EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 2, 2013 Media Advisory: To contact Ciaran J. McMullan, M.D., call Tom Langford at 617-534-1605 or email tlangford@partners.org. CHICAGO – With previous evidence suggesting that melatonin may have a role in glucose metabolism, researchers have found an independent association between decreased secretion of melatonin and an increased…
Mortality Rates Have Increased at Hospitals in Rural Communities For Certain Conditions Compared to Other Acute Care Hospitals
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 2, 2013 Media Advisory: To contact Karen E. Joynt, M.D., M.P.H., call Todd Datz at 617-432-8413 or email tdatz@hsph.harvard.edu. To contact editorial author John P. A. Ioannidis, M.D., D.Sc., call Margarita Gallardo at 650-723-7897 or email mjgallardo@stanford.edu. CHICAGO – In an analysis that included data on more…
Medication Duloxetine Helps Reduce Pain From Chemotherapy
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, APRIL 2, 2013 Media Advisory: To contact Ellen M. Lavoie Smith, Ph.D., call Nicole Fawcett at 734-764-2220 or email nfawcett@umich.edu; or call Mary Beth Lewis at 734-763-1682 or email lewismb@umich.edu. CHICAGO –Among patients with painful chemotherapy-induced peripheral neuropathy, use of the anti-depressant drug duloxetine for 5 weeks resulted…
JAMA:03262013
Certain Antibiotics May Provide Benefit for Treatment of Respiratory Disorder, Although Increase Risk of Antibiotic Resistance
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 26, 2013 Media Advisory: To contact Josje Altenburg, M.D., email j.altenburg@mca.nl. To contact David J. Serisier, M.B.B.S., D.M., F.R.A.C.P., email david.serisier@mater.org.au. To contact editorial co-author J. Stuart Elborn, M.D., email s.elborn@qub.ac.uk. CHICAGO – Among patients with the lung disorder non-cystic fibrosis bronchiectasis, treatment with the antibiotic azithromycin…
Viewpoint in This Issue of JAMA
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 26, 2013 The Economics of Genomic Medicine – Insights From the IOM Roundtable on Translating Genomic-Based Research for Health In this Viewpoint, W. Gregory Feero, M.D., Ph.D., of the Maine-Dartmouth Family Medicine Residency, Augusta, Maine (Dr. Feero is also Contributing Editor, JAMA), and colleagues discuss several of…
Review Article Examines Sublingual Immunotherapy For Treatment of Allergic Rhinitis and Asthma
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 26, 2013 Media Advisory: To contact Sandra Y. Lin, M.D., call David March at 410-955-1534 or email dmarch1@jhmi.edu. To contact editorial author Harold S. Nelson, M.D., call Adam Dormuth at 303-398-1082 or email DormuthA@NJHealth.org. CHICAGO – In an examination of a type of treatment for allergic rhinitis…
Chelation Therapy May Result in Small Reduction of Risk of Cardiovascular Events, But Findings Do Not Support Routine Clinical Use
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 26, 2013 Media Advisory: To contact Gervasio A. Lamas, M.D., call Joanna Palmer at 305-674-2589 or email Jpalmer2@msmc.com. To contact editorial co-author Howard Bauchner, M.D., call Jann Ingmire at 312-464-2499 or email jann.ingmire@jamanetwork.org. To contact editorial author Steven E. Nissen, M.D., call Wyatt DuBois at 216-445-9946 or…
JAMA:03192013
Viewpoints in This Issue of JAMA
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 19, 2013 Health Services Innovation – The Time is Now “Biomedical innovation has improved prevention, diagnosis, and treatment resulting in reduction in mortality for most diseases. However, health and health care disparities remain across the life-span because these advances have not been matched by advances in delivering…
Drug Does Not Significantly Reduce Risk of Death Among Patients With Severe Sepsis
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 19, 2013 Media Advisory: To contact Steven M. Opal, M.D., call David Orenstein at 401-863-1862 or email david_orenstein@brown.edu. CHICAGO – Administration of the drug eritoran to patients with severe sepsis and septic shock failed to demonstrate a significant effect on reducing all-cause 28-day mortality or 1-year mortality,…
Adults Who Experience Stroke Before Age 50 Have Higher Risk of Death Over Long-Term
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 19, 2013 Media Advisory: To contact corresponding author Frank-Erik de Leeuw, M.D., Ph.D., email H.deLeeuw@neuro.umcn.nl. To contact editorial author Graeme J. Hankey, M.D., F.R.C.P., F.R.C.P. Edin., F.R.A.C.P., email graeme.hankey@uwa.edu.au. CHICAGO – In an examination of long-term mortality after stroke, adults 50 years of age and younger who…
Presenting Health Complaints in Emergency Departments Often Similar Between Cases Requiring Immediate Care or Deemed Non-Urgent
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 19, 2013 Media Advisory: To contact Maria C. Raven, M.D., M.P.H., M.Sc., call Elizabeth Fernandez at 415-514-1592 or email efernandez@pubaff.ucsf.edu. To contact editorial author James G. Adams, M.D., call Erin White at 847-491-4888 or email ewhite@northwestern.edu. CHICAGO – Among patients with emergency department (ED) visits with the…
JAMA:03122013
JAMA_OF:03112013
Viewpoints in This Issue of JAMA
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 12, 2013 Teaching Physicians to Care Amid Chaos Allan S. Detsky, M.D., Ph.D., of the University of Toronto, and Donald M. Berwick, M.D., of Harvard Medical School, Boston, examine the changes that have taken place in patient care in recent decades. “In 2013, inpatient medical care in…
Major Bleeding Following PCI Associated With Increased Risk of Death
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 12, 2013 Media Advisory: To contact Adnan K. Chhatriwalla, M.D., call Kerry A. O’Connor at 816-932-8646 or email koconnor@saint-lukes.org. CHICAGO – In a study that included 3.3 million percutaneous coronary intervention (PCI; procedures such as balloon angioplasty or stent placement used to open narrowed coronary arteries) procedures,…
Study Examines Outcomes for Treatment of Obstructive Sleep Apnea With Primary Care vs. Specialist Care
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 12, 2013 Media Advisory: To contact co-author R. Doug McEvoy, M.D., email doug.mcevoy@health.sa.gov.au. CHICAGO – Among patients who were identified as likely having moderate to severe obstructive sleep apnea, treatment based in primary care was not clinically inferior to treatment at a specialist sleep center for improvement…
Duration of Breastfeeding During Infancy Does Not Reduce a Child’s Risk of Being Overweight, Obese at 11.5 Years
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 12, 2013 Media Advisory: To contact Richard M. Martin, Ph.D., email richard.martin@bristol.ac.uk. CHICAGO – In research that included nearly 14,000 healthy infants in Belarus, an intervention that succeeded in improving the duration and exclusivity of breastfeeding during infancy did not result in a lower risk of overweight…
Regardless of Possible Weight Gain, Quitting Smoking Associated With Reduced Risk of Cardiovascular Disease
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 12, 2013 Media Advisory: To contact corresponding author Carole Clair, M.D., M.Sc., email carole.willi@gmail.com. To contact co-author James B. Meigs, M.D., M.P.H., call Ryan Donovan at 617-724-6433 or email rcdonovan@partners.org. To contact editorial co-author Michael C. Fiore, M.D., M.P.H., M.B.A., call Christopher Hollenback at 608-262-3902 or email…
Addition of Medication to Standard Therapy for Heart Failure Does Not Reduce Risk of Cardiovascular Death or Rehospitalization
EMBARGOED FOR EARLY RELEASE: 1:15 P.M. (CT) MONDAY, MARCH 11, 2013 Media Advisory: To contact Mihai Gheorghiade, M.D., call Erin White at 847-491-4888 or email ewhite@northwestern.edu. CHICAGO – Among patients hospitalized for heart failure (HF) with reduced left ventricular ejection fraction (LVEF; a measure of how well the left ventricle of the heart pumps with…
Use of Sildenafil For Treatment of Heart Failure Does Not Result in Significant Improvement in Exercise Capacity, Clinical Status
EMBARGOED FOR EARLY RELEASE: 1:30 P.M. (CT) MONDAY, MARCH 11, 2013 Media Advisory: To contact Margaret M. Redfield, M.D., call Traci Klein at 507-990-1182 or email klein.traci@mayo.edu. CHICAGO – Among patients with heart failure with preserved ejection fraction (a measure of heart function), administration of sildenafil for 24 weeks, compared with placebo, did not result…
Hospitalizations for Congenital Heart Disease Increasing at Greater Rate Among Adults Than Children
EMBARGOED FOR EARLY RELEASE: 10 A.M. (CT) THURSDAY, MARCH 7, 2013 Media Advisory: To contact Jared M. O’Leary, M.D., call Jessica Maki at 617-534-1603 or email jmaki3@partners.org. CHICAGO – Jared M. O’Leary, M.D., of Brigham and Women’s Hospital, Boston, and colleagues analyzed U.S. hospitalizations from 1998 through 2010 for children and adults with congenital heart…
JAMA_OF:03072013
JAMA:03052013
Also Appearing in This Issue of JAMA
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 5, 2013 Index May Help Predict 10-Year Mortality Among Older Adults “Recent guidelines recommend considering patients’ life expectancy when deciding whether to pursue preventive interventions with long lag times to benefit (≥ 7 years) such as colorectal cancer screening and intensive glycemic control for diabetes. However, most…
Study Examines Thinning of Heart Muscle Wall Among Patients With Coronary Artery Disease
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 5, 2013 Media Advisory: To contact corresponding author Raymond J. Kim, M.D., call Sarah Avery at 919-660-1306 or email sarah.avery@duke.edu. To contact editorial co-author Marc A. Pfeffer, M.D., Ph.D., call Jessica Maki at 617-534-1603 or email jmaki3@partners.org. CHICAGO – Among patients with coronary artery disease referred for…
Scarring of Heart Muscle Associated With Increased Risk of Death in Patients With Type of Cardiomyopathy
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 5, 2013 Media Advisory: To contact corresponding author Sanjay K. Prasad, M.D., email s.prasad@rbht.nhs.uk. CHICAGO – Detection of midwall fibrosis (the presence of scar tissue in the middle of the heart muscle wall) via magnetic resonance imaging among patients with nonischemic dilated cardiomyopathy (a condition affecting the…
Use of Certain Therapies For Inflammatory Diseases Does Not Appear to Increase Risk of Shingles
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, MARCH 5, 2013 Media Advisory: To contact Kevin L. Winthrop, M.D., M.P.H., call Mirabai Vogt at 503-494-7986 or email vogtmi@ohsu.edu. CHICAGO – Although patients with rheumatoid arthritis (RA) have a disproportionately higher incidence of herpes zoster (shingles), an analysis that included nearly 60,000 patients with RA and other…
JAMA:02262013
Viewpoints in This Issue of JAMA
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 26, 2013 Why the Ethics of Parsimonious Medicine Is Not the Ethics of Rationing In this Viewpoint, Jon C. Tilburt, M.D., of the Mayo Clinic, Rochester, Minn., and Christine K. Cassel, M.D., of the American Board of Internal Medicine, Philadelphia, discuss the ethical differences between parsimonious medicine…
Long-Term Use of Medication May Improve Heart Function, But Does Not Improve Symptoms, Quality of Life for Heart Failure Patients
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 26, 2013 Media Advisory: To contact corresponding author Burkert Pieske, M.D., email burkert.pieske@medunigraz.at. To contact editorial co-author John G. F. Cleland, M.D., Ph.D., F.R.C.P., email J.G.Cleland@hull.ac.uk. CHICAGO – Among patients with heart failure with preserved ejection fraction, long-term treatment with the medication spironolactone improved left ventricular diastolic…
Findings Suggest That Number and Frequency of Surveillance Scans For Small Abdominal Aortic Aneurysms Can Be Reduced For Most Patients
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 26, 2013 Media Advisory: To contact Simon G. Thompson, D.Sc., email sgt27@medschl.cam.ac.uk. CHICAGO – In contrast to the commonly adopted surveillance intervals in current abdominal aortic aneurysm (AAA) screening programs, surveillance intervals of several years may be clinically acceptable for the majority of patients with small AAA,…
No Significant Difference Seen in Bariatric Surgery Complications Rates Following Restricting Coverage to Higher-Quality Centers
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 26, 2013 Media Advisory: To contact Justin B. Dimick, M.D., M.P.H., call Shantell Kirkendoll at 734-764-2220 or email smkirk@umich.edu. To contact Caprice C. Greenberg, M.D., M.P.H., call Susan Lampert Smith at 608-890-5643 or email SSmith5@uwhealth.org. CHICAGO – In an analysis of data on patients who underwent bariatric…
Study Finds Small Increase in Incidence of Advanced Breast Cancer Among Younger Women
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 26, 2013 Media Advisory: To contact Rebecca H. Johnson, M.D., call Alyse Bernal at 206-987-5213 or email alyse.bernal@seattlechildrens.org. CHICAGO – An analysis of breast cancer trends in the U.S. finds a small but statistically significant increase in the incidence of advanced breast cancer for women 25 to…
JAMA:02192013
Also Appearing in This Issue of JAMA
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 19, 2013 Opioid Analgesics Involved in Most Pharmaceutical Overdose Deaths “Data recently released by the National Center for Health Statistics show drug overdose deaths increased for the 11th consecutive year in 2010. Pharmaceuticals, especially opioid analgesics, have driven this increase. Other pharmaceuticals are involved in opioid overdose…
Association Found Between Length of Biological Marker and Development of Respiratory Infection in Healthy Adults
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 19, 2013 Media Advisory: To contact Sheldon Cohen, Ph.D., call Shilo Rea at 412-268-6094 or email shilo@cmu.edu. CHICAGO – Among healthy adults who were administered a cold virus, those with shorter telomere length (a structure at the end of a chromosome) in certain cells were more likely…
Intravenous Fluid Used to Increase Blood Volume in Critically Ill Patients Associated With Increased Risk of Death, Kidney Injury
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 19, 2013 Media Advisory: To contact Ryan Zarychanski, M.D., M.Sc., call Ilana Simon at 204-789-3427 or email ilana.simon@med.umanitoba.ca. To contact editorial author Massimo Antonelli, M.D., email m.antonelli@rm.unicatt.it. CHICAGO – In an analysis of studies that examined critically ill patients requiring an increase in blood fluid volume, intravenous…
Increase Seen in Use Of Robotically-Assisted Hysterectomy For Benign Gynecologic Disorders
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 19, 2013 Media Advisory: To contact Jason D. Wright, M.D., call the Columbia University Medical Center Office of Communications at 212-305-3900 or email cumcnews@columbia.edu. To contact editorial co-author Joel S. Weissman, Ph.D., call Lori Schroth at 617-534-1604 or email ljschroth@partners.org. CHICAGO –Between 2007 and 2010, the use…
JAMA:02122013
Viewpoints in This Issue of JAMA
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 12, 2013 Improving Access to Mental Health Services for Youth in the United States “In the wake of the recent school shooting in Newtown, Connecticut, a public dialogue emerged about the accessibility of mental health care in the United States. Policy makers have called for a more…
Higher Number of Doses of Malaria Preventive Therapy During Pregnancy Associated With Better Outcomes for Infants in Africa
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 12, 2013 Media Advisory: To contact corresponding author Feiko O. ter Kuile, Ph.D., email terkuile@liv.ac.uk. CHICAGO – Among pregnant women in sub-Saharan Africa, intermittent preventive therapy for malaria with 3 or more doses of the drug regimen sulfadoxine-pyrimethamine was associated with a higher birth weight and lower…
No Strong Association Found Between Hospital Readmission and Mortality Rates For Medicare Patients Admitted for Heart Attack, Pneumonia, Heart Failure
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 12, 2013 Media Advisory: To contact Harlan M. Krumholz, M.D., S.M., call Karen Peart at 203-432-1326 or email karen.peart@yale.edu. CHICAGO – In a study that included data on nearly 3 million hospital admissions for Medicare beneficiaries with heart attack, pneumonia or heart failure, researchers failed to find…
Newer, Shorter-Course Antibiotic Shows Similar Effectiveness For Treating Skin Infection
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 12, 2013 Media Advisory: To contact Philippe Prokocimer, M.D., call Laura Kempke or Andrew Law at 781-684-0770 or email trius@mslgroup.com. To contact editorial co-author Helen W. Boucher, M.D., call Julie Jette at 617-636-3265 or email jjette@tuftsmedicalcenter.org. CHICAGO – Treatment with a newer antibiotic, tedizolid phosphate, once daily…
Study Identifies Factors Associated With Eradication of Bacteria Linked to Gastric Cancer
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 12, 2013 Media Advisory: To contact Douglas R. Morgan, M.D., M.P.H., call Craig Boerner at 615- 322-4747 or email craig.boerner@vanderbilt.edu. CHICAGO – In an analysis of the results of interventions to eradicate the bacterium Helicobacter pylori (a risk factor for gastric cancer) in seven diverse community populations…
Prenatal Folic Acid Supplementation Associated With Lower Risk of Autism
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 12, 2013 Media Advisory: To contact Pal Surén, M.D., M.P.H., email pal.suren@fhi.no. To contact editorial co-author Robert J. Berry, M.D., M.P.H.T.M., call CDC Media Relations at 404-639-3286 or email media@cdc.gov. CHICAGO – In a study that included approximately 85,000 Norwegian children, maternal use of supplemental folic acid…
JAMA:02052013
Also Appearing in This Issue of JAMA
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 5, 2013 Study Examines Rate of Antipsychotic Use Among Nursing Home Residents “The prescribing of antipsychotic medications persists at high levels in U.S. nursing homes (NHs) despite extensive data demonstrating marginal clinical benefits and serious adverse effects, including death. However, imprecise and outdated data have limited the…
Corticosteroid Injection, Physiotherapy Do Not Provide Significant Improvement for ‘Tennis Elbow’
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 5, 2013 Media Advisory: To contact corresponding author Bill Vicenzino, Ph.D., email b.vicenzino@uq.edu.au. CHICAGO – Among patients with chronic unilateral lateral epicondylalgia (“tennis elbow”), a single injection of corticosteroid medication was associated with poorer outcomes after one year and higher recurrence rates compared with placebo, while eight…
Use of ACE Inhibitor by Patients With Peripheral Artery Disease May Improve Pain-Free Walking, Physical Functioning
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 5, 2013 Media Advisory: To contact Anna A. Ahimastos, Ph.D., email A.Ahimastos@alfred.org.au. To contact editorial author Mary McGrae McDermott, M.D., call Marla Paul at 312-503-8928 or email marla-paul@northwestern.edu. CHICAGO – Among patients with peripheral artery disease and intermittent claudication (pain in the calf that comes and goes,…
Lower Proportion of Medicare Patients Dying in Hospitals; Increase Seen in Use of ICUs in Last Month of Life
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, FEBRUARY 5, 2013 Media Advisory: To contact Joan M. Teno, M.D., M.S., call David Orenstein at 401-863-1862 or email david_orenstein@brown.edu. To contact editorial co-author Mary E. Tinetti, M.D., call Karen Peart at 203-432-1326 or email karen.peart@yale.edu. CHICAGO – In a study that included data on more than 800,000…
JAMA_OF:01222013
Study Evaluates Approaches for Weaning Patients With Tracheostomy From Long-Term Ventilator Support
EMBARGOED FOR EARLY RELEASE: 12:55 P.M. (CT) TUESDAY, JANUARY 22, 2013 Media Advisory: To contact Amal Jubran, M.D., call Maureen Dyman at 708-202-5627 or email Maureen.Dyman@va.gov. CHICAGO – Among patients with a tracheostomy requiring prolonged mechanical ventilation and treated at a single long-term care facility, unassisted breathing using an oxygen delivery device connected to a…
JAMA:01222013
Also Appearing in This Issue of JAMA
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 22, 2013 Study Identifies What Type of Hospitals are More Likely to Receive Penalties For Failing to Reduce Hospital Readmissions “The federal Hospital Readmissions Reduction Program (HRRP) took effect on October 1, 2012, the first day of fiscal year 2013. Under this program, using claims data from…
Hospital Readmission for Older Patients Often For Different Illness
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 22, 2013 Media Advisory: To contact corresponding author Harlan M. Krumholz, M.D., S.M., call Karen Peart at 203-432-1326 or email karen.peart@yale.edu. CHICAGO – Among approximately 3 million Medicare patients hospitalized for heart failure, heart attack, or pneumonia, readmissions were frequent throughout the 30 days following the hospitalization,…
Study Evaluates Rehospitalizations and Hospitalizations For Medicare Beneficiaries Following Implementation of Quality Improvement Intervention for Care Transition
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 22, 2013 Media Advisory: To contact corresponding author Joanne Lynn, M.D., M.A., M.S., call Ken Schwartz at 571-733-5709 or email Ken.Schwartz@altarum.org. To contact editorial author Mark V. Williams, M.D., call Marla Paul at 312-503-8928 or email marla-paul@northwestern.edu. CHICAGO – Communities in which quality improvement initiatives for care…
Research Finds Substantial Variation in Readmission Rate Among Children’s Hospitals
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 22, 2013 Media Advisory: To contact Jay G. Berry, M.D., M.P.H., call Meghan Weber at 617-919-3110 or email meghan.weber@childrens.harvard.edu. To contact editorial co-author Rajendu Srivastava, M.D., F.R.C.P.C., M.P.H., call Phil Sahm at 801-581-2517 or email phil.sahm@hsc.utah.edu. CHICAGO – In a national sample of 72 children’s hospitals, 6.5…
Emergency Department Use Within 30 Days of Hospital Discharge Common
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 22, 2013 Media Advisory: To contact Anita A. Vashi, M.D., M.P.H., call Karen Peart at 203-432-1326 or email karen.peart@yale.edu. CHICAGO – In a study that included more than 4 million patients, nearly 20 percent of hospitalizations resulted in at least 1 acute care encounter within the 30…
JAMA:01152013
Viewpoints in This Issue of JAMA
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 15, 2013 Mega-Trials for Blockbusters John P. A. Ioannidis, M.D., D.Sc., of the Stanford University School of Medicine, Stanford, Calif., writes that mega-trials (very large, simple trials) should be conducted for licensed interventions with annual sales that exceed $1 billion, i.e., a blockbuster. These blockbusters “should have…
Absence of Monitoring of Stomach Fluid Volume for Patients on Ventilator and Feeding Tube Does Not Increase Risk of Pneumonia; May Improve Feeding
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 15, 2013 Media Advisory: To contact Jean Reignier, M.D., Ph.D., email jean.reignier@chd-vendee.fr. To contact editorial author Todd W. Rice, M.D., M.Sc., call Craig Boerner at 615-322-4747 or email craig.boerner@vanderbilt.edu. CHICAGO – Patients undergoing mechanical ventilation and receiving nutrition via a feeding tube who did not receive monitoring…
Higher Quality Rating For Medicare Advantage Plan Associated With Increased Likelihood of Plan Enrollment
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 15, 2013 Media Advisory: To contact corresponding author William H. Shrank, M.D., M.S.H.S., call Brian Cook or Isabella Leung of the CMS Press Office at 202-690-6145 or email press@cms.hhs.gov. To contact editorial author Jack Hoadley, Ph.D., call Lauren Mullins at 202-687-2269 or email lm973@georgetown.edu. CHICAGO – In…
Advanced Airway Procedures for Out-of-Hospital Cardiac Arrest Associated With Poorer Neurological Outcomes
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 15, 2013 Media Advisory: To contact Kohei Hasegawa, M.D., M.P.H., call Kristen Stanton at 617-643-3907 or email kstanton3@partners.org. To contact editorial co-author Donald M. Yealy, M.D., call Rick Pietzak at 412-864-4151 or email pietzakr@upmc.edu. CHICAGO – In patients with out-of-hospital cardiac arrest, cardiopulmonary resuscitation with advanced airway…
JAMA:01082013
Viewpoints in This Issue of JAMA
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 8, 2013 How to Decide Whether a Clinical Practice Guideline Is Trustworthy David F. Ransohoff, M.D., of the University of North Carolina School of Medicine, Chapel Hill, and colleagues discuss concerns about the process of developing clinical practice guidelines and the standards for developing practice guidelines created…
Post-Operative Intravenous Acetaminophen May Help Reduce Use of Morphine In Infants
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 8, 2013 Media Advisory: To contact co-author Dick Tibboel, M.D., Ph.D., email d.tibboel@erasmusmc.nl. To contact editorial author Kanwaljeet J. S. Anand, M.B.B.S., D.Phil., F.R.C.P.C.H., call Sheila Champlin at 901-448-4957 or email schampli@uthsc.edu. CHICAGO – Among infants undergoing major surgery, postoperative use of intermittent intravenous paracetamol (acetaminophen) for…
Study Documents Failure Rate of Antibiotic Treatment for Gonorrhea
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 8, 2013 Media Advisory: To contact Vanessa G. Allen, M.D., M.P.H., call Nicole Helsberg at 647-260-7466 or email nicole.helsberg@oahpp.ca. To contact editorial author Robert D. Kirkcaldy, M.D., M.P.H., call the NCHHSTP Media Office at 404-639-8895 or email NCHHSTPMediaTeam@cdc.gov. CHICAGO – In an examination of the effectiveness of…
Vitamin D Supplementation Does Not Reduce Knee Pain, Cartilage Loss in Patients With Osteoarthritis
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 8, 2013 Media Advisory: To contact Timothy McAlindon, D.M., M.P.H., call Julie Jette at 617-636-3265 or email jjette@tuftsmedicalcenter.org. CHICAGO – In a two year randomized trial, patients with symptomatic knee osteoarthritis who received vitamin D supplementation did not have a significant difference in knee pain or cartilage…
JAMA:01012013
Viewpoints in This Week’s JAMA
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 1, 2013 How and Why U.S. Health Care Differs From That in Other OECD Countries Victor R. Fuchs, Ph.D., of Stanford University, Stanford, Calif., compares U.S. health care to that in other countries of the Organization for Economic Co-operation and Development (OECD), and “reaches one inescapable conclusion—U.S….
Maintenance Therapy With Calcium-Channel Blocker to Suppress Premature Labor Does Not Significantly Reduce Adverse Perinatal Outcomes
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 1, 2013 Media Advisory: To contact Carolien Roos, M.D., email c.roos@obgyn.umcn.nl. CHICAGO – In women with threatened (symptoms of) preterm labor, maintenance therapy to suppress labor with the calcium-channel blocker nifedipine for 12 days did not result in a significant reduction in adverse perinatal (just before and…
Study Finds No Significant Difference in Survival Between Patients Who Receive ICDs in Clinical Practice vs. Clinical Trials
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 1, 2013 Media Advisory: To contact Sana M. Al-Khatib, M.D., M.H.S., call Sarah Avery at 919-660-1306 or email sarah.avery@duke.edu. CHICAGO – Comparing the largest registry of implantable cardioverter-defibrillator (ICD) implants in the United States with 2 primary prevention randomized clinical trials, researchers found that patients who met…
Use of Anti-Depressants During Pregnancy Not Associated With Increased Risk of Stillbirth, Infant Death
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 1, 2013 Media Advisory: To contact Olof Stephansson, M.D., Ph.D., email olof.stephansson@ki.se. CHICAGO – In a study that included nearly 30,000 women from Nordic countries who had filled a selective serotonin reuptake inhibitor (SSRI) prescription during pregnancy, researchers found no significant association between use of these medications…
Imaging Study Examines Effect of Fructose on Brain Regions That Regulate Appetite
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 1, 2013 Media Advisory: To contact corresponding author Robert S. Sherwin, M.D., call Helen Dodson at 303-436-3984 or email helen.dodson@yale.edu. To contact editorial co-author Jonathan Q. Purnell, M.D., call Mirabai Vogt at 503-494-7986 or email vogtmi@ohsu.edu. CHICAGO – In a study examining possible factors regarding the associations…
Higher Levels of Obesity Associated With Increased Risk of Death; Being Overweight Associated With Lower Risk of Death
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JANUARY 1, 2013 Media Advisory: To contact Katherine M. Flegal, Ph.D., call Karen Hunter at 404-639-3286 or email ksh7@cdc.gov. To contact editorial co-author Steven B. Heymsfield, M.D., email Steven.heymsfield@pbrc.edu. CHICAGO – In an analysis of nearly 100 studies that included approximately 3 million adults, relative to normal weight,…
JAMA_OF:12212012
JAMA:12252012
Also Appearing in This Issue of JAMA
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, DECEMBER 25, 2012 Obesity May Be Declining Among Preschool-Aged Children Living in Low-Income Families “Obesity and extreme obesity in childhood, which are more prevalent among minority and low-income families, have been associated with other cardiovascular risk factors, increased health care costs, and premature death. Obesity and extreme obesity…
Sustained Virological Response Associated With Improved Survival For Certain Patients With Chronic Hepatitis C Virus Infection
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, DECEMBER 25, 2012 Media Advisory: To contact corresponding author Harry L. A. Janssen, M.D., Ph.D., email h.janssen@erasmusmc.nl. CHICAGO – Among patients with chronic hepatitis C virus infection and advanced hepatic fibrosis (development of excess fibrous connective tissue), sustained virological response (SVR) to interferon-based treatment was associated with a…
Autopsy-Based Study Examines Prevalence of Atherosclerosis Among U.S. Service Members
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, DECEMBER 25, 2012 Media Advisory: To contact Bryant J. Webber, M.D., call Sharon Willis at 301-295-3578 or email sharon.willis@usuhs.edu. To contact editorial author Daniel Levy, M.D., call the NHLBI press office at 301-496-4236 or email nhlbi_news@nhlbi.nih.gov. CHICAGO – Among deployed U.S. service members who died of combat or…
JAMA:12182012
Viewpoints in This Week’s JAMA
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, DECEMBER 18, 2012 Iodine Supplementation During Pregnancy and Lactation Alex Stagnaro-Green, M.D., M.H.P.E., of the George Washington University School of Medicine and Health Sciences, Washington, D.C., and colleagues discuss the possible adverse effects of iodine deficiency and the importance of supplementation during pregnancy and while breastfeeding. “The status…
Administration of Clopidogrel Prior to PCI Associated With Reduction in Major Cardiac Events, But Not Improved Survival
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, DECEMBER 18, 2012 Media Advisory: To contact corresponding author Gilles Montalescot, M.D., Ph.D., email gilles.montalescot@psl.aphp.fr. CHICAGO – Among patients scheduled for a percutaneous coronary intervention (PCI; procedures such as balloon angioplasty or stent placement used to open narrowed coronary arteries), pretreatment with the antiplatelet agent clopidogrel was not…
Intensive Weight-Loss Intervention Associated With Increased Likelihood of Partial Remission From Diabetes, Although Improvement in Rate Modest
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, DECEMBER 18, 2012 Media Advisory: To contact Edward W. Gregg, Ph.D., call Karen Hunter at 404-639-3286 or email ksh7@cdc.gov. To contact editorial co-author David E. Arterburn, M.D., M.P.H., call Joan DeClaire at 206-287-2653 or email declaire.j@ghc.org. CHICAGO – Among overweight adults, participation in an intensive lifestyle intervention (that…
Regular Aspirin Use 10 or More Years Ago Associated With Increased Risk of Type of Age-Related Macular Degeneration
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, DECEMBER 18, 2012 Media Advisory: To contact Barbara E. K. Klein, M.D., M.P.H., call Susan Lampert Smith at 608-262-7335 or email slsmith2@wisc.edu. CHICAGO – Among nearly 5,000 study participants, regular aspirin use reported ten years prior was associated with a small but statistically significant increase in the risk…
World Trade Center Rescue and Recovery Workers Have Had Increased Incidence of Certain Types of Cancer
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, DECEMBER 18, 2012 Media Advisory: To contact co-author Steven D. Stellman, Ph.D., M.P.H., call Jean Weinberg at 347-396-4177 or email jweinberg@health.nyc.gov; or Marcus Liem at 347-396-2919 or email mliem@health.nyc.gov. CHICAGO – Among rescue and recovery workers exposed to the dust, debris, and fumes following the World Trade Center…
JAMA:12112012
Also Appearing in This Issue of JAMA
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, DECEMBER 11, 2012 Study Finds Association Between Weight of Pancreas and Potential Diabetes Biomarker Autopsy and imaging studies suggest that among adults with type 1 diabetes (T1D), their pancreas is smaller and weighs less than the pancreas of adults without the disease. However, it is unknown when pancreatic…
Combination Therapy May Help Decrease Sleep Apnea Symptoms at Higher Altitudes
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, DECEMBER 11, 2012 Media Advisory: To contact corresponding author Konrad E. Bloch, M.D., email konrad.bloch@usz.ch. CHICAGO – For individuals with obstructive sleep apnea traveling to higher altitudes (which may exacerbate symptoms), use of a combination therapy resulted in improvement in symptoms including reduced insomnia and better control of…
Prevalence of Visual Impairment in U.S. Increases
EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, DECEMBER 11, 2012 Media Advisory: To contact corresponding author David S. Friedman, M.D., M.P.H., Ph.D., call John Lazarou at 410-502-8902 or email jlazaro1@jhmi.edu. To contact editorial co-author David C. Musch, Ph.D., M.P.H., call Betsy Nisbet at 734-647-5586 or email bsnisbet@umich.edu. CHICAGO – The prevalence of nonrefractive visual impairment…
JAMA:12042012
Viewpoints in This Week’s JAMA
Embargoed for Release: 3 p.m. CT Tuesday, December 4, 2012 Overcoming the Obstacles to Research During Residency – What Does It Take? Michael B. Rothberg, M.D., M.P.H., of the Cleveland Clinic, writes that “although most physicians work as clinicians and never perform research, the Accreditation Council for Graduate Medical Education requires that residents ‘participate in…
Study Examines Attitudes of Medical Students’ Toward Industry Following COI Disclosures by Preclinical Lecturers
Embargoed for Release: 3 p.m. CT Tuesday, December 4, 2012 Media Advisory: To contact corresponding author Deborah Korenstein, M.D., call Kevin Orozovich at 212-241-9200 or email newsmedia@mssm.edu. Azalea Kim, M.P.A., of the Mount Sinai School of Medicine, New York, and colleagues studied the association between routine conflicts of interest (COI) disclosure with preclinical medical students…
Bias May Exist in Rating of Medical Trainees
Embargoed for Release: 3 p.m. CT Tuesday, December 4, 2012 Media Advisory: To contact Peter Yeates, M.B.B.S., M.Clin.Ed., email peter.yeates@manchester.ac.uk. Peter Yeates, M.B.B.S., M.Clin.Ed., of the University of Manchester, United Kingdom, and colleagues conducted a study to examine whether observations of the performance of postgraduate year 1 physicians influence raters’ scores of subsequent performances. “The…
Research Evaluates Possible Benefit of Multiple Mini-Interviews as Part of Medical School Admission Process
Embargoed for Release: 3 p.m. CT Tuesday, December 4, 2012 Media Advisory: To contact Kevin W. Eva, Ph.D., call Brian Kladko at 604-827-3301 or email brian.kladko@ubc.ca. Kevin W. Eva, Ph.D., of the University of British Columbia, Vancouver, and colleagues conducted a study to determine whether students deemed acceptable through a revised admissions protocol using a…
Clinically Integrated E-Learning of Evidence-Based Medicine Improves Knowledge, Skills in Resource-Limited Countries
Embargoed for Release: 3 p.m. CT Tuesday, December 4, 2012 Media Advisory: To contact corresponding author Khalid S. Khan, M.B.B.S., M.Sc., email k.s.khan@qmul.ac.uk. Regina Kulier, M.D., of the World Health Organization, Geneva, Switzerland, and colleagues conducted a study to evaluate the effects of a clinically integrated e-learning evidence-based medicine (EBM) course on knowledge, skills, and…
Shorter Rotation for Attending Physicians Does Not Appear to Have Adverse Effects on Patients; May Decrease Physician Burnout
Embargoed for Release: 3 p.m. CT Tuesday, December 4, 2012 Media Advisory: To contact Brian P. Lucas, M.D., M.S., call Nancy Di Fiore at 312-942-5159 or email Nancy_DiFiore@rush.edu. Brian P. Lucas, M.D., M.S., of the Cook County Health and Hospitals System and Rush Medical College, Chicago, and colleagues conducted a study to compare the effects…