EMBARGOED FOR RELEASE: 6:30 A.M. (ET), MONDAY, SEPTEMBER 11, 2023
Media advisory: The full study and editorial are linked to this news release. This study is being released to coincide with presentation at the European Respiratory Society International Congress 2023.
About The Study: In this dose-response meta-analysis that included nine randomized clinical trials and 2,980 patients, compared with placebo, gefapixant (45 mg orally twice daily) led to modest improvements in cough frequency, cough severity, and cough-specific quality of life but increased taste-related adverse events.
Authors: Imran Satia, M.D., Ph.D., of McMaster University in Hamilton, Ontario, Canada, is the corresponding author.
(doi:10.1001/jama.2023.18035)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About The Study: In this study of prospectively collected data of 49,000 adults age 60 or older participating in the UK Biobank, more time spent in sedentary behaviors was significantly associated with higher incidence of all-cause dementia. Future research is needed to determine whether the association between sedentary behavior and risk of dementia is causal.
Authors: David A. Raichlen, Ph.D., of the University of Southern California in Los Angeles, is the corresponding author.
(doi:10.1001/jama.2023.15231)
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: This meta-analysis including individual participant data from 34,000 older adults in 17 studies found that antihypertensive use was associated with decreased dementia risk compared with individuals with untreated hypertension through all ages in late life. Individuals with treated hypertension had no increased risk of dementia compared with healthy controls.
Authors: Matthew J. Lennon, M.D., of the University of New South Wales in Sydney, Australia is the corresponding author.
(doi: 10.1001/jamanetworkopen.2023.33353)
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this study of Medicare beneficiaries with comorbid chronic low back pain and opioid use disorder (OUD), receipt of physical therapy and chiropractic care was low overall and lower across most racial and ethnic minority groups compared with non-Hispanic white persons. The findings underscore the need to address inequities in guideline-concordant pain management, particularly among Black or African American and Hispanic persons with OUD.
Authors: Patience Moyo, Ph.D., of the Brown University School of Public Health in Providence, Rhode Island is the corresponding author.
(doi: 10.1001/jamanetworkopen.2023.33251)
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About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this study of health care workers who received a COVID-19 vaccine, an influenza vaccine, or both, co-administration was not associated with substantially inferior immune response or to more frequent adverse events compared with COVID-19 vaccine administration alone, supporting the co-administration of these vaccines.
Authors: Gili Regev-Yochay, M.D., of the Sheba Medical Center in Ramat Gan, Israel, is the corresponding author.
(doi:10.1001/jamanetworkopen.2023.32813)
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The findings of this study suggest that childhood survivors of acute respiratory distress syndrome (ARDS) are at high risk of readmission in the first two months after discharge. Future studies should evaluate whether post-discharge interventions (e.g., telephonic contact, follow-up clinics, and home health care) may help reduce the readmission burden.
Authors: Garrett Keim, M.D., of Children’s Hospital of Philadelphia, is the corresponding author.
(doi:10.1001/jamanetworkopen.2023.30774)
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About The Study: Calcium channel blocker use was adversely associated with glaucoma prevalence in this study of 427,000 adult UK Biobank participants, suggesting that calcium channel blockers may represent an important modifiable risk factor for glaucoma, potentially through an intraocular pressure–independent mechanism.
Authors: Alan Kastner, M.D., M.Sc., of the Moorfields Eye Hospital National Health Service Foundation Trust and University College London Institute of Ophthalmology in London, is the corresponding author.
(doi:10.1001/jamaophthalmol.2023.3877)
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this randomized clinical trial including 64 transgender and gender-diverse adults, immediate testosterone therapy compared with no treatment significantly reduced gender dysphoria, depression, and suicidality in transgender and gender-diverse individuals desiring testosterone therapy.
Authors: Ada S. Cheung, M.B.B.S., Ph.D., of Austin Health in Heidelberg, Victoria, Australia, is the corresponding author.
(doi:10.1001/jamanetworkopen.2023.31919)
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: Long- and short-term heat exposure during pregnancy was associated with higher risk of severe maternal morbidity in this study with 403,000 pregnancies from 2008 to 2018 in Southern California. These results might have important implications for severe maternal morbidity prevention, particularly in a changing climate.
Authors: Jun Wu, Ph.D., of the University of California, Irvine, is the corresponding author.
(doi:10.1001/jamanetworkopen.2023.32780)
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About The Study: Researchers identified decreases of in situ and invasive melanoma diagnoses during 2020, which may reflect decreased skin cancer screening examinations or access to dermatologic care during the pandemic, both of which may lead to reduced melanoma diagnoses. This study adds to the current literature by highlighting that the relative increase in thick melanomas in 2020 was primarily associated with a marked decrease in thin melanomas, rather than an absolute increase in thicker melanomas.
Authors: Rebecca I. Hartman, M.D., M.P.H., of Brigham and Women’s Hospital in Boston, is the corresponding author.
(doi:10.1001/jamadermatol.2023.2712)
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: This study found large increases in cannabis involvement in emergency department visits for traffic injury over time in Ontario, Canada, which may have accelerated following nonmedical cannabis commercialization. Although the frequency of visits was rare, they may reflect broader changes in cannabis-impaired driving. Greater prevention efforts, including targeted education and policy measures, in regions with legal cannabis are indicated.
Authors: Daniel T. Myran, M.D., M.P.H., of the University of Ottawa in Ottawa, Ontario, Canada, is the corresponding author.
(doi:10.1001/jamanetworkopen.2023.31551)
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About The Study: In a study of children ages 16 to 30 months assessed for autism in six specialty clinics, eye-tracking–based measurement of social visual engagement was predictive of autism diagnoses by clinical experts. Further evaluation of this test’s role in early diagnosis and assessment of autism in routine specialty clinic practice is warranted.
Authors: Warren Jones, Ph.D., of Children’s Healthcare of Atlanta, is the corresponding author.
(doi:10.1001/jama.2023.13295)
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In two diagnostic studies of 1,089 children younger than age 3, objective eye-tracking–based measurements of social visual engagement quantified diagnostic status as well as individual levels of social disability, verbal ability, and nonverbal ability in autism. These findings suggest that objective measurements of social visual engagement can be used to aid in autism diagnosis and assessment.
Authors: Warren Jones, Ph.D., of Children’s Healthcare of Atlanta, is the corresponding author.
(doi:10.1001/jamanetworkopen.2023.30145)
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About The Study: Risk-standardized survival rates for out-of-hospital cardiac arrest were 1.9% lower at emergency medical service (EMS) agencies working in Black and Hispanic catchment areas than in white catchment areas in this study including 764 EMS agencies. This difference was not explained by EMS response times, rates of EMS termination of resuscitation, or first responder rates of initiating cardiopulmonary resuscitation or applying an automated external defibrillator. These findings suggest there is a need for further assessment of these discrepancies.
Authors: Paul S. Chan, M.D., M.Sc., Saint Luke’s Hospital Mid America Heart Institute in Kansas City, is the corresponding author.
(doi:10.1001/jamainternmed.2023.4303)
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About The Study: This study found that between 1995 and 2020, U.S. preterm infant mortality improved among all categories of prematurity. Inequalities in preterm infant mortality based on maternal race and ethnicity have remained constant while socioeconomic disparities have widened over time.
Authors: Tim Venkatesan, M.A. (Cantab), M.B., B.Chir., D.T.M.&H., of the UCL Great Ormond Street Institute of Child Health in London, is the corresponding author.
(doi:10.1001/jamapediatrics.2023.3487)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this study of 633,000 children treated in 586 emergency departments across 11 states, mortality of Black children was greater than that of white children at all quartile levels of readiness among those with acute medical emergencies but not traumatic injuries. Increased readiness was associated with decreased mortality overall, and it decreased most for Black children with acute medical emergencies.
Authors: Peter C. Jenkins, M.D., M.Sc., of the Indiana University School of Medicine in Indianapolis, is the corresponding author.
(doi:10.1001/jamanetworkopen.2023.32160)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
About The Study: The results of this study suggest that a weighted lottery to allocate scarce resources is feasible and may result in more drug allocation to individuals who reside in disadvantaged neighborhoods and who identify as Black; however, Black individuals allocated the drug may be less likely to accept allocation and receive it.
Authors: Erin K. McCreary, Pharm.D., of the University of Pittsburgh School of Medicine, is the corresponding author.
(doi:10.1001/jamahealthforum.2023.2774)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The findings of this study suggest that telehealth medication abortion services (tele-MAB) facilitates abortion care access for those further from brick-and mortar abortion facilities and, thus, may mitigate the impacts of travel logistics and costs. Additionally, tele-MAB may better meet the needs of those with prior abortion experience, perhaps due to greater familiarity with the abortion process.
Authors: Anna E. Fiastro, M.P.H., M.E.M., Ph.D., of the University of Washington in Seattle, is the corresponding author.
(doi:10.1001/jamanetworkopen.2023.31900)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The results of this study including 11.7 million adults in Ontario, Canada, suggest that the absence of a prioritization strategy for access to critical care treatment may be a factor in significantly greater SARS-CoV-2–associated mortality in patients with cancer.
Authors: Kelvin K.W. Chan, M.D., Ph.D., of ICES in Toronto, is the corresponding author.
(doi:10.1001/jamanetworkopen.2023.31617)
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About The Study: In a randomized clinical trial with 104 participants, psilocybin treatment was associated with a clinically significant sustained reduction in depressive symptoms and functional disability, without serious adverse events. These findings add to increasing evidence that psilocybin—when administered with psychological support—may hold promise as a novel intervention for major depressive disorder.
Authors: Charles L. Raison, M.D., of Usona Institute in Fitchburg, Wisconsin, is the corresponding author.
(doi:10.1001/jama.2023.14530)
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About The Study: The findings of this study suggest that patients with cancer had a disparate burden of COVID-19 mortality during the winter Omicron wave compared with the general U.S. population. With the emergence of new, immune-evasive SARS-CoV-2 variants, many of which are anticipated to be resistant to monoclonal antibody treatments, strategies to prevent COVID-19 transmission should remain a high priority.
Authors: Chi-Fu Jeffrey Yang, M.D., of Massachusetts General Hospital in Boston, is the corresponding author.
(doi:10.1001/jamaoncol.2023.3066)
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About The Study: The findings of this study of 150,000 patients who were operated on by 2,553 surgeons in Sweden indicate that female surgeons have more favorable outcomes and operate more slowly than male surgeons in elective and acute care cholecystectomies. These results may contribute to an increased understanding of gender differences within this surgical specialty.
Authors: My Blohm, M.D., of the Karolinska Institutet in Stockholm, is the corresponding author.
(doi:10.1001/jamasurg.2023.3736)
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About The Study: The results of this study of one million patients suggest that patients treated by female surgeons have a lower risk-adjusted likelihood of adverse postoperative outcomes at 90 days and one year following surgery. These findings further support differences in patient outcomes based on physician sex that warrant deeper study regarding underlying causes and potential solutions.
Authors: Christopher J. D. Wallis, M.D., Ph.D., of the University of Toronto, is the corresponding author.
(doi:10.1001/jamasurg.2023.3744)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this study of 31 million pregnant individuals who delivered between 2010 and 2018, infertility treatment was associated with an increased risk of stroke-related hospitalization within 12 months of delivery; this risk was evident as early as 30 days after delivery. Timely follow-up in the immediate days postpartum and continued long-term follow-up should be considered to mitigate stroke risk.
Authors: Cande V. Ananth, Ph.D., M.P.H., of the Rutgers Robert Wood Johnson Medical School in New Brunswick, New Jersey, is the corresponding author.
(doi:10.1001/jamanetworkopen.2023.31470)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The results of this study of 61,000 mother-child dyads suggest that postnatal selective serotonin reuptake inhibitor (SSRI) treatment was associated with a reduced risk of postnatal depression–associated maternal mental health problems and child externalizing behaviors across early childhood years. These findings suggest that postnatal SSRI treatment may bring benefits in the long term to women with postnatal depression and their offspring.
Authors: Chaoyu Liu, M.D., Ph.D., of King’s College in London, is the corresponding author.
(doi:10.1001/jamanetworkopen.2023.31270)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this study of primary care patients in a state with legal recreational cannabis use, cannabis use disorder (CUD) was common among patients who used cannabis. Moderate to severe CUD was more prevalent among patients who reported any nonmedical use. These results underscore the importance of assessing patient cannabis use and CUD symptoms in medical settings.
Authors: Gwen T. Lapham, Ph.D., M.P.H., M.S.W., of the Kaiser Permanente Washington Health Research Institute in Seattle, is the corresponding author.
(doi:10.1001/jamanetworkopen.2023.28934)
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EMBARGOED FOR RELEASE: 10:30 A.M. (ET), MONDAY, AUGUST 28, 2023
Media advisory: The full study and commentary are linked to this news release. This study is being released to coincide with presentation at the European Society of Cardiology Congress 2023.
About The Study: The clinical benefits of mavacamten in this phase 3 randomized clinical trial of 81 Chinese patients with symptomatic obstructive hypertrophic cardiomyopathy were consistent with previous data. This study supports the efficacy and safety of mavacamten, a first-in-class, selective, reversible, allosteric inhibitor of β-cardiac myosin, in diverse populations, including Chinese patients.
Authors: Shuyang Zhang, M.D., of the Chinese Academy of Medical Sciences and Peking Union Medical College in Beijing, is the corresponding author.
(doi:10.1001/jamacardio.2023.3030)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflicts of interest and financial disclosures, and funding and support.
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EMBARGOED FOR RELEASE: 10:30 A.M. (ET), MONDAY, AUGUST 28, 2023
Media advisory: The full study and editor’s note are linked to this news release. This study is being released to coincide with presentation at the European Society of Cardiology Congress 2023.
About The Study: The results of this randomized clinical trial show that for patients with symptomatic obstructive hypertrophic cardiomyopathy, there is sufficient and sustained improvement with mavacamten, a selective allosteric and reversible cardiac myosin inhibitor, thereby reducing the need for septal reduction therapy. Although this represents a useful therapeutic option, given the potential risk of left ventricular systolic dysfunction, there is a continued need for close monitoring.
Authors: Milind Y. Desai, M.D., M.B.A., of the Cleveland Clinic, is the corresponding author.
(doi:10.1001/jamacardio.2023.3342)
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About The Study: The findings of this systematic review and meta-analysis of 18 long-term randomized clinical trials involving 2.1 million individuals suggest that current evidence does not substantiate the claim that common cancer screening tests save lives by extending lifetime, except possibly for colorectal cancer screening with sigmoidoscopy.
Authors: Michael Bretthauer, M.D., Ph.D., of the University of Oslo in Oslo, Norway, is the corresponding author.
(doi:10.1001/jamainternmed.2023.3798)
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About The Study: In a large cohort of U.S. military veterans serving after 9/11, suicide rates increased more than 10-fold from 2006-2020, a significantly greater rate of change than in the U.S. adult population. Over the 15-year period, veterans with traumatic brain injury (TBI) had suicide rates 56% higher than veterans without TBI and three times higher than the U.S. adult population.
Authors: Jeffrey T. Howard, Ph.D., of the University of Texas at San Antonio, is the corresponding author.
(doi:10.1001/jamaneurol.2023.2893)
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About The Study: This case series found that young brain donors exposed to repetitive head impacts were highly symptomatic regardless of chronic traumatic encephalopathy (CTE) status, and the causes of symptoms in this sample are likely multifactorial. Future studies that include young brain donors unexposed to repetitive head impacts are needed to clarify the association among exposure, white matter and microvascular pathologic findings, CTE, and clinical symptoms.
Authors: Ann C. McKee, M.D., of the U.S. Department of Veteran Affairs in Boston, is the corresponding author.
(doi:10.1001/jamaneurol.2023.2907)
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this study of hospitals reporting SARS-CoV-2 infections, there was an increase of hospital-onset SARS-CoV-2 infections when community-onset infections were higher, indicating a need for ongoing and enhanced surveillance and prevention efforts to reduce in-hospital transmission of SARS-CoV-2 infections, particularly when community-incidence of SARS-CoV-2 infections is high.
Authors: Kelly M. Hatfield, M.S.P.H., of the Centers for Disease Control and Prevention in Atlanta, is the corresponding author.
(doi:10.1001/jamanetworkopen.2023.29441)
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EMBARGOED FOR RELEASE: 6:15 A.M. (ET), MONDAY, AUGUST 28, 2023
Media advisory: The full study is linked to this news release. This study is being released to coincide with presentation at the European Society of Cardiology Congress 2023.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this study of 111,000 U.S. military veterans with coronary artery disease, suboptimal lipid-lowering therapy was prevalent in the clinical setting. Optimization of statin therapy was projected to produce clinically relevant reductions in the risks of death and cardiovascular events. Despite a lesser lipid-lowering efficacy of ezetimibe, its widespread use on a population level in conjunction with optimized statin therapy may be associated with further meaningful reductions in cardiovascular risk.
Authors: Gregory G. Schwartz, M.D., Ph.D., of the Rocky Mountain Regional VA Medical Center in Aurora, Colorado, is the corresponding author.
(doi:10.1001/jamanetworkopen.2023.29066)
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EMBARGOED FOR RELEASE: 8 A.M. (ET), MONDAY, AUGUST 28, 2023
Media advisory: The full study is linked to this news release. This study is being released to coincide with presentation at the European Society of Cardiology Congress 2023.
About The Study: Muvalaplin was not associated with tolerability concerns and lowered lipoprotein(a) (Lp[a]) levels up to 65% following daily administration for 14 days in this first-in-human phase 1 study involving healthy participants. Lipoprotein(a) is associated with atherosclerotic disease and aortic stenosis. Longer and larger trials will be required to further evaluate safety, tolerability, and effect of muvalaplin on Lp(a) levels and cardiovascular outcomes.
Authors: Stephen J. Nicholls, M.B.B.S., Ph.D., of Monash University in Clayton, Victoria, Australia, is the corresponding author.
(doi:10.1001/jama.2023.16503)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
About The Study: The results of this study suggest that higher-staffed and higher-performing hospitals were more resilient to the conditions of the COVID-19 pandemic, but by late 2021, patients’ experience of care had declined in all hospitals.
Authors: Marc N. Elliott, Ph.D., of the RAND Corporation in Santa Monica, California, is the corresponding author.
(doi:10.1001/jamahealthforum.2023.2766)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: This study found that while the pandemic was associated with worse treatment and outcomes in patients with acute myocardial infarction (AMI; heart attack), race and ethnicity–associated inequities did not increase significantly. These findings suggest the need for additional efforts to mitigate outcomes associated with the COVID-19 pandemic for patients admitted with AMI when the hospital COVID-19 burden is substantially increased.
Authors: Laurent G. Glance, M.D., of the University of Rochester School of Medicine in Rochester, New York, is the corresponding author.
(doi:10.1001/jamanetworkopen.2023.30327)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About The Study: The findings of this study suggest that artificial intelligence (AI) chatbots generally produce accurate information for the top cancer-related search queries, but the responses are not readily actionable and are written at a college reading level. These limitations suggest that AI chatbots should be used supplementarily and not as a primary source for medical information.
Authors: Abdo E. Kabarriti, M.D., of the State University of New York Downstate Health Sciences University in New York, is the corresponding author.
(doi:10.1001/jamaoncol.2023.2947)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
