Long-Term Prognosis of Patients With Myocarditis Attributed to COVID-19 mRNA Vaccination, SARS-CoV-2 Infection, or Conventional Etiologies

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 3 P.M. ET, MONDAY, AUGUST 26, 2024

Media advisory: The full study is linked to this news release. This study is being presented at the 2024 International Society for Pharmacoepidemiology Annual Meeting.

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About The Study: Patients with post–COVID-19 mRNA vaccination myocarditis, contrary to those with post–COVID-19 myocarditis, show a lower frequency of cardiovascular complications than those with conventional myocarditis at 18 months. However, affected patients, mainly healthy young men, may require medical management up to several months after hospital discharge.

Corresponding Authors: To contact the corresponding authors, email Laura Semenzato, MSc (laura.semenzato@assurance-maladie.fr) and Mahmoud Zureik, MD, PhD (Mahmoud.ZUREIK@ansm.sante.fr).

 

(doi:10.1001/jama.2024.16380)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Longitudinal Changes in Youth Mental Health From Before to During the COVID-19 Pandemic

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, MONDAY, AUGUST 26, 2024

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this longitudinal cohort study of economically and racially diverse U.S. youth, there was evidence of differential susceptibility and resilience for mental health problems during the pandemic that was associated with prepandemic mental health and sociodemographic characteristics. These differences are critical to understand for recovery and may yield novel insights into causes of youth mental health problems. 

Corresponding Authors: To contact the corresponding authors, email Courtney K. Blackwell, PhD (ckblackwell@northwestern.edu) and Kaja Z. LeWinn, ScD (kaja.lewinn@ucsf.edu).

 

(doi:10.1001/jamanetworkopen.2024.30198)

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Repetitive Head Impacts and Perivascular Space Volume in Former Football Players

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, MONDAY, AUGUST 26, 2024

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this cross-sectional cohort study of 170 former football players and 54 unexposed controls, larger perivascular space (PVS) volume was associated with greater exposure to repetitive head impacts (RHI). Additionally, PVS volume was associated with worse performance on cognitive tests. These findings suggest that PVS volume may contribute to the association between exposure to RHI, cognitive impairment, and the development of RHI-associated neurodegeneration. 

Corresponding Author: To contact the corresponding author, Inga K. Koerte, MD, PhD, email ikoerte@bwh.harvard.edu.

 

(doi:10.1001/jamanetworkopen.2024.28687)

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Neighborhood-Level Disparities in Hypertension Prevalence and Treatment Among Middle-Aged Adults

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, AUGUST 23, 2024

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: Researchers found corresponding increases in hypertension prevalence as neighborhood disadvantage and the percentage of Black patients residing in a neighborhood increased in this cross-sectional study. A higher burden of midlife hypertension was identified in Black adults compared with other racial and ethnic groups that persisted across levels of socioeconomic disadvantage. This study also found that living in socioeconomically disadvantaged neighborhoods was associated with higher hypertension rates among people of all racial and ethnic backgrounds. Using spatial analysis techniques to identify neighborhoods in need, future research might investigate structural interventions to address place-based hypertension disparities. 

Corresponding Author: To contact the corresponding author, Jarrod E. Dalton, PhD, email daltonj@ccf.org.

 

(doi:10.1001/jamanetworkopen.2024.29764)

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Trends of Heat-Related Deaths in the US, 1999-2023

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 11 A.M. ET, MONDAY, AUGUST 26, 2024

Media advisory: The full study is linked to this news release.

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About The Study: This study found that heat-related mortality rates in the U.S. increased between 1999 and 2023, especially during the last 7 years. Although a study using data through 2018 found a downward trend in heat-related mortality in the U.S., this study is the first to our knowledge to demonstrate a reversal of this trend from 2016 to 2023. These results align with site-specific data analyzed in a global study that suggest increases in heat-related mortality. As temperatures continue to rise because of climate change, the recent increasing trend is likely to continue. Local authorities in high-risk areas should consider investing in the expansion of access to hydration centers and public cooling centers or other buildings with air conditioning.

Corresponding Author: To contact the corresponding author, Jeffrey T. Howard, PhD, email jeffrey.howard@utsa.edu.

 

(doi:10.1001/jama.2024.16386)

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A Screening Strategy to Mitigate Vision Impairment by Engaging Adults Who Underuse Eye Care Services

Posted by Jim Michalski

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Elinzanetant for the Treatment of Vasomotor Symptoms Associated With Menopause

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, AUGUST 22, 2024

Media advisory: The full study and editorial are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.14618?guestAccessKey=79b5ac8d-500e-4ab7-9d91-d90baedd6140&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=082224

 

About The Study: In two pivotal phase 3 clinical trials, elinzanetant, a selective neurokinin-1,3 receptor antagonist, demonstrated statistically significant reductions in vasomotor symptoms (VMS) frequency and severity vs placebo in postmenopausal individuals with moderate to severe VMS. Elinzanetant also significantly improved sleep disturbances and menopause-related quality of life vs placebo; the safety profile was favorable.

Corresponding Author: To contact the corresponding author, JoAnn V. Pinkerton, MD, MSCP, email JVP9U@uvahealth.org.

 

(doi:10.1001/jama.2024.14618)

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Disparities in Exposure to Tobacco on Television or Streaming Platforms

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, AUGUST 22, 2024

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.27781?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=082224

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this study of the prevalence of exposure to tobacco advertisements on TV or streaming platforms among U.S. adults, disparities in exposure by race or ethnicity, education level, and smoking status were identified. These findings underscore the need for targeted public health interventions and regulation to address these disparities and reduce the impact of tobacco advertisements on vulnerable populations. 

Corresponding Author: To contact the corresponding author, Sanjay Shete, PhD, email sshete@mdanderson.org.

 

(doi:10.1001/jamanetworkopen.2024.27781)

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Trends in Children’s Exposure to Food and Beverage Advertising on Television

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, AUGUST 22, 2024

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

  

About The Study: In this repeated cross-sectional study of children’s exposure to food-related television advertisements, exposure via children’s programming decreased substantially. However, most advertisements seen were still for unhealthy products, and exposure from all programming remained substantial. Findings of more than 90% of advertising exposure not from children’s programming and more than 1,000 food-related advertisements seen per year suggest the need for government regulations based on time of day rather than programming. 

Corresponding Author: To contact the corresponding author, Lisa M. Powell, PhD, email powelll@uic.edu.

 

(doi:10.1001/jamanetworkopen.2024.29671)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Virtual Learning in Kindergarten Through Grade 12 During the COVID-19 Pandemic and Chronic Absenteeism

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, AUGUST 21, 2024

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: Chronic absenteeism rates were substantially higher in school districts that used virtual learning during the COVID-19 pandemic compared with in person in this cross-sectional study. Understanding how to reduce chronic absenteeism and use virtual learning without potentially negative consequences are key policy questions moving forward. 

Corresponding Author: To contact the corresponding author, William N. Evans, PhD, email wevans1@nd.edu.

 

(doi:10.1001/jamanetworkopen.2024.29569)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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COVID-19 and Mental Illnesses in Vaccinated and Unvaccinated People

Posted by Jim Michalski

JAMA Psychiatry

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, AUGUST 21, 2024

Media advisory: The full study is linked to this news release.

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About The Study: In this cohort study, depression, serious mental illness, general anxiety, posttraumatic stress disorder, eating disorders, addiction, self-harm, and suicide were elevated during weeks 1 through 4 after COVID-19 diagnosis compared with before or without COVID-19. Incidence was lower in people who were vaccinated when they had COVID-19 and incidence was higher, and persisted longer, after hospitalization for COVID-19. The findings support recommendation of COVID-19 vaccination in the general population and particularly among those with mental illness, who may be at higher risk of both SARS-CoV-2 infection and adverse outcomes following COVID-19.

  

Quote from co-author Venexia M. Walker, PhD:

“Our findings have important implications for public health and mental health service provision, as serious mental illnesses are associated with more intensive healthcare needs and longer-term health and other adverse effects.

“Our results highlight the importance COVID-19 vaccination in the general population and particularly among those with mental illnesses, who may be at higher risk of both SARS-CoV-2 infection and adverse outcomes following COVID-19.”

 

Contact information for corresponding author Jonathan Sterne, PhD: email press-office@bristol.ac.uk.

 

(10.1001/jamapsychiatry.2024.2339)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Characterizing Long COVID in Children and Adolescents

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 12 P.M. ET, WEDNESDAY, AUGUST 21, 2024

Media advisory: The full study and editorial are linked to this news release.

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About The Study: In this large-scale study, symptoms that characterized pediatric postacute sequelae of SARS-CoV-2 infection (PASC), or long COVID, differed by age group, and several distinct phenotypic PASC presentations were described. The research indices developed here will help researchers identify children and adolescents with high likelihood of PASC. Although these indices will require further research and validation, this work provides an important step toward a clinically useful tool for diagnosis with the ultimate goal of supporting optimal care for youth with PASC.

 

Quote from corresponding author Rachel S. Gross, MD, MS:

“Our study is one of the first of its kind to characterize long COVID symptoms in children across age groups and develop a tool to help identify those who are most likely to have long COVID. This is important because there remains a common misperception that pediatric long COVID is rare, and this research can raise awareness of its impact on children.

“For this study, we looked at different groupings of symptoms across varying childhood ages and found that many of the symptoms were similar, but distinguishable from each other. Understanding why these differences occur can help inform future treatment tailored for specific age groups.”

 

Contact information for Rachel S. Gross, MD, MS: email Domonique Chaplin at Domonique.Chaplin@nyulangone.org.

 

(doi:10.1001/jama.2024.12747)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Individual- and Community-Level Risk Factors of Cancer-Related Financial Hardship Among Cancer Survivors

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, TUESDAY, AUGUST 20, 2024

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this cross-sectional study, approximately 50% of cancer survivors experienced cancer-related financial hardship, with a disproportionate number of survivors who were younger, were Medicare or Medicaid beneficiaries, were socioeconomically disadvantaged, and had advanced disease. Social vulnerability was independently associated with increasing levels of financial hardship, emphasizing the central role one’s community may play in cancer survivorship and the compounding financial detriments of residing in a socially vulnerable community. 

Corresponding Author: To contact the corresponding author, Rishi Robert Sekar, MD, MS, email rsekar@med.umich.edu.

 

(doi:10.1001/jamanetworkopen.2024.29286)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Disproportionality Analysis From World Health Organization Data on Semaglutide, Liraglutide, and Suicidality

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, TUESDAY, AUGUST 20, 2024

Media advisory: The full study and commentary are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.23385?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=082024

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this disproportionality study of an adverse drug reaction database, researchers identified a disproportionality signal of suicidal ideation with semaglutide, but not for liraglutide, particularly among patients with co-reported antidepressant use, a proxy for affective disorders (a notable exclusion criteria of premarketing clinical trials). A detected signal of semaglutide-associated suicidal ideation warrants urgent clarification. 

Corresponding Author: To contact the corresponding author, Georgios Schoretsanitis, MD, PhD, email george.schor@gmail.com.

 

(doi:10.1001/jamanetworkopen.2024.23385)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Time to Gender-Affirming Hormone Therapy Among US Military–Affiliated Adolescents and Young Adults

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapediatrics/fullarticle/10.1001/jamapediatrics.2024.2835?guestAccessKey=42c6a28e-e567-419c-a41d-e8e03a2795cd&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=081924

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Expanded Child Tax Credit and Food Insecurity

Posted by Jim Michalski

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, AUGUST 19, 2024

Media advisory: The full study is linked to this news release.  

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About The Study: Expanded Child Tax Credit (ECTC) enactment was associated with substantially lower food insecurity, and ECTC expiration was associated with substantially greater food insecurity in this cohort study. Key features of the ECTC—monthly payments and no earnings requirements—may be important for food insecurity prevention. Future studies should examine this, along with income as a potential effect modifier. 

Corresponding Author: To contact the corresponding author, Seth A. Berkowitz, MD, MPH, email seth_berkowitz@med.unc.edu.

 

(doi:10.1001/jamainternmed.2024.3972)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Telehealth Mindfulness-Based Interventions for Chronic Pain

Posted by Jim Michalski

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, AUGUST 19, 2024

Media advisory: The full study and commentary are linked to this news release.  

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/10.1001/jamainternmed.2024.3940?guestAccessKey=bc2cb3b5-b6de-44a4-a6d2-478de3d8c145&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=081924

 

About The Study: Scalable telehealth mindfulness-based interventions improved pain-related function and biopsychosocial outcomes compared to usual care among veterans with chronic pain in this randomized clinical trial. Relatively low-resource telehealth-based mindfulness-based interventions could help accelerate and improve the implementation of nonpharmacological pain treatment in health care systems.

Corresponding Author: To contact the corresponding author, Diana J. Burgess, PhD, email diana.burgess@va.gov.

 

(doi:10.1001/jamainternmed.2024.3940)

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Machine Learning Prediction of Autism Spectrum Disorder From a Minimal Set of Medical and Background Information

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, MONDAY, AUGUST 19, 2024

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.29229?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=081924

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

  

About The Study: The machine learning model developed in this study shows promise in the early identification of individuals with an elevated likelihood of autism spectrum disorder, using minimal information, which could affect early diagnosis and intervention strategies. 

Corresponding Author: To contact the corresponding author, Kristiina Tammimies, PhD, email kristiina.tammimies@ki.se.

 

(doi:10.1001/jamanetworkopen.2024.29229)

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USPSTF Statement on Screening and Supplementation for Iron Deficiency and Iron Deficiency Anemia During Pregnancy

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 10:30 A.M. (ET), TUESDAY, AUGUST 20, 2024

Media advisory: To contact the U.S. Preventive Services Task Force, email the Media Coordinator at Newsroom@USPSTF.net or call 301-951-9203. The full report and related articles are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time and all USPSTF articles remain free indefinitely https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.15196?guestAccessKey=a63aa7df-1c67-4c1c-a38f-38951a272984&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=082024

 

Bottom Line: The U.S. Preventive Services Task Force (USPSTF) concludes that the current evidence is insufficient to assess the balance of benefits and harms of screening and routine supplementation for iron deficiency and iron deficiency anemia in pregnant persons to prevent adverse maternal and infant health outcomes. Iron deficiency is the leading cause of anemia during pregnancy. According to survey data from 1999 to 2006, overall estimated prevalence of iron deficiency during pregnancy is near 18% and increases across the three trimesters of pregnancy. An estimated 5% of pregnant persons have iron deficiency anemia. The USPSTF routinely makes recommendations about the effectiveness of preventive care services and this recommendation is consistent with the 2015 recommendation statement on screening and supplementation for iron deficiency anemia during pregnancy.

 

(doi:10.1001/jama.2024.15196)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.

Note: More information about the U.S. Preventive Services Task Force, its process, and its recommendations can be found on the newsroom page of its website.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email mediarelations@jamanetwork.org.

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Florida’s Red Flag Gun Law and Firearm and Nonfirearm Homicide and Suicide Rates

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 11 A.M. ET, MONDAY, AUGUST 19, 2024

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.14465?guestAccessKey=0938d21b-12de-484b-bc99-43de7f64d8e9&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=081924

 

About The Study: Although firearm homicide mortality increased after Florida’s red flag law enactment (permitting the temporary removal of firearms by law enforcement officers from individuals posing a danger to themselves or others), this increase was lower than expected compared with its synthetic control, resulting in an 11% rate reduction (0.73 fewer deaths per 100,000). There were no differences from expected mortality rates for nonfirearm homicide, firearm suicide, or nonfirearm suicide.

Corresponding Author: To contact the corresponding author, Catherine Gimbrone, MPH, email c.gimbrone@columbia.edu.

 

(doi:10.1001/jama.2024.14465)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Perceived Parental Distraction by Technology and Mental Health Among Emerging Adolescents

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, AUGUST 16, 2024

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.28261?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=081624

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In a cohort study of 1,300 emerging adolescents ages 9 to 11 across three assessments, higher levels of anxiety symptoms were associated with higher levels of perceived parental technoference later in development. Higher levels of perceived parental technoference were associated with higher levels of inattention and hyperactivity symptoms later in development. The findings of this study speak to the need to discuss digital technology use and mental health with parents and emerging adolescents as a part of routine care. 

Corresponding Author: To contact the corresponding author, Sheri Madigan, PhD, email sheri.madigan@ucalgary.ca.

 

(doi:10.1001/jamanetworkopen.2024.28261)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

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Drug Prices After Patent Expirations in High-Income Countries and Implications for Cost-Effectiveness Analyses

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama-health-forum/fullarticle/10.1001/jamahealthforum.2024.2530?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=081624

About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

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Safety Net Primary Care Capabilities After the COVID-19 Pandemic

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama-health-forum/fullarticle/10.1001/jamahealthforum.2024.2547?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=081624

About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

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Adverse Childhood Experiences and Adult Household Firearm Ownership

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, AUGUST 15, 2024

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.28027?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=081524

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: Consistent with prior research on adverse childhood experience (ACE; defined as abuse, neglect, and household dysfunction before age 18) exposure and presence of a firearm in the household during childhood, this study found that cumulative ACE exposure was associated with higher odds of household firearm ownership in adulthood. The relationship may be due to a heightened sense of vulnerability to physical violence and greater perceived threats to personal safety associated with a traumatic childhood, which lead individuals to seek self-protection.

Corresponding Author: To contact the corresponding author, Alexander Testa, PhD, email alexander.testa@uth.tmc.edu.

 

(doi:10.1001/jamanetworkopen.2024.28027)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Uterus Transplant in Women With Absolute Uterine-Factor Infertility

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, AUGUST 15, 2024

Media advisory: The full study and editorial are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.11679?guestAccessKey=67be3d2a-3b39-4f41-953c-0f02c717d1af&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=081524

 

About The Study: Uterus transplant was technically feasible and was associated with a high live birth rate following successful graft survival. Adverse events were common, with medical and surgical risks affecting recipients as well as donors. Congenital abnormalities and developmental delays have not occurred to date in the live-born children.

Corresponding Author: To contact the corresponding author, Liza Johannesson, MD, PhD, email Liza.Johannesson@bswhealth.org.

 

(doi:10.1001/jama.2024.11679)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

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Edetate Disodium–Based Chelation for Patients With a Previous Myocardial Infarction and Diabetes

Posted by Jim Michalski

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Insurance-Related Disparities in Withdrawal of Life Support and Mortality After Spinal Cord Injury

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamasurgery/fullarticle/10.1001/jamasurg.2024.2967?guestAccessKey=ab88ef67-2847-46d7-874e-cc654e13bf50&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=081424

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State COVID-19 Vaccine Mandates and Uptake Among Health Care Workers in the US

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, AUGUST 14, 2024

Media advisory: The full study and editorial are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.26847?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=081424

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: This repeated cross-sectional study found that state COVID-19 vaccine mandates for health care workers (HCWs) were associated with increased vaccine uptake among HCWs, especially among younger HCWs and those in states with no test-out option. These findings suggest the potential for vaccine mandates to further promote vaccinations in an already highly vaccinated HCW population, especially when no test-out option is in place. 

Corresponding Author: To contact the corresponding author, Charles Stoecker, PhD, email cfstoecker@tulane.edu.

 

(doi:10.1001/jamanetworkopen.2024.26847)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Depressive Symptoms in Adolescence and Young Adulthood

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, AUGUST 14, 2024

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.27748?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=081424

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: This panel cohort study found that increases in depressive symptoms in adolescence persisted into young adulthood, suggesting the need for primary prevention and mental health resources during the adolescent years. 

Corresponding Author: To contact the corresponding author, Katherine M. Keyes, PhD, email kmk2104@columbia.edu.

 

(doi:10.1001/jamanetworkopen.2024.27748)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Leading Health-Related Concerns of Older Adults Before the 2024 Election

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, AUGUST 14, 2024

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.14353?guestAccessKey=4ff74037-8735-46f0-a62c-adddee673383&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=081424

 

About The Study: In this nationally representative survey regarding 26 prominent health-related issues, older adults reported being most concerned about costs of health care and health insurance for older adults in their community, as well as financial scams and fraud. More than half of older adults in nearly all demographic groups reported being very concerned about the costs of medical care and prescription drugs, with significant differences by gender and political ideology. Women reported being more concerned than men, and liberal and moderate individuals more concerned than conservative individuals.

Corresponding Author: To contact the corresponding author, John Z. Ayanian, MD, MPP, email ayanian@umich.edu.

 

(doi:10.1001/jama.2024.14353)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Smartwatch Measures of Outdoor Exposure and Nearsightedness in Children

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, TUESDAY, AUGUST 13, 2024

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.24595?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=081324

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

  

About The Study: In this 1-year prospective cohort study of children with smartwatches, continuous outdoor exposure with at least 15 minutes accompanied with no less than 2,000 lux sunlight intensity was associated with less myopic shift. These findings suggest that future outdoor interventions should focus not only on the overall time outdoors but also on the effective outdoor exposure patterns, as a means to effectively prevent myopia (nearsightedness) in children. 

Corresponding Authors: To contact the corresponding authors, email Xiangui He, PhD, (xianhezi@163.com) and Xun Xu, MD, (drxuxun@sjtu.edu.cn).

 

(doi:10.1001/jamanetworkopen.2024.24595)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Posttraumatic Stress Disorder and Type 2 Diabetes Outcomes in Veterans

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, TUESDAY, AUGUST 13, 2024

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.27569?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=081324

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: The findings of this cohort study of patients with comorbid posttraumatic stress disorder (PTSD) and type 2 diabetes suggest that PTSD is a modifiable risk factor associated with a modest reduction in microvascular complications. Further research is needed to determine whether findings are similar in non-Veterans Health Administration health care settings. 

Corresponding Author: To contact the corresponding author, Jeffrey F. Scherrer, PhD, email jeffrey.scherrer@health.slu.edu.

 

(doi:10.1001/jamanetworkopen.2024.27569)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Plant and Animal Fat Intake and Overall and Cardiovascular Disease Mortality

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/10.1001/jamainternmed.2024.3799?guestAccessKey=db09792f-362d-449f-b4f3-ec9c762dfce0&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=081224

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GLP-1RA vs DPP-4i Use and Rates of Hyperkalemia and RAS Blockade Discontinuation in Type 2 Diabetes

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/10.1001/jamainternmed.2024.3806?guestAccessKey=c62d1edf-d853-4984-a397-c85073571488&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=081224

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Infant Feeding and Weight Trajectories in the Eat, Sleep, Console Trial

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapediatrics/fullarticle/10.1001/jamapediatrics.2024.2578?guestAccessKey=69600d7f-e090-4fe5-b993-e348f4527cf4&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=081224

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Hospitalizations for Multisystem Inflammatory Syndrome in Children (MIS-C) in US Children’s Hospitals in 2023 vs 2021

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapediatrics/fullarticle/10.1001/jamapediatrics.2024.2882?guestAccessKey=8453ee55-8c4d-4baa-9819-cc2d2655b557&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=081224

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Early-Childhood Tablet Use and Outbursts of Anger

Posted by Jim Michalski

JAMA Pediatrics

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, AUGUST 12, 2024

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapediatrics/fullarticle/10.1001/jamapediatrics.2024.2511?guestAccessKey=c061e62c-589d-4e07-8fff-5ed9233e5c78&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=081224

 

About The Study: Child tablet use at age 3.5 years was associated with more expressions of anger and frustration by the age of 4.5 years in this study. Child proneness to anger/frustration at age 4.5 years was then associated with more use of tablets by age 5.5 years. These results suggest that early-childhood tablet use may contribute to a cycle that is deleterious for emotional regulation.

Corresponding Author: To contact the corresponding author, Caroline Fitzpatrick, PhD, email caroline.fitzpatrick@usherbrooke.ca.

 

(doi:10.1001/jamapediatrics.2024.2511)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

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Alcohol Consumption Patterns and Mortality Among Older Adults With Health-Related or Socioeconomic Risk Factors

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, MONDAY, AUGUST 12, 2024

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.24495?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=081224

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this cohort study of older drinkers from the UK, even low-risk drinking was associated with higher mortality among older adults with health-related or socioeconomic risk factors. The attenuation of mortality observed for wine preference and drinking only during meals requires further investigation, as it may mostly reflect the effect of healthier lifestyles, slower alcohol absorption, or nonalcoholic components of beverages. 

Corresponding Author: To contact the corresponding author, Rosario Ortolá, MD, PhD, email rosario.ortola@uam.es.

 

(doi:10.1001/jamanetworkopen.2024.24495)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Comparative Safety of In Utero Exposure to Buprenorphine Combined With Naloxone vs Buprenorphine Alone

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 11 A.M. ET, MONDAY, AUGUST 12, 2024

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.11501?guestAccessKey=13abe6ab-07a2-438b-aa67-5315bc3e3938&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=081224

 

About The Study: There were similar and, in some instances, more favorable neonatal and maternal outcomes for pregnancies exposed to buprenorphine combined with naloxone compared with buprenorphine alone. For the outcomes assessed, compared with buprenorphine alone, buprenorphine with naloxone during pregnancy appears to be a safe treatment option. This supports the view that both formulations are reasonable options for the treatment of opioid use disorder in pregnancy, affirming flexibility in collaborative treatment decision-making.

Corresponding Author: To contact the corresponding author, Loreen Straub, MD, MS, email lstraub@bwh.harvard.edu.

 

(doi:10.1001/jama.2024.11501)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

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Universal Free School Meals and School and Student Outcomes

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, AUGUST 9, 2024

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.24082?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=080924

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this systematic review, universal free school meals were associated with increased meal participation, no or slight improvements in attendance, and decreased obesity prevalence and suspension rates; certainty of evidence was moderate for lunch participation and low or very low for other outcomes. Studies did not report several important outcomes, such as diet quality and food security, suggesting the need for more high-quality research encompassing policy-relevant indicators. 

Corresponding Author: To contact the corresponding author, Amanda MacFarlane, PhD, email amanda.macfarlane@ag.tamu.edu.

 

(doi:10.1001/jamanetworkopen.2024.24082)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Extent of Drug Patents With Terminal Disclaimers and Obviousness-Type Double Patenting Rejections

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.14350?guestAccessKey=5b6f14b0-82da-4925-a400-8b84f3423beb&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=081224

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Neighborhood-Level Social Determinants of Health and Presenting Characteristics for Rhegmatogenous Retinal Detachments

Posted by Jim Michalski

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Leading Causes of Death in the US, 2019-2023

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 1 P.M. ET, THURSDAY, AUGUST 8, 2024

Media advisory: The full article is linked to this news release.

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About The Article: This Viewpoint from the National Center for Health Statistics reports the leading causes of death in the U.S. from 2019 to 2023, including the emergence of COVID-19 and shifts in other top causes as pandemic deaths decreased.

Corresponding Author: To contact the corresponding author, Farida Bhuiya Ahmad, MPH, email hhi0@cdc.gov.

 

(doi:10.1001/jama.2024.15563)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Oral Antibiotics and Risk of Serious Cutaneous Adverse Drug Reactions

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, AUGUST 8, 2024

Media advisory: The full study is linked to this news release.

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About The Study: Commonly prescribed oral antibiotics are associated with an increased risk of serious cutaneous adverse drug reactions compared with macrolides, with sulfonamides and cephalosporins carrying the highest risk. Prescribers should preferentially use lower-risk antibiotics when clinically appropriate.

Corresponding Author: To contact the corresponding author, David N. Juurlink, M.D., Ph.D., email david.juurlink@ices.on.ca.

 

(doi:10.1001/jama.2024.11437)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Childhood and Adolescent Depression Symptoms and Young Adult Mental Health and Psychosocial Outcomes

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, AUGUST 8, 2024

Media advisory: The full study and commentary are linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this cohort study of Canadian children and adolescents, childhood and adolescent depression symptoms were associated with impaired adult psychosocial functioning. Interventions should aim to screen and monitor children and adolescents for depression to inform policymaking regarding young adult mental health and psychosocial outcomes. 

Corresponding Author: To contact the corresponding author, Marilyn N. Ahun, PhD, email marilyn.ahun@mcgill.ca.

 

(doi:10.1001/jamanetworkopen.2024.25987)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Cannabis Use and Head and Neck Cancer

Posted by Jim Michalski

JAMA Otolaryngology–Head & Neck Surgery

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, AUGUST 8, 2024

Media advisory: The full study and commentary are linked to this news release.

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About The Study: This cohort study highlights an association between cannabis-related disorder and the development of head and neck cancer in adult patients. Given the limitations of the database, future research should examine the mechanism of this association and analyze dose response with strong controls to further support evidence of cannabis use as a risk factor for head and neck cancers. 

Corresponding Author: To contact the corresponding author, Niels C. Kokot, MD, email niels.kokot@med.usc.edu.

 

(doi:10.1001/jamaoto.2024.2419)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Neighborhood Socioeconomic Disadvantage Across the Life Course and Premature Mortality

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, AUGUST 7, 2024

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: Low neighborhood socioeconomic status was associated with premature mortality in this study. The risk of premature mortality was greatest among individuals experiencing persistently low neighborhood socioeconomic status from young to middle adulthood. Place-based interventions that target neighborhood social determinants of health should be designed from a life course perspective that accounts for early-life socioeconomic inequality. 

Corresponding Author: To contact the corresponding author, Wayne R. Lawrence, DrPH, email wayne.lawrence@nih.gov.

 

(doi:10.1001/jamanetworkopen.2024.26243)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Rates of Sudden Death After Myocardial Infarction— Insights From the VALIANT and PARADISE-MI Trials

Posted by Jim Michalski

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Primary Care Use and 90-Day Mortality Among Older Adults Undergoing Cancer Surgery

Posted by Jim Michalski

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Controversial FDA Decision Authorizes Menthol-Flavored E-Cigarettes Despite Risks to Youth

Posted by Jim Michalski

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Variability in Constituents of E-Cigarette Products Containing Nicotine Analogues

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, AUGUST 7, 2024

Media advisory: The full study is linked to this news release.

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About The Study: Discrepancies were observed between labeled and measured concentrations of nicotine analogues in e-cigarettes and e-cigarette liquids marketed as nicotine replacements and exempt from FDA’s regulatory purview. Such discrepancies may lead to uncertainty about user exposure. When coupled with the largely unknown acute and chronic inhalation hazards and addictive potential of nicotine analogues, assessing product risk based on exposure becomes challenging from a clinical and regulatory standpoint. With e-cigarettes increasingly considered for smoking cessation, the advent of nicotine analogue–containing products with unknown health risks raises concern.

Corresponding Author: To contact the corresponding author, Sven E. Jordt, PhD, email sven.jordt@duke.edu.

 

(doi:10.1001/jama.2024.12408)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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A Vaping Cessation Text Message Program for Adolescent E-Cigarette Users

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, AUGUST 7, 2024

Media advisory: The full study and editorial are linked to this news release.

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About The Study: A tailored, interactive text message intervention increased self-reported vaping cessation rates among adolescents recruited via social media channels.

Quote from corresponding author Amanda L. Graham, PhD:

“Health care providers, teachers, and parents have been asking how to help teens quit vaping. This study is a critical breakthrough that demonstrates the power of a behavioral intervention for vaping cessation. Text messages serve as powerful reminders of an initial commitment to quit and can deliver proven behavior change support right to a young person’s phone.

“We also did not see evidence that teens who quit vaping transitioned to smoking. The intervention was effective in reducing dual use (smoking and vaping) and keeping teens in this study from starting to smoke.”

 

Contact information for Amanda L. Graham, PhD: email Megan Kelley (mkelley@truthinitiative.org).

 

(doi:10.1001/jama.2024.11057)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Demographic Representation of Generative AI Images of Physicians

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, TUESDAY, AUGUST 6, 2024

Media advisory: The full study and commentary are linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: This study identifies demographic biases in artificial intelligence (AI)-generated images of physicians with disproportionate representation of white and male physicians and concerning underrepresentation of other races and ethnicities (Asian and Latino) and female physicians in some platforms. This bias has the potential to reinforce stereotypes and undermine diversity, equity, and inclusion initiatives within health care. 

Corresponding Author: To contact the corresponding author, Sang Won Lee, MSc, email sangwon_lee@hms.harvard.edu.

 

(doi:10.1001/jamanetworkopen.2024.25993)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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AI for Early Detection of Pediatric Eye Diseases Using Mobile Photos

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, TUESDAY, AUGUST 6, 2024

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this cross-sectional study, the artificial intelligence (AI) model demonstrated strong performance in accurately identifying myopia, strabismus, and ptosis using only smartphone images. These results suggest that such a model could facilitate the early detection of pediatric eye diseases in a convenient manner at home.

Corresponding Authors: To contact the corresponding authors, email Lin Li, MD, PhD (jannetlee130@gmail.com), and Jie Xu, DHM (xujie@pjlab.org.cn).

 

(doi:10.1001/jamanetworkopen.2024.25124)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Type 2 Diabetes and Fracture Risk in Older Women

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, TUESDAY, AUGUST 6, 2024

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: The results from this study suggest that the higher fracture risk among older women with type 2 diabetes may be due to impaired physical function and not skeletal characteristics. 

Corresponding Author: To contact the corresponding author, Mattias Lorentzon, MD, PhD, email mattias.lorentzon@medic.gu.se.

 

(doi:10.1001/jamanetworkopen.2024.25106)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Estimated Exposure to 6 Potentially Hepatotoxic Botanicals in US Adults

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, MONDAY, AUGUST 5, 2024

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.25822?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=080524

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this survey study, an estimated 15.6 million U.S. adults consumed at least one botanical product with liver liability within the past 30 days, comparable with the number of people who consumed nonsteroidal anti-inflammatory drugs and a commonly prescribed hypolipidemic drug. Turmeric was most frequently reported, followed in order by green tea, ashwagandha, Garcinia cambogia, red yeast rice, and black cohosh products.  Given a lack of regulatory oversight on the manufacturing and testing of botanical products, clinicians should be aware of possible adverse events from consumption of these largely unregulated products. 

Corresponding Author: To contact the corresponding author, Alisa Likhitsup, MD, MPH, email allikhit@med.umich.edu.

 

(doi:10.1001/jamanetworkopen.2024.25822)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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COVID-19 Pandemic School Disruptions and Acute Mental Health in Children and Adolescents

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, MONDAY, AUGUST 5, 2024

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.25829?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=080524

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this cross-sectional study of 13,000 pediatric emergency department visits at nine university hospitals in Italy, school opening following a COVID-19 pandemic–related school disruption was associated with an increase in acute psychiatric emergencies. The findings of this study suggest that school may be a major source of stress for youths; factors mediating school-associated mental health disturbances in youth should be investigated. 

Corresponding Author: To contact the corresponding author, Benedetto Vitiello, MD, email benedetto.vitiello@unito.it.

 

(doi:10.1001/jamanetworkopen.2024.25829)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Health, Access to Care, and Financial Barriers to Care Among People Incarcerated in US Prisons

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/10.1001/jamainternmed.2024.3567?guestAccessKey=e4d5a49b-232b-477a-96d8-b7720f9bbb54&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=080524

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