Editor's Pick Research Letter

Intra-Arterial Tenecteplase After Endovascular Thrombectomy for Acute Stroke

JAMA 10.1001/jama.2026.17558

September 28, 2026 at 11:00 AM EDT

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This secondary analysis of a randomized clinical trial examines the efficacy of adjunctive intra-arterial tenecteplase 12 months after stroke in patients who received endovascular thrombectomy.

Corresponding Authors: Xiaochuan Huo, PhD, Department of Cerebral Vascular Disease, Neurological Disease Center, Beijing Anzhen Hospital, Capital Medical University, Beijing, No. 2 Anzhen Rd, Chaoyang, Beijing, Beijing 100029, China (huoxiaochuan@126.com); Zhongrong Miao, PhD, Interventional Neuroradiology, Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, No. 119, S Fourth Ring W Rd, Fengtai District, Beijing 100070, China (zhongrongm@163.com).

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