Gender Differences in Case Volume Among Ophthalmology Resident Graduates

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: In this cross-sectional study, commercial nontobacco nicotine use in U.S. 10th and 12th graders shifted from 2023 to 2024, marked by a doubling in nicotine pouch past-30-day use, an increase in pouch plus e-cigarette dual use, and a decrease in exclusive e-cigarette use. Prioritizing surveillance, regulation, and prevention addressing pediatric nicotine pouch use warrants consideration.

Corresponding Author: To contact the corresponding author, Adam M. Leventhal, PhD, email adam.leventhal@usc.edu.

(doi:10.1001/jamanetworkopen.2025.6739)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Wildfire Smoke Exposure and Cause-Specific Hospitalization in Older Adults

Posted April 28, 2025 by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, APRIL 30, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.7956?guestAccessKey=c0957767-f5eb-4d6d-88a4-15c747418b57&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=043025

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: Exposure to high levels of smoke pollution was associated with an increase in hospitalizations for respiratory diseases in this cohort study. These findings underscore the need for interventions to mitigate the health impacts of wildfire smoke exposure.

Corresponding Author: To contact the corresponding author, Rachel C. Nethery, PhD, email rnethery@hsph.harvard.edu.

(doi:10.1001/jamanetworkopen.2025.7956)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

AI-Enabled Screening for Retinopathy of Prematurity in Low-Resource Settings

Posted April 25, 2025 by Jim Michalski

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Consensus on Adolescent and Young Adult HIV Research Consent in Low- and Middle-Income Countries

Posted April 25, 2025 by Jim Michalski

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Long-Term Efficacy and Cost-Effectiveness of Laser Tonsillotomy vs Tonsillectomy

Posted April 25, 2025 by Jim Michalski

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Prenatal and Perinatal Factors of Life’s Essential 8 Cardiovascular Health Trajectories

Posted April 25, 2025 by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, TUESDAY, APRIL 29, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.7774?guestAccessKey=c0957767-f5eb-4d6d-88a4-15c747418b57&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042925

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: Pre-pregnancy overweight or obesity, smoking during pregnancy, and formula-feeding in the first 6 months of life were each associated with adverse cardiovascular health trajectories early in life in this cohort study. Future work should examine whether interventions that address these factors would be effective in optimizing cardiovascular health in children.

Corresponding Author: To contact the corresponding author, Izzuddin M. Aris, PhD, email izzuddin_aris@hphci.harvard.edu.

(doi:10.1001/jamanetworkopen.2025.7774)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Maternal Hypertension and Adverse Neurodevelopment in a Cohort of Preterm Infants

Posted April 25, 2025 by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, TUESDAY, APRIL 29, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.7788?guestAccessKey=c0957767-f5eb-4d6d-88a4-15c747418b57&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042925

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: In this preterm cohort study, maternal hypertensive disorders of pregnancy were independently associated with adverse cognitive and language development, with accentuated associations observed in preeclampsia-exposed preterm infants, emphasizing the clinical importance of recognizing hypertensive disorders of pregnancy as a risk, enabling targeted risk management strategies for closer monitoring and aggressive early intervention in affected populations.

Corresponding Author: To contact the corresponding author, Nehal A. Parikh, DO, MS, email nehal.parikh@cchmc.org.

(doi:10.1001/jamanetworkopen.2025.7788)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Menstrual Cycle Length Changes Following Vaccination Against Influenza Alone or With COVID-19

Posted April 25, 2025 by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, TUESDAY, APRIL 29, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.7871?guestAccessKey=c0957767-f5eb-4d6d-88a4-15c747418b57&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042925

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: In this cohort study of individuals with regular menstrual cycles, influenza vaccine given alone or in combination with a COVID-19 vaccine was associated with a small but temporary change in menstrual cycle length. These findings may help clinicians confirm the utility of vaccination for patients with concerns about menstrual adverse effects of vaccination.

Corresponding Author: To contact the corresponding author, Alison Edelman, MD, MPH, email edelmana@ohsu.edu.

(doi:10.1001/jamanetworkopen.2025.7871)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

The FDA’s Crisis Is Everyone’s Crisis

Posted April 24, 2025 by Jim Michalski

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Extended Caffeine for Apnea in Moderately Preterm Infants

Posted April 24, 2025 by Jim Michalski

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Temporal Trends in the Childhood Opportunity Index at Children’s Hospitals

Posted April 24, 2025 by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapediatrics/fullarticle/10.1001/jamapediatrics.2025.1041?guestAccessKey=3c0e1eb7-3668-4abe-884f-d68ae53540f9&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042725

Changes in Inhaled Steroid Dispensing to Children After Withdrawal of Brand-Name Fluticasone Propionate

Posted April 24, 2025 by Jim Michalski

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Active Treatment and Survival Trends for Periviable Births by Race and Ethnicity

Posted April 24, 2025 by Jim Michalski

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Toward Defining Problematic Media Usage Patterns in Adolescents

Posted April 24, 2025 by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 3:15 P.M. ET, MONDAY, APRIL 28, 2025

Media advisory: The full article is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2025.6113?guestAccessKey=fc50fd0f-5be4-45e1-a5df-7e2030dd1b61&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042825

About The Article: This Viewpoint proposes an analogous taxonomy for digital media use that identifies patterns of use, irrespective of content, that could be problematic but, at a minimum, should be flagged as warranting further evaluation and potential remediation.

Corresponding Author: To contact the corresponding author, Dimitri A. Christakis, MD, MPH, email dimitri.christakis@seattlechildrens.org.

(doi:10.1001/jama.2025.6113)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Trends in Maternal, Fetal, and Infant Mortality in the US, 2000-2023

Posted April 24, 2025 by Jim Michalski

JAMA Pediatrics

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, APRIL 28, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapediatrics/fullarticle/10.1001/jamapediatrics.2025.0440?guestAccessKey=6373041a-2cbe-4236-9947-287ec4b8491a&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042825

About The Study: The results of this study suggest that maternal health was difficult to track due to changes in reporting practices, but public health emergencies such as the COVID-19 pandemic can have large negative impacts.

Corresponding Author: To contact the corresponding author, Seth Flaxman, PhD, email seth.flaxman@cs.ox.ac.uk.

(doi:10.1001/jamapediatrics.2025.0440)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

All-Cause Mortality and Life Expectancy by Birth Cohort Across US States

Posted April 24, 2025 by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, MONDAY, APRIL 28, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.7695?guestAccessKey=c0957767-f5eb-4d6d-88a4-15c747418b57&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042825

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: Cohort-specific patterns across states reveal wide disparities in mortality. Some states have experienced little or no improvements in life expectancy from the 1900 to 2000 birth cohorts. Understanding how mortality patterns vary by birth cohort within each state can inform decision-making around resource allocation and public health interventions.

Corresponding Author: To contact the corresponding author, Theodore R. Holford, PhD, email theodore.holford@yale.edu.

(doi:10.1001/jamanetworkopen.2025.7695)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Uptake of and Disparities in Semaglutide and Tirzepatide Prescribing for Obesity in the US

Posted April 24, 2025 by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 11 A.M. ET, TUESDAY, APRIL 29, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2025.4735?guestAccessKey=ba29174d-ce24-48f3-926b-02e03bb82ad6&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042925

About The Study: Semaglutide and tirzepatide prescriptions within Epic-affiliated health care systems increased slightly between 2021 and 2024, but their uptake remained limited, with only 3% of eligible patients having ever received a prescription during that period. Furthermore, there were disparities in prescribing of varying magnitude based on race and ethnicity, social vulnerability, and urbanicity, although the absolute differences were small compared with the overall underutilization.

Corresponding Author: To contact the corresponding author, Yuan Lu, ScD, email y.lu@yale.edu.

(doi:10.1001/jama.2025.4735)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Buprenorphine Treatment in Pregnancy and Maternal-Infant Outcomes

Posted April 24, 2025 by Jim Michalski

JAMA Health Forum

EMBARGOED FOR RELEASE: 4:45 P.M. (ET), SUNDAY, APRIL 27, 2025

Media advisory: The full study is linked to this news release. This study is being presented at the Pediatric Academic Societies 2025 meeting.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama-health-forum/fullarticle/10.1001/jamahealthforum.2025.1814?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=042725

About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

About The Study: In this cohort study of pregnant individuals with opioid use disorder, buprenorphine treatment was associated with improved outcomes for the mother and infant, underscoring the need to improve access to treatment nationwide.

Corresponding Author: To contact the corresponding author, Stephen W. Patrick, MD, MPH, MS, email stephen.patrick@emory.edu.

(doi:10.1001/jamahealthforum.2025.1814)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Alcohol Use Disorder Diagnoses Among Individuals Who Take HIV Preexposure Prophylaxis

Posted April 23, 2025 by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.7295?guestAccessKey=925562d9-557d-4f24-9cf6-f9ffc64caf05&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042525

Lung Function Trajectory Using Race-Specific vs Race-Neutral Global Lung Function Initiative Coefficients

Posted April 23, 2025 by Jim Michalski

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Geographic Variation of Racial and Ethnic Differences in Uterine Cancer Survival

Posted April 23, 2025 by Jim Michalski

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Public Coverage of Postpartum Services for Immigrants

Posted April 23, 2025 by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama-health-forum/fullarticle/10.1001/jamahealthforum.2025.0702?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=042525

About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

State and Sociodemographic Trends in US Cigarette Smoking With Future Projections

Posted April 23, 2025 by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, APRIL 25, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.6834?guestAccessKey=c0957767-f5eb-4d6d-88a4-15c747418b57&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042525

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: The findings of these repeated cross-sectional surveys suggest that the difference in cigarette smoking prevalence between historically high vs low prevalence states will shrink by 2035, primarily from much faster declines among young adults in the traditionally highest prevalence states. Slower prevalence declines among older adults are likely to slow the decline in health consequences in these states.

Corresponding Author: To contact the corresponding author, John P. Pierce, PhD, email jppierce@health.ucsd.edu.

(doi:10.1001/jamanetworkopen.2025.6834)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

# # #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Fiscal Impact of Expanded Medicare Coverage for GLP-1 Receptor Agonists to Treat Obesity

Posted April 23, 2025 by Jim Michalski

JAMA Health Forum

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, APRIL 25, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama-health-forum/fullarticle/10.1001/jamahealthforum.2025.0905?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=042525

About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

About The Study: This economic evaluation estimates that expanded Medicare coverage for glucagon-like peptide-1 receptor agonists (GLP-1RAs) would increase access and reduce obesity-related comorbidities but impose substantial costs over 10 years. Even with a moderate scenario (5% uptake, 20% adherence, and 30% additional price discount), net spending was still projected to reach $8 billion over a decade, underscoring the need for further price reductions, lower-cost strategies to prevent weight regain, and reductions in spending on low-value care.

Corresponding Author: To contact the corresponding author, David D. Kim, PhD, email david.kim@bsd.uchicago.edu.

(doi:10.1001/jamahealthforum.2025.0905)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Modeling Reemergence of Vaccine-Eliminated Infectious Diseases Under Declining Vaccination in the US

Posted April 23, 2025 by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 11:15 A.M. ET, THURSDAY, APRIL 24, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time

https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2025.6495?guestAccessKey=4760b098-4441-478b-8eb5-7009d702a227&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042425

About The Study: Based on estimates from this modeling study, declining childhood vaccination rates will increase the frequency and size of outbreaks of previously eliminated vaccine-preventable infections, eventually leading to their return to endemic levels. The timing and critical threshold for returning to endemicity will differ substantially by disease, with measles likely to be the first to return to endemic levels and may occur even under current vaccination levels without improved vaccine coverage and public health response. These findings support the need to continue routine childhood vaccination at high coverage to prevent resurgence of vaccine-preventable infectious diseases in the U.S.

Corresponding Author: To contact the corresponding author, Nathan C. Lo, MD, PhD, email nathan.lo@stanford.edu.

(doi:10.1001/jama.2025.6495)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Race, Ethnicity, and Outcomes Among Adults With Atrial Fibrillation Treated With Drug Therapy vs Ablation

Posted April 22, 2025 by Jim Michalski

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Characteristics of Medical Cannabis Patients and Clinicians in 7 US States

Posted April 22, 2025 by Jim Michalski

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Patient-Centered Research Through AI to Identify Priorities in Cancer Care

Posted April 22, 2025 by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaoncology/fullarticle/10.1001/jamaoncol.2025.0694?guestAccessKey=e3559e1c-aa15-4e43-8fd3-1cb6a8890274&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042425

Intravenous Magnesium and Cisplatin-Associated Acute Kidney Injury

Posted April 22, 2025 by Jim Michalski

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Herpes Zoster Vaccination and Dementia Occurrence

Posted April 22, 2025 by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 4:40 P.M. ET, WEDNESDAY, APRIL 23, 2025

Media advisory: The full study is linked to this news release. This study is being presented at the World Vaccine Congress.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2025.5013?guestAccessKey=f9b03e5d-4caa-4a0c-a7cf-bdbe9c25154a&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042325

About The Study: By taking advantage of a quasi-experiment and corroborating findings from Wales in a different population, this study provides evidence of the potential benefits of herpes zoster vaccination for dementia that is more likely to be causal than that of more commonly conducted associational studies.

Corresponding Author: To contact the corresponding author, Pascal Geldsetzer, ScD, MBChB, MPH, email pgeldsetzer@stanford.edu.

(doi:10.1001/jama.2025.5013)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Metformin for Knee Osteoarthritis in Patients With Overweight or Obesity

Posted April 22, 2025 by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 7:45 P.M. ET, THURSDAY, APRIL 24, 2025

Media advisory: The full study is linked to this news release. This study is being presented at the Osteoarthritis Research Society International World Congress.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2025.3471?guestAccessKey=311f6f13-a737-426e-8e68-921fffe73bfb&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042425

About The Study: The results of this randomized clinical trial support use of metformin for treatment of symptomatic knee osteoarthritis in people with overweight or obesity. Because of the modest sample size, confirmation in a larger clinical trial is warranted.

Corresponding Author: To contact the corresponding author, Flavia M. Cicuttini, PhD, email flavia.cicuttini@monash.edu.

(doi:10.1001/jama.2025.3471)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Trends in Mental Health Diagnoses Among Publicly Insured Children

Posted April 22, 2025 by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, APRIL 24, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2025.4605?guestAccessKey=de6371be-8acf-4752-9f5b-d1f3c25f529b&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042425

About The Study: The percentage of publicly insured children receiving any mental health or neurodevelopmental disorder diagnosis significantly increased between 2010 and 2019, with increases observed for most diagnostic categories examined. These findings highlight the need for access to appropriate services in safety net systems and other settings that serve this population.

Corresponding Author: To contact the corresponding author, Janet R. Cummings, PhD, email jrcummi@emory.edu.

(doi:10.1001/jama.2025.4605)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Health Care Cost Concerns and Hardships for Families of Children With Disabilities

Posted April 22, 2025 by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, APRIL 24, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.7826?guestAccessKey=c0957767-f5eb-4d6d-88a4-15c747418b57&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042425

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: This study contributes to the existing literature by identifying that while insurance coverage is higher among children with disabilities, their families had higher adjusted odds for all of the financial hardships evaluated, compared with families of children without disabilities. This finding suggests that insurance is inadequate for disabled children. These data demonstrate a need to structure health insurance policies to ensure that children with disabilities have their needed medical care covered in a way that is not financially burdensome to families.

Corresponding Author: To contact the corresponding author, Amy J. Houtrow, MD, PhD, MPH, email houtrow@upmc.edu.

(doi:10.1001/jamanetworkopen.2025.7826)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Cumulative Life’s Essential 8 Scores and Cardiovascular Disease Risk

Posted April 21, 2025 by Jim Michalski

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Distinct Convergent Brain Alterations in Sleep Disorders and Sleep Deprivation

Posted April 21, 2025 by Jim Michalski

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Long-Term Postoperative Outcomes by Surgeon Gender and Patient-Surgeon Gender Concordance in the US

Posted April 21, 2025 by Jim Michalski

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Cannabis Use and Misuse Following Recreational Cannabis Legalization

Posted April 21, 2025 by Jim Michalski

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Sense of Belonging and Intent to Leave Among Medical School Faculty

Posted April 21, 2025 by Jim Michalski

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Cognitive and Functional Decline Among Long-Term Care Residents

Posted April 21, 2025 by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, APRIL 23, 2025

Media advisory: The full study and commentary are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.5635?guestAccessKey=c0957767-f5eb-4d6d-88a4-15c747418b57&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042325

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: In this study, severe permanent impairment in function and cognition were common and often present near the end of life for long-term care residents, but a minority of residents lived in these states for years. These results suggest that building shared understanding and open communication about the natural course of frailty trajectories for long-term care residents may support resident-centered medical decision-making.

Corresponding Author: To contact the corresponding author, Daniel Kobewka, MD, MSc, email dkobewka@toh.ca.

(doi:10.1001/jamanetworkopen.2025.5635)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

# # #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Screening and Response for Adverse Social Determinants of Health in US Emergency Departments

Posted April 21, 2025 by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, APRIL 23, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.7951?guestAccessKey=c0957767-f5eb-4d6d-88a4-15c747418b57&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042325

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: Despite the high prevalence of adverse social determinants of health (SDOH) in emergency department (ED) populations, in this survey study of 232 EDs, less than one-third performed screening, and one-fifth did not have policies requiring a response to positive screens. Bridging this gap may require expanding adverse SDOH screening practices while also ensuring that EDs have the resources and infrastructure to respond appropriately to identified social needs. Future research might explore advanced technological solutions to enhance screening and responses in these resource-constrained settings.

Corresponding Author: To contact the corresponding author, Melanie F. Molina, MD, MAS, email melanie.molina@ucsf.edu.

(doi:10.1001/jamanetworkopen.2025.7951)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

# # #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Alcohol Use and Abusive or Neglectful Behaviors Among Family Caregivers of Patients With Dementia

Posted April 18, 2025 by Alexandra Marusarz

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, APRIL 22, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.6211?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=042225

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: In this microlongitudinal cohort study of family caregivers of relatives with dementia, hazardous drinking and daily alcohol consumption were significantly and independently associated with increased odds of abusive and neglectful behaviors, highlighting the need for personalized interventions that address caregiving complexities and alcohol use patterns.

Corresponding author: To contact the corresponding author, Carolyn E. Z. Pickering, Ph.D., R.N., email pickering@uth.tmc.edu.

(doi: 10.1001/jamanetworkopen.2025.6211)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Nurse Staffing Configurations and Nurse Absence Due to Sickness

Posted April 18, 2025 by Alexandra Marusarz

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Prevalence of Impairing Substance Use in Injured Drivers

Posted April 18, 2025 by Alexandra Marusarz

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Patterns in Symptoms Preceding Acute Care in Patients With Cancer

Posted April 18, 2025 by Alexandra Marusarz

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Childhood Exposure to Air Pollution, BMI Trajectories, and Insulin Resistance Among Young Adults

Posted April 18, 2025 by Alexandra Marusarz

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, APRIL 22, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.6431?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=042225

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: In this cohort study of young adults, the long-term association between traffic-related air pollution and insulin resistance may be partially explained by higher body mass index (BMI) and accelerated BMI growth from early adolescence into young adulthood. These findings highlight the importance of weight management in children, particularly those residing in highly polluted areas.

Corresponding author: To contact the corresponding author, Shohreh F. Farzan, Ph.D., email sffarzan@usc.edu.

(doi: 10.1001/jamanetworkopen.2025.6431)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

# # #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Varenicline for Youth Nicotine Vaping Cessation

Posted April 18, 2025 by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, APRIL 23, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2025.3810?guestAccessKey=8c0aa836-0f6d-465e-86ea-178fe0d81e70&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042325

About The Study: In this 12-week randomized clinical trial, varenicline, combined with behavioral counseling, increased vaping abstinence in youth who vape nicotine and do not regularly smoke tobacco.

Corresponding Author: To contact the corresponding author, A. Eden Evins, MD, email aeevins@mgh.harvard.edu.

(doi:10.1001/jama.2025.3810)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Cytisinicline for Smoking Cessation

Posted April 17, 2025 by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/10.1001/jamainternmed.2025.0628?guestAccessKey=1e0c0244-2e30-421f-92a9-0932cb6f45f3&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042125

Genomic and Developmental Models to Predict Cognitive and Adaptive Outcomes in Autistic Children

Posted April 17, 2025 by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapediatrics/fullarticle/10.1001/jamapediatrics.2025.0205?guestAccessKey=0dc639e3-fd1b-4e8e-a46a-5ea0c796aa05&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042125

Obstetrician and Gynecologist Physicians’ Practice Locations Before and After the Dobbs Decision

Posted April 17, 2025 by Jim Michalski

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Surgical Outcomes and Patient Expectations and Satisfaction in Spine Surgery Stratified by Surgeon Age

Posted April 17, 2025 by Jim Michalski

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Medication for Opioid Use Disorder and Treatment Retention Among Pregnant Individuals

Posted April 17, 2025 by Jim Michalski

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Trends in Mental and Physical Health Among Youths

Posted April 17, 2025 by Jim Michalski

JAMA Pediatrics

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, APRIL 21, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapediatrics/fullarticle/10.1001/jamapediatrics.2025.0556?guestAccessKey=39cacfb2-9054-4750-a142-6a7353a21871&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042125

About The Study: In this large, nationally representative sample of U.S. youths, the proportions of youths with anxiety or depression increased from 2016 to 2022. In contrast, youth physical health conditions like asthma and severe headache or migraine decreased, while behavioral or conduct problems and heart conditions were consistent. These findings suggest that deterioration in youth health was specific to depression and anxiety but not select physical health conditions. This study aimed to characterize trends in youth health in the U.S., but more work is needed to identify factors associated with observed trends and mechanisms associated with changes.

Corresponding Author: To contact the corresponding author, Marie E. Heffernan, PhD, email mheffernan@luriechildrens.org.

(doi:10.1001/jamapediatrics.2025.0556)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Transcranial Pulsed Current Stimulation and Social Functioning in Children With Autism

Posted April 17, 2025 by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, MONDAY, APRIL 21, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.5776?guestAccessKey=c0957767-f5eb-4d6d-88a4-15c747418b57&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042125

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: In this randomized clinical trial of prefrontal-cerebellar transcranial pulsed current stimulation in children ages 3 to 14 with autism spectrum disorder, 20 sessions over 4 weeks improved social functioning and sleep. These findings suggest that transcranial pulsed current stimulation may serve as a viable nonpharmacologic alternative for autism spectrum disorder.

Corresponding Author: To contact the corresponding author, Zhenhuan Liu, MD, PhD, email lzh1958424@163.com.

(doi:10.1001/jamanetworkopen.2025.5776)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Burnout Trends Among US Health Care Workers

Posted April 17, 2025 by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, MONDAY, APRIL 21, 2025

Media advisory: The full study and commentary are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.5954?guestAccessKey=c0957767-f5eb-4d6d-88a4-15c747418b57&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042125

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: In this survey study of Veterans Health Administration (VHA) health care workers, burnout and professional stress decreased on average following the pandemic, but burnout levels remain elevated compared with prepandemic levels. The VHA has made several efforts to reduce burnout and stress, and results showed some promise, but exploration of ways to reduce burnout to prepandemic levels is needed.

Corresponding Author: To contact the corresponding author, David C. Mohr, PhD, email david.mohr2@va.gov.

(doi:10.1001/jamanetworkopen.2025.5954)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Non–Risk-Based Lung Cancer Screening With Low-Dose Computed Tomography

Posted April 16, 2025 by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2025.4017?guestAccessKey=adce1d94-5f5d-41bc-8fb4-39d5d79d67ee&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042125

Development and Assessment of a Patient-Reported Outcome Instrument for Gender-Affirming Care

Posted April 16, 2025 by Jim Michalski

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Mental and Physical Health-Related Risk Factors Among Females Who Died by Firearm Suicide

Posted April 16, 2025 by Jim Michalski

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Genetic and Nongenetic Risk Factors for Breast Cancer Risk Estimation

Posted April 16, 2025 by Jim Michalski

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Medical Debt and Forgone Mental Health Care Due to Cost Among Adults

Posted April 16, 2025 by Jim Michalski

JAMA Health Forum

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, APRIL 18, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama-health-forum/fullarticle/10.1001/jamahealthforum.2025.0383?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=041825

About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

About The Study: In this survey study, more than 1 in 7 adults reported carrying medical debt in 2023, of whom 1 in 3 forwent mental health care in the subsequent year. Medical debt may exacerbate the treatment gap by potentially (1) raising the threshold for seeking care, (2) eroding patient trust in the health system, or (3) being denied care due to outstanding debts.

Corresponding Author: To contact the corresponding author, Catherine K. Ettman, PhD, email cettman1@jh.edu.

(doi:10.1001/jamahealthforum.2025.0383)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

# # #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Legalizing Youth-Friendly Cannabis Edibles and Extracts and Adolescent Cannabis Use

Posted April 16, 2025 by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, APRIL 18, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.5819?guestAccessKey=c0957767-f5eb-4d6d-88a4-15c747418b57&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=041825

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: In this serial cross-sectional study of adolescents in grades 7 to 11, legalization of cannabis edibles and extracts was associated with an increase not only in edible cannabis use and cannabis smoking, but also in the overall prevalence of cannabis use and co-use of alcohol and cannabis, highlighting the need for stricter policy measures to curb adolescents’ access to cannabis edibles and extracts and greater awareness among adolescents about harms of cannabis use.

Corresponding Author: To contact the corresponding author, Hai V. Nguyen, PhD, email hvnguyen@mun.ca.

(doi:10.1001/jamanetworkopen.2025.5819)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

# # #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Self- and Informant-Report Cognitive Decline Discordance and Mild Cognitive Impairment Diagnosis

Posted April 16, 2025 by Jim Michalski

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Disparities in Digital Health Care Use in 2022

Posted April 15, 2025 by Jim Michalski

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Health-Related Quality of Life in the US Territories of Puerto Rico, Guam, and the Virgin Islands

Posted April 15, 2025 by Jim Michalski

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Inequity in Assessment Among Pediatric Residents

Posted April 15, 2025 by Jim Michalski

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Population Attributable Fraction of Incident Dementia Associated With Hearing Loss

Posted April 15, 2025 by Jim Michalski

JAMA Otolaryngology–Head & Neck Surgery

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, APRIL 17, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaotolaryngology/fullarticle/10.1001/jamaoto.2025.0192?guestAccessKey=38b318ae-1b2b-43e1-b055-f2cb0ea40274&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=041725

About The Study: The results of this cohort study suggest that treating hearing loss might delay dementia for a large number of older adults. Public health interventions targeting clinically significant audiometric hearing loss might have broad benefits for dementia prevention. Future research quantifying population attributable fractions should carefully consider which measures are used to define hearing loss, as self-reporting may underestimate hearing-associated dementia risk.

Corresponding Author: To contact the corresponding author, Jason R. Smith, ScM, email jsmit491@jhu.edu.

(doi:10.1001/jamaoto.2024.0192)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Prevalence of Obesity With and Without Confirmation of Excess Adiposity Among US Adults

Posted April 15, 2025 by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, APRIL 17, 2025

Media advisory: The full study is linked to this news release.

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About The Study: Among U.S. adults ages 20 to 59, the prevalence of obesity by body mass index (BMI) only was nearly identical with the obesity prevalence after confirmation of excess adiposity. Approximately 98% of individuals identified as having obesity based on BMI had excess adiposity.

Corresponding Author: To contact the corresponding author, Michael Fang, PhD, MHS, email mfang9@jh.edu.

(doi:10.1001/jama.2025.2704)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Digital Photography Guide for Dermatologists With Special Considerations for Diverse Populations

Posted April 14, 2025 by Jim Michalski

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Cognitive Behavior Therapy for Mental Disorders in Adults

Posted April 14, 2025 by Jim Michalski

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Negative Effects During Placebo Treatment

Posted April 14, 2025 by Jim Michalski

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Preferences for Communication About Prognosis Among Children With Cancer, Parents, and Oncologists

Posted April 14, 2025 by Jim Michalski

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AI–Enabled Prediction of Heart Failure Risk From Single-Lead Electrocardiograms

Posted April 14, 2025 by Jim Michalski

JAMA Cardiology

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, APRIL 16, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamacardiology/fullarticle/10.1001/jamacardio.2025.0492?guestAccessKey=aadc3c8c-03cf-4e4b-9b5a-4e521211870b&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=041625

About The Study: Across multinational cohorts, a noise-adapted artificial intelligence (AI)-electrocardiogram (ECG) model estimated heart failure risk using lead I ECGs, suggesting a potential heart failure risk-stratification strategy requiring prospective study using wearable and portable ECG devices.

Corresponding Author: To contact the corresponding author, Rohan Khera, MD, MS, email rohan.khera@yale.edu.

(doi:10.1001/jamacardio.2025.0492)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflicts of interest and financial disclosures, and funding and support.

# # #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Immediate Skin-to-Skin Contact in Very Preterm Neonates and Early Childhood Neurodevelopment

Posted April 14, 2025 by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, APRIL 16, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.5467?guestAccessKey=c0957767-f5eb-4d6d-88a4-15c747418b57&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=041625

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: In this randomized clinical trial, 2 hours of mother-neonate skin-to-skin contact (SSC) in the delivery room did not enhance neurodevelopmental outcomes at 2 to 3 years of age. However, the SSC group demonstrated improved breastfeeding practices up to 12 months compared with standard care, suggesting that the feasible and low-cost SSC intervention should be encouraged in clinical practice.

Corresponding Author: To contact the corresponding author, Laila Kristoffersen, RN, PhD, email laila.kristoffersen@ntnu.no.

(doi:10.1001/jamanetworkopen.2025.5467)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

# # #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Social Risk at Individual vs Neighborhood Levels and Health Care Use in Medicaid Enrollees

Posted April 11, 2025 by Jim Michalski

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Plastic Waste and COVID-19 Incidence Among Hospital Staff After Deescalation in PPE Use

Posted April 11, 2025 by Jim Michalski

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Rurality and Area Deprivation and Outcomes After Out-of-Hospital Cardiac Arrest

Posted April 11, 2025 by Jim Michalski

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Screening History, Stage at Diagnosis, and Mortality in Screen-Detected Breast Cancer

Posted April 11, 2025 by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, TUESDAY, APRIL 15, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.5322?guestAccessKey=c0957767-f5eb-4d6d-88a4-15c747418b57&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=041525

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: In this cohort study of older women with screen-detected estrogen receptor–positive or human epidermal growth factor receptor 2–negative breast cancer, prior screening mammography was associated with earlier stage at breast cancer diagnosis and lower breast cancer mortality. These findings support the potential for routine screening to improve breast cancer outcomes. As with all observational studies, this study is limited by the potential effects of other differences between the screening and nonscreening groups.

Corresponding Author: To contact the corresponding author, Michaela A. Dinan, PhD, email michaela.dinan@yale.edu.

(doi:10.1001/jamanetworkopen.2025.5322)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Sex-Based Differences in Binge and Heavy Drinking Among US Adults

Posted April 11, 2025 by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, APRIL 16, 2025

Media advisory: The full study is linked to this news release.

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About The Study: This analysis found that past-month binge drinking among young adult females in 2021-2023 was higher than males, reversing 2017-2019 patterns, whereas males in other age groups continued to binge and heavy drink at higher rates. These findings may be due to more rapid decreases in binge drinking over time among young adult males relative to females, or to plateauing or increases in binge drinking among females. Further investigation using other nationally representative surveys is needed to elucidate these explanations.

Corresponding Author: To contact the corresponding author, Bryant Shuey, MD, MPH, email bryant.shuey@pitt.edu.

(doi:10.1001/jama.2025.2726)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

A Digital Depression Treatment Program for Adults Treated in Primary Care

Posted April 10, 2025 by Jim Michalski

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Prevalence of Motor Milestone Delays in Autistic Children

Posted April 10, 2025 by Jim Michalski

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Patterns in Nonfatal Self-Harm Among Adolescents

Posted April 10, 2025 by Jim Michalski

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Adolescent Disparities in Exposure to Adverse Childhood Experiences by Gender Identity

Posted April 10, 2025 by Jim Michalski

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Incidence of Pancreas and Colorectal Adenocarcinoma in the US

Posted April 10, 2025 by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, MONDAY, APRIL 14, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.4682?guestAccessKey=c0957767-f5eb-4d6d-88a4-15c747418b57&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=041425

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: The findings of this cohort study suggest that the incidence of pancreatic adenocarcinoma has increased among all age groups, whereas that of colorectal adenocarcinoma has increased among younger age groups. Clinicians should be aware of this trend when evaluating younger patients with relevant symptoms.

Corresponding Author: To contact the corresponding author, Arvind J. Trindade, MD, email arvind.trindade@gmail.com.

(doi:10.1001/jamanetworkopen.2025.4682)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Gestational Age and Cognitive Development in Childhood

Posted April 10, 2025 by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, MONDAY, APRIL 14, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.4580?guestAccessKey=c0957767-f5eb-4d6d-88a4-15c747418b57&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=041425

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: In this cross-sectional study of children ages 9 to 10, moderately preterm birth was associated with long-term cognitive problems independent of socioeconomic status, genetics, and other risk factors. These findings underscore the need for continued follow-up of all preterm children, with particular focus on those born before 34 weeks’ gestational age, because they may face greater developmental challenges over time.

Corresponding Author: To contact the corresponding author, Samson Nivins, PhD, email samson.nivins@ki.se.

(doi:10.1001/jamanetworkopen.2025.4580)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Projected Lifetime Cancer Risks From Current Computed Tomography Imaging

Posted April 10, 2025 by Jim Michalski

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, APRIL 14, 2025

Media advisory: The full study and editor’s note are linked to this news release.

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https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/10.1001/jamainternmed.2025.0505?guestAccessKey=afde7c2e-df6b-4e7b-9ced-7a15ed74dc1d&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=041425

About The Study: This study found that at current utilization and radiation dose levels, computed tomography examinations in 2023 were projected to result in approximately 103,000 future cancers over the course of the lifetime of exposed patients. If current practices persist, computed tomography-associated cancer could eventually account for 5% of all new cancer diagnoses annually.

Corresponding Author: To contact the corresponding author, Rebecca Smith-Bindman, MD, email rebecca.smith-bindman@ucsf.edu.

(doi:10.1001/jamainternmed.2025.0505)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Use of Life Support and Outcomes Among Patients Admitted to Intensive Care Units

Posted April 9, 2025 by Jim Michalski

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Drug Decriminalization in British Columbia and Changes in Drug Crime and Opioid and Stimulant Harms

Posted April 9, 2025 by Jim Michalski

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Interventions for Childhood Central Obesity

Posted April 9, 2025 by Jim Michalski

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Responses to the Gaza-Israel Conflict by Specialty Medical Societies

Posted April 9, 2025 by Jim Michalski

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Risk Factors for Severe Disease Among Children Hospitalized With RSV

Posted April 9, 2025 by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, APRIL 11, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.4666?guestAccessKey=c0957767-f5eb-4d6d-88a4-15c747418b57&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=041125

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: In this cohort study of children hospitalized with respiratory syncytial virus (RSV) in 2022 and 2023, severe RSV disease was more likely among those age 2 or older with pulmonary and neurologic, neuromuscular, or developmental conditions. For children younger than 2 years, age younger than 6 months and prematurity were the main risk factors. These findings support prevention strategies for all younger children, including premature infants, with potential benefit for children age 2 or older in specific high-risk groups.

Corresponding Author: To contact the corresponding author, Peter J. Gill, MD, DPhil, MSc, email peter.gill@sickkids.ca.

(doi:10.1001/jamanetworkopen.2025.4666)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

# # #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Kidney Function Following COVID-19 in Children and Adolescents

Posted April 9, 2025 by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, APRIL 11, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.4129?guestAccessKey=c0957767-f5eb-4d6d-88a4-15c747418b57&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=041125

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: In this large U.S. cohort study of children and adolescents, SARS-CoV-2 infection was associated with a higher risk of adverse postacute kidney outcomes, particularly among those with preexisting chronic kidney disease or acute kidney injury, suggesting the need for vigilant long-term monitoring.

Corresponding Author: To contact the corresponding author, Yong Chen, PhD, email ychen123@pennmedicine.upenn.edu.

(doi:10.1001/jamanetworkopen.2025.4129)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

# # #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Olfactory Deficits and Mortality in Older Adults

Posted April 8, 2025 by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time

https://jamanetwork.com/journals/jamaotolaryngology/fullarticle/10.1001/jamaoto.2025.0174?guestAccessKey=20413ea8-47ec-4b7e-96af-9f18cc7855af&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=041025

Childcare Barriers and Appointment Nonadherence Among Women in a Safety-Net Health System

Posted April 8, 2025 by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.4715?guestAccessKey=3158245a-281f-4483-9915-f2f34cb4fbf7&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=041025

Stigma Experiences of Sexual and Gender Minority Parents and Offspring Mental Health

Posted April 8, 2025 by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.4502?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=041025

Neighborhood Characteristics and Mental Health From Childhood to Adolescence

Posted April 8, 2025 by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, APRIL 10, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.4470?guestAccessKey=c0957767-f5eb-4d6d-88a4-15c747418b57&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=041025

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: In this cohort study of children and adolescents, associations between neighborhood characteristics and mental health evolved from childhood through adolescence. These findings suggest that targeted interventions in disadvantaged neighborhoods and strategies to protect young children from air pollution are essential. A comprehensive approach is recommended to incorporate air pollution, green space, and socioeconomic status not only in residential neighborhoods but also in other settings, such as schools.

Corresponding Author: To contact the corresponding author, Niloofar Shoari, PhD, email n.shoari@ucl.ac.uk.

(doi:10.1001/jamanetworkopen.2025.4470)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

# # #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.