Viewpoint

Research Ethics in Stopping Opioid Use Disorder Medication

JAMA Psychiatry 10.1001/jamapsychiatry.2026.0246

March 18, 2026 at 11:00 AM EDT

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This Viewpoint explores the ethical questions involved in the design and conduct of the RDD trial among individuals stopping medications for opioid use disorder.

Corresponding Author: Roger D. Weiss, MD, Division of Alcohol, Drugs and Addiction, McLean Hospital, 115 Mill St, Belmont, MA 02478 (rweiss@mclean.harvard.edu).

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