What The Study Did: The likelihood of older adults being excluded in randomized clinical trials for COVID-19 treatment and vaccine interventions is evaluated in this study.
Authors: Sharon K. Inouye, M.D., M.P.H., of Marcus Institute for Aging Research, Hebrew SeniorLife, Harvard Medical School in Boston, is the corresponding author.
(doi:10.1001/jamainternmed.2020.5084)
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About The Patient Page: How parents can help their children adjust sleep schedules, especially during the COVID-19 pandemic, is discussed in this Patient Page.
Authors: Mori Stern, M.D., Mary H.Wagner, M.D., and Lindsay A.Thompson, M.D., M.S., of the University of Florida College of Medicine in Gainesville, are the authors.
(doi:10.1001/jamapediatrics.2020.2784)
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What The Study Did: Outcomes of in-hospital cardiac arrest among patients with COVID-19 are examined in this case series.
Authors: Corey Mayer, D.O., M.B.A., of the William Beaumont Hospital in Royal Oak, Michigan, is the corresponding author.
(doi:10.1001/jamainternmed.2020.4796)
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What The Study Did: Survey data were used to examine the association between sexual orientation (exclusively heterosexual, mostly heterosexual, lesbian, gay or bisexual) and migraine.
Authors: Jason M. Nagata, M.D., M.Sc., of the University of California, San Francisco, is the corresponding author.
(doi:10.1001/jamaneurol.2020.3406)
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What The Study Did: This randomized clinical trial looked at the effect on weight loss and metabolic health of restricting eating to between 12 p.m. and 8 p.m. among overweight and obese individuals.
Authors: Ethan J. Weiss, M.D., of the University of California, San Francisco, is the corresponding author.
(doi:10.1001/jamainternmed.2020.4153)
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What The Study Did: This analysis of a randomized clinical trial compares the development of celiac disease in infants with gluten introduced into their diet before the age of 6 months compared with after.
Authors: Gideon Lack, M.B., B.Ch., of King’s College London, is the corresponding author.
(doi:10.1001/jamapediatrics.2020.2893)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: This observational study investigated whether presenting comorbidities in patients with COVID-19 in New York differed by race/ethnicity and whether case fatality rates varied among different ethnic and racial groups while accounting for presenting comorbidities and other risk factors.
Authors: Madhur K. Garg, M.D., and Andrew D. Racine, M.D., Ph.D., of the Montefiore Medical Center and Albert Einstein College of Medicine in New York, are the corresponding authors.
(doi:10.1001/jamanetworkopen.2020.19795)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Researchers investigated the association between race and COVID-19 after accounting for age, sex, socioeconomic status and comorbidities.
Authors: L. Silvia Muñoz-Price, M.D., Ph.D., of the Medical College of Wisconsin in Milwaukee, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.21892)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: This observational study examined survival rates and the use of chemotherapy before surgery among women with advanced-stage epithelial ovarian cancer in the United States from 2004 to 2016.
Authors: Alexander Melamed, M.D., M.P.H., of the NewYork-Presbyterian/Columbia University Irving Medical Center, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.17517)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did:Researchers examined changes in how common cardiovascular disease was in the highest-income earners compared with the rest of the population in the United States between 1999 and 2016.
Authors: Salma M. Abdalla, M.B.B.S., M.P.H., of the Boston University School of Public Health, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.18150)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Researchers evaluated the proportion of patients who completed COVID-19 testing and the proportion of positive cases using language as a surrogate for immigrant status.
Authors: H. Nina Kim, M.D., M.Sc., and Herbert C. Duber, M.D., M.P.H., of the University of Washington in Seattle, are the corresponding authors.
(doi:10.1001/jamanetworkopen.2020.21213)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: This observational study used data from the Department of Veterans Affairs (VA) health care system to examine what risk factors are associated with hospitalization, mechanical ventilation and death among patients with SARS-CoV-2 infection.
Authors: George N. Ioannou, B.M.B.Ch., M.S., of the Veterans Affairs Puget Sound Healthcare System and the University of Washington in Seattle, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.22310)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: The potential use of red blood cell distribution width for risk stratification of patients with COVID-19 was looked at in this observational study.
Authors: John M. Higgins, M.D., and Jonathan C. T. Carlson, M.D., Ph.D., of Massachusetts General Hospital and Harvard Medical School in Boston, are the corresponding authors.
(doi:10.1001/jamanetworkopen.2020.22058)
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What The Study Did: Researchers investigated the effectiveness of using measurements of how pupils react to light as physiologic biomarker to help diagnose sports-related concussion in adolescents.
Authors: Christina L. Master, M.D., of Children’s Hospital of Philadelphia, is the corresponding author.
(doi:10.1001/jamaophthalmol.2020.3466)
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What The Study Did: Researchers investigated whether cannabis use during pregnancy was associated with various childhood outcomes, including cognition, social problems and brain structure.
Authors: Sarah E. Paul, B.A., and Ryan Bogdan, Ph.D., of Washington University in St. Louis, are the corresponding authors.
(doi:10.1001/jamapsychiatry.2020.2902)
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What The Viewpoint Says: The amplified impact of COVID-19 on vulnerable populations has important implications for individuals at risk of or exploited in human trafficking.
Authors: Jonathan Todres, J.D., of the Georgia State University College of Law in Atlanta, is the corresponding author.
(doi:10.1001/jamapediatrics.2020.3595)
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What The Editorial Says: Authors of this editorial review the evidence for the management of patients with the acute respiratory distress syndrome (ARDS) that may apply to patients with severe COVID-19, what has been learned about treatment of these patients, and the gaps in knowledge that remain.
Authors: Carolyn S. Calfee, M.D., M.A.S., of the University of California, San Francisco, is the corresponding author.
(doi:10.1001/jamainternmed.2020.6047)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Changes over nearly two decades in the rate of hospitalizations and in-hospital deaths from alcohol use disorder in the U.S. were examined in this study.
Authors: Jasvinder A. Singh, M.B.B.S., M.P.H., of the University of Alabama at Birmingham, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.16580)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Researchers in this observational study investigated the association between the amount of sleep at night and cognitive decline among participants in two large studies on aging.
Authors: Wuxiang Xie, Ph.D., of Peking University First Hospital in Beijing, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.13573)
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What The Study Did: This randomized clinical trial compared the effectiveness of two smartphone apps that use different approaches to help smokers quit.
Authors: Jonathan B. Bricker, Ph.D., of the Fred Hutchinson Cancer Research Center in Seattle, is the corresponding author.
(doi:10.1001/jamainternmed.2020.4055)
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What The Study Did: Researchers in this observational study examined the association between wearing eyeglasses daily and susceptibility to COVID-19.
Authors: Yiping Wei, M.D., Ph.D., and Jianjun Xu, M.D., Ph.D., of the Second Affiliated Hospital of Nanchang University in Nanchang, China, are the corresponding authors.
(doi:10.1001/jamaophthalmol.2020.3906)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Researchers examined changes in the proportion of female corresponding authors in bioRxiv (biorxiv.org) and medRxiv (medrxiv.org), which are online archive and distribution services for unpublished preprint research in the life and health sciences, respectively, before and during the COVID-19 pandemic.
Authors: Mackenzie R. Wehner, M.D, MPhil., of the University of Texas MD Anderson Cancer Center in Houston, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.20335)
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What The Study Did: This laboratory study assessed the efficacy of the nasal antiseptic solution povidone-iodine against transmission of SARS-C0V-2.
Authors: Samantha Frank, M.D., of the University of Connecticut School of Medicine in Farmington, is the corresponding author.
(doi:10.1001/jamaoto.2020.3053)
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What The Study Did: Changes in lung cancer treatment during the COVID-19 pandemic were evaluated in this study.
Authors: Nathaniel Bouganim, M.D., of Cedars Cancer Center, McGill University Health Centre in Montreal, is the corresponding author.
(doi:10.1001/jamaoncol.2020.4408)
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What The Study Did: Researchers in this observational study investigated the association between the number of cups of coffee consumed per day and survival in patients with advanced or metastatic colorectal cancer.
Authors: Christopher Mackintosh, M.L.A., a medical student at the Mayo Clinic School of Medicine in Rochester, Minnesota, is the corresponding author.
(doi:10.1001/jamaoncol.2020.3938)
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What The Study Did: Researchers investigated differences in quality of life and other outcomes (including physical functioning, body image, sexual health, anxiety and depressive symptoms) by type of breast cancer surgery (such as mastectomy or breast conserving surgery) in women 40 and younger.
Authors: Shoshana M. Rosenberg, Sc.D., M.P.H., of the Dana-Farber Cancer Institute in Boston, is the corresponding author.
(doi:10.1001/jamasurg.2020.3325)
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What The Study Did: This observational study looked at whether adverse pregnancy outcomes such as preterm delivery, gestational diabetes and low birth weight are associated with an increased risk of atherosclerotic cardiovascular disease in postmenopausal women, independent of traditional risk factors.
Authors: Nisha I. Parikh, M.D., M.P.H., of the University of California, San Francisco, is the corresponding author.
(doi:10.1001/jamacardio.2020.4097)
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What The Study Did: This case-control study compares the rates of test results indicating SARS-CoV-2 infection among children and adults admitted to a single hospital in Milan, Italy, for noninfectious reasons and without COVID-19 symptoms.
Authors: Carlo Agostoni, M.D., of Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico in Milan, Italy, is the corresponding author.
(doi:10.1001/jamapediatrics.2020.3595)
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What The Article Says: This Viewpoint examines the evidence for vaccination of children against COVID-19.
Authors: Lainie Friedman Ross, M.D., Ph.D., of the University of Chicago, is the corresponding author.
(doi:10.1001/jamapediatrics.2020.3019)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Psychological symptoms, nonsuicidal self-injury and suicidal ideation, plans, and attempts among children and adolescents were investigated in this observational study before the COVID-19 outbreak started (early November 2019) and two weeks after school reopening (mid-May 2020) in an area of China with low risk of COVID-19.
Authors: Ying Sun, M.D., of Anhui Medical University in the Anhui province of China, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.21482)
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What The Study Did: This study investigated the use of cardiac magnetic resonance imaging in competitive college athletes who recovered from COVID-19 to detect myocardial inflammation that would identify high-risk athletes for return to competitive play.
Authors: Saurabh Rajpal, M.B.B.S., M.D., of Division of Ohio State University in Columbus, is the corresponding author.
(doi:10.1001/jamacardio.2020.4916)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Researchers compared changes from 2000 to 2017 in premature deaths in the U.S. due to drug poisonings, suicide and alcohol-induced causes by geographic areas and demographic characteristics.
Authors: Meredith S. Shiels, Ph.D., of the National Cancer Institute in Rockville, Maryland, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.16217)
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What The Article Says: This Viewpoint discusses the disproportionate burdens related to COVID-19 experienced by minority populations as well as strategies to limit disparities in health care, access and outcomes.
Authors: Regan W. Bergmark, M.D., of Harvard Medical School and Brigham and Women’s Hospital in Boston, is the corresponding author.
(doi:10.1001/jamaoto.2020.2874)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: This observational study investigated demographic and military service characteristics associated with suicide risk among U.S. veterans after the transition from active military service to civilian life.
Authors: Mark A. Reger, Ph.D., of the Veterans Affairs Puget Sound Health Care System in Seattle, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.16261)
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What The Study Did: The clinical profile and outcomes of 3,222 young adults (ages 18 to 34 years) who required hospitalization for COVID-19 in the U.S. are examined in this case series.
Authors: Scott D. Solomon, M.D., of Brigham and Women’s Hospital in Boston, is the corresponding author.
(doi:10.1001/jamainternmed.2020.5313)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Over the first 12 weeks of the COVID-19 pandemic, about 700 patients were admitted to Brigham and Women’s Hospital in Boston with COVID-19 and more than 8,000 patients without COVID-19. Researchers in this study reviewed all patients diagnosed with COVID-19 on hospital day three or later or within 14 days of hospital discharge to quantify the incidence of nosocomial transmission and to assess the effectiveness of the infection control program at the hospital.
Authors: Chanu Rhee, M.D., M.P.H., of Harvard Medical School and Harvard Pilgrim Health Care Institute in Boston, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.20498)
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EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, SEPTEMBER 9, 2020
Media advisory: The full study and related articles are linked to this news release. A live stream is planned for 12:30 P.M. Thursday, September 10, at this link: http://ja.ma/covidtrends
What The Study Did: National survey data were used to examine how blood pressure control changed overall among U.S. adults with high blood pressure between 1999-2000 and 2017-2018 and by age, race, insurance type and access to health care.
Authors: Paul Muntner, Ph.D., of the University of Alabama at Birmingham, is the corresponding author.
(doi:10.1001/jama.2020.14545)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: The risk of future dementia associated with overall alcohol consumption and alcohol-induced loss of consciousness in a population of current drinkers was examined in this observational study with more than 131,000 adults.
Authors: Mika Kivimaki, Ph.D., of University College London in London, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.16084)
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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Anonymous mobile phone location data were used to examine travel and home dwelling time patterns before and after enactment of stay-at-home orders in U.S. states to examine associations between changes in mobility and the COVID-19 curve.
Authors: Song Gao, Ph.D., and Jonathan A. Patz, M.D., of the University of Wisconsin in Madison, are the corresponding authors.
(doi:10.1001/jamanetworkopen.2020.20485)
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What The Study Did: This study combined the results of 21 studies to estimate the proportion of Black children, adolescents and adults with attention-deficit/hyperactivity disorder (ADHD) and identify the associated risk factors.
Authors: Jude Mary Cénat, Ph.D., of the University of Ottawa in Ottawa, Canada, is the corresponding author.
(doi:10.1001/jamapsychiatry.2020.2788)
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: Clinical features of COVID-19 are compared in this observational study with those of influenza A and B in U.S. children.
Authors: Xiaoyan Song, Ph.D, M.B.B.S., of the Children’s National Hospital in Washington, D.C., is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.20495)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
What The Study Did: This study examined the location of mass shootings (four or more people injured or killed by a firearm) last year relative to schools and other places frequented by children.
Authors: Michael L. Nance, M.D., of Children’s Hospital of Philadelphia, is the corresponding author.
(doi:10.1001/jamapediatrics.2020.3371)
Editor’s Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
What The Article Says: A hospitalist charts his emotional journey in this narrative essay from when once brightly colored signs declared hospital workers as heroes to now when the signs have faded and the steady and intense work of helping patients with COVID-19 has seemingly become mundane.
Authors: Bernard E. Trappey, M.D., of the University of Minnesota in Minneapolis, is the author.
(doi:10.1001/jama.2020.17249)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
What The Study Did: Researchers investigated data collection and sharing practices of mobile apps played by preschool-age children and the associated sociodemographic characteristics of the children.
Authors: Jenny S. Radesky, M.D., of the University of Michigan Medical School in Ann Arbor, is the corresponding author.
(doi:10.1001/jamapediatrics.2020.3345)
Editor’s Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
What The Study Did: Survey data were used to assess changes in the use of electronic cigarettes among U.S. adults from 2016 to 2018.
Authors: Michael J. Blaha, M.D., M.P.H., of the Johns Hopkins Ciccarone Center for the Prevention of Cardiovascular Disease in Baltimore, is the corresponding author.
(doi:10.1001/jamainternmed.2020.2817)
Editor’s Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
What The Study Did: This observational study examines whether patients’ most recent vitamin D levels and treatment for insufficient vitamin D levels are associated with test results for COVID-19.
Authors: David O. Meltzer M.D., Ph.D., of the University of Chicago, is the corresponding author.
(doi:10.1001/jamanetworkopen.2020.19722)
Editor’s Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
What The Article Says: This Viewpoint discusses how the COVID-19 pandemic may reshape clinical practice and clinical research as new technologies are incorporated and old practices are revisited and revamped.
Authors: Lillian L. Siu, M.D., of the Princess Margaret Cancer Centre in Toronto, Canada, is the corresponding author.
(doi:10.1001/jamaoncol.2020.4240)
Editor’s Note: The article includes conflict of interest disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
What The Article Says: This essay highlights the lessons to be learned from the COVID-19 pandemic on the importance of recognizing communication difficulties among those with hearing impairment.
Authors: Maura K. Cosetti, M.D., of the New York Eye and Ear Infirmary of Mount Sinai in New York, is the author.
(doi:10.1001/jamaoto.2020.2532)
Editor’s Note: The article includes conflict of interest disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflicts of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
What The Article Says: The timing of performing tracheostomies, which are aerosol-generating procedures that may cause increased risk of COVID-19 transmission to health care workers, is examined in this Viewpoint..
Authors: Michael J. Brenner, M.D., of the University of Michigan Medical School in Ann Arbor, is the corresponding author.
(doi:10.1001/jamaoto.2020.2630)
Editor’s Note: The article includes conflict of interest disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflicts of interest and financial disclosures, and funding and support.
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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or emailmedia relations.
