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Self-Reported Student Mistreatment in US Medical Schools

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, FEBRUARY 24, 2020

Media advisory: To contact corresponding author Katherine A. Hill, B.A., B.S., email Bill Hathaway at william.hathaway@yale.edu. The full study and editor’s note are linked to this news release.

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Bottom Line: An analysis of annual surveys from graduating students at all U.S. allopathic medical schools suggests self-reported medical student mistreatment remains common and varies by sex, race/ethnicity and sexual orientation. This observational study included 27,504 unique student surveys, representing 72.1% of graduating medical school students in 2016 and 2017. The types of mistreatment students were questioned about included public humiliation, being threatened, physical harm and unwanted sexual advances, as well as discrimination based on gender, race/ethnicity and sexual orientation. Researchers report self-reported medical student mistreatment was common, with 35.4% reporting at least one type of mistreatment, the most common of which was public humiliation. A larger proportion of female students compared with male students reported at least one episode of mistreatment; Asian, underrepresented minority and multiracial students reported higher rates of mistreatment and discrimination based on race/ethnicity than white students; and a larger proportion of lesbian, gay or bisexual students reported an episode of mistreatment compared with heterosexual students. Limitations of the study include self-reported information and differences in how students may classify experiences. Authors acknowledge the results may underreport medical student mistreatment because some students who experienced mistreatment may have left medical school before graduation.

Authors: Katherine A. Hill, B.A., B.S., Yale School of Medicine, New Haven, Connecticut, and coauthors.

 

(doi:10.1001/jamainternmed.2020.0030)

Editor’s Note: The article includes conflict of interest and funding/support disclosures. Please see the articles for additional information, including other authors, author contributions and affiliations, conflicts of interest and financial disclosures, and funding and support.

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Marijuana Use Among Older Adults in US

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, FEBRUARY 24, 2020

Media advisory: To contact corresponding author Benjamin H. Han, M.D., M.P.H., email Ryan Dziuba at Ryan.Dziuba@nyulangone.org. The full study is linked to this news release.

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Bottom Line: Cannabis use apparently continues to increase among older adults in the U.S. based on findings reported in this research letter. Researchers analyzed national survey data from 2015-2018 for nearly 15,000 adults 65 and older to estimate how common past-year cannabis use was. Previous studies have indicated sharp increases from 2006-2016. Cannabis has been legalized in many states for medical and recreational use. Authors of the current study estimate the proportion of adults who reported past-year marijuana use increased from 2.4% to 4.2% from 2015 to 2018. There appeared to be significant increases in use during that time among women, people who were white or nonwhite racial/ethnic minorities, adults with a college education, people with higher incomes, those who are married, and adults who reported receiving mental health treatment or using alcohol, and people with diabetes. A limitation of the study is the possibility of limited recall by the respondents. There is a need to better understand both the benefits and risks of marijuana use among older adults.

Authors: Benjamin H. Han, M.D., M.P.H., and Joseph J. Palamar, Ph.D., M.P.H., of the New York University School of Medicine, New York.

 

(doi:10.1001/jamainternmed.2019.7517)

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USPSTF Statement on Screening for Cognitive Impairment in Older Adults

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, FEBRUARY 25, 2020

Media advisory: To contact the U.S. Preventive Services Task Force, email the Media Coordinator at Newsroom@USPSTF.net or call 202-572-2044. The full report and related articles are linked to this news release.

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Bottom Line: The U.S. Preventive Services Task Force (USPSTF) concludes that current evidence is insufficient to make a recommendation about screening for cognitive impairment in adults 65 or older. The USPSTF routinely makes recommendations about the effectiveness of preventive care services and this statement updates and reaffirms its 2014 statement that also concluded “the evidence was insufficient to assess the balance of benefits and harms of screening for cognitive impairment.” Dementia is a significant decline in one or more areas of cognition that interferes with a person’s independence in daily life and the condition affects an estimated 2.4 to 5.5 million people in the U.S.

 

(doi:10.1001/jama.2020.0435)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.

Note: More information about the U.S. Preventive Services Task Force, its process, and its recommendations can be found on the newsroom page of its website.

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How Decline in Memory, Gait Speed Are Associated With Dementia Risk

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, FEBRUARY 21, 2020

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. Every Wednesday and Friday, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: The risk of dementia in adults 60 and older who experience declines in both memory and gait speed was compared with adults who experience no decline or decline in either memory or gait speed only in this observational meta-analysis that included six studies with about 8,700 participants from the U.S. and Europe.

Authors: Qu Tian, Ph.D., M.S., of the National Institutes of Health in Baltimore, Maryland, is the corresponding author.

 

(10.1001/jamanetworkopen.2019.21636)

Editor’s Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflicts of interest and financial disclosures, and funding and support.

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https://jamanetwork.com/journals/jamaoncology/fullarticle/10.1001/jamaoncol.2019.6731?guestAccessKey=66aee2b5-455f-49de-9c29-daf806cc8bc3&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=022020

Alcohol-Induced Deaths in US

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, FEBRUARY 21, 2020

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. Every Wednesday and Friday, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: National vital statistics data from 2000 to 2016 were used to examine how rates of alcohol-induced deaths (defined as those deaths due to alcohol consumption that could be avoided if alcohol weren’t involved) have changed in the U.S. and to compare the results by demographic groups including sex, race/ethnicity, age, socioeconomic status  and geographic location. The study is accompanied by two commentaries.

Authors: Susan Spillane, Ph.D., of the National Cancer Institute in Rockville, Maryland, is the corresponding author.

 

(10.1001/jamanetworkopen.2019.21451)

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Glaucoma Care in Prison Inmates

JAMA Ophthalmology

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, FEBRUARY 20, 2020

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What The Study Did: Data from 82 prison inmates treated in a glaucoma clinic at an academic hospital were used in this observational study to report on how treatment and follow-up, including medication adherence, were are managed.

Authors: Levi N. Kanu, M.D., of the University of Illinois at Chicago, is the corresponding author.

  

(doi:10.1001/jamaophthalmol.2020.0001)

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‘Stranger Things’ Associated With Public Awareness of Rare Disorder

JAMA Otolaryngology-Head & Neck Surgery

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, FEBRUARY 20, 2020

Media advisory: To contact corresponding author Austin L. Johnson, B.S., email Melani Hamilton at melani.hamilton@okstate.edu. The full study is linked to this news release.

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Bottom Line: The actor who plays Dustin Henderson on the popular Netflix series “Stranger Things” was born with cleidocranial dysplasia (CCD), a rare disorder of which the most prominent features are missing or abnormal growth of the teeth and collarbones. The fictional character shares the condition with actor Gaten Matarazzo III and the show has featured scenes of Matarazzo’s Dustin educating others about it. The authors of this research letter used data from Google Trends and CCD-related foundations  to gauge public interest and awareness of the disorder after the release of each of the show’s three seasons. Researchers report that each season of the show was associated with an increase in weekly search interest for CCD above what would be expected. Data from most CCD-related foundations contacted weren’t quantifiable but web traffic to one site for a CCD-related information page reached 10,000 visits the week after the show’s third season premiered last summer. While study authors urge writers to exercise cautious when portraying characters with rare disorders, those portrayals might help to raise awareness of these conditions.

Authors: Austin L. Johnson, B.S., Oklahoma State University Center for Health Sciences, Tulsa, and coauthors

 

(doi:10.1001/jamaoto.2019.4791)

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Evaluating Risk of Cancer in Patients With Psoriasis, Psoriatic Arthritis

JAMA Dermatology

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, FEBRUARY 19, 2020

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What The Study Did: This observational study was a systematic review and meta-analysis that included 112 studies and examined the association between risk of cancer in patients with psoriasis or psoriatic arthritis, including the risk of specific cancers.

Authors: Sofie Vaengebjerg, M.D., of the University of Copenhagen in Denmark, is the corresponding author.

(doi:10.1001/jamadermatol.2020.0024)

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Estimating Effects of Indoor Tanning Regulations

JAMA Dermatology

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, FEBRUARY 19, 2020

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What The Study Did: This analysis estimated the health and economic consequences of indoor tanning regulations, such as banning indoor tanning devices or prohibiting their use by minors, in North America and Europe compared with current levels of use.

Authors: Louisa G. Gordon, Ph.D., of QIMR Berghofer Medical Research Institute in Brisbane, Australia, is the corresponding author.

(doi:10.1001/jamadermatol.2020.0001)

Editor’s Note: The article includes conflict of interest and funding/support disclosures. Please see the articles for additional information, including other authors, author contributions and affiliations, conflicts of interest and financial disclosures, and funding and support.

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Comparing Outcomes Between African American, White Women After Mammography-Detected Triple-Negative Breast Cancer

JAMA Surgery

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, FEBRUARY 19, 2020

Media advisory: The full study is linked to this news release.

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What The Study Did: Researchers compared treatment and survival rates between African American and white women following early detection with mammography of triple-negative breast cancer. African American women have a higher rate of death from breast cancer compared with white women, a disparity partly explained by a higher rate of this aggressive breast cancer.

Authors: Lisa A. Newman, M.D., M.P.H., of Weill Cornell Medicine in New York, is the corresponding author.

 

(doi:10.1001/jamasurg.2019.6032)

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Cannabis Use During Pregnancy

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, FEBRUARY 19, 2020

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. Every Wednesday and Friday, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: The large health care system Kaiser Permanente Northern California provides universal screening for prenatal cannabis use in women during pregnancy by self-report and urine toxicology testing. This observational study used data to examine the association of depression, anxiety, and trauma diagnoses and symptoms with cannabis use by women during pregnancy.

Authors: Kelly C. Young-Wolff, Ph.D., M.P.H., of Kaiser Permanente Northern California in Oakland, is the corresponding author.

 

(10.1001/jamanetworkopen.2019.21333)

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Investigating Medicaid Expansion’s Association With Insurance Status, Diagnosis, Treatment Among Patients With Cancer

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, FEBRUARY 19, 2020

Media advisory: The full study and commentary are linked to this news release.

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. Every Wednesday and Friday, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: More than 925,000 adults in the National Cancer Database with a new diagnosis of invasive breast, colon or lung cancer were included in this observational study that examined how Medicaid expansion under the Patient Protection and Affordable Care Act (ACA) was associated with insurance status, cancer stage at diagnosis and timely treatment.

Authors: Samuel U. Takvorian, M.D., M.S., of the University of Pennsylvania in Philadelphia, is the corresponding author.

 

(10.1001/jamanetworkopen.2019.21653)

Editor’s Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflicts of interest and financial disclosures, and funding and support.

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How Does Long-Term Quality of Life, Patient Satisfaction Compare For Appendicitis Treatments?

JAMA Surgery

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, FEBRUARY 19, 2020

Media advisory: To contact corresponding author  Paulina Salminen, M.D., Ph.D., email paulina.salminen@tyks.fi. The full study and commentary are linked to this news release.

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Bottom Line: Researchers compared long-term quality of life and patient satisfaction among those patients who were treated with antibiotics or who had their appendix removed for uncomplicated acute appendicitis. Evidence in recent years has indicated antibiotic treatment is a safe and efficient alternative to appendectomy. This study was a seven-year follow-up of a randomized clinical trial in Finland of patients with uncomplicated acute appendicitis who underwent appendectomy or who received antibiotics. The follow-up included 423 patients who completed questionnaires regarding quality of life and their level of satisfaction with the treatment received. Researchers found no difference between treatment groups in patient-rated quality of life or in satisfaction with the treatment if it was successful. Patients taking antibiotics who later had an appendectomy were less satisfied than patients with successful antibiotic or appendectomy treatments. Limitations of the study include use in the initial trial of an open surgical approach for appendectomy since laparoscopic appendectomy is the current standard associated with shorter hospital stays and less postoperative pain.

Authors: Paulina Salminen, M.D., Ph.D., of Turku University Hospital, Turku, Finland, and coauthors

 

(doi:10.1001/jamasurg.2019.6028)

Editor’s Note: The article includes conflict of interest and funding/support disclosures. Please see the articles for additional information, including other authors, author contributions and affiliations, conflicts of interest and financial disclosures, and funding and support.

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Charity Care Provided by Nonprofit Hospitals

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, FEBRUARY 17, 2020

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What The Study Did: Researchers looked at the net income of nonprofit hospitals in the U.S. and examined how their financial status was associated with the level of charity care they provided in 2017 for uninsured and insured patients.

Authors: Ge Bai, Ph.D., C.P.A., of the Johns Hopkins Carey Business School in Baltimore, is the corresponding author.

 

(doi:10.1001/jamainternmed.2019.7415)

Editor’s Note: The article includes conflict of interest and funding/support disclosures. Please see the articles for additional information, including other authors, author contributions and affiliations, conflicts of interest and financial disclosures, and funding and support.

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Examining How Often Care, ICU Admissions Were Consistent With Treatment-Limiting Orders Near End of Life

JAMA

EMBARGOED FOR RELEASE: 2 P.M. (ET), SUNDAY, FEBRUARY 16, 2020

Media advisory: The full study and editorial are linked to this news release. The study is being released to coincide with presentation at the Society of Critical Care Medicine’s 49th Critical Care Congress.

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What The Study Did: Patients with chronic life-limiting illnesses often have medical orders with treatment limitations in place regarding medical interventions and intensive care unit admissions near the end of their lives. This observational study included about 1,800 patients with such orders who were hospitalized within six months of their death to examine how often care was consistent with those orders.

Authors: Robert Y. Lee, M.D., M.S., of the University of Washington in Seattle, is the corresponding author.

 

(doi:10.1001/jama.2019.22523)

Editor’s Note: The article includes conflict of interest and funding/support disclosures. Please see the articles for additional information, including other authors, author contributions and affiliations, conflicts of interest and financial disclosures, and funding and support.

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Factors Associated With Health-Related Quality of Life in Patients With Facial Palsy

JAMA Otolaryngology-Head & Neck Surgery

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, FEBRUARY 13, 2020

Media advisory: The full study and commentary are linked to this news release.

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What The Study Did: Patients with facial palsy completed questionnaires to help identify socioeconomic, personality and mental health factors associated with their health-related quality of life, information that may be beneficial in interpreting treatment outcomes.

Authors: Tessa E. Bruins, B.Sc., of the University Medical Center Groningen, in Groningen, the Netherlands, is the corresponding author.

 

(doi:10.1001/jamaoto.2019.4559)

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Feasibility of Using Cells From Fat Tissue to Treat Scarred Vocal Cords

JAMA Otolaryngology-Head & Neck Surgery

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, FEBRUARY 13, 2020

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What The Study Did: This small trial examined the feasibility and effectiveness of injecting cells with regenerative properties that are from a patient’s fat tissue into scarred vocal cords of patients who had difficulty speaking.

Authors: Alexia Mattei, M.D., of La Conception University Hospital in Marseille, France, is the corresponding author.

 

(doi:10.1001/jamaoto.2019.4328)

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Clinical Trial Examines Subconcussive Head Impacts From Soccer

JAMA Ophthalmology

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, FEBRUARY 13, 2020

Media advisory: To contact corresponding author Keisuke Kawata, Ph.D., email Charles Conner-Rondot at crondot@indiana.edu. The full study and commentary are linked to this news release.

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Bottom Line: Subconcussive head impacts from sports are those that don’t cause symptoms of a concussion. This randomized clinical trial evaluated whether such subconcussive head impacts from soccer-ball headings impaired brain circuitry linking eye and cognitive functions in adult soccer players compared with a control group of players that only kicked the soccer ball. Neuro-ophthalmologic function was measured with a test of eye movement and brain functions such as attention, language and concentration. The study included 78 soccer players, of whom 40 players did 10 soccer-ball headings. Researchers report the kicking control group performed better on the test of neuro-ophthalmologic function at all points over 24 hours after the intervention than the heading group of players.  The findings suggest subconcussive head impacts may affect neuro-eye function, at least in the short term. Limitations of the study include an inability to determine the observed effects beyond 24 hours and it is unknown whether prior exposure to soccer-ball heading affected the players’ responses to 10 headings as part of the trial intervention.

Authors: Keisuke Kawata, Ph.D., Indiana University School of Public Health,­ Bloomington, and coauthors.

 

(doi:10.1001/jamaophthalmol.2019.6128)

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Evaluating Skin Cancer History by Sexual Orientation, Gender Identity

JAMA Dermatology

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, FEBRUARY 12, 2020

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Association Between Sexual Orientation and Lifetime Prevalence of Skin Cancer in the United States https://jamanetwork.com/journals/jamadermatology/fullarticle/10.1001/jamadermatol.2019.4196?guestAccessKey=b853325d-c507-49b8-8434-b967fae3000a&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=021220

 

Gender Identity and Lifetime Prevalence of Skin Cancer in the United States https://jamanetwork.com/journals/jamadermatology/fullarticle/10.1001/jamadermatol.2019.4197?guestAccessKey=62ee7daa-9c1f-4a56-a0b8-0caec9285cd4&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=021220

 

What The Studies Did: These two related studies and editorial examined the association of sexual orientation and gender identity with a history of self-reported skin cancer.

Authors: Arash Mostaghimi, M.D., M.P.A., M.P.H., of Brigham and Women’s Hospital and Harvard Medical School in Boston, is the corresponding author of both studies.

(doi:10.1001/jamadermatol.2019.4196 and 10.1001/jamadermatol.2019.4197)

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Analysis of Melanoma in US by Age Groups

JAMA Dermatology

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, NOVEMBER 13, 2019

Media advisory: The full study and podcast are linked to this news release.

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What The Study Did: This study used registry data to determine annual rates of melanoma in pediatric, adolescent, young adult and adult age groups, and the findings suggest an apparent decrease among adolescent and young adults between 2006 and 2015 but increases in older adults.

Authors: Jennifer M. Gardner M.D., of the Seattle Cancer Care Alliance, is the corresponding author.

 

(doi:10.1001/jamadermatol.2019.3353)

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Palliative vs Standard Care for Parkinson Disease

JAMA Neurology

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, FEBRUARY 10, 2020

Media advisory: The full study and editorial are linked to this news release.

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What The Study Did: This randomized clinical trial that included 210 patients with Parkinson disease and related disorders and 175 caregivers examined whether outpatient palliative care was associated with better patient or caregiver outcomes compared with standard care.

Authors: Benzi M. Kluger, M.D., of the University of Rochester Medical Center in Rochester, New York, is the corresponding author.

 

(doi:10.1001/jamaneurol.2019.4992)

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Heroin Use in US

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, FEBRUARY 11, 2020

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What The Study Did: Survey responses from a nationally representative group of 800,000 U.S. adults were used to examine changes in heroin use, heroin injection and heroin use disorder from 2002 to 2018.

Authors: Beth Han, M.D., Ph.D., M.P.H., of the Substance Abuse and Mental Health Services Administration in Rockville, Maryland, is the corresponding author.

 

(doi:10.1001/jama.2019.20844)

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‘Surprise’ Out-Of-Network Bills After In-Network Elective Surgery

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, FEBRUARY 11, 2020

Media advisory: To contact corresponding author Karan R. Chhabra, M.D., M.Sc., email Kara Gavin at kegavin@med.umich.edu. The full study and related articles are linked to this news release.

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Bottom Line: Claims data from a large health insurer were used to examine how often patients unexpectedly receive out-of-network bills after having in-network elective surgery.  These “surprise bills” typically occur when a patient receives care from a clinician, such as an anesthesiologist or surgical assistant, who doesn’t participate in that patient’s insurance network. This analysis included nearly 350,000 commercially insured patients who underwent elective surgery at in-network facilities with in-network primary surgeons between 2012 and 2017. The authors report that approximately 1 in 5 of these procedures resulted in an out-of-network bill, with an average potential balance of $2,011. Out-of-network bills were associated with anesthesiologists and surgical assistants in 37% of these surgeries. A limitation of the study is that claims data came from only one insurer.

Authors: Karan R. Chhabra, M.D., M.Sc., University of Michigan, Ann Arbor, and coauthors.

 

(doi:10.1001/jama.2019.21463)

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Are There Racial/Ethnic Disparities in Treatment for Acne?

JAMA Dermatology

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, FEBRUARY 5, 2020

Media advisory: The full study is linked to this news release.

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What The Study Did: Whether there are differences in treatment of acne by race/ethnicity, sex and type of insurance was the focus of this observational study that analyzed treatment and prescribing patterns for acne for nearly 30,000 patients.

Authors: Junko Takeshita, M.D., Ph.D., M.S.C.E., of the Perelman School of Medicine at the University of Pennsylvania in Philadelphia, is the corresponding author.

 

(doi:10.1001/jamadermatol.2019.4818)

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Association of Parent, Family Stressors With Screen Exposure Among Toddlers

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, FEBRUARY 5, 2020

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. Every Wednesday and Friday, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: This population-based study explored associations between parent and family stressors, such as parenting stress and lower household income, with child screen exposure and screen use paired with feeding in toddlers.

Authors: Katherine Tombeau Cost, Ph.D., of the Hospital for Sick Children in Toronto, is the corresponding author.

 

 

(10.1001/jamanetworkopen.2019.20557)

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Examining Patterns After Shift to Reference Pricing for Drugs

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, FEBRUARY 5, 2020

Media advisory: The full study and commentary are linked to this news release.

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. Every Wednesday and Friday, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: An economic evaluation of 3.3 million drug insurance claims looked at whether implementing reference pricing was associated with physicians and patients adjusting to using the least expensive alternative within a drug class.

Authors: James C. Robinson, Ph.D., University of California, Berkeley, School of Public Health, is the corresponding author.

 

(10.1001/jamanetworkopen.2019.20544)

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Health Insurance Concerns of Adults Approaching Retirement

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, FEBRUARY 7 2020

Media advisory: The full study and commentary are linked to this news release.

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. Every Wednesday and Friday, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: An online survey study was conducted to gauge the perspectives of adults who are nearing retirement (ages 50 to 64) about their confidence in affording heath insurance, keeping a job or delaying retirement to have employer-sponsored health insurance; their concerns about potential changes to to health insurance because of changes to federal policies; and the avoidance of medical care or medications because of cost.

Authors: Renuka Tipirneni, M.D., M.Sc., of the University of Michigan in Ann Arbor, is the corresponding author.

 

(10.1001/jamanetworkopen.2019.20647)

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Examining Consumption of Processed Meat, Unprocessed Red Meat, Poultry or Fish With Risk of CVD, Death

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, FEBRUARY 3, 2020

Media advisory: The full study is linked to this news release.

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What The Study Did: Data for nearly 30,000 adults from six study groups in the U.S. were used to investigate associations between eating processed meat, unprocessed red meat, poultry or fish and the risk of cardiovascular disease and death from any cause.

Authors: Victor W. Zhong, Ph.D., of Cornell University in Ithaca, New York, is the corresponding author.

 

(doi:10.1001/jamainternmed.2019.6969)

Editor’s Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.

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Homicide Among Pregnant, Postpartum Women in Louisiana

JAMA Pediatrics

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, FEBRUARY 3, 2020

Media advisory: The full study is linked to this news release.

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What The Study Did: Researchers examined how often homicide was the cause of death among women in Louisiana who were pregnant or up to one year postpartum compared with other causes.

Authors: Maeve E. Wallace, Ph.D., of the Tulane University School of Public Health and Tropical Medicine in New Orleans, is the corresponding author.

 

(doi:10.1001/jamapediatrics.2019.5853)

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Changes in the Cost Over Time of HIV Antiretroviral Therapy in US

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, FEBRUARY 3, 2020

Media advisory: The full study is linked to this news release.

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What The Study Did: Researchers calculated the average cost of recommended initial HIV antiretroviral therapy (ART) regimens in the U.S. from 2012 to 2018 and analyzed how this cost has changed over the years. High ART costs are one of the factors that can lead to poor HIV treatment and outcomes in the U.S.

Authors: Rochelle P. Walensky, M.D., M.P.H., of Massachusetts General Hospital in Boston, is the corresponding author.

 

(doi:10.1001/jamainternmed.2019.7108)

Editor’s Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.

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Are Neurological Disorders Associated With Increased Risk of Suicide?

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, FEBRUARY 4, 2020

Media advisory: The full study is linked to this news release.

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What The Study Did: Nearly 40 years of registry data for 7.3 million people living in Denmark were used to examine whether people diagnosed with neurological disorders, including  dementia, stroke, epilepsy, Parkinson disease and multiple sclerosis, die by suicide more often than others.

Authors: Annette Erlangsen, Ph.D., of the Danish Research Institute for Suicide Prevention in Copenhagen, Denmark, is the corresponding author.

 

(doi:10.1001/jama.2019.21834)

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Do State Regulations Affect Adult Use of E-Cigarettes?

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, JANUARY 31, 2020

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. Every Wednesday and Friday, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: National data from 895,000 adults were used to examine how state regulations regarding electronic cigarettes were associated with their use among U.S. adults.

Authors: Wei Bao, Ph.D., of the University of Iowa College of Public Health in Iowa City, is the corresponding author.

 

(10.1001/jamanetworkopen.2019.20255)

Editor’s Note: The article includes funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.

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Rates of New Colorectal Cancer Cases as People Turn 50, Historically Begin Screening

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, JANUARY 31, 2020

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. Every Wednesday and Friday, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: Cancer registries representing about 28% of the U.S. population were used to examine how new cases of colorectal cancer increased from age 49 to 50, the age when many people of average risk for the disease historically began screening, although screening age recommendations vary.

Authors: Jordan J. Karlitz, M.D., of the Southeast Louisiana Veterans Health Care System and Tulane University School of Medicine in New Orleans, is the corresponding author.

 

(10.1001/jamanetworkopen.2019.20407)

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Effect of State Law Allowing Pharmacists to Dispense Naloxone Without Rx

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, JANUARY 31, 2020

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. Every Wednesday and Friday, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: Naloxone is a medication used to reverse an opioid overdose, and this study looked at how an Ohio law that allowed pharmacists to dispense naloxone without a prescription was associated with dispensing rates.

Authors: Pamela C. Heaton, Ph.D., of the University of Cincinnati in Ohio, is the corresponding author.

 

(10.1001/jamanetworkopen.2019.20310)

Editor’s Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.

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Suicidal Thoughts Among US Army Soldiers Deployed to Afghanistan

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, JANUARY 29, 2020

Media advisory: To contact corresponding author Robert J. Ursano, M.D., email email Sarah Marshall at sarah.marshall@usuhs.edu. The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. Every Wednesday and Friday, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

Bottom Line: Among nearly 4,000 U.S. Army soldiers deployed in Afghanistan, 11.7% reported suicidal thoughts at some point in their lives, 3.0% within the past year and 1.9% within the past 30 days on questionnaires completed at the midpoint of their deployment in 2012. This observational study used the questionnaires to analyze how common suicidal ideation and mental health disorders were during combat deployment and to examine the associated risk factors. The study is unique in its assessment of soldiers’ self-reported suicidal ideation and mental health disorders at the midpoint of deployment, a period when risk for suicide attempts appears to peak. The authors report risk factors associated with recent suicidal thoughts during deployment included being white, past noncombat trauma and past major depressive disorder. Limitations of the study include self-reported data and findings that may not generalize to other soldiers or civilians. The authors suggest major depressive disorder and noncombat trauma are important factors for identifying risk of suicidal thoughts during combat deployments.

Authors: Robert J. Ursano, M.D., Uniformed Services University of the Health Sciences, Bethesda, Maryland, and coauthors

 

(doi:10.1001/jamanetworkopen.2019.19935)

Editor’s Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.

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Associations Between Work Environment and Rushed, Missed Care Tasks in Nursing Homes

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, JANUARY 29, 2020

Media advisory: The full study and commentary are linked to this news release.

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. Every Wednesday and Friday, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: Associations between work environment (including staffing, culture and leadership) and self-reported missed or rushed tasks by care aides in nursing homes in Canada were analyzed in this observational study.

Authors: Yuting Song, Ph.D., of the University of Alberta in Edmonton, Canada, is the corresponding author.

 

(10.1001/jamanetworkopen.2019.20092)

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Self-Reported Secondhand Exposure to e-Cigarette Aerosol Among US Youth

JAMA Pediatrics

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, JANUARY 27, 2020

Media Advisory: The full study is linked to this news release.

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What The Study Did: This research letter reports on self-reported secondhand aerosol from electronic cigarettes using survey data from U.S. middle and high school students.

Author: Hongying Dai, Ph.D., of the University of Nebraska Medical Center in Omaha, is the corresponding author.

 

(doi:10.1001/jamapediatrics.2019.5665)

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Diabetes Screening in Barbershops to Identify Undiagnosed Black Men

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, JANUARY 27, 2020

Media Advisory: The full study is linked to this news release.

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What The Study Did: This research letter reports on diabetes screening in barbershops to identify undiagnosed black men.

Authors: David C. Lee, M.D., of the NYU Grossman School of Medicine in New York, is the corresponding author.

(doi:10.1001/jamainternmed.2019.6867)

Editor’s Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.

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Study Examines Poverty, Suicide Associations Among US Youth

JAMA Pediatrics

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, JANUARY 27, 2020

Media advisory: The full study is linked to this news release.

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What The Study Did: Associations between county-level concentrations of poverty in the United States and suicide rates among children and adolescents (ages 5 to 19) were explored in this observational study.

Authors: Jennifer A. Hoffman, M.D., of the Ann & Robert H. Lurie Children’s Hospital of Chicago, is the corresponding author.

 

(doi:10.1001/jamapediatrics.2019.5678)

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Unmet Need for Physicians, Services Among US Adults

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, JANUARY 27, 2020

Media Advisory: To contact corresponding author Laura Hawks, M.D., email David Cecere at dcecere@challiance.org. The full study, commentary and podcast are linked to this news release.

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Bottom Line: Twenty years of survey data from the Centers for Disease Control and Prevention were used to examine the unmet need to see a physician and for services among insured and uninsured adults from 1998 to 2017, a time of change in the U.S. health care system that included passage of the Affordable Care Act (ACA). The proportion of adults who reported being unable to see a physician because of cost increased, with worsening access among insured adults whose numbers increased over time. The proportion of adults with chronic medical conditions unable to see a physician because of cost also increased for most conditions. A bigger share of adults received guideline-recommended cholesterol tests and flu shots but the proportion of women receiving mammograms decreased. A limitation of the study was the use of self-reported data.

Authors: Laura Hawks, M.D., Cambridge Health Alliance, Cambridge, Massachusetts, and coauthors.

 

(doi:10.1001/jamainternmed.2019.6538)

Editor’s Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.

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