Viewpoint

Dopamine-Blocking Antipsychotics—Time for a New Conversation With Patients?

JAMA Psychiatry 10.1001/jamapsychiatry.2025.3572

November 26, 2025 at 11:00 AM EST

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This Viewpoint discusses what the role of dopamine blockers and non–dopamine-blocking antipsychotics may have in psychiatric practice.

Corresponding Author: Stephen R. Marder, MD, University of California Los Angeles David Geffen School of Medicine, Bldg 206, Room 118 West Los Angeles VA HCC, 11301 Wilshire Blvd, Los Angeles, CA 90073 (marder@ucla.edu).

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