Viewpoint

Hope, Hype, and Trust in Sickle Cell Disease

JAMA Pediatrics 10.1001/jamapediatrics.2025.4749

December 08, 2025 at 11:00 AM EST

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This Viewpoint discusses how to communicate trust for novel rare disease treatments using lessons learned from sickle cell disease.

Corresponding Author: Yoram Unguru, MD, MS, MA, Division of Pediatric Hematology/Oncology, The Herman and Walter Samuelson Children’s Hospital at Sinai, 2401 W Belvedere Ave, Baltimore, MD 21215-5271 (yunguru@lifebridgehealth.org).

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