Medical Marijuana Legalization and Opioid- and Pain-Related Outcomes Among Patients Receiving Cancer Treatment

JAMA Oncology

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, DECEMBER 1, 2022

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaoncology/fullarticle/10.1001/jamaoncol.2022.5623?guestAccessKey=492f0176-1a29-4c42-8737-9cad14a67fd4&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=120122

 

About The Study: The findings of this study suggest that medical marijuana legalization implemented from 2012 to 2017 was associated with a lower rate of opioid dispensing and pain-related hospital events among some adults receiving treatment for newly diagnosed cancer. The nature of these associations and their implications for patient safety and quality of life need to be further investigated. 

Authors: Yuhua Bao, Ph.D., of Weill Cornell Medicine in New York, is the corresponding author. 

 

(doi:10.1001/jamaoncol.2022.5623)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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SARS-COV-2 Positivity, Patient-Reported Well-being 3 Months After Symptomatic Illness

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, DECEMBER 1, 2022

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2022.44486?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=120122

About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: In this study of 1,000 adults with symptomatic illness, participants in both the COVID-19–positive and COVID-19–negative groups reported persistently poor physical, mental, or social well-being at 3-month follow-up. Although some individuals had clinically meaningful improvements over time, many reported moderate to severe impairments in well-being 3 months later. These results highlight the importance of including a control group of participants with negative COVID-19 results for comparison when examining the sequelae of COVID-19. 

Authors: Lauren E. Wisk, Ph.D., of the David Geffen School of Medicine at the University of California in Los Angeles, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2022.44486)

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Effect of Nudges to Clinicians, Patients, or Both to Increase Statin Prescribing

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Geographical, Urban-Rural Disparities in Cardiac Rehabilitation Eligibility, Center-Based Use

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Evaluation of the Safety, Effectiveness of Nutritional Supplements for Treating Hair Loss

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Association Between College Course Delivery Model, Rates of Psychological Distress During Pandemic

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, NOVEMBER 30, 2022

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: Researchers found in this study of a nationwide data set that included 59,000 full-time undergraduate students that those attending fully online classes reported higher levels of psychological distress than students attending a mix of online and in-person classes. 

Authors: Cindy H. Liu, Ph.D., of Brigham and Women’s Hospital in Boston, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2022.44270)

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Accuracy in Patient Understanding of Common Medical Phrases

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, NOVEMBER 30, 2022

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: The findings of this survey study of 215 adults suggest that several common phrases are misunderstood when used in a medical setting, with the interpreted meaning frequently the exact opposite of what is intended. 

Authors: Michael Pitt, M.D., of the University of Minnesota in Minneapolis, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2022.42972)

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Trends, Disparities in Firearm Fatalities in the US, 1990-2021

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, NOVEMBER 29, 2022

Media advisory: The full study and commentary are linked to this news release.

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: Researchers found in this study of 1.1 million firearm fatalities in the United States from 1990 to 2021 marked disparities in firearm fatality rates between men and women and by racial and ethnic group, and these disparities increased in recent years. These findings suggest that public health approaches to reduce firearm violence should consider underlying demographic and geographic trends and differences by intent. 

Authors: Chris A. Rees, M.D., M.P.H., of the Emory University School of Medicine in Atlanta, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2022.44221)

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Examining Association of Accessibility of Retail Cannabis, Prenatal Cannabis Use During Pandemic in California

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, NOVEMBER 29, 2022

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2022.44086?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=112922

About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: In this study of 99,000 pregnancies screened for prenatal cannabis use via urine toxicology testing before and during the COVID-19 pandemic in California, prenatal cannabis use was more common among individuals living in areas with greater retail availability of cannabis. Although relative rates increased similarly during the pandemic regardless of local cannabis retail and policy environment, there was a larger absolute increase associated with living closer to a storefront cannabis retailer. Continued monitoring of local cannabis policy, the retail environment, and prenatal cannabis use is needed. 

Authors: Kelly C. Young-Wolff, Ph.D., M.P.H., of Kaiser Permanente Northern California in Oakland, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2022.44086)

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Analysis of Failure Rates for COVID-19 Entrance Screening at an Academic Medical Center

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Vitamin D Supplementation, Development Among School-age Children in an Area With Vitamin D Deficiency

JAMA Pediatrics

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, NOVEMBER 28, 2022

Media advisory: The full study is linked to this news release.

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About The Study: Researchers found in this secondary analysis of a randomized clinical trial including 8,800 school-age children with a high prevalence of vitamin D deficiency that weekly oral administration of vitamin D for 3 years did not influence growth, body composition, or pubertal development. Vitamin D deficiency is prevalent among children living in temperate climates and has been reported to associate independently with stunting and obesity. 

Authors: Davaasambuu Ganmaa, Ph.D., of the Harvard T.H. Chan School of Public Health in Boston, and Adrian R. Martineau, Ph.D., of the Queen Mary University of London, are the corresponding authors.

 

(doi:10.1001/jamapediatrics.2022.4581)

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In Utero Exposure to Maternal Injury, Associated Risk of Cerebral Palsy

JAMA Pediatrics

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, NOVEMBER 28, 2022

Media advisory: The full study and editorial are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapediatrics/fullarticle/10.1001/jamapediatrics.2022.4535?guestAccessKey=6d15a7df-af57-4166-9049-40003551ef09&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=112822

 

About The Study: In this study of approximately 2 million births, maternal unintentional injury during pregnancy was associated with an increased risk of cerebral palsy in children, particularly among those who were exposed to maternal injuries that resulted in hospitalization and those who were delivered shortly after the injury. Public health professionals and stakeholders should be aware of these potential long-term consequences on offspring when designing programs and providing recommendations about safety during pregnancy. Early monitoring and developmental assessment of children exposed to maternal injury might be warranted.

Authors: Asma Ahmed, M.D., Ph.D., M.P.H., of the Hospital for Sick Children Research Institute in Toronto, is the corresponding author.

 

(doi:10.1001/jamapediatrics.2022.4535)

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Estimating the Length of Preclinical Detectable Phase for Open-Angle Glaucoma

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Safety, Efficacy of Robotic vs Open Liver Resection for Hepatocellular Carcinoma

JAMA Surgery

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, NOVEMBER 23, 2022

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamasurgery/fullarticle/10.1001/jamasurg.2022.5697?guestAccessKey=2db7ccf1-7c2d-4280-98e0-b9cdc8b2d151&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=112322

 

About The Study: The findings of this study comparing robotic liver resection with open liver resection suggest that robotic liver resection is a safe treatment strategy for patients with hepatocellular carcinoma, the most common type of primary liver cancer, and those with compromised liver function while achieving oncologic efficacy. 

Authors: Fabrizio Di Benedetto, M.D., and Stefano Di Sandro, M.D., of the University of Modena and Reggio Emilia in Modena, Italy, are the corresponding authors.

 

(doi:10.1001/jamasurg.2022.5697)

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Disparities in Inclusion of Racial, Ethnic Minority Groups in Prostate Cancer Clinical Trials

JAMA Oncology

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, NOVEMBER 23, 2022

Media advisory: The full is linked to this news release.

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About The Study: The results of this meta-analysis of 286 randomized clinical trials including 9,500 patients suggest that Black and Hispanic men are underrepresented in trials compared with their share of prostate cancer incidence. The representation of Black patients has consistently remained low during the past 2 decades. 

Authors: Irbaz Bin Riaz, M.B.B.S., M.S., of Harvard Medical School in Boston, is the corresponding author. 

 

(doi:10.1001/jamaoncol.2022.5511)

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Association of Benzodiazepine Treatment for Sleep Disorders With Drug Overdose Risk Among Young People

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, NOVEMBER 22, 2022

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: The findings of this study suggest that benzodiazepines, compared with alternative pharmacologic treatments for common sleep disorders, were associated with an increased risk of drug overdose among young people ages 10 to 29 during the following 6-month period, especially among those with a recent opioid prescription. Drug overdose is an important safety consideration when treating young people with benzodiazepines. 

Authors: Greta A. Bushnell, Ph.D., of the Rutgers University School of Public Health in Piscataway, New Jersey, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2022.43215)

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Association of Prenatal Exposure to Benzodiazepines With Development of Autism Spectrum, Attention-Deficit/Hyperactivity Disorders

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, NOVEMBER 22, 2022

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: Researchers found in this study of 1.5 million children that after adjusting for possible confounders and accounting for possible parental genetic or familial factors, benzodiazepine exposure during pregnancy was not associated with increased risks of autism spectrum disorder or attention-deficit/hyperactivity disorder. These results challenge current assumptions of a potential association of neurodevelopmental disorders with maternal benzodiazepine use before or during pregnancy. 

Authors: Yi-Lung Chen, Ph.D., of Asia University in Taichung, Taiwan, and Mong-Liang Lu, M.D., M.S., of Taipei Medical University in Taipei, Taiwan, are the corresponding authors. 

 

(doi:10.1001/jamanetworkopen.2022.43282)

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Reported Awareness, Adoption of 2021 Estimated Glomerular Filtration Rate Equations Among US Clinical Laboratories

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Effect of Regular, Low-Dose, Extended-release Morphine on Chronic Breathlessness in COPD

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https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2022.20206?guestAccessKey=e930c49a-b2de-40d3-9fa6-7e1adbb95185&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=112222

Effect of Virtual Reality Environment Using Domed Ceiling Screen on Procedural Pain During IV Placement in Young Children

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Association of Youth Suicides, Mental Health Professional Workforce Shortages

JAMA Pediatrics

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, NOVEMBER 21, 2022

Media advisory: The full study and editorial are linked to this news release.

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About The Study: Researchers found in this study of 5,034 youth ages 5 to 19 who died by suicide from 2015 to 2016 that the suicide rate increased as county levels of mental health professional shortages increased, after adjusting for county demographic and socioeconomic characteristics. These findings may inform suicide prevention efforts.

Authors: Jennifer A. Hoffmann, M.D., M.S., of Ann & Robert H. Lurie Children’s Hospital of Chicago, is the corresponding author.

 

(doi:10.1001/jamapediatrics.2022.4419)

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Return on Investment of the COVID-19 Vaccination Campaign in New York City

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, NOVEMBER 21, 2022

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: In this decision analytical model study of a citywide initiative, every $1 invested in the New York City COVID-19 vaccination campaign yielded estimated savings of $10.19 in direct and indirect costs of health outcomes that would have been incurred without vaccination. The findings of this study suggest that COVID-19 vaccination in New York City was associated with reduction in severe outcomes and avoidance of substantial economic losses. 

Authors: Alison P. Galvani, Ph.D., of the Yale School of Public Health in New Haven, Connecticut, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2022.43127)

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Reforming Reimbursement for FDA’s Accelerated Approval Program to Support State Medicaid Programs

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About JAMA Health Forum: JAMA Health Forum has transitioned from an information channel to an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

Effect of Patient Portal Outreach Messages on Well Child Care Visit Completion

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, NOVEMBER 18, 2022

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2022.42853?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=111822

About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: In this randomized clinical trial that included 945 patients ages 6 to 17, outreach messages delivered via electronic health record patient portals increased the rates of scheduling and completing well child care visits and receiving the COVID-19 vaccine, providing a useful tool to help restore well child care in populations whose care was delayed during the pandemic. 

Authors: Anne E. Berset, B.A., of the Cincinnati Children’s Hospital Medical Center, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2022.42853)

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Association of NFL Fan Attendance With County-Level COVID-19 Incidence in 2020-2021 Season

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, NOVEMBER 18, 2022

Media advisory: The full study and commentary are linked to this news release.

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: In this cross-sectional study of the presence of fans at National Football League (NFL) home games during the 2020-2021 season, results indicated that fan attendance was associated with increased levels of COVID-19 in the counties in which the venues are nested within, as well as in surrounding counties. The spikes in COVID-19 for crowds of over 20,000 people suggest that large events should be handled with extreme caution during public health event(s) where vaccines, on-site testing, and various countermeasures are not readily available to the public. 

Authors: Wanda E. Leal, Ph.D., of Sam Houston State University in Huntsville, Texas, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2022.40132)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Association of Recreational Cannabis Legalization With Alcohol Use Among Adults

JAMA Health Forum

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, NOVEMBER 18, 2022

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama-health-forum/fullarticle/10.1001/jamahealthforum.2022.4069?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=111822

About JAMA Health Forum: JAMA Health Forum has transitioned from an information channel to an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

 

About The Study: This study including 4.2 million adults in all 50 states from 2010 to 2019 found that recreational cannabis laws may be associated with increased alcohol use, primarily among younger adults and men. These findings suggest that increased alcohol use may be an unintended consequence of recreational cannabis laws.

Authors: Coleman Drake, Ph.D., of the University of Pittsburgh School of Public Health, is the corresponding author.

 

(doi:10.1001/jamahealthforum.2022.4069)

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Increased Delay in Diagnosis, But Not Treatment, Among Patients With Oral Cancer During COVID-19

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Association of Physical Activity With Risk of Mortality Among Breast Cancer Survivors

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, NOVEMBER 17, 2022

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2022.42660?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=111722

About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: The results of this study that included 315 women suggest that even moderate physical activity was associated with a 60% lower risk of death among breast cancer survivors. The mortality risk was similar among participants who were active and those with moderate physical activity levels. The findings further suggest that survivorship care plans should consider incorporating physical activity because even moderate activity may be vital for extending survival as well as health-related quality of life. 

Authors: Reina Haque, Ph.D., M.P.H., of Kaiser Permanente Southern California in Pasadena, California, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2022.42660)

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Association of Residential Racial, Economic Segregation With Cancer Mortality

JAMA Oncology

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, NOVEMBER 17, 2022

Media advisory: The full study and commentary are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaoncology/fullarticle/10.1001/jamaoncol.2022.5382?guestAccessKey=64d5e78b-c977-480e-bec8-a7a695fb5338&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=111722

 

About The Study: The findings of this study of 3,110 U.S. counties suggest that residential racial and economic segregation is associated with higher cancer mortality at the county level, highlighting opportunities for geographically targeted cancer prevention and control efforts. 

Authors: Lu Zhang, Ph.D., of Clemson University in Clemson, South Carolina, is the corresponding author. 

 

(doi:10.1001/jamaoncol.2022.5382)

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Rates of Routine Cancer Screening, Diagnosis Before vs After Pandemic

JAMA Oncology

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, NOVEMBER 17, 2022

Media advisory: The full study is linked to this news release.

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About The Study: In this cross-sectional study of data from January 2017 to December 2021, population-based screening and diagnosis remained below pre-pandemic levels for breast, cervical and colorectal cancer. The findings suggest that screening quickly rebounded after the initial stages of the pandemic; however, the longer follow-up time reveals that gaps in preventive cancer screening returned and worsened. 

Authors: Allison H. Oakes, Ph.D., of Trilliant Health in Brentwood, Tennessee, is the corresponding author. 

 

(doi:10.1001/jamaoncol.2022.5481)

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Diversity, Goals of Graduating Medical Students Pursuing Careers in Dermatology

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Diversity Trends Among Dermatology Resident Trainees Compared With Other Specialties

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https://jamanetwork.com/journals/jamadermatology/fullarticle/10.1001/jamadermatol.2022.4991?guestAccessKey=868fdf0e-630d-44d1-a885-0cd197948c5c&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=111622

Association Between Loneliness, Postoperative Mortality Among Medicare Patients

JAMA Surgery

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, NOVEMBER 16, 2022

Media advisory: The full study is linked to this news release.

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About The Study: In this study of 4,400 Medicare patients, self-reported loneliness was associated with an increased risk of death at 30 days after non-elective surgery. The findings suggest that loneliness may be an important social determinant of postoperative outcomes, particularly for non-elective care.

Authors: Jennifer F. Waljee, M.D., M.P.H., of the Center for Healthcare Outcomes and Policy in Ann Arbor, Michigan, is the corresponding author.

 

(doi:10.1001/jamasurg.2022.4784)

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COVID-19 Vaccination Status Among Parents of Hospitalized Children With SARS-CoV-2 Infection

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, NOVEMBER 16, 2022

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2022.42295?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=111622

About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: Researchers found in this study that parental vaccination was associated with a reduced risk of COVID-19 hospitalization in children younger than age 5 during the Delta and Omicron waves. These results reinforce recommendations for widespread vaccination of parents of young children.

Authors: François Angoulvant, M.D., Ph.D., of Lausanne University Hospital in Lausanne, Switzerland, is the corresponding author.

  

(doi:10.1001/jamanetworkopen.2022.42295

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Association of Maternal Preeclampsia With Offspring Risks of Ischemic Heart Disease, Stroke

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, NOVEMBER 15, 2022

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2022.42064?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=111522

About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: Results of this study involving almost 8.5 million participants in Nordic countries suggest that offspring born to individuals with preeclampsia had increased ischemic heart disease and stroke risk that were not fully explained by preterm or small for gestational age birth, and that the associated risks for stroke were higher for severe forms of preeclampsia. 

Authors: Fen Yang, M.D., M.Sc., of the Karolinska Institutet in Stockholm, and Imre Janszky, M.D., Ph.D., of the Norwegian University of Science and Technology in Trondheim, Norway, are the corresponding authors. 

 

(doi:10.1001/jamanetworkopen.2022.42064)

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Post–COVID-19 Symptoms 2 Years After SARS-CoV-2 Infection Among Hospitalized vs Non-hospitalized Patients

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, NOVEMBER 15, 2022

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: This cross-sectional study suggested the presence of at least one post–COVID-19 symptom in 59.7% of hospitalized patients and 67.5% of non-hospitalized patients two years after infection. Small differences in symptoms at onset of COVID-19 were identified between hospitalized and non-hospitalized patients. Post–COVID-19 symptoms were similar between hospitalized and non-hospitalized patients; however, lack of inclusion of uninfected controls limits the ability to assess the association of SARS-CoV-2 infection with overall and specific post–COVID-19 symptoms two years after acute infection. Future studies should include uninfected control populations. 

Authors: Cesar Fernandez-de-las-Penas, P.T., Ph.D., of the Universidad Rey Juan Carlos in Madrid, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2022.42106)

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Association of Physical Activity With Neurofilament Light Chain Trajectories in Autosomal Dominant Frontotemporal Lobar Degeneration Variant Carriers

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Associations Between State-Level Changes in Reproductive Health Services, Indicators of Severe Maternal Morbidity

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Brain Aging Among Racially, Ethnically Diverse Middle-Age, Older Adults

JAMA Neurology

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, NOVEMBER 14, 2022

Media advisory: The full study is linked to this news release.

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About The Study: In this study of two community-based cohort studies in midlife (n = 497) and late life (n = 970), racial and ethnic disparities in small vessel cerebrovascular disease were apparent in midlife. In Latinx and white adults, brain aging was more pronounced in late life than midlife, whereas Black adults showed an accelerated pattern of brain aging beginning in midlife. Race and ethnicity disparities in aging and Alzheimer disease and related dementias may be due partially to social forces that accelerate brain aging, especially in Black middle-age adults.

Authors: Adam M. Brickman, Ph.D., of Columbia University in New York, is the corresponding authors.

 

(doi:10.1001/jamaneurol.2022.3919)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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USPSTF Recommendation Statement on Screening for Obstructive Sleep Apnea in Adults

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, NOVEMBER 15, 2022

Media advisory: To contact the U.S. Preventive Services Task Force, email the Media Coordinator at Newsroom@USPSTF.net or call 301-951-9203. The full report and related articles are linked to this news release.

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Bottom Line: The U.S. Preventive Services Task Force (USPSTF) concludes that the current evidence is insufficient to make a recommendation about screening for obstructive sleep apnea (OSA) in the general adult population. This statement applies to asymptomatic adults and adults with unrecognized symptoms of OSA. Current prevalence of OSA in the United States is not well established. In 2007-2010 the estimated prevalence of at least mild OSA plus symptoms of daytime sleepiness among adults ages 30 to 70 was 14% for men and 5% for women, and the estimated prevalence of moderate to severe OSA was 13% for men and 6% for women. Adverse health outcomes associated with untreated OSA include cardiovascular disease and cerebrovascular events, type 2 diabetes, cognitive impairment, decreased quality of life, and motor vehicle crashes. Severe OSA is associated with increased all-cause mortality. The USPSTF routinely makes recommendations about the effectiveness of preventive care services and this statement is consistent with its 2017 recommendation on screening for OSA.

(doi:10.1001/jama.2022.20304)

 

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.

Note: More information about the U.S. Preventive Services Task Force, its process, and its recommendations can be found on the newsroom page of its website.

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Visual Abstract: Effect of Extending the Duration of Pre-quit Treatment With Varenicline on Smoking Abstinence

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, NOVEMBER 11, 2022

Media advisory: The full study is linked to this news release. A visual abstract is below.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2022.41731?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=111122

About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

Visual Abstract

Authors: Larry W. Hawk Jr., Ph.D., of the University at Buffalo in Buffalo, New York, is the corresponding author.

(doi:10.1001/jamanetworkopen.2022.41731)

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Visual Abstract: Comparison of Acupuncture vs Sham Acupuncture in Treatment of Aromatase Inhibitor–Related Joint Pain

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, NOVEMBER 11, 2022

Media advisory: The full study is linked to this news release. A visual abstract is below.

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

Visual Abstract

Authors: Dawn L. Hershman, M.D., M.S., of the Columbia University Irving Medical Center in New York, is the corresponding author.

(doi:10.1001/jamanetworkopen.2022.41720)

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Electronic Health Record Legal Settlements Since 2009 Health Information Technology for Economic and Clinical Health Act

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About JAMA Health Forum: JAMA Health Forum has transitioned from an information channel to an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

Financial Outcomes After Traumatic Injury Among Working-Age Adults With Commercial Insurance

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About JAMA Health Forum: JAMA Health Forum has transitioned from an information channel to an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

Early Adoption of Anti–SARS-CoV-2 Pharmacotherapies Among Veterans With Mild to Moderate COVID-19

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, NOVEMBER 11, 2022

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2022.41434?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=111122

About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: In this study of more than 111,000 veterans who tested positive for SARS-CoV-2 during January and February 2022 when supply of outpatient COVID-19 pharmacotherapies was limited, prescription of these pharmacotherapies was underused, and many veterans with risk factors for severe COVID-19 did not receive treatment. Veterans from minority racial and ethnic groups were less likely to receive any pharmacotherapy. 

Authors: Kristina L. Bajema, M.D., M.Sc., of the Veterans Affairs Portland Health Care System in Portland, Oregon, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2022.41434)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Food Insufficiency Following Discontinuation of Child Tax Credit Among Lower-Income Households

JAMA Health Forum

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, NOVEMBER 11, 2022

Media advisory: The full study is linked to this news release.

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About JAMA Health Forum: JAMA Health Forum has transitioned from an information channel to an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

 

About The Study: Discontinuation of monthly Child Tax Credit payments in December 2021 was associated with a significant increase in household food insufficiency among lower-income households, with the greatest increase occurring in the lowest-income households, according to survey data from the U.S. Census Bureau.

Authors: Zoe Bouchelle, M.D., of the University of Pennsylvania in Philadelphia, is the corresponding author.

 

(doi:10.1001/jamahealthforum.2022.4039)

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Association Between Social Disparities, Ear Infection Treatment in Children

JAMA Otolaryngology–Head & Neck Surgery

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, NOVEMBER 10, 2022

Media advisory: The full study is linked to this news release.

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About The Study: The findings of this study of 4.8 million children with otitis media (infection of the middle ear) and commercial insurance suggest that those who were socially disadvantaged were less likely to receive treatment and more likely to experience complications for undertreated otitis media. As otitis media is a modifiable risk factor for hearing loss, efforts need to be made to ensure equitable access to treatment for all children. 

Authors: Z. Jason Qian, M.D., of the Stanford University School of Medicine in Stanford, California, is the corresponding author.

 

(doi:10.1001/jamaoto.2022.3560)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Perspectives of Emergency Clinicians About Medical Errors Resulting in Patient Harm or Malpractice Litigation

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, NOVEMBER 10, 2022

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2022.41461?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=111022

About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: This cross-sectional study investigated emergency department clinicians’ concerns about medical errors resulting in either patient harm or malpractice litigation. 

Authors: Linda M. Isbell, Ph.D., of the University of Massachusetts Amherst, is the corresponding author.

  

(doi:10.1001/jamanetworkopen.2022.41461)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Preexisting Neuropsychiatric Conditions, Associated Risk of Severe COVID-19 Infection, Other Acute Respiratory Infections

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Results of a Remotely Delivered Hypertension, Lipid Program Across a Diverse Health Care Network

JAMA Cardiology

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, NOVEMBER 9, 2022

Media advisory: The full study and commentary are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamacardiology/fullarticle/10.1001/jamacardio.2022.4018?guestAccessKey=0ca9cc74-23c4-44db-b1d5-38e3583d5461&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=110922

 

About The Study: The results of this study that included more than 10,000 patients with blood pressure and/or cholesterol levels above guideline-recommended targets indicate that a standardized remote blood pressure and cholesterol management program may help optimize guideline-directed therapy at scale, reduce cardiovascular risk, and minimize the need for in-person visits among diverse populations. 

Authors: Benjamin M. Scirica, M.D., M.P.H., of Brigham and Women’s Hospital in Boston, is the corresponding author.

 

(doi:10.1001/jamacardio.2022.4018)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflicts of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Racial, Ethnic Disparities in Buprenorphine Treatment Duration

JAMA Psychiatry

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, NOVEMBER 9, 2022

Media advisory: The full study is linked to this news release.

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About The Study: This analysis found that racial and ethnic disparities in buprenorphine treatment duration increased between 2006 and 2020, particularly during more recent years. Buprenorphine is used to treat opioid use disorder and reduce overdose risk. Duration of buprenorphine treatment is a measure of quality of care; longer retention is associated with superior clinical outcomes.

Authors: Mohammad S. Jalali, Ph.D., of Harvard Medical School in Boston, is the corresponding author.

 

(10.1001/jamapsychiatry.2022.3673)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Treatment Time, In-Hospital Mortality Among Patients With ST-Segment Elevation Heart Attack, 2018-2021

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Association of State-Level Firearm Deaths With Firearm Laws in Neighboring States

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, NOVEMBER 8, 2022

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2022.40750?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=110822

About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: In this pooled analysis involving firearm laws and firearm-related deaths from 2000 to 2019 in the 48 contiguous states, a permit requirement for purchasing all firearms had an interstate association with decreased total firearm-related deaths and homicide, whereas the prohibition of firearm possession for individuals who have committed a violent misdemeanor had an interstate association with decreased firearm suicide. These findings suggest that synergic legislative action to implement firearm laws in proximate states may help prevent firearm-related deaths.

Authors: Ye Liu, M.D., M.P.H., of the University of Alabama at Birmingham, is the corresponding author.

  

(doi:10.1001/jamanetworkopen.2022.40750)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Analysis of Electrolyte Abnormalities in Adolescents, Adults and Subsequent Diagnosis of an Eating Disorder

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, NOVEMBER 8, 2022

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2022.40809?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=110822

About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: In this case-control study of individuals age 13 or older without a prior eating disorder diagnosis, researchers found that an outpatient electrolyte abnormality was associated with an over 2-fold higher odds of a subsequent eating disorder diagnosis. The median time from the earliest electrolyte abnormality to eating disorder diagnosis exceeded one year. These results suggest that otherwise unexplained outpatient electrolyte abnormalities may serve to identify individuals who should be screened for an underlying eating disorder.

Authors: Gregory L. Hundemer, M.D., M.P.H., of the University of Ottawa in Ottawa, Canada, is the corresponding author.

 

 (doi:10.1001/jamanetworkopen.2022.40809)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Changes in Distribution of Severe Neurologic Involvement in Pediatric Inpatients With COVID-19 or Multisystem Inflammatory Syndrome in Children in 2021 vs 2020

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Daily Low-Dose Aspirin, Risk of Serious Falls, Fractures in Healthy Older Adults

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/10.1001/jamainternmed.2022.5028?guestAccessKey=9e5db703-5cd3-45d9-8344-72e06f6828cf&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=110722