About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this retrospective multi-institutional study, patients who underwent surgery immediately preceding the weekend had a significantly increased risk of complications, readmissions, and mortality compared with those treated after the weekend. Further study is needed to understand differences in care that may underpin these observations and ensure that patients receive high-quality care regardless of the day of the week.
Corresponding author: To contact the corresponding author, Raj Satkunasivam, M.D., M.S., email raj.satkunasivam@gmail.com.
(doi: 10.1001/jamanetworkopen.2024.58794)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About The Study: In this evaluation of a place-based, coordinated, countywide intervention, reports of both substantiated and unsubstantiated child sexual abuse were shown to be significantly reduced at the population level.
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: This cross-sectional study found a recent increase in cervical cancer incidence in rural U.S. counties, specifically among white women. In addition, incidence was 25% higher and mortality was 42% higher in rural vs urban counties in recent years. The increase in incidence and mortality in rural U.S. counties may reflect lower screening coverage and lower utilization of diagnostic and therapeutic care, likely resulting from heightened access barriers experienced in rural areas. Additionally, if unaddressed, lower human papillomavirus (HPV) vaccine uptake in rural areas may contribute to further widening disparities in the future.
Corresponding Author: To contact the corresponding author, Trisha L. Amboree, PhD, MPH, email amboree@musc.edu.
(doi:10.1001/jamanetworkopen.2024.62634)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: A proposed U.S. Drug Enforcement Administration rule could impede buprenorphine initiation for a substantial number of patients with opioid use disorder. In this study, more than 4,500 tele-buprenorphine initiations from 2020 to 2022—20% of tele-initiations overall—would have been prohibited under requirements for an in-person visit with the tele-initiating clinician prior to or within 30 days after tele-initiation.
Corresponding Author: To contact the corresponding author, Emma E. McGinty, PhD, email emm4010@med.cornell.edu.
(doi:10.1001/jamanetworkopen.2025.0001)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: During the COVID-19 pandemic, food insecurity decreased among Supplemental Nutrition Assistance Program (SNAP) participants in most racial and ethnic groups but did not decrease among non-SNAP participants in any group. These results suggest that during the pandemic, increased SNAP benefit amounts were associated with ameliorating food insecurity for many U.S. adults who were able to access SNAP but did not reduce racial and ethnic disparities in food insecurity.
Corresponding Author: To contact the corresponding author, Yingfei Wu, MD, MPH, email yingfeiwu322@gmail.com.
(doi:10.1001/jamanetworkopen.2024.62277)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
About The Study: In this study, differences in out-of-pocket maternity spending among the commercially insured were associated with differences in coinsurance rates. These costs could lead people to forgo needed health care or other basic needs that support health (e.g., food or housing). Changes to health plan benefit design could improve equity in out-of-pocket maternity spending and its consequences.
Corresponding Author: To contact the corresponding author, Anna D. Sinaiko, PhD, MPP, email asinaiko@hsph.harvard.edu.
(doi:10.1001/jamahealthforum.2024.5565)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About The Study: This study found that the prevalence of adults with diabetes did not significantly change between 2013 and 2023, but glycemic control among those with diagnosed disease worsened in 2021-2023 after nearly a decade of stability. This trend was most pronounced among young adults. The increase of 1% in mean HbA1c levels and 20% decrease in glycemic control would increase the lifetime risk of cardiovascular events. Potential explanations for these findings include increased sedentary behavior, reduced social support, heightened mental health stressors, and limited access to health care and medications during the pandemic.
Corresponding Author: To contact the corresponding author, Rishi K. Wadhera, MD, MPP, MPhil, email rwadhera@bidmc.harvard.edu.
(doi:10.1001/jama.2024.28513)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this cohort study of 46,000 U.S. residents, nearly two-thirds of participants had suboptimal 5-year sleep duration trajectories. Suboptimal sleep duration trajectories were associated with as much as a 29% increase in risk of all-cause mortality. These findings highlight the importance of maintaining healthy sleep duration over time to reduce mortality risk.
Corresponding Author: To contact the corresponding author, Kelsie M. Full, PhD, MPH, email k.full@vumc.org.
(doi:10.1001/jamanetworkopen.2024.62117)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this cross-sectional study of U.S. homicide rates, substantial variation was found across and within county, race and ethnicity, sex, and age groups; American Indian and Alaska Native and Black males ages 15 to 44 had the highest rates of homicide. The findings highlight several populations and places where homicide rates were high, but awareness and violence prevention remains limited.
Corresponding Author: To contact the corresponding author, Paula D. Strassle, PhD, MSPH, email pdstrass@umd.edu.
(doi:10.1001/jamanetworkopen.2024.62069)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this cross-sectional study of social media posts about 5 popular medical tests, most posts were misleading or failed to mention important harms, including overdiagnosis or overuse. These data demonstrate a need for stronger regulation of misleading medical information on social media.
Corresponding Author: To contact the corresponding author, Brooke Nickel, PhD, email brooke.nickel@sydney.edu.au.
(doi:10.1001/jamanetworkopen.2024.61940)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this study, confidence in organizations to use health data responsibly was largely unchanged from 2020 to 2022, but polarization increased between politically liberal and conservative respondents. Compared with 2020, in 2022 liberal respondents reported increased confidence in the federal government to use digital health data responsibly, while conservative respondents reported decreased confidence in the federal government and agencies. Changes in confidence may be related to the prominence of these agencies (CDC, NIH) during the COVID-19 pandemic, a 2020 national election with a change in the governing political party, and political polarization.
Corresponding Author: To contact the corresponding author, Ravi Gupta, MD, MSHP, email ravigupta@jhmi.edu.
(doi:10.1001/jamanetworkopen.2024.61907)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About The Study: The findings of this study show a higher incidence of suicide for U.S. female physicians compared to female non-physicians. Comprehensive and multimodal suicide prevention strategies remain warranted.
Corresponding Author: To contact the corresponding author, Hirsh Makhija, MS, email himakhij@ucsd.edu.
(10.1001/jamapsychiatry.2024.4816)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About The Article: In May 2024, the American Law Institute approved its first-ever restatement of the law of medical malpractice, including new standards for resolving malpractice claims. This article describes the new legal standards and their significance for health professionals and organizations in 3 core areas: clinical care, communicating with patients, and the practice environment.
Corresponding Author: To contact the corresponding author, Christopher T. Robertson, JD, PhD, email ctr00@bu.edu.
(doi:10.1001/jama.2025.0097)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The findings of this study indicate that higher adherence to the Mediterranean diet is associated with a modest reduction in the risk of obesity-related cancers, independent of adiposity measures. Further research is needed to clarify the mechanisms by which the Mediterranean diet may contribute to cancer prevention.
Corresponding Author: To contact the corresponding author, Inmaculada Aguilera-Buenosvinos, PhD, email iaguilerabuenosvinos@gmail.com.
(doi:10.1001/jamanetworkopen.2024.61031)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About The Study: In this cohort study, telemedicine adoption was associated with modestly lower use of 7 of 20 examined low-value tests (most point-of-care) and no changes in use of other low-value tests, despite a small rise in total visits that might offer more testing opportunities. Results suggest possible benefits of telemedicine and mitigate concerns about telemedicine contributing to increased spending.
Corresponding Author: To contact the corresponding author, Ishani Ganguli, MD, MPH, email iganguli@bwh.harvard.edu.
(doi:10.1001/jamainternmed.2024.8354)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About The Study: The results of this cross-sectional study suggest that although physicians and most health care workers experienced lower mortality rates compared with the general population, this benefit did not fully extend to female individuals or racial and ethnic minority groups. Renewed efforts are needed to address health inequities within the health care workforce.
Corresponding Author: To contact the corresponding author, Anupam B. Jena, MD, PhD, email jena@hcp.med.harvard.edu.
(doi:10.1001/jamainternmed.2024.8432)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The results of this study suggest that mRNA COVID-19 vaccination may be a protective factor against post–COVID-19 condition in children following SARS-CoV-2 infection. These findings suggest benefits of COVID-19 vaccination beyond those associated with protection against acute COVID-19 and may encourage increased pediatric uptake.
Corresponding Author: To contact the corresponding author, Anna R. Yousaf, MD, email pgy6@cdc.gov.
(doi:10.1001/jamanetworkopen.2024.59672)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: This cohort study found no increase in sudden cardiac arrest/sudden cardiac death in young competitive athletes in the U.S. during the COVID-19 pandemic, suggesting that reports asserting otherwise were overestimating the cardiovascular risk of COVID-19 infection, vaccination, and myocarditis. Many athlete cases shown in social media video montages occurred before the pandemic yet claimed COVID-19 infection or vaccination raised the risk of sudden cardiac arrest/sudden cardiac death.
Corresponding Author: To contact the corresponding author, Jonathan A. Drezner, MD, email jdrezner@uw.edu.
(doi:10.1001/jamanetworkopen.2024.61327)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
About The Study: This study found persistent patterns of potentially aggressive care, but low uptake of supportive care, among Medicare decedents with advanced cancer. A multifaceted approach targeting patient-, physician-, and system-level factors associated with potentially aggressive care is imperative for improving quality of care at the end of life.
Corresponding Author: To contact the corresponding author, Youngmin Kwon, PhD, email youngmin.kwon@vumc.org.
(doi:10.1001/jamahealthforum.2024.5436)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this cohort study using a target trial emulation, a higher proportion of weight loss after initiating anti-obesity medications within 1 year was associated with a lower risk of 5-year and 10-year revision among patients with obesity undergoing joint replacement. These results suggest that anti-obesity medication use, with relatively safe and sustainable weight loss, may be an effective strategy for improving implant survivorship of hip and knee replacements in the obese population.
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this systematic review and dose-response meta-analysis, a daily 1-hour increment in digital screen time was associated with 21% higher odds of myopia (nearsightedness) and the dose-response pattern exhibited a sigmoidal shape, indicating a potential safety threshold of less than 1 hour per day of exposure, with an increase in odds up to 4 hours. These findings can offer guidance to clinicians and researchers regarding myopia risk.
Corresponding Author: To contact the corresponding author, Young Kook Kim, PhD, email md092@naver.com.
(doi:10.1001/jamanetworkopen.2024.60026)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: This cohort study found significant inequities in incidence of behavioral flags in the electronic health record among racially and socioeconomically marginalized pediatric patients. This finding was most pronounced for Black or African American patients younger than 8 years, suggesting that this phenomenon may be a response to Black families rather than specific patient behavior.
Corresponding Author: To contact the corresponding author, April Edwell, MD, MAEd, email April.edwell@ucsf.edu.
(doi:10.1001/jamanetworkopen.2024.61079)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About The Study: The results of this study suggest a modest increase in the risk of nonarteritic anterior ischemic optic neuropathy among individuals with type 2 diabetes associated with semaglutide use, smaller than that previously reported, and warranting further investigation into the clinical implications of this association.
Corresponding Author: To contact the corresponding author, Cindy X. Cai, MD, MS, email ccai6@jhmi.edu.
(doi:10.1001/jamaophthalmol.2024.6555)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The U.S. has achieved a new post-pandemic hospital occupancy steady state 11 percentage points higher than it was pre-pandemic. This persistently elevated occupancy appears to be driven by a 16% reduction in the number of staffed U.S. hospital beds rather than by a change in the number of hospitalizations. Experts in developed countries have posited that a national hospital occupancy of 85% constitutes a hospital bed shortage (a conservative estimate). The findings of the current study show that the U.S. could reach this dangerous threshold as soon as 2032, with some states at much higher risk than others.
Corresponding Author: To contact the corresponding author, Richard K. Leuchter, MD, email rleuchter@mednet.ucla.edu.
(doi:10.1001/jamanetworkopen.2024.60645)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About The Study: The findings of this study suggest that it is possible to predict diagnostic transition to schizophrenia and bipolar disorder from routine clinical data extracted from
electronic health records, with schizophrenia being notably easier to predict than bipolar disorder.
Corresponding Author: To contact the corresponding author, Lasse Hansen, MSc, PhD, email lasse.hansen@clin.au.dk.
(10.1001/jamapsychiatry.2024.4702)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About The Study: After more than 10 years of follow-up in the Swiss Multicenter Bypass or Sleeve Study randomized clinical trial, Roux-en-Y gastric bypass demonstrated superiority over sleeve gastrectomy for patient excess body mass index loss.
Corresponding Author: To contact the corresponding author, Ralph Peterli, MD, email ralph.peterli@clarunis.ch.
(doi:10.1001/jamasurg.2024.7052)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this survey study, disparities in tobacco use existed across cumulative disabilities. Despite declines in tobacco use over time, differences in use across cumulative disabilities persisted or worsened, especially among those with 3 or more disabilities. Targeted prevention, screening, and cessation efforts inclusive of multiple products are needed.
Corresponding author: To contact the corresponding author, Michael J. Parks, Ph.D., email Michael.parks@nih.gov.
(doi: 10.1001/jamanetworkopen.2024.60471)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: This cross-sectional study found a statistically significant increase in abortions for Colorado residents in association with the implementation of Texas SB8. This aligns with reports from area clinicians who experienced dramatic increases in patient demand after SB8, also reported by the media, resulting in delayed appointments for everyone.
Corresponding author: To contact the corresponding author, Kelly A. DeBie, J.D., email kelly.debie@colostate.edu.
(doi: 10.1001/jamanetworkopen.2024.60460)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About The Study: In a representative study of adults experiencing homelessness in California, there was a high proportion of current drug use, history of overdose, and unmet need for treatment. Improving access to treatment tailored to the needs of people experiencing homelessness could improve outcomes.
Corresponding Author: To contact the corresponding author, Ryan D. Assaf, PhD, MPH, email ryan.assaf@ucsf.edu.
(doi:10.1001/jama.2024.27922)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About The Editorial: The JAMA Network is publishing the results of four trials undertaken within the HEALEY amyotrophic lateral sclerosis (ALS) platform. The results are notable not because of therapeutic success—indeed, none of the interventions reached key end points—but because they represent the first platform trial results in ALS. Platform trials represent a departure from the familiar randomized clinical trial: different interventions targeting the same disease, in this case ALS, are studied concurrently within a common administrative and operational infrastructure (i.e., platform).
Corresponding Author: To contact the corresponding author, John Turnbull, M.D., Ph.D., email turnbull@mcmaster.ca.
(doi:10.1001/jama.2025.0100)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About The Article: This article discusses the regional variations in health care spending and the factors driving these differences.
(doi:10.1001/jama.2025.0072)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About The Study: Broad variation in health care spending was observed across U.S. counties. Understanding this variation by health condition, sex, age, type of care, and payer is valuable for identifying outliers, highlighting inequalities, and assessing health care gaps.
Corresponding Author: To contact the corresponding author, Joseph L. Dieleman, PhD, email dieleman@uw.edu.
(doi:10.1001/jama.2024.26790)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The findings of this cross-sectional study of Black and white women with breast cancer suggest that perceived stress, perceived inadequate social support, perceived racial and ethnic discrimination, and neighborhood deprivation were associated with deleterious alterations to the systemic and tumor immune environment, particularly for Black women. Understanding biology as a possible mediator of cancer health disparities may inform prevention and public health interventions.
Corresponding Author: To contact the corresponding author, Stefan Ambs, PhD, MPH, email ambss@mail.nih.gov.
(doi:10.1001/jamanetworkopen.2024.59754)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: This cohort study of Finnish children and adolescents found that higher physical activity and lower screen time from childhood were associated with perceived stress and depressive symptoms in adolescence. These findings emphasize reducing screen time and increasing physical activity to promote mental health in youth.
Corresponding Author: To contact the corresponding author, Eero A. Haapala, PhD, email eero.a.haapala@jyu.fi.
(doi:10.1001/jamanetworkopen.2024.60012)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
About The Study: In this cross-sectional study, variation in health care spending among U.S. counties was largely related to variation in service utilization. Understanding the drivers of spending variation in the U.S. may help policymakers assess the allocation of health care resources.
Corresponding Author: To contact the corresponding author, Joseph L. Dieleman, PhD, email dieleman@uw.edu.
(doi:10.1001/jamahealthforum.2024.5220)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About The Study: U.S. states that adopted abortion bans had higher than expected infant mortality after the bans took effect. The estimated relative increases in infant mortality were larger for deaths with congenital causes and among groups that had higher than average infant mortality rates at baseline, including Black infants and those in southern states.
Corresponding Author: To contact the corresponding author, Alison Gemmill, PhD, email agemmill@jhu.edu.
(doi:10.1001/jama.2024.28517)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About The Study: The findings of this study provide evidence that fertility rates in states with abortion bans were higher than would have been expected in the absence of these policies, with the largest estimated differences among subpopulations experiencing the greatest structural disadvantages and in states with among the worst maternal and child health and well-being outcomes.
Corresponding Author: To contact the corresponding author, Suzanne O. Bell, PhD, email suzannebell@jhu.edu.
(doi:10.1001/jama.2024.28527)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About The Study: From 2013-2014 to August 2021-August 2023, there were small increases in the percentage of children and adolescents with obesity, as well as in adults with severe obesity (but not obesity). There were no other significant changes in obesity-related measures, including waist circumference. This period included the COVID-19 pandemic; a study using electronic health records found a small increase in mean weight among adults during the pandemic.
Corresponding Author: To contact the corresponding author, Samuel D. Emmerich, DVM, email semmerich@cdc.gov.
(doi:10.1001/jama.2024.27676)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: Medicare Advantage-enrolled and commercially insured individuals were disproportionately more likely to use telehealth, with overall substance use disorder treatment (SUDT) increasing over time. Medicaid-covered individuals were underrepresented within telehealth SUDT utilization, with overall SUDT declining. This finding raises equity concerns for Medicaid populations. For rural individuals, telehealth may be reducing disparities, with overall SUDT increasing throughout the public health emergency to a greater extent than for urban individuals.
Corresponding Author: To contact the corresponding author, Lauryn Saxe Walker, PhD, MPH, email lauryn@vahealthinnovation.org.
(doi:10.1001/jamanetworkopen.2024.59606)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About The Study: The findings of this study provide initial prospective evidence that low-dose semaglutide can reduce craving and some drinking outcomes, justifying larger clinical trials to evaluate glucagon-like peptide 1 receptor agonists (GLP-1RAs) for alcohol use disorder.
Corresponding Author: To contact the corresponding author, Christian S. Hendershot, PhD, email christian.hendershot@usc.edu.
(10.1001/jamapsychiatry.2024.4789)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
