Prevalence of Cardiovascular-Kidney-Metabolic Syndrome Stages in US Adults

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, MAY 8, 2024

Media advisory: The full study is linked to this news release.

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About The Study: Almost 90% of U.S. adults met criteria for cardiovascular, kidney, and metabolic (CKM) syndrome (stage 1 or higher) and 15% met criteria for advanced stages, neither of which improved between 2011 and 2020. Substantial between-subgroup differences in advanced stages were observed, with older age, men, and Black adults at increased risk. Cardiovascular, kidney, and metabolic diseases are pathophysiologically interrelated and were the leading causes of death in 2021. In 2023, the American Heart Association introduced a novel staging construct, termed CKM syndrome, to enhance multidisciplinary approaches to prevention, risk stratification, and management of these disorders.

Corresponding Author: To contact the corresponding author, Muthiah Vaduganathan, M.D., M.P.H., email mvaduganathan@bwh.harvard.edu.

 

(doi:10.1001/jama.2024.6892)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Multilevel Characteristics of Cumulative Symptom Burden in Young Survivors of Childhood Cancer

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, MAY 7, 2024

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: The findings of this study suggest that symptoms are prevalent years after young childhood cancer survivors’ initial cancer diagnosis, and interventions to reduce caregiver anxiety and neighborhood adversity and improve resilience may alleviate symptom burden. 

Corresponding Author: To contact the corresponding author, I-Chan Huang, Ph.D., email i-chan.huang@stjude.org.

  

(doi:10.1001/jamanetworkopen.2024.10145)

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Social Determinants of Health and the Availability of Cancer Clinical Trials in the US

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, MAY 7, 2024

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: Substantial geographic disparities in cancer clinical trials availability exist throughout the United States, with the most socially vulnerable counties being far less likely to have any trial and having only a fraction of trials available, a disparity that has worsened over time. 

Corresponding Author: To contact the corresponding author, Rishi Robert Sekar, M.D., M.S., email rsekar@med.umich.edu. 

 

(doi:10.1001/jamanetworkopen.2024.10162)

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Cytisinicline for Vaping Cessation in Adults Using Nicotine E-Cigarettes

Posted by Jim Michalski

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Behavioral Interventions to Improve Breast Cancer Screening Outreach

Posted by Jim Michalski

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, MAY 6, 2024

Media advisory: The full study is linked to this news release.

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About The Study: These findings show that text messaging women after initial breast cancer screening outreach via either electronic portal or mailings, as well as bulk ordering with or without text messaging, can increase mammogram completion rates.  

Corresponding Author: To contact the corresponding author Shivan J. Mehta, M.D., M.B.A., M.S.H.P., email shivan.mehta@pennmedicine.upenn.edu.

 

(doi:10.1001/jamainternmed.2024.0507)

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Racial and Ethnic Disparities in Initiation of Direct Oral Anticoagulants Among Medicare Beneficiaries

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, MAY 6, 2024

Media advisory: The full study and editorial are linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this cohort study of Medicare patients with atrial fibrillation, Black and Hispanic patients were less likely to initiate direct oral anticoagulants for atrial fibrillation, although these differences diminished over time. Identifying the factors behind these early disparities is crucial for ensuring equitable access to novel therapies as they emerge for Black and Hispanic populations. 

Corresponding Authors: To contact the corresponding authors, email Kamika R. Reynolds, M.S., Ph.D. (kreynolds@ifh.rutgers.edu) and Chintan V. Dave, Pharm.D., Ph.D. (cdave@ifh.rutgers.edu). 

 

(doi:10.1001/jamanetworkopen.2024.9465)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Racial and Ethnic Disparities in All-Cause and Cause-Specific Mortality Among US Youth

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 3:30 P.M. (ET), SATURDAY, MAY 4, 2024

Media advisory: The full study and editorial are linked to this news release. This study is being released to coincide with presentation at the Pediatric Academic Societies meeting.

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About The Study: Racial and ethnic disparities were observed for almost all leading causes of injury and disease that were associated with recent increases in youth mortality rates. Addressing the increasing disparities affecting American Indian or Alaska Native and Black youth will require efforts to prevent homicide and suicide, especially those events involving firearms. 

Authors: Elizabeth R. Wolf, M.D., M.P.H., of the Virginia Commonwealth University School of Medicine in Richmond, is the corresponding author.

 

(doi:10.1001/jama.2024.3908)

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Loss of Medicaid Coverage During the Renewal Process

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama-health-forum/fullarticle/10.1001/jamahealthforum.2024.0839?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=050324

About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

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Associations of Internal Medicine Residency Milestone Ratings and Certification Examination Scores With Patient Outcomes

Posted by Jim Michalski

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Long-Term Cardiovascular Outcomes in Children and Adolescents With Hypertension

Posted by Jim Michalski

JAMA Pediatrics

EMBARGOED FOR RELEASE: 9 A.M. (ET), MONDAY, MAY 6, 2024

Media advisory: The full study is linked to this news release. This study is being released to coincide with presentation at the Pediatric Academic Societies meeting.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapediatrics/fullarticle/10.1001/jamapediatrics.2024.1543?guestAccessKey=629b52f1-cf25-4fcb-86b2-cd4d43237377&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=050624

 

About The Study: Children diagnosed with hypertension had a higher associated long-term risk of major adverse cardiac events compared with controls without hypertension. Improved detection, follow-up, and control of pediatric hypertension may reduce the risk of adult cardiovascular disease. 

Authors: Rahul Chanchlani, M.B.B.S., M.D., M.Sc., of McMaster University in Hamilton, Canada, is the corresponding author.

 

(doi:10.1001/jamapediatrics.2024.1543)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Early Neurodevelopmental Assessments for Predicting Long-Term Outcomes in Infants at High Risk of Cerebral Palsy

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 1 P.M. (ET), MONDAY, MAY 6, 2024

Media advisory: The full study is linked to this news release. This study is being released to coincide with presentation at the Pediatric Academic Societies meeting.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: The results of this study support the potential to identify cerebral palsy and its severity as early as corrected age 3 to 4 months through early neurodevelopmental assessments, but the role of these tests is limited in identifying cognitive and neurodevelopmental impairments. 

Authors: Abdul Razak, M.D., of Monash University in Melbourne, Australia, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2024.9053)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Outcomes of Children Admitted to a Pediatric Observation Unit With a Psychiatric Comanagement Model

Posted by Jim Michalski

JAMA Pediatrics

EMBARGOED FOR RELEASE: 7 A.M. (ET), SUNDAY, MAY 5, 2024

Media advisory: The full study is linked to this news release. This study is being released to coincide with presentation at the Pediatric Academic Societies meeting.

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About The Study: The findings of this study show a significantly lower pediatric emergency department length of stay and inpatient psychiatric admission rate following pediatric observation unit care and potential savings in inpatient psychiatric resources without contributing to 30-day readmission rates. 

Authors: Rachel G. Kasdin, M.S., of the Icahn School of Medicine at Mount Sinai in New York, is the corresponding author.

 

(doi:10.1001/jamapediatrics.2024.1123)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Photokeratitis in Outdoor Event Participants Exposed to UV Radiation Display

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaophthalmology/fullarticle/10.1001/jamaophthalmol.2024.1092?guestAccessKey=04059fd0-801f-4710-bb70-6444e3135a22&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=050224

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Longer Interval Between First Colonoscopy With Negative Findings for Colorectal Cancer and Repeat Colonoscopy

Posted by Jim Michalski

JAMA Oncology

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, MAY 2, 2024

Media advisory: The full study and editorial are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaoncology/fullarticle/10.1001/jamaoncol.2024.0827?guestAccessKey=9633a19d-fa15-4a71-b4c7-a2e8d189af39&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=050224

 

About The Study: This cohort study found that for the population without a family history of colorectal cancer (CRC), the 10-year interval between colonoscopy screenings for individuals with a first colonoscopy with findings negative for CRC could potentially be extended to 15 years. A longer interval between colonoscopy screenings could be beneficial in avoiding unnecessary invasive examinations. 

Authors: Mahdi Fallah, M.D., Ph.D., of the German Cancer Research Center in Heidelberg, is the corresponding author. 

 

(doi:10.1001/jamaoncol.2024.0827)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Smoking Cessation After Initial Treatment Failure With Varenicline or Nicotine Replacement

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, MAY 2, 2024

Media advisory: The full study is linked to this news release.

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About The Study: For individuals who smoked but did not achieve abstinence after treatment with varenicline, increasing the dosage enhanced abstinence versus continuing, whereas for nonabstainers initially treated with combined nicotine replacement therapy, a dosage increase or switch to varenicline enhanced abstinence and may be viable rescue strategies. 

Authors: Paul M. Cinciripini, Ph.D., of the University of Texas MD Anderson Cancer Center in Houston, is the corresponding author.

 

(doi:10.1001/jama.2024.4183)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Deep Learning–Based Assessment of Built Environment From Satellite Images and Cardiometabolic Disease Prevalence

Posted by Jim Michalski

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https://jamanetwork.com/journals/jamacardiology/fullarticle/10.1001/jamacardio.2024.0749?guestAccessKey=ba082ea0-36e1-47b5-bde8-e290f10e494b&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=050124

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Prospective and Retrospective Measures of Child Maltreatment and Their Association With Psychopathology

Posted by Jim Michalski

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Differences in Cardiovascular Health at the Intersection of Race, Ethnicity, and Sexual Identity

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, MAY 1, 2024

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: This cross-sectional study uses National Health and Nutrition Examination Survey data to examine differences in cardiovascular health metrics at the intersection of race, ethnicity, and sexual identity. 

Authors: Nicole Rosendale, M.D., of the University of California San Francisco, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2024.9053)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Plant-Based Diets and Disease Progression in Men With Prostate Cancer

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, MAY 1, 2024

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: Higher intake of plant foods after prostate cancer diagnosis was associated with lower risk of cancer progression, this study suggests. 

Authors: Stacey A. Kenfield, Sc.D., of the University of California, San Francisco, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2024.9053)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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The Women’s Health Initiative Randomized Trials and Clinical Practice

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, MAY 1, 2024

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.6542?guestAccessKey=c8b14176-94bd-49a9-9fa2-7ec06f3cafc1&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=050124

 

About The Study: For postmenopausal women, the Women’s Health Initiative (WHI) randomized clinical trials do not support menopausal hormone therapy to prevent cardiovascular disease or other chronic diseases. Menopausal hormone therapy is appropriate to treat bothersome vasomotor symptoms among women in early menopause, without contraindications, who are interested in taking hormone therapy. The WHI evidence does not support routine supplementation with calcium plus vitamin D for menopausal women to prevent fractures or a low-fat diet with increased fruits, vegetables, and grains to prevent breast or colorectal cancer. A potential role of a low-fat dietary pattern in reducing breast cancer mortality, a secondary outcome, warrants further study. 

Authors: JoAnn E. Manson, M.D., Dr.P.H., of Brigham and Women’s Hospital, Harvard Medical School in Boston, is the corresponding author.

 

(doi:10.1001/jama.2024.6542)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Race and Ethnicity of Reproductive-Age Females Affected by State Abortion Bans

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, MAY 1, 2024

Media advisory: The full study is linked to this news release.

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About The Study: The proportions of American Indian or Alaska Native, Black, and white females of reproductive age in states with effective abortion bans were higher than in states without such policies, while proportions for other racial and ethnic groups were lower. Although these restrictive laws were not based on race, they were concentrated in states with higher proportions of American Indian or Alaska Native and Black individuals, resulting in a differential effect of restrictive abortion laws in these groups. American Indian or Alaska Native and Black populations are disproportionately affected by disparities in pregnancy-related deaths, reproductive health, and poverty. Policies improving access to the full spectrum of reproductive health care, including safe abortion, may reduce such disparities. 

Authors: Demetri Goutos, M.B.A., of the Boston University School of Public Health in Boston, is the corresponding author.

 

(doi:10.1001/jama.2024.6023)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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National Breast, Cervical, and Colorectal Cancer Screening Use in Federally Qualified Health Centers

Posted by Jim Michalski

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Physical Fitness and Risk of Mental Disorders in Children and Adolescents

Posted by Jim Michalski

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Identification of Human-Generated vs AI-Generated Research Abstracts by Health Care Professionals

Posted by Jim Michalski

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USPSTF Recommendation Statement on Screening for Breast Cancer

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, APRIL 30, 2024

Media advisory: To contact the U.S. Preventive Services Task Force, email the Media Coordinator at Newsroom@USPSTF.net or call 301-951-9203. The full report and related articles are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time and all USPSTF articles remain free indefinitely https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.5534?guestAccessKey=24c51c29-76d3-4743-9dd2-a7b14f990871&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=043024

 

Bottom Line: The U.S. Preventive Services Task Force (USPSTF) recommends biennial screening mammography for women ages 40 to 74. The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of screening mammography in women 75 years or older. The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of supplemental screening for breast cancer using breast ultrasonography or magnetic resonance imaging (MRI) in women identified to have dense breasts on an otherwise negative screening mammogram. Among all U.S. women, breast cancer is the second most common cancer and the second most common cause of cancer death. The USPSTF routinely makes recommendations about the effectiveness of preventive care services and this recommendation updates the 2016 recommendation on breast cancer screening.

 

(doi:10.1001/jama.2024.5534)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.

Note: More information about the U.S. Preventive Services Task Force, its process, and its recommendations can be found on the newsroom page of its website.

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Association of New-Onset Seizures With SARS-CoV-2 Vaccines

Posted by Jim Michalski

JAMA Neurology

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, APRIL 29, 2024

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaneurology/fullarticle/10.1001/jamaneurol.2024.0967?guestAccessKey=b4540abc-cbb6-4e8c-844d-cd259ab45960&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042924

 

About The Study: This systematic review and meta-analysis showed that the incidence proportion of new-onset seizures after SARS-CoV-2 vaccination was not statistically different between vaccine recipients and placebo recipients or unvaccinated participants in the pooled analyses of more than 118,000 participants in randomized clinical trials.

Authors: Churl-Su Kwon, M.D., M.P.H., of Columbia University in New York, is the corresponding author.

 

(doi:10.1001/jamaneurol.2024.0967)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Global Production of Active Pharmaceutical Ingredients for US Generic Drugs Experiencing Shortages

Posted by Jim Michalski

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Screening Strategies to Reduce COVID-19 Mortality in Nursing Homes

Posted by Jim Michalski

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About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

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Cardiovascular Risk Associated With Social Determinants of Health at Individual and Area Levels

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, APRIL 26, 2024

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: The findings of this study of 26,000 participants from four large U.S. studies suggest that both individual- and area-level social determinants of health may be considered in future development of atherosclerotic cardiovascular disease risk assessment tools, particularly among Black individuals. 

Authors: Yiyi Zhang, Ph.D., of Columbia University Medical Center in New York, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2024.8584)

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Aspirin vs Placebo as Adjuvant Therapy for Breast Cancer

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, APRIL 29, 2024

Media advisory: The full study and editorial are linked to this news release.

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About The Study: In this randomized, placebo-controlled clinical trial that included 3,020 patients with high-risk nonmetastatic breast cancer, daily aspirin therapy did not improve risk of breast cancer recurrence or survival in early follow-up. Despite its promise and wide availability, aspirin should not be recommended as an adjuvant breast cancer treatment. 

Authors: Wendy Y. Chen, M.D., of the Dana Farber Cancer Institute in Boston, is the corresponding author.

 

(doi:10.1001/jama.2024.4840)

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Home-Monitoring Vision Tests to Detect Active Neovascular Age-Related Macular Degeneration

Posted by Jim Michalski

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COVID-19 Vaccine–Associated Uveitis in Patients With a History of Uveitis

Posted by Jim Michalski

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Neighborhood-Level Disadvantage and Delayed Adjuvant Therapy in Head and Neck Cancer

Posted by Jim Michalski

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Disparities in Mortality by Sexual Orientation in a Large, Prospective Cohort of Female Nurses

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, APRIL 25, 2024

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.4459?guestAccessKey=5d21d2ac-e39b-415c-9fc7-ac4fb875546f&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042524

 

About The Study: In an otherwise largely homogeneous sample of female nurses, participants identifying as lesbian or bisexual had markedly earlier mortality during the study period compared with heterosexual women. These differences in mortality timing highlight the urgency of addressing modifiable risks and upstream social forces that propagate and perpetuate disparities. 

Authors: Sarah McKetta, M.D., Ph.D., of Harvard University in Boston, is the corresponding author.

 

(doi:10.1001/jama.2024.4459)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Psychiatric Symptoms, Treatment Uptake, and Barriers to Mental Health Care Among US Adults With Post–COVID-19 Condition

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, APRIL 25, 2024

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.8481?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=042524

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this nationally representative cross-sectional study of 25,000 participants, those experiencing post–COVID-19 condition (PCC) were approximately twice as likely to report depression and anxiety symptoms than other U.S. adults. Among individuals with these symptoms, adults with PCC were just as likely to have received mental health treatment but more likely to report cost-related barriers to accessing therapy. Care pathways for PCC should consider prioritizing mental health screening and affordable treatment. 

Authors: Hiten Naik, M.D., of the University of British Columbia in Vancouver, British Columbia, is the corresponding author.

 

(doi:10.1001/jamanetworkopen.2024.8481)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Stigmatization and Mental Health Impact of Chronic Pediatric Skin Disorders

Posted by Jim Michalski

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Adolescents Who Do Not Endorse Risk via the Patient Health Questionnaire Before Self-Harm or Suicide

Posted by Jim Michalski

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Cognitive Behavior Therapy vs Mindfulness in Treatment of Prolonged Grief Disorder

Posted by Jim Michalski

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Safety of Ancestral Monovalent COVID-19 Vaccines in Children

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, APRIL 24, 2024

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this cohort study of pediatric enrollees across three commercial health insurance databases, statistical signals detected for myocarditis or pericarditis after BNT162b2 (ages 12-17 years) were consistent with previous reports, and seizures after BNT162b2 (ages 2-4 years) and mRNA-1273 vaccinations (ages 2-5 years) should be further investigated in a robust epidemiologic study with confounding adjustment. The Food and Drug Administration concludes that the known and potential benefits of COVID-19 vaccination outweigh the known and potential risks of COVID-19 infection. 

Authors: Patricia C. Lloyd, Ph.D., Sc.M., of the Food and Drug Administration in Silver Spring, Maryland, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2024.8192)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Reversals in the Decline of Heart Failure Mortality in the US

Posted by Jim Michalski

JAMA Cardiology

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, APRIL 24, 2024

Media advisory: The full study is linked to this news release. 

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamacardiology/fullarticle/10.1001/jamacardio.2024.0615?guestAccessKey=5cc02b14-80a8-42e8-b507-d7a5688db4ac&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042424

 

About The Study: This analysis shows that declines in heart failure-related mortality from 1999 to 2012 have been entirely undone by reversals from 2012 to 2021, meaning that contemporary heart failure mortality rates are higher than in 1999. The origins of these reversals preceded the COVID-19 pandemic, although the larger increases in 2020 to 2021 indicate that the pandemic may have accelerated them due to limitations to health care access and possible cardiac involvement. 

Authors: Marat Fudim, M.D., M.H.S., of Duke University in Durham, North Carolina, is the corresponding author.

 

(doi:10.1001/jamacardio.2024.0615)

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Recreational Marijuana Laws and Teen Marijuana Use, 1993-2021

Posted by Jim Michalski

JAMA Psychiatry

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, APRIL 24, 2024

Media advisory: The full study is linked to this news release.

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About The Study: In this repeated cross-sectional study, there was no evidence that recreational marijuana laws were associated with encouraging youth marijuana use, based on both the logistic regression and interaction-weighted models. 

Authors: D. Mark Anderson, Ph.D., of Montana State University in Bozeman, is the corresponding author.

 

(10.1001/jamapsychiatry.2024.0698)

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Characteristics of X (Formerly Twitter) Community Notes Addressing COVID-19 Vaccine Misinformation

Posted by Jim Michalski

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Neurodevelopmental Outcomes After Late Preterm Antenatal Corticosteroids

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), WEDNESDAY, APRIL 24, 2024

Media advisory: The full study and editorial are linked to this news release.

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About The Study: In this follow-up study of a randomized clinical trial, administration of antenatal corticosteroids to persons at risk of late preterm delivery, originally shown to improve short-term neonatal respiratory outcomes but with an increased rate of hypoglycemia, was not associated with adverse childhood neurodevelopmental outcomes at age 6 or older. 

Authors: Cynthia Gyamfi-Bannerman, M.D., M.S., of the University of California, San Diego, is the corresponding author.

 

(doi:10.1001/jama.2024.4303)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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COVID-19 Vaccination and Incidence of Pediatric SARS-CoV-2 Infection and Hospitalization

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, APRIL 23, 2024

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.7822?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=042324

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: The findings of this study including 3.9 million children suggest that vaccination against SARS-CoV-2 was associated with significant reductions in COVID-19 incidence and hospitalizations among children in California. 

Authors: Justin V. Remais, Ph.D., of the University of California, Berkeley, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2024.7822)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Long-Term Taste and Smell Outcomes After COVID-19

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), TUESDAY, APRIL 23, 2024

Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: Taste dysfunction as measured objectively was absent one year after exposure to COVID-19 while some smell loss remained in nearly one-third of individuals with this exposure, likely explaining taste complaints of many individuals with post–COVID-19 condition in this study of 340 individuals with and 434 individuals without prior COVID-19. Infection with earlier untyped and Alpha variants was associated with the greatest degree of smell loss. 

Authors: Shima T. Moein, M.D., Ph.D., of the University of Pennsylvania in Philadelphia, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2024.7818)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Antihypertensive Medication and Fracture Risk in Older VHA Nursing Home Residents

Posted by Jim Michalski

JAMA Internal Medicine

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, APRIL 22, 2024

Media advisory: The full study and commentary are linked to this news release.

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About The Study: The findings of this study indicated that initiation of antihypertensive medication was associated with elevated risks of fractures and falls among older long-term care nursing home residents in the Veterans Health Administration. These risks were numerically higher among residents with dementia, higher baseline blood pressures values, and no recent antihypertensive medication use. Caution and additional monitoring are advised when initiating antihypertensive medication in this vulnerable population. 

Authors: Chintan V. Dave, Pharm.D., Ph.D., of Rutgers University in New Brunswick, New Jersey, is the corresponding author.

 

(doi:10.1001/jamainternmed.2024.0507)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Developmental Milestone Attainment in Children Before and During the Pandemic

Posted by Jim Michalski

JAMA Pediatrics

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, APRIL 22, 2024

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapediatrics/fullarticle/10.1001/jamapediatrics.2024.0683?guestAccessKey=6a03f5b4-4727-4397-b8a4-cc2fcd7629ea&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042224

 

About The Study: Modest decreases in developmental screening scores suggest reason for cautious optimism about the development of a generation of U.S. children exposed to the COVID-19 pandemic in this study including 50,000 children. Continued attention to developmental surveillance is critical since the long-term population- and individual-level implications of these changes are unclear. 

Authors: Sara B. Johnson, Ph.D., M.P.H., of the Johns Hopkins School of Medicine in Baltimore, is the corresponding author.

 

(doi:10.1001/jamapediatrics.2024.0683)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Untreated Psychiatric and Substance Use Disorders Among Caregivers With Children Reported to Child Protective Services

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama-health-forum/fullarticle/10.1001/jamahealthforum.2024.0637?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=041924

About JAMA Health Forum: JAMA Health Forum is an international, peer-reviewed, online, open access journal that addresses health policy and strategies affecting medicine, health and health care. The journal publishes original research, evidence-based reports and opinion about national and global health policy; innovative approaches to health care delivery; and health care economics, access, quality, safety, equity and reform. Its distribution will be solely digital and all content will be freely available for anyone to read.

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Preoperative GLP-1 Receptor Agonist Use and Risk of Postoperative Respiratory Complications

Posted by Jim Michalski

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, APRIL 22, 2024

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.5003?guestAccessKey=0234613c-2e74-444c-ac25-4f9e82f9b24b&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042224

 

About The Study: Preoperative use of glucagon-like peptide 1 receptor agonists (GLP-1 RAs) in patients undergoing emergency surgery was not associated with a higher risk of postoperative respiratory complications compared with patients not using GLP-1 RAs. The results of this study suggest that liberalizing withholding guidelines for GLP-1 RAs preoperatively should be considered. 

Authors: Anjali A. Dixit, M.D., M.P.H., of the Stanford University School of Medicine in Stanford, California, is the corresponding author.

 

(doi:10.1001/jama.2024.5003)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

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Self-Administered Acupressure for Probable Knee Osteoarthritis in Middle-Aged and Older Adults

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, APRIL 19, 2024

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.5830?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=041924

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: In this randomized clinical trial with 314 participants, self-administered acupressure with a brief knee health education program was efficacious and cost-effective in relieving knee pain and improving mobility in middle-aged and older adults with probable knee osteoarthritis. 

Authors: Wing-Fai Yeung, Ph.D., of the Hong Kong Polytechnic University in Hong Kong, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2024.5830)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

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Postpartum Breast Cancer and Survival in Women With Germline BRCA Pathogenic Variants

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), FRIDAY, APRIL 19, 2024

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.7421?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=041924

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: This study including 903 women with BRCA germline pathogenic variants found that a breast cancer diagnosis less than 10 years postpartum was associated with higher risk of mortality compared with nulliparous women and women diagnosed at least 10 years postpartum. These results should inform genetic counseling, prevention, and treatment strategies for BRCA pathogenic variant carriers. 

Authors: Zhenzhen Zhang, Ph.D., of Oregon Health & Science University in Portland, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2024.7421)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

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Development and Validation of an 18-Gene Urine Test for High-Grade Prostate Cancer

Posted by Jim Michalski

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaoncology/fullarticle/10.1001/jamaoncol.2024.0455?guestAccessKey=29176ad0-6059-427e-b619-7fba71c6cc3a&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=041824

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Racial Discrimination and Metabolic Syndrome in Young Black Adults

Posted by Jim Michalski

JAMA Network Open

EMBARGOED FOR RELEASE: 11 A.M. (ET), THURSDAY, APRIL 18, 2024

Media advisory: The full study and commentary are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.5288?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=041824

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

 

About The Study: The findings of this study with 322 participants suggest that racial discrimination predisposes Black young adults to metabolic syndrome via sleep problems and inflammation, which may serve as actionable targets for prevention in minoritized populations that could reduce existing disparities and promote health equity. 

Authors: Nia Heard-Garris, M.D., M.B.A., M.Sc., of the Northwestern University Feinberg School of Medicine in Chicago, is the corresponding author. 

 

(doi:10.1001/jamanetworkopen.2024.5288)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

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