School-Based Health Centers, Access to Care, and Income-Based Disparities

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, SEPTEMBER 18, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this study using nationally representative survey data with difference-in-differences analysis of school-based health center (SBHC) adoption, SBHCs were associated with access to care and reduced income-based disparities. These findings support additional SBHC expansion. 

Authors: Michel Boudreaux, Ph.D., of the University of Maryland in College Park, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.34532)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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USPSTF Recommendation on Screening for Hypertensive Disorders of Pregnancy

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, SEPTEMBER 19, 2023

Media advisory: To contact the U.S. Preventive Services Task Force, email the Media Coordinator at Newsroom@USPSTF.net or call 301-951-9203. The full report and related articles are linked to this news release.

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Bottom Line: The U.S. Preventive Services Task Force (USPSTF) recommends screening for hypertensive disorders in pregnant persons with blood pressure measurements throughout pregnancy. Hypertensive disorders of pregnancy are among the leading causes of maternal morbidity and mortality in the U.S. The rate has been increasing from approximately 500 cases per 10,000 deliveries in 1993 to 1,021 cases per 10,000 deliveries in 2016 to 2017. The USPSTF routinely makes recommendations about the effectiveness of preventive care services and this recommendation is consistent with its 2017 recommendation statement.

 

(doi:10.1001/jama.2023.16991)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.

Note: More information about the U.S. Preventive Services Task Force, its process, and its recommendations can be found on the newsroom page of its website.

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Racial and Ethnic Disparities in Long-Acting Injectable Antipsychotic Use in a National Sample of Medicare Beneficiaries With Schizophrenia

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Receipt of BNT162b2 Vaccine and COVID-19 Ambulatory Visits in Young US Children

JAMA

EMBARGOED FOR RELEASE: 10 A.M. (ET), FRIDAY, SEPTEMBER 15, 2023

Media advisory: The full study is linked to this news release.

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About The Study: Receiving at least two doses of wild-type BNT162b2 vaccine (Pfizer) was associated with a reduced risk of COVID-19 emergency department or urgent care and outpatient visits in children younger than five years. The risk of SARS-CoV-2 encounters appeared lower for those with two versus three doses of BNT162b2, albeit with wide CIs, which is likely due to more immune-evasive Omicron sublineages (e.g., BQ.1-related and XBB-related strains) becoming dominant by the time young children received their third dose and longer median time since dose three compared with dose two.

Authors: Sara Y. Tartof, Ph.D., M.P.H., of the Kaiser Permanente Southern California Department of Research & Evaluation in Pasadena, is the corresponding author.

 

(doi:10.1001/jama.2023.17473)

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Cost of Public Health Insurance for US-Born and Immigrant Adults

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, SEPTEMBER 15, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: The findings of this study of 44,000 low-income, working-age adults suggest that the direct cost of providing public health insurance to immigrants is less than that for the U.S. born, and immigrants’ health care utilization, upon coverage, remains comparatively modest, thus refuting the notion that providing insurance to immigrants imposes a heavy fiscal burden. 

Authors: Felix M. Muchomba, Ph.D., of the State University of New Jersey in New Brunswick, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2023.34008)

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Premenstrual Disorders, Timing of Menopause, and Severity of Vasomotor Symptoms

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, SEPTEMBER 19, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: In this study of 3,635 female participants in the U.S., premenstrual disorders (PMDs) were associated with increased risks of early menopause and moderate or severe vasomotor symptoms (VMS). PMDs may be indicative of underlying physiology linked to early menopause and VMS, suggesting a phenotype observable during the reproductive years that may allow clinicians to target women at risk of earlier menopause and subsequent health risks later in the life course.

Authors: Yihui Yang, M.P.H., and Donghao Lu, M.D., Ph.D., of the Karolinska Institutet in Stockholm, Sweden are the corresponding authors.

 

(doi: 10.1001/jamanetworkopen.2023.34545)

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Interventions for Physical Capacity and Quality of Life in Adults With Post–COVID-19 Condition

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, SEPTEMBER 19, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: The findings of this systematic review and meta-analysis suggest that rehabilitation interventions in adults with post–COVID-19 condition are associated with improvements in functional exercise capacity, dyspnea, and quality of life, with a high probability of improvement compared with the current standard care. The certainty of evidence was moderate for functional exercise capacity and quality of life and low for other outcomes.

Authors: Dimitra V. Pouliopoulou, M.Sc., of Western University in London, Ontario, Canada, is the corresponding author.

 

(doi: 10.1001/jamanetworkopen.2023.33838)

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Temporal Association Among Influenza-Like Illness, Cardiovascular Events, and Vaccine Dose in Patients With High-Risk Cardiovascular Disease

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Remotely Delivered Cancer Genetic Testing in the Making Genetic Testing Accessible Trial

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Gender Bias and Ophthalmology Accreditation Council for Graduate Medical Education Milestones Evaluations

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Use of Physical Therapy and Subsequent Falls Among Patients With Dizziness

JAMA Otolaryngology–Head & Neck Surgery

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, SEPTEMBER 14, 2023

Media advisory: The full study is linked to this news release.

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About The Study: The findings of this study of 805,000 patients ages 18 or older suggest that receipt of physical therapy (PT) after presentation for dizziness was associated with a reduction in fall risk during the subsequent 12 months; thus, timely PT referral for dizziness may be beneficial for these patients. Future research, ideally with a clinical trial design, is needed to explore the independent impact of PT on subsequent falls for adults with dizziness. 

Authors: Meredith E. Adams, M.D., M.S., of the University of Minnesota in Minneapolis, is the corresponding author. 

 

(doi:10.1001/jamaoto.2023.2840)

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Geographical Variation in Social Determinants of Female Breast Cancer Mortality Across US Counties

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, SEPTEMBER 14, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: The results of this study of 2,176 counties suggest that breast cancer mortality in the U.S. can be affected by where individuals live, and that more comprehensive and geographically targeted interventions may lead to healthier communities. 

Authors: Taylor Anderson, Ph.D., of George Mason University in Fairfax, Virginia, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.33618)

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Dialectical Behavior Therapy for Adolescents With Bipolar Disorder

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Economic Evaluation of Extended-Release Buprenorphine for Persons With Opioid Use Disorder

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, SEPTEMBER 13, 2023

Media advisory: The full study and commentary are linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this economic evaluation of extended-release buprenorphine compared with transmucosal buprenorphine for the treatment of opioid use disorder, extended-release buprenorphine was not associated with efficient allocation of limited resources when transmucosal buprenorphine was available. Future initiatives should aim to improve retention rates or decrease costs associated with extended-release buprenorphine. 

Authors: Juliet M. Flam-Ross, B.A., of the London School of Hygiene and Tropical Medicine in London, and Sabrina A. Assoumou, M.D., M.P.H., of the Boston Medical Center in Boston, are the corresponding authors. 

 

(doi:10.1001/jamanetworkopen.2023.29583)

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Long-Term Quality of Life After Out-of-Hospital Cardiac Arrest

JAMA Cardiology

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, SEPTEMBER 13, 2023

Media advisory: The full study is linked to this news release.

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About The Study: In this survey study of 2,552 survivors of cardiac arrest in Denmark, health-related quality of life up to 20 years after the event was consistently high across follow-up periods and comparable to the general Danish population. These findings support resource allocation and efforts targeted to increasing survival after out-of-hospital cardiac arrest.

Authors: Harman Yonis, M.D., of Nordsjallands Hospital in Hillerod, Denmark, is the corresponding author.

 

(doi:10.1001/jamacardio.2023.2934)

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Aldosterone Synthase Inhibition With Lorundrostat for Uncontrolled Hypertension

JAMA

EMBARGOED FOR RELEASE: 7:30 A.M. (ET), SUNDAY, SEPTEMBER 10, 2023

Media advisory: The full study and editorial are linked to this news release. This study is being released to coincide with presentation at the AHA Hypertension Scientific Sessions 2023.

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About The Study: Among individuals with uncontrolled hypertension in this randomized clinical trial that included 200 participants, use of lorundrostat was effective at lowering blood pressure compared with placebo, which will require further confirmatory studies.

Authors: Steven E. Nissen, M.D., of the Cleveland Clinic Foundation, is the corresponding author.

 

(doi:10.1001/jama.2023.16029)

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Association of Gestational Diabetes With Subsequent Long-Term Risk of Mortality

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Use of Tenofovir Alafenamide Fumarate for HIV Pre-Exposure Prophylaxis and Incidence of Hypertension, Initiation of Statins

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, SEPTEMBER 11, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this study of people taking pre-exposure prophylaxis (PrEP) for HIV, tenofovir alafenamide fumarate (TAF) use was found to be associated with higher incident hypertension and statin initiation compared with tenofovir disoproxil fumarate use, especially in those 40 years or older. Continued monitoring of blood pressure and lipids for TAF users is warranted. 

Authors: Adovich S. Rivera, M.D., Ph.D., of Kaiser Permanente Southern California in Pasadena, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.32968)

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Racial Differences in Clinical Presentation in Individuals Diagnosed With Frontotemporal Dementia

JAMA Neurology

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, SEPTEMBER 11, 2023

Media advisory: The full study is linked to this news release.

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About The Study: The findings of this exploratory study suggest there are racial disparities in dementia severity, functional impairment, and neuropsychiatric symptoms. Future work must address racial disparities and their underlying determinants as well as the lack of representation of racially minoritized individuals in nationally representative dementia registries.

Authors: Lauren Massimo, Ph.D., of the University of Pennsylvania in Philadelphia, is the corresponding author.

 

(doi:10.1001/jamaneurol.2023.3093)

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Efficacy, Tolerability of Gefapixant for Treatment of Refractory or Unexplained Chronic Cough

JAMA

EMBARGOED FOR RELEASE: 6:30 A.M. (ET), MONDAY, SEPTEMBER 11, 2023

Media advisory: The full study and editorial are linked to this news release. This study is being released to coincide with presentation at the European Respiratory Society International Congress 2023.

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About The Study: In this dose-response meta-analysis that included nine randomized clinical trials and 2,980 patients, compared with placebo, gefapixant (45 mg orally twice daily) led to modest improvements in cough frequency, cough severity, and cough-specific quality of life but increased taste-related adverse events.

Authors: Imran Satia, M.D., Ph.D., of McMaster University in Hamilton, Ontario, Canada, is the corresponding author.

 

(doi:10.1001/jama.2023.18035)

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Sedentary Behavior and Incident Dementia Among Older Adults

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, SEPTEMBER 12, 2023

Media advisory: The full study is linked to this news release.

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About The Study: In this study of prospectively collected data of 49,000 adults age 60 or older participating in the UK Biobank, more time spent in sedentary behaviors was significantly associated with higher incidence of all-cause dementia. Future research is needed to determine whether the association between sedentary behavior and risk of dementia is causal.

Authors: David A. Raichlen, Ph.D., of the University of Southern California in Los Angeles, is the corresponding author.

 

(doi:10.1001/jama.2023.15231)

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Use of Antihypertensives, Blood Pressure, and Estimated Risk of Dementia in Late Life

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, SEPTEMBER 12, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: This meta-analysis including individual participant data from 34,000 older adults in 17 studies found that antihypertensive use was associated with decreased dementia risk compared with individuals with untreated hypertension through all ages in late life. Individuals with treated hypertension had no increased risk of dementia compared with healthy controls.

Authors: Matthew J. Lennon, M.D., of the University of New South Wales in Sydney, Australia is the corresponding author.

 

(doi: 10.1001/jamanetworkopen.2023.33353)

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Race and Ethnicity and Nonpharmacologic Care for Chronic Low Back Pain

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, SEPTEMBER 12, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: In this study of Medicare beneficiaries with comorbid chronic low back pain and opioid use disorder (OUD), receipt of physical therapy and chiropractic care was low overall and lower across most racial and ethnic minority groups compared with non-Hispanic white persons. The findings underscore the need to address inequities in guideline-concordant pain management, particularly among Black or African American and Hispanic persons with OUD.

Authors: Patience Moyo, Ph.D., of the Brown University School of Public Health in Providence, Rhode Island is the corresponding author.

 

(doi: 10.1001/jamanetworkopen.2023.33251)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Medicare Part B Spending on Macular Degeneration Treatments Associated With Manufacturer Payments to Ophthalmologists

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama-health-forum/fullarticle/10.1001/jamahealthforum.2023.2951?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=090823

About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

Spending on and Use of Clinician-Administered Drugs in Medicare

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama-health-forum/fullarticle/10.1001/jamahealthforum.2023.2941?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=090823

About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

Immunogenicity and Reactogenicity of Co-administration of COVID-19 and Influenza Vaccines

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, SEPTEMBER 8, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this study of health care workers who received a COVID-19 vaccine, an influenza vaccine, or both, co-administration was not associated with substantially inferior immune response or to more frequent adverse events compared with COVID-19 vaccine administration alone, supporting the co-administration of these vaccines. 

Authors: Gili Regev-Yochay, M.D., of the Sheba Medical Center in Ramat Gan, Israel, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.32813)

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Readmission Rates After Acute Respiratory Distress Syndrome in Children

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, SEPTEMBER 8, 2023

Media advisory: The full study and commentary are linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: The findings of this study suggest that childhood survivors of acute respiratory distress syndrome (ARDS) are at high risk of readmission in the first two months after discharge. Future studies should evaluate whether post-discharge interventions (e.g., telephonic contact, follow-up clinics, and home health care) may help reduce the readmission burden. 

Authors: Garrett Keim, M.D., of Children’s Hospital of Philadelphia, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.30774)

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Calcium Channel Blocker Use and Associated Glaucoma and Related Traits

JAMA Ophthalmology

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, SEPTEMBER 7, 2023

Media advisory: The full study and commentary are linked to this news release.

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About The Study: Calcium channel blocker use was adversely associated with glaucoma prevalence in this study of 427,000 adult UK Biobank participants, suggesting that calcium channel blockers may represent an important modifiable risk factor for glaucoma, potentially through an intraocular pressure–independent mechanism. 

Authors: Alan Kastner, M.D., M.Sc., of the Moorfields Eye Hospital National Health Service Foundation Trust and University College London Institute of Ophthalmology in London, is the corresponding author.

 

(doi:10.1001/jamaophthalmol.2023.3877)

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Early Access to Testosterone Therapy in Transgender and Gender-Diverse Adults Seeking Masculinization

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, SEPTEMBER 7, 2023

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2023.31919?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=090723

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this randomized clinical trial including 64 transgender and gender-diverse adults, immediate testosterone therapy compared with no treatment significantly reduced gender dysphoria, depression, and suicidality in transgender and gender-diverse individuals desiring testosterone therapy. 

Authors: Ada S. Cheung, M.B.B.S., Ph.D., of Austin Health in Heidelberg, Victoria, Australia, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.31919)

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Analysis of Heat Exposure During Pregnancy and Severe Maternal Morbidity

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, SEPTEMBER 7, 2023

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2023.32780?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=090723

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: Long- and short-term heat exposure during pregnancy was associated with higher risk of severe maternal morbidity in this study with 403,000 pregnancies from 2008 to 2018 in Southern California. These results might have important implications for severe maternal morbidity prevention, particularly in a changing climate. 

Authors: Jun Wu, Ph.D., of the University of California, Irvine, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.32780)

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Opioid-Free Discharge After Pancreatic Resection Through a Learning Health System Paradigm

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Changes in Health Care Costs, Survival, and Time Toxicity in the Era of Immunotherapy and Targeted Systemic Therapy for Melanoma

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Efficacy, Safety of Antidepressants in Patients With Comorbid Depression and Medical Diseases

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Incidence of In Situ and Invasive Cutaneous Melanomas During the Pandemic

JAMA Dermatology

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, SEPTEMBER 6, 2023

Media advisory: The full study is linked to this news release.

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About The Study: Researchers identified decreases of in situ and invasive melanoma diagnoses during 2020, which may reflect decreased skin cancer screening examinations or access to dermatologic care during the pandemic, both of which may lead to reduced melanoma diagnoses. This study adds to the current literature by highlighting that the relative increase in thick melanomas in 2020 was primarily associated with a marked decrease in thin melanomas, rather than an absolute increase in thicker melanomas.

Authors: Rebecca I. Hartman, M.D., M.P.H., of Brigham and Women’s Hospital in Boston, is the corresponding author.

 

(doi:10.1001/jamadermatol.2023.2712)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Cannabis-Involved Traffic Injury Emergency Department Visits After Cannabis Legalization and Commercialization

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, SEPTEMBER 6, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: This study found large increases in cannabis involvement in emergency department visits for traffic injury over time in Ontario, Canada, which may have accelerated following nonmedical cannabis commercialization. Although the frequency of visits was rare, they may reflect broader changes in cannabis-impaired driving. Greater prevention efforts, including targeted education and policy measures, in regions with legal cannabis are indicated. 

Authors: Daniel T. Myran, M.D., M.P.H., of the University of Ottawa in Ottawa, Ontario, Canada, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.31551)

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Pharmacy e-Prescription Dispensing Before and After CancelRx Implementation

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Clinician Response to Patient Medication Prices Displayed in the EHR

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Tobacco Product Marketing Orders, Online Marketing and Sale of Unauthorized Electronic Nicotine Delivery Systems Products

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Eye-Tracking–Based Measurement of Social Visual Engagement Compared With Expert Clinical Diagnosis of Autism

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, SEPTEMBER 5, 2023

Media advisory: The full study and editorial are linked to this news release.

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About The Study: In a study of children ages 16 to 30 months assessed for autism in six specialty clinics, eye-tracking–based measurement of social visual engagement was predictive of autism diagnoses by clinical experts. Further evaluation of this test’s role in early diagnosis and assessment of autism in routine specialty clinic practice is warranted.

Authors: Warren Jones, Ph.D., of Children’s Healthcare of Atlanta, is the corresponding author.

 

(doi:10.1001/jama.2023.13295)

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Measurements of Social Visual Engagement to Aid Early Diagnosis and Assessment of Autism

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, SEPTEMBER 5, 2023

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In two diagnostic studies of 1,089 children younger than age 3, objective eye-tracking–based measurements of social visual engagement quantified diagnostic status as well as individual levels of social disability, verbal ability, and nonverbal ability in autism. These findings suggest that objective measurements of social visual engagement can be used to aid in autism diagnosis and assessment. 

Authors: Warren Jones, Ph.D., of Children’s Healthcare of Atlanta, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.30145)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Cardiac Arrest Survival at EMS Agencies in Catchment Areas With Primarily Black and Hispanic Populations

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, SEPTEMBER 5, 2023

Media advisory: The full study and related article are linked to this news release.

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About The Study: Risk-standardized survival rates for out-of-hospital cardiac arrest were 1.9% lower at emergency medical service (EMS) agencies working in Black and Hispanic catchment areas than in white catchment areas in this study including 764 EMS agencies. This difference was not explained by EMS response times, rates of EMS termination of resuscitation, or first responder rates of initiating cardiopulmonary resuscitation or applying an automated external defibrillator. These findings suggest there is a need for further assessment of these discrepancies. 

Authors: Paul S. Chan, M.D., M.Sc., Saint Luke’s Hospital Mid America Heart Institute in Kansas City, is the corresponding author.

 

(doi:10.1001/jamainternmed.2023.4303)

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Trends in Preterm Infant Mortality by Race, Socioeconomic Status

JAMA Pediatrics

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, SEPTEMBER 5, 2023

Media advisory: The full study and editorial are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapediatrics/fullarticle/10.1001/jamapediatrics.2023.3487?guestAccessKey=9cd043ba-9d37-4115-916c-0c25385762a3utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=090523

 

About The Study: This study found that between 1995 and 2020, U.S. preterm infant mortality improved among all categories of prematurity. Inequalities in preterm infant mortality based on maternal race and ethnicity have remained constant while socioeconomic disparities have widened over time. 

Authors: Tim Venkatesan, M.A. (Cantab), M.B., B.Chir., D.T.M.&H., of the UCL Great Ormond Street Institute of Child Health in London, is the corresponding author.

 

(doi:10.1001/jamapediatrics.2023.3487)

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Emergency Department Pediatric Readiness and Disparities in Mortality Based on Race and Ethnicity

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, SEPTEMBER 5, 2023

Media advisory: The full study and commentary are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2023.32160?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=090523

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: In this study of 633,000 children treated in 586 emergency departments across 11 states, mortality of Black children was greater than that of white children at all quartile levels of readiness among those with acute medical emergencies but not traumatic injuries. Increased readiness was associated with decreased mortality overall, and it decreased most for Black children with acute medical emergencies. 

Authors: Peter C. Jenkins, M.D., M.Sc., of the Indiana University School of Medicine in Indianapolis, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.32160)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Volume of Care for Primary Care Physicians in Integrated vs Independent Practices Through the Pandemic

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama-health-forum/fullarticle/10.1001/jamahealthforum.2023.2883?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=090123

About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

Weighted Lottery to Equitably Allocate Scarce Supply of COVID-19 Monoclonal Antibody

JAMA Health Forum

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, SEPTEMBER 1, 2023

Media advisory: The full study and commentary are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama-health-forum/fullarticle/10.1001/jamahealthforum.2023.2774?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=090123

About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

 

About The Study: The results of this study suggest that a weighted lottery to allocate scarce resources is feasible and may result in more drug allocation to individuals who reside in disadvantaged neighborhoods and who identify as Black; however, Black individuals allocated the drug may be less likely to accept allocation and receive it. 

Authors: Erin K. McCreary, Pharm.D., of the University of Pittsburgh School of Medicine, is the corresponding author.

 

(doi:10.1001/jamahealthforum.2023.2774)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Telehealth vs In-Clinic Medication Abortion Services

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, SEPTEMBER 1, 2023

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2023.31900?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=090123

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: The findings of this study suggest that telehealth medication abortion services (tele-MAB) facilitates abortion care access for those further from brick-and mortar abortion facilities and, thus, may mitigate the impacts of travel logistics and costs. Additionally, tele-MAB may better meet the needs of those with prior abortion experience, perhaps due to greater familiarity with the abortion process. 

Authors: Anna E. Fiastro, M.P.H., M.E.M., Ph.D., of the University of Washington in Seattle, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.31900)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Ocular Symptoms in Adolescents and Young Adults With Electronic Cigarette, Cigarette, and Dual Use

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaophthalmology/fullarticle/10.1001/jamaophthalmol.2023.3852?guestAccessKey=c723dd96-47a7-4e89-8b4c-40de3ed59d9e&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=083123

Sex and Racial and Ethnic Diversity Among Ophthalmology Subspecialty Fellowship Applicants

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Deciphering Knowledge, Opinions of HPV and HPV Vaccination for Facilitation of Point-of-Care Vaccination in Adults

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaotolaryngology/fullarticle/10.1001/jamaoto.2023.2073?guestAccessKey=77946da2-b66d-4c16-a77a-22838b86a2e2&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=083123

SARS-CoV-2 Infection, Hospitalization, and Mortality in Adults With and Without Cancer

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, AUGUST 31, 2023

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2023.31617?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=083123

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: The results of this study including 11.7 million adults in Ontario, Canada, suggest that the absence of a prioritization strategy for access to critical care treatment may be a factor in significantly greater SARS-CoV-2–associated mortality in patients with cancer. 

Authors: Kelvin K.W. Chan, M.D., Ph.D., of ICES in Toronto, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2023.31617)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Single-Dose Psilocybin Treatment for Major Depressive Disorder

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, AUGUST 31, 2023

Media advisory: The full study and editorial are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2023.14530?guestAccessKey=7ff7bcd4-634a-4faa-ae0f-3ed11e9ef407&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=083123

 

About The Study: In a randomized clinical trial with 104 participants, psilocybin treatment was associated with a clinically significant sustained reduction in depressive symptoms and functional disability, without serious adverse events. These findings add to increasing evidence that psilocybin—when administered with psychological support—may hold promise as a novel intervention for major depressive disorder.

Authors: Charles L. Raison, M.D., of Usona Institute in Fitchburg, Wisconsin, is the corresponding author.

 

(doi:10.1001/jama.2023.14530)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Deaths Due to COVID-19 in Patients With Cancer During Different Waves of the Pandemic in the US

JAMA Oncology

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, AUGUST 31, 2023

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaoncology/fullarticle/10.1001/jamaoncol.2023.3066?guestAccessKey=85118918-ccbf-4525-bfd9-90914fdc12ad&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=083123

 

About The Study: The findings of this study suggest that patients with cancer had a disparate burden of COVID-19 mortality during the winter Omicron wave compared with the general U.S. population. With the emergence of new, immune-evasive SARS-CoV-2 variants, many of which are anticipated to be resistant to monoclonal antibody treatments, strategies to prevent COVID-19 transmission should remain a high priority. 

Authors: Chi-Fu Jeffrey Yang, M.D., of Massachusetts General Hospital in Boston, is the corresponding author. 

 

(doi:10.1001/jamaoncol.2023.3066)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.