Validation of an Adaptive Sinonasal Outcome Test

Does an adaptive version of the Sino-Nasal Outcome Test (SNOT) have psychometric validity?In this validation diagnostic study including 1072 patients who completed the adaptive SNOT instrument and 70 patients who had computed tomography of the sinuses, adaptive SNOT scores (arising from 29 potential constituent items) distinguished between patients with better or worse radiological imaging results, had substantial associations with other measures of health, and had reproducible results. The adaptive test demonstrated internal consistency, intrarater reliability, responsiveness to change, and discriminant and convergent validity.In this study, the adaptive SNOT instrument had strong psychometric properties and can serve as a validated instrument that assesses symptom burden and outcomes related to chronic rhinosinusitis and allergic rhinitis in clinical and research settings.

Corresponding Author: Jennifer J. Shin, MD, SM, Department of Otolaryngology-Head and Neck Surgery, Mass General Brigham, 45 Francis St, Boston, MA 02115 (jennifer_shin@meei.harvard.edu).

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