Global Axial Length Centile Charts

How do region-specific axial length (AL) centile curves describe and compare AL distributions across populations, and at what ages do regional differences emerge?This pooled cohort study used individual-level data from 147 404 children and 559 799 AL measurements to develop AL centile charts for East Asia and Europe and Australia. East Asian children had longer AL across all centiles; the East Asian 50th percentile approximated the Europe/Australia 85th, with faster early elongation and earlier plateau.These curves could serve as the current reference standard for these regions, supporting interpretation of childhood AL and regional growth trajectories without defining diagnostic thresholds for myopia.

Corresponding Author: Caroline C. W. Klaver, MD, PhD, Erasmus University Medical Center, Rotterdam, the Netherlands (c.c.w.klaver@erasmusmc.nl).

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