Postural Orthostatic Tachycardia Syndrome (POTS)
JAMA 10.1001/jama.2026.14809August 24, 2026 at 11:00 AM EDT
POTS is a chronic autonomic disorder associated with functional impairment and reduced quality of life that is diagnosed based on characteristic orthostatic symptoms in the absence of orthostatic hypotension after excluding alternative causes of sinus tachycardia. Treatment involves nonpharmacological measures (such as increased fluid and sodium intake), lower-body compression garments, structured exercise training, and individualized pharmacological therapy.
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