Outcomes of Older Adults With Advanced Cancer Who Prefer Quality of Life vs Prolonging Survival
JAMA Oncology 10.1001/jamaoncol.2026.0072March 05, 2026 at 11:00 AM EST
Do outcomes differ between older adults with advanced cancer who prioritize maintaining quality of life vs extending survival?In this secondary analysis of a large cluster randomized clinical trial including 706 patients, 506 patients (71.7%) prioritized maintaining quality of life over survival. No significant differences were identified in survival, hospitalization, or treatment-related adverse effects between groups.The current oncology care delivery system may not be responsive to the preferences of older adults with advanced cancer.
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