About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: In this observational study, data are used to assess the association of demographic and clinical characteristics with severe COVID-19 illness among hospitalized U.S. pediatric patients with COVID-19.
Authors: Alyson B. Goodman, M.D., of the COVID-19 Response Team at the Centers for Disease Control and Prevention in Atlanta, is the corresponding author.
(doi:10.1001/jamanetworkopen.2021.5298)
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What The Study Did: This Viewpoint discusses potential associations between functional neurological disorder and COVID-19 vaccinations.
Authors: David L. Perez, M.D., M.MSc., of Massachusetts General Hospital and Harvard Medical School in Boston, is the corresponding author.
(doi:10.1001/jamaneurol.2021.1042)
Editor’s Note: The article includes conflicts of interest disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Researchers analyzed changes in out-of-pocket health care expenses in the United States during the last two decades.
Authors: Amit Jain, M.D., of the Johns Hopkins University School of Medicine in Baltimore, is the corresponding author.
(doi:10.1001/jamanetworkopen.2021.5499)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
Visual Abstract
Authors: Louisa Gilbert, Ph.D., of the Columbia University School of Social Work in New York, is the corresponding author.
(doi:10.1001/jamanetworkopen.2021.5226)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: This analysis evaluated in-hospital mortality rates for patients with SARS-CoV-2 infection over time and factors associated with changes were examined
Authors: Lyn Finelli, Dr.P.H., M.S., of Merck Research Labs in North Wales, Pennsylvania, is the corresponding author.
(doi:10.1001/jamanetworkopen.2021.6556)
Editor’s Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: This survey study uses self-reported data from a national study of veterans to assess the association of symptoms of posttraumatic stress disorder with posttraumatic psychological growth (these are positive psychological changes such as an appreciation of life and personal growth) among U.S. veterans during the COVID-19 pandemic.
Authors: Robert H. Pietrzak, Ph.D., M.P.H., of the U.S. Department of Veterans Affairs National Center for Posttraumatic Stress Disorder and the VA Connecticut Healthcare System in West Haven, is the corresponding author.
(doi:10.1001/jamanetworkopen.2021.4972)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: This observational study identifies and quantifies the association of race/ethnicity, sex and income, as well as state-specific lockdown measures, with six well-being dimensions in the United States.
Authors: Leigh C. Hamlet, B.S., of the University of Washington in Seattle, is the corresponding author.
(doi:10.1001/jamanetworkopen.2021.7373)
Editor’s Note: The article includes funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: In this observational study of 3.4 million live births in 2018, criminalizing immigrant policies were associated with higher rates of preterm birth for Black women born outside the U.S., while inclusive immigrant policies were associated with lower preterm birth for all women born outside the U.S.,particularly White women born outside the U.S.
Authors: May Sudhinaraset, Ph.D., of the Jonathan and Karin Fielding School of Public Health at the University of California, Los Angeles, is the corresponding author.
(doi:10.1001/jamanetworkopen.2021.4482)
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What The Study Did: This case series examines whether maternal SARS-CoV-2 is associated with outcomes in the eyes of their newborns.
Authors: Olívia Pereira Kiappe, M.D., M.Sc., of Universidade Federalde São Paulo in Brazil, is the corresponding author.
(doi:10.1001/jamaophthalmol.2021.1088)
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What The Study Did: Researchers report on the observation of a newly associated mucocutaneous eruption in a pediatric patient with confirmed SARS-CoV-2 infection
Authors:Zachary E. Holcomb, M.D., of Boston Children’s Hospital, is the corresponding author.
(doi:10.1001/jamadermatol.2021.0385)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Researchers projected to the year 2040 what will become the most common and deadly cancers in the United States.
Authors: Lola Rahib, Ph.D., of Cancer Commons in Mountain View, California, is the corresponding author.
(doi:10.1001/jamanetworkopen.2021.4708)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Questionnaire responses were compared to examine whether transgender children and teens experience significantly higher levels of anxiety and depression than their cisgender peers.
Authors: Dominic J. Gibson, Ph.D., of the University of Washington in Seattle, is the corresponding author.
(doi:10.1001/jamanetworkopen.2021.4739)
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What The Study Did: The clinical and other characteristics of multisystem inflammatory syndrome in children in the United States, a condition that occurs in association with the COVID-19 pandemic, are described in this study.
Authors: Ermias D. Belay, M.D., of the Centers for Disease Control and Prevention in Atlanta, is the corresponding author.
(doi:10.1001/jamapediatrics.2021.0630)
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What The Study Did: Researchers compared the effectiveness of case-based (including contact tracing and quarantine) and population-based (including social distancing and facial masking) interventions for COVID-19 containment in Taiwan, one of the few countries with initial success in COVID-19 control without strict lockdown or school closure.
Authors: Hsien-Ho Lin, M.D., Sc.D., of National Taiwan University in Taipei, Taiwan, is the corresponding author.
(doi:10.1001/jamainternmed.2021.1644)
Editor’s Note: The article includes conflicts of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: A model to prioritize vaccination was developed that estimates the risk of SARS-CoV-2–related death among enrollees in the Veterans Affairs health care system.
Authors: George N. Ioannou, B.M.B.Ch., M.S., of the Veterans Affairs Puget Sound Healthcare System in Seattle, is the corresponding author.
(doi:10.1001/jamanetworkopen.2021.4347)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: This study investigated the role of droplet or contact transmission in the development of Kawasaki disease in Japan during the COVID-19 state of emergency. Kawasaki disease primarily affects children and is characterized by fever and swelling in the walls of some blood vessels.
Authors: Toshiro Hara, M.D., Ph.D., of the Fukuoka Children’s Hospital in Fukuoka, Japan, is the corresponding author.
(doi:10.1001/jamanetworkopen.2021.4475)
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What The Study Did: The 30-day incidence of outpatient and hospital-associated blood clots following SARS-CoV-2 testing among adults in a large health system was examined in this study.
Authors: Nareg H. Roubinian, M.D., of Kaiser Permanente Northern California in Oakland, is the corresponding author.
(doi:10.1001/jamainternmed.2021.0488)
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What The Study Did: A clinical risk assessment tool developed in China was tested with a group of patients in Spain to evaluate its ability to predict critical illness among patients hospitalized with COVID-19 in Europe.
Authors: Oscar Moreno-Perez, M.D., Ph.D., of the Alicante General University Hospital–Alicante Institute of Sanitary and Biomedical Research in Alicante, Spain, is the corresponding author.
(doi:10.1001/jamainternmed.2021.0491)
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What The Study Did: This study updates an analysis of deaths in the United States in 2020, including deaths due to COVID-19 as well as all other causes.
Authors: Steven H. Woolf, M.D., M.P.H., of the Virginia Commonwealth University School of Medicine in Richmond, is the corresponding author.
(doi:10.1001/jama.2021.5199)
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What The Study Did: Researchers estimated and projected the number of children in the United States affected by the death of a parent from COVID-19.
Authors: Rachel Kidman, Ph.D., of Stony Brook University in Stony Brook, New York, is the corresponding author.
(doi:10.1001/jamapediatrics.2021.0161)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Electronic health record data were used to examine whether the transition to remote cardiology clinic visits during COVID-19 is associated with disparities in patient use of care, diagnostic test ordering and medication prescribing.
Authors: Neal Yuan, M.D., of Cedars-Sinai Medical Center in Los Angeles, is the corresponding author.
(doi:10.1001/jamanetworkopen.2021.4157)
Editor’s Note: The article includes conflicts of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Researchers investigated the association of sociodemographic factors and blood group type with the risk of SARS-CoV-2 infection and severity of COVID-19.
Authors: Jeffrey L. Anderson, M.D., of the Intermountain Medical Center Heart Institute in Salt Lake City, is the corresponding author.
(doi:10.1001/jamanetworkopen.2021.7429)
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What The Article Says: This JAMA Insights Clinical Update from the CDC’s COVID-19 Response Team discusses the association of changes in COVID-19 case rates and death rates with implementation of state-issued mask mandates and allowance of any on-premises restaurant dining.
Authors: Gery P. Guy Jr, Ph.D., M.P.H., of the Centers for Disease Control and Prevention in Atlanta, is the corresponding author.
(doi:10.1001/jama.2021.5455)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: This survey study examined the career development, productivity, childcare needs and likelihood of leaving the workforce among employees at an academic medical center during the COVID-19 pandemic.
Authors: Angela Fagerlin, Ph.D., of the University of Utah in Salt Lake City, is the corresponding author.
(doi:10.1001/jamanetworkopen.2021.3997)
Editor’s Note: The article includes conflicts of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Researchers compared rates of health maintenance organization (HMO) enrollment, by race and ethnicity, for children with commercial and public coverage with the use of national survey data.
Authors: Alon Peltz, M.D., M.B.A., M.H.S., of Harvard Medical School in Boston, is the corresponding author.
(doi:10.1001/jamanetworkopen.2021.4162)
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Authors: Jie Wang, M.D., Ph.D., of the Chinese Academy of Medical Sciences and Peking Union Medical College in Beijing, is the corresponding author.
(doi:10.1001/jamaoncol.2021.0366)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: This observational study examined death and hospital readmission rates of patients with COVID-19 pneumonia after being discharged to home or quarantine housing with supplemental home oxygen.
Authors: Brad Spellberg, M.D., of the Los Angeles County + University of Southern California Medical Center in Los Angeles, is the corresponding author.
(doi:10.1001/jamanetworkopen.2021.3990)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Researchers assessed changes in the number of views of articles published in three leading medical journals since the start of the COVID-19 pandemic.
Authors: Andrew J. Giustini, M.D., Ph.D., of the Stanford University School of Medicine in Stanford, California, is the corresponding author.
(doi:10.1001/jamanetworkopen.2021.6459)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Nationally representative data were used to look at whether systolic and diastolic blood pressure levels among children and adolescents in the United States have changed during the past 20 years.
Authors: Shakia T. Hardy, Ph.D., of the University of Alabama at Birmingham, is the corresponding author.
(doi:10.1001/jamanetworkopen.2021.3917)
Editor’s Note: The article includes conflicts of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Researchers compared mortality and severe adverse events in this systematic review and meta-analysis of 52 studies that evaluated clinical outcomes among nearly 102,000 patients with COVID-19 who did and didn’t receive angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin receptor blockers (ARBs).
Authors: Vassilios S. Vassiliou, M.B.B.S., Ph.D., of the University of East Anglia in Norwich, United Kingdom is the corresponding author.
(doi:10.1001/jamanetworkopen.2021.3694)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: This study identified risk factors for SARS-CoV-2 incidence, hospitalization and death among nursing home residents in the United States.
Authors: James S. Goodwin, M.D., of the University of Texas Medical Branch in Galveston, is the corresponding author.
(doi:10.1001/jamanetworkopen.2021.6315)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: This study documented how perception of risk of infection and severe complications from COVID-19 were associated with underlying reported health.
Authors: Robert F. Schoeni, Ph..D., of the University of Michigan in Ann Arbor, is the corresponding author.
(doi:10.1001/jamanetworkopen.2021.3984)
Editor’s Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: In this decision analytical modelling study, researchers investigated the association of school reopening or closure with new and cumulative COVID-19 case numbers compared with other community-based interventions.
Authors: David Naimark, M.D., M.Sc., of the Sunnybrook Health Sciences Centre in Toronto, Canada, is the corresponding author.
(doi:10.1001/jamanetworkopen.2021.3793)
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What The Study Did: This study sought to assess dermatologists’ perceptions of and experiences with teledermatology in the context of the COVID-19 pandemic and new regulatory changes including parity in reimbursements between video and in-person visits.
Authors: Jules B. Lipoff, M.D., of the Perelman School of Medicine at the University of Pennsylvania in Philadelphia, is the corresponding author.
(doi:10.1001/jamadermatol.2021.0195)
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What The Study Did: Researchers investigated COVID-19 vaccine intentions among racially and ethnically diverse samples of health workers and the general population in the San Francisco Bay area.
Authors: Kevin Grumbach, M.D., of the San Francisco General Hospital and University of California, San Francisco, is the corresponding author.
(doi:10.1001/jamainternmed.2021.1445)
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What The Study Did: This article discusses possible pathogenic mechanisms of brain dysfunction in patients with COVID-19.
Authors: Maura Boldrini, M.D., Ph.D., of the New York State Psychiatric Institute, Columbia University Irving Medical Center in New York, is the corresponding author.
(doi:10.1001/jamapsychiatry.2021.0500)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: This comparative effectiveness study investigates how the COVID-19 pandemic is associated with the benefits and risks of standard radiation therapy in simulated patients.
Authors: Rifaquat Rahman, M.D., of the Dana-Farber/Brigham and Women’s Cancer Center in Boston, is the corresponding author.
(doi:10.1001/jamanetworkopen.2021.3304)
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What The Study Did: Insurance claims were used to assess patterns of telehealth use across surgical specialties before and during the COVID-19 pandemic.
Authors: Grace F.Chao, M.D., M.Sc., of the National Clinician Scholars Program at the University of Michigan and Veterans Affairs Ann Arbor in Michigan, is the corresponding author.
(doi:10.1001/jamasurg.2021.0979)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: This comparative effectiveness research study that included a high proportion of non-White individuals assesses whether remdesivir administered alone or with corticosteroids is associated with time to clinical improvement or time to death in patients hospitalized with confirmed COVID-19.
Authors: Brian T. Garibaldi, M.D,. M.E.H.P., of the Johns Hopkins University School of Medicine in Baltimore, is the corresponding author.
(doi:10.1001/jamanetworkopen.2021.3071)
Editor’s Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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What The Study Did: Researchers evaluated the association between a recent diagnosis of mild cognitive impairment or dementia and the risk of attempting suicide among older adults.
Authors: Amy L Byers, Ph.D., M.P.H., of the University of California, San Francisco, is the corresponding author.
(doi:10.1001/jamapsychiatry.2021.0150)
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What The Study Did: This survey study investigated the frequency and nature of sexist and racial/ethnic microaggressions against female and racial/ethnic–minority surgeons and anesthesiologists and the association with physician burnout.
Authors: Neha T. Sudol, M.D., of the Southern California Permanente Medical Group in Irvine, is the corresponding author.
(doi:10.1001/jamasurg.2021.0265)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Employees of a health care system were surveyed on the eve of vaccine distribution to encourage them to receive a COVID-19 vaccine, assess their intentions to do so and understand reasons for hesitancy.
Authors: Michelle N. Meyer, Ph.D., J.D., Center for Translational Bioethics and Health Care Policy at the Geisinger Health System in Danville, Pennsylvania, is the corresponding author.
(doi:10.1001/jamanetworkopen.2021.5344)
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: This study of working-age people enrolled in private health plans from March 2019 through June 2020 documented patterns of care at the onset of COVID-19.
Authors: Jonathan P. Weiner, Dr.P.H., Johns Hopkins Bloomberg School of Public Health in Baltimore, is the corresponding author.
(doi:10.1001/jamanetworkopen.2021.2618)
Editor’s Note: The article includes funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Researchers investigated representation of Black Americans in clinical trials of cardiovascular drugs approved by the U.S. Food and Drug Administration between 2006 and 2020.
Authors: Jiarui Li, M.D., of the Chinese Academy of Medical Sciences and Peking Union Medical College in Beijing, China, is the corresponding author.
(doi:10.1001/jamanetworkopen.2021.2640)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: This study examined whether the quantity and quality of antibodies against SARS-CoV-2 were different among children, adolescents and young adults.
Authors: Zhen Zhao, Ph.D., of Weill Cornell Medicine in New York, is the corresponding author.
(doi:10.1001/jamanetworkopen.2021.4302)
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Authors: Domenica Rubino, M.D., of the Washington Center for Weight Management in Arlington, Virginia, is the corresponding author.
(doi:10.1001/jama.2021.3224)
Editor’s Note: The article includes conflicts of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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What The Study Did:This economic evaluation estimates the budget impact and affordability of a gene therapy for severe sickle cell disease from the perspective of U.S. Medicaid programs with the highest prevalence of sickle cell disease.
Authors: Patrick DeMartino, M.D., of Oregon Health & Science University in Portland, is the corresponding author.
(doi:10.1001/jamapediatrics.2020.7140)
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What The Study Did: Rates and significance of incidental findings in brain magnetic resonance imaging (MRI) in children were investigated in this study.
Authors: Leo Sugrue, M.D., Ph.D., of the University of California, San Francisco, is the corresponding author.
(doi:10.1001/jamaneurol.2021.0306)
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What The Study Did: Researchers investigated associations of maternal hypertensive disorders of pregnancy and the risk of autism spectrum disorders, attention-deficit/hyperactivity disorder and intellectual disability in children as well as overall cognitive performance.
Authors: Judith S. Brand, Ph.D., of Örebro University in Örebro, Sweden, is the corresponding author.
(doi:10.1001/jamapediatrics.2020.6856)
Editor’s Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Researchers investigated whether shelter-in-place orders in the United States during the early weeks of the COVID-19 pandemic were associated with changes in body weight among adults.
Authors: Gregory M. Marcus, M.D., M.A.S., of the University of California, San Francisco, is the corresponding author.
(doi:10.1001/jamanetworkopen.2021.2536)
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What The Study Did: This study estimates how many older adults in the United States who need equipment to help with bathing and toileting don’t have it and the factors associated with not having such equipment.
Authors: Kenneth Lam, M.D., University of California, San Francisco, is the corresponding author.
(doi:10.1001/jamainternmed.2021.0204)
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EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, MARCH 23, 2021
Media advisory: To contact the U.S. Preventive Services Task Force, email the Media Coordinator at Newsroom@USPSTF.net or call 301-951-9203. The full report and related articles are linked to this news release.
Bottom Line: The U.S. Preventive Services Task Force (USPSTF) concludes that current evidence is insufficient to make a recommendation about screening for hearing loss in asymptomatic adults 50 and older. Nearly 16% of U.S. adults 18 and over report difficulty hearing. Hearing loss has been associated with an increased risk of falls, hospitalizations, social isolation and cognitive decline. The USPSTF routinely makes recommendations about the effectiveness of preventive care services and this recommendation is similar to its 2012 statement.
(doi:10.1001/jama.2021.2566)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.
Note: More information about the U.S. Preventive Services Task Force, its process, and its recommendations can be found on the newsroom page of its website.
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Researchers examined if differences in vitamin D levels greater than levels traditionally considered sufficient (30 ng/mL) are associated with having test results positive for COVID-19 in White and in Black individuals.
Authors: David O. Meltzer, M.D., Ph.D., of the University of Chicago, is the corresponding author.
(doi:10.1001/jamanetworkopen.2021.4117)
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What The Study Did: This analysis examined how patients with multiple sclerosis who have COVID-19 fare and what patient and disease characteristics are associated with worse outcomes.
Authors: Amber Salter, Ph.D., of Washington University in St Louis, is the corresponding author.
(doi:10.1001/jamaneurol.2021.0688)
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Authors: Jun J. Mao, M.D., M.S.C.E., of the Memorial Sloan Kettering Cancer Center in New York, is the corresponding author.
(doi:10.1001/jamaoncol.2021.0310)
Editor’s Note: The article includes conflicts of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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What The Article Says: An oncologist reflects on how advising patients with cancer about travel during a pandemic requires a nuanced consideration of benefit and risk, especially when considering lost opportunities when prognosis is limited.
Authors: Christopher E. Jensen, M.D., of the University of North Carolina School of Medicine in Chapel Hill, is the corresponding author.
(doi:10.1001/jamaoncol.2021.0125)
Editor’s Note: The article includes conflicts of interest disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Researchers examined whether state medical and recreational cannabis laws were associated with changes in rates of self-harm and assault injuries.
Authors: Keith Humphreys, Ph.D., of Stanford University in Stanford, California, is the corresponding author.
(doi:10.1001/jamanetworkopen.2021.1955)
Editor’s Note:Editor’s Note: The article includes conflicts of interest disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Racial and ethnic disparities in very preterm birth and preterm birth among 8,026 women were similar during the first wave of the COVID-19 pandemic in New York City compared with the same period the year prior in this observational study.
Authors: Teresa Janevic, Ph.D., M.P.H., of the Icahn School of Medicine at Mount Sinai in New York, is the corresponding author.
(doi:10.1001/jamanetworkopen.2021.1816)
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