implications of private equity on health care delivery. 

Authors: Zirui Song, M.D., Ph.D., of Harvard Medical School in Boston, is the corresponding author.

 

(doi:10.1001/jama.2023.23147)

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Wearable Biosensing to Predict Imminent Aggressive Behavior in Psychiatric Inpatient Youths With Autism

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, DECEMBER 21, 2023

Media advisory: The full study and commentary are linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: The results of this study involving 70 youths with autism across four psychiatric inpatient hospitals suggest that wearable biosensing and machine learning may hold promise for identifying objective indicators of impending aggressive behaviors in youths with autism who are psychiatric inpatients. The findings may lay the groundwork for developing just-in-time adaptive intervention mobile health systems that may enable new opportunities for preemptive intervention. 

Authors: Matthew S. Goodwin, Ph.D., of Northeastern University in Boston, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.48898)

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Race and Ethnicity of Infants Enrolled in Neonatal Clinical Trials

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, DECEMBER 21, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: This systematic review of 120 studies with 14,000 participants found that Asian, Black, Hispanic, and Indigenous (e.g., Alaska Native, American Indian, and Native Hawaiian) participants were underrepresented in neonatal clinical trials, while white participants were overrepresented. There was wide variation in the terms used to report race and ethnicity data, and geographic representation was unevenly distributed, with some central and western U.S. regions underrepresented. 

Authors: Elliott M. Weiss, M.D., M.S.M.E., of the University of Washington School of Medicine in Seattle, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.48882)

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Newborn Brain Function and Early Emerging Callous-Unemotional Traits

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Withdrawal of Life-Sustaining Treatment for Pediatric Patients With Severe Traumatic Brain Injury

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Innovation in Development of Dermatologic Drugs Approved by the FDA

JAMA Dermatology

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, DECEMBER 20, 2023

Media advisory: The full study is linked to this news release.

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About The Study: Compared with prior decades, the number of new dermatologic drug approvals by the Food and Drug Administration (FDA) increased between 2012 and 2022. Nearly half of these drugs were considered first in class or first in indication, and several were deemed clinically useful or to have high added therapeutic benefit by health technology assessment organizations in Germany, Canada, or France.

Authors: Ravi Gupta, M.D., M.S.H.P., of the Johns Hopkins University School of Medicine in Baltimore, is the corresponding author.

 

(doi:10.1001/jamadermatol.2023.5036)

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Home-Delivered Meals and Nursing Home Placement Among People With Self-Reported Dementia

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, DECEMBER 20, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: This pilot pragmatic clinical trial included 243 homebound older adults with self- or proxy-reported dementia found a lower although nonsignificant likelihood of nursing home placement among those receiving daily-delivered meals compared with those receiving drop-shipped frozen meals. While this study was not powered to detect meaningful, statistically significant differences in nursing home placement, its feasibility and initial results warrant exploration in an adequately powered trial. 

Authors: Kali S. Thomas, Ph.D., of the Brown University School of Public Health in Providence, Rhode Island, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.47195)

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Trainee-Led Intervention to Motivate Resident Physician Voter Registration

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Hypothermia vs Normothermia in Patients With Cardiac Arrest and Nonshockable Rhythm

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Trends in HPV Vaccination Before Age 13 Years in the US National Immunization Survey–Teen

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Association Between Daily Toothbrushing and Hospital-Acquired Pneumonia

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, DECEMBER 18, 2023

Media advisory: The full study and commentary are linked to this news release.

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About The Study: The findings of this systematic review and meta-analysis of 15 randomized clinical trials with an effective population size of 2,786 patients suggest that daily tooth brushing may be associated with significantly lower rates of hospital-acquired pneumonia, particularly in patients receiving mechanical ventilation, lower rates of intensive care unit (ICU) mortality, shorter duration of mechanical ventilation, and shorter ICU length of stay. Policies and programs encouraging more widespread and consistent toothbrushing are warranted. 

Authors: Michael Klompas, M.D., M.P.H., of Harvard Medical School and Harvard Pilgrim Health Care Institute in Boston, is the corresponding author.

 

(doi:10.1001/jamainternmed.2023.6638)

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Public Benefit Programs and Differential Associations With Child Maltreatment by Race and Ethnicity

JAMA Pediatrics

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, DECEMBER 18, 2023

Media advisory: The full study is linked to this news release.

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About The Study: The results of this study raise concerns that benefit programs may add relative advantages for white children compared with Black and Hispanic children and contribute to racial and ethnic disparities in child protective services investigations. States’ eligibility criteria and distribution practices should be examined to promote equitable effects on adverse child outcomes. 

Authors: Henry T. Puls, M.D., of Children’s Mercy Kansas City, is the corresponding author.

 

(doi:10.1001/jamapediatrics.2023.5521)

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Measuring the Impact of AI in the Diagnosis of Hospitalized Patients

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, DECEMBER 19, 2023

Media advisory: The full study and editorial are linked to this news release.

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About The Study: Although standard artificial intelligence (AI) models improve diagnostic accuracy, systematically biased AI models reduced diagnostic accuracy, and commonly used image-based AI model explanations did not mitigate this harmful effect in this multicenter randomized clinical vignette survey study involving hospitalist physicians, nurse practitioners, and physician assistants from 13 states. 

Authors: Michael W. Sjoding, M.D., of the University of Michigan Medical School, and Jenna Wiens, Ph.D., of the University of Michigan, Ann Arbor, are the corresponding authors.

 

(doi:10.1001/jama.2023.22295)

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The Comprehensive Primary Care Plus Model and Health Care Spending, Service Use, and Quality

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Estimated Savings From the Medicare Shared Savings Program

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About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

Racial Equity in Living Donor Kidney Transplant Centers

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, DECEMBER 15, 2023

Media advisory: The full study and commentary are linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: The results of this study of data on 57,000 adults who received living donor kidney transplants indicate that additional work is necessary to identify transplant program and center-level strategies to improve racial equity in access to living donor kidney transplant. 

Authors: Lisa M. McElroy, M.D., M.S., of the Duke University School of Medicine in Durham, North Carolina, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.47826)

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Screening for Social Determinants of Health During Primary Care and Emergency Department Encounters

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, DECEMBER 19, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: This study found that patients screened in the emergency department (ED) were more likely to screen positive for Social Determinants of Health (SDOH) needs, which is not surprising given utilization patterns. Patients with SDOH needs have limited health care access and are more likely to use the ED than primary care. Although primary care–based screening found lower SDOH needs relative to the ED, primary care may be better optimized to follow and ultimately address SDOH needs.

Authors: Stacie Vilendrer, M.D., M.B.A., M.S.H.P., of the Stanford University School of Medicine, in Palo Alto, California is the corresponding author.

 

(doi: 10.1001/jamanetworkopen.2023.48646)

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Disparities in Preoperative Goals of Care Documentation in Veterans

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, DECEMBER 19, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: In this study of 13,000 patients, few patients undergoing surgical procedures completed preoperative life-sustaining treatment documentation, with disparities in documentation rates based on race, ethnicity, rurality of patient residence, history of mental health disability, and access to high-volume facilities within a Veterans Affairs cohort.

Authors: Adela Wu, M.D., of the U.S. Department of Veterans Affairs, in Palo Alto, California is the corresponding author.

 

(doi: 10.1001/jamanetworkopen.2023.48235)

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Menu Labeling and Calories Purchased in Restaurants in a National Fast Food Chain

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, DECEMBER 15, 2023

Media advisory: The full study and commentary are linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: Fewer calories were purchased in restaurants with calorie labels compared with those with no labels, suggesting that consumers are sensitive to calorie information on menu boards, according to the results of this study of 2,329 Mexican-inspired fast food restaurants in six U.S. locations. Associations differed by location. 

Authors: Brian Elbel, Ph.D., M.P.H., of the New York University School of Medicine in New York, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.46851)

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Development of Deep Ensembles to Screen for Autism and Symptom Severity Using Retinal Photographs

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, DECEMBER 15, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: The findings of this diagnostic study of 1,890 eyes of 958 participants support the potential of artificial intelligence as an objective tool in screening for autism spectrum disorder (ASD) and possibly for symptom severity using retinal photographs. Retinal photograph use may speed the ASD screening process, which may help improve accessibility to specialized child psychiatry assessments currently strained by limited resources. 

Authors: Yu Rang Park, Ph.D., and Keun-Ah Cheon, M.D., Ph.D., of the Yonsei University College of Medicine in Seoul, Republic of Korea, are the corresponding authors. 

 

(doi:10.1001/jamanetworkopen.2023.47692)

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Well-Being Parameters and Intention to Leave Current Institution Among Academic Physicians

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, DECEMBER 15, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this study of 18,000 academic physicians, approximately one-third reported moderate or greater intention to leave within two years. Burnout, lack of professional fulfillment, and other well-being factors were associated with intention to leave, suggesting the need for a comprehensive approach to reduce physician turnover. 

Authors: Mickey T. Trockel, M.D., Ph.D., of the Stanford University School of Medicine in Stanford, California, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.47894)

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Clinical Characteristics of Primary Snoring vs Mild Obstructive Sleep Apnea in Children

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Neighborhood-Level Socioeconomic Status and Prescription Fill Patterns Among Patients With Heart Failure

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, DECEMBER 14, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this study of 6,247 patients with heart failure with reduced ejection fraction, patients living in neighborhoods with lower neighborhood-level socioeconomic status had significantly higher odds of nonadherence to guideline-directed medical therapy. These findings highlight the importance of considering neighborhood-level disparities when developing approaches to improve medication adherence. 

Authors: Amrita Mukhopadhyay, M.D., of the NYU Grossman School of Medicine in New York, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.47519)

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Sleep Disturbances and Emotional and Behavioral Difficulties Among Preschool-Aged Children

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, DECEMBER 14, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: The natural history of sleep disturbances was associated with both resolved and incident emotional and behavioral difficulties in this study of 17,000 preschool-aged children. Routine screening and precise intervention for sleep disturbances may benefit the psychosocial well-being of this population. 

Authors: Fan Jiang, M.D., Ph.D., and Guanghai Wang, Ph.D., of Shanghai Jiao Tong University in Shanghai, are the corresponding authors. 

 

(doi:10.1001/jamanetworkopen.2023.47623)

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Medical Students’ Perspectives on Family Planning and Impact on Specialty Choice

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Benign Breast Disease and Breast Cancer Risk in the Percutaneous Biopsy Era

JAMA Surgery

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, DECEMBER 13, 2023

Media advisory: The full study and commentary are linked to this news release.

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About The Study: In this study including 4,819 women with benign breast disease (BBD) in the percutaneous biopsy era, overall risk of breast cancer was increased versus the general population (ductal carcinoma in situ and invasive cancer combined), similar to that in historical BBD cohorts. Development and validation of pathologic classifications including both BBD severity and multiplicity may enable improved breast cancer risk stratification.

Authors: Amy C. Degnim, M.D., of the Mayo Clinic in Rochester, Minnesota, is the corresponding author.

 

(doi:10.1001/jamasurg.2023.6382)

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Use of E-Cigarettes and Cigarettes During Late Pregnancy Among Adolescents

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, DECEMBER 13, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: The findings from this study using 2016-2021 data on 10,000 adolescents in the U.S. suggest that pregnant adolescents increasingly used e-cigarettes, with the highest use among white adolescents. Results from this analysis found that, unlike cigarette use, e-cigarette use during late pregnancy was not statistically significantly associated with an increased risk of small-for-gestational-age birth among adolescents. Due to the uncertainty of this nonsignificant association, future research could benefit from a larger sample size. 

Authors: Xiaozhong Wen, M.D., Ph.D., of the State University of New York at Buffalo, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.47407)

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Safety of GLP-1 Receptor Agonists and Other Second-Line Antidiabetics in Early Pregnancy

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Trends in Age and Disease Severity in Children Hospitalized With RSV Infection Before and During the Pandemic

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Continued Treatment With Tirzepatide for Maintenance of Weight Reduction in Adults With Obesity

JAMA

EMBARGOED FOR RELEASE: 10 A.M. (ET), MONDAY, DECEMBER 11, 2023

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https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2023.24945?guestAccessKey=753fc442-37ad-47c9-9aac-307204ec3055&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=121123 

 

About The Study: In participants with obesity or overweight, withdrawing tirzepatide led to substantial regain of lost weight, whereas continued treatment maintained and augmented initial weight reduction in this randomized clinical trial that included 670 adults.  

Authors: Louis J. Aronne, M.D., of Weill Cornell Medicine in New York, is the corresponding author.

 

(doi:10.1001/jama.2023.24945)

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Adolescent Body Mass Index and Early Chronic Kidney Disease in Young Adulthood

JAMA Pediatrics

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, DECEMBER 11, 2023

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About The Study: High body mass index (BMI) in late adolescence was associated with early chronic kidney disease in young adulthood in this study that included 593,000 adolescents. The risk was also present in seemingly healthy individuals with high-normal BMI and before 30 years of age, and a greater risk was seen among those with severe obesity. These findings underscore the importance of mitigating adolescent obesity rates and managing risk factors for kidney disease in adolescents with high BMI. 

Authors: Gilad Twig, M.D., Ph.D., of the Israel Defense Forces, Medical Corps, Tel Hashomer, Ramat Gan, Israel, is the corresponding author.

 

(doi:10.1001/jamapediatrics.2023.5420)

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Metformin Plus Insulin for Preexisting Diabetes or Gestational Diabetes in Early Pregnancy

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, DECEMBER 12, 2023

Media advisory: The full study and editorial are linked to this news release.

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About The Study: Using metformin plus insulin to treat preexisting type 2 or gestational diabetes diagnosed early in pregnancy did not reduce a composite neonatal adverse outcome in a randomized clinical trial of 794 pregnant adults. The effect of reduction in odds of a large-for-gestational-age infant observed after adding metformin to insulin warrants further investigation. 

Authors: Kim A. Boggess, M.D., of the University of North Carolina at Chapel Hill, is the corresponding author.

 

(doi:10.1001/jama.2023.22949)

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Cannabis Exposure and Adverse Pregnancy Outcomes Related to Placental Function

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, DECEMBER 12, 2023

Media advisory: The full study is linked to this news release.

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About The Study: In a multicenter observational cohort, a composite adverse pregnancy outcome (small-for-gestational-age birth, medically indicated preterm birth, stillbirth, or hypertensive disorders of pregnancy) was more frequent in pregnant individuals with cannabis exposure ascertained by a urine drug assay compared with unexposed individuals. The risk for an adverse outcome was higher among those who continued to use cannabis beyond the first trimester. 

Authors: Torri Metz, M.D., M.S., of University of Utah Health in Salt Lake City, is the corresponding author.

 

(doi:10.1001/jama.2023.21146)

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County–Level Variation in Preterm Birth Rates

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, DECEMBER 8, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this analysis of U.S. county-level preterm and early preterm birth rates, substantial geographic disparities were observed, which were associated with place-based social disadvantage. Stability in aggregated rates of preterm birth at the national level masked increases in nearly 1 in 6 counties between 2007 and 2019. 

Authors: Sadiya S. Khan, M.D.,M.S., of the Northwestern University Feinberg School of Medicine in Chicago, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.46864)

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Racial and Ethnic Differences in Hospice Use Among Medicaid-Only and Dual-Eligible Decedents

JAMA Health Forum

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, DECEMBER 8, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

 

About The Study: In this study, in both Medicaid only and dual-eligible populations, Hispanic and non-Hispanic Black individuals had the lowest odds of receiving hospice, and Hispanic individuals had the highest odds of a short hospice stay. Knowledge about, access to, and acceptance of hospice may be lacking for these low-income individuals. Further research is needed to understand barriers to and facilitators of hospice use for people with nursing facility stays. 

Authors: Julie Robison, Ph.D., of UConn Health, Center on Aging in Farmington, Connecticut, is the corresponding author.

 

(doi:10.1001/jamahealthforum.2023.4240)

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Telehealth Mindfulness-Oriented Recovery Enhancement vs Usual Care in Individuals With Opioid Use Disorder and Pain

JAMA Psychiatry

EMBARGOED FOR RELEASE: 7:45 P.M. (ET), THURSDAY, DECEMBER 7, 2023

Media advisory: The full study is linked to this news release. This study is being released to coincide with presentation at the American Academy of Addiction Psychiatry 34th Annual Meeting and Scientific Symposium.

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About The Study: In this randomized clinical trial of 154 individuals with chronic pain in methadone treatment for an opioid use disorder, relative to usual care, Mindfulness-Oriented Recovery Enhancement (MORE) plus usual care demonstrated efficacy for decreasing drug use, pain, and depression and increasing methadone treatment retention and adherence. Participants receiving MORE attended eight weekly, 2-hour telehealth groups that provided training in mindfulness, reappraisal, and savoring in addition to usual care.

Authors: Nina Cooperman, Psy.D., of Rutgers Robert Wood Johnson Medical School in Piscataway, New Jersey, is the corresponding author.

 

(10.1001/jamapsychiatry.2023.5138)

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Pregnancy After Breast Cancer in Young BRCA Carriers

JAMA

EMBARGOED FOR RELEASE: 9:15 A.M. (ET), THURSDAY, DECEMBER 7, 2023

Media advisory: The full study is linked to this news release. This study is being released to coincide with presentation at the San Antonio Breast Cancer Symposium 2023.

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About The Study: This international, hospital-based, retrospective cohort study including 4,732 BRCA carriers showed that 1 in 5 patients conceived within 10 years after breast cancer diagnosis. Pregnancy following breast cancer in BRCA carriers was not associated with decreased disease-free survival.

Authors: Matteo Lambertini, M.D., of the University of Genova in Genova, Italy, is the corresponding author.

 

(doi:10.1001/jama.2023.25463)

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Percutaneous Coronary Intervention–Capable Facility Openings and Heart Attack Outcomes by Patient Race and Community Segregation

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, DECEMBER 12, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: This study found differential benefits associated with a percutaneous coronary intervention–capable facility (PCI-CF) opening based on patient race and community segregation. Black patients in integrated communities demonstrated the greatest benefits across all outcomes, including a five times greater likelihood of receiving same-day PCI after a PCI-CF opening compared with white patients in segregated communities.

Authors: Renee Y. Hsia, M.D., M.Sc., of the University of California, San Francisco, is the corresponding author.

 

(doi: 10.1001/jamanetworkopen.2023.47311)

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COVID-19 Symptoms and Economic Hardship Among US Families

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, DECEMBER 12, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: The findings of this study suggest that persistent COVID-19 symptoms and, to a lesser extent, previous severe COVID-19 were associated with increased odds of pandemic-related economic hardship in a cohort of U.S. families. The economic consequences of COVID-19 varied according to socioeconomic status; families with lower income before the pandemic were more vulnerable to employment disruptions and earnings losses associated with an adult family member’s COVID-19 illness.

Authors: Nicole L. Hair, Ph.D., of the University of South Carolina Arnold School of Public Health in Columbia, is the corresponding author.

 

(doi: 10.1001/jamanetworkopen.2023.47318)

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Population Attributable Risk of Advanced-Stage Breast Cancer by Race and Ethnicity

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Effectiveness of Aerobic Exercise and Tai Chi Interventions on Sleep Quality in Patients With Advanced Lung Cancer

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Global, Regional, and National Epidemiology of Visual Impairment In Working-Age Individuals

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Racial and Ethnic Disparities in Clinical Trial Enrollment Among Women With Gynecologic Cancer

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, DECEMBER 7, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: Clinical trial enrollment was lower among certain minoritized racial and ethnic groups in this study of 562,000 women with endometrial, ovarian, or cervical cancer. Continued efforts are needed to address disparate clinical trial enrollment among underrepresented groups. 

Authors: Ashley S. Felix, Ph.D., of Ohio State University in Columbus, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.46494)

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Opioid Prescribing by Surgeons

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, DECEMBER 7, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: This study found that during 2016 to 2022, the rate and size of opioid prescriptions from U.S. surgeons declined, but these declines were slower after mid-2020 compared with before 2020. During the initial months of the COVID-19 pandemic, the opioid dispensing rate declined, potentially owing to decreased surgical volume, while opioid prescription size increased, potentially because surgeons wrote larger discharge prescriptions owing to barriers to obtaining refills. However, these changes were transient. 

Authors: Kao-Ping Chua, M.D., Ph.D., of the University of Michigan Medical School in Ann Arbor, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.46426)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Risk Prediction for Atherosclerotic Cardiovascular Disease With and Without Race Stratification

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Clinical Outcomes of Magnetic Seizure Therapy vs Electroconvulsive Therapy for Major Depressive Episode

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Single-Dose Synthetic Psilocybin With Psychotherapy for Treatment-Resistant Bipolar Type II Major Depressive Episodes

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Analyzing Surgical Technique in Diverse Open Surgical Videos With Multitask Machine Learning

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Treatment of Severe Palmoplantar Pustular Psoriasis With Bimekizumab

JAMA Dermatology

EMBARGOED FOR RELEASE: 8:15 A.M. (ET), WEDNESDAY, DECEMBER 6, 2023

Media advisory: The full study is linked to this news release. This study is being released to coincide with presentation at Journées Dermatologiques de Paris 2023.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamadermatology/fullarticle/10.1001/jamadermatol.2023.5051?guestAccessKey=3599d068-5c7a-4564-91b3-968f559d7d21&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=120623

 

About The Study: The findings of this case series of 21 patients suggest that bimekizumab could be an appealing approach for treating palmoplantar pustulosis, palmoplantar plaque psoriasis with pustules, and SAPHO (synovitis, acne, pustulosis, hyperostosis, osteitis) syndrome. Bimekizumab is an anti–IL-17A and anti–IL-17F antibody therapy that has been useful for treating psoriasis and psoriatic arthritis. Prospective randomized placebo-controlled clinical trials are needed to confirm these encouraging initial results.

Authors: Thierry Passeron, M.D., Ph.D., of the Université Côte d’Azur in Nice, France, is the corresponding author.

 

(doi:10.1001/jamadermatol.2023.5051)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Economic Burden of Health Conditions Associated With Adverse Childhood Experiences Among US Adults

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, DECEMBER 6, 2023

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2023.46323?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=120623

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this cross-sectional analysis of the U.S. adult population, 63% of adults had adverse childhood experiences (ACEs). The economic burden of ACE-related health conditions was substantial. The findings suggest that measuring the economic burden of ACEs can support decision-making about investing in strategies to improve population health. 

Authors: Cora Peterson, Ph.D., of the Centers for Disease Control and Prevention in Atlanta, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.46323)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Evaluation of Stigma Toward Individuals With Acne

JAMA Dermatology

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, DECEMBER 6, 2023

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamadermatology/fullarticle/10.1001/jamadermatol.2023.4487?guestAccessKey=39c38e87-cb87-4f98-a6af-ea7cacac8823&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=120623

 

About The Study: This survey study with 1,357 respondents demonstrates that stigmatizing attitudes toward patients with acne existed across a variety of social and professional scenarios, with severe acne and acne in darker skin tone being associated with a greater degree of stigma. These findings highlight the need to identify approaches to reduce stigmatizing attitudes in the community and for adequate access to care, which might prevent negative downstream effects related to these stigmatizing attitudes.

Authors: John S. Barbieri, M.D., M.B.A., of Brigham and Women’s Hospital in Boston, is the corresponding author.

 

(doi:10.1001/jamadermatol.2023.4487)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

COVID-19 Rapid Antigen Tests With Self-Collected vs Health Care Worker–Collected Nasal and Throat Swab Specimens

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, DECEMBER 6, 2023

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2023.44295?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=120623

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: This randomized clinical trial found that a single health care worker-collected throat specimen had higher sensitivity for rapid antigen testing for SARS-CoV-2 than a nasal specimen. In contrast, the self-collected nasal specimens had higher sensitivity than throat specimens for symptomatic participants. Adding a throat specimen to the standard practice of collecting a single nasal specimen could improve sensitivity for rapid antigen testing in health care and home-based settings. 

Authors: Tobias Todsen, M.D., Ph.D., of Copenhagen University Hospital in Copenhagen, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.44295)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.