Association Between Exposure Characteristics, Risk for COVID-19 Infection Among Health Care Workers With/Without Pfizer-BioNTech Vaccination

JAMA Network Open


Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.


What The Study Did: This case-control study found that exposure to SARS-CoV-2-positive household members was a risk factor associated with infection among vaccinated health care workers. Household exposure is usually longer and closer than casual exposure or exposure at work and does not include masking or distancing, thus exposing one to a higher infectious dose and being more contagious.

Authors: Yonatan Oster, M.D., of the Hadassah Hebrew University Medical Center in Jerusalem, Israel, is the corresponding author.



Editor’s Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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