EMBARGOED FOR EARLY RELEASE: 3 P.M. (CT) SATURDAY, MAY 3, 2014 Media Advisory: To contact Dana Dabelea, M.D., Ph.D., call Tonya Ewers at 303-724-8573 or email tonya.ewers@ucdenver.edu. In a study that included data from more than three million children and adolescents from diverse geographic regions of the United States, researchers found that the prevalence of…
JAMA_OF:04302014
JAMA:04222014
Study Examines Effectiveness of Two Medications for Treating Epileptic Seizures In Children
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 22, 2014 Media Advisory: To contact James M. Chamberlain, M.D., call Joe Cantlupe at 202-476-4500 or email JCantlupe@childrensnational.org. Although some studies have suggested that the drug lorazepam may be more effective or safer than the drug diazepam in treating a type of epileptic seizures among children,…
Specialized Ambulance Improves Treatment Time For Stroke
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 22, 2014 Media Advisory: To contact Martin Ebinger, M.D., email martin.ebinger@charite.de. Using an ambulance that included a computed tomography (CT) scanner, point-of-care laboratory, telemedicine connection and a specialized prehospital stroke team resulted in decreased time to treatment for ischemic stroke, according to a study in the…
Study Examines Patient Preferences For Emergency Treatment of Stroke
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 22, 2014 Media Advisory: To contact Winston Chiong, M.D., Ph.D., call Laura Kurtzman at 415-476-3163 or email Laura.Kurtzman@ucsf.edu. The majority of adults surveyed indicated they would want administration of clot-dissolving medications if incapacitated by a stroke, a finding that supports clinicians’ use of this treatment if…
Medication Helps Improve Vision for Patients With Neurological Disorder
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 22, 2014 Media Advisory: To contact Michael Wall, M.D., call Jennifer Brown at 319- 356-7124 or email jennifer-l-brown@uiowa.edu. To contact editorial author Jonathan C. Horton, M.D., Ph.D., call Juliana Bunim at 415-476-8810 or email juliana.bunim@ucsf.edu. In patients with idiopathic intracranial hypertension and mild vision loss, the use…
Conservative Management of Vascular Abnormality in Brain Associated With Better Outcomes
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 22, 2014 Media Advisory: To contact Rustam Al-Shahi Salman, Ph.D., email Jen Middleton at jen.middleton@ed.ac.uk. Patients with arteriovenous malformations (abnormal connection between arteries and veins) in the brain that have not ruptured had a lower risk of stroke or death for up to 12 years if…
Quality Improvement Program Helps Lower Risk of Bleeding, Death Following Stroke
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 22, 2014 Media Advisory: To contact Gregg C. Fonarow, M.D., call Kim Irwin at 310-794-2262 or email kirwin@mednet.ucla.edu. To contact editorial author James C. Grotta, M.D., call Alex Rodriguez Loessin at 713-704-1222 or email alex.loessin@memorialhermann.org. In a study that included more than 71,000 stroke patients, implementation of…
JAMA:04152014
Thyroid Disease Risk Varies Among Blacks, Asians, and Whites
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 15, 2014 Media Advisory: To contact Donald S. A. McLeod, F.R.A.C.P., M.P.H., email donald.mcleod@qimrberghofer.edu.au. An analysis that included active military personnel finds that the rate of the thyroid disorder Graves disease is more common among blacks and Asian/Pacific Islanders compared with whites, according to a study…
Mothers with Higher BMI Have Increased Risk of Stillbirth, Infant Death
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 15, 2014 Media Advisory: To contact Dagfinn Aune, M.S., email d.aune@imperial.ac.uk. Higher maternal body mass index (BMI) before or in early pregnancy is associated with an increased risk of fetal death, stillbirth, and infant death, with women who are severely obese having the greatest risk of these…
JAMA:04082014
Study Examines Criteria for “Choosing Wisely” Lists of Least Beneficial Medical Services
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 8, 2014 Media Advisory: To contact Steven D. Pearson, M.D., M.Sc., call Molly Hooven at 301-594-5789 or email Molly.Hooven@nih.gov. In the creation of lists by specialty societies of medical services deemed least beneficial (the “Choosing Wisely” initiative), inclusion was often justified by evidence suggesting no additional benefit…
Comparison of Treatments for Advanced Lung Cancer Shows Chemotherapy May Be Best For Certain Patients
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 8, 2014 Media Advisory: To contact corresponding author Dong-Wan Kim, M.D., Ph.D., email kimdw@snu.ac.kr. Among patients with advanced non-small cell lung cancer without a mutation of a certain gene (EGFR), conventional chemotherapy, compared with treatment using epidermal growth factor receptor tyrosine kinase inhibitors, was associated with…
JAMA:04012014
Study Examines Potential Conflict of Interest for Leaders of Academic Medical Centers Serving on Pharmaceutical Boards
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 1, 2014 Media Advisory: To contact corresponding author Walid F. Gellad, M.D., M.P.H., call Allison Hydzik at 412-647-9975 or email hydzikam@upmc.edu. About 40 percent of pharmaceutical company boards of directors examined had at least one member who held a leadership position at an academic medical center, with…
Administering Blood Transfusions to Patients With Lower Levels of Hemoglobin Associated With Lower Risk of Serious Infection
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 1, 2014 Media Advisory: To contact corresponding author Mary A.M. Rogers, Ph.D., call Beata Mostafavi at 734- 764-2220 or email bmostafa@umich.edu. To contact editorial author Jeffrey L. Carson, M.D., call Jennifer Forbes at 732-235-6356 or email jenn.forbes@rwjms.rutgers.edu. Restricting red blood cell (RBC) transfusions among hospitalized patients…
Medication Does Not Help Prevent Erectile Dysfunction Following Radiation Therapy for Prostate Cancer
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 1, 2014 Media Advisory: To contact Thomas M. Pisansky, M.D., call Joe Dangor at 507-266-0696 or email dangor.yusuf@mayo.edu. Among men undergoing radiation therapy for prostate cancer, daily use of the erectile dysfunction drug tadalafil, compared with placebo, did not prevent loss of erectile function, according to a…
JAMA_OF:03312014
JAMA_OF:03312014
JAMA_03302014
Medication Does Not Reduce Risk of Recurrent Cardiovascular Events Among Patients With Diabetes
EMBARGOED FOR EARLY RELEASE: 7 A.M. (CT) SUNDAY, MARCH 30, 2014 Media Advisory: To contact A. Michael Lincoff, M.D., call Wyatt DuBois at 216-904-3344 or email DUBOISW@ccf.org. Use of the drug aleglitazar, which has shown the ability to lower glucose levels and have favorable effects on cholesterol, did not reduce the risk of cardiovascular…
JAMA_OF:03292014
Comparison of Drug-Releasing Stents Show Similar Safety Outcomes After Two Years
EMBARGOED FOR EARLY RELEASE: 9:45 A.M. (CT) MONDAY, MARCH 31, 2014 Media Advisory: To contact corresponding author Takeshi Kimura, M.D., email taketaka@kuhp.kyoto-u.ac.jp. A comparison of the safety of biodegradable polymer biolimus-eluting stents vs durable polymer everolimus-eluting stents finds similar outcomes for measures including death and heart attack after two years, according to a JAMA…
Metformin Does Not Improve Heart Function in Patients Without Diabetes
EMBARGOED FOR EARLY RELEASE: 7 A.M. (CT) MONDAY, MARCH 31, 2014 Media Advisory: To contact corresponding author Iwan C.C. van der Horst, M.D., Ph.D., email i.c.c.van.der.horst@umcg.nl. Although some research has suggested that metformin, a medication often used in the treatment of diabetes, may have favorable effects on ventricular (heart) function, among patients without diabetes who…
Comparison of Minimally Invasive Heart Valve Systems Finds Better Device Success with Balloon-Expandable Valve
EMBARGOED FOR EARLY RELEASE: 7 A.M. (CT) SUNDAY, MARCH 30, 2014 Media Advisory: To contact Mohamed Abdel-Wahab, M.D., email mohamed.abdel-wahab@segebergerkliniken.de. To contact editorial co-author E. Murat Tuzcu, M.D., call Wyatt DuBois at 216-904-3344 or email DUBOISW@ccf.org. Among patients undergoing aortic valve replacement using a catheter tube, a comparison of two types of heart valve technologies,…
Analysis Supports Use of Risk Equations to Guide Statin Therapy
EMBARGOED FOR EARLY RELEASE: 1 P.M. (CT) SATURDAY, MARCH 29, 2014 Media Advisory: To contact Paul Muntner, Ph.D., call Nicole Wyatt at 205-934-8938 or email nwyatt@uab.edu. In an analysis of almost 11,000 patients, an assessment of equations that help guide whether a patient should begin taking a statin (cholesterol lowering medication) found that observed and…
U.S., European Cholesterol Guidelines Differ in Statin Use Recommendations
EMBARGOED FOR EARLY RELEASE: 1 P.M. (CT) SATURDAY, MARCH 29, 2014 Media Advisory: To contact Maryam Kavousi, M.D., Ph.D., email m.kavousi@erasmusmc.nl. Application of U.S. and European cholesterol guidelines to a European population found that proportions of individuals eligible for statins differed substantially, with one U.S. guideline recommending statins for nearly all men and two-thirds…
Study Estimates Proportion of Adults Affected by New Blood Pressure Guideline
EMBARGOED FOR EARLY RELEASE: 1 P.M. (CT) SATURDAY, MARCH 29, 2014 Media Advisory: To contact Ann Marie Navar-Boggan, M.D., Ph.D., call Sarah Avery at 919-724-5343 or email sarah.avery@duke.edu. To contact editorial author Harlan M. Krumholz, M.D., S.M., call Karen Peart at 203-432-1326 or email karen.peart@yale.edu. Applying the updated 2014 blood pressure (BP) guideline to the…
JAMA:03252014
Study Finds Substantial Decrease in Use of Cardiac Imaging Procedure
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 25, 2014 Media Advisory: To contact Edward J. McNulty, M.D., call Janet Byron at 510-891-3115 or email Janet.L.Byron@kp.org. Chicago –There has been a sharp decline since 2006 in the use of nuclear myocardial perfusion imaging (MPI; an imaging procedure used to determine areas of the heart with…
Blood Glucose Measure Appears to Provide Little Benefit in Predicting Risk of Cardiovascular Disease
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 25, 2014 Media Advisory: To contact corresponding author John Danesh, F.R.C.P., email erfc@phpc.cam.ac.uk. Chicago – In a study that included nearly 300,000 adults without a known history of diabetes or cardiovascular disease (CVD), adding information about glycated hemoglobin (HbA1c), a measure of longer-term blood sugar control,…
Greater Distance From Transplant Center Associated With Lower Likelihood of Receiving Liver Transplant, Higher Risk of Death Among U.S. Veterans
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 25, 2014 Media Advisory: To contact David S. Goldberg, M.D., M.S.C.E., call Lee-Ann Donegan at 215-349-5660 or email leeann.donegan@uphs.upenn.edu. Chicago – Among veterans meeting eligibility for liver transplantation, greater distance from a Veterans Affairs transplant center or any transplant center was associated with lower likelihood of being…
Web-based Alcohol Screening Program Shows Limited Effect Among University Students
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 25, 2014 Media Advisory: To contact Kypros Kypri, Ph.D., email kypros.kypri@newcastle.edu.au. To contact editorial co-author Timothy S. Naimi, M.D., M.P.H., call Gina DiGravio at 617-638-8480 or email gina.digravio@bmc.org. Chicago – Among university students in New Zealand, a web-based alcohol screening and brief intervention program produced a modest…
Treatment Helps Reduce Risk of Esophagus Disorder Progressing to Cancer
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 25, 2014 Media Advisory: To contact corresponding author Jacques J. Bergman, M.D., Ph.D., email j.j.bergman@amc.uva.nl. To contact editorial author Klaus Monkemuller, M.D., Ph.D., F.A.S.G.E., call Tyler Greer at 205-934-2041 or email tgreer@uab.edu. Chicago – Among patients with the condition known as Barrett esophagus, treatment of abnormal…
JAMA_OF:03182014
Study Finds Risk of Death Among ICU Patients With Severe Sepsis Has Decreased
EMBARGOED FOR EARLY RELEASE: 3:30 A.M. (CT) TUESDAY, MARCH 18, 2014 Media Advisory: To contact corresponding author Rinaldo Bellomo, M.D., Ph.D., email Rinaldo.BELLOMO@austin.org.au. To contact editorial co-author Theodore J. Iwashyna, M.D., Ph.D., call Shantell Kirkendoll at 734-764-2220 or email SMKIRK@UMICH.EDU. Chicago – In critically ill patients in Australia and New Zealand with severe sepsis…
JAMA:03182014
Pregnancy Associated With Greater Risk of Certain Bacterial Infection, Which May Worsen Outcomes
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 18, 2014 Media Advisory: To contact corresponding author Shamez N. Ladhani, M.R.C.P.C.H., Ph.D., email Shamez.Ladhani@phe.gov.uk. To contact editorial author Morven S. Edwards, M.D., call Glenna Picton at 713-798-7973 or email picton@bcm.edu. Chicago – In a surveillance study of infection with the bacterium Haemophilus influenzae among women of…
Children With Glomerular Kidney Disease More Likely to Have Hypertension as Adults
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 18, 2014 Media Advisory: To contact Asaf Vivante, M.D., email asafvivante@gmail.com. Chicago – Men who as children had glomerular disease, a disorder of the portion of the kidney that filters blood and one that usually resolves with time, were more likely than men without childhood glomerular…
Using Age to Distinguish Normal From Abnormal Blood Test Results Appears to Safely Exclude Lung Blood Clots in Older Patients
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 18, 2014 Media Advisory: To contact Marc Righini, M.D., email Marc.Righini@hcuge.ch. Chicago – Using a patient’s age to raise the threshold for an abnormal result of a blood test used to assess patients with a suspected pulmonary embolism (blood clot in lungs) appeared to be safe…
Risk of Psychiatric Diagnoses, Medication Use Increases after Critical Illness
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 18, 2014 Media Advisory: To contact corresponding author Christian F. Christiansen, M.D., Ph.D., email cc@dce.au.dk. Chicago – Critically ill patients receiving mechanical ventilation had a higher prevalence of prior psychiatric diagnoses and an increased risk of a new psychiatric diagnosis and medication use after hospital discharge,…
JAMA:03112014
Study Examines Development of Peer Review Research in Biomedicine
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 11, 2014 Media Advisory: To contact corresponding author Ana Marusic, M.D., Ph.D., email ana.marusic@mefst.hr. To contact editorial co-author Annette Flanagin, R.N., M.A., call Jim Michalski at 312-464-5785 or email jim.michalski@jamanetwork.org. Chicago – An analysis of research on peer review finds that studies aimed at improving methods…
Research Finds Discrepancies Between Trial Results Reported on Clinical Trial Registry and in High-Impact Journals
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 11, 2014 Media Advisory: To contact corresponding author Joseph S. Ross, M.D., M.H.S., call Karen Peart at 203-432-1326 or email karen.peart@yale.edu. Chicago – During a one year period, among clinical trials published in high-impact journals that reported results on a public clinical trial registry (ClinicalTrials.gov), nearly all…
Discontinuation of Randomized Clinical Trials Common
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 11, 2014 Media Advisory: To contact corresponding author Matthias Briel, M.D., M.Sc., email matthias.briel@usb.ch. Chicago – Approximately 25 percent of about 1,000 randomized clinical trials initiated between 2000 and 2003 were discontinued, with the most common reason cited being poor recruitment of volunteers; and less than…
Study Finds Comparable Outcomes For Commonly Used Surgeries to Treat Vaginal Prolapse
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 11, 2014 Media Advisory: To contact Matthew D. Barber, M.D., M.H.S., call Halle Bishop Weston at 216-445-8592 or email bishoph@ccf.org. Chicago – For women undergoing surgery for vaginal prolapse and stress urinary incontinence, neither of 2 common repair procedures was superior to the other for functional or…
Findings Indicate Technical Challenges Remain Before Reliably Using Whole-Genome Sequencing For Clinical Applications
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 11, 2014 Media Advisory: To contact corresponding authors Euan A. Ashley, M.R.C.P., D.Phil., or Thomas Quertermous, M.D., call Krista Conger at 650-725-5271 or email kristac@stanford.edu. To contact editorial author William Gregory Feero, M.D., Ph.D., call 207-453-3030 or email w.gregory.feero@mainegeneral.org. Chicago – In an exploratory study involving 12…
JAMA:03042014
Study Examines Gap in Federal Oversight of Clinical Trials
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 4, 2014 Media Advisory: To contact Deborah A. Zarin, M.D., call Kathleen Cravedi at 301-496-6308 or email Kcravedi@nlm.nih.gov. Chicago – An analysis of nearly 24,000 active human research clinical trials found that between 5 percent and 16 percent fall into a regulatory gap and are not covered…
Anti-Coagulant Treatment For Atrial Fibrillation Does Not Worsen Outcomes for Patients With Kidney Disease
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 4, 2014 Media Advisory: To contact Juan Jesus Carrero, Ph.D., email Juan.Jesus.Carrero@ki.se. To contact editorial co-author Wolfgang C. Winkelmayer, M.D., M.P.H., Sc.D., call Tracie White at 650-723-7628 or email traciew@stanford.edu. Chicago – Although some research has suggested that the use of the anticoagulant warfarin for atrial fibrillation…
Opening or Expanding a Casino Associated With Lower Rate of Overweight Children in that Community
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 4, 2014 Media Advisory: To contact Jessica C. Jones-Smith, Ph.D., call Brandon Howard at 410-502-9059 or email bhoward@jhsph.edu. To contact editorial author Neal Halfon, M.D., M.P.H., call Amy Albin at 310-794-8672 or email aalbin@mednet.ucla.edu. Chicago – The opening or expansion of a casino in a community is…
Moving Out of High Poverty Appears to Affect the Mental Health of Boys, Girls Differently
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 4, 2014 Media Advisory: To contact Ronald C. Kessler, Ph.D., call David Cameron at 617-432-0441 or email david_cameron@hms.harvard.edu. Chicago – For families who moved out of high-poverty neighborhoods, boys experienced an increase and girls a decrease in rates of depression and conduct disorder, according to a study…
JAMA:02252014
Continuous Handling of Receipts Linked to Higher Urine BPA Levels
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 25, 2014 Media Advisory: To contact Shelley Ehrlich, M.D., Sc.D., M.P.H., call Jim Feuer at 513-636-4656 or email Jim.Feuer@cchmc.org. Chicago – Study participants who handled receipts printed on thermal paper continuously for 2 hours without gloves had an increase in urine bisphenol A (BPA) concentrations compared…
Blood Transfusion For Patients Undergoing PCI Associated With Increased Risk of In-Hospital Cardiac Event
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 25, 2014 Media Advisory: To contact Matthew W. Sherwood, M.D, call Sarah Avery at 919-660-1306 or email sarah.avery@duke.edu. Chicago – In an analysis that included more than two million patients who underwent a percutaneous coronary intervention (PCI; procedures such as balloon angioplasty or stent placement used…
Patient-Centered Medical Home Program Led to Little Improvement in Quality and No Reduction in Use of Services, Total Costs
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 25, 2014 Media Advisory: To contact Mark W. Friedberg, M.D., M.P.P., call Warren Robak at 310-451-6913 or email robak@rand.org. To contact editorial author Thomas L. Schwenk, M.D., call Anne McMillin at 775-682-9254 or email amcmillin@medicine.nevada.edu. Chicago – One of the first, largest, and longest-running multipayer trials of…
Receipt of Live MMR Vaccine Associated With Lower Rate of Infection-Related Hospital Admissions For Children
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 25, 2014 Media Advisory: To contact Signe Sorup, Ph.D., email sgs@ssi.dk. To contact editorial co-author David Goldblatt, M.B.Ch.B., Ph.D., email d.goldblatt@ucl.ac.uk. Chicago – In a nationwide group of Danish children, receipt of the live measles, mumps, and rubella (MMR) vaccine on schedule after vaccination for other…
Obesity Prevalence Remains High in U.S.; No Significant Change in Recent Years
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 25, 2014 Media Advisory: To contact Cynthia L. Ogden, Ph.D., email Jeff Lancashire (jhl1@cdc.gov) or the CDC press office (paoquery@cdc.gov) or call 301-458-4800. Chicago – The prevalence of obesity remains high in the U.S., with about one-third of adults and 17 percent of children and teens obese…
JAMA:02182014
Study Finds Low Rate of Surgical Site Infections Following Ambulatory Surgery
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 18, 2014 Media Advisory: To contact corresponding author Claudia A. Steiner, M.D., M.P.H., call Alison Hunt at 301-427-1244 or email Alison.Hunt@ahrq.hhs.gov. Chicago – In an analysis that included nearly 300,000 patients from eight states who underwent ambulatory surgery (surgery performed on a person who is admitted to…
Study Examines Public Awareness, Use of Online Physician Rating Sites
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 18, 2014 Media Advisory: To contact David A. Hanauer, M.D., M.S., call Mary Masson at 734-764-2220 or email mfmasson@med.umich.edu. Chicago – In a survey of a nationally representative sample of the U.S. population, 65 percent of respondents reported awareness of online physician ratings and about one-fourth reported…
Treatment Using Electrical Energy, Instead of Medications, May Be Viable First Option for Treating Certain Type of Atrial Fibrillation
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 18, 2014 Media Advisory: To contact Carlos A. Morillo, M.D., F.R.C.P.C., call Veronica McGuire at 905-525-9140, ext. 22169, or email vmcguir@mcmaster.ca. To contact editorial co-author Hugh Calkins, M.D., call Stephanie Desmon at 410-955-8665 or email sdesmon1@jhmi.edu. Chicago – Among patients with untreated paroxysmal (intermittent) atrial fibrillation…
Medication to Treat Agitation for Alzheimer Disease Shows Mixed Results
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 18, 2014 Media Advisory: To contact Anton P. Porsteinsson, M.D., call Julie Philipp at 585-275-1309 or email Julie_Philipp@urmc.rochester.edu. To contact editorial author Gary W. Small, M.D., call Rachel Champeau at 310-794-2270 or email rchampeau@mednet.ucla.edu. Chicago – The use of the medication citalopram was associated with a reduction…
Home-Based Exercise Program Improves Recovery Following Rehabilitation for Hip Fracture
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 18, 2014 Media Advisory: To contact Nancy K. Latham, Ph.D., P.T., call Lisa Chedekel at 617-571-6370 or email chedekel@bu.edu. Chicago – Among patients who had completed standard rehabilitation after hip fracture, the use of a home exercise program that included exercises such as standing from a chair…
JAMA: 02112014
Study Examines Legislative Challenges to School Immunization Mandates
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 11, 2014 Media Advisory: To contact Saad B. Omer, M.B.B.S., M.P.H., Ph.D., call Melva Robertson at 404-727-5692 or email melva.robertson@emory.edu. Chicago – From 2009-2012, 36 bills introduced in 18 states sought to modify school immunization mandates, with the majority seeking to expand exemptions although none of the…
Hospital Readmission Rate Varies Following Care at Rehabilitation Facility
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 11, 2014 Media Advisory: To contact Kenneth J. Ottenbacher, Ph.D., call Molly Dannenmaier at 409-772-8790 or email mjdannen@utmb.edu; or Mechal Weiss at 212-642-7731, mechal.weiss@edelman.com. Chicago – Among rehabilitation facilities providing services to Medicare fee-for-service patients, 30-day hospital readmission rates vary, from about 6 percent for patients with…
Fewer Doses of HPV Vaccine Still Results in Reduced Risk of STD
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 11, 2014 Media Advisory: To contact corresponding author Lisen Arnheim-Dahlström, Ph.D., email lisen.arnheim.dahlstrom@ki.se. Chicago – Although maximum reduction in the risk of genital warts (condylomata) was seen after 3 doses of human papillomavirus (HPV) vaccine, receipt of 2 vaccine doses was associated with considerable reduction in risk,…
Preterm Infants More Likely to Have Elevated Insulin Levels in Early Childhood
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 11, 2014 Media Advisory: To contact corresponding author Xiaobin Wang, M.D., M.P.H., Sc.D., call Tim Parsons at 410-955-7619 or email tmparson@jhsph.edu. To contact editorial author Mark Hanson, D.Phil., F.R.C.O.G., email M.Hanson@soton.ac.uk. Chicago – Researchers have found that preterm infants are more likely to have elevated insulin levels…
Study Finds Small Increased Risk of Kidney Disease Following Kidney Donation
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 11, 2014 Media Advisory: To contact corresponding author Dorry L. Segev, M.D., Ph.D., call Stephanie Desmon at 410-955-8665 or email sdesmon1@jhmi.edu. To contact editorial co-author John S. Gill, M.D., call Brian Kladko at 604-827-3301 or email brian.kladko@ubc.ca. Chicago – An analysis of nearly 100,000 kidney donors…
JAMA:02042014
Pre-Term Infants with Severe Retinopathy More Likely to Have Non-Visual Disabilities at Age 5
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 4, 2014 Media Advisory: To contact Barbara Schmidt, M.D., M.Sc., call Alison Fraser at 267-426-6054 or email FraserA1@email.chop.edu. Chicago – In a group of very low-birth-weight infants, severe retinopathy of prematurity was associated with nonvisual disabilities at age 5 years, according to a study in the February…
Non-Invasive Measure of Heart Tissue Scarring May Be Useful For Determining Patients Most Suitable For Procedure for Irregular Heart Beat
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 4, 2014 Media Advisory: To contact Nassir F. Marrouche, M.D., call Phil Sahm at 801-581-2517 or email phil.sahm@hsc.utah.edu. Chicago – Scarring of tissue in the upper chamber of the heart (atrium) was associated with recurrent rhythm disorder after treatment, according to a study in the February 5…
Pattern of Higher Blood Pressure in Early Adulthood Helps Predict Risk of Atherosclerosis in Middle-Age
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 4, 2014 Media Advisory: To contact Norrina B. Allen, Ph.D., M.P.H., call Marla Paul at 312-503-8928 or email marla-paul@northwestern.edu. To contact editorial co-author George L. Bakris, M.D., call John Easton at 773-795-5225 or email john.easton@uchospitals.edu. Chicago – In an analysis of blood pressure patterns over a 25-year…
JAMA_OF:01212014
Oral History Examines Origins, Development and Future of Evidence-Based Medicine
EMBARGOED FOR EARLY RELEASE: 8 A.M. (CT) TUESDAY, JANUARY 21, 2014 Media Advisory: To contact Richard Smith, M.B.Ch.B., C.B.E., email richardswsmith@yahoo.co.uk. Chicago – A video of individuals who gave birth to the evidence-based medicine movement features valuable oral histories of the movement, according to an editorial in the January 22/29 issue of JAMA. Evidence-based…
JAMA:01212014
Biomarkers in Blood Show Potential As Early Detection Method of Pancreatic Cancer
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 21, 2014 Media Advisory: To contact corresponding author Julia S. Johansen, M.D., D.M.Sc., email julia.johansen@post3.tele.dk. To contact editorial co-author Donald J. Buchsbaum, Ph.D., email Beena Thannickal at beenat@uab.edu. Chicago – Researchers have identified diagnostic microRNA panels in whole blood that had the ability to distinguish, to some…
Mediterranean Diet Associated With Lower Risk of Peripheral Artery Disease
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 21, 2014 Media Advisory: To contact corresponding author Miguel A. Martinez-Gonzalez, M.D., M.P.H., Ph.D., email mamartinez@unav.es. Chicago – A multicenter study that previously reported a reduction in heart attack and stroke with a Mediterranean diet supplemented with extra-virgin olive oil or with nuts now also reports…
Study Examines Reasons for Delay, Denial of New Drugs by FDA
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 21, 2014 Media Advisory: To contact Leonard V. Sacks, M.B.B.Ch., call Sandy Walsh at 301-796-4669 or email sandy.walsh@fda.hhs.gov. Chicago – Several potentially preventable deficiencies, including failure to select optimal drug doses and suitable outcome measures for a study, accounted for significant delays in the approval of new…
Many Cardiovascular Devices Approved by Process That Often Does Not Require New Clinical Data
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 21, 2014 Media Advisory: To contact corresponding author Aaron S. Kesselheim, M.D., J.D., M.P.H., call Jessica Maki at 617-525-6373 or email jmaki3@partners.org. Chicago – Many cardiac implantable electronic device models currently in use were approved via a Food and Drug Administration review process in which the…
Wide Variation Found in Quality of Evidence Used By FDA For Approval of New Drugs
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 21, 2014 Media Advisory: To contact corresponding author Joseph S. Ross, M.D., M.H.S., call Karen Peart at 203-432-1326 or email karen.peart@yale.edu. To contact editorial co-author Steven N. Goodman, M.D., M.H.S., Ph.D., call Ruthann Richter at 650-725-8047 or email richter1@stanford.edu. Chicago – Clinical trials used by the Food…
JAMA:01142014
Patients With Mild Hyperglycemia and Genetic Mutation Have Low Prevalence of Vascular Complications
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 14, 2014 Media Advisory: To contact corresponding author Andrew T. Hattersley, D.M., email a.t.hattersley@exeter.ac.uk. To contact editorial author Jose C. Florez, M.D., Ph.D., call Mike Morrison at 617-724-6425 or email mdmorrison@partners.org. Chicago – Despite having mild hyperglycemia for approximately 50 years, patients with a mutation in the…
Follow-up Tests Improve Colorectal Cancer Recurrence Detection
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 14, 2014 Media Advisory: To contact corresponding author John N. Primrose, M.D., F.R.C.S., email j.n.primrose@soton.ac.uk. Chicago – Among patients who had undergone curative surgery for primary colorectal cancer, the screening methods of computed tomography and carcinoembryonic antigen each provided an improved rate of surgical treatment of cancer…
JAMA:01072014
Study Examines Prevalence of Smoking Among Health Care Professionals
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 7, 2014 Media Advisory: To contact Linda Sarna, Ph.D., R.N., call Laura Perry at 818-212-6226 or email Lperry@sonnet.ucla.edu. Chicago – A survey of health care professionals finds that in 2010-2011, current smoking among this group, except for licensed practical nurses, was lower than the general population,…
Longer-Term Use of Smoking Cessation Medication Effective Among Patients With Mental Illness
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 7, 2014 Media Advisory: To contact A. Eden Evins, M.D., M.P.H., email Kristen Chadwick at kschadwick@partners.org. Chicago – Among smokers with schizophrenia or bipolar disease who achieved initial smoking abstinence with a standard 12-week course of the smoking cessation drug varenicline, an additional 40 weeks of treatment…
Combination Therapy Shows Short-Term Benefit, But Does Not Improve Ability to Quit Smoking After One Year
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 7, 2014 Media Advisory: To contact Jon O. Ebbert, M.D., M.Sc., call Kelley Luckstein at 507-284-5005 or email luckstein.kelley@mayo.edu. Chicago – Among cigarette smokers, the combined use of the smoking cessation medications varenicline and bupropion, compared with varenicline alone, resulted in better rates of smoking abstinence at…
Adults With Mental Illness Have Lower Rate of Decline in Smoking
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 7, 2014 Media Advisory: To contact Benjamin Lê Cook, Ph.D., M.P.H., call David Cecere at 617-591-4044 or email dcecere@challiance.org. Chicago – In recent years, the decline in smoking among individuals with mental illness was significantly less than among those without mental illness, although the rates of quitting…
Overall Prevalence of Smoking Has Decreased Globally, Although Number of Smokers, Cigarettes Consumed, Has Increased
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 7, 2014 Media Advisory: To contact corresponding author Christopher J.L. Murray, M.D., D.Phil., call Rhonda Stewart at 206-897-2863 or email stewartr@uw.edu. Chicago – Since 1980, the global prevalence of daily tobacco smoking has declined by an estimated 25 percent for men and 42 percent for women, although…
Study Estimates Tobacco Control in U.S. Has Saved 8 Million Lives In Last 50 Years
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 7, 2014 Media Advisory: To contact Theodore R. Holford, Ph.D., call Helen Dodson at 203-436-3984 or email helen.dodson@yale.edu. Chicago – Researchers estimate that tobacco control in the U.S. since 1964 has been associated with the avoidance of an estimated 8 million premature smoking-attributable deaths, with the beneficiaries…
JAMA:12312013
Study Identifies Factors Associated With Pain One Year After Breast Cancer Surgery
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, DECEMBER 31, 2013 Media Advisory: To contact Tuomo J. Meretoja, M.D., Ph.D., email tuomo.meretoja@fimnet.fi. Chicago – In a study that included more than 800 women who had undergone surgery for breast cancer, the majority reported some level of pain 12 months after surgery, and factors associated with…
Use of Vitamin E By Patients With Mild to Moderate Alzheimer Disease Slows Functional Decline
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, DECEMBER 31, 2013 Media Advisory: To contact Maurice W. Dysken, M.D., call Ralph Heussner at 612-467-3012 or email Ralph.Heussner@va.gov. To contact editorial co-author Denis A. Evans, M.D., email Deb Song at Deb_Song@rush.edu. Chicago – Among patients with mild to moderate Alzheimer disease, a daily dosage of 2,000…
JAMA:12242013
Nonsteroidal Anti-Inflammatory Agent Slows Rate of Progression of Neurodegenerative Disease
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, DECEMBER 24, 2013 Media Advisory: To contact John L. Berk, M.D., call Jenny Eriksen Leary at 617-638-6841 or email jenny.eriksen@bmc.org. Chicago – Among patients with familial amyloid polyneuropathy, a lethal, genetic neurodegenerative disease, use of the nonsteroidal anti-inflammatory agent diflunisal compared with placebo for 2 years reduced the…