About The Study: When Omicron was the dominant variant during the early months of 2022 from January to April, COVID-19-associated hospitalization rates were 10.5 times higher in unvaccinated adults and 2.5 times higher in vaccinated adults with no booster dose compared with those who had received a booster dose. Results of the study suggest that clinicians and public health practitioners should continue to promote vaccination with all recommended doses for eligible persons.
Authors: Fiona Havers, M.D., M.H.S., of the Centers for Disease Control and Prevention in Atlanta, is the corresponding author.
(doi:10.1001/jamainternmed.2022.4299)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The findings of this study with 17,000 participants suggest that COVID-19 boosters or third doses were well tolerated by individuals who were pregnant and lactating. Data on COVID-19 vaccine boosters are particularly important as vaccine uptake during pregnancy is lagging, and strategies to reduce hesitancy, increase acceptance, and help guide discussions between pregnant and lactating persons and maternal care professionals are needed.
Authors: Alisa Kachikis, M.D., M.S., of the University of Washington in Seattle, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.30495)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this study of 219 patients with long COVID and neurologic symptoms, 64% had an impaired sense of smell, with the highest prevalence among women, adults, and those not hospitalized during the acute phase of COVID-19. Patients with an impaired sense of smell may develop severe loss of smell that may persist for more than 1 year after the onset of symptoms.
Authors: Luiz Fabio Magno Falcao, Ph.D., of Para State University in Belem, Brazil, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.30637)
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Authors: Marc G. Besselink, M.D., Ph.D., of the University of Amsterdam, is the corresponding author.
(doi:10.1001/jamasurg.2022.3702)
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About The Study: In this study of individuals followed up for more a year starting in April 2020, researchers found pre-infection psychological distress, including symptoms of depression, anxiety, worry about COVID-19, loneliness, and perceived stress, was strongly associated with the risk of post–COVID-19 conditions, sometimes called long COVID, among those infected with SARS-CoV-2.
Authors: Siwen Wang, M.D., of the Harvard T.H. Chan School of Medicine in Boston, is the corresponding author.
(10.1001/jamapsychiatry.2022.2640)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: This survey study found that although most registrants of a large professional society meeting held during the Omicron surge attended the meeting in person, rates of COVID-19 positivity were low and equivalent among in-person and virtual attendees. Conference organizers adapted planned safety measures to account for increased variant transmissibility and case numbers. These data suggest that among highly vaccinated clinicians with high risk of occupational exposure, cautious strategies to mitigate COVID-19 transmission during a surge were effective, and in-person meeting attendance posed no greater risk than professional hazards.
Authors: Callisia N. Clarke, M.D., M.S., of the Medical College of Wisconsin in Milwaukee, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.30300)
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Authors: Matthew T. James, M.D., Ph.D., of the University of Calgary in Calgary, Canada, is the corresponding author.
(doi:10.1001/jama.2022.13382)
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Authors: Denise A. O’Connor, Ph.D., of Monash University in Melbourne, Australia, is the corresponding author.
(doi:10.1001/jama.2022.14587)
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About The Study: Using World Health Organization excess mortality data, researchers estimate that 10.5 million children lost parents or caregivers and 7.5 million children experienced COVID-19–associated orphanhood through May 1, 2022.
Authors: Joel-Pascal Ntwali N’konzi, M.Sc., of the African Institute for Mathematical Sciences in Kigali, Rwanda, and Susan Hillis, Ph.D., of the University of Oxford in Oxford, United Kingdom, are the corresponding authors.
(doi:10.1001/jamapediatrics.2022.3157)
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About JAMA Health Forum: JAMA Health Forum has transitioned from an information channel to an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this study of nearly 2,400 patients who underwent a video telemedicine consultation followed by an in-person outpatient visit for the same clinical problem in the same specialty within a 90-day window, the provisional diagnosis established over video telemedicine visit matched the in-person reference standard diagnosis in 87% of cases. These findings suggest that video telemedicine visits yield a high degree of diagnostic concordance to in-person visits for most new clinical concerns.
Authors: Bart M. Demaerschalk, M.D., M.Sc., of the Mayo Clinic College of Medicine and Science in Phoenix, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.29958)
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About JAMA Health Forum: JAMA Health Forum has transitioned from an information channel to an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
About The Study: The findings of this study suggest that among a large commercially insured population, private equity acquisitions of 578 dermatology, gastroenterology, and ophthalmology physician practices were associated with increased health care spending and several measures of utilization.
Authors: Jane M. Zhu, M.D., M.P.P., M.S.H.P., of Oregon Health & Science University in Portland, is the corresponding author.
(doi:10.1001/jamahealthforum.2022.2886)
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About JAMA Health Forum: JAMA Health Forum has transitioned from an information channel to an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
About The Study: This analysis of data from a large primary care network found that telephones and tablets were used for most telehealth visits, and higher rates of telephone or tablet use were seen among patients who were younger, Black or Hispanic or Latino, and living in lower-income zip codes. These results may help inform efforts to increase access to telehealth.
Authors: Eric Bressman, M.D., M.S.H.P., of the University of Pennsylvania in Philadelphia, is the corresponding author.
(doi:10.1001/jamahealthforum.2022.2932)
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Authors: Nizar M. Tannir, M.D., of the University of Texas MD Anderson Cancer Center in Houston, is the corresponding author.
(doi:10.1001/jamaoncol.2022.3511)
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Authors: Thierry Conroy, M.D., of the Institut de Cancérologie de Lorraine in Vandoeuvre-lès-Nancy, France, is the corresponding author.
(doi:10.1001/jamaoncol.2022.3829)
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About The Study: Researchers conducted a genetic analysis of individuals with uncombable hair syndrome, a rare hair shaft anomaly that is characterized by dry, frizzy and wiry hair that cannot be combed flat. Only about 100 known cases have been reported so far.
Authors: Regina C. Betz, M.D., of the University of Bonn in Bonn, Germany, is the corresponding author.
(doi:10.1001/jamadermatol.2022.2319)
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About The Study: This article provides an overview of the current understanding of associations between the COVID-19 pandemic and mental health among pregnant and postpartum women and infant behavioral development.
Authors: Catherine Monk, Ph.D., of Columbia University in New York, is the corresponding author.
(10.1001/jamapsychiatry.2022.2591)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this study involving 690 participants from 175 households, SARS-CoV-2 infections were frequently asymptomatic in children age 4 and younger. The presence and number of symptoms did not correlate with viral load. These findings suggest that symptom screening may be insufficient to prevent outbreaks involving young children.
Authors: Ruth A. Karron, M.D., of Johns Hopkins University in Baltimore, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.27348)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
Visual Abstract
Authors: Francisco B. Ortega, Ph.D., of the University of Granada in Granada, Spain, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.27893)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: Researchers found a marked increase in the incidence and severity of abusive head trauma in infants during the COVID-19 pandemic period in the Paris metropolitan area compared with the pre-pandemic period. Although the containment and mitigation measures were necessary to reduce the spread of COVID-19, they may have had unintended health consequences for children, such as an increase in abusive head trauma. These results suggest the need for clinical awareness and preventive actions.
Authors: Flora Blangis, M.P.H., of the Universite Paris Cite in Paris, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.26182)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: This study found that rates of help-seeking consultations for domestic violence increased during the COVID-19 pandemic in Japan. This increase may be associated with a range of factors, including economic instability, increased exposure to exploitative relationships, and reduced support options.
Authors: Xerxes T. Seposo, Ph.D., M.P.H., of Hokkaido University in Sapporo, Japan, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.29421)
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Authors: Eric P. Hoffman, Ph.D., of School of Pharmacy and Pharmaceutical Sciences Binghamton University—State University of New York in Binghamton, is the corresponding author.
(doi:10.1001/jamaneurol.2022.2480)
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Authors: Eric J. Nelson, M.D., Ph.D., of the University of Florida in Gainesville, and Daniel T. Leung, M.D., M.Sc., of the University of Utah School of Medicine in Salt Lake City, are the corresponding authors.
(doi:10.1001/jamapediatrics.2022.2535)
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About The Study: After hearing and seeing simple instructional materials, children and adolescents ages 4 to 14 self-collected nasal swabs that closely agreed on SARS-CoV-2 detection with swabs collected by health care workers.
Authors: Wilbur A. Lam, M.D., Ph.D., and Greg S. Martin, M.D., M.Sc., of the Emory University School of Medicine in Atlanta, are the corresponding authors.
(doi:10.1001/jama.2022.14877)
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About The Study: This study assessed the presence of neutralizing antibodies in blood samples of children in different age groups up to 16 months after SARS-CoV-2 infection.
Authors: Chee Fu Yung, M.B.Ch.B., of the KK Women’s and Children’s Hospital in Singapore, is the corresponding author.
(doi:10.1001/jamapediatrics.2022.3072)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The findings of this survey study suggest that medical school programs designed to increase the diversity of the physician workforce were disrupted by the COVID-19 pandemic. The long-term outcomes of these disruptions are unknown.
Authors: Sonal Batra, M.D., M.S.T., of George Washington University in Washington, D.C., is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.29086)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: Hospitals and health systems administered more than 158,000 anti–SARS-CoV-2 monoclonal antibodies (mAbs) doses in early 2022 despite Food and Drug Administration (FDA) deauthorization because of a lack of efficacy against the Omicron variant. Medicare payments for mAb administration range from $450 to $750 per dose, indicating that spending on these deauthorized treatments likely exceeds $71 million. The findings suggest that the use of deauthorized mAb products was widespread, even though patients had a minimal likelihood of benefit.
Authors: Timothy S. Anderson, M.D., M.A.S., of Beth Israel Deaconess Medical Center in Boston, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.28997)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The results of this study of 14,000 household beneficiaries of a COVID-19 test kit program in six communities suggest that application-based reporting with incentives may be associated with increased reporting of rapid tests for COVID-19. However, increasing its use may be a critical first step.
Authors: Apurv Soni, M.D., Ph.D., of the University of Massachusetts Chan Medical School in Worcester, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.28885)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: This study of 2.4 million adults in Singapore investigated levels of protection against severe COVID-19 and confirmed SARS-CoV-2 infection across several vaccine types, vaccine combinations and time since last dose.
Authors: Oon Tek Ng, M.R.C.P., of the National Centre for Infectious Diseases in Singapore, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.28900)
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About JAMA Health Forum: JAMA Health Forum has transitioned from an information channel to an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
About The Study: Researchers examined the association between changes in Medicaid managed care coverage of substance use services and admissions for substance use treatment in Maryland and Nebraska from 2010 to 2019.
Authors: Samantha G. Auty, M.S., of the Boston University School of Public Health, is the corresponding author.
(doi:10.1001/jamahealthforum.2022.2812)
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About JAMA Health Forum: JAMA Health Forum has transitioned from an information channel to an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
About The Study: The findings of this analysis suggest that although there were modest improvements in the average quality of care offered by high-premium Medicare Advantage plans, plans with high quality of care are available at every premium level.
Authors: Marc N. Elliott, Ph.D., of the RAND Corporation in Santa Monica, California, is the corresponding author.
(doi:10.1001/jamahealthforum.2022.2826)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
Visual Abstract
Authors: Jeremy D. Keenan, M.D., M.P.H., of the University of California, San Francisco, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.28244)
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Authors: Verinder S. Sidhu, M.S., of the Ingham Institute for Applied Medical Research in Liverpool, Australia, is the corresponding author.
(doi:10.1001/jama.2022.13416)
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Authors: Jun Ma, M.D., of Sun Yat-sen University Cancer Center in Guangzhou, China, is the corresponding author.
(doi:10.1001/jama.2022.13997)
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EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, AUGUST 23, 2022
Media advisory: To contact the U.S. Preventive Services Task Force, email the Media Coordinator at Newsroom@USPSTF.net or call 301-951-9203. The full report and related articles are linked to this news release.
Bottom Line: The U.S. Preventive Services Task Force (USPSTF) recommends that for primary prevention of cardiovascular disease (CVD) in adults ages 40 to 75 who have one or more CVD risk factors (i.e., dyslipidemia, diabetes, hypertension, or smoking), clinicians should prescribe a statin for those with an estimated 10-year CVD risk of 10% or greater and selectively offer a statin for those with an estimated risk of 7.5% to less than 10%. The USPSTF concludes that the current evidence is insufficient to make a recommendation about initiating a statin for the primary prevention of CVD events and mortality in adults age 76 or older. Cardiovascular disease is the leading cause of death in the United States, the cause of more than 1 of every 4 deaths. The USPSTF routinely makes recommendations about the effectiveness of preventive care services, and this recommendation replaces and is generally consistent with its 2016 recommendation.
(doi:10.1001/jama.2022.13044)
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Note: More information about the U.S. Preventive Services Task Force, its process, and its recommendations can be found on the newsroom page of its website.
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About The Study: This study of 2.8 million commercially insured adults found an association between chronic disease diagnoses and adverse credit report outcomes, with increasing rates of medical debt in collections, nonmedical debt in collections, total delinquent debt, low credit score and recent bankruptcy as an individual’s number of chronic conditions increased.
Authors: Nora V. Becker, M.D., Ph.D., of the University of Michigan in Ann Arbor, is the corresponding author.
(doi:10.1001/jamainternmed.2022.3687)
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About The Study: This study of nearly 660,000 children who were tested for SARS-CoV-2 by antigen or polymerase chain reaction examined the symptoms, diagnosed health conditions and medications associated with SARS-CoV-2 infection four weeks or more following the initial test.
Authors: Suchitra Rao, M.B.B.S., M.S.C.S., of the University of Colorado School of Medicine and Children’s Hospital Colorado in Aurora, is the corresponding author.
(doi:10.1001/jamapediatrics.2022.2800)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The findings of this systematic review and meta-analysis of 141 articles suggest that with the evolution of mutant strains, the incubation period of COVID-19 decreased gradually from Alpha (5 days) to Omicron variant (3.42 days). Identifying the incubation period of different variants is a key factor in determining the isolation period.
Authors: Min Liu, Ph.D., of Peking University in Beijing, and Wannian Liang, Ph.D., of Tsinghua University in Beijing, are the corresponding authors.
(doi:10.1001/jamanetworkopen.2022.28008)
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About JAMA Health Forum: JAMA Health Forum has transitioned from an information channel to an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this survey study of 135,000 adults, less than half (48.5%) of individuals who had been fully vaccinated nationwide had received a booster dose. Marked variations were seen across geographic locations, occupation types, and other sociodemographic characteristics. Targeted efforts at populations with low uptake may be needed to improve booster vaccine coverage.
Authors: Israel T. Agaku D.M.D., M.P.H., M.B.A., Ph.D., of NYC Health + Hospitals in New York, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.27680)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Health Forum: JAMA Health Forum has transitioned from an information channel to an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
About The Study: In this observational study of nearly 720,000 pharmacy claims data, out-of-pocket cost of naloxone had been an increasingly substantial barrier to naloxone access for uninsured patients, potentially limiting use among this population, which constituted approximately 20% of adults with opioid use disorder.
Authors: Evan D. Peet, Ph.D., of the RAND Corporation in Pittsburgh, is the corresponding author.
(doi:10.1001/jamahealthforum.2022.2663)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Health Forum: JAMA Health Forum has transitioned from an information channel to an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
About The Study: Researchers compared the prevalence of human papillomavirus (HPV) among women born in the 1980s versus the 1990s and a pre-HPV vaccination period (2005-2006) versus a recent vaccination period (2015-2016).
Authors: Ashish A. Deshmukh, Ph.D., M.P.H., of the University of Texas Health Science Center School of Public Health in Houston, is the corresponding author.
(doi:10.1001/jamahealthforum.2022.2706)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Authors: Chigusa Morizane, M.D., Ph.D., of the National Cancer Center Hospital in Tokyo, is the corresponding author.
(doi:10.1001/jamaoncol.2022.3395)
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About The Study: Researchers compared visual acuity testing at home with visual acuity testing in a clinical setting.
Authors: Michael D. Crossland, Ph.D., of the UCL Institute of Ophthalmology in London, is the corresponding author.
(doi:10.1001/jamaophthalmol.2022.3182)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The results of this survey of health departments suggest that the annual incidence rate of COVID-19 was lower among people experiencing homelessness than in the general population at state and local levels. A national estimate and the extent of under- or overestimation of the incidence rate remain unknown.
Authors: Ashley A. Meehan, M.P.H., of the Centers for Disease Control and Prevention in Atlanta, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.27248)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: This analysis at a large urban hospital found a severe decline in surgical procedure volumes across a multitude of subspecialties during the COVID-19 peak and that after the peak and vaccine release periods the overall volume did not fully recover, with inconsistent recovery rates across subspecialties. Further research and hospital-level changes are needed to address the backlog of surgical services.
Authors: Marc D. Succi, M.D., of Massachusetts General Hospital in Boston, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.27443)
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About The Study: In this systematic review and meta-analysis comprising 26 studies from five continents totaling more than 100,000 women, the risk of developing postpartum depression was almost twice as high among mothers who had a family history of psychiatric disorders compared with mothers without a family history.
Authors: Mette-Marie Zacher Kjeldsen, M.Sc., of Aarhus University in Aarhus, Denmark, is the corresponding author.
(10.1001/jamapsychiatry.2022.2400)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The results of this study in Los Angeles County of 210 adults with recent Omicron variant infection suggest that more than half were unaware of their infectious status and that awareness was higher among health care employees than nonemployees, yet it was still low overall. Unawareness may be a key contributor to rapid transmission of the virus within communities.
Authors: Susan Cheng, M.D., M.P.H., of Cedars-Sinai Medical Center in Los Angeles, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.27241)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: Researchers estimated the long-term effectiveness associated with the Pfizer-BioNTech COVID-19 vaccine against SARS-CoV-2 infection and critical infection among 3.2 million adolescents in South Korea.
Authors: Young-Joon Park, M.D., M.P.H., of the Korea Disease Control and Prevention Agency in Cheongju, South Korea, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.27205)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
Visual Abstract
Authors: Deborah F. Tate, Ph.D., of the University of North Carolina at Chapel Hill, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.26561)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: This analysis of 1,977 clinical trials investigating therapeutics and vaccines for COVID-19 found that most were funded by public sources (58%), followed by industry (27%) and public-private partnerships (15%). Most of these clinical trials focused on COVID-19 therapeutics (85%) as opposed to vaccines (15%).
Authors: Elias Mossialos, Ph.D., of the London School of Economics and Political Science, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.26892)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Authors: Hui-Sheng Chen, M.D., of the General Hospital of Northern Theatre Command in Shenyang, China, is the corresponding author.
(doi:10.1001/jama.2022.13123)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Authors: Mark J. Pletcher, M.D., M.P.H., of the University of California, San Francisco, is the corresponding author.
(doi:10.1001/jamainternmed.2022.3355)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this study of rural communities in 10 states, 79% of people using drugs reported past-30-day methamphetamine use. Nonfatal overdose was greatest in people using both methamphetamine and opioids vs opioids or methamphetamine alone. People using both substances reported the least access to treatment. These findings suggest that harm reduction and substance use disorder treatment interventions must address methamphetamine use as well as opioids to decrease overdose in rural communities.
Authors: P. Todd Korthuis, M.D., M.P.H., of Oregon Health & Science University in Portland, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.26544)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: Gout was more common in adults self-reporting Black race during a recent 10-year period compared with their white counterparts in this nationally representative study. These racial differences may be explained by sex-specific differences in diet and social determinants of health and clinical factors. Culturally informed efforts focusing on these factors could reduce current gout-related disparities.
Authors: Natalie McCormick, Ph.D., of Massachusetts General Hospital in Boston, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.26804)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this study of nearly 3,200 individuals who were injured while using electric scooters or bicycles in Oslo, Norway, electric scooter riders, compared with bicyclists, were younger, less frequently wearing a helmet, more often intoxicated and were more often injured at night. The rate of intoxication among electric scooter riders injured at night was high. Preventive measures, including awareness campaigns, regulating electric scooter availability, improving infrastructure, and implementing stricter helmet and alcohol policies, may prove effective for reducing injuries.
Authors: August Vincent Stray, M.D., D.D.S., of Oslo University Hospital in Oslo, Norway, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.26701)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: Researchers compared the risk of infection with SARS-CoV-2 among 2,900 health care workers by preferred mask type and level of exposure to patients with COVID-19.
Authors: Philipp Kohler, M.D., M.Sc., of Cantonal Hospital St. Gallen in St. Gallen, Switzerland, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.26816)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Health Forum: JAMA Health Forum has transitioned from an information channel to an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
About JAMA Health Forum: JAMA Health Forum has transitioned from an information channel to an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: Among 127,000 patients with a positive SARS-CoV-2 test, health care use was elevated six months after the acute infection compared with patients with negative SARS-CoV-2 test results. These findings suggest that health care systems should consider long-term strategic resource allocation in response to the expected elevated health care use experienced by patients with SARS-CoV-2 infection.
Authors: Sara Y. Tartof, Ph.D., M.P.H., of Kaiser Permanente Southern California in Pasadena, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.25657)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: During the first 14 months of the COVID-19 pandemic there were small but significant increases in pregnancy-related complications and maternal death during delivery hospitalization in this study of more than 1.6 million pregnant patients across 463 hospitals. The number of live births decreased by 5.2%. Further efforts are needed to ensure risks potentially associated with the COVID-19 pandemic do not persist beyond the current state of the pandemic.
Authors: Rose L. Molina, M.D., M.P.H., of the Beth Israel Deaconess Medical Center in Boston, is the corresponding author.
(doi:10.1001/jamanetworkopen.2022.26531)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Health Forum: JAMA Health Forum has transitioned from an information channel to an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
About The Study: Researchers examined the association of direct-to-consumer advertising of prescription drugs with consumer intentions and beliefs related to prescription drugs and health-related behaviors in this study that included 2,874 individuals at risk of cardiovascular disease.
Authors: Matthew D. Eisenberg, Ph.D., of the Johns Hopkins Bloomberg School of Public Health in Baltimore, is the corresponding author.
(doi:10.1001/jamahealthforum.2022.2570)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About The Study: In this study that included 584 immunocompromised patients with hematologic cancers, a third Moderna COVID-19 vaccination was associated with significantly improved SARS-CoV-2 antibody concentrations comparable to those obtained by healthy individuals after the standard two-dose Moderna vaccination schedule.
Authors: Mette D. Hazenberg, M.D., Ph.D., of the University of Amsterdam, is the corresponding author.
(doi:10.1001/jamaoncol.2022.3227)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About The Study: The findings of this survey study suggest that COVID-19 vaccine initiation is lower among adults with vision or hearing disabilities compared with adults without disabilities. This information may inform initiatives to promote equitable and accessible vaccination.
Authors: Kea Turner, Ph.D., M.P.H., M.A., of the Moffitt Cancer Center in Tampa, Florida, is the corresponding author.
(doi:10.1001/jamaophthalmol.2022.3041)
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Authors: Lize Xiong, M.D., Ph.D., of the Shanghai Fourth People’s Hospital Affiliated to Tongji University School of Medicine in Shanghai, and Hailong Dong, M.D., Ph.D., of the Fourth Military Medical University in Xi’an, China, are the corresponding authors.
(doi:10.1001/jamasurg.2022.3338)
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