Editor's Pick Original Investigation

Road Traffic Noise, Noise Difference Between Residential Facades, and Risk of Parkinson Disease

JAMA Neurology 10.1001/jamaneurol.2026.2262

July 20, 2026 at 11:00 AM EDT

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Is long-term exposure to road traffic noise associated with a higher risk of Parkinson disease? In this cohort study including over 3 million participants, long-term exposure to road traffic noise was associated with a higher risk of Parkinson disease. Having a quiet facade appeared to attenuate the association between noise and risk of Parkinson disease. These findings suggest that road traffic noise may be a risk factor for Parkinson disease and that access to a quiet facade may mitigate the associated risk.

Corresponding Author: Mette Sørensen, PhD, Work, Environment and Cancer, Danish Cancer Institute, Strandboulevarden 49, 2100 Copenhagen Ø, Denmark (mettes@cancer.dk).

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