US Workers’ Self-Reported Mental Health Outcomes by Industry and Occupation

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, JUNE 6, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this cross-sectional study, poor mental health among workers varied significantly by sociodemographic categories; significant differences among industry and occupation groups remained after adjustment. More research is needed on the effects of work-related factors on mental health, which may inform tailored treatment and prevention strategies.

Corresponding Author: To contact the corresponding author, Aaron L. Sussell, PhD, email als7@cdc.gov.

 

(doi:10.1001/jamanetworkopen.2025.14212)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Medigap Protection and Plan Switching Among Medicare Advantage Enrollees With Cancer

Posted by Jim Michalski

JAMA Health Forum

EMBARGOED FOR RELEASE: 5 P.M. (ET), SATURDAY, JUNE 7, 2025

Media advisory: The full study is linked to this news release. This study is being presented at the AcademyHealth 2025 Annual Research Meeting.

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About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

 

About The Study: In this cohort study, state Medigap guaranteed issue protections were associated with higher rates of switching to traditional Medicare among Medicare Advantage beneficiaries newly diagnosed with cancer. These findings underscore the protective association of state Medigap regulations in facilitating a switch to traditional Medicare (especially among beneficiaries who likely desired more flexibility in accessing and receiving care) and illuminate potential disparities in switching that may reflect unequal abilities to compare and afford plans.

Corresponding Author: To contact the corresponding author, Youngmin Kwon, PhD, email youngmin.kwon@vumc.org.

 

(doi:10.1001/jamahealthforum.2025.2018)

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Efficiency and Quality of Generative AI–Assisted Radiograph Reporting

Posted by Jim Michalski

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Economic Burden of Alzheimer Disease and Related Dementias by Race and Ethnicity, 2020 to 2060

Posted by Jim Michalski

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Health Care Workforce Recovery After the End of the COVID-19 Emergency

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 11:15 A.M. ET, THURSDAY, JUNE 5, 2025

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About The Study: Health care employment growth decreased amid the pandemic but fully recovered by 2024. This recovery contrasts with non–health care employment trends and may result from health care financing via insurance coverage shielding health care employment from macroeconomic fluctuations. 

Corresponding Author: To contact the corresponding author, Thuy Nguyen, PhD, email thuydn@umich.edu.

 

(doi:10.1001/jama.2025.8588)

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Glucagon-Like Peptide-1 Receptor Agonists and Risk of Neovascular Age-Related Macular Degeneration

Posted by Jim Michalski

JAMA Ophthalmology

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, JUNE 5, 2025

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Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaophthalmology/fullarticle/10.1001/jamaophthalmol.2025.1455?guestAccessKey=6090e38f-93ad-448f-aaff-ef4768286c5d&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=060525

 

About The Study: In this cohort study, the use of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) among patients with diabetes was associated with a 2-fold higher risk of incident neovascular age-related macular degeneration development than among similar patients with diabetes who did not receive a GLP-1 RA. Further research is needed to elucidate the exact pathophysiological mechanisms involved and to understand the trade-offs between the benefits and risks of GLP-1 RAs. 

Corresponding Author: To contact the corresponding author, Rajeev H. Muni, MD, MSc, email rajeev.muni@utoronto.ca.

 

(doi:10.1001/jamaophthalmol.2025.1455)

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BMI, Physical Activity, and Subsequent Neoplasm Risk Among Childhood Cancer Survivors

Posted by Jim Michalski

JAMA Oncology

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, JUNE 5, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaoncology/fullarticle/10.1001/jamaoncol.2025.1340?guestAccessKey=b428aebd-da70-4bcf-b3c2-afac5947e166&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=060525

 

About The Study: Among childhood cancer survivors in this cohort study, obesity was associated with an increased risk for multiple subsequent neoplasm types, while higher physical activity was associated with reduced subsequent neoplasm risk. Lifestyle interventions should be considered in future subsequent neoplasm prevention research.

Corresponding Author: To contact the corresponding author, Lenat Joffe, MD, MS, email ljoffe@northwell.edu.

 

(doi:10.1001/jamaoncol.2025.1340)

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AHA PREVENT Equations With Lipoprotein(a) and Risk Assessment for Primary Prevention

Posted by Jim Michalski

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Perceptions of Institutional Engagement and Inclusion by Sexual Orientation and Gender Identity

Posted by Jim Michalski

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Hypertension, Diabetes, and High Cholesterol Awareness Among US Adults

Posted by Jim Michalski

JAMA Cardiology

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, JUNE 4, 2025

Media advisory: The full study is linked to this news release.

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About The Study: The proportion of U.S. adults who were unaware of having hypertension increased significantly over the study period (2013 to 2023), particularly in young adults and women, while diabetes and high cholesterol level unawareness remained stable. By the 2021 to 2023 cycle, approximately 1 in 6 adults with hypertension and 3 in 10 with diabetes were unaware of their condition.

Corresponding Author: To contact the corresponding author, Rishi K. Wadhera, MD, MPP, MPhil, email rwadhera@bidmc.harvard.edu.

 

(doi:10.1001/jamacardio.2025.1536)

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Longitudinal Outcomes of the COVID-19 Pandemic on Youth Physical Fitness

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, JUNE 4, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this cohort study of schools, a COVID-19–related decline in youth physical fitness was observed. Compared with pre-pandemic and post-pandemic periods, cardiorespiratory fitness and musculoskeletal fitness healthy fitness zone achievement were significantly lower during the pandemic, but the reduction did not appear to be associated with extended remote or hybrid environments.

Corresponding Author: To contact the corresponding author, Andjelka Pavlovic, PhD, email andjelka.pavlovic@ttuhsc.edu.

 

(doi:10.1001/jamanetworkopen.2025.13721)

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Contribution of Modifiable Midlife and Late-Life Vascular Risk Factors to Incident Dementia

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaneurology/fullarticle/10.1001/jamaneurol.2025.1495?guestAccessKey=9f2f5c3e-4d60-4f88-8a54-2b9a44cb6cd2&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=060225

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Overall Survival and Quality-of-Life Superiority in Modern Phase 3 Oncology Trials

Posted by Jim Michalski

JAMA Oncology

EMBARGOED FOR RELEASE: 5:30 P.M. (ET), SUNDAY, JUNE 1, 2025

Media advisory: The full study and editor’s note are linked to this news release. This study is being presented at the 2025 American Society of Clinical Oncology Annual Meeting.

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About The Study: Although phase 3 trials are often interpreted as demonstrating superiority, overall survival and quality of life (QOL), which may be the most relevant end points to patients, are uncommonly improved. To increase the meaningfulness of late-phase research, future trial designs and regulatory processes should be refocused toward overall survival and QOL improvements.

Corresponding Author: To contact the corresponding author, Alexander D. Sherry, MD, email alexanderdsherry@gmail.com.

 

(doi:10.1001/jamaoncol.2025.1002)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Individual- and Area-Level Incarceration and Mortality

Posted by Alexandra Marusarz

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, JUNE 3, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: In this cohort study of 3.26 million individuals in the U.S., results highlighted the dual burden of incarceration on health outcomes. Individuals who were incarcerated faced significantly higher risks of death, particularly from overdoses, and elevated county incarceration rates exacerbated individual-level mortality risks. These findings suggest the need for reforms in criminal justice and public health policies to address these elevated risks and their widespread implications.

Corresponding author: To contact the corresponding author, Utsha G. Khatri, M.D., M.S., email utsha.khatri@mountsinai.org.

 

(doi: 10.1001/jamanetworkopen.2025.13537)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Severe Maternal Morbidity by Race and Ethnicity and Birth Mode

Posted by Alexandra Marusarz

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, JUNE 3, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: In this cross-sectional study of births among individuals with a prior cesarean birth, patterns of severe maternal morbidity (SMM) by birth mode varied by race and ethnicity, with elevated rates of SMM among those from marginalized racial and ethnic groups with planned cesarean births. Future work should identify interventions to improve quality of care and promote equity for this population.

Corresponding author: To contact the corresponding author, Laura B. Attanasio, Ph.D., email lattanasio@umass.edu.

 

(doi: 10.1001/jamanetworkopen.2025.13578)

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Clinical Validation of a Circulating Tumor DNA–Based Blood Test to Screen for Colorectal Cancer

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 11:15 A.M. ET, MONDAY, JUNE 2, 2025

Media advisory: The full study and editorial are linked to this news release.

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About The Study: In an average-risk colorectal cancer screening population, a blood-based test demonstrated acceptable accuracy for colorectal cancer detection, but detection of advanced precancerous lesions remains a challenge, and ongoing efforts are needed to improve test sensitivity. 

Corresponding Author: To contact the corresponding author, Theodore R. Levin, MD, email theodore.levin@kp.org.

 

(doi:10.1001/jama.2025.7515)

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Screening Colonoscopy Yields Among Adults Ages 45 to 49 After Lowering the Colon Cancer Screening Age

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 11:15 A.M. ET, MONDAY, JUNE 2, 2025

Media advisory: The full study is linked to this news release.

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About The Study: The finding of a slightly lower prevalence of any adenoma in the younger compared with the older age group (35.4% vs 40.8%) in the current study is consistent with an evaluation of 2001 screening colonoscopies from a university-based medical center between 2019 and 2021, which reported slightly lower rates of adenoma detection in those ages 45 to 49 vs 50 to 54 (34.3% vs 38.2%) and with a large study of adenoma detection rates in those ages 45 to 49 vs 50 to 54 (28.6% vs 31.8%) who underwent a screening colonoscopy before the change in guidelines (i.e., 2014-2020). 

Corresponding Author: To contact the corresponding author, Jeffrey K. Lee, MD, MPH, email jeffrey.k.lee@kp.org.

 

(doi:10.1001/jama.2025.7494)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Trends in County-Level MMR Vaccination Coverage in Children in the United States

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 11:15 A.M. ET, MONDAY, JUNE 2, 2025

Media advisory: The full study is linked to this news release.

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About The Study: This county-level dataset complements the state and national-level Centers for Disease Control and Prevention data, confirming a widespread decline in measles-mumps-rubella (MMR) vaccination rates in the U.S. after the COVID-19 pandemic while revealing significant heterogeneity in vaccination patterns within and across states. This dataset can be used in spatial and statistical analyses to identify factors associated with low or declining MMR rates in U.S. counties and help inform targeted vaccination strategies to reduce the risk of measles outbreaks. 

Corresponding Author: To contact the corresponding author, Lauren M. Gardner, PhD, email l.gardner@jhu.edu.

 

(doi:10.1001/jama.2025.8952)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Trends in Past-Month Cannabis Use Among Older Adults

Posted by Jim Michalski

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, JUNE 2, 2025

Media advisory: The full study and editor’s note are linked to this news release.  

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/10.1001/jamainternmed.2025.1156?guestAccessKey=bbd1a6af-2e2a-4b02-b44d-ea201d97515c&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=060225

 

About The Study: Between 2021 and 2023, prevalence of current cannabis use increased among adults age 65 or older nationally, with key demographic subgroups experiencing marked increases. Adults with the highest incomes initially had the lowest prevalence of cannabis use vs other income levels, but by 2023, they had the highest prevalence, which may indicate better access to medical cannabis given its costs. 

Corresponding Author: To contact the corresponding author, Benjamin H. Han, MD, email b2han@health.ucsd.edu.

 

(doi:10.1001/jamainternmed.2025.1156)

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Association of Endothelial Dysfunction With Chronic Marijuana Smoking and THC-Edible Use

Posted by Alexandra Marusarz

JAMA Cardiology

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, MAY 28, 2025

Media advisory: The full study is linked to this news release.

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About The Study: This cross-sectional study found that chronic cannabis smoking and tetrahydrocannabinol (THC) ingestion were associated with endothelial dysfunction similar to that observed in tobacco smokers, although apparently occurring via distinct mechanisms.

Corresponding author: To contact the corresponding author, Matthew L. Springer, Ph.D., email matt.springer@ucsf.edu.

 

(doi: 10.1001/jamacardio.2025.1399)

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Machine Learning for Predicting Critical Events Among Hospitalized Children

Posted by Jim Michalski

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Diversity Statements and Pediatric Residency Program and Department Characteristics

Posted by Jim Michalski

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Prevalence of Artificial Sweetener Neotame in US-Marketed Disposable E-Cigarettes

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 11 A.M. ET, MONDAY, JUNE 2, 2025

Media advisory: The full study is linked to this news release.

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About The Study: This study demonstrates that the artificial sweetener neotame was a ubiquitous constituent of popular disposable e-cigarettes sold in the U.S. in 2024, including those containing no nicotine or the nicotine analogue 6-methylnicotine. Neotame is 7,000 to 13,000 times sweeter than table sugar and is 35 to 65 times sweeter than aspartame.

Corresponding Author: To contact the corresponding author, Sven E. Jordt, PhD, email sven.jordt@duke.edu.

 

(doi:10.1001/jama.2025.7398)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Projected Outcomes of Removing Fluoride From US Public Water Systems

Posted by Jim Michalski

JAMA Health Forum

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, MAY 30, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama-health-forum/fullarticle/10.1001/jamahealthforum.2025.1166?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=053025

About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

 

About The Study: This cost-effectiveness analysis found that cessation of public water fluoridation would increase tooth decay and health system costs in the U.S. Despite concerns regarding toxic effects associated with high levels of fluoride, this model demonstrates the substantial ongoing benefits of water fluoridation at safe levels currently recommended by the U.S. Environmental Protection Agency, the National Toxicity Program, and the Centers for Disease Control and Prevention.

Corresponding Author: To contact the corresponding author, Lisa Simon, MD, DMD, email lsimon@bwh.harvard.edu.

 

(doi:10.1001/jamahealthforum.2025.1166)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Parental Education, Own Education, and Cognitive Function in Middle-Aged and Older Adults

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, MAY 30, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.13036?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=053025

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this cohort study of middle-aged and older adults across 4 countries, both higher maternal and paternal education were generally associated with slower cognitive decline, and these associations were mediated by participants’ own education. These findings highlight the long-term relevance of parental education for offspring cognitive health across diverse cultural or socioeconomic contexts, and support the potential benefits of improving educational attainment to reduce intergenerational disparities in late-life cognitive health.

Corresponding Author: To contact the corresponding author, Vivian Yawei Guo, PhD, email guoyw23@mail.sysu.edu.cn.

 

(doi:10.1001/jamanetworkopen.2025.13036)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Sacred Moment Experiences Among Internal Medicine Physicians

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, MAY 30, 2025

Media advisory: The full study and commentary are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.13159?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=053025

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this national survey of internal medicine physicians, experiencing sacred moments —meaningful, memorable, and sometimes spiritual moments of connection— is common; discussing them with colleagues is not. These findings suggest that frequently experiencing sacred moments and discussing them with colleagues could bolster physician well-being.

Corresponding Author: To contact the corresponding author, Jessica Ameling, MPH, email jameling@med.umich.edu.

 

(doi:10.1001/jamanetworkopen.2025.13159)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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New Definition of Light Chain Monoclonal Gammopathy of Undetermined Significance

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaoncology/fullarticle/10.1001/jamaoncol.2025.1285?guestAccessKey=eb418233-d244-41bc-ab61-62f924190392&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=052925

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Psychiatric Health Risks in North Korean Refugee Youths Resettled in South Korea

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.12941?guestAccessKey=576adde1-34aa-46c9-ace9-998c46b5ecf6&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=052925

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Prevalence Rates, Perceptions of Risk, and Motivations for Nonmedical Cannabis Use in Pediatric Pain

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.12870?guestAccessKey=0221e356-0c65-4b41-839c-5feddf40dbf1&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=052925

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Dedicated AI Expert System vs Generative AI With Large Language Model for Clinical Diagnoses

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.12994?guestAccessKey=245fc518-bb97-4420-8edb-4af88f41bc4a&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=052925

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Acupuncture for Nocturia in Survivors of Prostate Cancer

Posted by Jim Michalski

JAMA Oncology

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, MAY 29, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaoncology/fullarticle/10.1001/jamaoncol.2025.1199?guestAccessKey=76314b83-8573-4cfc-b733-28ac49d80ea1&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=052925

 

About The Study: In this pilot trial, acupuncture produced greater reductions in nocturia (waking up 1 or more times to urinate) relative to usual care in survivors of prostate cancer. The nocturia reduction was comparable to other treatments, such as desmopressin, α-blockers, and antimuscarinic medications; however, acupuncture was associated with fewer adverse events. Nocturia affects more than half of survivors of prostate cancer.

Corresponding Author: To contact the corresponding author, Kevin T. Liou, MD, email liouk@mskcc.org.

 

(doi:10.1001/jamaoncol.2025.1199)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Public Awareness of the Association Between Alcohol and Cancer in the US

Posted by Jim Michalski

JAMA Oncology

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, MAY 29, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaoncology/fullarticle/10.1001/jamaoncol.2025.1146?guestAccessKey=c798891c-b9a2-40de-9fea-0eae38926081&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=052925

 

About The Study: The findings of this study that fewer than half of U.S. adults are aware and about one-fifth are unsure of their awareness of the association between alcohol and cancer emphasize the need to implement the recently updated Surgeon General’s recommendation to reduce the alcohol-related cancer burden in the U.S.

Corresponding Author: To contact the corresponding author, Sanjay Shete, PhD, email sshete@mdanderson.org.

 

(doi:10.1001/jamaoncol.2025.1146)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Familiarity of the Surgeon-Anesthesiologist Dyad and Major Morbidity After High-Risk Elective Surgery

Posted by Alexandra Marusarz

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Childhood Maternal Warmth, Social Safety Schemas, and Adolescent Mental and Physical Health

Posted by Alexandra Marusarz

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time  https://jamanetwork.com/journals/jamapsychiatry/fullarticle/10.1001/jamapsychiatry.2025.0815?guestAccessKey=078d348e-5e45-42f5-a467-e1608fe53541utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=052825

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Early-Life Low Lead Levels and Academic Achievement in Childhood and Adolescence

Posted by Alexandra Marusarz

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, MAY 28, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.12796?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=052825

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: In this cohort study assessing early life low lead level and children’s and adolescents’ academic achievement, a 1-unit increase in lead levels in the range currently considered low for further interventions was associated with worse academic performance throughout school grades comparable to that for lead levels in the range recommended for additional interventions. These findings support the need to reconsider and potentially lower current blood lead reference values for recommending further interventions.

Corresponding author: To contact the corresponding author, George L. Wehby, M.P.H., Ph.D., email george-wehby@uiowa.edu.

 

(doi: 10.1001/jamanetworkopen.2025.12796)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Trends and Disparities in Maternal Self-Reported Mental and Physical Health

Posted by Jim Michalski

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Adverse Social Exposome During the Life Course and Vascular Brain Injury

Posted by Jim Michalski

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Asian American Female Residents’ Perceptions of Facilitators and Barriers to Leadership in Medicine

Posted by Jim Michalski

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Review and Publication Times and Reporting Across Journals on Health Policy

Posted by Jim Michalski

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Characterizing Long COVID Symptoms During Early Childhood

Posted by Jim Michalski

JAMA Pediatrics

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, MAY 27, 2025

Media advisory: The full study and Patient Page are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapediatrics/fullarticle/10.1001/jamapediatrics.2025.1066?guestAccessKey=9d614ff8-16bb-424b-b9f3-28dd1a7801f9&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=052725

 

About The Study: This cohort study identified symptom patterns and derived research indices that were distinct between the 2 age groups (infants/toddlers [0-2 years] vs preschool-aged children [3-5 years]) and differed from those previously identified in older ages, demonstrating the need to characterize long COVID separately across age ranges. 

Corresponding Author: To contact the corresponding author, Rachel S. Gross, MD, MS, email rachel.gross@nyulangone.org.

 

(doi:10.1001/jamapediatrics.2025.1066)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Patient-Delivered Continuous Care for Weight Loss Maintenance

Posted by Jim Michalski

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, MAY 27, 2025

Media advisory: The full study and commentary are linked to this news release.  

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/10.1001/jamainternmed.2025.1345?guestAccessKey=511e18fb-28e1-48cd-9f34-cb37dc7b1559&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=052725

 

About The Study: In this trial, patient-delivered lifestyle intervention (mentor interventionists plus peer support) yielded significantly better weight loss maintenance and cardiovascular risk outcomes compared with standard-of-care treatment delivered by professionals. Future research may examine the effectiveness of this novel treatment approach in community and clinical settings. 

Corresponding Author: To contact the corresponding author, Tricia M. Leahey, PhD, email tricia.leahey@uconn.edu.

 

(doi:10.1001/jamainternmed.2025.1345)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Weight Loss in Midlife, Chronic Disease Incidence, and All-Cause Mortality During Extended Follow-Up

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, TUESDAY, MAY 27, 2025

Media advisory: The full study and commentary are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.11825?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=052725

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this study, conducted when surgical and pharmacological weight-loss interventions were nearly nonexistent, sustained midlife weight loss compared with persistent overweight was associated with a decreased risk of chronic diseases beyond type 2 diabetes and decreased all-cause mortality.

Corresponding Author: To contact the corresponding author, Timo E. Strandberg, MD, PhD, email timo.strandberg@helsinki.fi.

 

(doi:10.1001/jamanetworkopen.2025.11825)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Global, Regional, and National Burden of Nontraumatic Subarachnoid Hemorrhage

Posted by Jim Michalski

JAMA Neurology

EMBARGOED FOR RELEASE: 4:30 A.M. (ET), FRIDAY, MAY 23, 2025

Media advisory: The full study is linked to this news release. This study is being presented at the European Stroke Organisation Conference 2025.

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https://jamanetwork.com/journals/jamaneurology/fullarticle/10.1001/jamaneurol.2025.1522?guestAccessKey=dc7baca4-ea3c-48e1-8ccd-feffbe71cb10&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=052325

 

About The Study: Although the global age-standardized burden rates of subarachnoid hemorrhage (SAH) more than halved over the last 3 decades, SAH remained one of the most common cardiovascular and neurological causes of death and disabilities in the world, with increasing absolute case numbers. These findings suggest evidence for the potential health benefits of proactive public health planning and resource allocation toward the prevention of SAH. Nontraumatic SAH represents the third most common stroke type after ischemic stroke and intracerebral hemorrhage, accounting for 5% to 10% of all strokes.

Corresponding Author: To contact the corresponding author, Ilari Rautalin, MD, PhD, email ilari.rautalin@aut.ac.nz.

 

(doi:10.1001/jamaneurol.2025.1522)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Excess US Deaths Before, During, and After the COVID-19 Pandemic

Posted by Jim Michalski

JAMA Health Forum

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, MAY 23, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama-health-forum/fullarticle/10.1001/jamahealthforum.2025.1118?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=052325

About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

 

About The Study: Between 1980 and 2023, the total number of excess U.S. deaths reached an estimated 14.7 million. Although excess deaths per year peaked in 2021, there were still more than 1.5 million during 2022 to 2023. In 2023, excess death rates remained substantially higher than pre-pandemic rates. The rising trend from 1980 to 2019 appears to have continued during and after the pandemic, likely reflecting pre-pandemic causes of death, including drug overdose, firearm injury, and cardiometabolic disease. These deaths highlight the continued consequences of U.S. health system inadequacies, economic inequality, and social and political determinants of health.

Corresponding Author: To contact the corresponding author, Jacob Bor, SD, email jbor@bu.edu.

 

(doi:10.1001/jamahealthforum.2025.1118)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Long-Term Follow-Up of Extracranial-Intracranial Bypass Surgery for Symptomatic Cerebral Artery Occlusion

Posted by Jim Michalski

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Tomosynthesis vs Digital Mammography Screening in Women with a Family History of Breast Cancer

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaoncology/fullarticle/10.1001/jamaoncol.2025.1209?guestAccessKey=d5f51a49-a143-4bbe-8417-c8b18ce8b808&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=052225

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Breast Cancer Outcomes in Transgender and Gender-Diverse Patients in the National Cancer Database

Posted by Jim Michalski

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Early-Life Factors and BMI Trajectories Among Children in the ECHO Cohort

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, MAY 22, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.11835?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=052225

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this cohort study of children in the Environmental influences on Child Health Outcomes (ECHO) cohort, analyses identified children on the path to obesity as early as age 3.5 years. Modifiable factors could be targeted for early prevention and intervention programs aimed at reducing childhood obesity.

Corresponding Author: To contact the corresponding author, Chang Liu, PhD, email c.liu@wsu.edu.

 

(doi:10.1001/jamanetworkopen.2025.11835)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Cardiac Events in Adults Hospitalized for RSV vs COVID-19 or Influenza

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, MAY 22, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this cross-sectional study, 1 in 10 patients hospitalized for respiratory syncytial virus (RSV) had a concurrent acute cardiovascular event. Odds of cardiac events were significantly higher in RSV vs COVID-19 hospitalizations in both vaccine-boosted and unboosted individuals. In contemporaneous hospitalizations for RSV or influenza after the pandemic (2023-2024), odds of heart failure were significantly higher in RSV hospitalizations vs vaccine-breakthrough influenza hospitalizations. These findings suggest that patients with preexisting cardiovascular risk should consider vaccination against respiratory viral infections.

Corresponding Author: To contact the corresponding author, Liang En Wee, MPH, email ian.wee.l.e@singhealth.com.sg.

 

(doi:10.1001/jamanetworkopen.2025.11764)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Clinical Outcomes of Laparoscopic vs Robotic-Assisted Cholecystectomy in Acute Care Surgery

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamasurgery/fullarticle/10.1001/jamasurg.2025.1291?guestAccessKey=9b48a1e3-6e10-45d9-8b48-62ac146e5071&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=052125

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Cannabis April 20th Celebration and Related Emergency Department Visits

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.11635?guestAccessKey=271f53e6-7902-47b1-9288-7bffd3615a18&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=052125

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Burden of Skin Cancer in Older Adults From 1990 to 2021 and Modelled Projection to 2050

Posted by Jim Michalski

JAMA Dermatology

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, MAY 21, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamadermatology/fullarticle/10.1001/jamadermatol.2025.1276?guestAccessKey=dc9cbe2b-fd6e-4cf7-9117-1cd69200a4eb&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=052125

 

About The Study: The older population (particularly male individuals and those living in high-sociodemographic index countries) is facing a substantial growing burden of skin cancer. Despite the relative incompleteness of keratinocyte cancer data and lack of race and ethnicity data, these results highlight the urgency for more effective prevention and management strategies targeting high-risk groups.

Corresponding Author: To contact the corresponding author, Jin Chen, PhD, email chenjin7791@163.com.

 

(doi:10.1001/jamadermatol.2025.1276)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

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Nutritional Content of Ready-to-Eat Breakfast Cereals Marketed to Children

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, MAY 21, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.11699?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=052125

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: Analysis of newly launched children’s ready-to-eat cereals from 2010 to 2023 revealed concerning nutritional shifts: notable increases in fat, sodium, and sugar alongside decreases in protein and fiber. Children’s cereals contain high levels of added sugar, with a single serving exceeding 45% of the American Heart Association’s daily recommended limit for children. These trends suggest a potential prioritization of taste over nutritional quality in product development, contributing to childhood obesity and long-term cardiovascular health risks.

Corresponding Authors: To contact the corresponding authors, email Shuoli Zhao, PhD, (szhao@uky.edu) and Qingxiao Li, PhD, (qli@agcenter.lsu.edu).

 

(doi:10.1001/jamanetworkopen.2025.11699)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Social Media Use and Depressive Symptoms During Early Adolescence

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, MAY 21, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.11704?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=052125

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this cohort study of more than 11,000 children and adolescents, reporting higher than person-level mean social media use in years 1 and 2 after baseline was associated with greater depressive symptoms in the subsequent year. The findings suggest that clinicians should provide anticipatory guidance regarding social media use for young adolescents and their parents.

Corresponding Author: To contact the corresponding author, Jason M. Nagata, MD, email Jason.nagata@ucsf.edu.

 

(doi:10.1001/jamanetworkopen.2025.11704)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Substance Use Screening, Brief Intervention, and Referral to Treatment Among Youth-Serving Clinicians

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, TUESDAY, MAY 20, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.11579?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=052025

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: The findings of this study suggest that while most clinicians report screening youths for substance use disorders at least sometimes, a substantial proportion screened only intermittently. Efforts to improve screening rates through education and systems-based practice changes may facilitate offering anticipatory guidance and substance use disorder treatment in all youth-serving clinical settings.

Corresponding Author: To contact the corresponding author, Kathleen Ragan-Burnett, MSPH, email xwy3@cdc.gov.

 

(doi:10.1001/jamanetworkopen.2025.11579)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Trends in Sedentary Behavior Among US Adults

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, MAY 21, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2025.7220?guestAccessKey=2c4b2d64-0e6f-4a61-99fa-73323f92103d&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=052125

 

About The Study: This study identified a promising trend of declining sedentary behavior among U.S. adults between 2013 and March 2020, but this decline was hampered in 2021-2023. Sedentary lifestyle was widely exacerbated during the COVID-19 pandemic, and this study highlights the enduring impact that this global pandemic may have on daily living patterns. 

Corresponding Author: To contact the corresponding author, Wei Bao, MD, PhD, email wbao@ustc.edu.cn.

 

(doi:10.1001/jama.2025.7220)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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A Multidimensional Diagnostic Approach for COPD

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 3 P.M. ET, SUNDAY, MAY 18, 2025

Media advisory: The full study and editorial are linked to this news release. This study is being presented at the American Thoracic Society International Conference.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2025.7358?guestAccessKey=0398b61f-6807-45b2-9dc7-71c2fd34136f&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=051825

 

About The Study: A new chronic obstructive pulmonary disease (COPD) diagnostic schema integrating respiratory symptoms, respiratory quality of life, spirometry, and structural lung abnormalities on computed tomographic imaging newly classified some individuals as having COPD. These individuals had an increased risk of all-cause and respiratory-related death, frequent exacerbations, and rapid lung function decline compared with individuals classified as not having COPD. Some individuals with airflow obstruction without respiratory symptoms or evidence of structural lung disease were no longer classified as having COPD. 

Corresponding Author: To contact the corresponding author, Surya P. Bhatt, MD, MSPH, email sbhatt@uabmc.edu.

 

(doi:10.1001/jama.2025.7358)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Long-Term Health Improvements and Economic Performance Among Individuals With Diabetes

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama-health-forum/fullarticle/10.1001/jamahealthforum.2025.0756?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=051625

About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

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Mental Health Trajectories Among US Survivors of Adolescent and Young Adult Cancer

Posted by Alexandra Marusarz

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, MAY 19, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.11430?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=051925

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: In this cohort study, survivors of adolescence and young adulthood cancer reported significantly worse mental health trajectories into middle or older adulthood, compared with individuals who experienced cancer as adults or never had it. Cancer clinicians should recognize the mental health burden for this population into middle age and older adulthood.

Corresponding author: To contact the corresponding author, Anao Zhang, Ph.D., email zhangan@med.umich.edu.

 

(doi: 10.1001/jamanetworkopen.2025.11430)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Antibiotic Treatment in Patients Hospitalized for Nonsevere COVID-19

Posted by Alexandra Marusarz

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, MAY 19, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.11499?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=051925

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: In this large cohort study of patients hospitalized with nonsevere COVID-19, there was no clinically meaningful difference in outcomes with early antibiotic treatment. Given the risks associated with unnecessary antibiotic treatment, these results argue against routine antibiotic use in this population.

Corresponding author: To contact the corresponding author, Michael S. Pulia, M.D., Ph.D., email mspulia@medicine.wisc.edu.

 

(doi: 10.1001/jamanetworkopen.2025.11499)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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