Original Investigation

A Novel Application-Based Test for Rapid Screening of Olfactory Dysfunction

JAMA Otolaryngology–Head & Neck Surgery 10.1001/jamaoto.2025.4965

January 08, 2026 at 11:00 AM EST

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Can a 5-item, mobile application–based olfactory test reliably screen for olfactory dysfunction (OD)?In this diagnostic study including 484 adult participants, a novel, self-administered olfactory screening tool achieved an area under the curve of 0.87, a sensitivity of 74%, and a specificity of 86% for detecting OD.These findings suggest that the novel test has potential as a rapid and reliable OD screening tool in patient care.

Corresponding Author: Carol H. Yan, MD, 200 W Arbor Dr, San Diego, CA 92103 (c1yan@health.ucsd.edu).

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