Percutaneous Ultrasound-Guided Biopsy for Sampling Neck Lesions

Is percutaneous ultrasound-guided core biopsy an effective sampling method for all new neck lesions, including when lymphoma is a differential diagnosis?In this cohort study of 158 biopsies among patients undergoing ultrasound-guided neck biopsies, core-needle biopsy diagnostic yield was 97.9%, with only 2 of 74 proceeding to excisional biopsy (both confirmatory) and no missed lymphoma diagnoses.Image-guided core-needle biopsy may yield a diagnostic specimen sufficient for treatment and may obviate the need for excisional biopsy, even when lymphoma is a differential diagnosis.

Corresponding Author: Jeffrey P. Guenette, MD, MPH, Center for Evidence-Based Imaging, Brigham and Women’s Hospital, 1620 Tremont St, Boston, MA 02120 (jpguenette@bwh.harvard.edu).

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