Variability in Primary Care Telehealth Delivery Methods Across Chronic Conditions

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Older Adults’ Views on Insurance Coverage for Weight Management Medications

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, MARCH 26, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this survey study of older U.S. adults, most participants agreed that Medicare should cover weight management medications and more than half of those with body mass index (BMI) of 30 or greater were interested in using them. These results should inform decisions to include weight management medications in the Medicare and commercial insurance programs, as well as utilization policies to control health care costs.

Corresponding Author: To contact the corresponding author, Lauren Oshman, MD, MPH, email laoshman@umich.edu.

 

(doi:10.1001/jamanetworkopen.2025.2008)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Suicide Risk and Living Alone With Depression or Anxiety

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, MARCH 26, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this cohort study of 3.7 million individuals, living alone with depression or anxiety was associated with an increased risk of suicide, particularly among middle-aged individuals and men. These findings underscore the importance of preventing mental illness, such as depression and anxiety, while addressing living arrangements as a critical factor in suicide risk assessments for individuals with these conditions.

Corresponding Authors: To contact the corresponding authors, email Hong Jin Jeon, MD, PhD (jhj001001@gmail.com) and Kyungdo Han, PhD (hkd917@naver.com).

 

(doi:10.1001/jamanetworkopen.2025.1227)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Risk Factors for Health Care–Associated Bloodstream Infections in NICUs

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Patient Complexity and Bile Duct Injury After Robotic-Assisted vs Laparoscopic Cholecystectomy

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US Population Size and Outcomes of Adults on Liver Transplant Waiting Lists

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LGBTQ+ Inclusive Policies, Nurse Job Outcomes, and Quality of Care in Hospitals

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, TUESDAY, MARCH 25, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: Nurses in hospitals with high lesbian, gay, bisexual, transgender, queer or questioning, and other sexual and gender minority (LGBTQ+) inclusion reported more favorable job outcomes and care quality in this cross-sectional study. Hospitals should understand that implementing LGBTQ+ inclusive policies goes beyond compliance or diversity; it is essential for improving the work climate, enhancing staff well-being, and optimizing care delivery.

Corresponding Author: To contact the corresponding author, Hyunmin Yu, PhD, email hyuy@nursing.upenn.edu.

 

(doi:10.1001/jamanetworkopen.2025.1765)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Recovery Potential in Patients After Cardiac Arrest Who Die After Limitations or Withdrawal of Life Support

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, TUESDAY, MARCH 25, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this cohort study of comatose patients resuscitated from cardiac arrest, most who died after withdrawal of life-sustaining therapy were considered by experts to have had recovery potential. These findings suggest that novel solutions to avoiding deaths based on biased prognostication or incomplete information are needed.

Corresponding Author: To contact the corresponding author, Jonathan Elmer, MD, MS, email elmerjp@upmc.edu.

 

(doi:10.1001/jamanetworkopen.2025.1714)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Long-Term Risk of Stroke After Transient Ischemic Attack or Minor Stroke

JAMA

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, MARCH 26, 2025

Media advisory: The full study is linked to this news release.

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About The Study: Patients who have had a transient ischemic attack (TIA) or minor stroke are at a persistently high risk of subsequent stroke. The findings from this study underscore the need for improving long-term stroke prevention measures in this patient group. 

Corresponding Author: To contact the corresponding author, Faizan Khan, PhD, email faizan.khan1@ucalgary.ca.

 

(doi:10.1001/jama.2025.2033)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Kidney Transplant Wait Times Under Waiting List Expansion Scenarios

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Breastfeeding Duration and Child Development

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, MONDAY, MARCH 24, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: Exclusive or longer duration of breastfeeding was associated with reduced odds of developmental delays and language or social neurodevelopmental conditions in this cohort study. These findings may guide parents, caregivers, and public health initiatives in promoting early child development.

Corresponding Author: To contact the corresponding author, Inbal Goldshtein, PhD, email inbal@kinstitute.org.il.

 

(doi:10.1001/jamanetworkopen.2025.1540)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Age-Specific Trends in Pediatric and Adult Firearm Homicide After the Onset of the COVID-19 Pandemic

JAMA Pediatrics

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, MARCH 24, 2025

Media advisory: The full study is linked to this news release.

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About The Study: This study found a disproportionate spike in firearm homicide among children and adults older than age 30 after the onset of the COVID-19 pandemic, indicating a change in the association between age and firearm victimization risk. This trend moved the peak victimization risk from age 21 to 19, and rates for children up to age 16 were markedly elevated. These age-specific patterns were most pronounced in later post-onset years. 

Corresponding Author: To contact the corresponding author, Jonathan Jay, DrPH, JD, email jonjay@bu.edu.

 

(doi:10.1001/jamapediatrics.2025.0136)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Avoidable Mortality Across US States and High-Income Countries

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, MARCH 24, 2025

Media advisory: The full study is linked to this news release.  

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About The Study: This study found that avoidable mortality (comprising both preventable deaths related to prevention and public health and treatable deaths related to timely and effective health care treatment) has worsened across all U.S. states, while other high-income countries show improvement. The results suggest poorer mortality is driven by broad factors across the entirety of the U.S. While other countries appear to make gains in health with increases in health care spending, such an association does not exist across U.S. states, raising questions regarding U.S. health spending efficiency. 

Corresponding Author: To contact the corresponding author, Irene Papanicolas, PhD, email irene_papanicolas@brown.edu.

 

(doi:10.1001/jamainternmed.2025.0155)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Presymptomatic Awareness of BRCA1/BRCA2 Status and Outcomes In Women With Ovarian Cancer

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Medicaid Eligibility Gaps and Pandemic-Era Postpartum Insurance Rates

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About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

Safer Opioid Supply, Subsequent Drug Decriminalization, and Opioid Overdoses

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About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

State Earned Income Tax Credits and Firearm Suicides

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, MARCH 21, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this cohort study, the presence and generosity of state refundable earned income tax credits were associated with a decrease in firearm suicide rates, supporting the growing body of literature highlighting the importance of antipoverty policies for reducing firearm suicide.

Corresponding Author: To contact the corresponding author, Nicole Asa, MPH, email nasa3@uw.edu.

 

(doi:10.1001/jamanetworkopen.2025.1398)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Racial and Ethnic Inequalities in Actual vs Nearest Delivery Hospitals

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, MARCH 21, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: This cohort study found that American Indian and Black individuals delivered at lower-quality hospitals than white individuals. The disparity in care between Black and white birthing individuals would have been reduced if individuals had delivered at their nearest hospital.

Corresponding Author: To contact the corresponding author, Nansi S. Boghossian, PhD, email nboghoss@email.sc.edu.

 

(doi:10.1001/jamanetworkopen.2025.1404)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Accelerated Aging in Survivors of Childhood Cancer—Early Onset and Excess Risk of Chronic Conditions

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USPSTF Lung Cancer Screening Guidelines and Disparities in Screening Adherence

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Racial and Ethnic Disparities in EMS Use of Restraints and Sedation for Patients With Behavioral Health Emergencies

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Cancer Antigen 125 Levels at Time of Ovarian Cancer Diagnosis by Race and Ethnicity

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, MARCH 20, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this cohort study of patients with ovarian cancer, American Indian and Black patients were 23% less likely to have an elevated cancer antigen (CA)-125 level at diagnosis. Current CA-125 thresholds may miss racially and ethnically diverse patients with ovarian cancer. International guidelines use CA-125 thresholds to recommend which patients with pelvic masses should undergo evaluation by gynecologic oncologists for ovarian cancer. However, CA-125 thresholds were developed from white populations. Work is needed to develop inclusive CA-125 thresholds and diagnostic guidelines and not compound disparities in ovarian cancer diagnosis and treatment.

Corresponding Author: To contact the corresponding author, Anna Jo Bodurtha Smith, MD, MPH, email annajo.smith@pennmedicine.upenn.edu.

 

(doi:10.1001/jamanetworkopen.2025.1292)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Prevalence and Severity of Astigmatism in Children After COVID-19

JAMA Ophthalmology

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, MARCH 20, 2025

Media advisory: The full study and commentary are linked to this news release.

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About The Study: In this study, lifestyle changes after the pandemic were associated with an increase in the prevalence and severity of child astigmatisms, likely associated with changes in the developing cornea. The potential impact of higher degrees of astigmatism may warrant dedicated efforts to elucidate the relationship between environmental and/or lifestyle factors, as well as the pathophysiology of astigmatism.

Corresponding Authors: To contact the corresponding authors, email Jason C. Yam, MD (yamcheuksing@cuhk.edu.hk) and Li Jia Chen, PhD (lijia_chen@cuhk.edu.hk).

 

(doi:10.1001/jamaophthalmol.2025.0205)

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Law Enforcement Drug Seizures and Opioid-Involved Overdose Mortality

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Fertility of Adults Born Very Preterm or With Very Low Birth Weight

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Prescription Stimulant Use, Misuse, and Use Disorder Among US Adults Ages 18 to 64

JAMA Psychiatry

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, MARCH 19, 2025

Media advisory: The full study is linked to this news release.

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About The Study: Although access to prescription stimulants is essential to addressing important clinical needs of patients with attention-deficit/hyperactivity disorder (ADHD), this study found that among U.S. adults ages 18 to 64 using prescription stimulants, one-fourth reported misuse, and nearly one-tenth had prescription stimulant use disorder. The findings may suggest potential progress in addressing the mental health care gap for middle-aged women and the need for evidence-based clinical guidance and training on benefits and risks of prescription stimulants for adults. 

Corresponding Author: To contact the corresponding author, Wilson M. Compton, MD, MPE, email wcompton@nida.nih.gov.

 

(10.1001/jamapsychiatry.2025.0054)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Suicide and Self-Harm Events With GLP-1 Receptor Agonists in Adults With Diabetes or Obesity

JAMA Psychiatry

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, MARCH 19, 2025

Media advisory: The full study is linked to this news release.

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About The Study: There is unlikely to be an increase in the very low incidence of suicide-related adverse events among individuals receiving glucagon-like peptide 1 receptor agonists (GLP-1 RAs) within the context of randomized clinical trials. While these findings may further ease concerns about these adverse effects, continued monitoring is warranted to identify particular patients who may be at risk as extended use of GLP-1 RAs expands. 

Corresponding Author: To contact the corresponding author, Sean P. Heffron, MD, MS, MSc, email sean.heffron@nyulangone.org.

 

(10.1001/jamapsychiatry.2025.0091)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Mailed Outreach and Patient Navigation for Colorectal Cancer Screening Among Rural Medicaid Enrollees

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Adherence to Annual Lung Cancer Screening and Rates of Cancer Diagnosis

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, MARCH 18, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: In this multicenter cohort study of adults undergoing lung cancer screening, screening adherence was associated with increased overall and early-stage lung cancer detection rates; however, adherence decreased annually after baseline screening, suggesting that it is an important lung cancer screening quality metric.

Corresponding author: To contact the corresponding author, Roger Y. Kim, M.D., M.S.C.E., email roger.kim@pennmedicine.upenn.edu.

 

(doi: 10.1001/jamanetworkopen.2025.0942)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Geographic Access to Cancer Care and Treatment and Outcomes of Early-Stage Non–Small Cell Lung Cancer

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, MARCH 18, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: In this cohort study, geographic access to cancer care was associated with guideline-recommended treatment for early-stage non–small cell lung cancer (NSCLC) and outcomes, particularly in socially marginalized patients, underscoring the importance of ensuring appropriate geographic allocations of cancer care resources and addressing travel barriers to health care to improve NSCLC treatment, prognosis, and equity.

Corresponding authors: To contact the corresponding authors, email Ying Liu, MD, PhD (yliu3@wustl.edu) and Min Lian, MD, PhD (lian200@wustl.edu).

 

(doi: 10.1001/jamanetworkopen.2025.1061)

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Health Care Contact Days, Care Experience, and Out-of-Pocket Spending Among Traditional Medicare Patients

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Racial Equity in Urine Drug Screening Policies in Labor and Delivery

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Gender-Affirming Hormone Therapy and Depressive Symptoms Among Transgender Adults

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, MONDAY, MARCH 17, 2025

Media advisory: The full study and commentary are linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this longitudinal observational cohort study, gender-affirming hormone therapy was associated with lower rates of moderate-to-severe depressive symptoms, highlighting the importance of gender-affirming primary care models for transgender, nonbinary, and gender diverse patients.

Corresponding Author: To contact the corresponding author, Sari L. Reisner, ScD, MA, email sreisner@umich.edu.

 

(doi:10.1001/jamanetworkopen.2025.0955)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Statin Use and Risk of Hepatocellular Carcinoma and Liver Fibrosis in Chronic Liver Disease

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, MARCH 17, 2025

Media advisory: The full study is linked to this news release.  

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About The Study: This cohort study found that statin use was associated with a reduced risk of hepatocellular carcinoma and hepatic decompensation in patients with chronic liver disease. These findings provide support for the potential role of statins in prevention of hepatocellular carcinoma and liver disease progression. 

Corresponding Authors: To contact the corresponding authors, email Jonggi Choi, MD, PhD, (j.choi@amc.seoul.kr) and Raymond T. Chung, MD, (chung.raymond@mgh.harvard.edu).

 

(doi:10.1001/jamainternmed.2025.0115)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Probiotics and Fever Duration in Children With Upper Respiratory Tract Infections

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Telephone Counseling and Messaging Guided by Mobile Profiling of Tobacco Users for Smoking Cessation

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Health Concerns of Youths From Historically Marginalized Communities During the Postacute Phase of COVID-19

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Lifetime and Past-Year Defensive Gun Use

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, MARCH 14, 2025

Media advisory: The full study and commentary are linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this survey of adults with firearm access, defensive gun use (DGU) was rare relative to gun violence exposure. Perceived threats may not necessitate DGU, and given the association between DGU and gun violence exposure, the consequences of DGU may be substantial. Narratives centering DGU as a consideration in firearm policies may misstate the risk profile of firearm access.

Corresponding Author: To contact the corresponding author, Michael D. Anestis, PhD, email mda141@sph.rutgers.edu.

 

(doi:10.1001/jamanetworkopen.2025.0807)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Lifetime Health Effects and Cost-Effectiveness of Tirzepatide and Semaglutide in US Adults

JAMA Health Forum

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, MARCH 14, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

 

About The Study: This economic evaluation found that although tirzepatide and semaglutide offered substantial long-term health benefits, they were not cost-effective at current net prices. Efforts to reduce the net prices of new anti-obesity medications are essential to ensure equitable access to highly effective anti-obesity medications.

Corresponding Author: To contact the corresponding author, Jennifer H. Hwang, DO, email jennifer.hwang2@bsd.uchicago.edu.

 

(doi:10.1001/jamahealthforum.2024.5586)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Area Socioeconomic Status, Vaccination Access, and Female HPV Vaccination

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, MARCH 13, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this cross-sectional study of area deprivation, vaccination access, and human papillomavirus (HPV) vaccination status in Osaka City, Japan, higher socioeconomic status and higher medical facility access were associated with higher cumulative HPV vaccination uptake. These findings suggest that further strategies, including a socioecologic approach, are needed to increase HPV vaccination and reduce disparities in uptake.

Corresponding Author: To contact the corresponding author, Yuri Ito, PhD, email yuri.ito@ompu.ac.jp.

 

(doi:10.1001/jamanetworkopen.2025.0747)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Prenatal Depression and Symptom Severity by Maternal Race and Ethnicity

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High Sugar-Sweetened Beverage Intake and Oral Cavity Cancer in Smoking and Nonsmoking Women

JAMA Otolaryngology–Head & Neck Surgery

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, MARCH 13, 2025

Media advisory: The full study is linked to this news release.

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About The Study: High sugar-sweetened beverage intake was associated with a significantly increased risk of oral cavity cancer in women, regardless of smoking or drinking habits, yet with low baseline risk in this study. Additional studies are needed in larger cohorts, including males, to validate the impact of these findings.

Corresponding Author: To contact the corresponding author, Brittany Barber, MD, MSc, email bbarber1@uw.edu.

 

(doi:10.1001/jamaoto.2024.5252)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Estimated Cancer Risk in Females Who Meet the Criteria to Exit Cervical Cancer Screening

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Exercise and Psychosexual Education to Improve Sexual Function in Men With Prostate Cancer

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Nicotine Exposure From Smoking Tobacco and Vaping Among Adolescents

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Lipid Profiles After Changes in Alcohol Consumption Among Adults Undergoing Annual Checkups

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Association of Diet and Waist-to-Hip Ratio With Brain Connectivity and Memory in Aging

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, MARCH 12, 2025

Media advisory: The full study and commentary are linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: This cohort study found that healthier diets and lower waist to hip ratio throughout midlife were associated with better brain and cognitive health in older age. The findings suggest that interventions to improve diet and manage central obesity might be most effective between ages 48 and 70.

Corresponding Author: To contact the corresponding author, Daria E. A. Jensen, DPhil, email jensen@cbs.mpg.de.

 

(doi:10.1001/jamanetworkopen.2025.0171)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Food Insecurity and Incident Cardiovascular Disease Among Black and White US Individuals

JAMA Cardiology

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, MARCH 12, 2025

Media advisory: The full study is linked to this news release.

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About The Study: In this prospective cohort study among participants in the Coronary Artery Risk Development in Young Adults (CARDIA) study, food insecurity was associated with incident cardiovascular disease (CVD) even after adjustment for socioeconomic factors, suggesting that food insecurity may be an important social deprivation measure in clinical assessment of CVD risk. Whether interventions to reduce food insecurity programs can potentially alleviate CVD should be further studied. 

Corresponding Author: To contact the corresponding author, Jenny Jia, MD, MSc, email jenny.jia@northwestern.edu.

 

(doi:10.1001/jamacardio.2025.0109)

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Sex Differences in Apolipoprotein E and Alzheimer Disease Pathology Across Ancestries

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Electronic Health Record Use During Paid Time Off Among Primary Care Physicians

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Ethics in Patient Preferences for AI–Drafted Responses to Electronic Messages

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, TUESDAY, MARCH 11, 2025

Media advisory: The full study and commentary are linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this survey study, participants expressed a mild preference for messages written by artificial intelligence (AI) but had a slightly decreased satisfaction when told AI was involved. Patient experience must be considered along with ethical implementation of AI. Although AI disclosure may slightly reduce satisfaction, disclosure should be maintained to uphold patient autonomy and empowerment.

Corresponding Author: To contact the corresponding author, Anand Chowdhury, MD, MMCi, email anand.chowdhury@duke.edu.

 

(doi:10.1001/jamanetworkopen.2025.0449)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Cardiovascular Health and Biomarkers of Neurodegenerative Disease in Older Adults

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, TUESDAY, MARCH 11, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: The findings of this study suggest that promoting cardiovascular health in older adults may help alleviate the burden of neurodegenerative diseases, particularly among Black adults, who are known to experience a higher prevalence of cardiovascular disease.

Corresponding Author: To contact the corresponding author, Anisa Dhana, MD, MSc, email anisa_dhana@rush.edu.

 

(doi:10.1001/jamanetworkopen.2025.0527)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Sexual Orientation– and Gender Identity–Affirming Activities Provided in Primary Care

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Long-Term Effects of a Responsive Parenting Intervention on Child Weight Outcomes Through Age 9

JAMA Pediatrics

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, MARCH 10, 2025

Media advisory: The full study is linked to this news release.

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About The Study: An early-life responsive parenting intervention resulted in lower body mass index from age 3 to 9 compared with a control intervention. This group difference was driven by effects on female participants, with differences appearing to dissipate over time. A life-course approach may be required to sustain the benefits of early-life responsive parenting interventions for obesity prevention. 

Corresponding Author: To contact the corresponding author, Ian M. Paul, MD, MSc, email ipaul@psu.edu.

 

(doi:10.1001/jamapediatrics.2024.6897)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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COVID-19 Pandemic and the Developmental Health of Kindergarteners

JAMA Pediatrics

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, MARCH 10, 2025

Media advisory: The full study is linked to this news release.

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About The Study: The COVID-19 pandemic was associated with varying developmental health outcomes in kindergarteners. Negative developmental trends existed immediately before the pandemic, with most persisting or slowing post-pandemic onset. These results highlight troubling trends in kindergarteners’ development, both before and during the pandemic, and more information is needed to understand why developmental outcomes are worsening over time.

Corresponding Author: To contact the corresponding author, Judith L. Perrigo, PhD, LCSW, email jperrigo@luskin.ucla.edu.

 

(doi:10.1001/jamapediatrics.2024.7057)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Post-Dobbs Decision Changes in Obstetrics and Gynecology Clinical Workforce in States With Abortion Restrictions

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, MARCH 10, 2025

Media advisory: The full study is linked to this news release.  

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About The Study: While practitioner supply increased overall, the Dobbs decision was associated with moderate but significant relative decreases in obstetrics and gynecology practitioners in the most restrictive vs control states. Findings provide early confirmation of reports that clinicians have migrated from states most impacted by the Dobbs decision. Clinician migration has implications for reproductive care access, quality, and equity as abortion rights are increasingly decided at the state level. 

Corresponding Author: To contact the corresponding author, Jane M. Zhu, MD, MPP, email zhujan@ohsu.edu.

 

(doi:10.1001/jamainternmed.2024.8149)

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Enhanced COVID-19 Provider Relief, Hospital Finances, and Care for Medicare Inpatients

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama-health-forum/fullarticle/10.1001/jamahealthforum.2025.0046?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=030725

About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

USPSTF Statement on Screening for Food Insecurity

JAMA

EMBARGOED FOR RELEASE: 10:30 A.M. (ET), TUESDAY, MARCH 11, 2025

Media advisory: To contact the U.S. Preventive Services Task Force, email the Media Coordinator at Newsroom@USPSTF.net or call 301-951-9203. The full report and related articles are linked to this news release.

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Bottom Line: The U.S. Preventive Services Task Force (USPSTF) concludes that the current evidence is insufficient to assess the balance of benefits and harms of screening for food insecurity on health outcomes in the primary care setting. According to survey data, 12.8% of households experienced food insecurity in 2022, with 7.7% of households experiencing low food security and 5.1% experiencing very low food security. Nearly one-third of households with incomes below the federal poverty threshold are food insecure. Food insecurity is one among a multitude of medical, psychological, and social conditions common among economically disadvantaged households. The USPSTF routinely makes recommendations about the effectiveness of preventive care services. This is a new USPSTF topic.

 

(doi:10.1001/jama.2025.0879)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.

Note: More information about the U.S. Preventive Services Task Force, its process, and its recommendations can be found on the newsroom page of its website.

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Direct Exposure to Mass Shootings Among US Adults

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, MARCH 7, 2025

Media advisory: The full study and commentary are linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: The findings from this survey study of U.S. adults underscore the extensive and often overlooked regular exposure to mass shootings in this country. The demographic disparities in exposure highlight the need for targeted interventions and support for the most affected groups, particularly younger generations and males. Understanding these patterns is essential for addressing the broader impacts of gun violence on public health and community well-being.

Corresponding Author: To contact the corresponding author, David C. Pyrooz, PhD, email david.pyrooz@colorado.edu.

 

(doi:10.1001/jamanetworkopen.2025.0283)

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Prevalence of Depression and Anxiety Among Adults With Chronic Pain

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, MARCH 7, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this systematic review and meta-analysis of depression and anxiety among individuals with chronic pain, approximately 40% of adults had clinically significant depression and anxiety. Women, younger people, and people with nociplastic pain were most likely to have depression and anxiety. The co-occurrence of chronic pain with depression and anxiety is a significant public health concern necessitating routine screening in clinical settings, equitable access to specialty care, and innovative treatment development.

Corresponding Author: To contact the corresponding author, Rachel V. Aaron, PhD, email raaron4@jhmi.edu.

 

(doi:10.1001/jamanetworkopen.2025.0268)

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Butter and Plant-Based Oils Intake and Mortality

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 4 P.M. (ET), THURSDAY, MARCH 6, 2025

Media advisory: The full study and commentary are linked to this news release. This study is being presented at the American Heart Association EPI/Lifestyle Scientific Sessions 2025. 

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About The Study: Higher intake of butter was associated with increased mortality, while higher plant-based oils intake was associated with lower mortality in this cohort study. Substituting butter with plant-based oils may confer substantial benefits for preventing premature deaths. 

Corresponding Author: To contact the corresponding author, Dong D. Wang, MD, ScD, email dow471@mail.harvard.edu.

 

(doi:10.1001/jamainternmed.2025.0205)

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Intentional Weight Loss, Waist Circumference Reduction, and Mortality Risk Among Postmenopausal Women

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, MARCH 6, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: Reported intentional weight loss efforts that were coupled with measured waist circumference reductions were associated with lower risk of all-cause, cancer, and cardiovascular mortality in this cohort study. Attention to diet and exercise that promote reductions in central adiposity should be encouraged.

Corresponding Author: To contact the corresponding author, Michael Hendryx, PhD, email hendryx@iu.edu.

 

(doi:10.1001/jamanetworkopen.2025.0609)

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HIV Viral Suppression With Use of Long-Acting Antiretroviral Therapy in People With and Without Initial Viremia

JAMA

EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, MARCH 6, 2025

Media advisory: The full study is linked to this news release.

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https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2025.0109?guestAccessKey=9eb2113f-9352-4f92-a12c-dfea7aa1522d&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=030625

 

About The Study: In a program using long-acting-antiretroviral therapy (LA-ART) for people with HIV, this study found that viral suppression with use of LA-ART at 48 weeks was high and did not differ among individuals starting LA-ART with or without viremia. The low CD4+ cell counts among those with viremia confirms this population was at high risk of continued disease progression. 

Corresponding Author: To contact the corresponding author, Monica Gandhi, MD, MPH, email monica.gandhi@ucsf.edu.

 

(doi:10.1001/jama.2025.0109)

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Hematologic Cancers Among Patients With Type 2 Diabetes Prescribed GLP-1 Receptor Agonists

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, MARCH 6, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: The findings of this cohort study suggest that glucagon-like peptide–1 receptor agonists (GLP-1RAs) are associated with reduced risk of developing several hematologic cancers, particularly myelodysplastic syndrome and myeloproliferative neoplasm, in patients with type 2 diabetes. This reduction in risk may be mediated by weight loss, the immunomodulatory properties of GLP-1RAs, or both.

Corresponding Author: To contact the corresponding author, Abhay Singh, MD, MPH, email singha21@ccf.org.

 

(doi:10.1001/jamanetworkopen.2025.0802)

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Sleep Characteristics and Long-Term Risk of Type 2 Diabetes Among Women With Gestational Diabetes

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Trajectories of Sleep Duration, Sleep Onset Timing, and Continuous Glucose Monitoring in Adults

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, MARCH 5, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this cohort study of middle-aged and older participants, persistent inadequate sleep duration and late sleep onset, whether alone or in combination, were associated with greater glycemic variability. These findings emphasize the importance of considering both sleep duration and timing for optimizing glycemic control in the general population.

Corresponding Authors: To contact the corresponding authors, email Ju-Sheng Zheng, PhD, (zhengjusheng@westlake.edu.cn) and Yu-ming Chen, PhD, (chenyum@mail.sysu.edu.cn).

 

(doi:10.1001/jamanetworkopen.2025.0114)

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Sports Gambling and Drinking Behaviors Over Time

JAMA Psychiatry

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, MARCH 5, 2025

Media advisory: The full study is linked to this news release.

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About The Study: This study found that over time, the trajectory of sports gambling frequency was associated with the trajectory of alcohol-related problems. Screening and treatment interventions are recommended for sport gamblers who also drink concurrently, especially because this group appears to be at an elevated risk for developing greater alcohol-related problems over time. 

Corresponding Author: To contact the corresponding author, Joshua B. Grubbs, PhD, email joshuagrubbs12@unm.edu

 

(10.1001/jamapsychiatry.2025.0024)

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Cancer Screening 3 Years After the Onset of the COVID-19 Pandemic

JAMA

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, MARCH 5, 2025

Media advisory: The full study is linked to this news release.

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About The Study: In 2023, reported breast and colorectal cancer screening rebounded from COVID-19 pandemic–related declines and surpassed pre-pandemic estimates. These findings are encouraging given larger-than-expected declines in early-stage breast and colorectal cancer diagnoses in 2020 and increases in distant-stage breast cancer diagnoses through 2021. Cervical cancer screening rates remained below pre-pandemic levels, a troubling trend as early-stage diagnoses continued to decrease in 2021. The persistent decline may in part reflect longer-term declines in patient knowledge and clinician recommendation of cervical cancer screening.

Corresponding Author: To contact the corresponding author, Jessica Star, MA, MPH, email Jessica.star@cancer.org.

 

(doi:10.1001/jama.2025.0902)

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Effects of Combining Coronary Calcium Score With Treatment on Plaque Progression in Familial Coronary Artery Disease

JAMA

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, MARCH 5, 2025

Media advisory: The full study and related articles are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2025.0584?guestAccessKey=df760f19-4a36-437b-adc9-753e8dac66b9&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_cotent=tfl&utm_term=030525

 

About The Study: The combination of coronary artery calcium (CAC) score with a primary prevention strategy in intermediate-risk patients with a family history of coronary artery disease was associated with reduction of atherogenic lipids and slower plaque progression compared with usual care. These data support the use of CAC score to assist intensive preventive strategies in intermediate-risk patients.

Corresponding Author: To contact the corresponding author, Thomas H. Marwick, MBBS, PhD, MPH, email Tom.Marwick@bakeridi.edu.au.

 

(doi:10.1001/jama.2025.0584)

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Postoperative Aspiration Pneumonia Among Adults Using GLP-1 Receptor Agonists

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, MARCH 4, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: This cohort study found no significant association between the preoperative use of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and short-term postoperative aspiration pneumonia despite growing concerns about the adverse effects of these medications after surgery. This finding suggests that it may be beneficial to reassess the preoperative withholding guidelines for GLP-1 RAs.

Corresponding author: To contact the corresponding author, Eric L. Smith, M.D., email esmith@nebh.org.

 

(doi: 10.1001/jamanetworkopen.2025.0081)

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Perceived Discrimination in Health Care Settings and Care Delays in Patients With Diabetes and Hypertension

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, MARCH 4, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: The findings of this study suggest that higher perceived discrimination in health care settings is positively associated with delaying health care due to nervousness about seeing a health care professional. The largest mediation proportion observed was among younger adults and racial and ethnic minority groups. By prioritizing better patient-clinician communication, health care delays associated with patient apprehension related to perceived discrimination may be reduced.

Corresponding author: To contact the corresponding author, Maryam Jafari Bidgoli, Ph.D., email mjafaribidgoli@ua.edu.

 

(doi: 10.1001/jamanetworkopen.2025.0046)

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