Health Care Utilization With Telemedicine and In-Person Visits in Pediatric Primary Care

Posted by Jim Michalski

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About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

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Hearing Aid Use at the Intersection of Race, Ethnicity, and Socioeconomic Status

Posted by Jim Michalski

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About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

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Disparities by Race and Urbanicity in Online Health Care Facility Reviews

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, NOVEMBER 22, 2024

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: This serial cross-sectional study observed a significant decrease in positive reviews for health care facilities post-COVID. These findings underscore a disparity in patient experience, particularly in rural areas and areas with the highest proportions of Black and white residents. 

Corresponding Author: To contact the corresponding author, Neil K. R. Sehgal, ME, email neilsehgal99@gmail.com.

 

(doi:10.1001/jamanetworkopen.2024.46890)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Racial and Ethnic Variation in Survival in Early-Onset Colorectal Cancer

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, NOVEMBER 22, 2024

Media advisory: The full study and commentary are linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this cohort study, racial and ethnic disparities in early-onset (before 50 years of age) colorectal cancer mortality were evident, with the highest burden among Native Hawaiian or Other Pacific Islander and non-Hispanic Black individuals. These results provide evidence of the role of social determinants of health in explaining these differences.

Corresponding Author: To contact the corresponding author, Maria Elena Martinez, PhD, email e8martinez@health.ucsd.edu.

 

(doi:10.1001/jamanetworkopen.2024.46820)

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Physical Activity and All-Cause Mortality by Age in 4 Multinational Megacohorts

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, NOVEMBER 21, 2024

Media advisory: The full study and commentary are linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this pooled analysis of cohort studies, the association between physical activity and mortality risk remained consistent across the adult lifespan, which contrasts with other modifiable health factors, for which associations with mortality risk diminished with age. Given these findings, the promotion of regular physical activity is essential at all stages of adult life. 

Corresponding Author: To contact the corresponding author, David Martinez-Gomez, PhD, email d.martinez@uam.es.

 

(doi:10.1001/jamanetworkopen.2024.46802)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Prenatal Diet and Infant Growth From Birth to Age 24 Months

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, NOVEMBER 21, 2024

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this cohort study, a prenatal diet that aligned with the U.S. Dietary Guidelines was associated with reduced patterns of rapid and slow infant growth, known risk factors associated with obesity. Future research should examine whether interventions to improve prenatal diet are also beneficial in improving growth trajectory in children. 

Corresponding Author: To contact the corresponding author, Monique M. Hedderson, PhD, email Monique.m.Hedderson@kp.org.

 

(doi:10.1001/jamanetworkopen.2024.45771)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Obesity Prevention at an Early Age

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, NOVEMBER 21, 2024

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About The Article: This editorial places results of the Greenlight Plus trial, recently published by JAMA, in context, including technological interventions and policies to help prevent childhood obesity.

Corresponding Author: To contact the corresponding author, Kevin G. Volpp, MD, PhD, email volpp70@wharton.upenn.edu.

 

(doi:10.1001/jama.2024.24026)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Alternative LDL Cholesterol–Lowering Strategy vs High-Intensity Statins in Atherosclerotic Cardiovascular Disease

Posted by Jim Michalski

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War Exposure and DNA Methylation in Syrian Refugee Children and Adolescents

Posted by Jim Michalski

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Short-Term and Long-Term Mortality Risk After Preterm Birth

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, NOVEMBER 20, 2024

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: The findings of this population-based matched cohort study suggest that individuals born preterm were at an increased risk of death from birth until their third and fourth decades of life, with higher risks as gestational age decreased. Some of these associations may have been partly due to underlying health determinants that affected preterm birth and mortality. These findings suggest that preterm birth should be recognized as a risk factor for mortality and could inform preventive strategies.

Corresponding Author: To contact the corresponding author, Asma M. Ahmed, PhD, MD, MPH, email asahmed@wakehealth.edu.

 

(doi:10.1001/jamanetworkopen.2024.45871)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Trends in Postpartum Depression by Race, Ethnicity, and Prepregnancy BMI

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, NOVEMBER 20, 2024

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this cross-sectional study, postpartum depression (PPD) diagnosis increased significantly across all racial and ethnic groups and body mass index (BMI) categories over the past decade. While rising PPD may reflect improved screening and diagnosis practices, the persistently high rates highlight the need to develop and implement interventions to prevent the condition while expanding efforts to mitigate the impact of PPD on maternal and child health. 

Corresponding Author: To contact the corresponding author, Darios Getahun, MD, PhD, MPH, email darios.t.getahun@kp.org.

 

(doi:10.1001/jamanetworkopen.2024.46486)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Partial Cardiac Denervation to Prevent Postoperative Atrial Fibrillation After Coronary Artery Bypass Grafting

Posted by Jim Michalski

JAMA Cardiology

EMBARGOED FOR RELEASE: 9:15 A.M. (ET), SUNDAY, NOVEMBER 17, 2024

Media advisory: The full study is linked to this news release. This study is being presented at the American Heart Association’s Scientific Sessions 2024.

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About The Study: This randomized clinical trial found that partial cardiac denervation was an effective procedure to reduce the occurrence of postoperative atrial fibrillation (POAF) after isolated coronary artery bypass grafting (CABG) without additional postoperative complications. These results suggest that partial cardiac denervation may be a good option for cardiac surgeons to consider for preventing POAF after CABG.

Corresponding Authors: To contact the corresponding authors, email Wei Feng, MD, PhD (fengwei@fuwai.com) and Wei Zhao, MD, PhD (zhaowei_fw@163.com).

 

(doi:10.1001/jamacardio.2024.4639)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflicts of interest and financial disclosures, and funding and support.

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Finerenone in Women and Men With Heart Failure With Mildly Reduced or Preserved Ejection Fraction

Posted by Jim Michalski

JAMA Cardiology

EMBARGOED FOR RELEASE: 9:20 A.M. (ET), SUNDAY, NOVEMBER 17, 2024

Media advisory: The full study and editor’s note are linked to this news release. This study is being presented at the American Heart Association’s Scientific Sessions 2024.

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About The Study: In the Finerenone Trial to Investigate Efficacy and Safety Superior to Placebo in Patients with Heart Failure (FINEARTS-HF), finerenone reduced the risk of the primary end point similarly in women and men with heart failure with mildly reduced or preserved ejection fraction. Finerenone, a nonsteroidal mineralocorticoid receptor antagonist, had similar tolerability in women and men.

Corresponding Author: To contact the corresponding author, John J. V. McMurray, MD, email john.mcmurray@glasgow.ac.uk.

 

(doi:10.1001/jamacardio.2024.4613)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflicts of interest and financial disclosures, and funding and support.

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Finerenone, Serum Potassium, and Clinical Outcomes in Heart Failure With Mildly Reduced or Preserved Ejection Fraction

Posted by Jim Michalski

JAMA Cardiology

EMBARGOED FOR RELEASE: 9:30 A.M. (ET), SUNDAY, NOVEMBER 17, 2024

Media advisory: The full study and commentary are linked to this news release. This study is being presented at the American Heart Association’s Scientific Sessions 2024.

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About The Study: In patients with heart failure with mildly reduced or preserved ejection fraction, finerenone, a nonsteroidal mineralocorticoid receptor antagonist, resulted in more frequent hyperkalemia and less frequent hypokalemia. However, with protocol-directed surveillance and dose adjustment, clinical benefit associated with finerenone relative to placebo was maintained even in those whose potassium level increased to greater than 5.5 mmol/L.

Corresponding Author: To contact the corresponding author, Scott D. Solomon, MD, email ssolomon@rics.bwh.harvard.edu.

 

(doi:10.1001/jamacardio.2024.4539)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflicts of interest and financial disclosures, and funding and support.

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Kidney Outcomes in Transthyretin Amyloid Cardiomyopathy

Posted by Jim Michalski

JAMA Cardiology

EMBARGOED FOR RELEASE: 12:50 P.M. (ET), SUNDAY, NOVEMBER 17, 2024

Media advisory: The full study is linked to this news release. This study is being presented at the American Heart Association’s Scientific Sessions 2024.

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About The Study: In this retrospective cohort study, decline in kidney function was frequent in patients with transthyretin amyloid cardiomyopathy (ATTR-CM) and was consistently associated with an increased risk of mortality, even after adjusting for established markers of worsening ATTR-CM. eGFR decline represents an independent marker of ATTR-CM disease progression that could guide treatment optimization in clinical practice. 

Corresponding Author: To contact the corresponding author, Marianna Fontana, MD, PhD, email m.fontana@ucl.ac.uk.

 

(doi:10.1001/jamacardio.2024.4578)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflicts of interest and financial disclosures, and funding and support.

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Hospitalization Following Outpatient Diagnosis of RSV in Adults

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, TUESDAY, NOVEMBER 19, 2024

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this cohort study of adults with outpatient medically attended-respiratory syncytial virus (RSV) infections from 3 large deidentified U.S. databases across 6 RSV seasons, approximately 1 in 20 adults experienced all-cause hospitalization within 28 days. The results of this study highlight the public health need for RSV prevention and treatment. 

Corresponding Author: To contact the corresponding author, Joshua T. Swan, PharmD, MPH, email swan.joshua@gmail.com.

 

(doi:10.1001/jamanetworkopen.2024.46010)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Oral Muvalaplin for Lowering of Lipoprotein(a)

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 2:52 P.M. ET, MONDAY, NOVEMBER 18, 2024

Media advisory: The full study is linked to this news release. This study is being presented at the American Heart Association’s Scientific Sessions 2024.

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About The Study: Muvalaplin, an oral small molecule lipoprotein(a) inhibitor, reduced lipoprotein(a) measured using intact lipoprotein(a) and apolipoprotein(a)-based assays and was well tolerated. The effect of muvalaplin on cardiovascular events requires further investigation. 

Corresponding Author: To contact the corresponding author, Stephen J. Nicholls, MBBS, PhD, email stephen.nicholls@monash.edu.

 

(doi:10.1001/jama.2024.24017)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Active Surveillance or Watchful Waiting for Intermediate-Risk Prostate Cancer, 2010-2020

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, NOVEMBER 20, 2024

Media advisory: The full study is linked to this news release.

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About The Study: Amid a rising trend of conservative management for prostate cancer, this study found a significant increase in initial active surveillance and watchful waiting for intermediate–risk prostate cancer between 2010 and 2020. This corresponds with evidence of favorable longer-term outcomes and improvements in staging imaging and risk stratification.

Corresponding Author: To contact the corresponding author, Michael S. Leapman, MD, MHS, email michael.leapman@yale.edu.

 

(doi:10.1001/jama.2024.20580)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Pulmonary Vein Isolation With Optimized Linear Ablation vs Pulmonary Vein Isolation Alone for Persistent AF

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 10:45 A.M. ET, MONDAY, NOVEMBER 18, 2024

Media advisory: The full study and editorial are linked to this news release. This study is being presented at the American Heart Association’s Scientific Sessions 2024.

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About The Study: Among patients with persistent atrial fibrillation, linear ablation combined with ethanol infusion of the vein of Marshall in addition to pulmonary vein isolation significantly improved freedom from atrial arrhythmias within 12 months compared with pulmonary vein isolation alone. 

Corresponding Authors: To contact the corresponding authors, email Changsheng Ma, MD, (chshma@vip.sina.com) and Chenyang Jiang, MD, (jiangchenyangmail@163.com).

 

(doi:10.1001/jama.2024.24438)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Trends in Gender, Racial, and Ethnic Representation Among US Neurology Faculty

Posted by Jim Michalski

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Next-Generation Multitarget Stool DNA vs Fecal Immunochemical Test in Colorectal Cancer Screening

Posted by Jim Michalski

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Zerlasiran—A Small-Interfering RNA Targeting Lipoprotein(a)

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 2:40 P.M. ET, MONDAY, NOVEMBER 18, 2024

Media advisory: The full study is linked to this news release. This study is being presented at the American Heart Association’s Scientific Sessions 2024.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.21957?guestAccessKey=f0dc38dc-63c0-41f5-a731-77e1e406f2ab&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=111824

 

About The Study: Zerlasiran, a small-interfering RNA targeting hepatic synthesis of apolipoprotein(a), was well-tolerated and reduced time-averaged lipoprotein(a) concentration by more than 80% during 36 weeks of treatment in patients with atherosclerotic cardiovascular disease. 

Corresponding Author: To contact the corresponding author, Steven E. Nissen, MD, email nissens@ccf.org.

 

(doi:10.1001/jama.2024.21957)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Prevalence of Cardiovascular-Kidney-Metabolic Syndrome Stages by Social Determinants of Health

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, MONDAY, NOVEMBER 18, 2024

Media advisory: The full study and commentary are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.45309?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=111824

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: The results of this study suggest a disproportionate burden of cardiovascular-kidney-metabolic syndrome by social determinants of health and sex. These findings highlight the need to address inequities in cardiovascular-kidney-metabolic syndrome through targeted interventions. 

Corresponding Author: To contact the corresponding author, Jie Guo, PhD, email jie.guo@ki.se.

 

(doi:10.1001/jamanetworkopen.2024.45309)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Semaglutide Eligibility Across All Current Indications for US Adults

Posted by Jim Michalski

JAMA Cardiology

EMBARGOED FOR RELEASE: 2:30 P.M. (ET), MONDAY, NOVEMBER 18, 2024

Media advisory: The full study is linked to this news release. This study is being presented at the American Heart Association’s Scientific Sessions 2024.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamacardiology/fullarticle/10.1001/jamacardio.2024.4657?guestAccessKey=baa342ec-8c33-4211-98eb-b1ec08d802eb&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=111824

 

About The Study: A total of nearly 137 million adults, representing more than half of all U.S. adults, are eligible for semaglutide therapy. This exceeds the number of adults eligible for statins (approximately 82 million), currently the most prescribed pharmaceuticals among U.S. adults. 

Corresponding Author: To contact the corresponding author, Dhruv S. Kazi, MD, MS, email dkazi@bidmc.harvard.edu.

 

(doi:10.1001/jamacardio.2024.4657)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflicts of interest and financial disclosures, and funding and support.

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Early Adoption of Sodium-Glucose Cotransporter-2 Inhibitor in Patients Hospitalized With Heart Failure With Mildly Reduced or Preserved Ejection Fraction

Posted by Jim Michalski

JAMA Cardiology

EMBARGOED FOR RELEASE: 11:30 A.M. (ET), MONDAY, NOVEMBER 18, 2024

Media advisory: The full study is linked to this news release. This study is being presented at the American Heart Association’s Scientific Sessions 2024.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamacardiology/fullarticle/10.1001/jamacardio.2024.4489?guestAccessKey=035fde61-fae7-4073-90da-14cd7c2a712d&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=111824

 

About The Study: In this study of discharge prescription of a sodium-glucose cotransporter-2 inhibitor (SGLT2i) among patients hospitalized for heart failure, prescription rates increased substantially within 2 years after publication of clinical trial evidence documenting benefit, although considerable variation in rates was found, highlighting the need to understand strategies used by higher prescribing centers to increase SGLT2i adoption.

Corresponding Author: To contact the corresponding author, Mohammad Abdel Jawad, MD, email abdeljawadmd@gmail.com.

 

(doi:10.1001/jamacardio.2024.4489)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflicts of interest and financial disclosures, and funding and support.

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Evaluating Performance and Agreement of Coronary Heart Disease Polygenic Risk Scores

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 2:30 P.M. ET, SATURDAY, NOVEMBER 16, 2024

Media advisory: The full study and editorial are linked to this news release. This study is being presented at the American Heart Association’s Scientific Sessions 2024.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.23784?guestAccessKey=5f0c3425-c031-4f57-8d41-a33a2be65d21&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=111624

 

About The Study: Coronary heart disease polygenic risk scores that performed similarly at the population level demonstrated highly variable individual-level estimates of risk. Recognizing that coronary heart disease polygenic risk scores may generate incongruent individual-level risk estimates, effective clinical implementation will require refined statistical methods to quantify uncertainty and new strategies to communicate this uncertainty to patients and clinicians. 

Corresponding Author: To contact the corresponding author, Scott M. Damrauer, MD, email Scott.Damrauer@pennmedicine.upenn.edu.

 

(doi:10.1001/jama.2024.23784)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Heart Failure in Zero Gravity— External Constraint and Cardiac Hemodynamics

Posted by Jim Michalski

JAMA Cardiology

EMBARGOED FOR RELEASE: 3 P.M. (ET), SATURDAY, NOVEMBER 16, 2024

Media advisory: The full study is linked to this news release. This study is being presented at the American Heart Association’s Scientific Sessions 2024.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamacardiology/fullarticle/10.1001/jamacardio.2024.4596?guestAccessKey=cc31323f-05a3-4b6b-a94e-db97024524f0&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=111624

 

About The Study: In this case series study, pulmonary artery systolic, diastolic, and mean pressures of 2 participants with obesity and heart failure with preserved ejection fraction were measured at zero gravity during parabolic flight to assess the effect of external constraint on left ventricular filling pressures. 

Corresponding Author: To contact the corresponding author, Benjamin D. Levine, MD, email benjaminlevine@texashealth.org.

 

 (doi:10.1001/jamacardio.2024.4596)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflicts of interest and financial disclosures, and funding and support.

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Interpreting Population Mean Treatment Effects in the Kansas City Cardiomyopathy Questionnaire

Posted by Jim Michalski

JAMA Cardiology

EMBARGOED FOR RELEASE: 12 P.M. (ET), FRIDAY, NOVEMBER 15, 2024

Media advisory: The full study and editor’s note are linked to this news release. This study is being presented at the AHA’s Quality of Care and Outcomes Research Early Career Investigator Abstract Award Competition.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamacardiology/fullarticle/10.1001/jamacardio.2024.4470?guestAccessKey=fe8933ab-b2a5-4564-918c-b64dc5a29686&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=111524

 

About The Study: Inferences about clinical impacts based on population-level mean treatment effects may be misleading, since even small between-group differences may reflect clinically important treatment benefits for individual patients. Results of this study suggest that clinical trials should explicitly describe the distributions of Kansas City Cardiomyopathy Questionnaire change at the patient level within treatment groups to support the clinical interpretation of their results. 

Corresponding Author: To contact the corresponding author, John Spertus, MD, MPH, email spertusj@umkc.edu.

 

(doi:10.1001/jamacardio.2024.4470)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflicts of interest and financial disclosures, and funding and support.

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Artemisinin Partial Resistance in Ugandan Children With Complicated Malaria

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 9 A.M. ET, THURSDAY, NOVEMBER 14, 2024

Media advisory: The full study and editorial are linked to this news release. This study is being presented at the American Society of Tropical Medicine and Hygiene Annual Meeting.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.22343?guestAccessKey=e1d2a9e9-6787-4bb6-8a5e-012c4e656527&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=111424

 

About The Study: This study found artemisinin partial resistance in Ugandan children with complicated malaria associated with the Pfkelch13 A675V variation and also found suboptimal 28-day efficacy of parenteral artesunate followed by oral artemether/lumefantrine therapy. 

Corresponding Author: To contact the corresponding author, Chandy C. John, MD, MS, email chjohn@iu.edu.

 

(doi:10.1001/jama.2024.22343)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Trends in Hospitalizations and Liver Transplants Associated With Alcohol-Induced Liver Disease

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, NOVEMBER 14, 2024

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.21503?guestAccessKey=4a087071-8c61-45b4-969b-687fa06537f0&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=111424

 

About The Study: This study found significant rate increases for alcohol-induced liver disease-related hospitalizations and liver transplants across sex and age groups between 2005 and 2021. Although older males had the highest absolute increases, the greatest relative increases occurred in younger individuals, particularly females.

Corresponding Author: To contact the corresponding author, Michele Molinari, MD, MSc, email molinarim@upmc.edu.

 

(doi:10.1001/jama.2024.21503)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Spinal Cord Stimulation vs Medical Management for Chronic Back and Leg Pain

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, NOVEMBER 14, 2024

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.44608?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=111424

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: This systematic review and network meta-analysis found that spinal cord stimulation therapies for treatment of chronic pain in back and/or lower extremities were associated with greater improvements in pain compared with conventional medical management. These findings highlight the potential of spinal cord stimulation therapies as an effective and valuable option in chronic pain management.

Corresponding Author: To contact the corresponding author, Konstantinos Soulanis, M.Sc., email konstantinos.soulanis@iqvia.com.

 

(doi:10.1001/jamanetworkopen.2024.44608)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Burden of RSV–Associated Hospitalizations in US Adults, October 2016 to September 2023

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, NOVEMBER 13, 2024

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.44756?guestAccessKey=d83f9e46-0b9d-4334-872c-25b398db5a43&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=111324

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this cross-sectional study of adults hospitalized with respiratory syncytial virus (RSV) before the 2023 introduction of RSV vaccines, RSV was associated with substantial burden of hospitalizations, ICU admissions, and in-hospital deaths in adults, with the highest rates occurring in adults 75 years or older. Increasing RSV vaccination of older adults has the potential to reduce associated hospitalizations and severe clinical outcomes.

Corresponding Author: To contact the corresponding author, Fiona P. Havers, MHS, MD, email fhavers@cdc.gov.

 

(doi:10.1001/jamanetworkopen.2024.44756)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Transcranial Direct Current Stimulation Combined With Repetitive Transcranial Magnetic Stimulation for Depression

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.44306?guestAccessKey=1365ef92-cd83-4567-bc70-bdb46ceeb5b7&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=111324

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Repurposing Semaglutide and Liraglutide for Alcohol Use Disorder

Posted by Jim Michalski

JAMA Psychiatry

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, NOVEMBER 13, 2024

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapsychiatry/fullarticle/10.1001/jamapsychiatry.2024.3599?guestAccessKey=4bf50b14-c77f-4a44-9a4f-0b52c5fd0f9b&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=111324

 

About The Study: Among patients with alcohol use disorder (AUD) and comorbid obesity/type 2 diabetes, the use of semaglutide and liraglutide were associated with a substantially decreased risk of hospitalization due to AUD. This risk was lower than that of officially approved AUD medications. Semaglutide and liraglutide may be effective in the treatment of AUD, and clinical trials are urgently needed to confirm these findings. 

Corresponding Author: To contact the corresponding author, Markku Lähteenvuo, MD, PhD, email markku.lahteenvuo@uef.fi.

 

(10.1001/jamapsychiatry.2024.3599)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Grief-Specific Cognitive Behavioral Therapy vs Present-Centered Therapy

Posted by Jim Michalski

JAMA Psychiatry

EMBARGOED FOR RELEASE: 6:35 A.M. (ET), WEDNESDAY, NOVEMBER 13, 2024

Media advisory: The full study is linked to this news release. This study is being presented at the European Grief Conference.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapsychiatry/fullarticle/10.1001/jamapsychiatry.2024.3409?guestAccessKey=3d185cbf-392b-4f52-b17e-2b6d449a7aa9&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=111324

 

About The Study: This randomized clinical trial demonstrates that cognitive behavioral therapy for prolonged grief was superior to present-centered therapy after treatment and at follow-up with regard to comorbid symptoms. Both treatments were shown to be effective and acceptable, showing the potential for dissemination and increasing patient choice. 

Corresponding Author: To contact the corresponding author, Rita Rosner, PhD, email rita.rosner@ku.de.

 

(10.1001/jamapsychiatry.2024.3409)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Income-Related Disparities in Mortality Among Young Adults With Type 2 Diabetes

Posted by Alexandra Marusarz

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, NOVEMBER 12, 2024

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.43918?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=111224

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: In this cohort study of 1.2 million individuals ages 20 to 79 in South Korea, the risk of mortality with low income was most prominent among individuals with type 2 diabetes ages 20 to 39. These findings highlight the need for socioeconomic support to reduce income-related health disparities in younger individuals.

Corresponding authors: To contact the corresponding authors, email Sin Gon Kim, MD, PhD (k50367@korea.ac.kr) and Nam Hoon Kim, MD, PhD (pourlife@korea.ac.kr).

 

(doi: 10.1001/jamanetworkopen.2024.43918)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Discontinuation of Glucagon-Like Peptide-1 Receptor Agonists

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, NOVEMBER 13, 2024

Media advisory: The full article is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.22284?guestAccessKey=7e4684ea-a57e-4064-8d2c-128da03442e7&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=111324

 

About The Article: This Viewpoint discusses the health benefits of glucagon-like peptide-1 receptor agonists (GLP-1 RAs); summarizes the clinical, policy, and equity implications of GLP-1 RA discontinuation; and calls for the identification and implementation of strategies to improve long-term adherence to GLP-1 RA therapy. 

Corresponding Author: To contact the corresponding author, Sadiya S. Khan, MD, MSc, email s-khan-1@northwestern.edu.

 

(doi:10.1001/jama.2024.22284)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Medical Board Discipline of Physicians for Spreading Medical Misinformation

Posted by Alexandra Marusarz

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, NOVEMBER 12, 2024

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.43893?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=111224

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: The frequency of discipline for physician-spread misinformation observed in this cross-sectional study was quite low despite increased salience and medical board warnings since the start of the COVID-19 pandemic about the dangers of physicians spreading falsehoods. These findings suggest a serious disconnect between regulatory guidance and enforcement and call into question the suitability of licensure regulation for combatting physician-spread misinformation.

Corresponding author: To contact the corresponding author, Richard S. Saver, J.D., email saver@email.unc.edu.

 

(doi: 10.1001/jamanetworkopen.2024.43893)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Overtreatment of Prostate Cancer Among Men With Limited Longevity in the Active Surveillance Era

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/10.1001/jamainternmed.2024.5994?guestAccessKey=b70e9756-4431-4899-aafc-16108a1f7194&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=111124

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Kidney Transplantation Among Presumed Undocumented Immigrants After Changes in US State Policies

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/10.1001/jamainternmed.2024.5953?guestAccessKey=e4c9ed39-7bf9-4c80-a32f-52e515f37fa9&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=111124

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Asthma and Memory Function in Children

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, MONDAY, NOVEMBER 11, 2024

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.42803?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=111124

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this cohort study, asthma was associated with memory difficulties in children, which may be more severe if asthma onset is earlier in childhood and may extend to executive function abilities. 

Corresponding Author: To contact the corresponding author, Nicholas J. Christopher-Hayes, MA, email nchristopherhayes@ucdavis.edu.

 

(doi:10.1001/jamanetworkopen.2024.42803)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Prevalence of Adverse Childhood Experiences in Child Population Samples

Posted by Jim Michalski

JAMA Pediatrics

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, NOVEMBER 11, 2024

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapediatrics/fullarticle/10.1001/jamapediatrics.2024.4385?guestAccessKey=0aac0d29-c18f-4e50-b422-ada01d665b00&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=111124

 

About The Study: In this study, adverse childhood experiences (ACEs), which include abuse, neglect, and family dysfunction, were prevalent among children with notable disparities across participant demographic characteristics and contexts. As principal antecedent threats to child and adolescent well-being that can affect later life prospects, ACEs represent a pressing global social issue. Effective early identification and prevention strategies, including targeted co-designed community interventions, can reduce the prevalence
of ACEs and mitigate their severe effects, thereby minimizing the harmful health consequences of childhood adversity in future generations.

Corresponding Author: To contact the corresponding author, Sheri Madigan, PhD, email sheri.madigan@ucalgary.ca.

 

(doi:10.1001/jamapediatrics.2024.4385)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

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Online Retailer Nonadherence to Age Verification, Shipping, and Flavor Restrictions on E-Cigarettes

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.21597?guestAccessKey=3b2cc868-20e1-4872-ba6b-46bb36993f37&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=111124

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State Divorce Laws, Reproductive Care Policies, and Pregnancy-Associated Homicide Rates

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, NOVEMBER 8, 2024

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.44199?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=110824

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this cross-sectional study of pregnancy-associated homicide rates, barriers to divorce were associated with higher homicide rates and access to reproductive health care was associated with lower homicide rates. This study highlights the association between state legislation and pregnancy-associated homicide in the U.S., which is important information for policymakers. 

Corresponding Author: To contact the corresponding author, Kaitlin M. Boyle, PhD, email kb49@mailbox.sc.edu.

 

(doi:10.1001/jamanetworkopen.2024.44199)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Catastrophic Health Expenditures for In-State and Out-of-State Abortion Care

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, NOVEMBER 8, 2024

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.44146?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=110824

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this cross-sectional study of U.S. patients seeking abortion, many individuals and their households were estimated to incur catastrophic health expenditures, particularly those traveling from out of state. The financial and psychological burdens of abortion seeking have likely worsened after the Dobbs decision, as more people need to cross state lines to reach abortion care. The findings suggest expansion of insurance coverage to ensure equitable access to abortion care, irrespective of people’s state of residence, is needed.

Corresponding Author: To contact the corresponding author, Ortal Wasser, MSW, email ow345@nyu.edu.

 

(doi:10.1001/jamanetworkopen.2024.44146)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Heat Waves and Adverse Health Events Among Dually Eligible Individuals 65 Years and Older

Posted by Jim Michalski

JAMA Health Forum

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, NOVEMBER 8, 2024

Media advisory: The full study and commentary are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama-health-forum/fullarticle/10.1001/jamahealthforum.2024.3884?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=110824

About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

 

About The Study: In this time-series study, heat waves were associated with increased adverse health events among dually eligible individuals 65 years and older. Without adaptation strategies to address the health-related impacts of heat, dually eligible individuals are increasingly likely to face adverse outcomes. 

Corresponding Author: To contact the corresponding author, Hyunjee Kim, PhD, email kihy@ohsu.edu.

 

(doi:10.1001/jamahealthforum.2024.3884)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Neurodevelopment in the First 2 Years of Life Following Prenatal Exposure to Maternal SARS-CoV-2 Infection

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, NOVEMBER 7, 2024

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.43697?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=110724

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this longitudinal cohort study of multiple aspects of child neurodevelopment between ages 6 and 24 months, negligible associations between prenatal exposure to SARS-CoV-2 infection and child outcomes were observed. Follow-up research is warranted to determine whether these predominantly null effects persist into later childhood.

Corresponding Author: To contact the corresponding author, Gerald F. Giesbrecht, PhD, email ggiesbre@ucalgary.ca.

 

(doi:10.1001/jamanetworkopen.2024.43697)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Racial Disparities in Genetic Detection Rates for Inherited Retinal Diseases

Posted by Jim Michalski

JAMA Ophthalmology

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, NOVEMBER 7, 2024

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaophthalmology/fullarticle/10.1001/jamaophthalmol.2024.4696?guestAccessKey=9f18f36f-3b0d-4b0e-9fa5-55edea1f9afc&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=110724

 

About The Study: Results from this study highlight a lower genetic detection rate for Black patients than for white patients with inherited retinal diseases. This supports a concern that the current development of inherited retinal disease therapeutics is highly dependent on the ability to identify the genetic cause of disease.

Corresponding Author: To contact the corresponding author, K. Thiran Jayasundera, M.D., email thiran@med.umich.edu.

 

(doi:10.1001/jamaophthalmol.2024.4696)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Long-Term Adverse Effects and Complications After Prostate Cancer Treatment

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaoncology/fullarticle/10.1001/jamaoncol.2024.4397?guestAccessKey=13ba5074-e095-494d-bf0f-6891098e9a69&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=110724

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Industry Payments to Physicians by Competing Manufacturers Within Novel Therapeutic Classes

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.20842?guestAccessKey=9d5a3ef6-4680-4bf2-9bfe-536b21ce9aed&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=110724

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Psychosis Spectrum Symptoms Before and After Adolescent Cannabis Use Initiation

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapsychiatry/fullarticle/10.1001/jamapsychiatry.2024.3525?guestAccessKey=093e49cd-cd51-4e17-8db5-7bcddccd710c&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=110624

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Neuroinflammation, Stress-Related Suicidal Ideation, and Negative Mood in Depression

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapsychiatry/fullarticle/10.1001/jamapsychiatry.2024.3543?guestAccessKey=3aa4acf9-db5b-43a7-a354-5ebf7bffc0eb&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=110624

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Racial and Ethnic Disparities in Fentanyl and Polysubstance Overdose Deaths

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapsychiatry/fullarticle/10.1001/jamapsychiatry.2024.3435?guestAccessKey=1306dc3e-ecfc-4096-a2ca-8df80c6583df&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=110624

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Long-Term Risk of Autoimmune and Autoinflammatory Connective Tissue Disorders Following COVID-19

Posted by Jim Michalski

JAMA Dermatology

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, NOVEMBER 6, 2024

Media advisory: The full study and editorial are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamadermatology/fullarticle/10.1001/jamadermatol.2024.4233?guestAccessKey=c58e0ba8-9aa0-457e-a4e7-c043439b3e52&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=110624

 

About The Study: This retrospective cohort study with an extended follow-up period found associations between COVID-19 and the long-term risk of various autoimmune and autoinflammatory connective tissue disorders. Long-term monitoring and care of patients is crucial after COVID-19, considering demographic factors, disease severity, and vaccination status, to mitigate these risks.

Corresponding Author: To contact the corresponding author, Solam Lee, MD, PhD, email solam@yonsei.ac.kr.

 

(doi:10.1001/jamadermatol.2024.4233)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Safety of Simultaneous vs Sequential mRNA COVID-19 and Inactivated Influenza Vaccines

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, NOVEMBER 6, 2024

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.43166?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=110624

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this randomized clinical trial assessing simultaneous vs sequential administration of mRNA COVID-19 and inactivated influenza vaccines, reactogenicity was comparable in both groups. These findings support the option of simultaneous administration of these vaccines. 

Corresponding Author: To contact the corresponding author, Emmanuel B. Walter, MD, MPH, email chip.walter@duke.edu.

 

(doi:10.1001/jamanetworkopen.2024.43166)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Global Disparities of Cancer and Its Projected Burden in 2050

Posted by Alexandra Marusarz

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, NOVEMBER 5, 2024

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.43198?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=110524

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: In this cross-sectional study based on data from 2022, cancer disparities were evident across Human Development Index, geographic regions, age, and sex, with further widening projected by 2050. These findings suggest that strengthening access to and quality of health care, including universal health insurance coverage, is key to providing evidence-based cancer prevention, diagnostics, and care.

Corresponding author: To contact the corresponding author, Habtamu Mellie Bizuayehu, Ph.D., M.P.H., email hmba2003@gmail.com.

 

(doi: 10.1001/jamanetworkopen.2024.43198)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Nurse Burnout and Patient Safety, Satisfaction, and Quality of Care

Posted by Alexandra Marusarz

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, NOVEMBER 5, 2024

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.43059?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=110524

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

About The Study: Nurse burnout was found to be associated with lower health care quality and safety and lower patient satisfaction in this systematic review and meta-analysis. This association was consistent across nurse and study characteristics.

Corresponding author: To contact the corresponding author, Peilin Yang, B.S., email peilin.yang@upf.edu.

 

(doi: 10.1001/jamanetworkopen.2024.43059)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Screen Time Before 2 Years of Age and Risk of Autism at 12 Years of Age

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapediatrics/fullarticle/10.1001/jamapediatrics.2024.4432?guestAccessKey=0ac3f988-c80c-43a8-af54-57fb34043c1a&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=110424

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A Digital Health Behavior Intervention to Prevent Childhood Obesity

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 5:30 P.M. ET, SUNDAY, NOVEMBER 3, 2024

Media advisory: The full study is linked to this news release. This study is being presented at the Obesity Society Conference, ObesityWeek.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.22362?guestAccessKey=718ecc07-ada5-431f-a301-60824022ecfb&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=110324

 

About The Study: A health literacy-informed digital intervention improved child weight-for-length trajectory across the first 24 months of life and reduced childhood obesity at 24 months. The intervention was effective in a racially and ethnically diverse population that included groups at elevated risk for childhood obesity. 

Corresponding Author: To contact the corresponding author, William J. Heerman, MD, MPH, email Bill.Heerman@vumc.org.

 

(doi:10.1001/jama.2024.22362)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

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Translational Science Reviews—A New JAMA Review

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 11 A.M. ET, MONDAY, NOVEMBER 4, 2024

Media advisory: The editor’s note is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.21146?guestAccessKey=8b03f724-5d87-4716-9d6f-34e5350d8472&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=110424

 

About The Article: To help clinicians keep up with ongoing basic and translational science discoveries that affect the diagnosis and treatment of human disease, JAMA has launched a new series, “Translational Science Reviews.” These new article types are succinct and informative summaries of important basic science advances that are transforming diagnosis and treatment of human disease. 

Corresponding Author: To contact the corresponding author, Mary M. McDermott, MD, email mdm608@northwestern.edu.

 

(doi:10.1001/jama.2024.21146)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

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Hospital COVID-19 Burden and Adverse Event Rates

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, MONDAY, NOVEMBER 4, 2024

Media advisory: The full study and commentary are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.42936?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=110424

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this cohort study of hospital admissions among Medicare patients during the COVID-19 pandemic, greater hospital COVID-19 burden was associated with an increased risk of in-hospital adverse effects among both patients with and without COVID-19. These results illustrate the need for greater hospital resilience and surge capacity to prevent declines in patient safety during surges in demand. 

Corresponding Author: To contact the corresponding author, Mark L. Metersky, MD, email metersky@uchc.edu.

 

(doi:10.1001/jamanetworkopen.2024.42936)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Cannabis Use During Early Pregnancy Following Recreational Cannabis Legalization

Posted by Jim Michalski

JAMA Health Forum

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, NOVEMBER 1, 2024

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama-health-forum/fullarticle/10.1001/jamahealthforum.2024.3656?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=110124

About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

 

About The Study: In this time-series study, recreational cannabis legalization implementation in California was associated with an increase in rates of cannabis use during early pregnancy, defined by both self-report and toxicology testing, driven by individuals living in jurisdictions that allowed adult-use retailers.

Corresponding Author: To contact the corresponding author, Kelly C. Young-Wolff, PhD, MPH, email kelly.c.young-wolff@kp.org.

 

(doi:10.1001/jamahealthforum.2024.3656)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Smoking Cessation and Incident Cardiovascular Disease

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, NOVEMBER 1, 2024

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.42639?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=110124

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this cohort study, smoking and cardiovascular disease (CVD) risk exhibited a dose-dependent association, with light ex-smokers having a CVD risk similar to that of never-smokers relatively soon after smoking cessation. For heavy ex-smokers, greater than 25 years might be required for the residual CVD risk to align with that of never-smokers. 

Corresponding Author: To contact the corresponding author, Seung Yong Shin, MD, PhD, email theshin04@korea.ac.kr.

 

(doi:10.1001/jamanetworkopen.2024.42639)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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