Neuroretinal Layer Thinning on OCT Imaging and Hemoglobin A in Youth With Type 1 Diabetes

Are retinal layer thickness changes on optical coherence tomography (OCT) imaging in youth with type 1 diabetes associated with glycemic outcomes and diabetic retinopathy?In this cohort study, thinning of the ganglion cell and inner plexiform layer (GCL+IPL) and outer retinal layers was associated with higher hemoglobin A (HbA). There was no difference in total retinal thickness, retinal nerve fiber layer thickness, GCL+IPL thickness, or outer retinal layer thickness by presence or absence of diabetic retinopathy or severity of retinopathy.Neuroretinal layer thinning was observed in youth with type 1 diabetes without clinically apparent retinopathy and was associated with higher HbA.

Corresponding Author: Risa Wolf, MD, Division of Endocrinology, Department of Pediatrics, Johns Hopkins University School of Medicine, 200 N Wolfe St, Ste 3120, Baltimore, MD 21287 (rwolf@jhu.edu).

Link to the article in your story

We encourage you to link out to this article in your story using the link below. It includes an access token that will give free access to the article for your readers up to one year after publication. (The link will be live after the article publishes and embargo is lifted.)

Please see the article for additional information, including full author list, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

Need more information? Contact us.