MySurgeryRisk Model Predictions of Postoperative Complications and Mortality

Will applying the MySurgeryRisk framework, originally developed and prospectively validated on a single-center dataset, to a large multicenter dataset enhance generalizability without degrading performance?The models predicted postoperative complications in this cohort analysis of 508 097 encounters from 366 875 patients who underwent major operations at 14 health care institutions. Model performance was comparable with the previously validated MySurgeryRisk models, with procedure type and clinician-specific factors identified as the most influential contributors to predicted risk.In this study, incorporating routinely collected variables from a multicenter cohort enabled highly generalizable, accurate prediction of postoperative complications.

Corresponding Author: Azra Bihorac, MD, MS, Intelligent Clinical Care Center, Division of Nephrology, Hypertension, and Renal Transplantation, Department of Medicine, University of Florida, PO Box 100224, Gainesville, FL 32610-0224 (abihorac@ufl.edu).

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