What The Viewpoint Says: The amplified impact of COVID-19 on vulnerable populations has important implications for individuals at risk of or exploited in human trafficking.
Authors: Jonathan Todres, J.D., of the Georgia State University College of Law in Atlanta, is the corresponding author.
(doi:10.1001/jamapediatrics.2020.3595)
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What The Editorial Says: Authors of this editorial review the evidence for the management of patients with the acute respiratory distress syndrome (ARDS) that may apply to patients with severe COVID-19, what has been learned about treatment of these patients, and the gaps in knowledge that remain.
Authors: Carolyn S. Calfee, M.D., M.A.S., of the University of California, San Francisco, is the corresponding author.
(doi:10.1001/jamainternmed.2020.6047)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Changes over nearly two decades in the rate of hospitalizations and in-hospital deaths from alcohol use disorder in the U.S. were examined in this study.
Authors: Jasvinder A. Singh, M.B.B.S., M.P.H., of the University of Alabama at Birmingham, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.16580)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Researchers in this observational study investigated the association between the amount of sleep at night and cognitive decline among participants in two large studies on aging.
Authors: Wuxiang Xie, Ph.D., of Peking University First Hospital in Beijing, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.13573)
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What The Study Did: This randomized clinical trial compared the effectiveness of two smartphone apps that use different approaches to help smokers quit.
Authors: Jonathan B. Bricker, Ph.D., of the Fred Hutchinson Cancer Research Center in Seattle, is the corresponding author.
(doi:10.1001/jamainternmed.2020.4055)
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What The Study Did: Researchers in this observational study examined the association between wearing eyeglasses daily and susceptibility to COVID-19.
Authors: Yiping Wei, M.D., Ph.D., and Jianjun Xu, M.D., Ph.D., of the Second Affiliated Hospital of Nanchang University in Nanchang, China, are the corresponding authors.
(doi:10.1001/jamaophthalmol.2020.3906)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Researchers examined changes in the proportion of female corresponding authors in bioRxiv (biorxiv.org) and medRxiv (medrxiv.org), which are online archive and distribution services for unpublished preprint research in the life and health sciences, respectively, before and during the COVID-19 pandemic.
Authors: Mackenzie R. Wehner, M.D, MPhil., of the University of Texas MD Anderson Cancer Center in Houston, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.20335)
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What The Study Did: This laboratory study assessed the efficacy of the nasal antiseptic solution povidone-iodine against transmission of SARS-C0V-2.
Authors: Samantha Frank, M.D., of the University of Connecticut School of Medicine in Farmington, is the corresponding author.
(doi:10.1001/jamaoto.2020.3053)
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What The Study Did: Changes in lung cancer treatment during the COVID-19 pandemic were evaluated in this study.
Authors: Nathaniel Bouganim, M.D., of Cedars Cancer Center, McGill University Health Centre in Montreal, is the corresponding author.
(doi:10.1001/jamaoncol.2020.4408)
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What The Study Did: Researchers in this observational study investigated the association between the number of cups of coffee consumed per day and survival in patients with advanced or metastatic colorectal cancer.
Authors: Christopher Mackintosh, M.L.A., a medical student at the Mayo Clinic School of Medicine in Rochester, Minnesota, is the corresponding author.
(doi:10.1001/jamaoncol.2020.3938)
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What The Study Did: Researchers investigated differences in quality of life and other outcomes (including physical functioning, body image, sexual health, anxiety and depressive symptoms) by type of breast cancer surgery (such as mastectomy or breast conserving surgery) in women 40 and younger.
Authors: Shoshana M. Rosenberg, Sc.D., M.P.H., of the Dana-Farber Cancer Institute in Boston, is the corresponding author.
(doi:10.1001/jamasurg.2020.3325)
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What The Study Did: This observational study looked at whether adverse pregnancy outcomes such as preterm delivery, gestational diabetes and low birth weight are associated with an increased risk of atherosclerotic cardiovascular disease in postmenopausal women, independent of traditional risk factors.
Authors: Nisha I. Parikh, M.D., M.P.H., of the University of California, San Francisco, is the corresponding author.
(doi:10.1001/jamacardio.2020.4097)
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What The Study Did: This case-control study compares the rates of test results indicating SARS-CoV-2 infection among children and adults admitted to a single hospital in Milan, Italy, for noninfectious reasons and without COVID-19 symptoms.
Authors: Carlo Agostoni, M.D., of Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico in Milan, Italy, is the corresponding author.
(doi:10.1001/jamapediatrics.2020.3595)
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What The Article Says: This Viewpoint examines the evidence for vaccination of children against COVID-19.
Authors: Lainie Friedman Ross, M.D., Ph.D., of the University of Chicago, is the corresponding author.
(doi:10.1001/jamapediatrics.2020.3019)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Psychological symptoms, nonsuicidal self-injury and suicidal ideation, plans, and attempts among children and adolescents were investigated in this observational study before the COVID-19 outbreak started (early November 2019) and two weeks after school reopening (mid-May 2020) in an area of China with low risk of COVID-19.
Authors: Ying Sun, M.D., of Anhui Medical University in the Anhui province of China, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.21482)
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What The Study Did: This study investigated the use of cardiac magnetic resonance imaging in competitive college athletes who recovered from COVID-19 to detect myocardial inflammation that would identify high-risk athletes for return to competitive play.
Authors: Saurabh Rajpal, M.B.B.S., M.D., of Division of Ohio State University in Columbus, is the corresponding author.
(doi:10.1001/jamacardio.2020.4916)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Researchers compared changes from 2000 to 2017 in premature deaths in the U.S. due to drug poisonings, suicide and alcohol-induced causes by geographic areas and demographic characteristics.
Authors: Meredith S. Shiels, Ph.D., of the National Cancer Institute in Rockville, Maryland, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.16217)
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What The Article Says: This Viewpoint discusses the disproportionate burdens related to COVID-19 experienced by minority populations as well as strategies to limit disparities in health care, access and outcomes.
Authors: Regan W. Bergmark, M.D., of Harvard Medical School and Brigham and Women’s Hospital in Boston, is the corresponding author.
(doi:10.1001/jamaoto.2020.2874)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: This observational study investigated demographic and military service characteristics associated with suicide risk among U.S. veterans after the transition from active military service to civilian life.
Authors: Mark A. Reger, Ph.D., of the Veterans Affairs Puget Sound Health Care System in Seattle, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.16261)
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What The Study Did: The clinical profile and outcomes of 3,222 young adults (ages 18 to 34 years) who required hospitalization for COVID-19 in the U.S. are examined in this case series.
Authors: Scott D. Solomon, M.D., of Brigham and Women’s Hospital in Boston, is the corresponding author.
(doi:10.1001/jamainternmed.2020.5313)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Over the first 12 weeks of the COVID-19 pandemic, about 700 patients were admitted to Brigham and Women’s Hospital in Boston with COVID-19 and more than 8,000 patients without COVID-19. Researchers in this study reviewed all patients diagnosed with COVID-19 on hospital day three or later or within 14 days of hospital discharge to quantify the incidence of nosocomial transmission and to assess the effectiveness of the infection control program at the hospital.
Authors: Chanu Rhee, M.D., M.P.H., of Harvard Medical School and Harvard Pilgrim Health Care Institute in Boston, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.20498)
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EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, SEPTEMBER 9, 2020
Media advisory: The full study and related articles are linked to this news release. A live stream is planned for 12:30 P.M. Thursday, September 10, at this link: https://ja.ma/covidtrends
What The Study Did: National survey data were used to examine how blood pressure control changed overall among U.S. adults with high blood pressure between 1999-2000 and 2017-2018 and by age, race, insurance type and access to health care.
Authors: Paul Muntner, Ph.D., of the University of Alabama at Birmingham, is the corresponding author.
(doi:10.1001/jama.2020.14545)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: The risk of future dementia associated with overall alcohol consumption and alcohol-induced loss of consciousness in a population of current drinkers was examined in this observational study with more than 131,000 adults.
Authors: Mika Kivimaki, Ph.D., of University College London in London, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.16084)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Anonymous mobile phone location data were used to examine travel and home dwelling time patterns before and after enactment of stay-at-home orders in U.S. states to examine associations between changes in mobility and the COVID-19 curve.
Authors: Song Gao, Ph.D., and Jonathan A. Patz, M.D., of the University of Wisconsin in Madison, are the corresponding authors.
(doi:10.1001/jamanetworkopen.2020.20485)
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What The Study Did: This study combined the results of 21 studies to estimate the proportion of Black children, adolescents and adults with attention-deficit/hyperactivity disorder (ADHD) and identify the associated risk factors.
Authors: Jude Mary Cénat, Ph.D., of the University of Ottawa in Ottawa, Canada, is the corresponding author.
(doi:10.1001/jamapsychiatry.2020.2788)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Clinical features of COVID-19 are compared in this observational study with those of influenza A and B in U.S. children.
Authors: Xiaoyan Song, Ph.D, M.B.B.S., of the Children’s National Hospital in Washington, D.C., is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.20495)
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What The Study Did: This study examined the location of mass shootings (four or more people injured or killed by a firearm) last year relative to schools and other places frequented by children.
Authors: Michael L. Nance, M.D., of Children’s Hospital of Philadelphia, is the corresponding author.
(doi:10.1001/jamapediatrics.2020.3371)
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What The Article Says: A hospitalist charts his emotional journey in this narrative essay from when once brightly colored signs declared hospital workers as heroes to now when the signs have faded and the steady and intense work of helping patients with COVID-19 has seemingly become mundane.
Authors: Bernard E. Trappey, M.D., of the University of Minnesota in Minneapolis, is the author.
(doi:10.1001/jama.2020.17249)
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What The Study Did: Researchers investigated data collection and sharing practices of mobile apps played by preschool-age children and the associated sociodemographic characteristics of the children.
Authors: Jenny S. Radesky, M.D., of the University of Michigan Medical School in Ann Arbor, is the corresponding author.
(doi:10.1001/jamapediatrics.2020.3345)
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What The Study Did: Survey data were used to assess changes in the use of electronic cigarettes among U.S. adults from 2016 to 2018.
Authors: Michael J. Blaha, M.D., M.P.H., of the Johns Hopkins Ciccarone Center for the Prevention of Cardiovascular Disease in Baltimore, is the corresponding author.
(doi:10.1001/jamainternmed.2020.2817)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: This observational study examines whether patients’ most recent vitamin D levels and treatment for insufficient vitamin D levels are associated with test results for COVID-19.
Authors: David O. Meltzer M.D., Ph.D., of the University of Chicago, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.19722)
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What The Article Says: This Viewpoint discusses how the COVID-19 pandemic may reshape clinical practice and clinical research as new technologies are incorporated and old practices are revisited and revamped.
Authors: Lillian L. Siu, M.D., of the Princess Margaret Cancer Centre in Toronto, Canada, is the corresponding author.
(doi:10.1001/jamaoncol.2020.4240)
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What The Article Says: This essay highlights the lessons to be learned from the COVID-19 pandemic on the importance of recognizing communication difficulties among those with hearing impairment.
Authors: Maura K. Cosetti, M.D., of the New York Eye and Ear Infirmary of Mount Sinai in New York, is the author.
(doi:10.1001/jamaoto.2020.2532)
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What The Article Says: The timing of performing tracheostomies, which are aerosol-generating procedures that may cause increased risk of COVID-19 transmission to health care workers, is examined in this Viewpoint..
Authors: Michael J. Brenner, M.D., of the University of Michigan Medical School in Ann Arbor, is the corresponding author.
(doi:10.1001/jamaoto.2020.2630)
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EMBARGOED FOR RELEASE: 10 A.M. (ET), WEDNESDAY, SEPTEMBER 2, 2020
Media advisory: The full study and editorial are linked to this news release. This study is being published to coincide with the release of guidelines from the World Health Organization regarding use of corticosteroids for treatment of critically ill COVID-19 patients.
What The Study Did: The results of seven randomized clinical trials with 1,703 critically ill patients with COVID-19 were combined to estimate the association between administration of corticosteroids compared with usual care or placebo and the risk of death after 28 days.
Authors: Jonathan A.C. Sterne, M.A., M.Sc., Ph.D., of the University of Bristol in England, is the corresponding author.
(doi:10.1001/jama.2020.17023)
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EMBARGOED FOR RELEASE: 10 A.M. (ET), WEDNESDAY, SEPTEMBER 2, 2020
Media advisory: The full study and editorial are linked to this news release. A visual abstract is below. This study is being published to coincide with the release of guidelines from the World Health Organization regarding use of corticosteroids for treatment of critically ill COVID-19 patients.
What The Study Did: This randomized clinical trial of patients with severe COVID-19 was stopped early after results from another trial were released but this study investigated whether intravenous hydrocortisone (administered either as a seven-day fixed-dose course or restricted to when shock is clinically evident) improved 21-day organ support–free days.
Authors: Derek C. Angus, M.D., M.P.H., of the University of Pittsburgh, is the corresponding author.
Visual Abstract
(doi:10.1001/jama.2020.17022)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: This is a survey study that examines how common depression symptoms are among U.S. adults during the COVID-19 pandemic compared with before the pandemic.
Authors: Sandro Galea, M.D., Dr.P.H., of the Boston University School of Public Health in Boston, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.19686)
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What The Study Did: This observational study examined the potential for airborne spread of COVID-19 through investigation of an outbreak among bus riders in Eastern China.
Authors: Feng Ling, M.D., of the Zhejiang Provincial Center for Disease Control and Prevention in Hangzhou, China, and Guozhang Xu, M.D. of the Ningbo Municipal Center for Disease Control and Prevention in Ningbo, China, are the corresponding authors.
(doi:10.1001/jamainternmed.2020.5225)
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What The Viewpoint Says: The different ways treatment and research on psychiatric disorders have shifted because of COVID-19 are assessed in this Viewpoint, which suggests what changes should remain after the pandemic.
Authors: Carlos Blanco, M.D., Ph.D., of the National Institute on Drug Abuse in Bethesda, Maryland, is the corresponding author.
(doi:10.1001/jamapsychiatry.2020.3177)
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EMBARGOED FOR RELEASE: 10 A.M. (ET), WEDNESDAY, SEPTEMBER 2, 2020
Media advisory: The full study and editorial are linked to this news release. A visual abstract is below. This study is being published to coincide with the release of guidelines from the World Health Organization regarding use of corticosteroids for treatment of critically ill COVID-19 patients.
What The Study Did: This randomized clinical trial in Brazil of 299 patients with COVID-19 and moderate or severe acute respiratory distress syndrome (ARDS) examined if intravenous dexamethasone plus standard care compared with standard care alone would increase the number of days patients were alive and free from mechanical ventilation.
Authors: Luciano C. P. Azevedo, M.D., Ph.D., of Hospital Sirio-Libanes in São Paulo, Brazil, is the corresponding author.
Visual Abstract
(doi:10.1001/jama.2020.17021)
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EMBARGOED FOR RELEASE: 10 A.M. (ET), WEDNESDAY, SEPTEMBER 2, 2020
Media advisory: The full study and editorial are linked to this news release. A visual abstract is below. This study is being published to coincide with the release of guidelines from the World Health Organization regarding use of corticosteroids for treatment of critically ill COVID-19 patients.
What The Study Did: The purpose of this randomized clinical trial in France was to evaluate the effect of low-dose hydrocortisone for the treatment of ICU patients with COVID-19-related acute respiratory failure but the trial was stopped early.
Authors: Pierre-François Dequin, M.D., Ph.D., of Médecine Intensive-Réanimation in Tours, France, is the corresponding author.
Visual Abstract
(doi:10.1001/jama.2020.16761)
Editor’s Note: The article includes conflicts of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, AUGUST 31, 2020
Media advisory: The full study and editor’s note are linked to this news release. This paper will be presented at the European Society of Cardiology Congress 2020: The Digital Experience on August 31 in an online presentation.
What The Study Did: The use of a smartwatch versus the standard measure of electrocardiographic recordings in patients with acute coronary syndromes is evaluated in this case series.
Authors: Ciro Indolfi, M.D., of Magna Graecia University in Catanzaro, Italy, is the corresponding author.
(doi:10.1001/jamacardio.2020.3538)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About The JAMA Pediatrics Patient Page: How parents can help young children and children with special needs work through changes and disruptions during the COVID-19 pandemic is discussed in this Patient Page, which is a public service of JAMA Pediatrics.
Authors: Michele Kong, M.D., of the University of Alabama at Birmingham, and Lindsay A.Thompson, M.D., M.S., of the University of Florida in Gainesville, are the authors.
(doi:10.1001/jamapediatrics.2020.2478)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
What The Study Did: This case series of 91 children with COVID-19 in South Korea examined how long SARS-CoV-2 RNA is detected in children and whether children with COVID-19 can be identified by symptoms.
Authors: Jong-Hyun Kim, M.D., Ph.D., of the Catholic University of Korea, and Eun Hwa Choi, M.D., Ph.D., of the Seoul National University College of Medicine, are the corresponding authors.
(doi:10.1001/jamapediatrics.2020.3988)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
What The Study Did: Researchers investigated differences by gender in the distribution of endowed chairs at top medical schools in the U.S. and examined if gender was associated with holding an endowed chair.
Authors: Reshma Jagsi, M.D., D.Phil., of the University of Michigan in Ann Arbor, is the corresponding author.
(doi:10.1001/jamainternmed.2020.2677)
Editor’s Note: The article includes conflict of interest disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: This randomized clinical trial determined whether a coached, digital cognitive behavior therapy self-help program improved outcomes for college women with eating disorders compared with referral to usual care.
Authors: Denise E. Wilfley, Ph.D., of the Washington University School of Medicine in St. Louis, is the corresponding author.
Visual Abstract
(doi:10.1001/jamanetworkopen.2020.15633)
Editor’s Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.