Long-Term Outcomes and Recovery Trajectories in Out-of-Hospital Cardiac Arrest

Does hypothermia after out-of-hospital cardiac arrest affect societal participation or cognitive functioning at 24 months post arrest, and how do these outcomes evolve over time?This follow-up of the randomized clinical Targeted Hypothermia vs Targeted Normothermia After Out-of-Hospital Cardiac Arrest trial found no significant differences in societal participation or cognitive functioning between targeted hypothermia and normothermia at 24 months. Overall recovery was limited beyond 6 months.Targeted hypothermia compared with normothermia did not affect outcomes 24 months post arrest, suggesting no longer-term effect of hypothermia for the explored outcomes; 6 months may suffice as an end point when assessing functional or cognitive outcomes after out-of-hospital cardiac arrest.

Corresponding Author: Malin Hultgren, MD, Skåne University Hospital, Remissgatan 4, 222 42 Lund, Sweden (malin.uusitalo_hultgren@med.lu.se).

Link to the article in your story

We encourage you to link out to this article in your story using the link below. It includes an access token that will give free access to the article for your readers up to one year after publication. (The link will be live after the article publishes and embargo is lifted.)

Please see the article for additional information, including full author list, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

Need more information? Contact us.