About The Study: This study showed that during the Omicron-dominant period, patients with solid cancer and COVID-19 had higher mortality and hospitalization risks following COVID-19 infection versus patients without solid cancer with COVID-19, and that COVID-19 vaccination in the patients with cancer mitigated this risk.
Authors: Salomon M. Stemmer, M.D., of Beilinson Hospital in Petah Tikva, Israel, is the corresponding author.
(doi:10.1001/jamaoncol.2023.5042)
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this study of 1.3 million children from Ontario, Canada, a slightly higher risk of autism spectrum disorder was observed in children born to individuals with infertility, which appears partly mediated by certain obstetrical and neonatal factors. To optimize child neurodevelopment, strategies should further explore these other factors in individuals with infertility, even among those not receiving fertility treatment.
Authors: Maria P. Velez, M.D., Ph.D., of Queen’s University in Kingston, Ontario, Canada, is the corresponding author.
(doi:10.1001/jamanetworkopen.2023.43954)
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this systematic review and meta-analysis of 13 randomized clinical trials of app interventions with 1,470 participants, the feasibility and efficacy of mobile app interventions were supported in treating moderate and severe depression, and practical implications were also provided for developing effective app-based interventions in clinical practice.
Authors: Ji-Won Hur, Ph.D., of Korea University in Seoul, Republic of Korea, is the corresponding author.
(doi:10.1001/jamanetworkopen.2023.44120)
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: This study of 1,000 participants found that adults with low household income were less likely than adults with higher incomes to have a cardiologist involved in their care during a hospitalization for heart failure. These findings suggest that socioeconomic status may bias the care provided to patients hospitalized for heart failure.
Authors: Parag Goyal, M.D., M.Sc., of Weill Cornell Medicine in New York, is the corresponding author.
(doi:10.1001/jamanetworkopen.2023.44070)
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About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
About The Study: Among outpatient adults with mild to moderate COVID-19, treatment with fluvoxamine 100 mg twice daily for 13 days, compared with placebo, did not improve time to sustained recovery in this randomized clinical trial of 1,175 participants.
Authors: Susanna Naggie, M.D., M.H.S., of the Duke University School of Medicine in Durham, North Carolina, is the corresponding author.
(doi:10.1001/jama.2023.23363)
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this study of 155,000 births, using a causal inference framework based on target trial emulation, birth at 39 weeks’ gestation was not associated with adverse numeracy and literacy outcomes at school age compared with birth at 40 to 42 weeks.
Authors: Roxanne Hastie, Ph.D., of the University of Melbourne, is the corresponding author.
(doi:10.1001/jamanetworkopen.2023.43721)
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About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
About The Study: In this study of state laws, there was substantial heterogeneity in National Instant Criminal Background Check System (NICS) reporting requirements for mental health prohibitions for firearm possession and a lack of clarity around processes. This raises questions about the ability of NICS to be used to block firearm purchases or possession by individuals with court-identified high risk of perpetrating violence toward themselves or others.
Authors: Marian E. Betz, M.D., M.P.H., of the University of Colorado Anschutz Medical Campus School of Medicine in Aurora, is the corresponding author.
(doi:10.1001/jamahealthforum.2023.3945)
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this study of 7,000 older U.S. residents, food insecurity was associated with increased dementia risk, poorer memory function, and faster memory decline. Future studies are needed to examine whether addressing food insecurity may benefit brain health.
Authors: Aayush Khadka, Ph.D., of the University of California, San Francisco, is the corresponding author.
(doi: 10.1001/jamanetworkopen.2023.44186)
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this study of 25,000 veterans receiving dialysis, unstable housing experienced before starting dialysis was associated with increased risk of all-cause mortality, and risks increased with age. Further efforts are needed to understand the experiences of older adults with unstable housing and to estimate the scope of unstable housing among all individuals receiving dialysis.
Authors: Tessa K. Novick, M.D., M.S.W., M.H.S., of the University of Texas at Austin Dell Medical School in Austin, Texas is the corresponding author.
(doi: 10.1001/jamanetworkopen.2023.44448)
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: Pandemic-exposed children (assessment after March 11, 2020) had significantly higher problem solving and fine motor skills at 24 months of age but lower personal-social skills compared with non-exposed children in this study including data from the Ontario Birth Study. At 54 months of age, pandemic-exposed children had significantly higher vocabulary, visual memory, and overall cognitive performance compared with non-exposed children.
Authors: Mark Wade, Ph.D., C.Psych., of the University of Toronto, is the corresponding author.
(doi:10.1001/jamanetworkopen.2023.43814)
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About The Study: This study of 11,000 participants with type 2 diabetes found that food insecurity, housing insecurity, mental health concerns, and the perceived importance of practitioner concordance were associated with a lower likelihood of receiving eye care. Such findings highlight the self-reported barriers to seeking care and the importance of taking steps to promote health equity.
Authors: Sophia Y. Wang, M.D., M.S., of Stanford University in Palo Alto, California, is the corresponding author.
(doi:10.1001/jamaophthalmol.2023.5287)
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EMBARGOED FOR RELEASE: 7:49 A.M. (ET), THURSDAY, NOVEMBER 16, 2023
Media advisory: The full study and editorial are linked to this news release. This study is being released to coincide with presentation at the 2023 Danish Surgical Society Annual Meeting.
About The Study: In this study of 34,000 patients with colorectal cancer (CRC) who underwent surgery from 2004 to 2019, the risk of recurrence decreased over time, and higher disease stage was associated with shorter times from surgery to recurrence. Screening-detected CRC was associated with a lower risk of recurrence. Because the risk of recurrence was so low in selected patient groups, future research is warranted to explore risk-stratified surveillance protocols in patients with CRC.
Authors: Claus Lindbjerg Andersen, Ph.D., of Aarhus University Hospital in Aarhus, Denmark, is the corresponding author.
(doi:10.1001/jamaoncol.2023.5098)
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The findings of this study suggest that rates of completion for 4,133 diagnostic tests and referrals (colonoscopies, cardiac stress tests, and dermatology referrals) were low for all visit types but worse when ordered during telehealth visits. Failure to close diagnostic loops presents a patient safety challenge in primary care that may be of particular concern during telehealth encounters.
Authors: Maelys J. Amat, M.D., M.B.A., of Beth Israel Deaconess Medical Center in Boston, is the corresponding author.
(doi:10.1001/jamanetworkopen.2023.43417)
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About The Study: Children residing in more disadvantaged neighborhoods at birth had higher likelihood of autism spectrum disorder (ASD) diagnosis in a study that included 318,000 children with health insurance. Future research is warranted to investigate the mechanisms behind the neighborhood-related disparities in ASD diagnosis, alongside efforts to provide resources for early intervention and family support in communities with a higher likelihood of ASD.
Authors: Daniel A. Hackman, Ph.D., of the University of Southern California in Los Angeles, is the corresponding author.
(10.1001/jamapsychiatry.2023.4347)
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: This study of 139,000 respiratory hospitalizations in Canada of children younger than age 18 found a substantial decrease in severe respiratory disease resulting in hospitalizations, intensive care unit admissions, and mortality during the first two years of the pandemic compared with the three pre-pandemic years. These findings suggest that future evaluations of the effect of public health interventions aimed at reducing circulating respiratory pathogens during non-pandemic periods of increased respiratory illness may be warranted.
Authors: Eyal Cohen, M.D., M.Sc., of the Hospital for Sick Children in Toronto, is the corresponding author.
(doi:10.1001/jamanetworkopen.2023.43318)
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this study where the majority of 54,000 participants were African American with low socioeconomic status, diabetes was associated with elevated colorectal cancer (CRC) risk, suggesting that diabetes prevention and control may reduce CRC disparities. The association was attenuated for those who completed colonoscopies, highlighting how adverse effects of diabetes-related metabolic dysregulation may be disrupted by preventative screening.
Authors: Shaneda Warren Andersen, Ph.D., of the University of Wisconsin, Madison, is the corresponding author.
(doi:10.1001/jamanetworkopen.2023.43333)
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EMBARGOED FOR RELEASE: 9:45 A.M. (ET), SATURDAY, NOVEMBER 11, 2023
Media advisory: The full study and editorial are linked to this news release. This study is being released to coincide with presentation at the American Heart Association’s Scientific Sessions 2023.
About The Study: This secondary analysis of a randomized clinical trial validated a natural language processing model developed within a single healthcare system to identify heart failure hospitalizations. Further study is needed to determine whether natural language processing will improve the efficiency of future multicenter clinical trials by identifying clinical events at scale.
Authors: Scott D. Solomon, M.D., of Brigham and Women’s Hospital in Boston, is the corresponding author.
(doi:10.1001/jamacardio.2023.4859)
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EMBARGOED FOR RELEASE: 2 P.M. (ET), SUNDAY, NOVEMBER 12, 2023
Media advisory: The full study is linked to this news release. This study is being released to coincide with presentation at the American Heart Association’s Scientific Sessions 2023.
About The Study: Among patients with heart failure with mildly reduced ejection fraction or heart failure with preserved ejection fraction treated with dapagliflozin in this randomized clinical trial, an initial estimated glomerular filtration rate (eGFR) decline was frequent but not associated with subsequent risk of cardiovascular or kidney events. These data reinforce clinical guidance that sodium-glucose cotransporter-2 inhibitors should not be interrupted or discontinued in response to an initial eGFR decline.
Authors: Finnian R. Mc Causland, M.B.B.Ch., M.M.Sc., of Brigham and Women’s Hospital in Boston, is the corresponding author.
(doi:10.1001/jamacardio.2023.4664)
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EMBARGOED FOR RELEASE: 10:30 A.M. (ET), MONDAY, NOVEMBER 13, 2023
Media advisory: The full study is linked to this news release. This study is being presented at the American Heart Association’s Scientific Sessions 2023.
About The Study: Among patients discharged after hospitalization for heart failure (HF), de novo HF was associated with better clinical and patient-reported outcomes when compared with worsening chronic HF in this randomized clinical trial including 2,858 patients. Regardless of HF type, there was no significant difference between torsemide and furosemide with respect to 12-month clinical or patient-reported outcomes.
Authors: Selim R. Krim, M.D., of the Ochsner Clinic Foundation in New Orleans, is the corresponding author.
(doi:10.1001/jamacardio.2023.4776)
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EMBARGOED FOR RELEASE: 10:30 A.M. (ET), MONDAY, NOVEMBER 13, 2023
Media advisory: The full study and commentary are linked to this news release. This study is being released to coincide with presentation at the American Heart Association’s Scientific Sessions 2023.
About The Study: In this study of U.S. neighborhoods, cumulative environmental burden was associated with higher rates of cardiovascular risk factors and diseases, although absolute differences were small. The strongest associations were observed in socially vulnerable neighborhoods. Whether initiatives that address poor environmental conditions will improve cardiovascular health requires additional prospective investigations.
Authors: Rishi K. Wadhera, M.D., M.P.P., M.Phil., of the Beth Israel Deaconess Medical Center in Boston, is the corresponding author.
(doi:10.1001/jamacardio.2023.4680)
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EMBARGOED FOR RELEASE: 3:45 P.M. (ET), SATURDAY, NOVEMBER 11, 2023
Media advisory: The full study is linked to this news release. This study is being released to coincide with presentation at the American Heart Association’s Scientific Sessions 2023.
About The Study: Dietary sodium reduction significantly lowered blood pressure in the majority of middle-aged to elderly adults in this study including 213 participants. The decline in blood pressure from a high- to low-sodium diet was independent of hypertension status and antihypertensive medication use, was generally consistent across subgroups, and did not result in excess adverse events.
Authors: Deepak K. Gupta, M.D., M.S.C.I., of the Vanderbilt University Medical Center in Nashville, is the corresponding author.
(doi:10.1001/jama.2023.23651)
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EMBARGOED FOR RELEASE: 3:30 P.M. (ET), SATURDAY, NOVEMBER 11, 2023
Media advisory: The full study is linked to this news release. This study is being released to coincide with presentation at the American Heart Association’s Scientific Sessions 2023.
About The Study: Self-monitoring and physician-guided titration of antihypertensive medications was associated with lower blood pressure during the first nine months postpartum than usual postnatal outpatient care in this randomized clinical trial involving 220 participants in the United Kingdom.
Authors: Paul Leeson, Ph.D., of the University of Oxford in Oxford, United Kingdom, is the corresponding author.
(doi:10.1001/jama.2023.21523)
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About The Study: The findings of this study indicate an increase in the prevalence of breastfeeding initiation and breastfeeding duration at 12 months from 1999 to 2018 in the U.S. Temporal changes of breastfeeding duration at 12 months were more prevalent among male infants, older mothers, Mexican American and multiracial participants, and households with higher income.
Authors: Yongjun Zhang, Ph.D., M.D., of the Shanghai Jiao Tong University School of Medicine in Shanghai, is the corresponding author.
(doi:10.1001/jamapediatrics.2023.4942)
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About The Study: The data from this nationally representative survey study reveal a shift in tobacco use among young adults (ages 18-24), showing historically low cigarette use, which has positive public health significance. However, e-cigarette use is higher (14.5%) than reported previously, coinciding with the introduction of salt-based devices in 2015 to 2018. Over half of established vaping young adults never regularly smoked. Research suggests that exclusive e-cigarette users are unlikely to transition to combustible tobacco.
Authors: Benjamin A. Toll, Ph.D., of the Medical University of South Carolina in Charleston, is the corresponding author.
(doi:10.1001/jamainternmed.2023.5239)
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EMBARGOED FOR RELEASE: 3:45 P.M. (ET), SUNDAY, NOVEMBER 12, 2023
Media advisory: The full study is linked to this news release. This study is being released to coincide with presentation at the American Heart Association’s Scientific Sessions 2023.
About The Study: In this phase 1 study of 48 participants with elevated lipoprotein(a) levels, lepodisiran was well tolerated and produced dose-dependent, long-duration reductions in serum lipoprotein(a) concentrations. The findings support further study of lepodisiran, which is a short interfering RNA directed at hepatic synthesis of apolipoprotein(a), an essential component necessary for assembly of lipoprotein(a) particles.
Authors: Steven E. Nissen, M.D., of the Cleveland Clinic Center for Clinical Research in Cleveland, is the corresponding author.
(doi:10.1001/jama.2023.21835)
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EMBARGOED FOR RELEASE: 1:35 P.M. (ET), SATURDAY, NOVEMBER 11, 2023
Media advisory: The full study and editorial are linked to this news release. This study is being released to coincide with presentation at the American Heart Association’s Scientific Sessions 2023.
About The Study: This randomized clinical trial found that in patients with advanced heart failure treated with a fully magnetically levitated left ventricular assist device, avoidance of aspirin as part of an antithrombotic regimen, which includes a vitamin K antagonist, is not inferior to a regimen containing aspirin, does not increase thromboembolism risk, and is associated with a reduction in bleeding events.
Authors: Mandeep R. Mehra, M.D., M.Sc., of Brigham and Women’s Hospital and Harvard Medical School in Boston, is the corresponding author.
(doi:10.1001/jama.2023.23204)
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About The Study: This analysis finds that COVID-19 and the drug overdose epidemic were major contributors to the widening gender gap in life expectancy (nearly six years) between women and men in recent years. Men experienced higher COVID-19 death rates for likely multifactorial reasons, including higher burden of comorbidities and differences in health behaviors and socioeconomic factors, such as labor force participation, incarceration, and homelessness. Differentially worsening mortality from diabetes, heart disease, homicide, and suicide suggest that chronic metabolic disease and mental illness may also contribute.
Authors: Brandon W. Yan, M.D., M.P.H., of the University of California, San Francisco School of Medicine, is the corresponding author.
(doi:10.1001/jamainternmed.2023.6041)
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About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: Black women who reported experiences of interpersonal racism in situations involving employment, housing, and interactions with police appeared to have an increased risk of stroke, even after accounting for demographic and vascular risk factors, according to the results of this study including 48,000 Black women. These findings suggest that the high burden of racism experienced by Black U.S. women may contribute to racial disparities in stroke incidence.
Authors: Shanshan Sheehy, Sc.D., of Boston University, is the corresponding author.
(doi:10.1001/jamanetworkopen.2023.43203)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: Maternal mRNA vaccination was associated with a lower risk of Omicron SARS-CoV-2 infection among infants up to six months of age only if the vaccine was given during the antenatal period in this study of 7,292 infants in Singapore. These findings suggest that mRNA vaccination during pregnancy may be needed for lower risk of SARS-CoV-2 infection among newborns.
Authors: Orlanda Goh, M.B., B.S., M.P.H., of Singapore General Hospital in Singapore, and Chee Fu Yung, M.B.Ch.B., of KK Women’s and Children’s Hospital in Singapore, are the corresponding authors.
(doi:10.1001/jamanetworkopen.2023.42475)
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About The Study: There was a favorable evolution in smell and taste function throughout the observation period of this study, with taste dysfunction showing lower frequency and faster recovery compared with smell dysfunction in this analysis that included 88 cases and 88 controls. Recovery from smell dysfunction continued over the 3-year study period. At the 3-year study endpoint, smell dysfunction was comparable between both groups. Patients with post–COVID-19 condition exhibiting chemosensory alterations should be reassured that a recovery of smell function appears to continue over three years after initial infection.
Authors: Paolo Boscolo-Rizzo, M.D., of the University of Trieste in Trieste, Italy, is the corresponding author.
(doi:10.1001/jamaoto.2023.3603)
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About The Study: In this study including 3.5 million patients diagnosed with cancer, a significant deficit was noted in the number of cancer treatments provided in the first year of the COVID-19 pandemic in the U.S. Data indicated that this deficit in the number of cancer treatments provided was associated with decreases in the number of cancer diagnoses, not changes in treatment strategies.
Authors: Leticia M. Nogueira, Ph.D., M.P.H., of the American Cancer Society in Kennesaw, Georgia, is the corresponding author.
(doi:10.1001/jamaoncol.2023.4513)
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: Earlier onset of atrial fibrillation was associated with an elevated risk of subsequent all-cause dementia, Alzheimer disease, and vascular dementia in this study including 433,000 UK Biobank participants, highlighting the importance of monitoring cognitive function among patients with atrial fibrillation, especially those younger than 65 years at diagnosis.
Authors: Fanfan Zheng, Ph.D., of the Chinese Academy of Medical Sciences & Peking Union Medical College in Beijing, and Wuxiang Xie, Ph.D., of the Peking University First Hospital in Beijing, are the corresponding authors.
(doi:10.1001/jamanetworkopen.2023.42744)
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this study that included 3.4 million adults, co-administration of the BNT162b2 BA.4/5 bivalent mRNA COVID-19 vaccine (Pfizer-BioNTech) and seasonal influenza vaccine was associated with generally similar effectiveness in the community setting against COVID-19–related and seasonal influenza vaccine-related outcomes compared with giving each vaccine alone and may help improve uptake of both vaccines.
Authors: Leah J. McGrath, Ph.D., of Pfizer Inc., in New York, is the corresponding author.
(doi:10.1001/jamanetworkopen.2023.42151)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this study of 185 women with breast cancer, high neighborhood deprivation was associated with differences in tissue DNA methylation and gene expression among Black women. These findings suggest that continued investment in public health interventions and policy changes at the neighborhood level may help to remedy biological alterations that could make minoritized populations more susceptible to chronic diseases.
Authors: Stefan Ambs, Ph.D., of the National Cancer Institute in Bethesda, Maryland, is the corresponding author.
(doi:10.1001/jamanetworkopen.2023.41651)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, NOVEMBER 7, 2023
Media advisory: To contact the U.S. Preventive Services Task Force, email the Media Coordinator at Newsroom@USPSTF.net or call 301-951-9203. The full report and related articles are linked to this news release.
Bottom Line: The U.S. Preventive Services Task Force (USPSTF) concludes that the current evidence is insufficient to assess the balance of benefits and harms of routine screening performed by primary care clinicians for oral health conditions, including dental caries or periodontal-related disease, in adults. The USPSTF also concludes that the current evidence is insufficient to assess the balance of benefits and harms of preventive interventions performed by primary care clinicians for oral health conditions, including dental caries or periodontal-related disease, in adults. Dental caries (cavities) and periodontal disease (gum disease) are common and often untreated oral health conditions that affect eating, speaking, learning, smiling, and employment potential. Untreated oral health conditions can lead to tooth loss, irreversible tooth damage, and other serious adverse health outcomes.
(doi:10.1001/jama.2023.21409)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.
Note: More information about the U.S. Preventive Services Task Force, its process, and its recommendations can be found on the newsroom page of its website.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmediarelations@jamanetwork.org.
EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, NOVEMBER 7, 2023
Media advisory: To contact the U.S. Preventive Services Task Force, email the Media Coordinator at Newsroom@USPSTF.net or call 301-951-9203. The full report and related articles are linked to this news release.
Bottom Line: The U.S. Preventive Services Task Force (USPSTF) concludes that the current evidence is insufficient to assess the balance of benefits and harms of routine screening performed by primary care clinicians for oral health conditions, including dental caries, in children and adolescents ages 5 to 17. The USPSTF also concludes that the current evidence is insufficient to assess the balance of benefits and harms of preventive interventions performed by primary care clinicians for oral health conditions, including dental caries, in children and adolescents ages 5 to 17. Untreated oral health conditions in children can lead to serious infections and affect growth, development, and quality of life.
(doi:10.1001/jama.2023.21408)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.
Note: More information about the U.S. Preventive Services Task Force, its process, and its recommendations can be found on the newsroom page of its website.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmediarelations@jamanetwork.org.
EMBARGOED FOR RELEASE: 10:30 A.M. (ET), SATURDAY, NOVEMBER 4, 2023
Media advisory: The full study is linked to this news release. This study is being released to coincide with presentation at the American Society of Human Genetics 2023 Annual Meeting.
About The Study: The findings of this diagnostic study including 43,000 individuals undergoing hereditary cancer testing demonstrate that the ability to perform RNA sequencing concurrently with DNA sequencing represents an important advancement in germline genetic testing by improving detection of novel variants and classification of existing variants. This expands the identification of individuals with hereditary cancer predisposition and increases opportunities for personalization of therapeutics and surveillance.
Authors: Rachid Karam, M.D., Ph.D., of Ambry Genetics in Aliso Viejo, California, is the corresponding author.
(doi:10.1001/jamaoncol.2023.5586)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
About The Study: In this study of a nationally representative sample of 7,062 non-Hispanic Black or white adults, health care spending for Black adults in the U.S. was equal to or less than that of white adults, but only in areas of racial and economic equity and equitable insurance access. The results underscore the continuing need to recognize place as a contributor to race-based differences in health care spending.
Authors: Lorraine T. Dean, Sc.D., of the Johns Hopkins Bloomberg School of Public Health in Baltimore, is the corresponding author.
(doi:10.1001/jamahealthforum.2023.3798)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
