Orthokeratology, 0.04% Atropine, and 0.01% Atropine for Myopia Control

How do the efficacy and safety of 0.01% atropine compare with 0.04% atropine or orthokeratology in myopia control for older children and adolescents?In this randomized clinical trial of participants aged 8 to 15 years, 0.04% atropine was more effective than 0.01% atropine or orthokeratology for control of myopia. All 3 treatments were well tolerated, with a higher incidence of photophobia in the 0.04% atropine group.These findings support 0.04% atropine as a superior treatment compared with orthokeratology or 0.01% atropine for older children and adolescents with myopia.

Corresponding Authors: Lin Li, MD, PhD, Department of Ophthalmology, Shanghai Ninth People’s Hospital, School of Medicine, Shanghai Jiao Tong University, No. 639 Zhizaoju Rd, Huangpu District, Shanghai 200011, China (lin_li@sjtu.edu.cn); Jianfeng Zhu, MD, Department of Preventative Ophthalmology, Shanghai Eye Diseases Prevention jfzhu1974@hotmail.com).

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