Burden of Central Nervous System Cancer in the United States, 1990-2021

What were the trends of central nervous system (CNS) cancer burden in the US from 1990 to 2021?In this cross-sectional study, analysis of the Global Burden of Disease Study 2021 data on US CNS cancers revealed that although the incidence rate remained relatively stable, both disability-adjusted life-years and mortality rates declined. However, substantial disparities persisted across geographical location, age, sex, and sociodemographic profile.The persistent disparity in CNS cancer burden highlights the urgent need to reevaluate public health policies and redistribute health care resources to better support marginalized and underserved populations.

Corresponding Authors: Dong Keon Yon, MD, PhD, Department of Pediatrics, Kyung Hee University College of Medicine, 26-6 Kyungheedae-ro, Dongdaemun-gu, Seoul 02453, Republic of Korea (yonkkang@gmail.com); Keun Young Park, MD, PhD, Department of Neurosurgery, Severance Stroke Center, Severance Hospital, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea (kypark78.md@yuhs.ac).

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