Neurological Events Associated With Acute Dengue Infection

What are the risk and excess burden of neurological events following acute dengue infection?In this population-based cohort study that included 65 207 confirmed dengue-infected cases and 1 616 865 uninfected comparators, odds of any composite new-incident neurological event, memory loss, movement disorders, and other neurological events were significantly elevated in acute dengue infection vs uninfected comparators. However, overall excess burden was modest, with less than 1 excess event per 100 cases.The findings suggest that acute dengue infection is associated with higher odds of new-incident neurological events after infection, and older adults should be monitored for a wider spectrum of potential neurological complications following dengue infection.

Corresponding Author: Jue Tao Lim, PhD, Lee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Rd, Singapore 308232 (juetao.lim@ntu.edu.sg).

Link to the article in your story

We encourage you to link out to this article in your story using the link below. It includes an access token that will give free access to the article for your readers up to one year after publication. (The link will be live after the article publishes and embargo is lifted.)

Please see the article for additional information, including full author list, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

Need more information? Contact us.