Examining Association of Race With Death Among Patients Hospitalized With COVID-19

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, AUGUST 18, 2020

Media advisory: The full study and commentary are linked to this news release.

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: Researchers looked at the association between race and death among patients hospitalized with COVID-19 at 92 hospitals in 12 states.

Authors: Baligh R. Yehia, M.D., M.P.P., of Ascension Health in St. Louis, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2020.18039)

Editor’s Note: The article includes conflict of interest disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Parents’ Plans Regarding School Attendance for Kids

JAMA Pediatrics

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, AUGUST 14, 2020

Media advisory: The full study is linked to this news release.

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What The Study Did: This survey study describes the association of planned in-person school attendance during the COVID-19 pandemic with various factors, including family socioeconomic characteristics and parent attitudes and beliefs about school attendance for their children.

Authors: Emily Kroshus, Sc.D., M.P.H., of the Seattle Children’s Research Institute, is the corresponding author.

 

(doi:10.1001/jamapediatrics.2020.3864)

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Patterns in Daily Reported Infections, Deaths for COVID-19

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, AUGUST 17, 2020

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: Patterns in daily reported infections and deaths for COVID-19 are investigated in this study.

Authors: Sheraz Khan, Ph.D., of Massachusetts General Hospital and Harvard Medical School in Boston, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2020.17521)

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Assessment of COVID-19 Hospitalizations by Race/Ethnicity in 12 States

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, AUGUST 17, 2020

Media advisory: The full study is linked to this news release.

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What The Study Did: Data from a COVID-19 tracking project were used to assess how common COVID-19 infection was by race/ethnicity in 12 states in this observational study.

Authors: Pinar Karaca-Mandic, Ph.D., of theUniversity of Minnesota in Minneapolis, is the corresponding author.

 

(doi:10.1001/jamainternmed.2020.3857)

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Policy Implications of Orphan Drug Designation for Remdesivir to Treat COVID-19

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, AUGUST 17, 2020

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What The Study Did: This Viewpoint highlights loopholes in U.S. orphan drug policy as exemplified by the use of remdesivir to treat COVID-19.

Authors: Kao-Ping Chua, M.D., Ph.D., of the University of Michigan in Ann Arbor, is the corresponding author.

 

(doi:10.1001/jamainternmed.2020.2759)

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Is Exposure to BPA Associated With Long-Term Risk of Death?

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, AUGUST 17, 2020

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: Whether exposure to bisphenol A (BPA), a chemical found in many consumer products, is associated with the long-term risk of death from cardiovascular disease, cancer or any cause among U.S. adults was examined in this observational study.

Authors: Wei Bao, M.D., Ph.D., of the University of Iowa in Iowa City, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2020.11620)

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Prescription Opioid Use, Misuse Among Cancer Survivors

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, AUGUST 17, 2020

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: This survey study looked at the frequency of prescription opioid use and misuse among adult cancer survivors compared with individuals without cancer.

Authors: Henry S. Park, M.D., M.P.H., of the Yale University School of Medicine in New Haven, Connecticut, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2020.13605)

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Comparing ICD-10 Codes With Electronic Medical Records Among Patients With COVID-19 Symptoms

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, AUGUST 14, 2020

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: The goal of this study was to compare International Statistical Classification of Diseases and Related Health Problems, Tenth Revision (ICD-10) codes with manual electronic medical records review in capturing symptoms of fever, cough and shortness of breath (dyspnea) among patients being tested for SARS-CoV-2 infection.

Authors: Rashmee U. Shah, M.D., M.S., of the University of Utah School of Medicine in Salt Lake City, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2020.17703)

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Interest in Quitting Vaping Among Adolescents

JAMA Pediatrics

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, AUGUST 17, 2020

Media advisory: The full study is linked to this news release.

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What The Study Did: Adolescents using electronic cigarettes were asked if they had seriously thought about or tried to quit vaping.

Authors: Tracy T. Smith, Ph.D., of the Medical University of South Carolina in Charleston, is the corresponding author.

 

(doi:10.1001/jamapediatrics.2020.2348)

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Comparing Excess Deaths in New York During COVID-19 With 1918 Influenza Pandemic

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, AUGUST 13, 2020

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: Excess deaths in New York during the peak of the 1918 influenza pandemic were compared with those during the initial period of the COVID-19 outbreak in this study.

Authors: Jeremy S. Faust, M.D., M.S., of Brigham and Women’s Hospital and Harvard Medical School in Boston, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2020.17527)

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COVID-19 Outcomes in French Nursing Homes With Staff Confinement

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, AUGUST 13, 2020

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: COVID-19–related outcomes in French nursing homes that implemented voluntary staff confinement with residents are investigated in this study.

Authors: Joel Belmin, M.D., Ph.D., of the Hopital Charles Foix in  Ivry-sur-Seine, France, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2020.17533)

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Outcomes Associated With Kinin B2 Receptor Antagonist for Treatment of COVID-19

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, AUGUST 13, 2020

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: The association between receipt of the bradykinin 2 (B2) receptor antagonist icatibant and improved oxygenation in patients with COVID-19 is investigated in this study.

Authors: Frank L. van de Veerdonk, M.D., Ph.D., of the Radboud University Medical Center in Nijmegen, the Netherlands, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2020.17708)

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Evidence of Direct Viral Damage to Olfactory Complex in Patients Testing Positive for SARS-CoV-2

JAMA Otolaryngology–Head & Neck Surgery

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, AUGUST 13, 2020

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What The Article Says: Researchers report the clinicopathologic and autopsy findings observed in the olfactory system of two patients with SARS-CoV-2-positive nasal swabs.

Authors: Patrizia Morbini M.D., Ph.D., of the University of Pavia in Pavia, Italy, is the corresponding author.

(doi:10.1001/jamaoto.2020.2366)

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USPSTF Recommendation on Behavioral Counseling to Prevent Sexually Transmitted Infections

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, AUGUST 18, 2020

Media advisory: To contact the U.S. Preventive Services Task Force, email the Media Coordinator at Newsroom@USPSTF.net or call 202-572-2044. The full report and related articles are linked to this news release.

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Bottom Line: The U.S. Preventive Services Task Force (USPSTF) recommends behavioral counseling to prevent sexually transmitted infections (STIs) for all sexually active adolescents and for adults at increased risk. Sexually transmitted infections are on the rise across the United States, with approximately 20 million new cases each year. If untreated, STIs can lead to serious health complications including infertility, AIDS and cancer. The USPSTF routinely makes recommendations about the effectiveness of preventive care services and this statement is consistent with its 2014 recommendation but differs by offering a broader range of effective counseling approaches.

(doi:10.1001/jama.2020.13095)

 

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.

Note: More information about the U.S. Preventive Services Task Force, its process, and its recommendations can be found on the newsroom page of its website.

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Radiotherapy, Androgen Deprivation Timing and Implications for Prostate Cancer Treatment During COVID-19

JAMA Oncology

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, AUGUST 13, 2020

Media advisory: The full study is linked to this news release.

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What The Study Did: National Cancer Database data from 2004 to 2014 were used to examine the association between overall survival and timing of radiotherapy relative to androgen deprivation therapy in patients with prostate cancer.

Authors: Vinayak Muralidhar, M.D., M.Sc., of the Dana-Farber Cancer Institute/Brigham and Women’s Hospital and Harvard Medical School in Boston is the corresponding author.

 

(doi:10.1001/jamaoncol.2020.3545)

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Disparities in Cancer Outcomes Due to COVID-19

JAMA Oncology

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, AUGUST 13, 2020

Media advisory: The full article is linked to this news release.

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What The Viewpoint Says: This Viewpoint calls for greater attention to racial and socioeconomic health disparities affecting patients with cancer in the setting of COVID-19.

Authors: Onyinye D. Balogun, M.D., of Weill Cornell Medicine in New York, is the corresponding author.

 

(doi:10.1001/jamaoncol.2020.3327)

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Examining Long-Term Mental Health After 2011 Japan Earthquake, Tsunami

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, AUGUST 14, 2020

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: Researchers looked at whether symptoms of posttraumatic stress and depression persisted among older adults five years after the 2011 Great East Japan earthquake and tsunami.

Authors: Shiho Kino, Ph.D., of the Harvard T.H. Chan School of Public Health in Boston, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2020.13437)

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Having COVID-19

JAMA Cardiology

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, AUGUST 12, 2020

Media advisory: The full study is linked to this news release.

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What The Article Says: This essay describes the author’s experience of having COVID-19.

Authors: Janet M. Shapiro, M.D., of the Icahn School of Medicine at Mount Sinai in New York, is the author.

 

(doi:10.1001/jamacardio.2020.3247)

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Diabetes, Weight Change and Pancreatic Cancer Risk

JAMA Oncology

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, AUGUST 13, 2020

Media advisory: The full study is linked to this news release.

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What The Study Did: Researchers investigated an association between the duration of diabetes and recent weight loss with subsequent risk of pancreatic cancer in this observational study.

Authors: Chen Yuan, Sc.D., of the Dana-Farber Cancer Institute and Harvard Medical School in Boston, is the corresponding author.

 

(doi:10.1001/jamaoncol.2020.2948)

Editor’s Note: The article includes conflicts of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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SARS-CoV-2 Infection Among Health Care Workers in Hospital

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, AUGUST 11, 2020

Media advisory: The full study is linked to this news release.

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What The Study Did: This study sought to establish the rate of COVID-19 among health care workers through widespread screening for SARS-CoV-2 exposure in a large community hospital.

Authors: Allen Jeremias, M.D., M.Sc., of  St Francis Hospital in Roslyn, New York, is the corresponding author.

 

(doi:10.1001/jamainternmed.2020.4214)

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Filtration Efficiency of Hospital Face Mask Alternatives During COVID-19 Pandemic

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, AUGUST 11, 2020

Media advisory: The full study and commentary are linked to this news release.

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What The Study Did: Researchers performed a series of FFE (fitted filtration efficiency) evaluations for a wide range of 29 respirators and face masks used by health care facilities, including expired N95 respirators, N95 respirators that have undergone sterilization, imported respirators approved by the U.S. Centers for Disease Control and Prevention, respirators not listed as approved, and surgical or procedure masks with ties and ear loops in this quality-improvement study.

Authors: Emily E. Sickbert-Bennett, Ph.D., M.S., of  UNC Health Care in Chapel Hill, North Carolina, is the corresponding author.

 

(doi:10.1001/jamainternmed.2020.4221)

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Assessment of Lupus Anticoagulant Positivity in Patients With COVID-19

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, AUGUST 12, 2020

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: How common lupus anticoagulant (LA) positivity is in patients with COVID-19 was assessed in this observational study, which also examined the association of LA positivity with patient outcomes.

Authors: Morayma Reyes Gil, M.D., Ph.D., of Montefiore Medical Center in New York, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2020.17539)

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K-12 Virtual Schooling, COVID-19 and Student Success

JAMA Pediatrics

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, AUGUST 11, 2020

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What The Viewpoint Says: This Viewpoint advises parents on how to assess virtual schooling options for their children for the fall semester during the COVID-19 pandemic.

Authors: Lindsay A. Thompson, M.D., M.S., of the University of Florida in Gainesville, is the corresponding author.

 

(doi:10.1001/jamapediatrics.2020.3800)

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Operational Considerations on Academy Guidance for K-12 School Reentry

JAMA Pediatrics

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, AUGUST 11, 2020

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What The Viewpoint Says: Guidelines from the American Academy of Pediatrics on K-12 school reentry are discussed in this Viewpoint.

Authors: C. Jason Wang, M.D., Ph.D., of the Stanford University School of Medicine in Stanford, California, is the corresponding author.

 

(doi:10.1001/jamapediatrics.2020.3871)

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ECMO for Patients With COVID-19, Severe Respiratory Failure

JAMA Surgery

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, AUGUST 11, 2020

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What The Study Did: We present our experience in using single-access, dual-stage venovenous ECMO (extracorporeal membrane oxygenation), with an emphasis on early extubation of patients while they received ECMO support.

Authors: Antone J. Tatooles, M.D., of Advocate Christ Medical Center in Oak Lawn, Illinois, is the corresponding author.

 

(doi:10.1001/jamasurg.2020.3950)

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Comparing Yoga, Other Treatments for Anxiety

JAMA Psychiatry

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, AUGUST 12, 2020

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What The Study Did: Researchers in this randomized clinical trial assessed whether Kundalini yoga and cognitive behavioral therapy (CBT) for generalized anxiety disorder are each more effective than stress education and whether yoga is noninferior to CBT for the treatment of the disorder.

Authors: Naomi M. Simon, M.D., M.Sc., of the New York University Grossman School of Medicine in New York, is the corresponding author.

 

(doi:10.1001/jamapsychiatry.2020.2496)

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Clarifying Consequences of COVID-19 in Pregnant Women, Newborns, Children

JAMA Pediatrics

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, AUGUST 10, 2020

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What The Study Did: This Viewpoint describes the need to understand the outcomes of the COVID-19 pandemic on pregnant women, newborns and children.

Authors: Melissa Wake, M.D., of the Royal Children’s Hospital in Parkville, Victoria, Australia, is the corresponding author.

 

(doi:10.1001/jamapediatrics.2020.2395)

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Survival on Heart Transplant Waiting List

JAMA Cardiology

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, AUGUST 12, 2020

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What The Study Did: Survival of patients on the heart transplant waiting list was examined in this observational study.

Authors: Elizabeth L. Godfrey, B.S., of the Baylor College of Medicine in Houston, is the corresponding author.

 

(doi:10.1001/jamacardio.2020.2795)

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Assessing Training in Health Disparities

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, AUGUST 10, 2020

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: This survey study described and compared the curriculum on health disparities from the perspective of program directors and perceptions of training among internal medicine residents.

Authors: Denise M. Dupras, M.D., Ph.D., of the Mayo Clinic College of Medicine and Science in Rochester, Minnesota, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2020.12757)

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Changes in Use of High-Dose Biotin Supplements Among US Adults

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, AUGUST 11, 2020

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What The Study Did: Nationally representative survey data were used to examine changes over nearly two decades in daily use of high-dose biotin supplements, which are marketed as stimulating growth of hair and nails.

Authors: Danni Li, Ph.D., of the University of Minnesota in Minneapolis, is the corresponding author.

 

(doi:10.1001/jama.2020.8144)

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Emergency Visits for Thunderstorm-Related Respiratory Illnesses

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, AUGUST 10, 2020

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What The Study Did: Researchers used atmospheric and lightning data for all counties in the continental United States from 1999 through 2012 to see if increases in emergency department visits for respiratory illnesses among older adults happen in the days surrounding thunderstorms because vulnerable groups and those with common chronic respiratory diseases may be susceptible to the atmospheric changes caused by these storms.

Authors: Anupam B. Jena, M.D., Ph.D., of Harvard Medical School in Boston, is the corresponding author.

 

(doi:10.1001/jamainternmed.2020.1672)

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Heart Attack Case Rates, Treatment Approaches, Outcomes During COVID-19 Pandemic

JAMA Cardiology

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, AUGUST 7, 2020

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What The Study Did: The increases and decreases in patient volume and associated changes in treatment experienced by individuals presenting with acute heart attack (myocardial infarction) before and immediately after the onset of the COVID-19 pandemic are examined in this observational study.

Authors: Ty J. Gluckman, M.D., of Providence St Joseph Health in Portland, Oregon, is the corresponding author.

 

(doi:10.1001/jamacardio.2020.3629)

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Does Physician Burnout, Depression, Career Satisfaction Differ by Race/Ethnicity?

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, AUGUST 7, 2020

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: This survey study of U.S. physicians examined whether there were differences by race/ethnicity in burnout, symptoms of depression, career satisfaction and work-life balance.

Authors: Magali Fassiotto, Ph.D., of the Stanford University School of Medicine in Stanford, California, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2020.12762)

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Molecular Viral Shedding Among Asymptomatic, Symptomatic Patients With SARS-CoV-2 Infection

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, AUGUST 6, 2020

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What The Study Did: SARS-CoV-2 molecular viral shedding in asymptomatic and symptomatic patients who were isolated in a community treatment center in South Korea is quantitatively described in this observational study.

Authors: Eunjung Lee, M.D., of the Soonchunhyang University Seoul Hospital in Seoul, South Korea, is the corresponding author.

 

(doi:10.1001/jamainternmed.2020.3862)

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Prioritizing Cancer Care During Pandemic

JAMA Oncology

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, AUGUST 6, 2020

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What The Article Says: The COVID-19 pandemic has forced oncology clinicians and administrators in the United States to set priorities for cancer care because of resource constraints. As oncology practices adapt to a contracted health care system, expertise gained from partnerships in low-resource settings can be used for guidance. This article provides a primer on priority setting in oncology and ethical guidance based on lessons learned from experience with cancer care priority setting in low-resource settings.

Authors: Rebecca J. DeBoer, M.D., M.A., of the University of California, San Francisco, is the corresponding author.

 

(doi:10.1001/jamaoncol.2020.2976)

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Perspectives on Oncology-Specific Language During COVID-19 Pandemic

JAMA Oncology

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, AUGUST 6, 2020

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What The Study Did: A practical communication guide designed for oncologists to assuage the fear, anger and anxiety among patients with cancer during the COVID-19 pandemic is proposed in this qualitative study.

Authors: Reshma Jagsi, M.D., D.Phil., of the University of Michigan in Ann Arbor, is the corresponding author.

 

(doi:10.1001/jamaoncol.2020.2980)

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Rethinking Clinical Trials Reform During COVID-19 Pandemic

JAMA Oncology

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, AUGUST 6, 2020

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What The Viewpoint Says: The COVID-19 pandemic is changing the way patients receive access to health care and how these changes can be implemented in clinical trials is discussed in this article.

Authors: Chadi Nabhan, M.D., M.B.A., Caris Life Sciences, Precision Oncology Alliance in Irving, Texas, is the corresponding author.

 

(doi:10.1001/jamaoncol.2020.3142)

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Practice Patterns, Responsiveness to Common Ocular Complaints Among Ophthalmology Centers During COVID-19

JAMA Ophthalmology

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, AUGUST 5, 2020

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What The Study Says: Practice patterns for common ocular complaints during the initial stage of the COVID-19 pandemic are reported in this observational study among comprehensive U.S. ophthalmology practices.

Authors: Ajay E. Kuriyan, M.D., of Mid Atlantic Retina, Wills Eye Hospital, Thomas Jefferson University in Philadelphia, is the corresponding author.

 

(doi:10.1001/jamaophthalmol.2020.3237)

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Racial Disparities in High-Cost Cancer Treatment for Children

JAMA Oncology

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, AUGUST 6, 2020

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What The Study Did: This observational study looked at whether race and socioeconomic factors were associated with children enrolled in national clinical trials receiving high-cost proton radiotherapy for treatment of cancer.

Authors: Daphne A. Haas-Kogan, M.D., of the Dana-Farber Cancer Institute in Boston, is the corresponding author.

 

(doi:10.1001/jamaoncol.2020.2259)

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Consequences of COVID-19 Pandemic on Manuscript Submissions by Women

JAMA Surgery

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, AUGUST 4, 2020

Media advisory: The full study is linked to this news release.

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What The Article Says: JAMA Surgery Editor Melina Kibbe, M.D., writes in this editorial: “The implications of these data demonstrating that fewer women are submitting manuscripts to JAMA Surgery during the pandemic are potentially far reaching. First and foremost, the adverse effect of the pandemic on the academic career progression of women may be significant. As publications are the currency of academia and one of the main metrics assessed for promotion and tenure, women may face future challenges in this arena. The reduction of manuscript submissions by women likely represents only one aspect of the spectrum of problems women are facing in academic medicine.”

Authors: Melina Kibbe, M.D., of the University of North Carolina at Chapel Hill, is the author.

 

(doi:10.1001/jamasurg.2020.3917)

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Skin Findings Described in Patients With Severe COVID-19

JAMA Dermatology

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, AUGUST 5, 2020

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What The Study Did: In this case series with four patients, the skin findings of livedo racemosa (skin discoloration) and retiform purpura are described in patients with severe COVID-19.

Authors: Joanna Harp, M.D., of NewYork-Presbyterian/Weill Cornell Medical College in New York, is the corresponding author.

 

(doi:10.1001/jamadermatol.2020.2800)

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Characteristics, Treatment of Radiation-Induced Hair Loss in Cancer Patients

JAMA Dermatology

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, AUGUST 5, 2020

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What The Study Did: Characteristics and response to treatment of persistent radiation-induced hair loss in patients with primary central nervous system tumors or head and neck cancer were examined in this observational study.

Authors: Mario E. Lacouture, M.D., of Memorial Sloan Kettering Cancer Center in New York, is the corresponding author.

 

(doi:10.1001/jamadermatol.2020.2127)

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Number of US Patients With Newly Identified Cancers Before, During COVID-19 Pandemic

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, AUGUST 4, 2020

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: Changes in the number of patients with newly identified cancer before and during the COVID-19 pandemic in the United States are examined in this observational study.

Authors: Harvey W. Kaufman, M.D., of Quest Diagnostics in Secaucus, New Jersey, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2020.17267)

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Health Care Worker Burnout During COVID-19 Pandemic

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, AUGUST 4, 2020

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: How common burnout was among frontline health care workers during the COVID-19 pandemic in Japan was evaluated in this observational study, which also examined the factors associated with it.

Authors: Takahiro Matsuo, M.D., of St Luke’s International Hospital in Tokyo, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2020.17271)

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Home Health Care Worker Experiences in New York During COVID-19 Pandemic

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, AUGUST 4, 2020

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What The Study Did: Experiences of home health care workers caring for older adults and for patients with chronic illnesses in New York during the COVID-19 pandemic are described in this analysis.

Authors: Madeline R. Sterling, M.D., M.P.H., M.S., of Weill Cornell Medicine in New York, is the corresponding author.

 

(doi:10.1001/jamainternmed.2020.3930)

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Recommendations to Improve Consensus of Determining Brain Death, Death by Neurologic Criteria

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, AUGUST 3, 2020

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What The Study Did: International professional societies developed recommendations for minimum clinical standards to determine brain death/death by neurologic criteria in adults and children to improve the consistency of these criteria within and among countries.

Authors: Gene Sung, M.D., M.P.H., of the University of Southern California in Los Angeles, is the corresponding author.

 

(doi:10.1001/jama.2020.11586)

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Detection of COVID-19 Viral Material on Environmental Surfaces of an Ophthalmology Exam Room

JAMA Ophthalmology

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, AUGUST 3, 2020

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What The Study Says: This study investigates the presence of SARS-CoV-2 on the environmental surfaces of an ophthalmology examination room after visits by patients who were asymptomatic and passed COVID-19 triage.

Authors: Hasan Aytoğan, M.D., of the İzmir Tepecik Training and Research Hospital in İzmir, Turkey, is the corresponding author.

 

(doi:10.1001/jamaophthalmol.2020.3154)

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ED Visits, Hospital Admissions in Health Care Systems in Early Months of COVID-19 Pandemic

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, AUGUST 3, 2020

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What The Study Did: Changes in emergency department visits and hospitalizations as the COVID-19 pandemic intensified in the U.S. are examined in this observational study that included 24 emergency departments in five health care systems in Colorado, Connecticut, Massachusetts, New York and North Carolina.

Authors: Edward R. Melnick, M.D., M.H.S., of the Yale University School of Medicine in New Haven, Connecticut, is the corresponding author.

 

(doi:10.1001/jamainternmed.2020.3288)

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Assessing Telemedicine Unreadiness Among Older Adults During COVID-19 Pandemic

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, AUGUST 3, 2020

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What The Study Did: This study uses 2018 data from the National Health and Aging Trends Study to assess how common it is for older adults in the United States to be unprepared to access video or telephone telemedicine because of disability or inexperience with technology.

Authors: Kenneth Lam, M.D., of the University of California, San Francisco, is the corresponding author.

 

(doi:10.1001/jamainternmed.2020.2671)

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Targetable Biological Mechanisms Implicated in Emergent Psychiatric Conditions Associated With SARS-CoV-2

JAMA Psychiatry

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, JULY 31, 2020

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What The Viewpoint Says: Targetable biological mechanisms implicated in emergent psychiatric conditions associated with SARS-CoV-2 infection are discussed in this Viewpoint.

Authors: Teodor T. Postolache, M.D., of the University of Maryland in Baltimore, is the corresponding author.

 

(doi:10.1001/jamapsychiatry.2020.2795)

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SARS-CoV-2 Screening Strategies for Safe Reopening of College Campuses

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, JULY 31, 2020

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: This study defines the screening performance standards for SARS-CoV-2 tests that would permit the safe return of students to U.S. residential college campuses this fall.

Authors: A. David Paltiel, Ph.D., of the Yale School of Public Health in New Haven, Connecticut, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2020.16818)

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Association Between Statewide School Closure, COVID-19 Incidence, Mortality in US

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, JULY 29, 2020

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What The Study Did: This population epidemiology study estimates associations of school closures in the U.S. and the timing of those closures in March with change in daily COVID-19 incidence and mortality through the first week of May, accounting for other existing public health interventions.

Authors: Katherine A. Auger, M.D., M.Sc., of the Cincinnati Children’s Hospital Medical Center in Ohio, is the corresponding author.

(doi:10.1001/jama.2020.14348)

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Reopening K-12 Schools During COVID-19 Pandemic

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, JULY 29, 2020

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What The Viewpoint Says: This article summarizes recommendations made in a National Academies of Sciences, Engineering, and Medicine report about how to safely reopen and operate elementary and secondary schools for the 2020-2021 school year, which emphasizes the need for partnerships with public health officials and community leaders, and for transparent communication of risks and rewards that will result from every policy decision.

Authors: Kenne A. Dibner, Ph.D., of the National Academies of Sciences, Engineering and Medicine in Washington, is the corresponding author.

(doi:10.1001/jama.2020.14745)

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Age-Related Differences in Nasopharyngeal SARS-CoV-2 Levels in Patients With COVID-19

JAMA Pediatrics

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, JULY 30, 2020

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What The Study Did: Age-related differences in nasopharyngeal SARS-CoV-2 levels in patients with mild to moderate COVID-19 were investigated in this observational study.

Authors: Taylor Heald-Sargent, M.D., Ph.D., of the Ann & Robert H. Lurie Children’s Hospital in Chicago, is the corresponding author.

 

(doi:10.1001/jamapediatrics.2020.3651)

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Risk of SARS-CoV-2 Transmission During Flexible Laryngoscopy

JAMA Otolaryngology–Head & Neck Surgery

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, JULY 30, 2020

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What The Article Says: Researchers review evidence on the risks of aerosolization and transmission of SARS-CoV-2 from patients to health care workers during endoscopy of the upper aerodigestive tract.

Authors: Josh K. Kay, M.D., of Tulane University in New Orleans, is the corresponding author.

(doi:10.1001/jamaoto.2020.1973)

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Outcomes in Radiotherapy-Treated Patients With Cancer During COVID-19

JAMA Oncology

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, JULY 30, 2020

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What The Study Did: The delivery of radiotherapy in 209 patients with cancer during the COVID-19 outbreak in Wuhan, China, is evaluated in this case series.

Authors: Conghua Xie, M.D., Ph.D., of Zhongnan Hospital of Wuhan University in Wuhan, China, and Melvin L. K. Chua, M.B.B.S., Ph.D., of the National Cancer Centre Singapore in Singapore, are the corresponding authors.

 

(doi:10.1001/jamaoncol.2020.2783)

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Changes in Opioid Use After Hip, Knee Replacement

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, JULY 30, 2020

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: Researchers looked at changes in opioid prescribing rates and level of pain control in patients who had hip or knee replacement in the U.S. from 2014 to 2017.

Authors: Rahul Shah, B.S., of the University of Texas Medical Branch in Galveston, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2020.11972)

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Face-Touching Behaviors Before, During COVID-19 Pandemic

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, JULY 29, 2020

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: Videos recorded in public transportation stations, streets and parks among the general population in China, Japan, South Korea, Western Europe and in the United States were used to analyze mask-wearing and face-touching behavior in public areas before and during the COVID-19 pandemic.

Authors: Xing Li, M.D., of the Third Affiliated Hospital of Sun Yat-sen University in Guangzhou, China, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2020.16924)

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Characteristics of Nursing Homes With Residents Infected With COVID-19

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, JULY 29, 2020

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: Characteristics of nursing homes that reported COVID-19 cases in 23 U.S. states and the District of Columbia.

Authors: Paula Chatterjee, M.D., M.P.H., of the University of Pennsylvania in Philadelphia, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2020.16930)

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Mood Homeostasis Before, During COVID-19 Lockdown

JAMA Psychiatry

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, JULY 29, 2020

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What The Study Did: Mood homeostasis (the ability to stabilize your mood with mood-modifying activities) before and during the COVID-19 lockdown among Dutch students was investigated in this observational study.

Authors: Guy M. Goodwin, M.D., of Warneford Hospital in Oxford, United Kingdom, is the corresponding author.

 

(doi:10.1001/jamapsychiatry.2020.2389)

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Gender Gap in Surgical Residencies

JAMA Surgery

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, JULY 29, 2020

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What The Study Did: Researchers identified surgical specialties with the lowest percentage of female resident physicians and looked at the changes over a decade in the percentage of women in different specialties.

Authors: Christopher L. Bennett, M.D., M.A., of Brigham and Women’s Hospital and Harvard Medical School in Boston, is the corresponding author.

 

(doi:10.1001/jamasurg.2020.2171)

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Community-Level Disparities in COVID-19 Infections, Deaths in Large US Metro Areas

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, JULY 28, 2020

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: The association of neighborhood race/ethnicity and poverty with COVID-19 infections and related deaths in urban U.S. counties are examined in this observational study.

Authors: Samrachana Adhikari, Ph.D., of the New York University Grossman School of Medicine in New York, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2020.16938)

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Assessing Inequities in COVID-19 Deaths by Race/Ethnicity Reported by CDC

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, JULY 28, 2020

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: Weighted and unweighted population data are compared to assess inequities in COVID-19 deaths by race/ethnicity as reported by the U.S. Centers for Disease Control and Prevention in this observational study.

Authors: Tori L. Cowger, M.PH., of the Harvard T.H. Chan School of Public Health in Boston, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2020.16933)

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Outcomes of Cardiovascular MRI in Patients Recovered From COVID-19

JAMA Cardiology

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, JULY 27, 2020

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What The Article Says: The presence of myocardial injury in patients recently recovered from COVID-19 are evaluated in this observational study.

Authors: Eike Nagel, M.D., of University Hospital Frankfurt in Germany, is the corresponding author.

 

(doi:10.1001/jamacardio.2020.3557)

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Association of Cardiac Infection With SARS-CoV-2 in Confirmed COVID-19 Autopsy Cases

JAMA Cardiology

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, JULY 27, 2020

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What The Study Did: The presence of SARS-CoV-2 in myocardial tissue from autopsy cases is evaluated in this observational study.

Authors: Dirk Westermann, M.D., of the University Heart and Vascular Centre Hamburg in Germany, is the corresponding author.

 

(doi:10.1001/jamacardio.2020.3551)

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Prevalence of SARS-CoV-2 Infection Among Health Care Workers in Houston

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, JULY 27, 2020

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: Rates of SARS-CoV-2 infection among asymptomatic health care workers and community residents in Texas are examined in this observational study.

Authors: Roberta L. Schwartz, Ph.D., of the Houston Methodist Academic Institute in Texas, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2020.16451)

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Estimation of Aerosol Emissions From Simulated Individuals With Asymptomatic to Moderate COVID-19

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, JULY 27, 2020

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: Viral aerosol emissions from simulated individuals with asymptomatic to moderate COVID-19 are estimated in this mathematical modeling study.

Authors: Michael Riediker, of the Swiss Centre for Occupational and Environmental Health, in Winterthur, Switzerland, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2020.13807)

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Characteristics, Strength of Evidence of COVID-19 Studies Registered on ClinicalTrials.gov

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, JULY 27, 2020

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What The Study Did: The characteristics and expected strength of evidence of COVID-19 studies registered on ClinicalTrials.gov are evaluated in this observational study.

Authors: Mintu Turakhia, M.D., M.A.S., of the Stanford University School of Medicine in Palo Alto, California, is the corresponding author.

 

(doi:10.1001/jamainternmed.2020.2904)

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How a Pandemic Could Advance Science of Early Adversity

JAMA Pediatrics

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, JULY 27, 2020

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What The Viewpoint Says: Recent advancements across disciplines relevant to early child development can be used to understand the consequences of the COVID-19 pandemic and to develop and scale empirically supported interventions for adversity-exposed children and families.

Authors: Danielle Roubinov, Ph.D., of the University of California, San Francisco, is the corresponding author.

 

(doi:10.1001/jamapediatrics.2020.2354)

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