Racial, Ethnic Differences in Deceased Organ Donation

JAMA Surgery

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, FEBRUARY 10, 2021

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What The Study Did: Researchers examined changes in how organ donation from deceased donors differed by race and ethnicity in the United States over time.

Authors: Dorry L. Segev, M.D., Ph.D., of the Johns Hopkins University School of Medicine in Baltimore, is the corresponding author.

 

(doi:10.1001/jamasurg.2020.7083)

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SARS-CoV-2 Infection Among Migrant Workers in Singapore

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, FEBRUARY 9, 2021

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What The Study Did: Researchers examined how common SARS- CoV-2 infection was among migrant workers in Singapore.

Authors: Vernon J. Lee, M.B.B.S., Ph.D., of the Ministry of Health in Singapore, is the corresponding author.

 

(doi:10.1001/jama.2020.24071)

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COVID-19 Pandemic as Opportunity to Ensure More Successful Future for Science, Public Health

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, FEBRUARY 9, 2021

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What The Viewpoint Says: The missteps and miscommunications that have stymied a more effective U.S. and global response to the COVID-19 pandemic bring into sharp focus the deficiencies in governance systems of the U.S. public health and scientific institutions.

Authors: K. M. Venkat Narayan, M.D., M.Sc., of the Rollins School of Public Health and School of Medicine at Emory University in Atlanta, is the corresponding author.

 

(doi:10.1001/jama.2020.23479)

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Disparities in SARS-CoV-2 Testing in Massachusetts During COVID-19 Pandemic

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, FEBRUARY 9, 2021

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: To mitigate subsequent waves of COVID-19, allocating testing resources to locations of greatest need is important. Researchers in this study examined the alignment of testing to epidemic intensity in Massachusetts.

Authors: Scott Dryden-Peterson, M.D., M.Sc., of Brigham and Women’s Hospital in Boston, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2020.37067)

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Comparison of Demand for Drugs for COVID-19 Treatment, Other Drugs Early in Pandemic in Italy

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, FEBRUARY 8, 2021

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: The National Health Service in Italy provides universal coverage to citizens but because no approved drug was available for COVID-19, patients received potentially effective drugs, participated in clinical trials, accessed compassionate drug use programs or self-medicated. This study evaluated changes in drug demand during the early phase of the COVID-19 outbreak in Italy compared with the period before the outbreak.

Authors: Adriana Ammassari, M.D., of the Italian Medicines Agency in Rome, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2020.37060)

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Assessment of SARS-CoV-2 and Risk Factors Associated With COVID-19 Among Outpatients in Virginia

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, FEBRUARY 8, 2021

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: Researchers assessed what percentage of the Virginia population had been exposed to SARS-CoV-2 after the first wave of COVID-19 infections in the U.S.

Authors: Eric R. Houpt, M.D., of the University of Virginia in Charlottesville, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2020.35234)

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Outpatient Dietary Management of Electrolyte Disorders During COVID-19

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, FEBRUARY 8, 2021

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What The Article Says: In this essay, the authors describe a 97-year-old patient who learned to titrate condensed chicken soup like a medicine during the COVID-19 pandemic.

Authors: Yuenting Diana Kwong, M.D., M.A.S., University of California, San Francisco, is the corresponding author.

 

(doi:10.1001/jamainternmed.2020.8897)

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Imaging Use in Children With Suspected Appendicitis

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, FEBRUARY 9, 2021

Media advisory: The full study is linked to this news release. A visual abstract is below.

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: This randomized trial examined the effect of an electronic health record–linked clinical decision support tool on the use of diagnostic imaging among children and adolescents with suspected appendicitis.

Authors: Anupam B. Kharbanda, M.D., M.Sc., of Children’s Minnesota in Minneapolis, is the corresponding author.

 

Visual Abstract

 

(doi:10.1001/jamanetworkopen.2020.36344)

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Examining Association Between Percentage of Women in Medical Specialties, Salaries

JAMA Pediatrics

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, FEBRUARY 8, 2021

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What The Study Did: Salary information from faculty at U.S. medical schools was used to examine the association between the percentage of female clinicians in a medical specialty and the average and median salaries for that specialty.

Authors: Terrill Bravender, M.D., M.P.H., of the University of Michigan in Ann Arbor, is the corresponding author.

 

(doi:10.1001/jamapediatrics.2020.5683)

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Proton Pump Inhibitor Use by Children, Risk of Asthma

JAMA Pediatrics

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, FEBRUARY 8, 2021

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What The Study Did: Researchers investigated the association between the use of proton pump inhibitors among children and adolescents in Sweden and the risk of asthma.

Authors: Yun-Han Wang, M.Sc., B.Pharm., of the Karolinska Institutet in Stockholm, is the corresponding author.

 

(doi:10.1001/jamapediatrics.2020.5710)

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Risk of Progression to Diabetes Among Older Adults With Prediabetes

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, FEBRUARY 8, 2021

Media advisory: The full study and commentary are linked to this news release.

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What The Study Did: This observational study compared different measures of prediabetes and the risk of progression to diabetes among adults age 71 to 90.

Authors: Mary R. Rooney, Ph.D., M.P.H., of the Johns Hopkins Bloomberg School of Public Health in Baltimore, is the corresponding author.

 

(doi:10.1001/jamainternmed.2020.8774)

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Heroin Treatment Admissions in US

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, FEBRUARY 5, 2021

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: Researchers examined admission rates for heroin treatment by race, age, and sex from 2000 to 2017 at state-regulated programs.

Authors: Elodie C. Warren, M.P.H., of the Bureau of Alcohol and Drug Use Prevention, Care and Treatment in Long Island City, New York, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2020.36640)

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Povidone Iodine Mouthwash, Gargle, Nasal Spray to Reduce Nasopharyngeal Viral Load in Patients With COVID-19

JAMA Otolaryngology–Head & Neck Surgery

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, FEBRUARY 4, 2021

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What The Study Did: Researchers in this randomized clinical trial investigated whether nasopharyngeal application of povidone iodine could reduce the viral load of patients with nonsevere COVID-19 symptoms.

Authors: Olivier Mimoz, M.D., Ph.D., University Hospital of Poitiers in Poitiers, France, is the corresponding author.

 

(doi:10.1001/jamaoto.2020.5490)

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https://jamanetwork.com/journals/jamaotolaryngology/fullarticle/10.1001/jamaoto.2020.5490?guestAccessKey=c60aee4d-d4da-4df2-ad4e-9482ac6400c5&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=020421

Factors, Rate of Nurse Burnout in US

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, FEBRUARY 4, 2021

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: Researchers estimated the rate of nurse burnout in the United States and the factors associated with leaving or considering leaving their jobs due to burnout.

Authors: Megha K. Shah, M.D., M.Sc., of the Emory University School of Medicine in Atlanta, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2020.36469)

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Effectiveness of Endocrine Therapy for Breast Cancer in Men

JAMA Oncology

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, FEBRUARY 4, 2021

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What The Study Did: This randomized clinical trial looked at changes in levels of the hormone estradiol in men with hormone receptor–positive breast cancer after three months of treatment with endocrine therapies.

Authors: Sibylle Loibl, M.D., Ph.D., of the German Breast Group in Neu-Isenburg, Germany, is the corresponding author.

Visual Abstract:

 

(doi:10.1001/jamaoncol.2020.7442)

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Emergency Department Visits for Mental Health, Overdose and Violence Before, During COVID-19 Pandemic

JAMA Psychiatry

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, FEBRUARY 3, 2021

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What The Study Did: Data from the Centers for Disease Control and Prevention were used to look at changes in emergency department visits for mental health, suicide attempts, drug and opioid overdoses and outcomes of violence before and during the COVID-19 pandemic.

Authors: Kristin M. Holland, Ph.D., M.P.H., of the Centers for Disease Control and Prevention in Atlanta, is the corresponding author.

 

(10.1001/jamapsychiatry.2020.4402)

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COVID-19 Outcomes Among Individuals Living With, Without HIV in New York State

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, FEBRUARY 3, 2021

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: COVID-19 outcomes including hospitalization and in-hospital death were compared between people living with or without diagnosed HIV in New York State.

Authors: Eli S. Rosenberg, Ph.D., of the State University of New York in Rensselaer, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2020.37069)

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Assessment of Suicide in Japan During COVID-19 Pandemic Compared With Previous Years

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, FEBRUARY 2, 2021

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: Researchers assessed potential changes in suicide rates associated with the COVID-19 pandemic in Japan through November 2020 and performed analyses by sex, age group, and occupational status.

Authors: Peter Ueda, M.D., Ph.D., of the University of Tokyo Graduate School of Medicine in Japan, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2020.37378)

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Asymptomatic SARS-CoV-2 Infections Among People Entering China

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, FEBRUARY 2, 2021

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What The Study Did: Researchers assessed the proportion of international entrants to China with asymptomatic SARS-CoV-2 infection. Since April, people entering China via air, sea or land have been mandatorily tested for SARS-CoV-2 infection by PCR test at border checkpoints. Those who have tested positive have been hospitalized in isolation and those who have tested negative have been quarantined for 14 days at centralized facilities and then retested on day 13.

Authors: Zunyou Wu, M.D., Ph.D., of the Chinese Center for Disease Control and Prevention in Beijing, is the corresponding author.

 

(doi:10.1001/jama.2020.23942)

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Public Attitudes About COVID-19 in Response to President Trump’s Social Media Posts

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, FEBRUARY 1, 2021

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: Researchers used near real-time social media data to capture the public’s changing COVID-19–related attitudes when former President Trump was infected.

Authors: Sean D. Young, Ph.D., of the University of California, Irvine, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2021.0101)

Editor’s Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Stimulant-Associated Deaths in US

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, FEBRUARY 1, 2021

Media advisory: The full study is linked to this news release.

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What The Study Did: Researchers looked at changes in the rate of deaths associated with the use of illicit (such as cocaine) and medical  stimulants in the United States from 2010 to 2017.

Authors: Joshua C. Black, Ph.D., of Rocky Mountain Poison & Drug Safety in Denver, is the corresponding author.

 

(doi:10.1001/jamainternmed.2020.7850)

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Changes in Economic Prosperity, Cardiovascular Mortality

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, FEBRUARY 2, 2021

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What The Study Did: County-level mortality and economic data were used to investigate the association between changes in economic prosperity and rates of cardiovascular mortality among middle-age U.S. adults from 2010 to 2017.

Authors: Sameed Ahmed M. Khatana, M.D., M.P.H., of the University of Pennsylvania in Philadelphia, is the corresponding author.

 

(doi:10.1001/jama.2020.26141)

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Concussions, Repetitive Head Impacts Among College Football Players

JAMA Neurology

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, FEBRUARY 1, 2021

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What The Study Did: This report summarizes frequency and patterns of concussions and repetitive head impacts over the course of several seasons among college football players who wore sensors in their helmets.

Authors: Michael McCrea, Ph.D., of the Medical College of Wisconsin in Milwaukee, is the corresponding author.

 

(doi:10.1001/jamaneurol.2020.5193)

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Assessment of Maternal, Neonatal Cord Blood SARS-CoV-2 Antibodies, Placental Transfer Ratios

JAMA Pediatrics

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, JANUARY 29, 2021

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What The Study Did: Maternally derived antibodies are a key element of neonatal immunity. This study examined the association between maternal and neonatal SARS-CoV-2-specific antibody concentrations because understanding the dynamics of maternal antibody responses to SARS-CoV-2 infection during pregnancy and subsequent transplacental antibody transfer can inform neonatal management as well as maternal vaccination strategies.

Authors: Scott E. Hensley, Ph.D., of the University of Pennsylvania in Philadelphia, and Karen M. Puopolo, M.D., Ph.D., of the Children’s Hospital of Philadelphia, are the corresponding authors.

 

(doi:10.1001/jamapediatrics.2021.0038)

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Association of Social, Demographic Factors With COVID-19 Cases, Death Rates in US

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, JANUARY 29, 2021

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: Researchers investigated the association between county-level social risk factors and COVID-19 cases and deaths, as well as weekly changes in cumulative cases and mortality, using publicly available data sets as of July 29, 2020.

Authors: Renuka Tipirneni, M.D., M.Sc., of the University of Michigan in Ann Arbor, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2020.36462)

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USPSTF Recommends Against Screening for Asymptomatic Carotid Artery Stenosis in General Population

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, FEBRUARY 2, 2021

Media advisory: To contact the U.S. Preventive Services Task Force, email the Media Coordinator at Newsroom@USPSTF.net or call 301-951-9203. The full report and related articles are linked to this news release.

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Bottom Line: The U.S. Preventive Services Task Force (USPSTF) recommends against screening for asymptomatic carotid artery stenosis in the general adult population. Carotid artery stenosis is the narrowing of arteries that supply blood to the brain. This recommendation applies to adults without a history of transient ischemic attack, stroke or other neurologic signs or symptoms related to the carotid arteries. Although asymptomatic carotid artery stenosis is a risk factor for stroke, it causes a relatively small proportion of strokes. The USPSTF routinely makes recommendations about the effectiveness of preventive care services and this statement is consistent with its 2014 recommendation.

(doi:10.1001/jama.2020.26988)

 

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.

Note: More information about the U.S. Preventive Services Task Force, its process, and its recommendations can be found on the newsroom page of its website.

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Racial, Ethnic Differences in Diagnostic Imaging at Children’s Hospitals Emergency Departments

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, JANUARY 29, 2021

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: Researchers examined if the use of diagnostic imaging for children receiving care in pediatric emergency departments in the United States differs by race and ethnicity.

Authors: Jennifer R. Marin, M.D., M.Sc., of the University of Pittsburgh School of Medicine, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2020.33710)

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Association Between Unemployment Insurance, Food Insecurity Among People Who Lost Jobs During COVID-19 Pandemic in US

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, JANUARY 29, 2021

Media advisory: The full study and commentary are linked to this news release.

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: This study investigated how unemployment insurance and a $600 per week federal supplement to unemployment insurance were associated with food insecurity among people in low- and middle-income households who lost jobs during the COVID-19 pandemic.

Authors: Julia Raifman, Sc.D., of the Boston University School of Public Health, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2020.35884)

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Outcomes of COVID-19 Among Hospitalized Health Care Workers in North America

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, JANUARY 28, 2021

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: This study finds that being a health care worker isn’t associated with poorer outcomes among patients hospitalized with COVID-19.

Authors: Nauzer Forbes, M.D., M.Sc., of the University of Calgary in Canada, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2020.35699)

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Conditions Among Patients With COVID-19 Four Months After Hospital Discharge

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, JANUARY 27, 2021

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: This study among patients in Italy suggests that despite virological recovery, a sizable proportion of patients with COVID-19 experienced respiratory, functional or psychological conditions months after hospital discharge.

Authors: Mattia Bellan, M.D., Ph.D., of Università del Piemonte Orientale in Novara, Italy, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2020.36142)

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Examining Oncology Clinical Trials Launched Before, During COVID-19 Pandemic

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, JANUARY 27, 2021

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: Researchers evaluated the association between the pandemic and clinical research and development by studying the initiation of oncology clinical trials over time.

Authors: Elizabeth B. Lamont, M.D., M.S., M.MSc., of Acorn AI by Medidata, a Dassault Systèmes Company, in Boston, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2020.36353)

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Association of Psychiatric Disorders With Mortality Among Patients With COVID-19

JAMA Psychiatry

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, JANUARY 27, 2021

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What The Study Did: In this observational study of about 7,300 adults with laboratory-confirmed COVID-19 in a New York health system, a schizophrenia spectrum diagnosis was associated with an increased risk of death after adjusting for demographic and medical risk factors. Mood and anxiety disorders weren’t associated with increased risk of mortality.

Authors: Donald C. Goff, M.D., of New York University Langone Medical Center in New York, is the corresponding author.

 

(doi:10.1001/jamapsychiatry.2020.4442)

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Prevalence, Risk Factors Associated With Self-Reported Psychological Distress Among Children, Adolescents During COVID-19 Pandemic in China

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, JANUARY 26, 2021

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: Survey data from school-age children and adolescents in Guangdong province, China, were used to assess self-reported psychological distress associated with the COVID-19 pandemic.

Authors: Chichen Zhang, M.D., and Ruibin Zhang, Ph.D., of Southern Medical University in Guangzhou, and Xuefeng Yi, M.D., of the Health Publicity and Education Center of Guangdong Province, all in China, are the corresponding authors.

 

(doi:10.1001/jamanetworkopen.2020.35487)

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Seasonal Respiratory Virus Activity Before, After Statewide COVID-19 Shelter-in-Place Order in Northern California

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, JANUARY 25, 2021

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: The association of a shelter-in-place order with lower rates of seasonal respiratory viral activity was examined in this study.

Authors: Elizabeth Partridge, M.D., of the University of California at Davis School of Medicine in Sacramento, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2020.35281)

Editor’s Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Association of Smoking With COVID-19 Outcomes

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, JANUARY 25, 2021

Media advisory: The full study is linked to this news release.

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What The Study Did: The results of this study suggest that cumulative exposure to cigarette smoke is an independent risk factor for hospital admission and death from COVID-19.

Authors: Katherine E. Lowe, M.Sc., of the Cleveland Clinic Lerner College of Medicine of Case Western Reserve in Cleveland, is the corresponding author.

 

(doi:10.1001/jamainternmed.2020.8360)

Editor’s Note: The article includes conflicts of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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SARS-CoV-2 Infection in Children, Their Parents in Southwest Germany

JAMA Pediatrics

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, JANUARY 22, 2021

Media advisory: The full study and editorial are linked to this news release.

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What The Study Did: In this observational study, the spread of SARS-CoV-2 infection during a period of lockdown in southwest Germany was particularly low in children ages 1 to 10 years old. Overall, this large SARS-CoV-2 prevalence study in children is instructive for how ad hoc mass testing provides the basis for rational political decision-making in a pandemic setting.

Authors: Burkhard Tönshoff, M.D., of the University Children’s Hospital in Heidelberg, Germany, and Klaus-Michael Debatin, M.D., of Ulm University Medical Center in Ulm, Germany, are the corresponding authors.

 

(doi:10.1001/jamapediatrics.2021.0001)

Editor’s Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Effect of Bamlanivimab as Monotherapy or in Combination With Etesevimab on Viral Load in Patients With Mild to Moderate COVID-19

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, JANUARY 21, 2021

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What The Study Did: This randomized clinical trial compares the effects of three doses of bamlanivimab monotherapy (700 vs 2,800 vs 7,000 mg) vs combination bamlanivimab and etesevimab vs placebo on change in day 11 severe acute respiratory syndrome coronavirus 2 viral load in patients with mild to moderate COVID-19.

Authors: Daniel M. Skovronsky, M.D., Ph.D., of Eli Lilly and Company in Indianapolis, is the corresponding author.

 

(doi:10.1001/jama.2021.0202)

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Allergic Reactions Including Anaphylaxis After Receipt of 1st Dose of Pfizer-BioNTech COVID-19 Vaccine

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, JANUARY 21, 2021

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What The Study Did: This JAMA Insights review provides clinical details of anaphylactic reactions reported to and verified by the Centers for Disease Control and Prevention in the first week of use of the Pfizer-BioNTech COVID-19 vaccine in the United States.

Authors: Tom Shimabukuro, M.D., M.P.H., M.B.A., of the CDC in Atlanta, is the corresponding author.

 

(doi:10.1001/jama.2021.0600)

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Safe, Efficient Performance of Open Tracheostomies in Patients With COVID-19

JAMA Otolaryngology–Head & Neck Surgery

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, JANUARY 21, 2021

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What The Study Did: Researchers demonstrate a technique of tracheostomy that minimizes aerosolization risks while creating a tight seal around the tracheostomy tube.

Authors: Oluwafunmilola T. Okuyemi, M.D., M.S.C.I., of the University of Nevada, Las Vegas School of Medicine, is the corresponding author.

 

(doi:10.1001/jamaoto.2020.4432)

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Presence of SARS-CoV-2 RNA in Cornea of Patients With COVID-19

JAMA Ophthalmology

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, JANUARY 7, 2021

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What The Study Did: Evidence of SARS-CoV-2 RNA in human corneas was examined in this study.

Authors: Maria Casagrande, M.D., of the University Medical Center Hamburg-Eppendorf in Hamburg, Germany, is the corresponding author.

 

(doi:10.1001/jamaophthalmol.2020.6339)

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Hand Sanitizer–Induced Ocular Injury

JAMA Ophthalmology

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, JANUARY 21, 2021

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What The Study Did: The cases of two children with eye injuries after unintentional contact between alcohol-based hand rubs and the eye are described in this observation.

Authors: Sonam Yangzes, M.S., of the Grewal Eye Institute in Chandigarh, India, is the corresponding author.

 

(doi:10.1001/jamaophthalmol.2020.6351)

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Pediatric Eye Injuries, Hand Sanitizers During COVID-19 Pandemic

JAMA Ophthalmology

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, JANUARY 21, 2021

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What The Study Did: An increase in pediatric cases of alcohol-based hand sanitizer eye exposure was assessed in this study, which also described the severity of ocular lesions and their management.

Authors: Gilles C. Martin, M.D., M.Sc., of theRothschild Foundation Hospital in Paris, is the corresponding author.

 

(doi:10.1001/jamaophthalmol.2020.6346)

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Racial/Ethnic Disparities in Unintentional EMS-Attended Opioid Overdoses During COVID-19 Pandemic

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, JANUARY 21, 2021

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: Associations of the COVID-19 pandemic with overdoses among racial/ethnic groups in Philadelphia are described in this observational study.

Authors: Utsha G. Khatri, M.D., of the Perelman School of Medicine at the University of Pennsylvania in Philadelphia, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2020.34878)

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Association of Obstructive Sleep Apnea With Risk of Male Infertility

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, JANUARY 21, 2021

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: A large health insurance database in Taiwan was used to investigate whether obstructive sleep apnea is a risk factor in male infertility and if treatment for sleep apnea is associated with risk.

Authors: Ping-Ying Chang, M.D., Ph.D., and Wu-Chien Chien, Ph.D., of the National Defense Medical Center in Taipei, Taiwan, are the corresponding authors.

 

(doi:10.1001/jamanetworkopen.2020.31846)

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Suicide-Related Internet Searches During Early Stages of COVID-19 Pandemic

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, JANUARY 21, 2021

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: This study monitored suicide-related internet search rates during the early stages of the COVID-19 pandemic in the United States and researchers report searches for suicide decreased during that time. Although this study cannot independently confirm that changes in search rates were caused by changes in population-level suicide rates, it showed that COVID-19 may have been inversely associated with population suicide trends between March and July 2020.

Authors: John W. Ayers, Ph.D., M.A., of theUniversity of California San Diego, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2020.34261)

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Suicide Deaths During COVID-19 Stay-at-Home Advisory in Massachusetts

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, JANUARY 21, 2021

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: Researchers assembled suicide death data for people 10 and older from January 2015 through May 2020 in this observational study and they report stable rates of suicide deaths during the COVID-19 stay-at-home advisory in Massachusetts, a finding that paralleles others following ecological disasters.

Authors: Jeremy Samuel Faust, M.D., M.S., of Brigham and Women’s Hospital and Harvard Medical School in Boston, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2020.34273)

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Reports of Forgone Medical Care Among US Adults During Initial Phase of COVID-19 Pandemic

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, JANUARY 21, 2021

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: This study estimated the frequency of reported forgone medical care because of the COVID-19 pandemic from March to mid-July 2020, including missed doses of prescription medications, forgone preventive and other general medical care, mental health care and elective surgeries, as well as reasons for forgoing care.

Authors: Kelly E. Anderson, M.P.P., of the Johns Hopkins Bloomberg School of Public Health in Baltimore, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2020.34882)

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Association of Social, Economic Inequality With COVID-19 Across US Counties

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, JANUARY 20, 2021

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: This investigation analyzed U.S. county-level associations of income inequality, racial/ethnic composition and political attributes with COVID-19 cases and mortality.

Author: Tim F. Liao, Ph.D., of the University of Illinois at Urbana-Champaign, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2020.34578)

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Factors Associated With U.S. Public Motivation to Use, Distribute COVID-19 Self-Tests

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, JANUARY 20, 2021

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: Researchers examined individuals’ motivation to self-test and to distribute self-test kits given the urgent need to increase COVID-19 testing coverage and contact tracing.

Author: Cedric Bien-Gund, M.D., of the Perelman School of Medicine at the University of Pennsylvania in Philadelphia, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2020.34001)

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Associations of Government-Mandated Closures, Restrictions With Mobility, SARS-CoV-2 Infections in Nigeria

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, JANUARY 20, 2021

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: This observational study examined how COVID-19–related government-mandated closures and restrictions were associated with changes in mobility and the spread of COVID-19 in Nigeria.

Author: Daniel O. Erim, M.D., Ph.D., M.Sc., of Parexel International in Durham, North Carolina, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2020.32101)

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Outcomes of Hospitalized Women Giving Birth With, Without COVID-19

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, JANUARY 15, 2021

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What The Study Did: Clinical characteristics and outcomes such as preterm birth, preeclampsia, blood clots and death were compared among hospitalized women with and without COVID-19 who gave birth between April and November 2020.

Authors: Scott D. Solomon, M.D., of Brigham and Women’s Hospital in Boston, is the corresponding author.

 

(doi:10.1001/jamainternmed.2020.9241)

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Comparing Accuracy of Saliva Sample, Nasal Swab for Detection of SARS-CoV-2

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, JANUARY 15, 2021

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What The Study Did: Researchers compared the accuracy of nucleic acid amplification testing of saliva samples with nasal swab samples for the diagnosis of COVID-19 by combining the results of 16 studies with nearly 6,000 patients.

Authors: Guillaume Butler-Laporte, M.D., of Royal Victoria Hospital in Montréal, is the corresponding author.

 

(doi:10.1001/jamainternmed.2020.8876)

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Effect of Discontinuing vs Continuing ACEIs, ARBs in Patients Admitted With COVID-19

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, JANUARY 19, 2021

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What The Study Did: Among patients hospitalized with mild to moderate COVID-19 and who were taking angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin II receptor blockers (ARBs) before hospital admission, there was no significant difference in the average number of days alive and out of the hospital for those assigned to discontinue versus continue these medications in this randomized clinical trial. These findings do not support routinely discontinuing ACEIs or ARBs among patients hospitalized with mild to moderate COVID-19 if there is an indication for treatment.

Authors: Renato D. Lopes, M.D., Ph.D.,of the Duke Clinical Research Institute in Durham, North Carolina, is the corresponding author.

Visual Abstract:

(doi:10.1001/jama.2020.25864)

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Association of Home Quarantine, Mental Health Among Teenagers in Wuhan, China, During COVID-19 Pandemic

JAMA Pediatrics

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, JANUARY 19, 2021

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What The Study Did: When quarantine was imposed in Wuhan, China, because of COVID-19, all schools were closed. This study aimed to investigate the how common depression and anxiety were and their associations with lifestyle changes among adolescents in Wuhan.

Authors: Jiwei Wang, Ph.D., of Fudan University in Shanghai, China, is the corresponding author.

 

(doi:10.1001/jamapediatrics.2020.5499)

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Epidemiology of COVID-19 in US ICE Detention Facilities

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, JANUARY 19, 2021

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: COVID-19 among people detained by U.S. Immigration and Customs Enforcement is described and compared with the U.S. population.

Author: Kathryn M. Nowotny, Ph.D., of the University of Miami in Florida, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2020.34409)

Editor’s Note: The article includes funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Association of ICU Patient Load, Demand With Mortality Rates in VA Hospitals During COVID-19 Pandemic

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, JANUARY 19, 2021

Media advisory: The full study and commentary are linked to this news release.

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: Whether COVID-19 mortality was associated with COVID-19 intensive care unit strain was investigated in this observational study.

Author: Dawn M. Bravata, M.D., of Health Services Research and Development, Department of Veterans Affairs in Indianapolis, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2020.34266)

Editor’s Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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USPSTF Recommendation on Interventions to Quit Smoking

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, JANUARY 19, 2021

Media advisory: To contact the U.S. Preventive Services Task Force, email the Media Coordinator at Newsroom@USPSTF.net or call 301-951-9203. The full report and related articles are linked to this news release.

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Bottom Line: The U.S. Preventive Services Task Force (USPSTF) recommends that clinicians ask all adults about tobacco use, advise them to stop using it, and provide behavioral interventions and pharmacotherapy for quitting to nonpregnant adults. The recommendation for pregnant adults is largely the same, except the USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of pharmacotherapy interventions for tobacco cessation in those who are pregnant. The USPSTF routinely makes recommendations about the effectiveness of preventive care services and this statement is consistent with the 2015 recommendation and incorporates newer evidence and language in the field of tobacco cessation, including new evidence on the harms of e-cigarettes.

 

(doi:10.1001/jama.2020.25019)

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Note: More information about the U.S. Preventive Services Task Force, its process, and its recommendations can be found on the newsroom page of its website.

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Socioeconomic Disparities in Patient Use of Telehealth During COVID-19 Surge

JAMA Otolaryngology–Head & Neck Surgery

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, JANUARY 14, 2021

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What The Study Did: Which demographic and socioeconomic factors were associated with patient participation in telehealth during the COVID-19 pandemic surge was examined in this observational study.

Authors: Ilaaf Darrat, M.D., M.B.A., of the Henry Ford Hospital in Detroit, is the corresponding author.

 

(doi:10.1001/jamaoto.2020.5161)

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Progression of Myopia in Children After COVID-19 Home Confinement

JAMA Ophthalmology

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, JANUARY 14, 2021

Media advisory: The full article is linked to this news release.

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What The Study Did: Researchers investigated the association of home confinement during the COVID-19 outbreak with myopia (nearsightedness) development in school-age children in China.

Authors: Xuehan Qian, M.D., Ph.D., of Tianjin Medical University Eye Hospital in Tianjin, China, is the corresponding author. This is an open access article distributed under the terms of the CC-BY License. © 2021 Wang J et al. JAMA Ophthalmology.

 

(doi:10.1001/jamaophthalmol.2020.6239)

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Cancer Screening Tests, Cancer Diagnoses During COVID-19 Pandemic

JAMA Oncology

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, JANUARY 14, 2021

Media advisory: The full article is linked to this news release.

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What The Study Did: The number of patients undergoing cancer screening tests and of subsequent cancer diagnoses during the COVID-19 pandemic in the largest health care system in the northeastern United States was assessed in this study.

Authors: Toni K. Choueiri, M.D., of the Dana-Farber Cancer Institute and Quoc-Dien Trinh, M.D., of Brigham and Women’s Hospital in Boston, are the corresponding authors.

 

(doi:10.1001/jamaoncol.2020.7600)

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Comparing Reactions of Flu Vaccines in Older Adults

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, JANUARY 14, 2021

Media advisory: The full study is linked to this news release. A visual abstract is below.

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

 

What The Study Did: Researchers in this randomized clinical trial compared injection-site pain and other reactions among adults age 65 and older who received flu vaccines.

Author: Kenneth E. Schmader, M.D., of the Duke University School of Medicine in Durham, North Carolina, is the corresponding author.

 

Visual Abstract

(doi:10.1001/jamanetworkopen.2020.31266)

Editor’s Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Here’s a link to provide your readers free access to the full-text article

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Here’s a link to provide your readers free access to the full-text article

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