Study Finds High Variability Among Primary Care Physicians in Rate of PSA Screening of Older Men

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, OCTOBER 15, 2013 Media Advisory: To contact corresponding author James S. Goodwin, M.D., call Raul Reyes at 409-747-0794 or email rareyes@utmb.edu. “No organization recommends prostate-specific antigen (PSA) screening in men older than 75 years. Nevertheless, testing rates remain high,” write Elizabeth Jaramillo, M.D., of the University of Texas…

For Patients with Diabetes, Angioplasty and Bypass Surgery Lead to Similar Long-Term Benefits For Quality of Life

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, OCTOBER 15, 2013 Media Advisory: To contact corresponding author David J. Cohen, M.D., M.Sc., call Kerry O’Connor at 816-932-8646 or email koconnor@saint-lukes.org. For patients with diabetes and coronary artery disease in more than one artery, treatment with coronary artery bypass graft surgery provided slightly better health status and…

JAMA_OF:10092013

JAMA_OF:10082013

Use of Beta-Blocker Helps Achieve Target Heart Rate Level Without Increase In Adverse Outcomes Among Patients In Septic Shock

EMBARGOED FOR EARLY RELEASE: 7 A.M. (CT) WEDNESDAY, OCTOBER 9, 2013 Andrea Morelli, M.D., of the University of Rome, Italy, and colleagues conducted a study to investigate the effect of the short-acting beta-blocker esmolol on the heart rate of patients with severe septic shock and high risk of death. Septic shock is associated with adverse…

Findings Indicate No Difference in Risk of Death in Comparison of Fluid Replacement Therapies for Critically Ill Patients

EMBARGOED FOR EARLY RELEASE: 7 A.M. (CT) WEDNESDAY, OCTOBER 9, 2013 Djillali Annane, M.D., Ph.D., of Raymond Poincare Hospital, Garches, France, and colleagues conducted a study to compare the effects of 2 types of intravenous fluids on survival for critically ill patients in an intensive care unit. Thousands of patients in intensive care units (ICUs)…

Use of Statin Does Not Improve Survival Among Adults With Ventilator-Associated Pneumonia

EMBARGOED FOR EARLY RELEASE: 7 A.M. (CT) WEDNESDAY, OCTOBER 9, 2013 Laurent Papazian, M.D., Ph.D., of Hôpital Nord, Marseille, France, and colleagues conducted a study to determine whether statin therapy decreased day-28 mortality among intensive care unit patients with ventilator-associated pneumonia. Observational studies have reported that statins improve outcomes of various infections. Ventilator-associated pneumonia (VAP)…

Among Critically Ill Patients, Muscle Wasting Occurs Rapidly; More Severe Among Those With Multiorgan Failure

EMBARGOED FOR EARLY RELEASE: 7 A.M. (CT) WEDNESDAY, OCTOBER 9, 2013 Zudin A. Puthucheary, M.R.C.P., of University College London, England, and colleagues conducted a study to characterize and evaluate the time course and pathophysiology of acute muscle loss in critical illness. “Survivors of critical illness experience significant skeletal muscle weakness and physical disability, which can…

Use of Hypothermia Does Not Improve Outcomes for Adults With Severe Meningitis; May Be Harmful

EMBARGOED FOR EARLY RELEASE: 10:15 A.M. (CT) TUESDAY, OCTOBER 8, 2013 Bruno Mourvillier, M.D., of the Université Paris Diderot, Sorbonne Paris Cité, Paris, and colleagues conducted a study to examine whether treatment with hypothermia would improve the functional outcome of comatose patients with bacterial meningitis compared with standard care. Among adults with bacterial meningitis, the…

JAMA:10082013

Despite Evidence Suggesting Comparable Pain Relief at Lower Cost, Treatment Regimen for Bone Metastases Not Widely Used

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, OCTOBER 8, 2013 Media Advisory: To contact Justin E. Bekelman, M.D., call Holly Auer at 215-349-5659 or email holly.auer@uphs.upenn.edu.   Justin E. Bekelman, M.D., of the University of Pennsylvania Perelman School of Medicine, Philadelphia, and colleagues conducted a study to examine whether single-fraction radiation treatment, shown to be…

Chemotherapy Drug Improves Survival Following Surgery for Pancreatic Cancer

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, OCTOBER 8, 2013 Media Advisory: To contact Helmut Oettle, M.D., Ph.D., email Helmut.Oettle@charite.de.   Among patients with pancreatic cancer who had surgery for removal of the cancer, treatment with the drug gemcitabine for 6 months resulted in increased overall survival as well as disease-free survival, compared with observation…

JAMA_OF:10072013

Study Examines Risk Factors For Major Cardiac Events Following Noncardiac Surgery For Patients With Coronary Stents

EMBARGOED FOR EARLY RELEASE: 10 A.M. (CT) MONDAY, OCTOBER 7, 2013 Media Advisory: To contact Mary T. Hawn, M.D., M.P.H., call Tyler Greer at 205-934-2041 or email tgreer@uab.edu. To contact editorial co-author Emmanouil S. Brilakis, M.D., Ph.D., call Lisa Warshaw at 214-648-3404 or email Lisa.Warshaw@utsouthwestern.edu.   Emergency surgery and advanced cardiac disease are risk factors for…

Study Questions Effectiveness of Less-Invasive Surgical Procedure to Detect Cancer in Lymph Nodes Near Breast

EMBARGOED FOR EARLY RELEASE: 10 A.M. (CT) MONDAY, OCTOBER 7, 2013 Media Advisory: To contact corresponding author Kelly K. Hunt, M.D., call Laura Sussman at 713-745-2457 or email lsussman@mdanderson.org. To contact editorial co-author Monica Morrow, M.D., call Courtney A. DeNicola at 646-227-3633 or email Denicolc@mskcc.org.   Judy C. Boughey, M.D., Kelly K. Hunt, M.D., and…

Use of Post-Operative Blood Clot Rate as Measure of Hospital Quality May Be Flawed

EMBARGOED FOR EARLY RELEASE: 10 A.M. (CT) MONDAY, OCTOBER 7, 2013 Media Advisory: To contact Karl Y. Bilimoria, M.D., M.S., call Megan McCann at 312-926-5900 or email memccann@nmh.org. To contact editorial author Edward H. Livingston, M.D., call Jim Michalski at 312-464-5785 or email jim.michalski@jamanetwork.org.   A new study published by JAMA questions using the rate…

JAMA_OF:10042013

Use of Gloves and Gowns For All Patient Contact in ICUs Does Not Reduce Overall Rate of Acquiring MRSA or VRE

EMBARGOED FOR EARLY RELEASE: 6:15 P.M. (CT) FRIDAY, OCTOBER 4, 2013 Media Advisory: To contact Anthony D. Harris, M.D., M.P.H., call Karen Lancaster at 410-328-8919 or email klancaster@umm.edu. To contact editorial author Preeti N. Malani, M.D., M.S.J., call Shantell Kirkendoll at 734-764-2220 or email smkirk@med.umich.edu.   The wearing of gloves and gowns by health care…

JAMA:10012013

Viewpoints Appearing in This Issue of JAMA

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, OCTOBER 1, 2013 Investing in Evidence-Based Care for the Severely Mentally Ill In a Viewpoint, Mark Olfson, M.D., M.P.H., of the New York State Psychiatric Institute, New York, and colleagues discuss the potential implications of giving 4 million previously uninsured people with severe mental disorders health insurance when…

Study Finds Increase in Survival Following Bystander CPR for Out-of-Hospital Cardiac Arrest

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, OCTOBER 1, 2013 Media Advisory: To contact Mads Wissenberg, M.D., email mads.wissenberg.joergensen@regionh.dk. In Denmark between 2001 and 2010 there was an increase in bystander cardiopulmonary resuscitation (CPR) that was associated with an increase in survival following out-of-hospital cardiac arrest, according to a study in the October 2 issue…

Following Bariatric Surgery, Use of Opioids Increases Among Chronic Opioid Users

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, OCTOBER 1, 2013 Media Advisory: To contact Marsha A. Raebel, Pharm.D., call Amy Whited at 303-344-7518 or email Amy.L.Whited@kp.org. To contact editorial author Daniel P. Alford, M.D., M.P.H., call Gina DiGravio at 617-638-8480 or email gina.digravio@bmc.org. In a group of patients who took chronic opioids for noncancer pain…

Extended Follow-up of Hormone Therapy Trials Does Not Support Use For Chronic Disease Prevention

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, OCTOBER 1, 2013 Media Advisory: To contact JoAnn E. Manson, M.D., Dr.P.H., call Tom Langford at 617-534-1605 or email tlangford@partners.org. To contact Elizabeth G. Nabel, M.D., call Lori J. Schroth at 617-534-1604 or email ljschroth@partners.org. Extended follow-up of the two Women’s Health Initiative hormone therapy trials does not…

JAMA:09242013

Also Appearing in This Issue of JAMA

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, SEPTEMBER 24, 2013 Prevalence of Poorer Kidney Function Increases Among Adults 80 Years of Age and Older Recent studies have shown that older adults with chronic kidney disease (CKD; defined as an estimated glomerular filtration rate [GFR; a measure of kidney function] of less than 60 mL/min/1.73 m2)…

Refined Clinical Decision-Making Tool May Help Rule Out Brain Hemorrhage For Patients in Emergency Department With Headache Complaint

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, SEPTEMBER 24, 2013 Media Advisory: To contact Jeffrey J. Perry, M.D., M.Sc., call Jennifer Ganton at 613-798-5555, ext. 73325, or email jganton@ohri.ca. To contact editorial co-author David E. Newman-Toker, M.D., Ph.D., call Stephanie Desmon at 410-955-8665 or email sdesmon1@jhmi.edu. Researchers have developed a simple clinical decision rule that…

Sensor-Augmented Insulin Pump Therapy Reduces Rate of Severe Hypoglycemic Events

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, SEPTEMBER 24, 2013 Media Advisory: To contact corresponding author Timothy W. Jones, M.B.B.S., F.R.A.C.P., M.D., email Tim.Jones@health.wa.gov.au. To contact editorial author Pratik Choudhary, M.B.B.S., M.R.C.P., M.D., email pratik.choudhary@kcl.ac.uk.   Use of an insulin pump with a sensor that suspends insulin delivery when blood glucose falls below a set…

Study Findings Question Frequency of Bone Mineral Density Testing For Predicting Fracture Risk

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, SEPTEMBER 24, 2013 Media Advisory: To contact Sarah D. Berry, M.D., M.P.H., call Jennifer Davis at 617-363-8282 or email jdavis@hsl.harvard.edu. A second bone mineral density (BMD) screening four years after a baseline measurement provided little additional value when assessing risk for hip or other major osteoporotic fracture among…

Combining Diet and Exercise for Knee Osteoarthritis Produces Greater Improvement in Knee Pain, Function

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, SEPTEMBER 24, 2013 Media Advisory: To contact Stephen P. Messier, Ph.D., call Will Ferguson at 336-758-5390 or email ferguswg@wfu.edu. Among overweight and obese adults with knee osteoarthritis, combining intensive diet and exercise led to less knee pain and better function after 18 months than diet-alone and exercise-alone, according…

JAMA:09172013

Among Adults in California, Those With Medicaid Coverage Have Highest Increase in Emergency Department Visits

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, SEPTEMBER 17, 2013 Media Advisory: To contact Renee Y. Hsia, M.D., call Elizabeth Fernandez at 415-514-1592 or email Elizabeth.Fernandez@UCSF.edu. ================================ “Emergency department (ED) use has been affected by insurance patterns over time and will likely be further affected by expansions of coverage from health care reform.” Uninsured patients…

Chronic Care Management Program Does Not Result in Increased Abstinence From Alcohol and Other Drug Dependence

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, SEPTEMBER 17, 2013 Media Advisory: To contact Richard Saitz, M.D., M.P.H., call Gina DiGravio at 617-638-8480 or email gina.digravio@bmc.org. To contact editorial author Patrick G. O’Connor, M.D., M.P.H., call Helen Dodson at 203-436-3984 or email helen.dodson@yale.edu. ============================= Persons with alcohol and other drug dependence who received chronic care…

JAMA:09102013

Use of Electronic Health Records Associated With Higher Rate of Detection of Growth Disorders in Children

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, SEPTEMBER 10, 2013 Media Advisory: To contact corresponding author Leo Dunkel, M.D., Ph.D., email l.dunkel@qmul.ac.uk.   “Monitoring of linear growth is a well-established part of pediatric health care in the developed world. Although monitoring aims to support early diagnosis and timely treatment of disorders affecting growth, such disorders…

Combination Therapy For Severe Alcoholic Hepatitis Does Not Result in Improved Survival

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, SEPTEMBER 10, 2013 Media Advisory: To contact Philippe Mathurin, M.D., email Philippe.Mathurin@chru-lille.fr. To contact editorial co-author Jonathan M. Fenkel, M.D., call Katharine Krauss at 215-955-5507 or email katharine.krauss@jefferson.edu.   Four weeks of treatment with a combination of the drug pentoxifylline and the corticosteroid prednisolone did not improve 6-month…

Use of EHRs For Patients With Diabetes Associated With Reduction in Rates of Emergency Department Visits, Hospitalizations, But Not Office Visits

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, SEPTEMBER 10, 2013 Media Advisory: To contact Mary Reed, Dr.P.H., call Janet Byron at 510-891-3115 or email Janet.L.Byron@kp.org.   Among patients with diabetes, use of an outpatient electronic health record (EHR) in an integrated healthcare delivery system was associated with modest reductions in emergency department visits and hospitalizations,…

Pay-For-Performance Incentive Program for Small Practices With EHRs Results in Improvement in Cardiovascular Outcomes

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, SEPTEMBER 10, 2013 Media Advisory: To contact Naomi S. Bardach, M.D., M.A.S., call Leland Kim at 415-502-NEWS or email Leland.Kim@ucsf.edu. To contact editorial co-author Rowena J. Dolor, M.D., M.H.S., call Sarah Avery at 919-660-1306 or email sarah.avery@duke.edu. A pay-for-performance program in electronic-health-records-(EHR)-enabled small practices led to modest improvements…

Individual Financial Incentives, But Not Practice-Level Incentives, Result In Greater Blood Pressure Control

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, SEPTEMBER 10, 2013 Media Advisory: To contact Laura A. Petersen, M.D., M.P.H., call Graciela Gutierrez at 713-798-4710 or email ggutierr@bcm.edu. In an examination of the effect of financial incentives on hypertension care at 12 outpatient clinics, physician-level (individual) financial incentives, but not practice-level or combined incentives, resulted in…

JAMA_OF:09012013

JAMA_OF:09032013

Medication Does Not Slow Progression of Coronary Disease in Patients with Prehypertension

EMBARGOED FOR EARLY RELEASE: 4:45 A.M. (CT) TUESDAY, SEPTEMBER 3, 2013 Media Advisory: To contact Stephen J. Nicholls, M.B.B.S., Ph.D., email stephen.nicholls@sahmri.com. To contact editorial co-author Jean-Claude Tardif, M.D., call Marie-Josee Nantel at 514-376-3330, ext. 2641; or email Marie-Josee.Nantel@icm-mhi.org. CHICAGO – Among patients with prehypertension and coronary artery disease, use of the renin (an enzyme…

Anticoagulant Does Not Reduce Rate of Ischemic Events Among Certain Patients Undergoing PCI

EMBARGOED FOR EARLY RELEASE: 4:30 A.M. (CT) SUNDAY, SEPTEMBER 1, 2013 Media Advisory: To contact Philippe Gabriel Steg, M.D., email gabriel.steg@bch.aphp.fr.   CHICAGO – Use of the novel anticoagulant otamixaban did not reduce ischemic events compared with unfractionated heparin plus eptifibatide but increased bleeding among patients with non–ST-segment elevation acute coronary syndromes undergoing a percutaneous…

JAMA:09032013

Also Appearing in This Issue of JAMA

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, SEPTEMBER 3, 2013 Hepatitis B Immunization Program in Taiwan Associated With Reduction in Chronic Liver Disease Deaths “Hepatitis B virus (HBV) infection causes infant fulminant hepatitis (IFH), and chronic HBV infection may progress to chronic liver disease (CLD) and hepatocellular carcinoma (HCC). Taiwan launched a nationwide HBV immunization…

Iron Supplementation Among Children Living in Malaria-Endemic Area Does Not Result in Increased Incidence of Malaria

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, SEPTEMBER 3, 2013 Media Advisory: To contact Stanley Zlotkin, M.D., Ph.D., call Caitlin McNamee-Lamb at 416-813-7654, ext. 201436 or email caitlin.mcnamee-lamb@sickkids.ca. To contact editorial author co-author Andrew M. Prentice, Ph.D., email andrew.prentice@lshtm.ac.uk. CHICAGO – Children in a malaria-endemic community in Ghana who received a micronutrient powder with iron…

Comparison of 4 Different Immunization Schedules For Pneumococcal Vaccine Finds No Significant Difference in Antibody Levels

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, SEPTEMBER 3, 2013 Media Advisory: To contact Judith Spijkerman, M.D., email j.spijkerman@umcutrecht.nl. To contact editorial author Katherine L. O’Brien, M.D., M.P.H., call Tim Parsons at 410-955-7619 or email tmparson@jhsph.edu. CHICAGO – The use of 4 different 13-valent pneumococcal conjugate vaccine immunization schedules in healthy term infants resulted in…

Study Evaluates Prevalence of Diabetes Among Adults in China

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, SEPTEMBER 3, 2013 Media Advisory: To contact corresponding authors Guang Ning, M.D., Ph.D., email gning@sibs.ac.cn; Wenhua Zhao, Ph.D., email whzhao@ilsichina.org; or Weiqing Wang M.D., Ph.D., email wqingw@hotmail.com. To contact editorial author Juliana C. N. Chan, M.D., F.R.C.P., email jchan@cuhk.edu.hk. CHICAGO – A study based on a nationally representative…

Multinational Study Suggests Need For Substantial Improvement in Hypertension Diagnosis and Treatment

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, SEPTEMBER 3, 2013 Media Advisory: To contact Clara K. Chow, Ph.D., email cchow@georgeinstitute.org.au or call Veronica McGuire at 905-525-9140, ext. 22169; or email vmcguir@mcmaster.ca. CHICAGO – In a study that included more than 140,000 participants from17 countries of varying income levels, researchers found a large gap between both…

Single Combination Pill For Blood Pressure, Cholesterol, and Platelet Control Provides Benefit to Patients With or at Risk of CVD

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, SEPTEMBER 3, 2013 Media Advisory: To contact Simon Thom, M.B., B.S., M.D., email s.thom@imperial.ac.uk. To contact editorial author J. Michael Gaziano, M.D., M.P.H., call Tom Langford at 617-534-1605 or email tlangford@partners.org. CHICAGO – In a randomized trial that included about 2,000 patients with or at high risk of…

JAMA:08272013

Also Appearing in This Issue of JAMA

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, AUGUST 27, 2013 Reduction Seen in Rates of Gastroenteritis Hospitalizations in Older Children and Adults Since Implementation of Infant Rotavirus Vaccination “Implementation of infant rotavirus vaccination in 2006 has substantially reduced the burden of severe gastroenteritis among U.S. children younger than 5 years,” write Paul A. Gastanaduy, M.D.,…

X-Ray Examination of Ducts During Gallbladder Surgery Not Associated With Significant Reduction in Risk of Common Duct Injury

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, AUGUST 27, 2013 Media Advisory: To contact corresponding author Taylor S. Riall, M.D., Ph.D., call Raul Reyes at 409-747-0794 or email rareyes@utmb.edu. To contact editorial co-author Karl Y. Bilimoria, M.D., M.S., call Marla Paul at 312-503-8928 or email marla-paul@northwestern.edu. CHICAGO – In an analysis of a procedure used…

Genetic Variant Significantly Associated With Increased Coronary Heart Disease Risk in Individuals With Type 2 Diabetes

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, AUGUST 27, 2013 Media Advisory: To contact corresponding author Lu Qi, M.D., Ph.D., call Todd Datz at 617-432-8413 or email tdatz@hsph.harvard.edu; to contact corresponding author Alessandro Doria, M.D., Ph.D., M.P.H., call Jeff Bright at 617-309-1957 or email Jeffrey.bright@joslin.harvard.edu. CHICAGO – Researchers have identified a previously unknown genetic locus…

Study Examines Relationship of a Commercial ACO Contract with Medical Spending for Medicare Beneficiaries Who Were Not Covered By the Contract

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, AUGUST 27, 2013 Media Advisory: To contact J. Michael McWilliams, M.D., Ph.D., call David Cameron at 617-432-0441 or email david_cameron@hms.harvard.edu. CHICAGO – Payment incentives implemented with a commercial accountable care organization (ACO) initiative in Massachusetts –Blue Cross Blue Shield’s Alternative Quality Contract (AQC) – were associated with lower…

Combination Drug Regimen Appears Beneficial for Patients With Hepatitis C and Unfavorable Treatment Characteristics

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, AUGUST 27, 2013 Media Advisory: To contact corresponding author Shyamasundaran Kottilil, M.D., Ph.D., call Anne Oplinger at 301-402-1663 or email AOplinger@niaid.nih.gov. CHICAGO – Treatment of chronic hepatitis C virus (HCV) genotype 1 infection with the interferon-free regimen of sofosbuvir and ribavirin resulted in a high sustained virologic response…

JAMA:08202013

Also Appearing in This Issue of JAMA

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, AUGUST 20, 2013 Study Shows Gypsum Wallboard Does Not Keep Out Carbon Monoxide, Questioning CO Detector Exemptions For Certain Types of Residences “Carbon monoxide (CO) poisoning is a significant U.S. health problem, responsible for approximately 500 accidental deaths annually, and a risk of 18 percent to 35 percent…

Study Examines Genetic Associations for Gastrointestinal Condition in Infants

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, AUGUST 20, 2013 Media Advisory: To contact Bjarke Feenstra, Ph.D., email fee@ssi.dk. CHICAGO – Researchers have identified a new genome-wide significant locus (the place a gene occupies on a chromosome) for infantile hypertrophic pyloric stenosis (IHPS), a serious gastrointestinal condition associated with gastrointestinal obstruction, according to a study…

Lateral Wedge Insoles Not Associated With Improvement of Knee Pain in Osteoarthritis

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, AUGUST 20, 2013 Media Advisory: To contact Matthew J. Parkes, B.Sc., email matthew.parkes@manchester.ac.uk CHICAGO – Although a pooling of data from 12 studies showed a statistically significant association between use of lateral wedge insoles and lower pain in medial knee osteoarthritis, among trials comparing wedge insoles with neutral…

Higher Urinary Albumin Excretion Associated With Increased Risk of Coronary Heart Disease Among Black Adults

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, AUGUST 20, 2013 Media Advisory: To contact Orlando M. Gutierrez, M.D., M.M.Sc., call Tyler Greer at 205-934-2041 or email tgreer@uab.edu. To contact editorial co-author Wolfgang C. Winkelmayer, M.D., Sc.D., call Tracie White at 650-723-7628 or email traciew@stanford.edu. CHICAGO – In a large national study, higher levels of the…

Implementation of Multifaceted Hypertension Quality Improvement Program Associated With Increase in Blood Pressure Control Rates

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, AUGUST 20, 2013 Media Advisory: To contact Marc G. Jaffe, M.D., call Ann Marie Wallace at 510-390-3355 or email ann.m.wallace@kp.org; or call Joe Fragola at 415-902-3737 or email joe.c.fragola@kp.org. To contact editorial co-author Abhinav Goyal, M.D., M.H.S., call Jennifer Johnson McEwen at 404-727-5696 or email jrjohn9@emory.edu. CHICAGO –…

JAMA:08132013

Also Appearing in This Issue of JAMA

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, AUGUST 13, 2013 Study Examines Incidence of Sports-Related Sudden Death in France “Although screening programs prior to participation in sports have been used for many years for young competitive athletes, it has been suggested that screening programs might also be worthwhile in the general population. Description of the…

Earlier Surgical Correction of Heart Valve Disorder Associated With Greater Long-Term Survival, Lower Risk of Heart Failure Risk

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, AUGUST 13, 2013 Media Advisory: To contact Rakesh M. Suri, M.D., D.Phil., call Traci Klein at 507-284-5005 or email Klein.traci@mayo.edu. To contact editorial author Catherine M. Otto, M.D., call Leila Gray at 206-685-0381 or email leilag@uw.edu. CHICAGO – In a study that included patients with mitral valve regurgitation…

Study Identifies Characteristics of Heart Failure Patients More Likely to Benefit From Implantation of Cardiac Resynchronization Device

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, AUGUST 13, 2013 Media Advisory: To contact Pamela N. Peterson, M.D., M.S.P.H., call Jenny Bertrand at 303-520-9591 or email Jennifer.bertrand@dhha.org. CHICAGO – In a large population of Medicare beneficiaries with heart failure who underwent implantation of a cardiac resynchronization therapy defibrillator, patients who had the cardiac characteristics of…

JAMA:08062013

Also Appearing in This Violence/Human Rights Theme Issue of JAMA

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, AUGUST 6, 2013 Number of Scientific Publications on Firearms Shows Modest Increase in Recent Years “In January 1996, Congress passed an appropriations bill amendment prohibiting the U.S. Centers for Disease Control and Prevention (CDC) from using ‘funds made available for injury prevention … to advocate or promote gun…

Research Examines Importance of Identifying Need, Providing Delivery of Mental Health Services Following Community Disasters

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, AUGUST 6, 2013 Media Advisory: To contact Carol S. North, M.D., M.P.E., call Russell Rian at 214-648-3404 or email russell.rian@utsouthwestern.edu. CHICAGO – A review of articles on disaster and emergency mental health response interventions and services indicates that in postdisaster settings, a systematic framework of case identification, triage,…

Treatment for PTSD Does Not Appear to Increase Risk of Drinking Among Individuals With Alcohol Dependence and PTSD

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, AUGUST 6, 2013 Media Advisory: To contact Edna B. Foa, Ph.D., call Steve Graff at 215-349-5653 or email Stephen.Graff@uphs.upenn.edu. To contact editorial author Katherine Mills, Ph.D., email k.mills@unsw.edu.au. CHICAGO – In a trial that included patients with alcohol dependence and posttraumatic stress disorder (PTSD), treatment with the drug…

Mental Disorders But Not Deployment-Related Variables Associated With Suicide Risk Among Current and Former U.S. Military Personnel

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, AUGUST 6, 2013 Media Advisory: To contact Cynthia A. LeardMann, M.P.H., call Karl Van Orden at 619-553-9289 or email Karl.VanOrden@med.navy.mil. To contact editorial author Charles C. Engel, M.D., M.P.H., call Gwendolyn Smalls at 301-295-3981 or email gwendolyn.smalls@usuhs.edu. CHICAGO – In an examination of risk factors associated with suicide…

JAMA:07232013

Also Appearing in This Issue of JAMA

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JULY 23, 2013 Increasing Incidence of Type 1 Diabetes Among Children in Finland Appears to Have Leveled Off “The incidence of type l diabetes (T1D), one of the most prevalent chronic diseases in children, has increased worldwide,” write Valma Harjutsalo, Ph.D., of the Diabetes Prevention Unit, Helsinki, Finland,…

Kidney Stones Associated With Modest Increased Risk of Coronary Heart Disease in Women, But Not Men

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JULY 23, 2013 Media Advisory: To contact Pietro Manuel Ferraro, M.D., email manuel.ferraro@channing.harvard.edu.   CHICAGO – An analysis of data from three studies that involved a total of more than 240,000 participants found that a self-reported history of kidney stones was associated with a statistically significant increased risk…

Survey Assesses Views of Physicians Regarding Controlling Health Care Costs

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JULY 23, 2013 Media Advisory: To contact Jon C. Tilburt, M.D., M.P.H., call Shelly Plutowski at 507-284-5005 or email newsbureau@mayo.edu. To contact editorial co-author Ezekiel J. Emanuel, M.D., Ph.D., call Katie Delach at 215-349-5964 or email Katie.Delach@uphs.upenn.edu. CHICAGO – In a survey of about 2,500 U. S. physicians…

Report Documents Organ Transplantation as Source of Fatal Rabies Virus Case

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JULY 23, 2013 Media Advisory: To contact corresponding author Matthew J. Kuehnert, M.D., call Melissa Dankel at 404-639-4718 or email mdankel@cdc.gov. To contact editorial author Daniel R. Kaul, M.D., call Shantell Kirkendoll at 734-764-2220 or email smkirk@umich.edu. CHICAGO – An investigation into the source of a fatal case…

Difference in Breast Cancer Survival Between Black and White Women Has Not Changed Substantially

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JULY 23, 2013 Media Advisory: To contact Jeffrey H. Silber, M.D., Ph.D., call Dana Mortensen at 267-426-6092 or email mortensen@email.chop.edu. To contact editorial co-author Jeanne S. Mandelblatt, M.D., M.P.H., call Karen Mallet at 215-514-9751 or email km463@georgetown.edu. CHICAGO – In an analysis of 5-year survival rates among black…

JAMA:07162013

Also Appearing in This Issue of JAMA

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JULY 16, 2013 Survival Poor For Nursing Home Residents With Advanced Cognitive Impairment Who Undergo Multiple Hospitalizations For Infections or Dehydration “Multiple hospitalizations for complications from a terminal illness may be burdensome for elderly patients and reflect poor quality care,” write Joan M. Teno, M.D., M.S., of the…

Use of Androgen Deprivation Therapy For Treatment of Prostate Cancer Associ¬ated With Increased Risk of Acute Kidney Injury

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JULY 16, 2013 Media Advisory: To contact corresponding author Samy Suissa, Ph.D., call Tod Hoffman at 514-340-8222, ext. 8661 or email thoffman@jgh.mcgill.ca. CHICAGO – In a study that included more than 10,000 men with nonmetastatic prostate cancer, use of androgen deprivation therapy (ADT) was associated with a significantly…

Combination Therapy May Help Improve Rate of Survival With Favorable Neurological Status Following Cardiac Arrest

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JULY 16, 2013 Media Advisory: To contact Spyros D. Mentzelopoulos, M.D., email sdmentzelopoulos@yahoo.com. CHICAGO – Among patients who experienced in-hospital cardiac arrest requiring vasopressors (drugs that increase blood pressure), use of a combination therapy during cardiopulmonary resuscitation resulted in improved survival to hospital discharge with favorable neurological status,…

Study Examines Characteristics, Features of West Nile Virus Outbreaks

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JULY 16, 2013 Media Advisory: To contact corresponding author Robert W. Haley, M.D., call Russell Rian at 214-648-3404 or email russell.rian@utsouthwestern.edu. To contact Lyle R. Petersen, M.D., M.P.H., call Candice Hoffmann at 404-639-7689 or email hqx5@cdc.gov. To contact editorial author Stephen M. Ostroff, M.D., email sostroff@verizon.net. CHICAGO –…

Longer Duration of Obesity Associated With Subclinical Coronary Heart Disease

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JULY 16, 2013 Media Advisory: To contact Jared P. Reis, Ph.D., call the NHLBI Communications Office at 301-496-4236 or email nhlbi_news@nhlbi.nih.gov. CHICAGO – In a study of adults recruited and followed up over the past 3 decades in the United States, longer duration of overall and abdominal obesity…

JAMA_OF:07102013

Major Study Finds That Overall Population Health in U.S. Has Improved, But Has Not Kept Pace With Other Wealthy Nations

EMBARGOED FOR EARLY RELEASE: 9 A.M. (CT) WEDNESDAY, JULY 10, 2013 Media Advisory: To contact Christopher J. L. Murray, M.D., D.Phil., call William Heisel at 206-897-2886 or email wheisel@uw.edu. To contact editorial author Harvey V. Fineberg, M.D., Ph.D., call Jennifer Walsh at 202-334-2183 or email JWalsh@nas.edu. CHICAGO – In a major study that includes data…

JAMA:07092013

Also Appearing in This Issue of JAMA

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JULY 9, 2013 Dual Antiplatelet Therapy Following Coronary Stent Implantation is Associated With Improved Outcomes Emmanouil S. Brilakis, M.D., Ph.D., of the VA North Texas Health Care System and University of Texas Southwestern Medical Center at Dallas, and colleagues conducted a review of medical literature regarding optimal medical…

Research Examines Differences in Rates of Cardiac Catheterization Between New York State and Ontario

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JULY 9, 2013 Media Advisory: To contact Dennis T. Ko, M.D., M.Sc., call Deborah Creatura at 416-480-4780 or email deborah.creatura@ices.on.ca. CHICAGO – The increased use of cardiac catheterization in New York relative to Ontario appears related to selecting more patients at low risk of obstructive coronary artery disease,…

Soy Protein Supplementation Does Not Reduce Risk of Prostate Cancer Recurrence After Radical Prostatectomy

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JULY 9, 2013 Media Advisory: To contact Maarten C. Bosland, D.V.Sc., Ph.D., call Sherri McGinnis Gonzalez at 312-996-8277 or email smcginn@uic.edu. CHICAGO – Among men who had undergone radical prostatectomy, daily consumption of a beverage powder supplement containing soy protein isolate for 2 years did not reduce or…

Rates of Major Cardiovascular Procedures Differ Between Medicare Advantage and Fee-For-Service Beneficiaries

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JULY 9, 2013 Media Advisory: To contact Daniel D. Matlock, M.D., M.P.H., call Mark Couch at 303-724-5377 or email Mark.Couch@ucdenver.edu. To contact editorial author Harlan M. Krumholz, M.D., S.M., call Karen Peart at 203-432-1326 or email karen.peart@yale.edu. CHICAGO – In a study that included nearly 6 million Medicare Advantage…

Association of Low Vitamin D Levels With Risk of Coronary Heart Disease Events Differs By Race, Ethnicity

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JULY 9, 2013 Media Advisory: To contact corresponding author Ian H. de Boer, M.D., M.S., call Leila Gray at 206-685-0381 or email leilag@uw.edu. To contact corresponding author Keith C. Norris, M.D., call Rachel Champeau at 310-794-0777 or email Rchampeau@mednet.ucla.edu. CHICAGO – In a multiethnic group of adults, low…

JAMA:07022013

Also Appearing in This Issue of JAMA

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JULY 2, 2013 The Paradox of Disease Prevention – Celebrated in Principle, Resisted in Practice In a Special Communication, Harvey V. Fineberg, M.D., Ph.D., of the Institute of Medicine, Washington, D.C., examines a number of the reasons that disease prevention in clinical medicine and public health is often…

Home-Based Walking Exercise Program Improves Speed and Endurance for Patients with PAD

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JULY 2, 2013 Media Advisory: To contact Mary M. McDermott, M.D., call Erin White at 847-491-4888 or email ewhite@northwestern.edu. CHICAGO – In a trial that included nearly 200 participants with peripheral artery disease (PAD), a home-based exercise intervention with a group-mediated cognitive behavioral intervention component improved walking performance…

Study Examines Screening Using Peptide Level and Collaborative Care to Help Reduce Risk of Heart Failure

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JULY 2, 2013 Media Advisory: To contact corresponding author Kenneth McDonald, M.D., email kenneth.mcdonald@ucd.ie or call 353-86-825-5428. To contact editorial author Adrian F. Hernandez, M.D., M.H.S., call Sarah Avery at 919-660-1306 or email sarah.avery@duke.edu. CHICAGO – Among patients at risk of heart failure, collaborative care based on screening…

Study Finds In Vitro Fertilization Associated With Small Increased Risk of Mental Retardation

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JULY 2, 2013 Media Advisory: To contact Sven Sandin, M.Sc., email Sven.Sandin@ki.se. To contact editorial author Marcelle I. Cedars, M.D., call Karin Rush-Monroe at 415-502-NEWS or email Karin.Rush-Monroe@ucsf.edu. CHICAGO – In a study that included more than 2.5 million children born in Sweden, compared with spontaneous conception, any…

Intervention Helps Improve and Maintain Better Blood Pressure Control

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JULY 2, 2013 Media Advisory: To contact Karen L. Margolis, M.D., M.P.H., call Annelise Searle at 952-883-5308 or email Annelise.m.searle@healthpartners.com. To contact editorial co-author David J. Magid, M.D., M.P.H., call Amy Whited at 303-344-7518 or email amy.l.whited@kp.org. CHICAGO – An intervention that consisted of home blood pressure (BP)…

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