About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Researchers in this observational study assess at what age young people ages 12 to 17 start using cigarettes.
Authors: Adriana Pérez, Ph.D., of the University of Texas Health Science Center at Houston in Austin, is the corresponding author.
(doi:10.1001/jamanetworkopen.2021.0218)
Editor’s Note: The article includes conflicts of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Researchers investigated whether home addresses recorded in the electronic medical record could be used to accurately estimate transmission risk of SARS-CoV-2 and identify risk factors for transmission.
Authors: Joshua P. Metlay, M.D., Ph.D., of Massachusetts General Hospital in Boston, is the corresponding author.
(doi:10.1001/jamanetworkopen.2021.0304)
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What The Study Did: This randomized clinical trial compares the effects of once-weekly subcutaneous semaglutide versussplacebo for weight management as an adjunct to intensive behavioral therapy with initial low-calorie diet in adults with overweight or obesity.
Authors: Thomas A. Wadden, Ph.D., of the University of Pennsylvania in Philadelphia, is the corresponding author.
(doi:10.1001/jama.2021.1831)
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What The Study Did: National COVID-19 registry data are used in this study to describe the epidemiology, clinical characteristics, complications, and hospital and postdischarge outcomes of pediatric patients with multisystem inflammatory syndrome in children (MIS-C) and to compare each in patients with severe COVID-19.
Authors: Adrienne G. Randolph, M.D., of Boston Children’s Hospital, is the corresponding author.
(doi:10.1001/jama.2021.2091)
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What The Article Says: This JAMA Insights review from Centers for Disease Control and Prevention COVID-19 Response team members presents data on the number of long-term care facilities and the numbers of residents and staff of those facilities who received first-dose vaccination through mid-January under the agency’s public-private partnership with CVS, Walgreens and Managed Health Care Associates.
Authors: Radhika Gharpure, D.V.M., M.P.H., of the COVID-19 Response at the CDC, is the corresponding author.
(doi:10.1001/jama.2021.2352)
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What The Study Did: This research letter describes the various otolaryngologic manifestations in patients 18 years or younger with pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2.
Authors: Ryan C. T. Cheong, B.Sc.(Hons), M.B.B.S., of the Great Ormond Street Hospital for Children NHS Trust in London, United Kingdom, is the corresponding author.
(doi:10.1001/jamaoto.2020.5698)
Editor’s Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Researchers in this observational study of more than 10,000 U.S. Air Force basic trainees examined whether symptoms and laboratory results on the first day of COVID-19 diagnosis are associated with development of a case cluster in a congregate setting.
Authors: Joseph E. Marcus, M.D., of the Brooke Army Medical Center at Joint Base San Antonio Fort Sam Houston, Texas, is the corresponding author.
(doi:10.1001/jamanetworkopen.2021.0202)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Data from five studies were pooled to investigate whether cognitive decline among older U.S. adults varied by sex.
Authors: Deborah A. Levine, M.D., M.P.H., of the University of Michigan in Ann Arbor, is the corresponding author.
(doi:10.1001/jamanetworkopen.2021.0169)
Editor’s Note: The article includes conflicts of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Researchers looked at whether state legalization of recreational cannabis was associated with changes in use by women before, during and after pregnancy.
Authors: Kara R. Skelton, Ph.D., of the Johns Hopkins Bloomberg School of Public Health in Baltimore, is the corresponding author.
(doi:10.1001/jamanetworkopen.2021.0138)
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What The Study Did: Researchers use a large set of clinical laboratory data linked to other clinical information such as claims to investigate the relationship between SARS-CoV-2 antibody status and subsequent nucleic acid amplification test (NAAT) results in an effort to understand how serostatus may predict risk of reinfection.
Authors: Lynne T. Penberthy, M.D., M.P.H., of the National Cancer Institute at the National Institutes of Health in Rockville, Maryland, is the corresponding author.
(doi:10.1001/jamainternmed.2021.0366)
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What The Study Did: Medicare claims and clinical data were used to estimate health care costs associated with delirium in older adults one year after major elective surgery.
Authors: Tammy T. Hshieh, M.D., M.P.H., of Brigham and Women’s Hospital in Boston, is the corresponding author.
(doi:10.1001/jamasurg.2020.7260)
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What The Study Did: This study combined the results of 12 studies with 1.8 million participants to examine the association between attention-deficit/hyperactivity disorder (ADHD) in childhood and adolescence and the subsequent risk of developing a psychotic disorder.
Authors: Mikaïl Nourredine, M.D., M.Sc., of the Hospices Civils de Lyon in Lyon, France, is the corresponding author.
(10.1001/jamapsychiatry.2020.4799)
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Researchers investigated whether children and adolescents who smoked or lived with a smoker had an increased risk of elevated blood pressure.
Authors: Rebecca V. Levy, B.M., B.Ch., M.Sc., of the Montefiore Medical Center in Bronx, New York is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.37936)
Editor’s Note: The article includes conflicts of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Researchers examined changes in trauma admissions throughout Los Angeles County during the COVID-19 pandemic in California.
Authors: Kazuhide Matsushima, M.D., of the University of Southern California in Los Angeles, is the corresponding author.
(doi:10.1001/jamanetworkopen.2021.1320)
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What The Article Says: In this narrative medicine essay, a medical school professor expresses gratitude for the caring and empathy expressed by the team caring for her mother hospitalized with COVID-19 and emphasizes the importance of humanity and compassion over facts and statistics for families physically separated from their critically ill loved ones.
Authors: Lisa M. Meeks, Ph.D., of the University of Michigan Medical School in Ann Arbor, is the author.
(doi:10.1001/jama.2021.0119)
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What The Study Did: A randomized clinical trial, this study reports that a layperson-delivered, empathy-oriented telephone call program reduced loneliness, depression and anxiety compared with the control group and improved the general mental health of participants within four weeks.
Authors: Maninder K. Kahlon, Ph.D., of the University of Texas at Austin, is the corresponding author.
(10.1001/jamapsychiatry.2021.0113)
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What The Study Did: Using COVID-19 data, this observational study looked at what are the independent associations of voluntary behavioral change and legal restrictions, such as state-mandated school closings, with the subsequent spread of the COVID-19 pandemic in the U.S.
Authors: Frederick J. Zimmerman, Ph.D., of the Fielding School of Public Health at UCLA in Los Angeles, is the corresponding author.
(doi:10.1001/jamapediatrics.2020.6371)
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What The Article Says: How parents can identify whether their teens are vaping, how to help prevent it, and what to do if their teen is addicted are discussed in this JAMA Pediatrics Patient Page.
(doi:10.1001/jamapediatrics.2020.6689)
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Authors: Jonathan E. Sevransky, M.D., M.H.S., of Emory University School of Medicine in Atlanta, is the corresponding author.
(doi:10.1001/jama.2020.24505)
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What The Study Did: This survey study looked at changes in abortion policies among states by examining legislation enacted between January 2017 and November 2020.
Authors: Phillip M. Singer, Ph.D., of the University of Utah in Salt Lake City, is the corresponding author.
(doi:10.1001/jamainternmed.2020.8781)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: This survey study compared patterns of mental health concerns, substance use and suicidal ideation during June and September of the COVID-19 pandemic and examined at-risk demographic groups.
Authors: Mark É. Czeisler, A.B., Monash University in Clayton, Victoria, Australia, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.37665)
Editor’s Note: The article includes conflicts of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Persistent symptoms among adults with COVID-19 up to nine months after illness onset were analyzed in this study.
Authors: Helen Y. Chu, M.D., M.P.H., of the University of Washington in Seattle, is the corresponding author.
(doi:10.1001/jamanetworkopen.2021.0830)
Editor’s Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Using data from completed interventional vaccine trials from 2011 to 2020, researchers examined whether racial/ethnic minority groups, females and older adults were underrepresented in U.S.-based vaccine clinical trials.
Authors: Steven A. Pergam, M.D., M.P.H., of the Fred Hutchinson Cancer Research Center in Seattle, and Julie K. Silver, M.D., of Harvard Medical School in Boston, are the corresponding authors.
(doi:10.1001/jamanetworkopen.2020.37640)
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What The Study Did: This study examined how lockdowns during the COVID-19 pandemic changed the spoken communication environments of children with cochlear implants by comparing the sounds they were exposed to before and during the resulting closures of schools and nonessential businesses.
Authors: Karen A. Gordon, Ph.D., of the University of Toronto and The Hospital for Sick Children in Toronto, Canada, is the corresponding author.
(doi:10.1001/jamaoto.2020.5496)
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What The Study Did: This is a diagnostic study that examines the accuracy and acceptability of a 3-dimensionally printed swab for identifying SARS-CoV-2.
Authors: David M. Allen, M.D., of the National University of Singapore, is the corresponding author.
(doi:10.1001/jamaoto.2020.5680)
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What The Study Did: Characteristics associated with posttraumatic stress disorder in patients after severe COVID-19 were analyzed in this observational study.
Authors: Delfina Janiri, M.D., of the Fondazione Policlinico Universitario Agostino Gemelli IRCCS in Rome, Italy, is the corresponding author.
(10.1001/jamapsychiatry.2021.0109)
Editor’s Note: The article includes conflict of interest disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Researchers examined the association between the presence of an armed guard on scene and the severity of shootings at schools kindergarten through high school.
Authors: Jillian Peterson, Ph.D., of Hamline University in St. Paul, Minnesota, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.37394)
Editor’s Note: The article includes funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Researchers examined the strength of the evidence from published meta-analyses of observational studies that looked at the association between diet and the risk of colorectal cancer.
Authors: Nathorn Chaiyakunapruk, Pharm.D., Ph.D., of the University of Utah in Salt Lake City, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.37341)
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What The Study Did: The observational study examined associations between maternal cardiovascular health during pregnancy (as measured by body mass index, blood pressure, total cholesterol level, glucose level and smoking) with the later cardiovascular health of their offspring at ages 10 to 14 years old (as measured by body mass index, blood pressure, total cholesterol level and glucose level).
Authors: Amanda M. Perak, M.D., M.S., of the Northwestern University Feinberg School of Medicine in Chicago, is the corresponding author.
(doi:10.1001/jama.2021.0247)
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Authors: Stephen P. Messier, Ph.D., J.B. of Wake Forest University in Winston-Salem, North Carolina, is the corresponding author.
(doi:10.1001/jama.2021.0411)
Editor’s Note: The article includes conflicts of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Data from four studies of children and adolescents exposed to major U.S. hurricanes were pooled to examine posttraumatic stress symptoms after those events and the factors associated with them.
Authors: Betty S. Lai, Ph.D., of Boston College in Chestnut Hill, Massachusetts, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.36682)
Editor’s Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: These findings suggest that treatment with zinc, ascorbic acid or both doesn’t affect SARS-CoV-2 symptoms.
Authors: Milind Y. Desai, M.D., M.B.A., of the Cleveland Clinic in Ohio, is the corresponding author.
(doi:10.1001/jamanetworkopen.2021.0369)
Editor’s Note: The article includes conflict of interest disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Pediatric admissions to U.S. hospitals decreased last year across an array of pediatric conditions and some may represent unmet needs in pediatric care during the COVID-19 pandemic.
Authors: Christopher M. Horvat, M.D., M.H.A., of UPMC Children’s Hospital of Pittsburgh, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.37227)
Editor’s Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: This observational study investigated the sensitivity of antibody tests to detect previous SARS-CoV-2 infection using existing clinical data across the University of California Health system.
Authors: Atul J. Butte, M.D. Ph.D., of the University of California, San Francisco, is the corresponding author.
(doi:10.1001/jamanetworkopen.2021.0337)
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What The Study Did: This case series analyzes brains from autopsies of patients who died of COVID-19 as confirmed by nucleic acid test and with severe pulmonary pathology.
Authors: David W. Nauen, M.D., Ph.D., of Johns Hopkins University in Baltimore, is the corresponding author.
(doi:10.1001/jamaneurol.2020.0225)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: This observational study assessed CRISPR-based methods for screening to detect SARS-CoV-2 among asymptomatic college students.
Authors: Carolina Arias, Ph.D., of the University of California, Santa Barbara, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.37129)
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What The Study Did: Changes in otolaryngology surgical volumes in the United States early on in the COVID-19 pandemic are described in this study.
Authors: Anirudh Saraswathula, M.D., M.S., of Johns Hopkins University School of Medicine in Baltimore, is the corresponding author.
(doi:10.1001/jamaoto.2020.5472)
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What The Viewpoint Says: How pandemic-related disruptions may adversely impact progress toward a gender-balanced workforce in academic oncology is described in this article, which also offers possible solutions to mitigate the problem in this specialty.
Authors: Reshma Jagsi, M.D., D.Phil., of the University of Michigan in Ann Arbor, is the corresponding author.
(doi:10.1001/jamaoncol.2020.7681)
Editor’s Note: The article includes conflicts of interest disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: This observational study describes differences in the number of COVID-19 deaths by nursing home racial composition and examines the factors associated with these differences.
Authors: Rebecca J. Gorges, Ph.D., of the University of Chicago, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.37431)
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What The Study Did: This article revisits the role of dermatologists in the early HIV/AIDS epidemic for the 40th anniversary of the epidemic.
Authors: Heather Milbar, M.D., M.P.H., of the University of Pennsylvania in Philadelphia, is the corresponding author.
(doi:10.1001/jamadermatol.2020.5545)
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What The Study Did: Researchers examined changes in how organ donation from deceased donors differed by race and ethnicity in the United States over time.
Authors: Dorry L. Segev, M.D., Ph.D., of the Johns Hopkins University School of Medicine in Baltimore, is the corresponding author.
(doi:10.1001/jamasurg.2020.7083)
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What The Study Did: Researchers examined how common SARS- CoV-2 infection was among migrant workers in Singapore.
Authors: Vernon J. Lee, M.B.B.S., Ph.D., of the Ministry of Health in Singapore, is the corresponding author.
(doi:10.1001/jama.2020.24071)
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What The Viewpoint Says: The missteps and miscommunications that have stymied a more effective U.S. and global response to the COVID-19 pandemic bring into sharp focus the deficiencies in governance systems of the U.S. public health and scientific institutions.
Authors: K. M. Venkat Narayan, M.D., M.Sc., of the Rollins School of Public Health and School of Medicine at Emory University in Atlanta, is the corresponding author.
(doi:10.1001/jama.2020.23479)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: To mitigate subsequent waves of COVID-19, allocating testing resources to locations of greatest need is important. Researchers in this study examined the alignment of testing to epidemic intensity in Massachusetts.
Authors: Scott Dryden-Peterson, M.D., M.Sc., of Brigham and Women’s Hospital in Boston, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.37067)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: The National Health Service in Italy provides universal coverage to citizens but because no approved drug was available for COVID-19, patients received potentially effective drugs, participated in clinical trials, accessed compassionate drug use programs or self-medicated. This study evaluated changes in drug demand during the early phase of the COVID-19 outbreak in Italy compared with the period before the outbreak.
Authors: Adriana Ammassari, M.D., of the Italian Medicines Agency in Rome, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.37060)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Researchers assessed what percentage of the Virginia population had been exposed to SARS-CoV-2 after the first wave of COVID-19 infections in the U.S.
Authors: Eric R. Houpt, M.D., of the University of Virginia in Charlottesville, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.35234)
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What The Article Says: In this essay, the authors describe a 97-year-old patient who learned to titrate condensed chicken soup like a medicine during the COVID-19 pandemic.
Authors: Yuenting Diana Kwong, M.D., M.A.S., University of California, San Francisco, is the corresponding author.
(doi:10.1001/jamainternmed.2020.8897)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: This randomized trial examined the effect of an electronic health record–linked clinical decision support tool on the use of diagnostic imaging among children and adolescents with suspected appendicitis.
Authors: Anupam B. Kharbanda, M.D., M.Sc., of Children’s Minnesota in Minneapolis, is the corresponding author.
Visual Abstract
(doi:10.1001/jamanetworkopen.2020.36344)
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What The Study Did: Salary information from faculty at U.S. medical schools was used to examine the association between the percentage of female clinicians in a medical specialty and the average and median salaries for that specialty.
Authors: Terrill Bravender, M.D., M.P.H., of the University of Michigan in Ann Arbor, is the corresponding author.
(doi:10.1001/jamapediatrics.2020.5683)
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What The Study Did: Researchers investigated the association between the use of proton pump inhibitors among children and adolescents in Sweden and the risk of asthma.
Authors: Yun-Han Wang, M.Sc., B.Pharm., of the Karolinska Institutet in Stockholm, is the corresponding author.
(doi:10.1001/jamapediatrics.2020.5710)
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What The Study Did: This observational study compared different measures of prediabetes and the risk of progression to diabetes among adults age 71 to 90.
Authors: Mary R. Rooney, Ph.D., M.P.H., of the Johns Hopkins Bloomberg School of Public Health in Baltimore, is the corresponding author.
(doi:10.1001/jamainternmed.2020.8774)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Researchers examined admission rates for heroin treatment by race, age, and sex from 2000 to 2017 at state-regulated programs.
Authors: Elodie C. Warren, M.P.H., of the Bureau of Alcohol and Drug Use Prevention, Care and Treatment in Long Island City, New York, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.36640)
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What The Study Did: Researchers in this randomized clinical trial investigated whether nasopharyngeal application of povidone iodine could reduce the viral load of patients with nonsevere COVID-19 symptoms.
Authors: Olivier Mimoz, M.D., Ph.D., University Hospital of Poitiers in Poitiers, France, is the corresponding author.
(doi:10.1001/jamaoto.2020.5490)
Editor’s Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Researchers estimated the rate of nurse burnout in the United States and the factors associated with leaving or considering leaving their jobs due to burnout.
Authors: Megha K. Shah, M.D., M.Sc., of the Emory University School of Medicine in Atlanta, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.36469)
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What The Study Did: This randomized clinical trial looked at changes in levels of the hormone estradiol in men with hormone receptor–positive breast cancer after three months of treatment with endocrine therapies.
Authors: Sibylle Loibl, M.D., Ph.D., of the German Breast Group in Neu-Isenburg, Germany, is the corresponding author.
Visual Abstract:
(doi:10.1001/jamaoncol.2020.7442)
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What The Study Did: Data from the Centers for Disease Control and Prevention were used to look at changes in emergency department visits for mental health, suicide attempts, drug and opioid overdoses and outcomes of violence before and during the COVID-19 pandemic.
Authors: Kristin M. Holland, Ph.D., M.P.H., of the Centers for Disease Control and Prevention in Atlanta, is the corresponding author.
(10.1001/jamapsychiatry.2020.4402)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: COVID-19 outcomes including hospitalization and in-hospital death were compared between people living with or without diagnosed HIV in New York State.
Authors: Eli S. Rosenberg, Ph.D., of the State University of New York in Rensselaer, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.37069)
Editor’s Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Researchers assessed potential changes in suicide rates associated with the COVID-19 pandemic in Japan through November 2020 and performed analyses by sex, age group, and occupational status.
Authors: Peter Ueda, M.D., Ph.D., of the University of Tokyo Graduate School of Medicine in Japan, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.37378)
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What The Study Did: Researchers assessed the proportion of international entrants to China with asymptomatic SARS-CoV-2 infection. Since April, people entering China via air, sea or land have been mandatorily tested for SARS-CoV-2 infection by PCR test at border checkpoints. Those who have tested positive have been hospitalized in isolation and those who have tested negative have been quarantined for 14 days at centralized facilities and then retested on day 13.
Authors: Zunyou Wu, M.D., Ph.D., of the Chinese Center for Disease Control and Prevention in Beijing, is the corresponding author.
(doi:10.1001/jama.2020.23942)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Researchers used near real-time social media data to capture the public’s changing COVID-19–related attitudes when former President Trump was infected.
Authors: Sean D. Young, Ph.D., of the University of California, Irvine, is the corresponding author.
(doi:10.1001/jamanetworkopen.2021.0101)
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What The Study Did: Researchers looked at changes in the rate of deaths associated with the use of illicit (such as cocaine) and medical stimulants in the United States from 2010 to 2017.
Authors: Joshua C. Black, Ph.D., of Rocky Mountain Poison & Drug Safety in Denver, is the corresponding author.
(doi:10.1001/jamainternmed.2020.7850)
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What The Study Did: County-level mortality and economic data were used to investigate the association between changes in economic prosperity and rates of cardiovascular mortality among middle-age U.S. adults from 2010 to 2017.
Authors: Sameed Ahmed M. Khatana, M.D., M.P.H., of the University of Pennsylvania in Philadelphia, is the corresponding author.
(doi:10.1001/jama.2020.26141)
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What The Study Did: This report summarizes frequency and patterns of concussions and repetitive head impacts over the course of several seasons among college football players who wore sensors in their helmets.
Authors: Michael McCrea, Ph.D., of the Medical College of Wisconsin in Milwaukee, is the corresponding author.
(doi:10.1001/jamaneurol.2020.5193)
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What The Study Did: Maternally derived antibodies are a key element of neonatal immunity. This study examined the association between maternal and neonatal SARS-CoV-2-specific antibody concentrations because understanding the dynamics of maternal antibody responses to SARS-CoV-2 infection during pregnancy and subsequent transplacental antibody transfer can inform neonatal management as well as maternal vaccination strategies.
Authors: Scott E. Hensley, Ph.D., of the University of Pennsylvania in Philadelphia, and Karen M. Puopolo, M.D., Ph.D., of the Children’s Hospital of Philadelphia, are the corresponding authors.
(doi:10.1001/jamapediatrics.2021.0038)
Editor’s Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Researchers investigated the association between county-level social risk factors and COVID-19 cases and deaths, as well as weekly changes in cumulative cases and mortality, using publicly available data sets as of July 29, 2020.
Authors: Renuka Tipirneni, M.D., M.Sc., of the University of Michigan in Ann Arbor, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.36462)
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EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, FEBRUARY 2, 2021
Media advisory: To contact the U.S. Preventive Services Task Force, email the Media Coordinator at Newsroom@USPSTF.net or call 301-951-9203. The full report and related articles are linked to this news release.
Bottom Line: The U.S. Preventive Services Task Force (USPSTF) recommends against screening for asymptomatic carotid artery stenosis in the general adult population. Carotid artery stenosis is the narrowing of arteries that supply blood to the brain. This recommendation applies to adults without a history of transient ischemic attack, stroke or other neurologic signs or symptoms related to the carotid arteries. Although asymptomatic carotid artery stenosis is a risk factor for stroke, it causes a relatively small proportion of strokes. The USPSTF routinely makes recommendations about the effectiveness of preventive care services and this statement is consistent with its 2014 recommendation.
(doi:10.1001/jama.2020.26988)
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Note: More information about the U.S. Preventive Services Task Force, its process, and its recommendations can be found on the newsroom page of its website.
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Researchers examined if the use of diagnostic imaging for children receiving care in pediatric emergency departments in the United States differs by race and ethnicity.
Authors: Jennifer R. Marin, M.D., M.Sc., of the University of Pittsburgh School of Medicine, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.33710)
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