Research Letter

First Antibiotic Prophylaxis Prescription Among Children With Sickle Cell Disease

JAMA Pediatrics 10.1001/jamapediatrics.2026.0653

April 20, 2026 at 11:00 AM EDT

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This cohort study compares antibiotic prophylaxis prescription timing among children with sickle cell disease born between 2008 and 2022 to identify whether suboptimal uptake of antibiotic prophylaxis is due to the timely receipt of the first prescription by 3 months of age.

Corresponding Author: Jiajing Scarlette Shi, MPA, Georgia Health Policy Center, Andrew Young School of Policy Studies, Georgia State University, Eighth Floor, 55 Park Pl NE, Atlanta, GA 30303 (jshi8@gsu.edu).

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