About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this longitudinal observational cohort study, gender-affirming hormone therapy was associated with lower rates of moderate-to-severe depressive symptoms, highlighting the importance of gender-affirming primary care models for transgender, nonbinary, and gender diverse patients.
Corresponding Author: To contact the corresponding author, Sari L. Reisner, ScD, MA, email sreisner@umich.edu.
(doi:10.1001/jamanetworkopen.2025.0955)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About The Study: This cohort study found that statin use was associated with a reduced risk of hepatocellular carcinoma and hepatic decompensation in patients with chronic liver disease. These findings provide support for the potential role of statins in prevention of hepatocellular carcinoma and liver disease progression.
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this survey of adults with firearm access, defensive gun use (DGU) was rare relative to gun violence exposure. Perceived threats may not necessitate DGU, and given the association between DGU and gun violence exposure, the consequences of DGU may be substantial. Narratives centering DGU as a consideration in firearm policies may misstate the risk profile of firearm access.
Corresponding Author: To contact the corresponding author, Michael D. Anestis, PhD, email mda141@sph.rutgers.edu.
(doi:10.1001/jamanetworkopen.2025.0807)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
About The Study: This economic evaluation found that although tirzepatide and semaglutide offered substantial long-term health benefits, they were not cost-effective at current net prices. Efforts to reduce the net prices of new anti-obesity medications are essential to ensure equitable access to highly effective anti-obesity medications.
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this cross-sectional study of area deprivation, vaccination access, and human papillomavirus (HPV) vaccination status in Osaka City, Japan, higher socioeconomic status and higher medical facility access were associated with higher cumulative HPV vaccination uptake. These findings suggest that further strategies, including a socioecologic approach, are needed to increase HPV vaccination and reduce disparities in uptake.
Corresponding Author: To contact the corresponding author, Yuri Ito, PhD, email yuri.ito@ompu.ac.jp.
(doi:10.1001/jamanetworkopen.2025.0747)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About The Study: High sugar-sweetened beverage intake was associated with a significantly increased risk of oral cavity cancer in women, regardless of smoking or drinking habits, yet with low baseline risk in this study. Additional studies are needed in larger cohorts, including males, to validate the impact of these findings.
Corresponding Author: To contact the corresponding author, Brittany Barber, MD, MSc, email bbarber1@uw.edu.
(doi:10.1001/jamaoto.2024.5252)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: This cohort study found that healthier diets and lower waist to hip ratio throughout midlife were associated with better brain and cognitive health in older age. The findings suggest that interventions to improve diet and manage central obesity might be most effective between ages 48 and 70.
Corresponding Author: To contact the corresponding author, Daria E. A. Jensen, DPhil, email jensen@cbs.mpg.de.
(doi:10.1001/jamanetworkopen.2025.0171)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About The Study: In this prospective cohort study among participants in the Coronary Artery Risk Development in Young Adults (CARDIA) study, food insecurity was associated with incident cardiovascular disease (CVD) even after adjustment for socioeconomic factors, suggesting that food insecurity may be an important social deprivation measure in clinical assessment of CVD risk. Whether interventions to reduce food insecurity programs can potentially alleviate CVD should be further studied.
Corresponding Author: To contact the corresponding author, Jenny Jia, MD, MSc, email jenny.jia@northwestern.edu.
(doi:10.1001/jamacardio.2025.0109)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflicts of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this survey study, participants expressed a mild preference for messages written by artificial intelligence (AI) but had a slightly decreased satisfaction when told AI was involved. Patient experience must be considered along with ethical implementation of AI. Although AI disclosure may slightly reduce satisfaction, disclosure should be maintained to uphold patient autonomy and empowerment.
Corresponding Author: To contact the corresponding author, Anand Chowdhury, MD, MMCi, email anand.chowdhury@duke.edu.
(doi:10.1001/jamanetworkopen.2025.0449)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The findings of this study suggest that promoting cardiovascular health in older adults may help alleviate the burden of neurodegenerative diseases, particularly among Black adults, who are known to experience a higher prevalence of cardiovascular disease.
Corresponding Author: To contact the corresponding author, Anisa Dhana, MD, MSc, email anisa_dhana@rush.edu.
(doi:10.1001/jamanetworkopen.2025.0527)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About The Study: An early-life responsive parenting intervention resulted in lower body mass index from age 3 to 9 compared with a control intervention. This group difference was driven by effects on female participants, with differences appearing to dissipate over time. A life-course approach may be required to sustain the benefits of early-life responsive parenting interventions for obesity prevention.
Corresponding Author: To contact the corresponding author, Ian M. Paul, MD, MSc, email ipaul@psu.edu.
(doi:10.1001/jamapediatrics.2024.6897)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About The Study: The COVID-19 pandemic was associated with varying developmental health outcomes in kindergarteners. Negative developmental trends existed immediately before the pandemic, with most persisting or slowing post-pandemic onset. These results highlight troubling trends in kindergarteners’ development, both before and during the pandemic, and more information is needed to understand why developmental outcomes are worsening over time.
Corresponding Author: To contact the corresponding author, Judith L. Perrigo, PhD, LCSW, email jperrigo@luskin.ucla.edu.
(doi:10.1001/jamapediatrics.2024.7057)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About The Study: While practitioner supply increased overall, the Dobbs decision was associated with moderate but significant relative decreases in obstetrics and gynecology practitioners in the most restrictive vs control states. Findings provide early confirmation of reports that clinicians have migrated from states most impacted by the Dobbs decision. Clinician migration has implications for reproductive care access, quality, and equity as abortion rights are increasingly decided at the state level.
Corresponding Author: To contact the corresponding author, Jane M. Zhu, MD, MPP, email zhujan@ohsu.edu.
(doi:10.1001/jamainternmed.2024.8149)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
EMBARGOED FOR RELEASE: 10:30 A.M. (ET), TUESDAY, MARCH 11, 2025
Media advisory: To contact the U.S. Preventive Services Task Force, email the Media Coordinator at Newsroom@USPSTF.net or call 301-951-9203. The full report and related articles are linked to this news release.
Bottom Line: The U.S. Preventive Services Task Force (USPSTF) concludes that the current evidence is insufficient to assess the balance of benefits and harms of screening for food insecurity on health outcomes in the primary care setting. According to survey data, 12.8% of households experienced food insecurity in 2022, with 7.7% of households experiencing low food security and 5.1% experiencing very low food security. Nearly one-third of households with incomes below the federal poverty threshold are food insecure. Food insecurity is one among a multitude of medical, psychological, and social conditions common among economically disadvantaged households. The USPSTF routinely makes recommendations about the effectiveness of preventive care services. This is a new USPSTF topic.
(doi:10.1001/jama.2025.0879)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.
Note: More information about the U.S. Preventive Services Task Force, its process, and its recommendations can be found on the newsroom page of its website.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmediarelations@jamanetwork.org.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The findings from this survey study of U.S. adults underscore the extensive and often overlooked regular exposure to mass shootings in this country. The demographic disparities in exposure highlight the need for targeted interventions and support for the most affected groups, particularly younger generations and males. Understanding these patterns is essential for addressing the broader impacts of gun violence on public health and community well-being.
Corresponding Author: To contact the corresponding author, David C. Pyrooz, PhD, email david.pyrooz@colorado.edu.
(doi:10.1001/jamanetworkopen.2025.0283)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this systematic review and meta-analysis of depression and anxiety among individuals with chronic pain, approximately 40% of adults had clinically significant depression and anxiety. Women, younger people, and people with nociplastic pain were most likely to have depression and anxiety. The co-occurrence of chronic pain with depression and anxiety is a significant public health concern necessitating routine screening in clinical settings, equitable access to specialty care, and innovative treatment development.
Corresponding Author: To contact the corresponding author, Rachel V. Aaron, PhD, email raaron4@jhmi.edu.
(doi:10.1001/jamanetworkopen.2025.0268)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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EMBARGOED FOR RELEASE: 4 P.M. (ET), THURSDAY, MARCH 6, 2025
Media advisory: The full study and commentary are linked to this news release. This study is being presented at the American Heart Association EPI/Lifestyle Scientific Sessions 2025.
About The Study: Higher intake of butter was associated with increased mortality, while higher plant-based oils intake was associated with lower mortality in this cohort study. Substituting butter with plant-based oils may confer substantial benefits for preventing premature deaths.
Corresponding Author: To contact the corresponding author, Dong D. Wang, MD, ScD, email dow471@mail.harvard.edu.
(doi:10.1001/jamainternmed.2025.0205)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: Reported intentional weight loss efforts that were coupled with measured waist circumference reductions were associated with lower risk of all-cause, cancer, and cardiovascular mortality in this cohort study. Attention to diet and exercise that promote reductions in central adiposity should be encouraged.
Corresponding Author: To contact the corresponding author, Michael Hendryx, PhD, email hendryx@iu.edu.
(doi:10.1001/jamanetworkopen.2025.0609)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About The Study: In a program using long-acting-antiretroviral therapy (LA-ART) for people with HIV, this study found that viral suppression with use of LA-ART at 48 weeks was high and did not differ among individuals starting LA-ART with or without viremia. The low CD4+ cell counts among those with viremia confirms this population was at high risk of continued disease progression.
Corresponding Author: To contact the corresponding author, Monica Gandhi, MD, MPH, email monica.gandhi@ucsf.edu.
(doi:10.1001/jama.2025.0109)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The findings of this cohort study suggest that glucagon-like peptide–1 receptor agonists (GLP-1RAs) are associated with reduced risk of developing several hematologic cancers, particularly myelodysplastic syndrome and myeloproliferative neoplasm, in patients with type 2 diabetes. This reduction in risk may be mediated by weight loss, the immunomodulatory properties of GLP-1RAs, or both.
Corresponding Author: To contact the corresponding author, Abhay Singh, MD, MPH, email singha21@ccf.org.
(doi:10.1001/jamanetworkopen.2025.0802)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this cohort study of middle-aged and older participants, persistent inadequate sleep duration and late sleep onset, whether alone or in combination, were associated with greater glycemic variability. These findings emphasize the importance of considering both sleep duration and timing for optimizing glycemic control in the general population.
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About The Study: This study found that over time, the trajectory of sports gambling frequency was associated with the trajectory of alcohol-related problems. Screening and treatment interventions are recommended for sport gamblers who also drink concurrently, especially because this group appears to be at an elevated risk for developing greater alcohol-related problems over time.
Corresponding Author: To contact the corresponding author, Joshua B. Grubbs, PhD, email joshuagrubbs12@unm.edu
(10.1001/jamapsychiatry.2025.0024)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About The Study: In 2023, reported breast and colorectal cancer screening rebounded from COVID-19 pandemic–related declines and surpassed pre-pandemic estimates. These findings are encouraging given larger-than-expected declines in early-stage breast and colorectal cancer diagnoses in 2020 and increases in distant-stage breast cancer diagnoses through 2021. Cervical cancer screening rates remained below pre-pandemic levels, a troubling trend as early-stage diagnoses continued to decrease in 2021. The persistent decline may in part reflect longer-term declines in patient knowledge and clinician recommendation of cervical cancer screening.
Corresponding Author: To contact the corresponding author, Jessica Star, MA, MPH, email Jessica.star@cancer.org.
(doi:10.1001/jama.2025.0902)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About The Study: The combination of coronary artery calcium (CAC) score with a primary prevention strategy in intermediate-risk patients with a family history of coronary artery disease was associated with reduction of atherogenic lipids and slower plaque progression compared with usual care. These data support the use of CAC score to assist intensive preventive strategies in intermediate-risk patients.
Corresponding Author: To contact the corresponding author, Thomas H. Marwick, MBBS, PhD, MPH, email Tom.Marwick@bakeridi.edu.au.
(doi:10.1001/jama.2025.0584)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: This cohort study found no significant association between the preoperative use of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and short-term postoperative aspiration pneumonia despite growing concerns about the adverse effects of these medications after surgery. This finding suggests that it may be beneficial to reassess the preoperative withholding guidelines for GLP-1 RAs.
Corresponding author: To contact the corresponding author, Eric L. Smith, M.D., email esmith@nebh.org.
(doi: 10.1001/jamanetworkopen.2025.0081)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The findings of this study suggest that higher perceived discrimination in health care settings is positively associated with delaying health care due to nervousness about seeing a health care professional. The largest mediation proportion observed was among younger adults and racial and ethnic minority groups. By prioritizing better patient-clinician communication, health care delays associated with patient apprehension related to perceived discrimination may be reduced.
Corresponding author: To contact the corresponding author, Maryam Jafari Bidgoli, Ph.D., email mjafaribidgoli@ua.edu.
(doi: 10.1001/jamanetworkopen.2025.0046)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this retrospective multi-institutional study, patients who underwent surgery immediately preceding the weekend had a significantly increased risk of complications, readmissions, and mortality compared with those treated after the weekend. Further study is needed to understand differences in care that may underpin these observations and ensure that patients receive high-quality care regardless of the day of the week.
Corresponding author: To contact the corresponding author, Raj Satkunasivam, M.D., M.S., email raj.satkunasivam@gmail.com.
(doi: 10.1001/jamanetworkopen.2024.58794)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About The Study: In this evaluation of a place-based, coordinated, countywide intervention, reports of both substantiated and unsubstantiated child sexual abuse were shown to be significantly reduced at the population level.
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: This cross-sectional study found a recent increase in cervical cancer incidence in rural U.S. counties, specifically among white women. In addition, incidence was 25% higher and mortality was 42% higher in rural vs urban counties in recent years. The increase in incidence and mortality in rural U.S. counties may reflect lower screening coverage and lower utilization of diagnostic and therapeutic care, likely resulting from heightened access barriers experienced in rural areas. Additionally, if unaddressed, lower human papillomavirus (HPV) vaccine uptake in rural areas may contribute to further widening disparities in the future.
Corresponding Author: To contact the corresponding author, Trisha L. Amboree, PhD, MPH, email amboree@musc.edu.
(doi:10.1001/jamanetworkopen.2024.62634)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: A proposed U.S. Drug Enforcement Administration rule could impede buprenorphine initiation for a substantial number of patients with opioid use disorder. In this study, more than 4,500 tele-buprenorphine initiations from 2020 to 2022—20% of tele-initiations overall—would have been prohibited under requirements for an in-person visit with the tele-initiating clinician prior to or within 30 days after tele-initiation.
Corresponding Author: To contact the corresponding author, Emma E. McGinty, PhD, email emm4010@med.cornell.edu.
(doi:10.1001/jamanetworkopen.2025.0001)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: During the COVID-19 pandemic, food insecurity decreased among Supplemental Nutrition Assistance Program (SNAP) participants in most racial and ethnic groups but did not decrease among non-SNAP participants in any group. These results suggest that during the pandemic, increased SNAP benefit amounts were associated with ameliorating food insecurity for many U.S. adults who were able to access SNAP but did not reduce racial and ethnic disparities in food insecurity.
Corresponding Author: To contact the corresponding author, Yingfei Wu, MD, MPH, email yingfeiwu322@gmail.com.
(doi:10.1001/jamanetworkopen.2024.62277)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.
About The Study: In this study, differences in out-of-pocket maternity spending among the commercially insured were associated with differences in coinsurance rates. These costs could lead people to forgo needed health care or other basic needs that support health (e.g., food or housing). Changes to health plan benefit design could improve equity in out-of-pocket maternity spending and its consequences.
Corresponding Author: To contact the corresponding author, Anna D. Sinaiko, PhD, MPP, email asinaiko@hsph.harvard.edu.
(doi:10.1001/jamahealthforum.2024.5565)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About The Study: This study found that the prevalence of adults with diabetes did not significantly change between 2013 and 2023, but glycemic control among those with diagnosed disease worsened in 2021-2023 after nearly a decade of stability. This trend was most pronounced among young adults. The increase of 1% in mean HbA1c levels and 20% decrease in glycemic control would increase the lifetime risk of cardiovascular events. Potential explanations for these findings include increased sedentary behavior, reduced social support, heightened mental health stressors, and limited access to health care and medications during the pandemic.
Corresponding Author: To contact the corresponding author, Rishi K. Wadhera, MD, MPP, MPhil, email rwadhera@bidmc.harvard.edu.
(doi:10.1001/jama.2024.28513)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this cohort study of 46,000 U.S. residents, nearly two-thirds of participants had suboptimal 5-year sleep duration trajectories. Suboptimal sleep duration trajectories were associated with as much as a 29% increase in risk of all-cause mortality. These findings highlight the importance of maintaining healthy sleep duration over time to reduce mortality risk.
Corresponding Author: To contact the corresponding author, Kelsie M. Full, PhD, MPH, email k.full@vumc.org.
(doi:10.1001/jamanetworkopen.2024.62117)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this cross-sectional study of U.S. homicide rates, substantial variation was found across and within county, race and ethnicity, sex, and age groups; American Indian and Alaska Native and Black males ages 15 to 44 had the highest rates of homicide. The findings highlight several populations and places where homicide rates were high, but awareness and violence prevention remains limited.
Corresponding Author: To contact the corresponding author, Paula D. Strassle, PhD, MSPH, email pdstrass@umd.edu.
(doi:10.1001/jamanetworkopen.2024.62069)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this cross-sectional study of social media posts about 5 popular medical tests, most posts were misleading or failed to mention important harms, including overdiagnosis or overuse. These data demonstrate a need for stronger regulation of misleading medical information on social media.
Corresponding Author: To contact the corresponding author, Brooke Nickel, PhD, email brooke.nickel@sydney.edu.au.
(doi:10.1001/jamanetworkopen.2024.61940)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: In this study, confidence in organizations to use health data responsibly was largely unchanged from 2020 to 2022, but polarization increased between politically liberal and conservative respondents. Compared with 2020, in 2022 liberal respondents reported increased confidence in the federal government to use digital health data responsibly, while conservative respondents reported decreased confidence in the federal government and agencies. Changes in confidence may be related to the prominence of these agencies (CDC, NIH) during the COVID-19 pandemic, a 2020 national election with a change in the governing political party, and political polarization.
Corresponding Author: To contact the corresponding author, Ravi Gupta, MD, MSHP, email ravigupta@jhmi.edu.
(doi:10.1001/jamanetworkopen.2024.61907)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About The Study: The findings of this study show a higher incidence of suicide for U.S. female physicians compared to female non-physicians. Comprehensive and multimodal suicide prevention strategies remain warranted.
Corresponding Author: To contact the corresponding author, Hirsh Makhija, MS, email himakhij@ucsd.edu.
(10.1001/jamapsychiatry.2024.4816)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About The Article: In May 2024, the American Law Institute approved its first-ever restatement of the law of medical malpractice, including new standards for resolving malpractice claims. This article describes the new legal standards and their significance for health professionals and organizations in 3 core areas: clinical care, communicating with patients, and the practice environment.
Corresponding Author: To contact the corresponding author, Christopher T. Robertson, JD, PhD, email ctr00@bu.edu.
(doi:10.1001/jama.2025.0097)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The findings of this study indicate that higher adherence to the Mediterranean diet is associated with a modest reduction in the risk of obesity-related cancers, independent of adiposity measures. Further research is needed to clarify the mechanisms by which the Mediterranean diet may contribute to cancer prevention.
Corresponding Author: To contact the corresponding author, Inmaculada Aguilera-Buenosvinos, PhD, email iaguilerabuenosvinos@gmail.com.
(doi:10.1001/jamanetworkopen.2024.61031)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About The Study: In this cohort study, telemedicine adoption was associated with modestly lower use of 7 of 20 examined low-value tests (most point-of-care) and no changes in use of other low-value tests, despite a small rise in total visits that might offer more testing opportunities. Results suggest possible benefits of telemedicine and mitigate concerns about telemedicine contributing to increased spending.
Corresponding Author: To contact the corresponding author, Ishani Ganguli, MD, MPH, email iganguli@bwh.harvard.edu.
(doi:10.1001/jamainternmed.2024.8354)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About The Study: The results of this cross-sectional study suggest that although physicians and most health care workers experienced lower mortality rates compared with the general population, this benefit did not fully extend to female individuals or racial and ethnic minority groups. Renewed efforts are needed to address health inequities within the health care workforce.
Corresponding Author: To contact the corresponding author, Anupam B. Jena, MD, PhD, email jena@hcp.med.harvard.edu.
(doi:10.1001/jamainternmed.2024.8432)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: The results of this study suggest that mRNA COVID-19 vaccination may be a protective factor against post–COVID-19 condition in children following SARS-CoV-2 infection. These findings suggest benefits of COVID-19 vaccination beyond those associated with protection against acute COVID-19 and may encourage increased pediatric uptake.
Corresponding Author: To contact the corresponding author, Anna R. Yousaf, MD, email pgy6@cdc.gov.
(doi:10.1001/jamanetworkopen.2024.59672)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
About The Study: This cohort study found no increase in sudden cardiac arrest/sudden cardiac death in young competitive athletes in the U.S. during the COVID-19 pandemic, suggesting that reports asserting otherwise were overestimating the cardiovascular risk of COVID-19 infection, vaccination, and myocarditis. Many athlete cases shown in social media video montages occurred before the pandemic yet claimed COVID-19 infection or vaccination raised the risk of sudden cardiac arrest/sudden cardiac death.
Corresponding Author: To contact the corresponding author, Jonathan A. Drezner, MD, email jdrezner@uw.edu.
(doi:10.1001/jamanetworkopen.2024.61327)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
