Original Investigation

Meclizine Use and Subsequent Falls Among Patients With Dizziness

JAMA Otolaryngology–Head & Neck Surgery 10.1001/jamaoto.2025.2052

July 24, 2025 at 11:00 AM EDT

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Is receipt of meclizine by patients with dizziness associated with a risk of falling requiring medical care?In this cohort study of 805 454 patients aged 18 years or older evaluated for dizziness, 8% filled a meclizine prescription, and of those, 9% had a fall resulting in a medical encounter. Receipt of meclizine was associated with a 2.5-fold greater risk of falling among patients aged 65 years or older and a 3-fold greater risk among those aged 18 to 64 years.Meclizine use following dizziness presentation is associated with increased risk of falls among both patients aged 65 years or older and those aged 18 to 64 years.

Corresponding Author: Schelomo Marmor, PhD, MPH, University of Minnesota, 420 Delaware St SE, MMC 195, Minneapolis, MN 55455 (marm0014@umn.edu).

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