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Young-Onset Dementia Among Individuals With History of Preeclampsia
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COVID-19 Vaccination and Cardiopulmonary Events After Acute Coronary Syndromes
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, MAY 30, 2024
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.13946?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=053024
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this secondary analysis of a randomized clinical trial, patients who received at least one COVID-19 vaccine dose after acute coronary syndromes had similar rates of the primary composite end point and major adverse cardiovascular events (MACE) compared with unvaccinated patients. However, retrospective studies have demonstrated a short-term reduction in MACE risk after COVID-19 vaccination.
Corresponding Author: To contact the corresponding author, Henrique Andrade R. Fonseca, Ph.D., email henrique.fonseca@einstein.br.
(doi:10.1001/jamanetworkopen.2024.13946)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Trends in Diagnosed PTSD and Acute Stress Disorder in College Students
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, MAY 30, 2024
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.13874?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=053024
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this serial cross-sectional study including a national sample of U.S. college students, researchers found a notable increase in the prevalence of posttraumatic stress disorder (PTSD) and acute stress disorder, rising by 4.1 percentage points and 0.5 percentage points from 2017 to 2022, respectively. These trends highlight the escalating mental health challenges among college students, which is consistent with recent research reporting a surge in psychiatric diagnoses. Factors contributing to this rise may include pandemic-related stressors (e.g., loss of loved ones) and the effect of traumatic events (e.g., campus shootings, racial trauma).
Corresponding Author: To contact the corresponding author, Yusen Zhai, Ph.D., email yzhai@uab.edu.
(doi:10.1001/jamanetworkopen.2024.13874)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Long-Term Outcomes in Patients Using Protocol-Directed Active Surveillance for Prostate Cancer
JAMA
EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, MAY 30, 2024
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.6695?guestAccessKey=eb10ccd7-9ab0-4ae2-894d-978a28e0451f&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=053024
About The Study: In this study, 10 years after diagnosis, 49% of men remained free of progression or treatment, less than 2% developed metastatic disease, and less than 1% died of their disease. Later progression and treatment during surveillance were not associated with worse outcomes. These results demonstrate active surveillance as an effective management strategy for patients diagnosed with favorable-risk prostate cancer.
Quote from corresponding author Lisa F. Newcomb, Ph.D.:
“Our study showed that using active surveillance that includes regular PSA exams and prostate biopsies is a safe and effective management strategy for favorable risk prostate cancer.
“An important finding was that adverse outcomes such as recurrence or metastasis do not seem worse in people treated after several years of surveillance versus one year of surveillance, alleviating concern about losing a window of curability.
“We hope that this study encourages the national acceptance of active surveillance instead of immediate treatment for prostate cancer.”
Contact information for Lisa F. Newcomb, Ph.D.: email Kat Wynn at kwynn@fredhutch.org.
(doi:10.1001/jama.2024.6695)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Menarche and Time to Cycle Regularity Among Individuals Born Between 1950 and 2005 in the US
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Domain-Specific Physical Activity and Stroke in Sweden
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Revisiting Race and the Benefit of RAS Blockade in Heart Failure
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Isotretinoin for Acne in Transgender and Gender-Diverse Individuals Receiving Masculinizing Hormone Therapy
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Adolescent and Adult Transitions From Major Depressive Disorder to Bipolar Disorder
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Ransomware Attacks, ED Visits and Inpatient Admissions in Targeted and Nearby Hospitals
JAMA
EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, MAY 29, 2024
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.7752?guestAccessKey=387346ff-a796-48f0-bdc9-b3d2fcccde6c&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=052924
About The Study: This study found a temporary decrease in emergency department (ED) visits and inpatient admissions in hospitals targeted by ransomware attacks and a temporary increase in ED visits in unattacked nearby hospitals in California, suggesting that the consequences of such attacks are broader than the targeted hospitals.
Corresponding Author: To contact the corresponding author, Rahi Abouk, Ph.D., email aboukr@wpunj.edu.
(doi:10.1001/jama.2024.7752)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Sweetened Beverage Tax Implementation and Change in Body Mass Index Among Children in Seattle
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, MAY 29, 2024
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.13644?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=052924
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The results of this study suggest that the sweetened beverage tax in Seattle may be associated with a small but reasonable reduction in body mass index (BMI) among children living in Seattle compared with children living in nearby nontaxed areas who were receiving care within the same health care systems. Taken together with existing studies in the U.S., these results suggest that sweetened beverage taxes may be an effective policy for improving children’s BMI. Future research should test this association using longitudinal data in other U.S. cities with sweetened beverage taxes.
Corresponding Author: To contact the corresponding author, Jessica C. Jones-Smith, Ph.D., email jjoness@uw.edu.
(doi:10.1001/jamanetworkopen.2024.13644)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Abortion Provision and Delays to Care in a Clinic Network in Washington State After Dobbs
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, MAY 29, 2024
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.13847?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=052924
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The findings of this study provide a detailed picture of changes in abortion provision and delays to care after Dobbs in a state bordering a total ban state. In this study, more people traveled from out of state to receive care and in-state patients sought care a week later in gestation. These findings can inform interventions and policies to improve access for all seeking abortion care.
Corresponding Author: To contact the corresponding author, Taylor Riley, Ph.D., M.P.H., email striley@uw.edu.
(doi:10.1001/jamanetworkopen.2024.13847)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Algorithmic Content Recommendations on a Video-Sharing Platform Used by Children
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, MAY 29, 2024
Media advisory: The full study is linked to this news release.
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this study of video recommendations for search terms popular with children, thumbnails contained problematic and attention-capturing designs including violent, stereotyped, and frightening themes. Research is needed to understand how children respond to thumbnail designs and whether such designs influence the quality of content children consume.
Corresponding Author: To contact the corresponding author, Jenny Radesky, M.D., email jradesky@med.umich.edu.
(doi:10.1001/jamanetworkopen.2024.13855)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Mobile Mindfulness Intervention for Psychological Distress Among Intensive Care Unit Survivors
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Household Water Lead and Hematologic Toxic Effects in Chronic Kidney Disease
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Early-Life Circumstances and Racial Disparities in Cognition Among Older Adults in the US
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Patterns of Adverse Childhood Experiences and Neurocognitive Development
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Prenatal Magnesium Sulfate and Functional Connectivity in Offspring at Term-Equivalent Age
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Financial Burden of Health Care in the Privately Insured US Population
JAMA Internal Medicine
EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, MAY 28, 2024
Media advisory: The full study and editor’s note are linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/10.1001/jamainternmed.2024.1464?guestAccessKey=501f4b1f-d0e4-4a58-88e7-aa38973a9655&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=052824
About The Study: In this national cross-sectional study of privately insured U.S. families, inflation-adjusted health care spending increased from 2007 to 2019, largely owing to increasing contributions to premiums. Annual financial medical burden increased significantly, both overall and among low-income and higher-income families. Mean financial medical burden was more than 26% of postsubsistence income for low-income families, compared with approximately 6% for higher-income families.
Corresponding Author: To contact the corresponding author, Rishi K. Wadhera, M.D., M.P.P., M.Phil., email rwadhera@bidmc.harvard.edu.
(doi:10.1001/jamainternmed.2024.1464)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Early vs Late Anticoagulation in Minor, Moderate, and Major Ischemic Stroke With Atrial Fibrillation
JAMA Neurology
EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, MAY 28, 2024
Media advisory: The full study is linked to this news release.
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About The Study: The treatment effect of early direct oral anticoagulant initiation did not differ in people with minor, moderate, or major stroke assessed by brain imaging. Early treatment was not associated with a higher rate of adverse events, especially symptomatic intracranial hemorrhage, for any infarct size, including major stroke.
Corresponding Author: To contact the corresponding author, Urs Fischer, M.D., M.Sc., email urs.fischer@insel.ch.
(doi:10.1001/jamaneurol.2024.1450)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Air and Noise Pollution Exposure in Early Life and Mental Health From Adolescence to Young Adulthood
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. ET, TUESDAY, MAY 28, 2024
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.12169?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=052824
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: Early-life air and noise pollution exposure were prospectively associated with three common mental health problems (psychotic experiences, depression, and anxiety) from adolescence to young adulthood in this longitudinal cohort study. There was a degree of specificity in terms of pollutant-timing-outcome associations. Interventions to reduce air and noise pollution exposure (e.g., clean air zones) could potentially improve population mental health. Replication using quasi-experimental designs is now needed to shed further light on the underlying causes of these associations.
Corresponding Author: To contact the corresponding author, Joanne B. Newbury, Ph.D., email joanne.newbury@bristol.ac.uk.
(doi:10.1001/jamanetworkopen.2024.12169)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Mortality Risk Among Women With Premenstrual Disorders in Sweden
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. ET, TUESDAY, MAY 28, 2024
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.13394?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=052824
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The findings of this matched cohort study suggest that women with premenstrual disorders are not at increased risk of early death overall. However, the risk was elevated among young women and for death by suicide. This supports the importance of careful follow-up for young patients and highlights the need to develop suicide prevention strategies for all women with premenstrual disorders.
Corresponding Author: To contact the corresponding author, Marion Opatowski, Ph.D., email marion.opatowski@ki.se.
(doi:10.1001/jamanetworkopen.2024.13394)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Trust and 2024 Public Priorities for the CDC and State Health Departments
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About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
Exercise and Pain Neuroscience Education for Patients With Chronic Pain After Total Knee Arthroplasty
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Red Flag Signs and Symptoms for Patients With Early-Onset Colorectal Cancer
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GLP-1 Receptor Agonist Discontinuation Among Patients With Obesity and/or Type 2 Diabetes
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Preterm and Early-Term Delivery After Heat Waves in 50 US Metropolitan Areas
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, MAY 24, 2024
Media advisory: The full study and commentary are linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.12055?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=052424
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: Preterm and early-term birth rates increased after heat waves, particularly among socioeconomically disadvantaged subgroups in this cohort study. Extreme heat events have implications for perinatal health.
Corresponding Author: To contact the corresponding author, Lyndsey A. Darrow, Ph.D., email ldarrow@unr.edu.
(doi:10.1001/jamanetworkopen.2024.12055)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Sociodemographic Heterogeneity in the Associations of Social Isolation With Mortality
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, MAY 24, 2024
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.13132?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=052424
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: Social isolation was associated with increased risks of all-cause, cardiovascular diseases, and malignant neoplasm mortality, with associations varying across populations. This study fills an important gap in research on social isolation, emphasizing its varied associations across demographic and socioeconomic groups.
Corresponding Author: To contact the corresponding author, Atsushi Nakagomi, M.D., Ph.D., email anakagomi0211@gmail.com.
(doi:10.1001/jamanetworkopen.2024.13132)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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COVID-19 Admission Rates and Changes in Care Quality in US Hospitals
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, MAY 24, 2024
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.13127?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=052424
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this cross-sectional study, COVID-19 surges were associated with declines in hospital quality, highlighting the importance of identifying and implementing strategies to maintain care quality during periods of high hospital use.
Corresponding Author: To contact the corresponding author, Giacomo Meille, Ph.D., email giacomo.meille@ahrq.hhs.gov.
(doi:10.1001/jamanetworkopen.2024.13127)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.
SARS-CoV-2 Viral Load in the Nasopharynx at Time of First Infection Among Unvaccinated Individuals
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Coaches Activating, Reaching, and Engaging Patients to Engage in Advance Care Planning
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Mandibular Advancement vs Combined Airway and Positional Therapy for Snoring
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Accuracy of Salivary Circulating Tumor Human Papillomavirus DNA in Detecting Oropharyngeal Cancer
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Early Access to First-Seizure Clinics, Subsequent Outcomes, and Factors Associated With Attendance
JAMA Neurology
EMBARGOED FOR RELEASE: 2:30 A.M. (ET), THURSDAY, MAY 23, 2024
Media advisory: The full study is linked to this news release. This study is being released to coincide with presentation at the Australian and New Zealand Association of Neurologists Annual Scientific Meeting.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaneurology/fullarticle/10.1001/jamaneurol.2024.1187?guestAccessKey=0fbbf434-5941-4e22-a91b-dc873a3edbd1&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=052324
About The Study: The results of this cohort study suggest that first-seizure clinic (FSC) attendance, particularly early attendance, was associated with reduced rates of subsequent hospital utilization. This knowledge may support adequately resourcing FSCs to improve equitable, timely access. Future study directions include assessing interventions that may support FSC attendance for at-risk groups.
Corresponding Author: To contact the corresponding author, Emma Foster, M.B.B.S.(Hons), Ph.D., email emma.foster@monash.edu.
(doi:10.1001/jamaneurol.2024.1187)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.
Hypertension and Kidney Function After Living Kidney Donation
JAMA
EMBARGOED FOR RELEASE: 10 A.M. ET, THURSDAY, MAY 23, 2024
Media advisory: The full study and editorial are linked to this news release.
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About The Study: In this cohort study of living kidney donors and nondonors with the same follow-up schedule, the risks of hypertension and albuminuria were not significantly different. After the initial drop in estimated glomerular filtration rate (eGFR) from nephrectomy, donors had a slower mean rate of eGFR decline than nondonors but were more likely to have an eGFR between 30 and 60 mL/min/1.73 m2 at least once in follow-up.
Corresponding Author: To contact the corresponding author, Amit X. Garg, M.D., Ph.D., email amit.garg@lhsc.on.ca.
(doi:10.1001/jama.2024.8523)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Kidney Transplant Outcomes From Deceased Donors Who Received Dialysis
JAMA
EMBARGOED FOR RELEASE: 10 A.M. ET, THURSDAY, MAY 23, 2024
Media advisory: The full study and editorial are linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.8469?guestAccessKey=5db76752-4749-4731-9667-2ebd281f6edb&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=052324
About The Study: Compared with receiving a kidney from a deceased donor who did not undergo dialysis, receiving a kidney from a deceased donor who underwent dialysis prior to kidney donation was associated with a significantly higher incidence of delayed graft function, but no significant difference in graft failure or death at follow-up.
Corresponding Author: To contact the corresponding author, Chirag R. Parikh, M.D., Ph.D., email chirag.parikh@jhmi.edu.
(doi:10.1001/jama.2024.8469)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Effectiveness of a School- and Primary Care–Based HPV Vaccination Intervention
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, MAY 23, 2024
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.11938?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=052324
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this cluster randomized trial, within the context of the late COVID-19 pandemic period and limited school and general practitioner participation, at-school human papillomavirus (HPV) vaccination significantly increased vaccination coverage. The trial did not show a significant effect for training general practitioners and education and motivation, although it may be observed after more time has elapsed after the intervention.
Corresponding Author: To contact the corresponding author, Morgane Michel, Ph.D., email morgane.michel@aphp.fr.
(doi:10.1001/jamanetworkopen.2024.11938)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Prenatal Exposure to Chemical Mixtures and Metabolic Syndrome Risk in Children
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, MAY 23, 2024
Media advisory: The full study and commentary are linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.12040?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=052324
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The findings of this cohort study suggest that prenatal exposure to endocrine-disrupting chemical mixtures may be associated with adverse metabolic health in children. Given the pervasive nature of endocrine-disrupting chemicals and the increase in metabolic syndrome, these findings hold substantial public health implications.
Corresponding Author: To contact the corresponding author, Martine Vrijheid, Ph.D., email martine.vrijheid@isglobal.org.
(doi:10.1001/jamanetworkopen.2024.12040)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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US Public Health Preparedness and Response to Highly Pathogenic Avian Influenza A(H5N1) Viruses
JAMA
EMBARGOED FOR RELEASE: 12 P.M. ET, TUESDAY, MAY 21, 2024
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.10116?guestAccessKey=97235608-3017-4f2a-b30c-8486923bab25&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=052124
About The Study: Public health authorities in nearly all states and territories surveyed reported the ability to monitor and test persons exposed to highly pathogenic avian influenza (HPAI) A(H5N1) virus. However, jurisdictions varied in their capacity to monitor exposed persons, in recommendations for use of antivirals, and in potential use of H5N1 vaccines, if available, among first responders.
Quote from co-author Tim Uyeki, M.D., M.P.H., M.P.P.:
“Public and animal health experts and agencies have been preparing for avian influenza outbreaks for 20 years. We have invested in our ability to mitigate risk by testing, preventing, and treating it.
“The challenges reported in monitoring exposed persons and differences in antiviral recommendations highlight a need to continue to strengthen and standardize public health preparedness and response to HPAI A(H5N1) viruses in the United States, particularly if additional animal-to-human transmission events are reported. It’s important that as the situation develops, public health agencies and authorities continue to work together to guide process improvements to ensure preparedness and consistency in response to future exposures.”
Contact information for Tim Uyeki, M.D., M.P.H., M.P.P.: email Jasmine Reed at jreed@cdc.gov
(doi:10.1001/jama.2024.10116)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.
Patterns of Melatonin Use in a Diverse National Pediatric Sample
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Parental E-Cigarette Use and Pediatric Atopic Dermatitis
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Evaluating Firearm Violence After New Jersey’s Cash Bail Reform
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Trajectories of Gender Identity and Depressive Symptoms in Youths
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Assessing the Risk of Bias in Randomized Clinical Trials With Large Language Models
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Use of AI Chatbots in Interpretation of Pathology Reports
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Transmission of Mental Disorders in Adolescent Peer Networks
JAMA Psychiatry
EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, MAY 22, 2024
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapsychiatry/fullarticle/10.1001/jamapsychiatry.2024.1126?guestAccessKey=77db5a33-85ba-4b33-b47f-d704d07709bd&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=052224
About The Study: The findings of this study suggest that mental disorders might be transmitted within adolescent peer networks. More research is required to elucidate the mechanisms underlying the possible transmission of mental disorders.
Corresponding Author: To contact the corresponding author, Jussi Alho, Ph.D., email jussi.alho@helsinki.fi.
(10.1001/jamapsychiatry.2024.1126)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.
Firearm Homicide Demographics Before and After the COVID-19 Pandemic
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, MAY 22, 2024
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.12946?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=052224
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this study, death by firearm homicide was concentrated among Black individuals ages 15 to 24 before, during, and subsequent to the COVID-19 pandemic, implying that there are likely to be social and structural conditions that contribute to these racial disparities.
Corresponding Author: To contact the corresponding author, Alex R. Piquero, Ph.D., email axp1954@miami.edu.
(doi:10.1001/jamanetworkopen.2024.12946)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Dispensing of Glucagon-Like Peptide-1 Receptor Agonists to Adolescents and Young Adults
JAMA
EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, MAY 22, 2024
Media advisory: The full study is linked to this news release.
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About The Study: Between 2020 and 2023, the number of adolescents and young adults with glucagon-like peptide-1 receptor agonist (GLP-1RA) dispensing increased substantially. In contrast, the number with dispensing of other drugs decreased. Increases in GLP-1RA dispensing were greatest for females, highlighting the importance of educating patients and prescribers on sex-specific safety risks (e.g., concerns during pregnancy).
Quote from corresponding author Joyce M. Lee, M.D., M.P.H.:
“Little is known about the use of GLP-1 RA medications like Wegovy or Ozempic in younger patients. We found that there was a 594% increase in GLP-1 RA medication dispensing between 2020-2023 among adolescents and young adults, highlighting the importance of studying the long-term safety and effectiveness of these medications.
“Increases in GLP-1RA dispensing were more pronounced among females than among males. In 2023, 60.0% of adolescents, and 76.4% of young adults dispensed medications were female. This disproportionate dispensing may represent a societal bias towards weight in females and may have implications for the long-term health of girls and women.”
Contact information for Joyce M. Lee, M.D., M.P.H.: email joyclee@med.umich.edu.
(doi:10.1001/jama.2024.7112)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Primary Care–Based Weight Navigation Program
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Racial and Ethnic Disparities in COVID-19 Mortality
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Medicare Coverage and Patient Out-of-Pocket Costs for Cardiovascular-Kidney-Metabolic Medications
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Socioeconomic Status Transition Throughout Life and Risk of Dementia
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. ET, TUESDAY, MAY 21, 2024
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.12303?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=052124
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: This cohort study of Japanese older adults identified that upward and downward socioeconomic status transitions were associated with risk of dementia and the length of dementia-free periods over the lifespan. The results may be useful to understand the association between social mobility and healthy longevity.
Corresponding Author: To contact the corresponding author, Hiroyasu Iso, Ph.D., email iso@pbhel.med.osaka-u.ac.jp.
(doi:10.1001/jamanetworkopen.2024.12303)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Maternal Urinary Fluoride and Child Neurobehavior at Age 36 Months
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Time- vs Step-Based Physical Activity Metrics for Health
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Edible Cannabis Legalization and Cannabis Poisonings in Older Adults
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Variations by State in Firearm Suicide Among US Children and Young Adults, 2016-2021
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Bisoprolol in Patients With COPD at High Risk of Exacerbation
JAMA
EMBARGOED FOR RELEASE: 9 A.M. ET, SUNDAY, MAY 19, 2024
Media advisory: The full study and editorial are linked to this news release. This study is being presented at the American Thoracic Society 2024 International Conference.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.8771?guestAccessKey=d4543ce8-c594-44e0-805b-44a020c965ab&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=051924
About The Study: Among people with chronic obstructive pulmonary disease (COPD) at high risk of exacerbation, treatment with the β1-selective β-blocker bisoprolol did not reduce the number of self-reported COPD exacerbations requiring treatment with oral corticosteroids, antibiotics, or both.
Quote from corresponding author Graham Devereux, M.D.:
“People with COPD are at increased risk of cardiovascular conditions that benefit from treatment with beta-blockers. However, there is a well-documented reluctance for physicians to prescribe beta-blockers for people with cardiovascular disease and COPD.
“These findings will help physicians and patients with COPD assess the risks and benefits of using bisoprolol to treat cardiovascular disease.”
Contact information for Graham Devereux, M.D.: email graham.devereux@lstmed.ac.uk.
(doi:10.1001/jama.2024.8771)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Acetaminophen for Prevention and Treatment of Organ Dysfunction in Critically Ill Patients With Sepsis
JAMA
EMBARGOED FOR RELEASE: 9 A.M. ET, SUNDAY, MAY 19, 2024
Media advisory: The full study is linked to this news release. This study is being presented at the American Thoracic Society 2024 International Conference.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.8772?guestAccessKey=1b8c1ae9-3edc-4366-be12-3cf2610d148d&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=051924
About The Study: In critically ill sepsis patients, treatment with intravenous acetaminophen for 5 days was safe but did not improve the primary end point of days alive and free of any organ support (dialysis, assisted ventilation, and vasopressors) to day 28 compared with placebo.
Corresponding Author: To contact the corresponding author, Lorraine B. Ware, M.D., email Lorraine.ware@vumc.org.
(doi:10.1001/jama.2024.8772)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Survival Benefit Associated With Participation in Clinical Trials of Anticancer Drugs
JAMA
EMBARGOED FOR RELEASE: 10 A.M. ET, MONDAY, MAY 20, 2024
Media advisory: The full study, editorial and Viewpoint are linked to this news release. This study is being released to coincide with presentation at the Society for Clinical Trials Annual Meeting.
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About The Study: Many studies suggest a survival benefit for cancer trial participants. However, these benefits were not detected in studies using designs addressing important sources of bias and confounding. Pooled results of high-quality studies are not consistent with a beneficial effect of trial participation on its own.
Quote from corresponding author Jonathan Kimmelman, Ph.D.:
“Many physicians, policymakers, patient advocates, and research sponsors believe patients have better outcomes when they participate in trials, even if they are in the comparator arm. Educational materials for patients often encourage patients to consider the better care they might receive in trials. As a member of various review committees, I hear this said all the time. Yet evidence of such a ‘participation effect’ is lacking.
“Many studies have looked at the ‘participation effect’ for patients with cancer. If you pool them altogether, it looks like cancer patients in trials do live longer than patients outside them. But if you restrict analysis to studies that control for various sources of confound (for example, the fact that trials tend to enroll younger and healthier patients) or bias (many studies of participation benefit are probably never published) those survival benefits disappear.
“Our findings provide reassurance that inability to enroll in a cancer trial doesn’t disadvantage a patient, at least in terms of survival. Our findings can help patients (and physicians) focus their consent discussions on the most relevant and evidence-based benefits of trial participation: the prospects of advancing the care of future patients.”
Contact information for Jonathan Kimmelman, Ph.D.: email jonathan.kimmelman@mcgill.ca.
(doi:10.1001/jama.2024.6281)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Effect of Sleep Restriction on Adolescent Cognition by Adiposity
JAMA Neurology
EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, MAY 20, 2024
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaneurology/fullarticle/10.1001/jamaneurol.2024.1332?guestAccessKey=e6f39acb-146d-41ad-b9ae-5f7000613f06
About The Study: Adolescents with overweight or obesity may be more vulnerable to negative cognitive effects following sleep restriction. Improved sleep hygiene and duration in this group may positively impact their cognitive health.
Corresponding Author: To contact the corresponding author, Aaron D. Fobian, Ph.D., email afobian@uabmc.edu.
(doi:10.1001/jamaneurol.2024.1332)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Pamrevlumab for Idiopathic Pulmonary Fibrosis
JAMA
EMBARGOED FOR RELEASE: 9 A.M. ET, SUNDAY, MAY 19, 2024
Media advisory: The full study and editorial are linked to this news release. This study is being presented at the American Thoracic Society 2024 International Conference.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.8693?guestAccessKey=822f31af-46d7-4bed-b18f-275b80c4c704&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=051924
About The Study: Among patients with idiopathic pulmonary fibrosis treated with pamrevlumab (a fully human monoclonal antibody that binds to and inhibits connective tissue growth factor activity) or placebo, there was no statistically significant between-group difference for the primary outcome of absolute change in forced vital capacity from baseline to week 48.
Quote from corresponding author, Ganesh Raghu, M.D.:
“Current treatment with the two drugs approved by regulatory agencies for the treatment of idiopathic pulmonary fibrosis (IPF) merely slow the rate of lung function decline and are associated with adverse events that affect medication adherence. Because of the high mortality rates that are associated with IPF, the need for efficacious treatments that meaningfully improve patients’ feeling and function, as well as survival, is evident and unmet.
“This well-conducted, multinational phase 3 trial undertaken to assess the efficacy and safety of pamrevlumab for patients with IPF failed to confirm it. Despite the disappointment with the negative results, the success lies in the patients who participated in this trial and adhered to the protocol amid all the challenges and hurdles of the COVID-19 pandemic and lessons gleaned will help better design of future trials.”
Contact information for Ganesh Raghu, M.D.: email graghu@uw.edu.
(doi:10.1001/jama.2024.8693)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Racial and Ethnic Inequities in Cancer Care Continuity During the COVID-19 Pandemic Among Those With SARS-CoV-2
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. ET, MONDAY, MAY 20, 2024
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.12050?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=052024
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this cross-sectional study of patients with cancer and SARS-CoV-2, racial and ethnic inequities existed in treatment delays and discontinuations throughout the pandemic; however, the disproportionate burden among racially and ethnically minoritized patients with cancer varied across SARS-CoV-2 waves. These inequities may lead to downstream adverse impacts on cancer mortality among minoritized adults in the United States.
Corresponding Author: To contact the corresponding author, Jessica Y. Islam, Ph.D., M.P.H., email jessica.islam@moffitt.org.
(doi:10.1001/jamanetworkopen.2024.12050)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Use of Electronic Nicotine Delivery Systems and Age of Asthma Onset Among Adults and Youths
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.10740?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=051724
A Comparison of Ukrainian Hospital Services and Functions Before and During the Russia-Ukraine War
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama-health-forum/fullarticle/10.1001/jamahealthforum.2024.0901?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=051724
About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
Measuring Primary Care Spending in the US by State
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama-health-forum/fullarticle/10.1001/jamahealthforum.2024.0913?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=051724
About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
Ultraprocessed Food Consumption and Cardiometabolic Risk Factors in Children
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, MAY 17, 2024
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.11852?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=051724
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The findings of this study suggest that high ultraprocessed food (UPF) consumption in young children is associated with adiposity and other cardiometabolic risk factors, highlighting the need for public health initiatives to promote the replacement of UPFs with unprocessed or minimally processed foods.
Corresponding Author: To contact the corresponding author, Nancy Babio, Ph.D., email nancy.babio@urv.cat.
(doi:10.1001/jamanetworkopen.2024.11852)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Oropharyngeal Cancer Staging Health Record Extraction Using AI
JAMA Otolaryngology–Head & Neck Surgery
EMBARGOED FOR RELEASE: 4:15 P.M. (ET), THURSDAY, MAY 16, 2024
Media advisory: The full study is linked to this news release. This study is being released to coincide with presentation at the American Head And Neck Society Annual Meeting at Combined Otolaryngology Spring Meetings 2024.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaotolaryngology/fullarticle/10.1001/jamaoto.2023.1201?guestAccessKey=d00c9284-3b48-4557-9d6f-7f4450d46156&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=051624
About The Study: The results of this study suggest that artificial intelligence may be associated with enhanced patient care and oncological decision-making in patients with oropharyngeal squamous cell carcinoma through detection of localized versus advanced cancer stages. Further model refinement and external validation with electronic health records at different institutions are necessary to improve algorithm accuracy and clinical applicability.
Corresponding Author: To contact the corresponding author, Antoine Eskander, M.D., email antoine.eskander@mail.utoronto.ca.
(doi:10.1001/jamaoto.2023.1201)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Sex Differences in Primary Care–Based Chronic Kidney Disease Management
JAMA
EMBARGOED FOR RELEASE: 2:45 P.M. ET, THURSDAY, MAY 16, 2024
Media advisory: The full study is linked to this news release. The study is being released to coincide with presentation at the Society of General Internal Medicine annual meeting.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.8914?guestAccessKey=2d474e45-94e6-4eb2-8419-e90ef782683d&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=051624
About The Study: This study found significant sex differences in primary care–based chronic kidney disease management among patients at a care network affiliated with an academic medical center in the U.S., with females overall receiving worse care than males. Though many differences were of small magnitude, the disparity deserves further examination.
Corresponding Author: To contact the corresponding author, Jorge A. Rodriguez, M.D., email jarodriguez1@partners.org.
(doi:10.1001/jama.2024.8914)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Multiple Onychopapillomas and BAP1 Tumor Predisposition Syndrome
JAMA Dermatology
EMBARGOED FOR RELEASE: 5 P.M. (ET), FRIDAY, MARCH 17, 2024
Media advisory: The full study is linked to this news release. This study is being released to coincide with presentation at the Society for Investigative Dermatology Annual Meeting.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamadermatology/fullarticle/10.1001/jamadermatol.2024.1804?guestAccessKey=f652fe63-9ce2-4011-aa0c-1a820be55a1f&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=051724
About The Study: This study found that BRCA1-associated protein (BAP1) tumor predisposition syndrome was associated with a high rate of nail abnormalities consistent with onychopapillomas (a benign tumor of the nail) in adult carriers of the disease. Findings suggest that this novel cutaneous sign may facilitate detection of the syndrome in family members who are at risk and patients with cancers associated with BAP1 given that multiple onychopapillomas are uncommon in the general population and may be a distinct clue to the presence of a pathogenic germline variant in the BAP1 gene.
Corresponding Authors: To contact the corresponding authors, email Edward W. Cowen, M.D., M.H.Sc. (cowene@mail.nih.gov) and Raffit Hassan, M.D. (hassanr@mail.nih.gov).
(doi:10.1001/jamadermatol.2024.1804)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Federal Trade Commission Actions on Prescription Drugs, 2000-2022
JAMA
EMBARGOED FOR RELEASE: 11 A.M. ET, MONDAY, MAY 20, 2024
Media advisory: The full study and editorial are linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.5737?guestAccessKey=b5df0e55-79b2-4af8-9a64-87a6674156de&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=052024
About The Study: The Federal Trade Commission (FTC) brought about one enforcement action and three merger actions per year against pharmaceutical manufacturers from 2000-2022, pursuing a small fraction of the estimated misconduct and consolidation in the pharmaceutical marketplace. Although the FTC faces substantial legal and practical limitations, important tools remain untested, including a rule defining “unfair methods of competition,” that may allow it to more effectively prevent repetitive patterns of anticompetitive behavior.
Corresponding Author: To contact the corresponding author, Aaron S. Kesselheim, M.D., J.D., M.P.H., email akesselheim@bwh.harvard.edu.
(doi:10.1001/jama.2024.5737)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Pharmacogenomics, Race, and Treatment Outcome in Pediatric Acute Myeloid Leukemia
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Music Therapy in Infancy and Neurodevelopmental Outcomes in Preterm Children
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.10721?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=051624
Trends in Industry-Sponsored Research Payments to Physician Principal Investigators
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.12432?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=051624
Systemic Anticancer Therapy and Overall Survival in Patients With Very Advanced Solid Tumors
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaoncology/fullarticle/10.1001/jamaoncol.2024.1129?guestAccessKey=83379170-74be-4322-8664-95a85cc85fcc&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=051624
Effectiveness of a Web-Based Cognitive Behavioral Self-Help Intervention for Binge Eating Disorder
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, MAY 16, 2024
Media advisory: The full study and commentary are linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.11127?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=051624
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this randomized clinical trial of a web-based self-help intervention for patients with binge eating disorder, the findings confirmed its effectiveness in reducing binge eating episodes and improving various mental health outcomes, highlighting a scalable solution to bridge the treatment gap for this condition.
Corresponding Author: To contact the corresponding author, Luise Pruessner, M.S., email luise.pruessner@psychologie.uni-heidelberg.de.
(doi:10.1001/jamanetworkopen.2024.11127)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Physician and AI Chatbot Responses to Cancer Questions From Social Media
JAMA Oncology
EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, MAY 16, 2024
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaoncology/fullarticle/10.1001/jamaoncol.2024.0836?guestAccessKey=7b38c33b-dcab-4eed-9996-3b74c559a0fa&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=051624
About The Study: The findings of this study suggest that chatbots can generate quality, empathetic, and readable responses to patient questions comparable to physician responses sourced from an online forum. Further research is required to assess the scope, process integration, and patient and physician outcomes of chatbot-facilitated interactions.
Corresponding Author: To contact the corresponding author, Srinivas Raman, M.D., M.A.Sc., email srinivas.raman@rmp.uhn.ca.
(doi:10.1001/jamaoncol.2024.0836)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Pediatric Trauma Center Access, Regional Injury Burden, and Socioeconomic Disadvantage
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Breast Cancer Risk After Bariatric Surgery and Influence of Insulin Levels
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Multidimensional Approach to Exploring Neighborhood Determinants and Symptom Severity Among Individuals With Psychosis
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Sociopolitical Factors and Mental Health Following the Turkey-Syria Earthquake
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Dose-Dependent Association Between Body Mass Index and Mental Health and Changes Over Time
JAMA Psychiatry
EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, MAY 15, 2024
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapsychiatry/fullarticle/10.1001/jamapsychiatry.2024.0921?guestAccessKey=4de6c288-a9ff-4829-87ee-dba5000983cf&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=051524
About The Study: This study revealed a U-shaped association between adolescent body mass index and mental health, which was consistent across sex and grades and became stronger over time. These insights emphasize the need for targeted interventions addressing body image and mental health, and call for further research into underlying mechanisms.
Corresponding Author: To contact the corresponding author, Shanquan Chen, Ph.D., email Shanquan.chen@lshtm.ac.uk.
(10.1001/jamapsychiatry.2024.0921)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Disparities in Patient Portal Engagement Among Patients With Hypertension Treated in Primary Care
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, MAY 15, 2024
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.11649?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=051524
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: This cohort study of patients with hypertension found clear sociodemographic disparities in patient portal engagement among those treated in primary care. Without special efforts to engage patients with portals, interventions that use patient portals to target hypertension may exacerbate disparities.
Corresponding Author: To contact the corresponding author, Rasha Khatib, Ph.D., M.H.S., email rasha.alkhatib@aah.org.
(doi:10.1001/jamanetworkopen.2024.11649)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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An Adaptive Behavioral Intervention for Weight Loss Management
JAMA
EMBARGOED FOR RELEASE: 6:01 P.M. ET, TUESDAY, MAY 14, 2024
Media advisory: The full study and editorial are linked to this news release. The study is being released to coincide with the European Congress on Obesity.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.0821?guestAccessKey=6d6633c0-8d44-48b2-a3eb-e97abf6c9a3a&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=051424
About The Study: A wireless feedback system (Wi-Fi activity tracker and scale with smartphone app to provide daily feedback) was not noninferior to the same system with added coaching. Continued efforts are needed to identify strategies for weight loss management and to accurately select interventions for different individuals to achieve weight loss goals.
Quote from corresponding author Bonnie Spring, Ph.D.:
“With U.S. obesity prevalence projected to reach 49% by 2030, limited obesity treatment resources need to be spread across more of the population. One promising approach is stepped care that begins with low cost, self-monitoring technology alone, then intensifies treatment for those who show insufficient response.
“It has been unknown whether first line technology treatment alone could produce clinically acceptable weight loss. In an adaptive randomized noninferiority trial, people who initially only received technology without coach support were less likely to achieve meaningful weight loss (5% of body weight), compared to those who had a human coach at the start.
“Currently, a human coach remains needed from the outset of obesity treatment because digital technology alone doesn’t produce clinically acceptable weight loss for most people.”
Contact information for Dr. Spring: email bspring@northwestern.edu.
(doi:10.1001/jama.2024.0821)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Text Messages With Financial Incentives for Men With Obesity
JAMA
EMBARGOED FOR RELEASE: 6:01 P.M. ET, TUESDAY, MAY 14, 2024
Media advisory: The full study and editorial are linked to this news release. The study is being presented at the European Congress on Obesity.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.7064?guestAccessKey=e5e4f13d-f93c-4d64-b9fb-c579e4b06a33&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=051424
About The Study: Among men with obesity, an intervention with text messaging with financial incentive significantly improved weight loss compared with a control group, whereas text messaging alone was not significantly better than the control condition. These findings support text messaging combined with financial incentives to attain weight loss in men with obesity.
Quote from corresponding author Prof. Pat Hoddinott, M.B., B.S., Ph.D.:
“Losing weight can make people feel better, reduce their risk of many health problems such as diabetes, and helps the health service with their aim to keep men well. However, we know men often don’t like to go to traditional weight loss groups.
“This was a very carefully planned study, created for men by men. We worked closely with various men’s health groups and charities, including Men’s Health Forum in the UK and Ireland, with more than 1000 men living with obesity informing the design of the incentive structure.
“The research showed that offering cash incentives was a popular and effective way of helping men to lose weight. This initiative would be a low-cost solution for the health service to offer to men, requiring only four short weight appointments, and with money paid out only at the end to those who lose over 5% of their starting weight.”
Contact information for Prof. Hoddinott:
Press officer: Sarah Manning, sarah.manning@stir.ac.uk; 01786 466436 / 07341 052 750.
(doi:10.1001/jama.2024.7064)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Cardiovascular Burden of the V142I Transthyretin Variant
JAMA
EMBARGOED FOR RELEASE: 3:30 A.M. ET, SUNDAY, MAY 12, 2024
Media advisory: The full study and editorials are linked to this news release. The study is being released to coincide with presentation at the European Society of Cardiology-Heart Failure Congress.
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About The Study: Among self-reported Black individuals, male and female V142I carriers faced similar and substantial risk for heart failure hospitalization, predominantly with reduced ejection fraction, and death, with steep age-dependent penetrance. Delineating the individual contributions of, and complex interplay among, the V142I variant, ancestry, the social construct of race, and biological or social determinants of health to cardiovascular disease merits further investigation.
Corresponding Author: To contact the corresponding author, Scott D. Solomon, M.D., email ssolomon@rics.bwh.harvard.edu.
(doi:10.1001/jama.2024.4467)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Cord Blood Proteomic Profiles, Birth Weight, and Early Life Growth Trajectories
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Public Attitudes, Interests, and Concerns Regarding Polygenic Embryo Screening
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Eye-Tracking Biomarkers and Autism Diagnosis in Primary Care
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Exploring Anabolic Androgenic Steroid Use Among Cisgender Gay, Bisexual, and Queer Men
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Mortality in Patients Hospitalized for COVID-19 vs Influenza in Fall-Winter 2023-2024
JAMA
EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, MAY 15, 2024
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.7395?guestAccessKey=93a190ab-5a8a-4dcb-b76f-129dd3bafa63&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=051524
About The Study: This study found that in fall-winter 2023-2024, the risk of death in patients hospitalized for COVID-19 was greater than the risk of death in patients hospitalized for seasonal influenza.
Corresponding Author: To contact the corresponding author, Ziyad Al-Aly, M.D., email ziyad.alaly@va.gov.
(doi:10.1001/jama.2024.7395)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Patent Portfolios Protecting 10 Top-Selling Prescription Drugs
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Anti-Asian Hate and the Health of Older Asian Individuals
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Effect of Low-Dose Iron Supplementation on Early Development in Breastfed Infants
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US Immigration Policy Stressors and Latinx Youth Mental Health
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Telehealth Expansion and Medicare Beneficiaries’ Care Quality and Access
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. ET, MONDAY, MAY 13, 2024
Media advisory: The full study is linked to this news release.
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this cohort study of Medicare beneficiaries across all 3,436 hospital service areas (HSAs), high levels of telehealth use were associated with more clinician encounters, more ambulatory care–sensitive hospitalizations, and higher total health care costs. COVID-19 cases were still high during the period of study, which suggests that these findings partially reflect a higher capacity for providing health services in HSAs with higher telehealth intensity than other HSAs.
Corresponding Author: To contact the corresponding author, Sara Parker-Lue, Ph.D., email sparkerlue@air.org.
(doi:10.1001/jamanetworkopen.2024.11006)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Mail-Order Pharmacy Dispensing of Mifepristone for Medication Abortion After In-Person Screening
JAMA Internal Medicine
EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, MAY 13, 2024
Media advisory: The full study and Viewpoint are linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/10.1001/jamainternmed.2024.1476?guestAccessKey=b1e95fa9-c670-485e-bb0e-864019276c9f&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=051324
About The Study: The findings of this cohort study indicate that mail-order pharmacy dispensing of mifepristone for medication abortion was effective, acceptable to patients, and feasible, with a low prevalence of serious adverse events. This care model should be expanded to improve access to medication abortion services.
Corresponding Author: To contact the corresponding author, Daniel Grossman, M.D., email daniel.grossman@ucsf.edu.
(doi:10.1001/jamainternmed.2024.1476)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Causal Inference About the Effects of Interventions From Observational Studies in Medical Journals
JAMA
EMBARGOED FOR RELEASE: 11:30 A.M. ET, THURSDAY, MAY 9, 2024
Media advisory: The full study and editor’s note are linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.7741?guestAccessKey=4a0c808a-a6e6-47b1-b44f-336494081397&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=050924
About The Study: Adoption of the proposed framework to identify when causal interpretation is appropriate in observational studies promises to facilitate better communication between authors, reviewers, editors, and readers. Practical implementation will require cooperation between editors, authors, and reviewers to operationalize the framework and evaluate its effect on the reporting of empirical research.
Corresponding Author: To contact the corresponding author, Issa J. Dahabreh, M.D., Sc.D., email idahabreh@hsph.harvard.edu.
(doi:10.1001/jama.2024.7741)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Share of Adult Suicides After Recent Jail Release
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