Medical Debt and Forgone Mental Health Care Due to Cost Among Adults

JAMA Health Forum

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, APRIL 18, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

 

About The Study: In this survey study, more than 1 in 7 adults reported carrying medical debt in 2023, of whom 1 in 3 forwent mental health care in the subsequent year. Medical debt may exacerbate the treatment gap by potentially (1) raising the threshold for seeking care, (2) eroding patient trust in the health system, or (3) being denied care due to outstanding debts.

Corresponding Author: To contact the corresponding author, Catherine K. Ettman, PhD, email cettman1@jh.edu.

 

(doi:10.1001/jamahealthforum.2025.0383)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Legalizing Youth-Friendly Cannabis Edibles and Extracts and Adolescent Cannabis Use

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, APRIL 18, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this serial cross-sectional study of adolescents in grades 7 to 11, legalization of cannabis edibles and extracts was associated with an increase not only in edible cannabis use and cannabis smoking, but also in the overall prevalence of cannabis use and co-use of alcohol and cannabis, highlighting the need for stricter policy measures to curb adolescents’ access to cannabis edibles and extracts and greater awareness among adolescents about harms of cannabis use.

Corresponding Author: To contact the corresponding author, Hai V. Nguyen, PhD, email hvnguyen@mun.ca.

 

(doi:10.1001/jamanetworkopen.2025.5819)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Health-Related Quality of Life in the US Territories of Puerto Rico, Guam, and the Virgin Islands

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Population Attributable Fraction of Incident Dementia Associated With Hearing Loss

JAMA Otolaryngology–Head & Neck Surgery

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, APRIL 17, 2025

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About The Study: The results of this cohort study suggest that treating hearing loss might delay dementia for a large number of older adults. Public health interventions targeting clinically significant audiometric hearing loss might have broad benefits for dementia prevention. Future research quantifying population attributable fractions should carefully consider which measures are used to define hearing loss, as self-reporting may underestimate hearing-associated dementia risk.

Corresponding Author: To contact the corresponding author, Jason R. Smith, ScM, email jsmit491@jhu.edu.

 

(doi:10.1001/jamaoto.2024.0192)

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Prevalence of Obesity With and Without Confirmation of Excess Adiposity Among US Adults

JAMA

EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, APRIL 17, 2025

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About The Study: Among U.S. adults ages 20 to 59, the prevalence of obesity by body mass index (BMI) only was nearly identical with the obesity prevalence after confirmation of excess adiposity. Approximately 98% of individuals identified as having obesity based on BMI had excess adiposity.

Corresponding Author: To contact the corresponding author, Michael Fang, PhD, MHS, email mfang9@jh.edu.

 

(doi:10.1001/jama.2025.2704)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Digital Photography Guide for Dermatologists With Special Considerations for Diverse Populations

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Preferences for Communication About Prognosis Among Children With Cancer, Parents, and Oncologists

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AI–Enabled Prediction of Heart Failure Risk From Single-Lead Electrocardiograms

JAMA Cardiology

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, APRIL 16, 2025

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About The Study: Across multinational cohorts, a noise-adapted artificial intelligence (AI)-electrocardiogram (ECG) model estimated heart failure risk using lead I ECGs, suggesting a potential heart failure risk-stratification strategy requiring prospective study using wearable and portable ECG devices.

Corresponding Author: To contact the corresponding author, Rohan Khera, MD, MS, email rohan.khera@yale.edu.

 

(doi:10.1001/jamacardio.2025.0492)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflicts of interest and financial disclosures, and funding and support.

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Immediate Skin-to-Skin Contact in Very Preterm Neonates and Early Childhood Neurodevelopment

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, APRIL 16, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this randomized clinical trial, 2 hours of mother-neonate skin-to-skin contact (SSC) in the delivery room did not enhance neurodevelopmental outcomes at 2 to 3 years of age. However, the SSC group demonstrated improved breastfeeding practices up to 12 months compared with standard care, suggesting that the feasible and low-cost SSC intervention should be encouraged in clinical practice.

Corresponding Author: To contact the corresponding author, Laila Kristoffersen, RN, PhD, email laila.kristoffersen@ntnu.no.

 

(doi:10.1001/jamanetworkopen.2025.5467)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Social Risk at Individual vs Neighborhood Levels and Health Care Use in Medicaid Enrollees

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Plastic Waste and COVID-19 Incidence Among Hospital Staff After Deescalation in PPE Use

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Rurality and Area Deprivation and Outcomes After Out-of-Hospital Cardiac Arrest

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Screening History, Stage at Diagnosis, and Mortality in Screen-Detected Breast Cancer

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, TUESDAY, APRIL 15, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this cohort study of older women with screen-detected estrogen receptor–positive or human epidermal growth factor receptor 2–negative breast cancer, prior screening mammography was associated with earlier stage at breast cancer diagnosis and lower breast cancer mortality. These findings support the potential for routine screening to improve breast cancer outcomes. As with all observational studies, this study is limited by the potential effects of other differences between the screening and nonscreening groups.

Corresponding Author: To contact the corresponding author, Michaela A. Dinan, PhD, email michaela.dinan@yale.edu.

 

(doi:10.1001/jamanetworkopen.2025.5322)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Sex-Based Differences in Binge and Heavy Drinking Among US Adults

JAMA

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, APRIL 16, 2025

Media advisory: The full study is linked to this news release.

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About The Study: This analysis found that past-month binge drinking among young adult females in 2021-2023 was higher than males, reversing 2017-2019 patterns, whereas males in other age groups continued to binge and heavy drink at higher rates. These findings may be due to more rapid decreases in binge drinking over time among young adult males relative to females, or to plateauing or increases in binge drinking among females. Further investigation using other nationally representative surveys is needed to elucidate these explanations.

Corresponding Author: To contact the corresponding author, Bryant Shuey, MD, MPH, email bryant.shuey@pitt.edu.

 

(doi:10.1001/jama.2025.2726)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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A Digital Depression Treatment Program for Adults Treated in Primary Care

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Adolescent Disparities in Exposure to Adverse Childhood Experiences by Gender Identity

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Incidence of Pancreas and Colorectal Adenocarcinoma in the US

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, MONDAY, APRIL 14, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: The findings of this cohort study suggest that the incidence of pancreatic adenocarcinoma has increased among all age groups, whereas that of colorectal adenocarcinoma has increased among younger age groups. Clinicians should be aware of this trend when evaluating younger patients with relevant symptoms.

Corresponding Author: To contact the corresponding author, Arvind J. Trindade, MD, email arvind.trindade@gmail.com.

 

(doi:10.1001/jamanetworkopen.2025.4682)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Gestational Age and Cognitive Development in Childhood

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, MONDAY, APRIL 14, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this cross-sectional study of children ages 9 to 10, moderately preterm birth was associated with long-term cognitive problems independent of socioeconomic status, genetics, and other risk factors. These findings underscore the need for continued follow-up of all preterm children, with particular focus on those born before 34 weeks’ gestational age, because they may face greater developmental challenges over time.

Corresponding Author: To contact the corresponding author, Samson Nivins, PhD, email samson.nivins@ki.se.

 

(doi:10.1001/jamanetworkopen.2025.4580)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Projected Lifetime Cancer Risks From Current Computed Tomography Imaging

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, APRIL 14, 2025

Media advisory: The full study and editor’s note are linked to this news release.  

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https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/10.1001/jamainternmed.2025.0505?guestAccessKey=afde7c2e-df6b-4e7b-9ced-7a15ed74dc1d&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=041425

 

About The Study: This study found that at current utilization and radiation dose levels, computed tomography examinations in 2023 were projected to result in approximately 103,000 future cancers over the course of the lifetime of exposed patients. If current practices persist, computed tomography-associated cancer could eventually account for 5% of all new cancer diagnoses annually. 

Corresponding Author: To contact the corresponding author, Rebecca Smith-Bindman, MD, email rebecca.smith-bindman@ucsf.edu.

 

(doi:10.1001/jamainternmed.2025.0505)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Drug Decriminalization in British Columbia and Changes in Drug Crime and Opioid and Stimulant Harms

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Responses to the Gaza-Israel Conflict by Specialty Medical Societies

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Risk Factors for Severe Disease Among Children Hospitalized With RSV

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, APRIL 11, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this cohort study of children hospitalized with respiratory syncytial virus (RSV) in 2022 and 2023, severe RSV disease was more likely among those age 2 or older with pulmonary and neurologic, neuromuscular, or developmental conditions. For children younger than 2 years, age younger than 6 months and prematurity were the main risk factors. These findings support prevention strategies for all younger children, including premature infants, with potential benefit for children age 2 or older in specific high-risk groups.

Corresponding Author: To contact the corresponding author, Peter J. Gill, MD, DPhil, MSc, email peter.gill@sickkids.ca.

 

(doi:10.1001/jamanetworkopen.2025.4666)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Kidney Function Following COVID-19 in Children and Adolescents

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, APRIL 11, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this large U.S. cohort study of children and adolescents, SARS-CoV-2 infection was associated with a higher risk of adverse postacute kidney outcomes, particularly among those with preexisting chronic kidney disease or acute kidney injury, suggesting the need for vigilant long-term monitoring.

Corresponding Author: To contact the corresponding author, Yong Chen, PhD, email ychen123@pennmedicine.upenn.edu.

 

(doi:10.1001/jamanetworkopen.2025.4129)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Childcare Barriers and Appointment Nonadherence Among Women in a Safety-Net Health System

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Neighborhood Characteristics and Mental Health From Childhood to Adolescence

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, APRIL 10, 2025

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this cohort study of children and adolescents, associations between neighborhood characteristics and mental health evolved from childhood through adolescence. These findings suggest that targeted interventions in disadvantaged neighborhoods and strategies to protect young children from air pollution are essential. A comprehensive approach is recommended to incorporate air pollution, green space, and socioeconomic status not only in residential neighborhoods but also in other settings, such as schools.

Corresponding Author: To contact the corresponding author, Niloofar Shoari, PhD, email n.shoari@ucl.ac.uk.

 

(doi:10.1001/jamanetworkopen.2025.4470)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Influenza Vaccination Among People With Medicare by Race and Ethnicity, Education, and Rurality

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, APRIL 10, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this cross-sectional survey study, although overall influenza vaccination rates changed little from 2019 to 2022, they increased substantially for Black and Hispanic older adults, particularly those in rural areas, and decreased for some groups of white older adults. Determining the reasons for these divergent changes in influenza vaccination rates is a high priority for future research.

Corresponding Author: To contact the corresponding author, Marc N. Elliott, PhD, email elliott@rand.org.

 

(doi:10.1001/jamanetworkopen.2025.4462)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Automating the Addiction Behaviors Checklist for Problematic Opioid Use Identification

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Clinician Suicide Risk Assessment for Prediction of Suicide Attempt in a Large Health Care System

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Concordance of 30-Day Mortality and In-Hospital Mortality or Hospice Discharge After Sepsis

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Cardioprotective Glucose-Lowering Agents and Dementia Risk

JAMA Neurology

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, APRIL 7, 2025

Media advisory: The full study and editorial are linked to this news release.

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About The Study: While cardioprotective glucose-lowering therapies were not associated with an overall reduction in all-cause dementia, this meta-analysis of randomized clinical trials found that glucose lowering with glucagon-like peptide-1 receptor agonists (GLP-1RAs) was associated with a statistically significant reduction in all-cause dementia.

Corresponding Author: To contact the corresponding author, Catriona Reddin, MD, email reddin.catriona@gmail.com.

 

(doi:10.1001/jamaneurol.2025.0360)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Opioid Cap Laws and Opioid Prescriptions After Total Joint Replacements in Older Adults

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, APRIL 9, 2025

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: The findings of this study suggest that the New York opioid restriction law was associated with reductions in opioid quantities in the immediate total joint replacement postoperative period. Additional refinements may further reduce opioid prescribing in New York, and these findings may serve as a foundation for refining laws in other states that may not achieve their intended targets or have not implemented similar laws.

Corresponding Author: To contact the corresponding author, Caroline P. Thirukumaran, MBBS, MHA, PhD, email caroline.thirukumaran@northwestern.edu.

 

(doi:10.1001/jamanetworkopen.2025.4448)

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Pregnancy-Related Deaths in the US, 2018-2022

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, APRIL 9, 2025

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: In this cross-sectional analysis of pregnancy-related deaths in the U.S., rates increased during 2018 to 2022, with large variations by state and race and ethnicity. The concerning rates in the U.S. should be an urgent public health priority.

Corresponding Author: To contact the corresponding author, Yingxi Chen, MD, PhD, email yingxi.chen@nih.gov.

 

(doi:10.1001/jamanetworkopen.2025.4325)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Mortality Among Veterans With Opioid Use Disorder After Medical Hospitalization

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Hospital Addiction Consultation Service and Opioid Use Disorder Treatment

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Antenatal Opioid Exposure and Global and Regional Brain Volumes in Newborns

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GLP-1RA and SGLT2i Medications for Type 2 Diabetes and Alzheimer Disease and Related Dementias

JAMA Neurology

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, APRIL 7, 2025

Media advisory: The full study and editorial are linked to this news release.

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About The Study: In people with type 2 diabetes, both glucagon-like peptide-1 receptor agonists (GLP-1RAs) and sodium-glucose cotransporter-2 inhibitors (SGLT2is) were statistically significantly associated with decreased risk of Alzheimer disease and related dementias compared with other glucose-lowering drugs, and no difference was observed between both drugs.

Corresponding Author: To contact the corresponding author, Jingchuan Guo, MD, PhD, email guoj1@ufl.edu.

 

(doi:10.1001/jamaneurol.2025.0353)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Neighborhood Disadvantage, Individual Experiences of Racism, and Breast Cancer Survival

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, MONDAY, APRIL 7, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this cohort of Black women, living in disadvantaged neighborhoods was associated with a higher mortality from breast cancer, even after accounting for stage at diagnosis, treatments, and individual-level lifestyle factors. Community-level interventions to reduce environmental stressors and improve conditions in disadvantaged neighborhoods, including access to high-quality cancer care, may be critical to reducing racial disparities in breast cancer survival.

Corresponding Author: To contact the corresponding author, Etienne X. Holder, PhD, MPH, email exholder@bu.edu.

 

(doi:10.1001/jamanetworkopen.2025.3807)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Implementation of an Organization-Based Couples Health Promotion Program to Improve Physician Well-Being

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Mediterranean Diet, Physical Activity, and Bone Health in Older Adults

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, APRIL 8, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: In the PREDIMED-Plus trial, an energy-reduced Mediterranean diet and physical activity lifestyle intervention mitigated weight loss– and age-related bone mineral density decline among older women with metabolic syndrome compared with conventional ad libitum Mediterranean diet recommendations. Weight-loss lifestyle interventions with longer follow-up are warranted in the future to confirm these results in relation to bone health.

Corresponding author: To contact the corresponding authors, email Jesús F. García-Gavilán, Ph.D. (jesusfrancisco.garcia@urv.cat), and Jordi Salas-Salvadó, M.D., Ph.D. (jordi.salas@urv.cat).

 

(doi: 10.1001/jamanetworkopen.2025.3710)

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Health Care Practitioner Bias and Access to Inpatient Rehabilitation Services Among Survivors of Violence

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, APRIL 8, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: In this mixed-methods qualitative study of hospital patients discharged to rehabilitation centers, significant disparities in denials for admission were observed among survivors of violence, who were disproportionally Black or Hispanic. Stigmatizing language found in medical records suggested that bias within the referral process may have contributed to these disparities. These findings underscore the need for reformed clinical documentation practices and enhanced oversight of rehabilitation referral processes to promote equitable access to care.

Corresponding author: To contact the corresponding author, Megan R. Georges, M.S., email megan.georges@bmc.org.

 

(doi: 10.1001/jamanetworkopen.2025.4074)

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Perspectives on AI and Novel Technologies Among Older Adults, Clinicians, Payers, Investors, and Developers

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Trends in Extended-Release and Non–Extended-Release Buprenorphine Dispensing

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Trends in Access to Medications for Opioid Use Disorder

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About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

Invasive Group A Streptococcal Infections in 10 US States

JAMA

EMBARGOED FOR RELEASE: 11 A.M. ET, MONDAY, APRIL 7, 2025

Media advisory: The full study and editorial are linked to this news release.

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About The Study: Invasive group A Streptococcus infections increased substantially in 10 U.S. states during a surveillance period from 2013 to 2022. Accelerated efforts to prevent and control group A Streptococcus are needed, especially among groups at highest risk of infection.

Corresponding Author: To contact the corresponding author, Christopher J. Gregory, MD, MPH, email hgk4@cdc.gov.

 

(doi:10.1001/jama.2025.0910)

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USPSTF Recommendation Statement on Primary Care Behavioral Counseling Interventions to Support Breastfeeding

JAMA

EMBARGOED FOR RELEASE: 10:30 A.M. (ET), TUESDAY, APRIL 8, 2025

Media advisory: To contact the U.S. Preventive Services Task Force, email the Media Coordinator at Newsroom@USPSTF.net or call 301-951-9203. The full report and related articles are linked to this news release.

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Bottom Line: The U.S. Preventive Services Task Force (USPSTF) recommends providing interventions or referrals, during pregnancy and after birth, to support breastfeeding. The association between breastfeeding and health benefits in children has been previously well established; health benefits have also been found for women who breastfeed. However, breastfeeding rates in the U.S. are relatively modest; as of 2021, 59.8% of infants at age 6 months are breastfed and 27.2% of infants at that age are exclusively breastfed. The USPSTF routinely makes recommendations about the effectiveness of preventive care services and this recommendation updates and is consistent with the 2016 recommendation statement on primary care interventions to support breastfeeding.

 

(doi:10.1001/jama.2025.3650)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.

Note: More information about the U.S. Preventive Services Task Force, its process, and its recommendations can be found on the newsroom page of its website.

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Fine Particulate Matter From 2020 California Wildfires and Mental Health–Related Emergency Department Visits

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, APRIL 4, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: Wildfire smoke exposure was associated with significantly increased odds of subsequent emergency department visits for mental health conditions in this cross-sectional study, with varying lag times for different subconditions and demographic groups. Health care professionals and systems should prepare for a possible increase in demand for mental health–related emergency services during wildfire events.

Corresponding Author: To contact the corresponding author, Kari C. Nadeau, MD, PhD, email knadeau@hsph.harvard.edu.

 

(doi:10.1001/jamanetworkopen.2025.3326)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Gender Inequity in Institutional Leadership Roles in US Academic Medical Centers

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, APRIL 4, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: This systematic scoping review suggests that even though emphasis has been placed on addressing gender inequities in academic medicine, considerable disparities remain at the leadership level. While certain positions and specialties have been observed to have more female leaders, niches of academic medicine almost or completely exclude women from their leadership ranks. Importantly, even female-dominated specialties, such as obstetrics and gynecology, have substantial inequity in leadership roles. It is past time for organizational and systems-level changes to ensure equitable gender representation in academic leadership.

Corresponding Author: To contact the corresponding author, Marilyn Huang, MD, MS, email msh8f@uvahealth.org.

 

(doi:10.1001/jamanetworkopen.2025.2829)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Evaluation of AI Summaries on Interdisciplinary Understanding of Ophthalmology Notes

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Critical Illness, Major Surgery, and Other Hospitalizations and Active and Disabled Life Expectancy

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Packaging of Cannabis Edibles, Health Warning Recall, and Perceptions Among Young Adults

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Deporting Immigrants May Further Shrink the Health Care Workforce

JAMA

EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, APRIL 3, 2025

Media advisory: The full study is linked to this news release.

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About The Study: More than 1 million noncitizen immigrants (one-third of them undocumented) work in health care in the U.S. Their ranks include skilled personnel who would be difficult to replace, especially if legal immigration is further restricted. Many health care workers may be removed if President Trump implements plans to deport undocumented immigrants and those losing temporary protected status (e.g., from Haiti and Venezuela).

Corresponding Author: To contact the corresponding author, Lenore S. Azaroff, MD, ScD, email Lenore_Azaroff@yahoo.com.

 

(doi:10.1001/jama.2025.3544)

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Resident Physician Intentions Regarding Unionization

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, APRIL 3, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this survey study, most resident physicians reported either being in a union or supporting unionization at their institution, citing pay and financial security as critical factors in their consideration of unionization. Future research should investigate other factors and whether unionization achieves its goals of increased pay and benefits, work hours, and well-being.

Corresponding Author: To contact the corresponding author, Laura K. Barger, PhD, email lkbarger@hms.harvard.edu.

 

(doi:10.1001/jamanetworkopen.2025.3106)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Border Region Emergency Medical Services in Migrant Emergency Care

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, APRIL 3, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: The findings of this qualitative study of emergency medical services (EMS) clinicians suggest that migration has a complex, multidimensional influence on EMS clinicians in the border region. Deterrence-focused actions have not decreased the number of crossings but rather pushed migrants to cross in more dangerous ways, leading to more injuries and deaths. The findings suggest that the strain placed on local EMS clinicians is unsustainable and may be exacerbated by increased deterrence-based policies. Instead, border-region EMS clinicians need increased federal funding to support their work.

Corresponding Author: To contact the corresponding author, Christine Crudo Blackburn, PhD, email ccblackburn@tamu.edu.

 

(doi:10.1001/jamanetworkopen.2025.3111)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Uterine Fibroid Diagnosis by Race and Ethnicity in an Integrated Health Care System

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Operative vs Nonoperative Treatment for Adult Symptomatic Lumbar Scoliosis at 8-Year Follow-Up

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Functional vs Structural Cortical Deficit Pattern Biomarkers for Major Depressive Disorder

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Increased Utilization of Overtime and Agency Nurses and Patient Safety

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, APRIL 2, 2025

Media advisory: The full study and commentary are linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: The findings of this study suggest that both nurse overtime and nurse agency hours are associated with increased rates of pressure ulcers, a measure that is one of the most sensitive to nursing care. In future research, hospitals could use their own data to track safe thresholds.

Corresponding Author: To contact the corresponding author, Patricia Pittman, PhD, email ppittman@gwu.edu.

 

(doi:10.1001/jamanetworkopen.2025.2875)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Early-Life Ozone Exposure and Asthma and Wheeze in Children

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, APRIL 2, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this cohort study with relatively low ambient ozone exposure, early-life ozone was associated with asthma and wheeze outcomes at age 4 to 6 and in mixture with other air pollutants but not at age 8 to 9. Regulating and reducing exposure to ambient ozone may help reduce the significant public health burden of asthma among U.S. children.

Corresponding Author: To contact the corresponding author, Logan C. Dearborn, MPH, email dearbl@uw.edu.

 

(doi:10.1001/jamanetworkopen.2025.4121)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Spending on Glucagon-Like Peptide-1 Receptor Agonists Among US Adults

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, APRIL 2, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: Spending on glucagon-like peptide-1 receptor agonists (GLP-1 RAs) increased from 2018 to 2023, with the largest growth rates from 2022 to 2023. Although spending for certain GLP-1 RAs increased substantially, spending declined for others. This study estimated that more than $71 billion was spent on GLP-1 RAs and more than $50 billion on a product based on either semaglutide or tirzepatide molecules.

Corresponding Author: To contact the corresponding author, Stavros Tsipas, MA, email stavros.tsipas@ama-assn.org.

 

(doi:10.1001/jamanetworkopen.2025.2964)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Patient- and Community-Level Characteristics Associated With RSV Vaccination

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, TUESDAY, APRIL 1, 2025

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.2841?guestAccessKey=c0957767-f5eb-4d6d-88a4-15c747418b57&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=040125

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: Knowledge of respiratory syncytial virus (RSV) disease and RSV vaccine eligibility was low in this cross-sectional study of hospitalized adults. Older adults and those with certain medical conditions were more likely to have received vaccine, suggesting appropriate prioritization, but sociodemographic differences in vaccine uptake occurred.

Corresponding Author: To contact the corresponding author, Diya Surie, MD, email dsurie@cdc.gov.

 

(doi:10.1001/jamanetworkopen.2025.2841)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Intersectional Racial and Sex Disparities in Unintentional Overdose Mortality

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, TUESDAY, APRIL 1, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this cross-sectional study of overdose deaths, disparities in overdose mortality were evident, with Black men and Black women experiencing a pronounced and increasing burden of mortality compared with their white counterparts. Addressing these disparities will require a multipronged approach targeting the social, physical, economic, and policy risk environments.

Corresponding Author: To contact the corresponding author, Kechna Cadet, PhD, MPH, email kc3010@cumc.columbia.edu.

 

(doi:10.1001/jamanetworkopen.2025.2728)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Postpartum Hormonal Contraceptive Use and Risk of Depression

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, MONDAY, MARCH 31, 2025

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: Hormonal contraceptive initiation postpartum was associated with an instantaneous increased risk of developing depression in this cohort study. The associated risk was higher the earlier it was initiated postpartum, at least for combined oral contraceptives. This finding raises the issue of whether the incidence of depression postpartum is increased by routine hormonal contraceptive initiation after childbirth.

Corresponding Author: To contact the corresponding author, Vibe Gedsø Frokjaer, PhD, email vibe.frokjaer@nru.dk.

 

(doi:10.1001/jamanetworkopen.2025.2474)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Inclusion of Retracted Studies in Systematic Reviews and Meta-Analyses of Interventions

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Combination of Glucagon-Like Peptide 1 Receptor Agonist and Thiazolidinedione for Mortality and Cardiovascular Outcomes in Patients With Type 2 Diabetes

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Experiences of Obstetrician-Gynecologists Providing Pregnancy Care After Dobbs

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Trade Tariffs on Canadian Pharmaceuticals— Implications for US Drug Supply and Costs

JAMA

EMBARGOED FOR RELEASE: 11:15 A.M. ET, MONDAY, MARCH 31, 2025

Media advisory: The full study is linked to this news release.

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About The Study: Although Canada is not the largest supplier of medications to the U.S., tariffs could raise costs and strain supply chains. This study estimates that $3 billion in U.S. pharmaceuticals depend on Canadian manufacturing, with 25% tariffs adding $750 million in cost. Although the Inflation Reduction Act provisions limit cost pass-through to some payers (i.e., Medicare), manufacturers may still adjust production or alter distribution, increasing supply chain fragility.

Corresponding Author: To contact the corresponding author, Mina Tadrous, PharmD, PhD, email mina.tadrous@utoronto.ca.

 

(doi:10.1001/jama.2025.4583)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Leveraging Preexisting Cardiovascular Data to Improve the Detection and Treatment of Hypertension

JAMA Cardiology

EMBARGOED FOR RELEASE: 10 A.M. (ET), MONDAY, MARCH 31, 2025

Media advisory: The full study and editor’s note are linked to this news release. This study is being presented at the American College of Cardiology’s Annual Scientific Session.

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About The Study: In the NOTIFY-LVH randomized clinical trial, a centralized population health coordinator–led notification and clinical support pathway for individuals with left ventricular hypertrophy on prior echocardiograms increased the initial treatment of hypertension. This work highlights the potential benefit of leveraging preexisting but potentially underutilized cardiovascular data to improve health care delivery through mechanisms augmenting the traditional ambulatory care system.

Corresponding Author: To contact the corresponding author, Jason H. Wasfy, MD, MPhil, email jwasfy@mgh.harvard.edu.

 

(doi:10.1001/jamacardio.2025.0871)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflicts of interest and financial disclosures, and funding and support.

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Cardiovascular Health Among Rural and Urban US Adults— Healthcare, Lifestyle, and Social Factors

JAMA Cardiology

EMBARGOED FOR RELEASE: 11:30 A.M. (ET), MONDAY, MARCH 31, 2025

Media advisory: The full study and editorial are linked to this news release. This study is being presented at the American College of Cardiology’s Annual Scientific Session.

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About The Study: This national cross-sectional study found substantial rural-urban disparities in cardiometabolic risk factors and cardiovascular diseases, which were largest among younger adults and almost entirely explained by social risk factors. These findings suggest that efforts to improve socioeconomic conditions in rural communities may be critical to address the rural-urban gap in cardiovascular health.

Corresponding Author: To contact the corresponding author, Rishi K. Wadhera, MD, MPP, MPhil, email rwadhera@bidmc.harvard.edu.

 

(doi:10.1001/jamacardio.2025.0538)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflicts of interest and financial disclosures, and funding and support.

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Metal Concentrations in Blood and Cerebrospinal Fluid of Patients With Arthroplasty Implants

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Mortality Classification for Deaths With Nonfirearm Force by Police, 2012-2021

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Mode of Death in Patients With Heart Failure With Mildly Reduced or Preserved Ejection Fraction

JAMA Cardiology

EMBARGOED FOR RELEASE: 10 A.M. (ET), SUNDAY, MARCH 30, 2025

Media advisory: The full study is linked to this news release. This study is being presented at the American College of Cardiology’s Annual Scientific Session.

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About The Study: Among patients with heart failure with mildly reduced ejection fraction/heart failure with preserved ejection fraction in the Finerenone Trial to Investigate Efficacy and Safety Superior to Placebo in Patients With Heart Failure randomized clinical trial, higher proportions of cardiovascular and overall mortality in those with ejection fraction less than 50% were related principally to higher proportions of sudden death. A clear treatment effect of finerenone on cardiovascular or cause-specific mortality was not identified, although the trial was likely underpowered for these outcomes.

Corresponding Author: To contact the corresponding author, Akshay S. Desai, MD MPH, email adesai@bwh.harvard.edu.

 

(doi:10.1001/jamacardio.2025.0860)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflicts of interest and financial disclosures, and funding and support.

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Finerenone and Atrial Fibrillation in Heart Failure

JAMA Cardiology

EMBARGOED FOR RELEASE: 1 P.M. (ET), SATURDAY, MARCH 29, 2025

Media advisory: The full study is linked to this news release. This study is being presented at the American College of Cardiology’s Annual Scientific Session.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamacardiology/fullarticle/10.1001/jamacardio.2025.0848?guestAccessKey=4d81e04e-ccb5-4549-bea3-a65bd04cb4c3&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=032925

 

About The Study: The efficacy of finerenone was consistent regardless of atrial fibrillation status in this study. New-onset atrial fibrillation was associated with a substantially higher risk of subsequent outcomes.

Corresponding Author: To contact the corresponding author, John J. V. McMurray, MD, email john.mcmurray@glasgow.ac.uk.

 

(doi:10.1001/jamacardio.2025.0848)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflicts of interest and financial disclosures, and funding and support.

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