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Mucocutaneous Manifestations of Multisystem Inflammatory Syndrome in Children During COVID-19 Pandemic
JAMA Dermatology
EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, DECEMBER 9, 2020
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What The Study Did: This case series describes the mucocutaneous findings seen in children with multisystem inflammatory syndrome in children during the height of the COVID-19) pandemic in New York City.
Authors: Vikash S. Oza, M.D., of the New York University Grossman School of Medicine in New York, is the corresponding author.
(doi:10.1001/jamadermatol.2020.4372)
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Shedding Light on Opioid Exposure, COVID-19 and Health Disparities
JAMA Psychiatry
EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, DECEMBER 9, 2020
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What The Viewpoint Says: This Viewpoint describes the planned Healthy Brain and Child Development Study, which will investigate the associations of parental substance abuse, COVID-19 and exposure to health disparities with their children’s health and well-being.
Authors: Michelle P. Freund, Ph.D., of the National Institute on Drug Abuse at the National Institutes of Health in Bethesda, Maryland, is the corresponding author.
(doi:10.1001/jamapsychiatry.2020.3803)
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Variation by States in Heart Transplant Outcomes
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, DECEMBER 9, 2020
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Data from the United Network for Organ Sharing database were used to examine variation at the state level in waitlist and transplant outcomes among patients listed for heart transplantation from 2011 to 2016.
Authors: Alexandros Briasoulis, M.D., Ph.D., of the University of Iowa Hospitals and Clinics in Iowa City, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.28459)
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Examining Association of Physician Burnout With Suicidal Thoughts, Medical Errors
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, DECEMBER 9, 2020
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Physicians were surveyed to examine the association between burnout and thoughts of suicide and self-reported medical errors after accounting for depression.
Authors: Mickey T. Trockel, M.D., Ph.D., of the Stanford University School of Medicine in Stanford, California, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.28780)
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Children, Teens With Depression, Risk of Subsequent Health Problems, Premature Death
JAMA Psychiatry
EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, DECEMBER 9, 2020
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What The Study Did: Researchers investigated whether children and adolescents diagnosed with depression had an increased risk of subsequent physical health problems and premature death in this observational study.
Authors: Sarah E. Bergen, Ph.D., of the Karolinska Institutet in Stockholm, Sweden, is the corresponding author.
(doi:10.1001/jamapsychiatry.2020.3786)
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Comparing Long-Term Outcomes of Weight-Loss Surgeries
JAMA Surgery
EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, DECEMBER 9, 2020
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What The Study Did: Long-term follow-up of a randomized clinical trial was conducted to compare weight loss and quality of life among patients with morbid obesity who had laparoscopic sleeve gastrectomy or laparoscopic Roux-en-Y gastric bypass surgery.
Authors: Paulina Salminen, M.D., Ph.D., of Turku University Hospital in Turku, Finland, is the corresponding author.
(doi:10.1001/jamasurg.2020.5666)
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Safety of Delaying Surgery for High-Risk Prostate Cancer
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, DECEMBER 8, 2020
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Considering when health care resources need to be prioritized during special times, such as the COVID-19 pandemic, researchers in this observational study looked at whether delaying radical prostatectomy surgery for up to six months for high-risk prostate cancer was associated with worse outcomes.
Authors: Leilei Xia, M.D., of the University of Pennsylvania Perelman School of Medicine in Philadelphia, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.28320)
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Nursing Researcher’s Experience in COVID-19 Vaccine Trial
JAMA Internal Medicine
EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, DECEMBER 7, 2020
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What The Article Says: This perspective is that of a nursing researcher turned volunteer in a COVID-19 vaccine trial. She considers the experience of study participants and how clinicians will need to prepare their patients for the vaccine’s possible adverse effects.
Authors: Kristen R. Choi, Ph.D., R.N., of the University of California, Los Angeles, is the corresponding author.
(doi:10.1001/jamainternmed.2020.7087)
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Evaluation of Rooming-in Practice for Babies Born to Mothers With SARS-CoV-2 Infection in Italy
JAMA Pediatrics
EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, DECEMBER 7, 2020
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What The Study Did: The findings of this study suggest that mother-to-infant transmission of SARS-CoV-2 during rooming-in practice is rare, provided adequate droplet and contact precautions are taken.
Authors: Lorenza Pugni, M.D., Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Neonatology and NICU, in Milan, Italy, is the corresponding author.
(doi:10.1001/jamapediatrics.2020.5086)
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Number of Childhood, Adolescent Vaccinations Administered Before, After COVID-19 Outbreak in Colorado
JAMA Pediatrics
EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, DECEMBER 7, 2020
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What The Study Did: Using data from the Colorado Immunization Information System, this study suggests vaccination uptake in children and adolescents has decreased in Colorado since the start of the COVID-19 outbreak in that state.
Authors: Sean O’Leary, M.D., M.P.H., of the University of Colorado Anschutz Medical Campus in Aurora, is the corresponding author.
(doi:10.1001/jamapediatrics.2020.4733)
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COVID-19 Pandemic Health Disparities and Pediatric Health Care
JAMA Pediatrics
EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, DECEMBER 7, 2020
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What The Article Says: Telehealth is a vital strategy to bridge pediatric physical and mental health care gaps, potentially reducing health care disparities.
Authors: Deepa U. Menon, M.B.B.S., and Harolyn M.E. Belcher, M.D., M.H.S., of the Kennedy Krieger Institute and Johns Hopkins University School of Medicine in Baltimore, Maryland, are the authors.
(doi:10.1001/jamapediatrics.2020.5097)
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Mental Health Themes in Popular Rap Music
JAMA Pediatrics
EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, DECEMBER 7, 2020
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What The Study Did: Lyrics from the most popular rap songs from the past two decades were analyzed to see if references to anxiety, depression, suicide and mental health struggles have become more common.
Authors: Francesca R. Dillman Carpentier, Ph.D., of the University of North Carolina at Chapel Hill, is the corresponding author.
(doi:10.1001/jamapediatrics.2020.5155)
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Pediatric Appendix Perforation Rate at Children’s Hospital During COVID-19 Pandemic
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, DECEMBER 4, 2020
Media advisory: The full study is linked to this news release.
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: This observational study assessed the rate of appendix perforations during the COVID-19 pandemic at a children’s hospital compared with 2019.
Authors: Rick Place, M.D., M.H.A., of Inova Fairfax Medical Campus in Falls Church, Virginia, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.27948)
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Assessment of Racial/Ethnic Disparities in Hospitalization, Mortality in Patients With COVID-19 in New York City
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, DECEMBER 4, 2020
Media advisory: The full study is linked to this news release.
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: COVID-19 outcomes based on race and ethnicity were compared in this observational study of patients in a large health system in New York City, and the association of any disparities with coexisting medical conditions and neighborhood characteristics also was assessed.
Authors: Gbenga Ogedegbe, M.D., M.P.H., of the NYU Grossman School of Medicine in New York, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.26881)
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E-Cigarette Use by Youth, Young Adults Before, During COVID-19 Pandemic
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, DECEMBER 3, 2020
Media advisory: The full study and commentary are linked to this news release.
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: This survey study examines changes in the use of e-cigarettes by those 24 years old and younger during the COVID-19 pandemic.
Authors: Bonnie Halpern-Felsher, Ph.D., of Stanford University in Palo Alto, California, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.27572)
Editor’s Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Overdose-Related Cardiac Arrests Observed by Emergency Medical Services During COVID-19 Pandemic
JAMA Psychiatry
EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, DECEMBER 3, 2020
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What The Study Did: Emerging changes in overdose-related cardiac arrests in the U.S. during the COVID-19 pandemic are described in this observational study using a large national emergency medical services database.
Authors: Joseph Friedman, M.P.H., of the University of California, Los Angeles, is the corresponding author.
(doi:10.1001/jamapsychiatry.2020.4218)
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US State Government Crisis Standards of Care Guidelines
JAMA Oncology
EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, DECEMBER 3, 2020
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What The Study Did: State crisis standards of care (CSC) guidelines in the U.S. allocate scarce health care resources among patients, and this study examined the implications of these guidelines for patients with cancer, including allocation methods, cancer-related categorical exclusions and deprioritizations, and provisions for blood products and palliative care.
Authors: Gregory A. Abel, M.D., M.P.H., of the Dana-Farber Cancer Institute in Boston, is the corresponding author.
(doi:10.1001/jamaoncol.2020.6159)
Editor’s Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Race/Ethnicity Among Children With COVID-19-Associated Multisystem Inflammatory Syndrome
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, NOVEMBER 30, 2020
Media advisory: The full study is linked to this news release.
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: The distribution of race/ethnicity among cases of COVID-19]-associated multisystem inflammatory syndrome in children reported to the New York City Department of Health and Mental Hygiene is described in this observational study.
Authors: Ellen H. Lee, M.D., of the New York City Department of Health and Mental Hygiene in Long Island City, New York, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.30280)
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Unemployment Insurance, Health-Related Social Needs, Health Care Access, Mental Health During COVID-19 Pandemic
JAMA Internal Medicine
EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, NOVEMBER 30, 2020
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What The Study Did: This observational study assessed whether receiving unemployment insurance is associated with lower health-related social needs, better health care access and better mental health during the COVID-19 pandemic.
Authors: Seth A. Berkowitz, M.D., M.P.H., of the University of North Carolina at Chapel Hill, is the corresponding author.
(doi:10.1001/jamainternmed.2020.7048)
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Racial Disparities in Dementia in US
JAMA Neurology
EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, NOVEMBER 30, 2020
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What The Study Did: Nationally representative data were used to examine if racial disparities in the occurrence of dementia in the United States changed from 2000 to 2016.
Authors: Melinda C. Power, Sc.D., of George Washington University in Washington, D.C., is the corresponding author.
(doi:10.1001/jamaneurol.2020.4471)
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Alzheimer Disease, Related Dementias and Risk of Financial Errors
JAMA Internal Medicine
EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, NOVEMBER 30, 2020
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What The Study Did: Researchers linked administrative health care and demographic data from Medicare to the Federal Reserve Bank of New York/Equifax Consumer Credit Panel to characterize the financial presentation of Alzheimer disease and related dementias before and after diagnosis.
Authors: Lauren Hersch Nicholas, Ph.D., M.P.P., of the Johns Hopkins Bloomberg School of Public Health and the Johns Hopkins University School of Medicine in Baltimore, is the corresponding author.
(doi:10.1001/jamainternmed.2020.6432)
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Estimated SARS-CoV-2 Seroprevalence in US
JAMA Internal Medicine
EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, NOVEMBER 24, 2020
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What The Study Did: This study reports what proportion of people across 52 U.S. jurisdictions had detectable antibodies against SARS-CoV-2 from July to September 2020.
Authors: Kristina L. Bajema, M.D., M.Sc., of the U.S. Centers for Disease Control and Prevention in Atlanta, is the corresponding author.
(doi:10.1001/jamainternmed.2020.7976)
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Characteristics of Patients With Chilblain-like Lesions During COVID-19 Pandemic
JAMA Dermatology
EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, NOVEMBER 25, 2020
Media advisory: The full study is linked to this news release.
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What The Study Did: A range of skin-related manifestations, including chilblain-like lesions, have been described in association with SARS-CoV-2 infection during the COVID-19 pandemic. The aim of this case series of 40 patients was to evaluate patients presenting with chilblain-like lesions to characterize this condition occurring during the COVID-19 pandemic.
Authors: Thierry Passeron, M.D., Ph.D., of the Université Côte d’Azur, Centre Hospitalier Universitaire de Nice in Nice, France, is the corresponding author.
(doi:10.1001/jamadermatol.2020.4324)
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Perceptions of Patients With Cancer During COVID-19 Crisis
JAMA Oncology
EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, NOVEMBER 25, 2020
Media advisory: The full article is linked to this news release.
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What The Study Did: This observational study assessed how Dutch patients with cancer perceive care and well-being during the COVID-19 crisis.
Authors: Lonneke V. van de Poll-Franse, Ph.D., of the Netherlands Comprehensive Cancer Organisation in Utrecht, the Netherlands, is the corresponding author.
(doi:10.1001/jamaoncol.2020.6093)
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Effect of Trauma Center Opening in Chicago
JAMA Surgery
EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, NOVEMBER 25, 2020
Media advisory: The full study is linked to this news release.
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What The Study Did: How opening a new trauma center in Chicago was associated with a change in racial, ethnic and socioeconomic disparities in timely access to trauma care was examined in this observational study.
Authors: Ali B. Abbasi, M.D., M.Sci., M.Phil., of the University of California, San Francisco, is the corresponding author.
(doi:10.1001/jamasurg.2020.4998)
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Assessment of 136K Pediatric Patients Tested for SARS-CoV-2 in US
JAMA Pediatrics
EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, NOVEMBER 23, 2020
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What The Study Did: This observational study used electronic health records for almost 136,000 pediatric patients in the United States to describe testing for SARS-CoV-2 and SARS-CoV-2 infection and COVID-19 illness.
Authors: L. Charles Bailey, M.D., Ph.D., of Children’s Hospital of Philadelphia is the corresponding author.
(doi:10.1001/jamapediatrics.2020.5052)
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Nutritional Quality of Foods, Beverages in Movies
JAMA Internal Medicine
EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, NOVEMBER 23, 2020
Media advisory: The full study is linked to this news release.
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What The Study Did: The nutritional quality of foods and beverages depicted in 250 top-grossing movies in the United States from 1994 to 2018 was compared with dietary recommendations in this study.
Authors: Bradley P. Turnwald, Ph.D., of Stanford University in Stanford, California, is the corresponding author.
(doi:10.1001/jamainternmed.2020.5421)
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Magnet Swallowing By Children After Changes in Federal Regulations
JAMA
EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, NOVEMBER 24, 2020
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What The Study Did: Researchers looked at changes in the rates of emergency department visits for children who swallowed small high-powered magnets over a period of change in federal regulations of these magnets.
Authors: Michael R. Flaherty, D.O., of MassGeneral Hospital for Children in Boston, is the corresponding author.
(doi:10.1001/jama.2020.19153)
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USPSTF Recommendation on Behavioral Counseling to Promote Healthy Diet, Activity for Adults With Risk of CVD
JAMA
EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, NOVEMBER 24, 2020
Media advisory: To contact the U.S. Preventive Services Task Force, email the Media Coordinator at Newsroom@USPSTF.net or call 202-572-2044. The full report and related articles are linked to this news release.
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Bottom Line: The U.S. Preventive Services Task Force (USPSTF) recommends offering or referring adults with cardiovascular disease risk factors to behavioral counseling interventions to promote a healthy diet and physical activity. Adults who adhere to national guidelines for a healthy diet and physical activity have a lower risk of cardiovascular disease and death than those who do not. The USPSTF routinely makes recommendations about the effectiveness of preventive care services. This statement is mostly consistent with its 2014 recommendation, although it no longer includes adults with impaired glucose tolerance or type 2 diabetes because this population is now included in a separate USPSTF recommendation.
(doi:10.1001/jama.2020.21749)
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Note: More information about the U.S. Preventive Services Task Force, its process, and its recommendations can be found on the newsroom page of its website.
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Pregnancy Outcomes Among Women With, Without SARS-CoV-2 Infection
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, NOVEMBER 19, 2020
Media advisory: The full study is linked to this news release.
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: A large, single-institution observational study suggests SARS-CoV-2 infection during pregnancy wasn’t associated with adverse pregnancy outcomes.
Authors: Emily H. Adhikari, M.D., of the University of Texas Southwestern Medical Center in Dallas, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.29256)
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Delirium in Older Patients With COVID-19
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, NOVEMBER 19, 2020
Media advisory: The full study is linked to this news release.
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: How frequently older adults with COVID-19 present to the emergency department with delirium was examined in this observational study.
Authors: Maura Kennedy, M.D., M.P.H., of Massachusetts General Hospital and Harvard Medical School in Boston, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.29540)
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Evaluation of Tracheal Complications in Patients With COVID-19
JAMA Otolaryngology–Head & Neck Surgery
EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, NOVEMBER 19, 2020
Media advisory: The full study is linked to this news release.
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What The Study Did: Whether patients with COVID-19 had higher risk of tracheal complications after prolonged invasive mechanical ventilation and the possible reasons why were investigated in this study.
Authors: Giacomo Fiacchini, M.D., of the University of Pisa in Italy, is the corresponding author.
(doi:10.1001/jamaoto.2020.4148)
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Eye Protection for Patients With COVID-19 Undergoing Prolonged Prone-Position Ventilation
JAMA Ophthalmology
EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, NOVEMBER 19, 2020
Media advisory: The full study is linked to this news release.
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What The Study Did: Researchers report two cases of ophthalmic clinical examination findings in patients who underwent prolonged prone positioning in the intensive care unit during the COVID-19 pandemic.
Authors: Howard D. Pomeranz, M.D., Ph.D., of Northwell Health in Great Neck, New York, is the corresponding author.
(doi:10.1001/jamaophthalmol.2020.4988)
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Omega-3 Fatty Acids vs Corn Oil, Major Adverse Cardiovascular Events in Patients at High Risk
JAMA
EMBARGOED FOR RELEASE: 10 A.M. (ET), SUNDAY, NOVEMBER 15, 2020
Media advisory: The full study, editorial and editor’s note are linked to this news release. The study is being released to coincide with the American Heart Association Scientific Sessions 2020.
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What The Study Did: This randomized trial examines the effects on cardiovascular outcomes of a carboxylic acid formulation of EPA and DHA (omega-3 CA) with documented favorable effects on lipid and inflammatory markers in patients with atherogenic dyslipidemia and high cardiovascular risk.
Authors: Steven E. Nissen, M.D.,of the Cleveland Clinic Heart and Vascular Institute in Cleveland, is the corresponding author.
(doi:10.1001/jama.22258)
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Need for More and Better Testing for COVID-19
JAMA
EMBARGOED FOR RELEASE: 10 A.M. (ET), FRIDAY, NOVEMBER 13, 2020
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What The Study Did: This Viewpoint discusses the need for new and better testing for COVID-19 to help prevent community transmission, and it explains the limitations of such testing, including performance in the asymptomatic phase and access in resource-limited communities.
Authors: Yukari C. Manabe, M.D., of Johns Hopkins University in Baltimore, is the corresponding author.
(doi:10.1001/jama.21694)
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Hospital-Acquired SARS-CoV-2 Infection
JAMA
EMBARGOED FOR RELEASE: 10 A.M. (ET), FRIDAY, NOVEMBER 13, 2020
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What The Study Did: The rare incidence of nosocomial SARS-CoV-2 infection is reviewed in this Viewpoint, which also discusses ways it can be minimized, including use of surgical masks, proper ventilation, physical distancing, eye protection, regular testing and the availability of sick leave for health care workers.
Authors: Aaron Richterman, M.D., of the Hospital of the University of Pennsylvania in Philadelphia, is the corresponding author.
(doi:10.1001/jama.2020.21399)
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Changes in Outpatient Care Delivery, Telemedicine During COVID-19 Pandemic
JAMA Internal Medicine
EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, NOVEMBER 16, 2020
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What The Study Did: To understand how telemedicine compensated for declining outpatient volume and geographic variation in changing patterns of outpatient care, researchers examined telemedicine and in-person outpatient visits in 2020 among a national sample of 16.7 million people with commercial or Medicare Advantage insurance.
Author: Michael L. Barnett, M.D., M.S., of the Harvard T. H. Chan School of Public Health in Boston, is the corresponding author.
(doi:10.1001/jamainternmed.2020.5928)
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Diaphragm Pathology in Critically Ill Patients With COVID-19
JAMA Internal Medicine
EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, NOVEMBER 16, 2020
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What The Study Did: The aim of this study was to investigate the association of severe COVID-19 with the respiratory muscles in critically ill patients and compare the findings with those who had been critically ill without COVID-19.
Author: Coen Ottenheijm, Ph.D., of Amsterdam UMC in The Netherlands, is the corresponding author.
(doi:10.1001/jamainternmed.2020.6278)
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Outcomes for Out-of-Hospital Cardiac Arrest During COVID-19 Pandemic
JAMA Cardiology
EMBARGOED FOR RELEASE: 12 P.M. (ET), SATURDAY, NOVEMBER 14, 2020
Media advisory: The full study and editorial are linked to this news release. The full study is linked to this news release. The study is being released to coincide with the American Heart Association Scientific Sessions 2020.
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What The Study Did: This study used a large U.S. registry of out-of-hospital cardiac arrests to asses the association between the COVID-19 pandemic and the outcomes of out-of-hospital cardiac arrests, including in areas with low and moderate COVID-19 disease.
Authors: Paul S. Chan, M.D., M.Sc., of Saint Luke’s Mid America Heart Institute in Kansas City, Missouri, is the corresponding author.
(doi:10.1001/jamacardio.2020.6210)
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Effect of Fluvoxamine vs Placebo on Clinical Deterioration in Outpatients With Symptomatic COVID-19
JAMA
EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, NOVEMBER 12, 2020
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What The Study Did: This randomized trial compares the effects of fluvoxamine, a selective serotonin reuptake inhibitor with immunomodulatory effects, versus placebo on a composite of dyspnea or pneumonia and oxygen desaturation among adult outpatients with polymerase chain reaction-confirmed mild COVID-19 illness.
Authors: Eric J. Lenze, M.D., of the Washington University School of Medicine in St. Louis, is the corresponding author.
(doi:10.1001/jama.2020.22760)
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Assessment of SARS-CoV-2 RNA Test Results Among Patients Who Recovered From COVID-19 With Prior Negative Results
JAMA Internal Medicine
EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, NOVEMBER 12, 2020
Media advisory: The full study and editor’s note are linked to this news release.
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What The Study Did: Positive real-time polymerase chain reaction nasal-oropharyngeal swab results from patients who recovered from COVID-19 with prior negative results are examined in this study.
Authors: Brunella Posteraro, Ph.D., of the Università Cattolica del Sacro Cuore in Rome, Italy, is the corresponding author.
(doi:10.1001/jamainternmed.2020.7570)
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How Willing Are Patients to Enroll in Cancer Clinical Trials Amid COVID-19 Pandemic?
JAMA Oncology
EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, NOVEMBER 12, 2020
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What The Study Did: Researchers surveyed a large group of cancer survivors about their attitudes toward trial participation during the COVID-19 pandemic.
Authors: Mark E. Fleury, Ph.D., of the American Cancer Society Cancer Action Network in Washington, D.C., is the corresponding author.
(doi:10.1001/jamaoncol.2020.5748)
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Effect of Vitamin B12 Injection on Vocal Performance of Professional Singers
JAMA Otolaryngology–Head & Neck Surgery
EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, NOVEMBER 12, 2020
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What The Study Did: Researchers in this randomized clinical trial looked at whether a vitamin B12 injection improved mild singing-related symptoms such as reduced stamina and vocal fatigue among professional singers.
Authors: Michael M. Johns III, M.D., of the University of Southern California, Los Angeles, is the corresponding author.
(doi:10.1001/jamaoto.2020.4026)
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Years of Life Lost Associated With School Closures During COVID-19
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, NOVEMBER 12, 2020
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Potential years of life lost among U.S. primary school-age children associated with school closures during the COVID-19 pandemic are estimated in this decision analytical model.
Authors: Dimitri A. Christakis, M.D., M.P.H., of the Seattle Children’s Research Institute and editor of JAMA Pediatrics, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.28786)
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Transgender Patients With Cancer
JAMA Oncology
EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, NOVEMBER 12, 2020
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What The Study Did: This case series examined demographic, clinical and treatment characteristics of transgender patients with cancer and their outcomes
Authors: Daphne A. Haas-Kogan, M.D., and Kevin X. Liu, M.D., D.Phil., of Brigham and Women’s Hospital/Dana-Farber Cancer Institute in Boston, are the corresponding authors.
(doi:10.1001/jamaoncol.2020.5671)
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Effect of Hydroxychloroquine on Clinical Status
JAMA
EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, NOVEMBER 9, 2020
Media advisory: The full study and editorial are linked to this news release.
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What The Study Did: This randomized trial compares the effects of hydroxychloroquine versus placebo on patients’ clinical status at 14 days (home, requiring noninvasive or invasive ventilation or extracorporeal membrane oxygenation, hospitalized, died) among adults hospitalized with COVID-19.
Authors: Wesley H. Self, M.D., M.P.H., of the Vanderbilt University Medical Center in Nashville, Tennessee, is the corresponding author.
(doi:10.1001/jama.2020.22240)
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Speed, Evidence, Safety Characteristics of Vaccine Approvals by FDA
JAMA Internal Medicine
EMBARGOED FOR RELEASE: 1 P.M. (ET), TUESDAY, NOVEMBER 10, 2020
Media advisory: The full study is linked to this news release.
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What The Study Did: Amid an urgent need to develop a safe and effective vaccine to prevent COVID-19, researchers evaluated all new vaccines approved by the U.S. Food and Drug Administration over the last decade, characterizing premarket development and regulatory review times, the clinical evidence on which approval was based, and the size and follow-up duration of the prelicensure safety database.
Authors: Joseph S. Ross, M.D., M.H.S., of the Yale University School of Medicine in New Haven, Connecticut, is the corresponding author.
(doi:10.1001/jamainternmed.2020.7472)
Editor’s Note: The article includes conflict of interest disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Here’s a link to provide your readers free access to the full-text article
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Examining Association Between Highly Restrictive State Abortion Policies, Abortion Rates
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, NOVEMBER 9, 2020
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2020.24610?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=110920
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: This study looked at the association between restrictive abortion laws in 18 states and state abortion rates from 2000 to 2014.
Authors: Benjamin P. Brown, M.D., M.S., of the Alpert Medical School of Brown University in Providence, Rhode Island, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.24610)
Editor’s Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Effectiveness of E-Cigarettes Plus Counseling vs Only Counseling for Quitting Smoking
JAMA
EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, NOVEMBER 10, 2020
Media advisory: The full study and editorial are linked to this news release. A visual abstract is below.
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What The Study Did: Researchers in this randomized clinical trial compared the effect on adults trying to quit smoking of using e-cigarettes plus individual counseling versus counseling alone.
Authors: Mark J. Eisenberg, M.D., M.P.H., of Jewish General Hospital in Montréal, Canada, is the corresponding author.
Visual Abstract
(doi:10.1001/jama.2020.18889)
Editor’s Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Effect of Vitamin D, Omega-3 Supplements, Strength Training on Health of Older Adults
JAMA
EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, NOVEMBER 10, 2020
Media advisory: The full study is linked to this news release.
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What The Study Did: This randomized clinical trial investigated whether vitamin D, omega-3 fatty acid supplements and a strength-training exercise program, alone or in combination, improved health outcomes such as blood pressure and cognitive function among adults age 70 and older.
Authors: Heike A. Bischoff-Ferrari, M.D., Dr.P.H., of University Hospital Zurich in Zurich, Switzerland, is the corresponding author.
(doi:10.1001/jama.2020.16909)
Editor’s Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Changes in Birth Rates After Elimination of Cost Sharing for Contraception
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, NOVEMBER 6, 2020
Media advisory: The full study is linked to this news release.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2020.24398?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=110620
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Researchers assessed changes in birth rates by income level among commercially insured women before and after the elimination of cost sharing for contraception under the Patient Protection and Affordable Care Act.
Authors: Vanessa K. Dalton, M.D., of the University of Michigan in Ann Arbor, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.24398)
Editor’s Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Clinicians’ Experiences of Patient Care on Limited Resources During COVID-19
JAMA Network Open
EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, NOVEMBER 6, 2020
Media advisory: The full study is linked to this news release.
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Clinicians in the U.S. were interviewed and described their experiences of planning and providing care for patients in settings of limited resources during the COVID-19 pandemic.
Authors: Catherine R. Butler, M.D., M.A., of the University of Washington in Seattle, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.27315)
Editor’s Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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USPSTF Statement on Screening for High Blood Pressure in Children, Adolescents
JAMA
EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, NOVEMBER 10, 2020
Media advisory: To contact the U.S. Preventive Services Task Force, email the Media Coordinator at Newsroom@USPSTF.net or call 202-572-2044. The full report and related articles are linked to this news release.
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Bottom Line: The U.S. Preventive Services Task Force (USPSTF) concludes that the current evidence is insufficient to make a recommendation about screening for high blood pressure in children and adolescents. High blood pressure (both primary and secondary) occurs in 3 to 4 percent of children and adolescents in the United States. The USPSTF routinely makes recommendations about the effectiveness of preventive care services and this statement, which applies to children and teens ages 3 to 18 not known to have hypertension or who are without symptoms, is consistent with its 2013 statement.
(doi:10.1001/jama.2020.20122)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.
Note: More information about the U.S. Preventive Services Task Force, its process, and its recommendations can be found on the newsroom page of its website.
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