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Trends in Ethnic Disparities in Stroke Care and Long-Term Outcomes
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COVID-19 Vaccine Hesitancy Among Black Women in the US
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, JANUARY 9, 2025
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.53511?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=010925
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The results of this study suggest that addressing COVID-19 vaccine hesitancy among Black women requires a multifaceted approach that acknowledges historical traumas, provides clear and transparent safety information, and avoids coercive vaccine promotion strategies. These findings emphasize the need for health care practitioners and public health officials to prioritize trust-building, engage community leaders, and tailor interventions to address the unique concerns of Black women to improve vaccine confidence and uptake.
Corresponding Author: To contact the corresponding author, Brittany C. Slatton, PhD, email brittany.slatton@tsu.edu.
(doi:10.1001/jamanetworkopen.2024.53511)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.
Weight Changes and Heart Failure Risk After Breast Cancer Development
JAMA Oncology
EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, JANUARY 9, 2025
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaoncology/fullarticle/10.1001/jamaoncol.2024.5803?guestAccessKey=0c8f348a-b354-4a78-8eb1-29ba9bc50370&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=010925
About The Study: In this nationwide cohort study in the Republic of Korea, postdiagnosis weight gain was associated with an increased risk of heart failure after breast cancer development, with risk escalating alongside greater weight gain. The findings underscore the importance of effective weight intervention in the oncological care of patients with breast cancer, particularly within the first few years after diagnosis, to protect cardiovascular health.
Corresponding Author: To contact the corresponding author, Dong Wook Shin, MD, DrPH, MBA, email dwshin@skku.edu.
(doi:10.1001/jamaoncol.2024.5803)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Changes in Patient Care Experience After Private Equity Acquisition of US Hospitals
JAMA
EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, JANUARY 9, 2025
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.23450?guestAccessKey=13ff133a-e843-4e58-814e-6b3c16a7b66c&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=010925
About The Study: This study found that patient care experience worsened after private equity acquisition of hospitals. These findings raise concern about the implications of private equity acquisitions on patient care experience at U.S. hospitals.
Corresponding Author: To contact the corresponding author, Rishi K. Wadhera, MD, MPP, MPhil, email rwadhera@bidmc.harvard.edu.
(doi:10.1001/jama.2024.23450)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Physician Payment Incentives and Active Surveillance in Low-Risk Prostate Cancer
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Irritability and Social Media Use in US Adults
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Uptake of Maternal RSV Vaccination and Infant Nirsevimab Among Infants Born October 2023 to March 2024
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Development and Validation of a Tool to Predict Onset of Mild Cognitive Impairment and Alzheimer Dementia
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, JANUARY 8, 2025
Media advisory: The full study is linked to this news release.
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this prognostic study, with the use of a statistical modeling approach, the Florey Dementia Index was developed and validated to predict the onset age of mild cognitive impairment and Alzheimer dementia. This tool may be useful in organizing health care for older adults with cognitive decline or dementia and in the future may help prioritize patients for the use of disease-modifying monoclonal antibody drugs.
Corresponding Authors: To contact the corresponding authors, email Yijun Pan, PhD (yijun.pan@unimelb.edu.au) and Liang Jin, PhD (liang.jin@unimelb.edu.au).
(doi:10.1001/jamanetworkopen.2024.53756)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Cost-Effectiveness of a Polypill for Cardiovascular Disease Prevention in an Underserved Population
JAMA Cardiology
EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, JANUARY 8, 2025
Media advisory: The full study and editor’s note are linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamacardiology/fullarticle/10.1001/jamacardio.2024.4812?guestAccessKey=99044e91-31bb-43a6-bf32-d1e42e9b434c&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=010825
About The Study: The results of this economic evaluation suggest that cardiovascular polypill treatment (single pill containing a statin and 3 half-standard dose antihypertensives) could be a high value intervention for a low-income, majority Black population with limited access to health care services. It could additionally reduce health disparities.
Corresponding Author: To contact the corresponding author, Ciaran N. Kohli-Lynch, PhD, email ciaran.kohli-lynch@northwestern.edu.
(doi:10.1001/jamacardio.2024.4812)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflicts of interest and financial disclosures, and funding and support.
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Prescriptions and Reimbursement of Glucagon Products for Severe Hypoglycemia in Medicaid
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SPRINT Treatment Among Adults With Chronic Kidney Disease From 2 Large Health Care Systems
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National Telehealth Contingency Staffing Program and Primary Care Quality in the VHA
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Macronutrients in Human Milk Exposed to Antidepressant and Anti-Inflammatory Medications
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. ET, TUESDAY, JANUARY 7, 2025
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.53332?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=010725
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this cross-sectional study, some maternal medications were associated with lower levels of protein and fat in milk, which could impose health risks for breastfed infants. Other factors that could influence macronutrient levels need to be clarified before the clinical implications of these findings can be confirmed.
Corresponding Author: To contact the corresponding author, Essi Whaites Heinonen, MD, PhD, email essi.heinonen@ki.se.
(doi:10.1001/jamanetworkopen.2024.53332)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Severe Maternal Morbidity Among Pregnant People With Opioid Use Disorder Enrolled in Medicaid
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. ET, TUESDAY, JANUARY 7, 2025
Media advisory: The full study is linked to this news release.
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: This cross-sectional study of pregnant people enrolled in Medicaid found that the rate of opioid use disorder among this group was more than twice as high as previous estimates. Pregnant people with opioid use disorder face a disproportionately high risk of severe maternal morbidity, particularly those who enroll in Medicaid later in pregnancy. Targeted interventions that facilitate early Medicaid enrollment and coverage continuity may be needed to reduce the burden of adverse outcomes in this group.
Corresponding Author: To contact the corresponding author, Samantha G. Auty, PhD, email sgauty@bu.edu.
(doi:10.1001/jamanetworkopen.2024.53303)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Predatory Journals – What Can We Do to Protect Their Prey?
JAMA
EMBARGOED FOR RELEASE: 5 P.M. ET, MONDAY, JANUARY 6, 2025
Media advisory: The full editorial is linked to this news release.
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Editorial: Predatory journals pose significant risks to authors, institutions, and the scientific community by disseminating unvetted and potentially fraudulent information.
Corresponding Author: To contact the corresponding author, Christina C. Wee, MD, MPH:
https://icmje.org/about-icmje/contact-icmje/
(doi:10.1001/jama.2024.27514)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Oral Glucose-Lowering Agents vs Insulin for Gestational Diabetes
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Reassessing the Inclusion of Race in Prenatal Screening for Open Neural Tube Defects
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Gender-Affirming Medications Among Transgender Adolescents in the US, 2018-2022
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Role of Social Determinants of Health in COVID-19 Recovery
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JAMA Health Forum—Paving the Way for the Future of Health Policy Science and Scholarship
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About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
Burden of Infections in Early Life and Risk of Infections and Systemic Antibiotics Use in Childhood
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. ET, MONDAY, JANUARY 6, 2025
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.53284?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=010625
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: This longitudinal cohort study suggests that early-life infection burden may continue throughout childhood and is associated with later antibiotic treatments independent of social and environmental risk factors. These findings are important for prognosis and follow-up of children experiencing a high burden of common infections in early life.
Corresponding Author: To contact the corresponding author, Nicklas Brustad, MD, PhD, email nicklas.brustad@dbac.dk.
(doi:10.1001/jamanetworkopen.2024.53284)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Trends in Treatment Need and Receipt for Substance Use Disorders in the US
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. ET, MONDAY, JANUARY 6, 2025
Media advisory: The full study is linked to this news release.
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: This cross-sectional study’s analysis underscores a public health crisis of substance use disorder. The prevalence of substance use disorder surged during the COVID-19 pandemic, yet the receipt of treatment declined initially as health care services were disrupted. Treatment rates began to recover in 2022, likely due to reopened treatment programs and increased telehealth use.
Corresponding Author: To contact the corresponding author, Milap C. Nahata, PharmD, MS, email nahata.1@osu.edu.
(doi:10.1001/jamanetworkopen.2024.53317)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Fluoride Exposure and Children’s IQ Scores
JAMA Pediatrics
EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, JANUARY 6, 2025
Media advisory: The full study and editorials are linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapediatrics/fullarticle/10.1001/jamapediatrics.2024.5542?guestAccessKey=f61d2921-6a2b-436a-8710-c9623f148bdf&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=010625
About The Study: This systematic review and meta-analysis found inverse associations and a dose-response association between fluoride measurements in urine and drinking water and children’s IQ across the large multi-country epidemiological literature. There were limited data and uncertainty in the dose-response association between fluoride exposure and children’s IQ when fluoride exposure was estimated by drinking water alone at concentrations less than 1.5 mg/L. These findings may inform future comprehensive public health risk-benefit assessments of fluoride exposures.
Corresponding Author: To contact the corresponding author, Kyla W. Taylor, PhD, email kyla.taylor@nih.gov.
(doi:10.1001/jamapediatrics.2024.5542)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Trends in Screening for Social Risk in Physician Practices
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, JANUARY 3, 2025
Media advisory: The full study and commentary are linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.53117?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=010325
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this survey-based cross-sectional study of U.S. physician practices, social risk screening increased substantially from 2017 to 2022, although still less than one-third of practices systematically screened for a set of 5 common social risks (food, housing, utilities, interpersonal violence, and transportation). What remains to be seen is whether practices use these data to help improve patient health by adjusting health care or referring patients for assistance with social needs. As policies and incentives increasingly emphasize social risk screening, it will be important to assess the association of screening and referrals with patient outcomes.
Corresponding Author: To contact the corresponding author, Amanda L. Brewster, PhD, email amanda.brewster@berkeley.edu.
(doi:10.1001/jamanetworkopen.2024.53117)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Risk Model–Guided Clinical Decision Support for Suicide Screening
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Social Risks and Nonadherence to Recommended Cancer Screening Among US Adults
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Validating a Case Definition for Transgender Adults Using Administrative Data
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Exposure to School Racial Segregation and Late-Life Cognitive Outcomes
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, JANUARY 3, 2025
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.52713?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=010325
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: This cross-sectional study of Black and white older individuals found that childhood exposure to school segregation was associated with late-life cognition among the Black population. Given the increasing amount of school segregation in the U.S., educational policies aimed at reducing segregation are needed to address health inequities. Clinicians may leverage patients’ early-life educational circumstances to promote screening, prevention, and management of cognitive disorders.
Corresponding Author: To contact the corresponding author, Xi Chen, PhD, email xi.chen@yale.edu.
(doi:10.1001/jamanetworkopen.2024.52713)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Mental Disorders Among Offspring Prenatally Exposed to Systemic Glucocorticoids
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, JANUARY 3, 2025
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.53245?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=010325
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this cohort study, prenatal exposure to glucocorticoids was associated with higher risk of some mental disorders. These data support continued caution in the use of glucocorticoids in pregnant people.
Corresponding Author: To contact the corresponding author, Kristina Laugesen, PhD, email kristina.laugesen@clin.au.dk.
(doi:10.1001/jamanetworkopen.2024.53245)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Prevalence of Dementia Among Adults With Autism Spectrum Disorder
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Geographic Distribution of US Ophthalmic Surgical Subspecialists
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Residential Differences and Depression Among Older Adults With Dual Sensory Loss
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Cardiovascular Disease and Breast Cancer Stage at Diagnosis
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, JANUARY 2, 2025
Media advisory: The full study is linked to this news release.
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: This case-control study found that individuals with more advanced breast cancer at diagnosis were more likely to have prevalent cardiovascular disease. This finding may be specific to hormone receptor–positive and ERBB2-negative (formerly HER2) disease. Future studies are needed to confirm these findings and investigate interventions to improve patient outcomes, including personalized cancer screening.
Corresponding Author: To contact the corresponding author, Kevin T. Nead, MD, MPhil, email ktnead@mdanderson.org.
(doi:10.1001/jamanetworkopen.2024.52890)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Knowledge and Worry Following Review of Standard vs Patient-Centered Pathology Reports
JAMA
EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, JANUARY 2, 2025
Media advisory: The full study is linked to this news release.
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About The Study: Most study participants could not extract basic information—including whether they have cancer—from standard prostate cancer pathology reports but were able to understand this diagnostic information from the patient-centered pathology reports (PCPRs). Also, they discriminated between risk levels (i.e., lower levels of perceived worry in the low-risk condition) with PCPRs compared with standard reports. Hospital systems should consider including PCPRs with standard pathology reports to improve patient understanding.
Corresponding Author: To contact the corresponding author, Cathryn J. Lapedis, MD, MPH, MS, email cathrynb@med.umich.edu.
(doi:10.1001/jama.2024.25461)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Pain Coping Skills Training for Patients Receiving Hemodialysis
JAMA Internal Medicine
EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, DECEMBER 30, 2024
Media advisory: The full study is linked to this news release.
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About The Study: In this randomized clinical trial of patients undergoing maintenance hemodialysis, pain coping skills training had benefits on pain interference and other pain-associated outcomes. While the effect on the overall cohort was of modest magnitude, the intervention resulted in a clinically meaningful improvement in pain interference for a substantial proportion of participants.
Corresponding Author: To contact the corresponding author, Laura M. Dember, MD, email ldember@pennmedicine.upenn.edu.
(doi:10.1001/jamainternmed.2024.7140)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Trends of Violence in Movies During the Past Half Century
JAMA Pediatrics
EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, DECEMBER 30, 2024
Media advisory: The full study is linked to this news release.
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About The Study: The results of this study suggest that speech about committing murder in movies is increasing over time, even in non-crime movies, regardless of character gender. These results are consistent with previous findings that highlighted increasing trends of violence using smaller datasets.
Corresponding Author: To contact the corresponding author, Brad J. Bushman, PhD, email bushman.20@osu.edu.
(doi:10.1001/jamapediatrics.2024.5741)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Major Depressive Disorder and Driving Behavior Among Older Adults
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. ET, MONDAY, DECEMBER 30, 2024
Media advisory: The full study is linked to this news release.
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this longitudinal cohort study of older drivers, adults with major depressive disorder demonstrated distinct and riskier driving behaviors than those in the control group without depression, with higher rates of hard braking, cornering, and unpredictability in driving patterns over time. Routine depression screening and tailored interventions are essential for enhancing driving safety and maintaining independence among older adults with major depressive disorder.
Corresponding Author: To contact the corresponding author, Ganesh M. Babulal, PhD, OTD, email babulalg@wustl.edu.
(doi:10.1001/jamanetworkopen.2024.52038)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Breast Cancer Susceptibility Gene Sequence Variations and Development of Contralateral Breast Cancer
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Physician Engagement in Addressing Health-Related Social Needs and Burnout
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Neuroanatomical Variability and Substance Use Initiation in Late Childhood and Early Adolescence
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Antibody Response to RSV Vaccination in Immunocompromised Persons
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Adherence to FDA Guidance on Pulse Oximetry Testing Among Diverse Individuals
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Alcohol Use Disorder Polygenic Score Compared With Family History and ADH1B
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Flavored E-Cigarette Sales Restrictions and Young Adult Tobacco Use
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About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
Symptoms Prior to Diagnosis of Multiple Sclerosis in Individuals Younger Than 18 Years
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Household Food Allergen Exclusion Practices and Food Allergy-Related Psychosocial Functioning
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Estimated Vaccine Effectiveness for Pediatric Patients With Severe Influenza
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, DECEMBER 27, 2024
Media advisory: The full study is linked to this news release.
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The findings from this case-control study suggest that children should receive influenza vaccination to protect against all levels of severe influenza illness.
Corresponding Authors: To contact the corresponding authors, email Kelsey M. Sumner, PhD, MSPH (rhq3@cdc.gov) and Samantha M. Olson, MPH (ylz8@cdc.gov).
(doi:10.1001/jamanetworkopen.2024.52512)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Changes to the US Preventive Services Task Force Screening Guidelines and Incidence of Breast Cancer
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, DECEMBER 27, 2024
Media advisory: The full study is linked to this news release.
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this cohort study, in situ breast cancer decreased since 2009, consistent with decreasing use of screening mammography since the 2009 U.S. Preventive Services Task Force guideline changes, but this decrease did not appear to have translated to more advanced breast cancer stages at diagnosis or decreases in the proportion of cases treated with partial mastectomy. Further research is needed to understand the long-standing increase in localized invasive breast cancer and the decrease in regional invasive breast cancer observed during the past 20 years in the context of decreased breast cancer screening.
Corresponding Author: To contact the corresponding author, Carina Zhang-Petersen, MD, email carina.zhang-petersen@uvmhealth.org.
(doi:10.1001/jamanetworkopen.2024.52688)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Persistent Short Sleep Duration From Pregnancy to 2 to 7 Years After Delivery and Metabolic Health
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, DECEMBER 26, 2024
Media advisory: The full study is linked to this news release.
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this study, short sleep duration that persisted from pregnancy to 2 to 7 years after delivery was associated with a greater risk for adverse cardiometabolic outcomes. Future studies should explore whether sleep-targeted interventions during and after pregnancy are associated with improved cardiometabolic health outcomes, particularly among populations at increased risk.
Corresponding Author: To contact the corresponding author, Minjee Kim, MD, email minjee.kim@northwestern.edu.
(doi:10.1001/jamanetworkopen.2024.52204)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Kidney Function Decline After COVID-19 Infection
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, DECEMBER 26, 2024
Media advisory: The full study is linked to this news release.
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: This cohort study found an association between COVID-19 and accelerated decline in kidney function, particularly after hospitalization, compared with pneumonia. People who were hospitalized for COVID-19 should receive closer monitoring of kidney function to ensure early diagnosis and optimized management of chronic kidney disease to effectively prevent complications and further decline.
Corresponding Author: To contact the corresponding author, Viyaasan Mahalingasivam, MPhil, email viyaasan.mahalingasivam@nhs.net.
(doi:10.1001/jamanetworkopen.2024.50014)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Aerobic Exercise and Weight Loss in Adults
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, DECEMBER 26, 2024
Media advisory: The full study is linked to this news release.
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this meta-analysis of randomized clinical trials, engaging in 30 minutes of aerobic exercise per week was associated with modest reductions in body weight, waist circumference, and body fat measures among adults with overweight or obesity. However, aerobic training exceeding 150 minutes per week at moderate intensity or greater may be needed to achieve clinically important reductions.
Corresponding Author: To contact the corresponding author, Ahmad Jayedi, PhD, email a.jayedi@imperial.ac.uk.
(doi:10.1001/jamanetworkopen.2024.52185)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Discordant Information on Blinding in Trial Registries and Published Research
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Maternal and Infant Health Outcomes in US-Born and Non–US-Born Black Pregnant People in the US
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Suicide Risk Among Veterans Who Receive Evidence-Based Therapy for PTSD
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Deep Learning Model for Predicting Immunotherapy Response in Advanced Non−Small Cell Lung Cancer
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Availability of Dental Benefits Within Medicare Advantage Plans by Enrollment and County
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Dental Clinic Deserts in the US: Spatial Accessibility Analysis
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Depression and Suicide Risk Screening in the Veterans Health Administration
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Variation in Emergency Department Physician Admitting Practices and Subsequent Mortality
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Association of State Cannabis Legalization With Cannabis Use Disorder and Cannabis Poisoning
JAMA Psychiatry
EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, DECEMBER 23, 2024
Media advisory: The full study is linked to this news release.
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About The Study: In this longitudinal cohort study, medical cannabis laws were associated with increased cannabis use disorder and cannabis poisoning diagnoses, and recreational cannabis laws were associated with increased cannabis poisoning in adults ages 18 to 64 with employer-sponsored health insurance. Communities with increased access to cannabis may experience increased health care use and costs due to increases in cannabis poisoning and cannabis use disorder, and new clinical and policy interventions are needed to curb these rising diagnoses.
Corresponding Author: To contact the corresponding author, Jayani Jayawardhana, PhD, email jayani.jayawardhana@uky.edu.
(10.1001/jamapsychiatry.2024.4145)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Firearm and Motor Vehicle Pediatric Deaths— Intersections of Age, Sex, Race, and Ethnicity
JAMA Pediatrics
EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, DECEMBER 23, 2024
Media advisory: The full study is linked to this news release.
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About The Study: In this cross-sectional study, U.S. youths ages 0 to 19 years experienced important disparities in firearm and motor vehicle crash fatality rates and increases over time when considering the intersectionality by age group, sex, race, and ethnicity. These findings suggest that a multipronged strategy focused on individual, community, and policy level approaches for specific high-risk groups for each injury mechanism is necessary to address these leading causes of death in U.S. youths.
Corresponding Author: To contact the corresponding author, Lois K. Lee, MD, MPH, email lois.lee@childrens.harvard.edu.
(doi:10.1001/jamapediatrics.2024.5089)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Gestational Hypertension, Preeclampsia, and Eclampsia and Future Neurological Disorders
JAMA Neurology
EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, DECEMBER 23, 2024
Media advisory: The full study is linked to this news release.
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About The Study: In this study, gestational hypertension, preeclampsia, and eclampsia were associated with an increased risk of new-onset migraine, headache, epilepsy, sleep disorder, or mental fatigue within months to years after giving birth. Guidelines recommend follow-up after delivery for women with gestational hypertension and preeclampsia for their increased risk of cardiovascular disease. At these visits, caregivers should also pay attention to persisting or new-onset of neurological symptoms, since this group of women appears to be vulnerable to developing or experiencing neurological disorders.
Corresponding Author: To contact the corresponding author, Therese Friis, MD, email therese.friis@uu.se.
(doi:10.1001/jamaneurol.2024.4426)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Universal Health Checkups and Risk of Incident Diabetes and Hypertension
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Childhood Exposure to Interparental Physical Violence and Adult Cardiovascular Disease
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Trends in Opioid Use Disorder in the Veterans Health Administration
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Socioeconomic Status, Diet, and Behavioral Factors and Cardiometabolic Diseases and Mortality
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Cat and Dog Exposures to Cocaine or Methamphetamine
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Trends in Buprenorphine Dispensing Among Adolescents and Young Adults in the US
JAMA
EMBARGOED FOR RELEASE: 11 A.M. ET, MONDAY, DECEMBER 23, 2024
Media advisory: The full study is linked to this news release.
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About The Study: Between 2020 and 2023, buprenorphine dispensing increased among adolescents but decreased among young adults. The increases likely reflect successful outreach to pediatricians, enhanced prescribing through telehealth, and elimination of waiver requirements; these changes might differentially affect young adults, who might be less likely to access health care.
Corresponding Author: To contact the corresponding author, Andrew Terranella, MD, MPH, email aqt1@cdc.gov.
(doi:10.1001/jama.2024.24121)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Disparities and Gaps in Breast Cancer Screening for Women Ages 40 to 49
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, DECEMBER 20, 2024
Media advisory: The full study is linked to this news release.
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The findings of this cross-sectional study underscore significant disparities and gaps in biennial mammography screening for women ages 40 to 49. Two-fifths of women in this age group did not receive biennial screening. Lower biennial screening rates were observed among racial and ethnic minority populations, sexual minority populations, rural residents, and socioeconomically disadvantaged populations. To optimize early breast cancer detection, ensuring equitable adherence to U.S. Preventive Services Task Force recommendations is crucial.
Corresponding Author: To contact the corresponding author, Minghui Li, PhD, email mli54@uthsc.edu.
(doi:10.1001/jamanetworkopen.2024.51827)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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US Tobacco 21 Policies and Potential Mortality Reductions by State
JAMA Health Forum
EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, DECEMBER 20, 2024
Media advisory: The full study is linked to this news release.
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About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
About The Study: This study found that early adoption and implementation of Tobacco 21 (T21) policies (minimum age of 21 for legal access to tobacco products) maximizes potential premature mortality reductions. However, the strength of T21 policies and enforcement varies widely across states. Enforcement of the federal T21 law is critical in the 8 states without state-level T21 cigarette policies of their own.
Corresponding Author: To contact the corresponding author, Jamie Tam, PhD, email jamie.tam@yale.edu.
(doi:10.1001/jamahealthforum.2024.4445)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Incidence and Risk of Cardiovascular Outcomes in Patients With Anorexia Nervosa
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Cold-Related Deaths in the US
JAMA
EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, DECEMBER 19, 2024
Media advisory: The full study is linked to this news release.
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About The Study: Cold-related mortality rates more than doubled in the U.S. between 1999 and 2022. Prior research suggests that cold temperatures account for most temperature-related mortality. This study identified an increase in such deaths over the past 6 years. The underlying drivers of this trend warrant further research and may include more frequent extreme winter weather events and/or the rising burden of risk factors for cold-related mortality such as homelessness, social isolation, and substance use.
Corresponding Author: To contact the corresponding author, Rishi K. Wadhera, MD, MPP, MPhil, email rwadhera@bidmc.harvard.edu.
(doi:10.1001/jama.2024.25194)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Optimal Stopping Ages for Colorectal Cancer Screening
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Symptoms, Quality of Life, and Executive Function in Children Who Snore
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Physical Activity During Pregnancy and Preterm Birth Among Women With Gestational Diabetes
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, DECEMBER 19, 2024
Media advisory: The full study is linked to this news release.
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this prospective cohort study, moderate-to-vigorous intensity physical activity (MVPA) during pregnancy was associated with a lower risk of preterm birth among women with gestational diabetes. Concentrated physical activity was associated with similar benefits in reducing preterm birth risk as regular physical activity. These findings provide key evidence for the health benefits of MVPA during pregnancy and lay the foundation for establishing physical activity guidelines for pregnant women with gestational diabetes.
Corresponding Author: To contact the corresponding author, Ju-Sheng Zheng, PhD, email zhengjusheng@westlake.edu.cn.
(doi:10.1001/jamanetworkopen.2024.51799)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Racial and Ethnic Differences in Outcomes of Neonates Born at Less Than 30 Weeks’ Gestation
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, DECEMBER 19, 2024
Media advisory: The full study is linked to this news release.
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this cohort study, there were no differences in mortality rates between Black and white newborns, but Black newborns had higher rates of necrotizing enterocolitis and late-onset sepsis. Continued quality improvement and addressing social determinants of health are critical for promoting health equity in hospital outcomes and beyond.
Corresponding Author: To contact the corresponding author, Nansi S. Boghossian, PhD, email nboghoss@mailbox.sc.edu.
(doi:10.1001/jamanetworkopen.2024.51707)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Brief Outpatient Rehabilitation Program for Post–COVID-19 Condition
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, DECEMBER 19, 2024
Media advisory: The full study and commentary are linked to this news release.
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this randomized clinical trial that compared a brief outpatient rehabilitation program with a cognitive and behavioral approach with usual care in 314 patients with post–COVID-19 condition, self-reported physical function improved statistically and clinically significantly in the intervention group after 2 to 8 outpatient encounters. The effect was sustained over time and adverse effects were negligible. This trial adds to the evidence supporting such interventions in routine clinical care. Future research should investigate which elements of this approach are the most effective and identify subgroups for which the current treatment is most relevant.
Corresponding Author: To contact the corresponding author, Tom Farmen Nerli, MD, email tomfar@siv.no.
(doi:10.1001/jamanetworkopen.2024.50744)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Self-Guided vs Clinician-Guided Online Cognitive Behavioral Therapy for Atopic Dermatitis
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Potential Policy Targets to Reduce Vaping Among Youths
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Frontal White Matter Changes and Craving Recovery in Inpatients With Heroin Use Disorder
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Racial and Ethnic Disparities in Child Abuse Identification and Inpatient Treatment
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, DECEMBER 18, 2024
Media advisory: The full study and commentary are linked to this news release.
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: This study found that Black children and adolescents were suspected to have experienced child abuse at higher rates than children and adolescents of other racial and ethnic backgrounds. More research is necessary to understand the origins of these disparities to reduce them in child abuse identification.
Corresponding Author: To contact the corresponding author, Norah E. Liang, MD, email nliang@stanford.edu.
(doi:10.1001/jamanetworkopen.2024.51588)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Trajectory of Cardiovascular Health Across Childhood and Adolescence
JAMA Cardiology
EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, DECEMBER 18, 2024
Media advisory: The full study and editorial are linked to this news release.
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About The Study: In this cohort of 1,500 children, across demographic subgroups, the trajectory of cardiovascular health (CVH) scores began to decline at approximately age 10, associated with health behaviors rather than health factors. Statistically significant (albeit small) differences in CVH trajectory parameters by sociodemographic characteristics were also identified. This study provides insight into the trajectory of CVH early in life, which may contribute to CVH disparities in adulthood, and identified modifiable health behaviors for focused prevention efforts to optimize CVH in early life.
Corresponding Author: To contact the corresponding author, Izzuddin M. Aris, PhD, email izzuddin_aris@hphci.harvard.edu.
(doi:10.1001/jamacardio.2024.4022)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflicts of interest and financial disclosures, and funding and support.
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Physical Activity Engagement After Tai Ji Quan Intervention Among Older Adults With Mild Cognitive Impairment or Memory Concerns
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Biased Language in Simulated Handoffs and Clinician Recall and Attitudes
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Cannabis Use and Trajectories of Depression and Stress Across the Prenatal Period
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Daily Physical Activity, Sports Participation, and Executive Function in Children
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. ET, TUESDAY, DECEMBER 17, 2024
Media advisory: The full study and commentary are linked to this news release.
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this cohort study of Dutch children, early-life moderate to vigorous physical activity was not associated with executive function in middle childhood. Children participating in team sports at ages 10 to 11 consistently exhibited superior executive function compared with participants in individual sports.
Corresponding Author: To contact the corresponding author, Lu Yang, MSc, email l.yang@umcg.nl.
(doi:10.1001/jamanetworkopen.2024.49879)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Unionization Efforts by Physicians Between 2000 and 2024
JAMA
EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, DECEMBER 18, 2024
Media advisory: The full study is linked to this news release.
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About The Study: Compared with 2000-2022, the number of union petitions with physicians in the bargaining units filed and certified increased in 2023 through May 2024. Organizing efforts were motivated by concerns about working conditions, physicians’ autonomy, and voice in management, and the quality of patient care.
Corresponding Author: To contact the corresponding author, Kevin Schulman, MD, email kevin.schulman@stanford.edu.
(doi:10.1001/jama.2024.23721)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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2024 Update of the RECOVER-Adult Long COVID Research Index
JAMA
EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, DECEMBER 18, 2024
Media advisory: The full study is linked to this news release.
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About The Study: The 2024 long COVID research index for adults builds on the 2023 index with additional data and symptoms to help researchers classify symptomatic long COVID and its symptom subtypes. Continued future refinement of the index will be needed as the understanding of long COVID evolves.
Corresponding Author: To contact the corresponding author, Leora I. Horwitz, MD, MHS, email leora.horwitz@nyulangone.org.
(doi:10.1001/jama.2024.24184)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Obesity and Glucagon-Like Peptide-1 Receptor Agonists
JAMA
EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, DECEMBER 18, 2024
Media advisory: The full article is linked to this news release.
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About The Article: In this Viewpoint, authors from the World Health Organization discuss factors associated with the prevalence of obesity worldwide and whether the novel glucagon-like peptide-1 receptor agonists (GLP-1 RAs) can help unlock a health systems response to the obesity pandemic.
Corresponding Author: To contact the corresponding author, Francesca Celletti, MD, PhD, email cellettif@who.int.
(doi:10.1001/jama.2024.25872)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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FDA Approval of Pediatric AI and Machine Learning–Enabled Medical Devices
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Lithium Use During Pregnancy in 14 Countries
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Coronary Microvascular Dysfunction Years After Cessation of Anabolic Androgenic Steroid Use
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Quality of Hospices Used by Medicare Advantage and Traditional Fee-for-Service Beneficiaries
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Transcutaneous Auricular Vagus Nerve Stimulation for Chronic Insomnia Disorder
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. ET, MONDAY, DECEMBER 16, 2024
Media advisory: The full study is linked to this news release.
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The results of this randomized clinical trial suggest that transcutaneous auricular vagus nerve stimulation would be safe and effective in treating chronic insomnia. Future multicenter clinical trials with large sample sizes are needed to validate its effectiveness across diverse populations.
Corresponding Authors: To contact the corresponding authors, email Yu Wang, MD, PhD, (wy8166@126.com) and Peijing Rong, MD, PhD, (drrongpj@163.com).
(doi:10.1001/jamanetworkopen.2024.51217)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Cannabidiol for Scan-Related Anxiety in Women With Advanced Breast Cancer
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. ET, MONDAY, DECEMBER 16, 2024
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.50391?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=121624
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The findings of this randomized clinical trial show that cannabidiol (CBD) can be used safely in women with advanced breast cancer and clinical anxiety. Although the study did not meet its primary end point comparing pre-ingestion vs post-ingestion anxiety change scores between study arms, anxiety levels in the CBD arm were significantly lower 2 to 4 hours after ingestion, suggesting a possible anxiolytic effect and warranting further investigation.
Corresponding Author: To contact the corresponding author, Ilana M. Braun, MD, email ilana_braun@dfci.harvard.edu.
(doi:10.1001/jamanetworkopen.2024.50391)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.
Daily Step Count and Depression in Adults
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. ET, MONDAY, DECEMBER 16, 2024
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.51208?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=121624
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this systematic review and meta-analysis of 33 observational studies involving 96,000 adults, higher daily step counts were associated with fewer depressive symptoms in cross-sectional and longitudinal studies in the general adult population. Further prospective cohort studies are needed to clarify the potential protective role of daily steps in mitigating the risk of depression during adulthood.
Corresponding Author: To contact the corresponding author, Estela Jimenez-Lopez, PhD, MPH, email estela.jimenezlopez@uclm.es.
(doi:10.1001/jamanetworkopen.2024.51208)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.
Loneliness and Social and Emotional Support Among Sexual and Gender Minority Caregivers
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.51931?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=121324
Polluted Air from Canadian Wildfires and Cardiopulmonary Disease in the Eastern US
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.50759?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=121324