For The Media – JAMA Network

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JUNE 25, 2013 Media Advisory: To contact Gabriela Ilie, Ph.D., call Leslie Shepherd at 416-864-6094 or email shepherdl@smh.ca. “Traumatic brain injury (TBI) among adolescents has been identified as an important health priority. However, studies of TBI among adolescents in large representative samples are lacking. This information is important…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JUNE 25, 2013 Media Advisory: To contact corresponding author Andrew T. Chan, M.D., M.P.H., call Jessica Maki at 617-534-1603 or email jmaki3@partners.org; for corresponding author Shuji Ogino, M.D., Ph.D., M.S., call Anne Doerr at 617-632-5665 or email anne_doerr@dfci.harvard.edu. To contact editorial author Boris Pasche, M.D., Ph.D., call Beena…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JUNE 25, 2013 Media Advisory: To contact corresponding author Brent K. Hollenbeck, M.D., M.S., call Justin Harris at 734-764-2220 or email juaha@umich.edu. CHICAGO – Use of advanced treatment technologies for prostate cancer, such as intensity-modulated radiotherapy and robotic prostatectomy, has increased among men with low-risk disease, high risk…

EMBARGOED FOR EARLY RELEASE: 10:30 A.M. (CT) MONDAY, JUNE 24, 2013 Media Advisory: To contact Karen E. Joynt, M.D., M.P.H., call Marge Dwyer at 617-432-8416 or email mhdwyer@hsph.harvard.edu. To contact editorial co-author Aaron E. Carroll, M.D., M.S., call Mary Hardin at 317-274-5456 or email mhardin@iu.edu. CHICAGO – In an analysis that included a sample of…

EMBARGOED FOR EARLY RELEASE: 8 A.M. (CT) SUNDAY, JUNE 23, 2013 Media Advisory: To contact Sandra L. Decker, Ph.D., call Jeff Lancashire at 301-458-4800 or email jhl1@cdc.gov. To contact co-author Genevieve M. Kenney, Ph.D., call 202-261-5568 or email jkenney@urban.org. CHICAGO – Compared with adults already enrolled in Medicaid, low-income uninsured adults who may be eligible…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JUNE 18, 2013 Study Finds Need for Improvement on State Health Care Price Websites “With rising health care costs and 30 percent of privately insured adults enrolled in high-deductible health care plans, calls for greater health care price transparency are increasing. In response, health plans, consumer groups, and…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JUNE 18, 2013 Media Advisory: To contact corresponding author Jouke T. Annema, M.D., Ph.D., email j.t.annema@amc.nl. CHICAGO – Among patients with suspected stage I/II pulmonary sarcoidosis who were undergoing confirmation of the condition via tissue sampling, the use of the procedure known as endosonographic nodal aspiration compared with…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JUNE 18, 2013 Media Advisory: To contact Anette G. Ziegler, M.D., email anette-g.ziegler@helmholtz-muenchen.de. To contact editorial co-author Jay S. Skyler, M.D., call Lisa Worley at 305-243-5184 or email lworley2@med.miami.edu. CHICAGO – The majority of children at risk of type 1 diabetes who developed 2 or more diabetes-related autoantibodies…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JUNE 18, 2013 Media Advisory: To contact Marloes W. Heijstek, M.D., email m.w.heijstek@umcutrecht.nl. CHICAGO – Among children with juvenile idiopathic arthritis (JIA) who had undergone primary immunization, the use of a measles-mumps-rubella (MMR) booster compared with no booster did not result in worse JIA disease activity, according to…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JUNE 18, 2013 Media Advisory: To contact Anurag N. Malani, M.D., call Laura Blodgett at 734-712-4536 or email blodgetl@trinity-health.org. To contact editorial co-author Thomas F. Patterson, M.D., call Sheila Hotchkin at 210-567-3026 or email Hotchkin@uthscsa.edu. CHICAGO – Magnetic resonance imaging (MRI) at the site of injection of a…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JUNE 18, 2013 Media Advisory: To contact Jeffrey L. Saver, M.D., call Kim Irwin at 310-794-2262 or email kirwin@mednet.ucla.edu; or call Rachel Champeau at 310-794-2270 or email rchampeau@mednet.ucla.edu. CHICAGO – In a study that included nearly 60,000 patients with acute ischemic stroke, thrombolytic treatment (to help dissolve a…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JUNE 11, 2013 Hearing Loss Associated With Hospitalization, Poorer Self-Reported Health “Hearing loss (HL) is a chronic condition that affects nearly 2 of every 3 adults aged 70 years or older in the United States. Hearing loss has broader implications for older adults, being independently associated with poorer…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JUNE 11, 2013 Media Advisory: To contact corresponding author Borge G. Nordestgaard, D.M.Sc., email Boerge.Nordestgaard@regionh.dk. To contact editorial co-author Sanjay Sethi, M.D., call Ellen Goldbaum at 716-645-4605 or email goldbaum@buffalo.edu. CHICAGO – Simultaneously elevated levels of the biomarkers C-reactive protein, fibrinogen and leukocyte count in individuals with chronic…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JUNE 11, 2013 Media Advisory: To contact Sven Cnattingius, M.D., Ph.D., email sven.cnattingius@ki.se. CHICAGO – In a study that included more than 1.5 million deliveries in Sweden, maternal overweight and obesity during pregnancy were associated with increased risk for preterm delivery, with the highest risks observed for extremely…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JUNE 11, 2013 Media Advisory: To contact Melissa M. Hudson, M.D., call Summer Freeman at 901-595-3061 or email summer.freeman@stjude.org. CHICAGO – In an analysis that included more than 1,700 adult survivors of childhood cancer, researchers found a very high percentage of survivors with 1 or more chronic health…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JUNE 11, 2013 Media Advisory: To contact Jeffrey S. Gerber, M.D., Ph.D., call Rachel Salis-Silverman at 267-426-6063 or email Salis@email.chop.edu. To contact editorial author Jonathan A. Finkelstein, M.D., M.P.H., call Meghan Weber at 617-919-3656 or email Meghan.Weber@childrens.harvard.edu. CHICAGO – An intervention consisting of clinician education coupled with personalized…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JUNE 4, 2013 Research Finds Retinal Vessel Leakage During High Altitude Exposure “Exposure to high altitude can cause acute mountain sickness (AMS) and, in severe cases, cerebral or pulmonary edema. Capillary leakage has been hypothesized to play a role in the pathogenesis of AMS, although the mechanism of…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JUNE 4, 2013 Media Advisory: To contact Melinda Maggard-Gibbons, M.D., M.S.H.S., call Warren Robak at 310-451-6913 or email robak@rand.org. CHICAGO – A review of more than 50 studies found limited evidence supporting the use of bariatric surgical procedures for non-morbidly obese adults (body mass index [BMI] 30-35) with…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JUNE 4, 2013 Media Advisory: To contact Sayeed Ikramuddin, M.D., call Matt DePoint at 612-625-4110 or email mdepoint@umn.edu. To contact editorial author Bruce M. Wolfe, M.D., call Mirabai Vogt at 503-494-7986 or email vogtmi@ohsu.edu. CHICAGO – Among mild to moderately obese patients with type 2 diabetes, adding gastric…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MAY 21, 2013 Advances in Regulatory Science at the Food and Drug Administration In this Viewpoint, Bruce M. Psaty, M.D., Ph.D., of the University of Washington, Seattle, and colleagues discuss advances in recent years at the U.S. Food and Drug Administration (FDA) to improve drug evaluation. “The mark…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MAY 21, 2013 Media Advisory: To contact Duncan Young, D.M., email duncan.young@nda.ox.ac.uk. To contact editorial author Derek C. Angus, M.D., M.P.H., call Rick Pietzak at 412-864-4151 or email pietzakr@upmc.edu. CHICAGO – For critically ill patients receiving mechanical ventilation, early tracheostomy (within the first 4 days after admission) was…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MAY 21, 2013 Media Advisory: To contact Wei Jiang, M.D., call Rachel Harrison at 919-419-5069 or email rachel.harrison@duke.edu. CHICAGO – Among patients with stable coronary heart disease and mental stress-induced myocardial ischemia (MSIMI), 6 weeks of treatment with the antidepressant escitalopram, compared with placebo, resulted in a lower…

EMBARGOED FOR EARLY RELEASE: 1:00 P.M. (CT) TUESDAY, MAY 21, 2013 Media Advisory: To contact corresponding author David A. Schwartz, M.D., call Mark Couch at 303-724-5377 or email Mark.Couch@ucdenver.edu. CHICAGO – Variation in the gene MUC5B among patients with idiopathic pulmonary fibrosis was associated with improved survival, according to a study published online by JAMA….

EMBARGOED FOR EARLY RELEASE: 1:00 P.M. (CT) TUESDAY, MAY 21, 2013 Media Advisory: To contact Jorg D. Leuppi, M.D., Ph.D., email joerg.leuppi@ksli.ch. To contact editorial co-author Don D. Sin, M.D., call Justin Karasick at 604-806-8460 or email jkarasick@providencehealth.bc.ca. CHICAGO – Among patients with acute exacerbations of chronic obstructive pulmonary disease (COPD) requiring hospital admission, a…

EMBARGOED FOR EARLY RELEASE: 1:00 P.M. (CT) MONDAY, MAY 20, 2013 Media Advisory: To contact Gordon S. Doig, Ph.D., email gdoig@med.usyd.edu.au. To contact editorial co-author Juan B. Ochoa Gautier, M.D., call Rick Pietzak at 412-864-4151 or email pietzakr@upmc.edu. CHICAGO – The early (within 24 hours of intensive care unit [ICU] admission) provision of intravenous nutrition…

EMBARGOED FOR EARLY RELEASE: 1:00 P.M. (CT) MONDAY, MAY 20, 2013 Media Advisory: To contact Linda L. Chlan, Ph.D., R.N., call Kathryn Kelley at 614-688-1062 or email kelley.81@osu.edu. To contact editorial co-author Elie Azoulay, M.D., Ph.D., email elie.azoulay@sls.aphp.fr. CHICAGO – Among intensive care unit patients receiving acute ventilatory support for respiratory failure, use of patient-preferred…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MAY 14, 2013 No Significant Change Seen in Overall Smokeless Tobacco Use Among U.S. Youths Tobacco use remains the leading preventable cause of death and disease in the United States. Declines in smoking among youths were observed from the late 1990s. “However, limited information exists on trends in…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MAY 14, 2013 Media Advisory: To contact Ingrid Nygaard, M.D., call Phil Sahm at 801-581-2517 or email phil.sahm@hsc.utah.edu. To contact editorial author Cheryl B. Iglesia, M.D., call Karen Mallet at 215-514-9751 or email km463@georgetown.edu. CHICAGO – Results after seven years of follow-up suggest that women considering abdominal sacrocolpopexy…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MAY 14, 2013 Media Advisory: To contact Pamela N. Peterson, M.D., M.S.P.H., call Jenny Bertrand at 303-602-4924 or email Jennifer.bertrand@dhha.org. CHICAGO – Even though patients receiving an implantable cardioverter-defibrillator (ICD) for primary prevention often receive a dual-chamber ICD, an analysis that included more than 32,000 patients receiving an…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MAY 7, 2013 Media Advisory:  To contact Jeffrey Ecker, M.D., call Susan McGreevey at 617-724-2764 or email: smcgreevey@partners.org   CHICAGO – A Clinical Crossroads review article in the May 8 issue of JAMA discusses the potential benefits and risks for pregnant women who request cesarean delivery without an…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MAY 7, 2013 Study Finds Increase in Fall-Related Traumatic Brain Injuries Among Elderly Men and Women “Traumatic brain injury (TBI) is a major cause of hospitalization, disability, and death-worldwide, and among older adults, falling is the most common cause of TBI,” writes Niina Korhonen, B.M., of the Injury…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MAY 7, 2013 Media Advisory: To contact corresponding author Markus M. Lerch, M.D., F.R.C.P., email lerch@uni-greifswald.de. To contact editorial author Emad M. El-Omar, M.D., email e.el-omar@abdn.ac.uk. CHICAGO – Two genome-wide association studies and a subsequent meta-analysis have found that certain genetic variations are associated with susceptibility to Helicobacter…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MAY 7, 2013 Media Advisory: To contact Maurizio Gasparini, M.D., email maurizio.gasparini@humanitas.it. To contact editorial author Merritt H. Raitt, M.D., call Tamara Hargens-Bradley at 503-494-8231 or email hargenst@ohsu.edu. CHICAGO – Programming an implantable cardioverter-defibrillator (ICD) with a long-detection interval compared with a standard-detection interval resulted in a reduction…

EMBARGOED FOR EARLY RELEASE: 6 P.M. (CT) SUNDAY, MAY 5, 2013 Media Advisory: To contact Emily Y. Chew, M.D., call Jean Horrigan at 301-496-5248 or email jh@nei.nih.gov. CHICAGO – In a large, multicenter, randomized clinical trial that included persons at high risk for progression to advanced age-related macular degeneration (AMD), adding the carotenoids lutein and…

EMBARGOED FOR EARLY RELEASE: 8:15 A.M. (CT) SUNDAY, MAY 5, 2013 Media Advisory: To contact Barbara Schmidt, M.D., M.Sc., call Alison Fraser at 267-426-6054 or email FraserA1@email.chop.edu. To contact editorial co-author Eduardo Bancalari, M.D., call Lisa Worley at 305-243-5184 or email LWorley2@med.miami.edu. CHICAGO – In a randomized trial performed to help resolve the uncertainty about…

EMBARGOED FOR EARLY RELEASE: 11:15 A.M. (CT) SATURDAY, MAY 4, 2013 Media Advisory: To contact corresponding author Bethany J. Foster, M.D., M.Sc., call Julie Robert at 514-934-1934 ext. 71381; or email julie.robert@muhc.mcgill.ca. CHICAGO – In a study that included more than 20,000 patients, there was a significant decrease in the United States in mortality rates…

EMBARGOED FOR EARLY RELEASE: 10 A.M. (ET) TUESDAY, APRIL 30, 2013 Antiretroviral Regimen Associated With Less Virological Failure Among HIV-Infected Children Elizabeth D. Lowenthal, M.D., M.S.C.E., of the University of Pennsylvania Perelman School of Medicine and Children’s Hospital of Philadelphia, and colleagues conducted a study to determine whether there was a difference in time to…

EMBARGOED FOR EARLY RELEASE: 10 A.M. (ET) TUESDAY, APRIL 30, 2013 Media Advisory: To contact David A. Brent, M.D., call Cristina Mestre at 412-586-9776 or email mestreca@upmc.edu. NEW YORK – Childhood adversity can lead to chronic physical and mental disability in adult life and have an effect on the next generation, underscoring the importance of…

EMBARGOED FOR EARLY RELEASE: 10 A.M. (ET) TUESDAY, APRIL 30, 2013 Media Advisory: To contact Jonathan M. Davis, M.D., call Julie Jette at 617-636-3265 or email jjette@tuftsmedicalcenter.org. NEW YORK – Among infants with neonatal abstinence syndrome (NAS; caused by in utero opioid exposure), variants in certain genes were associated with a shorter length of hospital…

EMBARGOED FOR EARLY RELEASE: 10 A.M. (ET) TUESDAY, APRIL 30, 2013 Media Advisory: To contact Simon R. M. Dobson, M.D., call Brian Lin at 604-822-2234 or email brian.lin@ubc.ca. To contact editorial co-author Jessica A. Kahn, M.D., M.P.H., call Nick Miller at 513-803-6035 or email nicholas.miller@cchmc.org. NEW YORK – With the number of doses and cost…

EMBARGOED FOR EARLY RELEASE: 10 A.M. (ET) TUESDAY, APRIL 30, 2013 Media Advisory: To contact Hope Weiler, R.D., Ph.D., email hope.weiler@mcgill.ca. To contact editorial author Steven A. Abrams, M.D., call Dipali Pathak at 713-798-4712 or email pathak@bcm.edu. NEW YORK – In a comparison of the effect of different dosages of vitamin D supplementation in breastfed…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 23, 2013 Study Examines Trends in Firearm Injuries Among Children and Adolescents “Given recent firearm-related fatalities combined with declining gun research funding, it is important to monitor firearm injuries in youths. Injury death rates are available but provide an incomplete picture of these potentially preventable injuries,” writes…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 23, 2013 Media Advisory: To contact Martin J. London. M.D., call Kristen Bole at 415-476-2743 or email kristen.bole@ucsf.edu. CHICAGO – Patients at elevated cardiac risk who were treated with beta-blockers on the day of or following noncardiac, nonvascular surgery had significantly lower rates of 30-day mortality and…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 23, 2013 Media Advisory: To contact corresponding author Monique V. Chireau, M.D. M.P.H., call Rachel Harrison at 919-419-5069 or email rachel.harrison@duke.edu.  CHICAGO – For women with abdominal pain or vaginal bleeding during early pregnancy, patient history and clinical examination alone are insufficient to indicate or eliminate the…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 23, 2013 Media Advisory: To contact Casper Roed, M.D., email casperroed@hotmail.com or call 011-45-404-33438. CHICAGO – In a study that included nearly 3,000 adults from Denmark, a diagnosis of meningococcal, pneumococcal, or Haemophilus influenzae meningitis in childhood was associated with lower educational achievement and economic self-sufficiency in…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 23, 2013 Media Advisory: To contact Jakob Christensen, Ph.D., email jakob@farm.au.dk. To contact editorial co-author Kimford J. Meador, M.D., call Holly Korschun at 404-727-3990 or email hkorsch@emory.edu. CHICAGO – Maternal use of valproate (a drug used for the treatment of epilepsy and other neuropsychological disorders) during pregnancy…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 16, 2013 Electrocardiographic Abnormality Associated With Increased Risk of Atrial Fibrillation, Congestive Heart Failure “Left anterior fascicular block (LAFB) is considered a benign electrocardiographic (ECG) finding, but its long-term consequences have not been comprehensively studied,” writes Mala C. Mandyam, B.S., of the University of California, San Francisco…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 16, 2013 Media Advisory: To contact corresponding author Andreas M. Zeiher, M.D., email zeiher@em.uni-frankfurt.de. CHICAGO – Treatment that consisted of shock wave (procedure using high-dose ultrasound)-mediated preconditioning of the target heart tissue prior to administration of bone marrow-derived mononuclear cells was associated with significant, albeit modest improvement…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 16, 2013 Media Advisory: To contact corresponding author Luigi Titomanlio, M.D., Ph.D., email luigi.titomanlio@rdb.aphp.fr. To contact editorial co-author Leon G. Epstein, M.D., call Marla Paul at 312-503-8928 or email marla-paul@northwestern.edu. CHICAGO – In a study including children and adolescents 6 to 18 years of age, those who…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 16, 2013 Media Advisory: To contact corresponding author Atul A. Gawande, M.D., M.P.H., call Marjorie Dwyer at 617-432-8416 or email mhdwyer@hsph.harvard.edu. To contact editorial author Uwe E. Reinhardt, Ph.D., call Elisabeth Donahue at 609-258-5988 or email edonahue@Princeton.edu. CHICAGO – Findings of an analysis that included nearly 35,000…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 16, 2013 Media Advisory: To contact Koon Teo, M.B., Ph.D., call Susan Emigh at 905-525-9140, ext. 22555 or email emighs@mcmaster.ca. CHICAGO – Among patients with a coronary heart disease or stroke event from countries with varying income levels, the prevalence of healthy lifestyle behaviors (such as regular…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 9, 2013 New Approaches to Molecular Diagnosis “Advances in understanding the molecular basis of rare and common disorders, as well as in the technology of DNA analysis, are rapidly changing the landscape of molecular genetic and genomic testing,” writes Bruce R. Korf, M.D., Ph.D., of the University…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 9, 2013 Media Advisory: To contact Mingzhao Xing, M.D., Ph.D., call Vanessa Wasta at 410-614-2916 or email wasta@jhmi.edu. To contact editorial co-author Anne R. Cappola, M.D., Sc.M., call Kim Menard at 215-662-6183 or email kim.menard@uphs.upenn.edu. CHICAGO – Presence of the genetic mutation BRAF V600E was significantly associated…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 9, 2013 Media Advisory: To contact corresponding author Michael J. Ackerman, M.D., Ph.D., call Traci Klein at 507-284-5005 or email klein.traci@mayo.edu. To contact editorial co-author Alan E. Guttmacher, M.D., call Robert Bock at 301-496-5133 or email bockr@mail.nih.gov. CHICAGO – In a molecular genetic evaluation involving 91 cases…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 9, 2013 Media Advisory: To contact corresponding author Richard Mayeux, M.D., M.Sc., call Elizabeth Streich at 212-305-3689 or email estreich@columbia.edu. To contact editorial author Robert L. Nussbaum, M.D., call Kristen Bole at 415-476-2743 or email kristen.bole@ucsf.edu. CHICAGO – In a meta-analysis of data from nearly 6,000 African…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 9, 2013 Media Advisory: To contact corresponding author Mark J. Pallen, M.A., M.D., Ph.D., email m.pallen@warwick.ac.uk. To contact editorial author David A. Relman, M.D., call Margarita Gallardo at 650-723-7897 or email mjgallardo@stanford.edu. CHICAGO – Researchers have been able to reconstruct the genome sequence of an outbreak strain…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 2, 2013 The Inevitable Application of Big Data to Health Care “The amount of data being digitally collected and stored is vast and expanding rapidly. As a result, the science of data management and analysis is also advancing to enable organizations to convert this vast resource into…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 2, 2013 Media Advisory: To contact Vance G. Fowler Jr., M.D., M.H.S., call Sarah Avery at 919-660-1306 or email sarah.avery@duke.edu. To contact editorial author Preeti N. Malani, M.D., M.S.J., call Beata Mostafavi at 734-764-2220 or email bmostafa@med.umich.edu. CHICAGO – Use of a vaccine to prevent Staphylococcus aureus…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 2, 2013 Media Advisory: To contact Ciaran J. McMullan, M.D., call Tom Langford at 617-534-1605 or email tlangford@partners.org. CHICAGO – With previous evidence suggesting that melatonin may have a role in glucose metabolism, researchers have found an independent association between decreased secretion of melatonin and an increased…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 2, 2013 Media Advisory: To contact Karen E. Joynt, M.D., M.P.H., call Todd Datz at 617-432-8413 or email tdatz@hsph.harvard.edu. To contact editorial author John P. A. Ioannidis, M.D., D.Sc., call Margarita Gallardo at 650-723-7897 or email mjgallardo@stanford.edu. CHICAGO – In an analysis that included data on more…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 2, 2013 Media Advisory: To contact Ellen M. Lavoie Smith, Ph.D., call Nicole Fawcett at 734-764-2220 or email nfawcett@umich.edu; or call Mary Beth Lewis at 734-763-1682 or email lewismb@umich.edu. CHICAGO –Among patients with painful chemotherapy-induced peripheral neuropathy, use of the anti-depressant drug duloxetine for 5 weeks re­sulted…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 26, 2013 Media Advisory: To contact Josje Altenburg, M.D., email j.altenburg@mca.nl. To contact David J. Serisier, M.B.B.S., D.M., F.R.A.C.P., email david.serisier@mater.org.au. To contact editorial co-author J. Stuart Elborn, M.D., email s.elborn@qub.ac.uk. CHICAGO – Among patients with the lung disorder non-cystic fibrosis bronchiectasis, treatment with the antibiotic azithromycin…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 26, 2013 The Economics of Genomic Medicine – Insights From the IOM Roundtable on Translating Genomic-Based Research for Health In this Viewpoint, W. Gregory Feero, M.D., Ph.D., of the Maine-Dartmouth Family Medicine Residency, Augusta, Maine (Dr. Feero is also Contributing Editor, JAMA), and colleagues discuss several of…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 26, 2013 Media Advisory: To contact Sandra Y. Lin, M.D., call David March at 410-955-1534 or email dmarch1@jhmi.edu. To contact editorial author Harold S. Nelson, M.D., call Adam Dormuth at 303-398-1082 or email DormuthA@NJHealth.org. CHICAGO – In an examination of a type of treatment for allergic rhinitis…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 26, 2013 Media Advisory: To contact Gervasio A. Lamas, M.D., call Joanna Palmer at 305-674-2589 or email Jpalmer2@msmc.com. To contact editorial co-author Howard Bauchner, M.D., call Jann Ingmire at 312-464-2499 or email jann.ingmire@jamanetwork.org. To contact editorial author Steven E. Nissen, M.D., call Wyatt DuBois at 216-445-9946 or…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 19, 2013 Health Services Innovation – The Time is Now “Biomedical innovation has improved prevention, diagnosis, and treatment resulting in reduction in mortality for most diseases. However, health and health care disparities remain across the life-span because these advances have not been matched by advances in delivering…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 19, 2013 Media Advisory: To contact Steven M. Opal, M.D., call David Orenstein at 401-863-1862 or email david_orenstein@brown.edu. CHICAGO – Administration of the drug eritoran to patients with severe sepsis and septic shock failed to demonstrate a significant effect on reducing all-cause 28-day mortality or 1-year mortality,…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 19, 2013 Media Advisory: To contact corresponding author Frank-Erik de Leeuw, M.D., Ph.D., email H.deLeeuw@neuro.umcn.nl. To contact editorial author Graeme J. Hankey, M.D., F.R.C.P., F.R.C.P. Edin., F.R.A.C.P., email graeme.hankey@uwa.edu.au. CHICAGO – In an examination of long-term mortality after stroke, adults 50 years of age and younger who…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 19, 2013 Media Advisory: To contact Maria C. Raven, M.D., M.P.H., M.Sc., call Elizabeth Fernandez at 415-514-1592 or email efernandez@pubaff.ucsf.edu. To contact editorial author James G. Adams, M.D., call Erin White at 847-491-4888 or email ewhite@northwestern.edu. CHICAGO – Among patients with emergency department (ED) visits with the…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 12, 2013 Teaching Physicians to Care Amid Chaos Allan S. Detsky, M.D., Ph.D., of the University of Toronto, and Donald M. Berwick, M.D., of Harvard Medical School, Boston, examine the changes that have taken place in patient care in recent decades. “In 2013, inpatient medical care in…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 12, 2013 Media Advisory: To contact Adnan K. Chhatriwalla, M.D., call Kerry A. O’Connor at 816-932-8646 or email koconnor@saint-lukes.org. CHICAGO – In a study that included 3.3 million percutaneous coronary intervention (PCI; procedures such as balloon angioplasty or stent placement used to open narrowed coronary arteries) procedures,…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 12, 2013 Media Advisory: To contact co-author R. Doug McEvoy, M.D., email doug.mcevoy@health.sa.gov.au. CHICAGO – Among patients who were identified as likely having moderate to severe obstructive sleep apnea, treatment based in primary care was not clinically inferior to treatment at a specialist sleep center for improvement…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 12, 2013 Media Advisory: To contact Richard M. Martin, Ph.D., email richard.martin@bristol.ac.uk. CHICAGO – In research that included nearly 14,000 healthy infants in Belarus, an intervention that succeeded in improving the duration and exclusivity of breastfeeding during infancy did not result in a lower risk of overweight…

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 12, 2013 Media Advisory: To contact corresponding author Carole Clair, M.D., M.Sc., email carole.willi@gmail.com. To contact co-author James B. Meigs, M.D., M.P.H., call Ryan Donovan at 617-724-6433 or email rcdonovan@partners.org. To contact editorial co-author Michael C. Fiore, M.D., M.P.H., M.B.A., call Christopher Hollenback at 608-262-3902 or email…

EMBARGOED FOR EARLY RELEASE: 1:15 P.M. (CT) MONDAY, MARCH 11, 2013 Media Advisory: To contact Mihai Gheorghiade, M.D., call Erin White at 847-491-4888 or email ewhite@northwestern.edu. CHICAGO – Among patients hospitalized for heart failure (HF) with reduced left ventricular ejection fraction (LVEF; a measure of how well the left ventricle of the heart pumps with…

EMBARGOED FOR EARLY RELEASE: 1:30 P.M. (CT) MONDAY, MARCH 11, 2013 Media Advisory: To contact Margaret M. Redfield, M.D., call Traci Klein at 507-990-1182 or email klein.traci@mayo.edu. CHICAGO – Among patients with heart failure with preserved ejection fraction (a measure of heart function), administration of sildenafil for 24 weeks, compared with placebo, did not result…

EMBARGOED FOR EARLY RELEASE: 10 A.M. (CT) THURSDAY, MARCH 7, 2013 Media Advisory: To contact Jared M. O’Leary, M.D., call Jessica Maki at 617-534-1603 or email jmaki3@partners.org. CHICAGO – Jared M. O’Leary, M.D., of Brigham and Women’s Hospital, Boston, and colleagues analyzed U.S. hospitalizations from 1998 through 2010 for children and adults with congenital heart…