COVID-19 Symptoms 6 Months After Onset, Role of Vaccination for SARS-CoV-2 Infection

JAMA Network Open


Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.


About The Study: In this study of 1,832 U.S. adults, the risk of reporting symptoms for 28 or more days after COVID-19 onset was significantly higher in participants who were unvaccinated at the time of infection and those who reported moderate or severe acute illness symptoms. At six months after onset, participants had significantly higher risk of pulmonary, diabetes, neurological, and mental health encounters versus pre-infection baseline. 

Authors: Stephanie A. Richard, Ph.D., of the Uniformed Services University of the Health Sciences in Bethesda, Maryland, is the corresponding author. 



Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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